Jay P. Reddy, M.D, Ph.D.
Department of Radiation Oncology, Division of Radiation Oncology
About Dr. Reddy
Dr. Jay Reddy is an Assistant Professor of Radiation Oncology at MD Anderson Cancer Center in Houston, TX. He treats both breast and head and neck cancers of all types. Dr. Reddy emphasizes patient-centered care and shared-decision making in his clinical practice. His goal is to tailor treatment to each specific person and situation. Patients can expect a deeply compassionate, thorough, and thoughtful approach to their care.
Dr. Reddy has special interest in the use of stereotactic body radiation for both primary tumors and metastatic disease. He has research interests in clinical informatics and using data to personalize cancer care.
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2011 | Baylor College of Medicine, Houston, TX, USA, MD, Medicine |
| 2010 | Baylor College of Medicine, Houston, TX, USA, PHD, Molecular and Cellular Biology |
| 2003 | University of Cambridge, Cambridge, GBR, M.Phil, Oncology |
| 2002 | Texas Tech University, Lubbock, TX, USA, BS, Cell and Molecular Biology |
Postgraduate Training
| 2013-2017 | Clinical Residency, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2012-2013 | Clinical Internship, Medicine, The University of Texas at Houston Health Sciences Center, Houston, TX |
Board Certifications
| 2018 | American Board of Radiology |
Experience & Service
Institutional Committee Activities
Radiation Oncology Representative, PRS Budget & Finance Committee, 2019 - 2023
Member, Faculty Senate, 2019 - 2021
Honors & Awards
| 2019 | Best of ASTRO Abstract, ASTRO |
| 2017 | Janice Davis Singletary Fellowship for Lymphoma, MD Anderson Cancer Center |
| 2016 | Dr. Mary Fletcher Memorial Award for Compassionate Patient, MD Anderson Cancer Center |
| 2016 | Workshop on Methods in Clinical Cancer Research, AACR/ASCO |
| 2016 | NCCN Oncology Fellows Recognition Program, National Comprehensive Cancer Network 21st Annual Conference |
| 2016 | Susan Papizan Dolan Fellowship in Breast Oncology, MD Anderson Cancer Center |
| 2016 | TRS Travel Grant, Texas Radiological Society |
| 2015 | Best of ASTRO Abstract, ASTRO |
| 2015 | Trainee Research Day Bristol-Myers Squibb Award in Clinical Finalist, MD Anderson Cancer Center |
| 2015 | ARS Young Oncologist Travel Grant, American Radium Society |
| 2015 | TRS Travel Grant, Texas Radiological Society |
| 2014 | Trainee Research Day Bristol-Myers Squibb Award in Clinical Research Winner, MD Anderson Cancer Center |
| 2014 | TRS Travel Grant, Texas Radiological Society |
| 2008 | Dean's Award for Excellence, Baylor College of Medicine |
| 2008 | DOD Breast Cancer Research Program Pre-doctoral Fellowship, Dept. of Defense |
| 2003 | Robert and Janice McNair Foundation Scholar, Baylor College of Medicine |
| 2002 | Gates-Cambridge Scholar, Bill and Melinda Gates Foundation |
| 2001 | Barry M. Goldwater Scholarship, Barry Goldwater Scholarship and Excellence in Education Foundation |
| 2000 | Endocrine Society Student Research Fellowship, The Endocrine Society |
| 1998 | President Scholarship, Texas Tech University |
| 1998 | Robert C. Byrd Scholarship |
| 1998 | Temple Inland Scholarship |
| 1998 | Salutatorian, Lufkin High School |
| 1997 | Eagle Scout |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Ng SP, Wang H, Pollard C, Nguyen T, Bahig H, Fuller CD, Gunn GB, Garden AS, Reddy JP, Morrison WH, Shah S, Rosenthal DI, Frank SJ, Guha-Thakurta N, Ferrarotto R, Hanna EY, Su SY, Phan J. Patient Outcomes after Reirradiation of Small Skull Base Tumors using Stereotactic Body Radiotherapy, Intensity Modulated Radiotherapy, or Proton Therapy. J Neurol Surg B Skull Base 81(6):638-644, 2020. e-Pub 2019. PMID: 33381367.
- Bagley AF, Garden AS, Reddy JP, Moreno AC, Frank SJ, Rosenthal DI, Morrison WH, Gunn GB, Fuller CD, Shah SJ, Ferrarotto R, Sturgis EM, Gross ND, Phan J. Highly conformal reirradiation in patients with prior oropharyngeal radiation: Clinical efficacy and toxicity outcomes. Head Neck 42(11):3326-3335, 2020. e-Pub 2020. PMID: 32776401.
- Engeseth GM, Stieb S, Mohamed ASR, He R, Stokkevåg CH, Brydøy M, Fuller CD, Garden AS, Rosenthal DI, Phan J, Morrison WH, Reddy JP, Wu R, Zhang X, Frank SJ, Brandon Gunn G. Outcome and patterns of radiation associated brain image changes after proton therapy for head and neck skull base cancers. Radiotherapy and Oncology 151:119-125, 2020. e-Pub 2020. PMID: 32679304.
- Mesko S, Wang H, Tung S, Wang C, Pasalic D, Ning MS, Pezzi TA, Moreno AC, Reddy JP, Garden AS, Rosenthal DI, Gunn GB, Frank SJ, Fuller CD, Morrison W, Su SY, Hanna E, Phan J. Stereotactic Ablative Radiotherapy (SABR) for skull base malignancies: a systematic analysis of set-up and positioning accuracy. Pract Radiat Oncol 10(5):363-371, 2020. e-Pub 2020. PMID: 32240823.
- Stieb S, Perez-Martinez I, Mohamed ASR, Rock S, Bajaj N, Deshpande TS, Zaid M, Garden AS, Goepfert RP, Cardoso R, Ferrarotto R, Reddy JP, Phan J, Morrison WH, Rosenthal DI, Koay EJ, Frank SJ, Fuller CD, Gunn GB, MD Anderson Head and Neck Cancer Symptom Working Group. The impact of tongue-deviating and tongue-depressing oral stents on long-term radiation-associated symptoms in oropharyngeal cancer survivors. Clin Transl Radiat Oncol 24:71-78, 2020. e-Pub 2020. PMID: 32642562.
- Pasalic D, Ludmir EB, Allen PK, Thaker NG, Chapman BV, Hanna EY, Su SY, Ferrarotto R, Glisson BS, Reddy JP, Brandon Gunn G, Fuller CD, Phan J, Rosenthal DI, Morrison WH, Garden AS, Frank SJ. Patient-Reported Outcomes, Physician-Reported Toxicities, and Treatment Outcomes in a Modern Cohort of Patients with Sinonasal Cancer Treated Using Proton Beam Therapy. Radiotherapy and Oncology 148:258-266, 2020. e-Pub 2020. PMID: 32417351.
- Grant SR, Hutcheson KA, Ye R, Garden AS, Morrison WH, Rosenthal DI, Brandon Gunn G, Fuller CD, Phan J, Reddy JP, Moreno AC, Lewin JS, Sturgis EM, Ferrarotto R, Frank SJ. Prospective longitudinal patient-reported outcomes of swallowing following intensity modulated proton therapy for oropharyngeal cancer. Radiotherapy and Oncology 148:133-139, 2020. e-Pub 2020. PMID: 32361662.
- Stieb S, Mohamed ASR, Deshpande TS, Harp J, Greiner B, Garden AS, Goepfert RP, Cardoso R, Ferrarotto R, Phan J, Reddy JP, Morrison WH, Rosenthal DI, Frank SJ, Fuller CD, Brandon Gunn G, MD Anderson Head and Neck Cancer Symptom Working Group. Prospective observational evaluation of radiation-induced late taste impairment kinetics in oropharyngeal cancer patients: Potential for improvement over time?. Clin Transl Radiat Oncol 22:98-105, 2020. e-Pub 2020. PMID: 32373720.
- Bahig H, Ng SP, Pollard C, Nguyen TP, Gunn GB, Rosenthal DI, Fuller CD, Frank SJ, Garden AS, Reddy JP, Morrison WH, Ferrarotto R, Hanna EY, DeMonte F, Su SY, Phan J. A prospective evaluation of health-related quality of life after skull base re-irradiation. Head Neck 42(3):485-497, 2020. e-Pub 2019. PMID: 31868271.
- Mesko S, Wang H, Tung S, Wang C, Pasalic D, Chapman BV, Moreno AC, Reddy JP, Garden AS, Rosenthal DI, Gunn GB, Frank SJ, Fuller CD, Morrison W, Phan J. Estimating PTV margins in head and neck stereotactic ablative radiation therapy (SABR) through target site analysis of positioning and intrafractional accuracy. Int J Radiat Oncol Biol Phys 106(1):185-193, 2020. e-Pub 2019. PMID: 31580928.
- Lin TA, Garden AS, Elhalawani H, Elgohari B, Jethanandani A, Ng SP, Mohamed AS, Frank SJ, Glisson BS, Debnam JM, Sturgis EM, Phan J, Reddy JP, Fuller CD, Morrison WH, Skinner HD, Rosenthal DI, Gunn GB. Radiographic retropharyngeal lymph node involvement in human papillomavirus-associated oropharyngeal carcinoma: Patterns of involvement and impact on patient outcomes. Cancer 125(9):1536-1546, 2019. e-Pub 2019. PMID: 30620385.
- Wang H, Yang JN, Zhang X, Li J, Frank SJ, Zhao Z, Luo D, Zhu X, Wang C, Tung S, Garden AS, Rosenthal DI, Fuller CD, Gunn GB, Ghia AJ, Reddy JP, Raza SM, De Monte F, Chambers MS, Brown PD, Su S, Phan J. Treatment-Plan Comparison of Three Advanced Radiation Treatment Modalities for Fractionated Stereotactic Radiotherapy to the Head and Neck. Int J Medical Physics, Clinical Engineering and Radiation Oncology 8:106-120, 2019.
- An Y, Jiang W, Andraos TY, Reddy JP, Yehia ZA, Lloyd S, Duvic M, D'Souza NM, Milgrom SA, Pinnix CC, Oki Y, Smith GL, Wilson LD, Dabaja BS. Multi-institutional Investigation: Circulating CD4:CD8 ratio is a prognosticator of response to total skin electron beam radiation in mycosis fungoides. Radiotherapy and Oncology 131:88-92, 2019. e-Pub 2018. PMID: 30773193.
- Moreno AC, Frank SJ, Garden AS, Rosenthal DI, Fuller CD, Gunn GB, Reddy JP, Morrison WH, Williamson TD, Holliday EB, Phan J, Blanchard P. Intensity modulated proton therapy (IMPT) - The future of IMRT for head and neck cancer. Oral Oncol 88:66-74, 2019. e-Pub 2018. PMID: 30616799.
- Pasalic D, Reddy JP, Edwards T, Pan HY, Smith BD. Implementing an Electronic Data Capture System to Improve Clinical Workflow in a Large Academic Radiation Oncology Practice. JCO Clin Cancer Inform 2:1-12, 2018. PMID: 30652599.
- Reddy JP, Atkinson RL, Larson R, Burks JK, Smith D, Debeb BG, Ruffell B, Creighton CJ, Bambhroliya A, Reuben JM, Van Laere SJ, Krishnamurthy S, Symmans WF, Brewster AM, Woodward WA. Mammary stem cell and macrophage markers are enriched in normal tissue adjacent to inflammatory breast cancer. Breast Cancer Res Treat 171(2):283-293, 2018. e-Pub 2018. PMID: 29858753.
- Kim CR, Kim B, Ning MS, Reddy JP, Liao Z, Tang C, Welsh JW, Mott FE, Shih YT, Gomez DR. Cost Analysis of PET/CT Versus CT as Surveillance for Stage III Non-Small-Cell Lung Cancer After Definitive Radiation Therapy. Clin Lung Cancer 19(4):e517-e528, 2018. e-Pub 2018. PMID: 29685701.
- Reddy JP, Hernandez M, Gunther JR, Dabaja BS, Martin GV, Jiang W, Akhtari M, Allen PK, Atkinson BJ, Smith GL, Pinnix CC, Milgrom SA, Abou Yehia Z, Osborne EM, Oki Y, Lee H, Hagemeister F, Fanale MA. Pre-treatment neutrophil/lymphocyte ratio and platelet/lymphocyte ratio are prognostic of progression in early stage classical Hodgkin lymphoma. Br J Haematol 180(4):545-549, 2018. e-Pub 2017. PMID: 29271057.
- Akhtari M, Milgrom SA, Pinnix CC, Reddy JP, Dong W, Smith GL, Mawlawi O, Abou Yehia Z, Gunther J, Osborne EM, Andraos TY, Wogan CF, Rohren E, Garg N, Chuang H, Khoury JD, Oki Y, Fanale M, Dabaja BS. Reclassifying patients with early-stage Hodgkin lymphoma based on functional radiographic markers at presentation. Blood 131(1):84-94, 2018. e-Pub 2017. PMID: 29038339.
- Bambhroliya A, Van Wyhe RD, Kumar S, Debeb BG, Reddy JP, Van Laere S, El-Zein R, Rao A, Woodward WA. Gene set analysis of post-lactational mammary gland involution gene signatures in inflammatory and triple-negative breast cancer. PLoS One 13(4):e0192689, 2018. e-Pub 2018. PMID: 29617367.
- Ho JC, Dabaja BS, Milgrom SA, Smith GL, Reddy JP, Mazloom A, Young KH, Deng L, Medeiros LJ, Dong W, Allen PK, Andraos TY, Fowler NH, Nastoupil LJ, Oki Y, Fayad LE, Turturro F, Neelapu SS, Westin J, Hagemeister FB, Rodriguez MA, Pinnix CC. Radiation therapy improves survival in patients with testicular diffuse large B-cell lymphoma(). Leuk Lymphoma 58(12):2833-2844, 2017. e-Pub 2017. PMID: 28482717.
- Milgrom SA, Pinnix CC, Chuang H, Oki Y, Akhtari M, Mawlawi O, Garg N, Gunther JR, Reddy JP, Smith GL, Rohren E, Hagemeister FB, Lee HJ, Fayad LE, Dong W, Osborne EM, Abou Yehia Z, Fanale M, Dabaja BS. Early-stage Hodgkin lymphoma outcomes after combined modality therapy according to the post-chemotherapy 5-point score: can residual pet-positive disease be cured with radiotherapy alone?. Br J Haematol 179(3):488-496, 2017. e-Pub 2017. PMID: 28832956.
- Reddy JP, Pettaway CA, Levy LB, Pagliaro LC, Tamboli P, Rao P, Jayaratna I, Hoffman KE. Factors associated with regional recurrence after lymph node dissection for penile squamous cell carcinoma. BJU Int 119(4):591-597, 2017. e-Pub 2016. PMID: 27753187.
- Reddy JP, Lei X, Huang SC, Nicklaus KM, Fingeret MC, Shaitelman SF, Hunt KK, Buchholz TA, Merchant F, Markey MK, Smith BD. Quantitative Assessment of Breast Cosmetic Outcome After Whole-Breast Irradiation. Int J Radiat Oncol Biol Phys 97(5):894-902, 2017. e-Pub 2016. PMID: 28333010.
- Reddy JP, Tang C, Shih T, Kim B, Kim C, Nguyen QN, Welsh J, Benveniste M, Zhang J, Liao Z, Gomez DR. Influence of Surveillance PET/CT on Detection of Early Recurrence After Definitive Radiation in Stage III Non-small-cell Lung Cancer. Clin Lung Cancer 18(2):141-148, 2017. e-Pub 2016. PMID: 27913215.
- Milgrom SA, Dong W, Akhtari M, Smith GL, Pinnix CC, Mawlawi O, Rohren E, Garg N, Chuang H, Yehia ZA, Reddy JP, Gunther JR, Khoury JD, Suki T, Osborne EM, Oki Y, Fanale M, Dabaja BS. Chemotherapy Response Assessment by FDG-PET-CT in Early-stage Classical Hodgkin Lymphoma: Moving Beyond the Five-Point Deauville Score. Int J Radiat Oncol Biol Phys 97(2):333-338, 2017. e-Pub 2016. PMID: 28068241.
- Stecklein SR, Reddy JP, Wolfe AR, Lopez MS, Fouad TM, Debeb BG, Ueno NT, Brewster AM, Woodward WA. Lack of Breastfeeding History in Parous Women with Inflammatory Breast Cancer Predicts Poor Disease-Free Survival. J Cancer 8(10):1726-1732, 2017. e-Pub 2017. PMID: 28819368.
- Shaitelman SF, Stauder MC, Allen P, Reddy J, Lakoski S, Atkinson B, Reddy J, Amaya D, Guerra W, Ueno N, Caudle A, Tereffe W, Woodward WA. Impact of Statin Use on Outcomes in Triple Negative Breast Cancer. J Cancer 8(11):2026-2032, 2017. e-Pub 2017. PMID: 28819403.
- Abou Yehia Z, Mikhaeel GN, Smith G, Pinnix CC, Milgrom SA, Tang C, Jiang W, Fanale MA, Oki Y, Shank JH, Horace T, Reddy J, Akhtari M, Gunther JR, Suki T, Allen PK, Turner S, Mawlawi O, Dabaja BS. Does Bleomycin Lung Toxicity Increase the Risk of Radiation Pneumonitis in Hodgkin Lymphoma. Int J Radiat Oncol Biol Phys 96(5):951-958, 2016. e-Pub 2016. PMID: 27742539.
- Gunther JR, Fanale MA, Reddy JP, Akhtari M, Smith GL, Pinnix CC, Milgrom SA, Yehia ZA, Allen PK, Osborne EM, Mawlawi O, Dabaja BS. Treatment of early-stage unfavorable Hodgkin lymphoma: Efficacy and toxicity of 4 versus 6 cycles of ABVD chemotherapy with radiation. Int J Radiat Oncol Biol Phys 96(1):110-8, 2016. e-Pub 2016. PMID: 27325479.
- Wolfe AR, Bambhroliya A, Reddy JP, Debeb BG, Huo L, Larson R, Li L, Ueno NT, Woodward WA. MiR-33a decreases high-density lipoprotein-induced radiation sensitivity in breast cancer. Int J Radiat Oncol Biol Phys 95(2):791-9, 2016. e-Pub 2016. PMID: 27055396.
- Hein SM, Haricharan S, Johnston AN, Toneff MJ, Reddy JP, Dong J, Bu W, Li Y. Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress. Oncogene 35(11):1461-7, 2016. e-Pub 2015. PMID: 26096929.
- Akhtari M, Reddy JP, Pinnix CC, Allen PK, Osborne EM, Gunther JR, Milgrom SA, Smith GL, Wogan CF, Fowler N, Rodriguez MA, Dabaja B. Primary cutaneous B-cell lymphoma (non-leg type) has excellent outcomes even after very low dose radiation as single-modality therapy. Leuk Lymphoma 57(1):34-8, 2016. e-Pub 2015. PMID: 25860237.
- Reddy JP, Akhtari M, Smith GL, Pinnix C, Osborne EM, Gunther JR, Allen PK, Yehia ZA, Fanale M, Rodriguez MA, Fowler N, Milgrom SA, Wogan CF, Dabaja BS. Outcomes after chemotherapy followed by radiation for stage IIB Hodgkin lymphoma with bulky disease. Clin Lymphoma Myeloma Leuk 15(11):664-670.e2, 2015. e-Pub 2015. PMID: 26321471.
- Reddy JP, Dawood S, Mitchell M, Debeb BG, Bloom E, Gonzalez-Angulo AM, Sulman EP, Buchholz TA, Woodward WA. Antiepileptic drug use improves overall survival in breast cancer patients with brain metastases in the setting of whole brain radiotherapy. Radiotherapy and Oncology 117(2):308-14, 2015. e-Pub 2015. PMID: 26482599.
- Youssef B, Shank J, Reddy JP, Pinnix CC, Farha G, Akhtari M, Allen PK, Fanale MA, Garcia JA, Horace PH, Milgrom S, Smith GL, Nieto Y, Arzu I, Wang H, Fowler N, Rodriguez MA, Dabaja B. Incidence and predictors of Lhermitte's sign among patients receiving mediastinal radiation for lymphoma. Radiotherapy and Oncology 10:206, 2015. e-Pub 2015. PMID: 26407853.
- Pinnix CC, Smith GL, Milgrom S, Osborne EM, Reddy JP, Akhtari M, Reed V, Arzu I, Allen PK, Wogan CF, Fanale MA, Oki Y, Turturro F, Romaguera J, Fayad L, Fowler N, Westin J, Nastoupil L, Hagemeister FB, Rodriguez MA, Ahmed S, Nieto Y, Dabaja B. Predictors of radiation pneumonitis in patients receiving intensity modulated radiation therapy for Hodgkin and non-Hodgkin lymphoma. Int J Radiat Oncol Biol Phys 92(1):175-82, 2015. PMID: 25863764.
- Wolfe AR, Atkinson RL, Reddy JP, Debeb BG, Larson R, Li L, Masuda H, Brewer T, Atkinson BJ, Brewster A, Ueno NT, Woodward WA. High-density and very-low-density lipoprotein have opposing roles in regulating tumor-initiating cells and sensitivity to radiation in inflammatory breast cancer. Int J Radiat Oncol Biol Phys 91(5):1072-80, 2015. PMID: 25832697.
- Lacerda L, Reddy JP, Liu D, Larson R, Li L, Masuda H, Brewer T, Debeb BG, Xu W, Hortobágyi GN, Buchholz TA, Ueno NT, Woodward WA. Simvastatin radiosensitizes differentiated and stem-like breast cancer cell lines and is associated with improved local control in inflammatory breast cancer patients treated with postmastectomy radiation. Stem Cells Transl Med 3(7):849-56, 2014. e-Pub 2014. PMID: 24833589.
- Haricharan S, Dong J, Hein S, Reddy JP, Du Z, Toneff M, Holloway K, Hilsenbeck SG, Huang S, Atkinson R, Woodward W, Jindal S, Borges VF, Gutierrez C, Zhang H, Schedin PJ, Osborne CK, Tweardy DJ, Li Y. Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy. Elife 2:e00996, 2013. e-Pub 2013. PMID: 24381245.
- Reddy JP, Li Y. Oncogene-induced senescence and its role in tumor suppression. J Mammary Gland Biol Neoplasia 16(3):247-56, 2011. e-Pub 2011. PMID: 21681694.
- Reddy JP, Levy L, Oh JL, Strom EA, Perkins GH, Buchholz TA, Woodward WA. Long-term outcomes in patients with isolated supraclavicular nodal recurrence after mastectomy and doxorubicin-based chemotherapy for breast cancer. Int J Radiat Oncol Biol Phys 80(5):1453-7, 2011. e-Pub 2010. PMID: 21168284.
- Reddy JP, Peddibhotla S, Bu W, Zhao J, Haricharan S, Du YC, Podsypanina K, Rosen JM, Donehower LA, Li Y. Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Proc Natl Acad Sci U S A 107(8):3728-33, 2010. e-Pub 2010. PMID: 20133707.
- Reddy JP, Li Y. The RCAS-TVA system for introduction of oncogenes into selected somatic mammary epithelial cells in vivo. J Mammary Gland Biol Neoplasia 14(4):405-9, 2009. e-Pub 2009. PMID: 19936988.
Invited Articles
- Garden AS, Reddy JP. Postoperative Radiation Therapy for Metastatic Cervical Adenopathy. Semin Radiat Oncol 29(2):144-149, 2019. PMID: 30827452.
- Reddy JP, Smith BD. Invited Commentary on: “Estrogen Receptor Status and the Future Burden of Invasive and In Situ Breast Cancers in the United States.”. Breast Diseases: A Year Book Quarterly, 2015.
Book Chapters
- Reddy JP, Woodward W. Early-Stage Breast Cancer (ESBC). In: Pocket Radiation Oncology. Wolters Kluwer: China, 8-6, 2019.
- Reddy JP, Garden AS. Oropharynx. In: Pocket Radiation Oncology. Wolters Kluwer: China, 5-5, 2019.
- Moningi S, Martin GV, Reddy JP. Radiation Therapy Complications Leading to Critical Illness. In: Oncologic Critical Care. Springer, Cham, 2019.
Patient Reviews
CV information above last modified August 24, 2024