Jennifer M. Mitchell, VMD
Department of Veterinary Medicine and Surgery, Division of Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Veterinary Medicine and Surgery, Division of Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX
Deputy Department Chair, Department of Veterinary Medicine and Surgery, Division of Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX
Section Chief, South Campus Animal Resources, Department of Veterinary Medicine and Surgery, Division of Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2007 | University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, US, Veterinary Medicine, VMD |
| 2003 | Drexel University College of Medicine, Philadelphia, Pennsylvania, US, Laboratory Animal Science, MLAS |
| 1999 | Georgetown University, Washington, DC, US, Biology, BS |
Board Certifications
| 2017 | American College of Laboratory Animal Medicine |
Experience & Service
Academic Appointments
Assistant Professor, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2021
Instructor, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2014
Administrative Appointments/Responsibilities
Deputy Department Chair, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - Present
Section Chief, South Campus Animal Resources, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - Present
Section Chief ad Interim, South Campus Animal Resources, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2019
Other Appointments/Responsibilities
Reserve Veterinary Medical Officer - National Animal Health Emergency Response Corps, 2013 - 2017
Clinical Veterinarian, Armed Forces Radiobiology Research Institute (Henry M. Jackson Foundation), Bethesda, MD, 2008 - 2011
Associate Veterinarian, Mason-Dixon Equine Associates, Littlestown, PA, 2007 - 2008
Institutional Committee Activities
Member, Junior Faculty Committee, 2019 - 2021
Selection Committee Member, Chair Selection Committee, Department of Comparative Medicine, 2019 - 2019
Advisory Committee Member, Chair Selection Committee, Department of Veterinary Medicine and Surgery, 2018 - 2018
Member, Radiation Safety Committee, 2017 - Present
Member, Mobile Communications Leadership Team, 2017 - 2018
Member, Faculty Academic Review Committee, 2015 - 2018
Alternate Member, Radiation Safety Committee, 2013 - 2017
Alternate Member, Institutional Animal Care and Use Committee, 2012 - Present
Honors & Awards
| 2018 | Charles River Outstanding Clinical Veterinarian Award, Texas Branch of the American Association for Laboratory Animal Science |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Pita-Grisanti V, Velez-Bonet E, Chasser K, Hurst Z, Liette A, Vulic G, Dubay K, Lahooti A, Badi N, Ueltschi O, Gumpper-Fedus K, Hsueh HY, Lahooti I, Chavez-Tomar M, Terhorst S, Knoblaugh SE, Cao L, Huang W, Coss CC, Mace TA, Choueiry F, Hinton A, Culp S, Mitchell JM, Schmandt R, Onstad Grinsfelder M, Basen-Engquist K, Cruz-Monserrate Z. Physical Activity Decreases Inflammation and Delays the Development of Obesity-Associated Pancreatic Ductal Adenocarcinoma. Cancer Res 84(18):3058-3071, 2024. PMID: 38781455.
- Ravizzini GC, Erwin W, DePalatis L, Martiniova L, Subbiah V, Paolillo V, Mitchell J, McCoy AP, Gonzalez J, Mawlawi O. Dosimetry of a Novel 111Indium labeled Anti-P-cadherin Monoclonal Antibody (FF-21101) in Non-human Primates. Cancers 15(18):4532, 2023. PMID: None.
- Shetty G, Mitchell JM, Lam TNA, Trong T, Zhang J, Tailor RC, Peters KA, Penedo MC, Hanna C, Clark AT, Orwig KE, Meistrich ML. Postpubertal Spermatogonial Stem Cell Transplantation Restores Functional Sperm Production in Prepubertally Irradiated Rhesus Monkeys. Human Reproduction None(None):None, 2021. PMID: None.
- Shetty G, Mitchell JM, Lam TNA, Phan TT, Zhang J, Tailor RC, Peters KA, Penedo MC, Hanna CB, Clark AT, Orwig KE, Meistrich ML. Postpubertal Spermatogonial Stem Cell Transplantation Restores Functional Sperm Production in Rhesus Monkeys Irradiated Before and After Puberty. Andrology 9(5), 2021. e-Pub 2021. PMID: 33960147.
- Shetty G, Mitchell JM, Meyer JM, Wu Z, Lam TNA, Phan TT, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Hanna C, Orwig KE, Meistrich ML. Restoration of Functional Sperm Production in Irradiated Pubertal Rhesus Monkeys by Spermatogonial Stem Cell Transplantation. Andrology 8(5):1428-1441, 2020. e-Pub 2020. PMID: 32351003.
- Muñoz NM, Minhaj AA, Maldonado KL, Kingsley CV, Cortes AC, Taghavi H, Polak U, Mitchell JM, Ensor JE, Bankson JA, Rashid A, Avritscher R. Comparison of dynamic contrast-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for evaluation of the effects of sorafenib in a rat model of hepatocellular carcinoma. Magnetic Resonance Imaging 57:156-164, 2019. e-Pub 2018. PMID: 30465870.
- King GL, Sandgren DJ, Mitchell JM, Bolduc DL, Blakely WF. System for Scoring Severity of Acute Radiation Syndrome Response in Rhesus Macaques (Macaca mulatta). Comparative Medicine 68(6):1-15, 2018. e-Pub 2018. PMID: 30305197.
- Shetty G, Mitchell JM, Lam TNA, Wu Z, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Orwig KE, Meistrich ML. Donor Spermatogenesis in DeNovo Formed Seminiferous Tubules from Transplanted Testicular Cells in Rhesus Monkey Testis. Human Reproduction 33(12):2249-2255, 2018. PMID: 30358843.
- Sosa E, Chen D, Rojas EJ, Hennebold JD, Peters KA, Wu Z, Lam TN, Mitchell JM, Sukhwani M, Tailor RC, Meistrich ML, Orwig KE, Shetty G, Clark AT. Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. Nature Communications 9(1):5339, 2018. e-Pub 2018. PMID: 30559363.
- Melancon MP, Appleton Figueira T, Fuentes DT, Tian L, Qiao Y, Gu J, Gagea M, Ensor JE, Muñoz NM, Maldonado KL, Dixon K, McWatters A, Mitchell J, McArthur M, Gupta S, Tam AL. Development of an Electroporation and Nanoparticle-based Therapeutic Platform for Bone Metastases. Radiology 286(1):149-157, 2018. e-Pub 2017. PMID: 28825892.
- Mitchell J, Tinkey PT, Avritscher R, Van Pelt C, Eskandari G, Konnath George S, Xiao L, Cressman E, Morris JS, Rashid A, Kaseb AO, Amin HM, Uthamanthil R. Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs. Oncology 91(2):90-100, 2016. e-Pub 2016. PMID: 27305144.
- Mitchell J. Response to Protocol Review Scenario: Questioning is appropriate. Lab Animal 42(10):356-7, 2013. PMID: 24051637.
- Moroni M, Coolbaugh TV, Lombardini E, Mitchell JM, Moccia KD, Shelton LJ, Nagy V, Whitnall MH. Hematopoietic radiation syndrome in the Gottingen minipig. Radiation Research 176(1):89-101, 2011. e-Pub 2011. PMID: 21520996.
- Moroni M, Coolbaugh TV, Mitchell JM, Lombardini E, Moccia KD, Shelton LJ, Nagy V, Whitnall MH. Vascular access port implantation and serial blood sampling in a Gottingen minipig (Sus scrofa domestica) model of acute radiation injury. Journal of the American Association for Laboratory Animal Science 50(1):65-72, 2011. PMID: 21333166.
- Moccia KD, Olsen CH, Mitchell JM, Landauer MR. Evaluation of hydration and nutritional gels as supportive care after total-body irradiation in mice (Mus musculus). Journal of the American Association for Laboratory Animal Science 49(3):323-328, 2010. PMID: 20587164.
- Guan F, Uboh CE, Soma LR, Birks E, Chen J, Mitchell J, You Y, Rudy J, Xu F, Li X, Mbuy G. LC-MS/MS method for confirmation of recombinant human erythropoietin and darbepoetin alpha in equine plasma. Analytical Chemistry 79(12):4627-4635, 2007. e-Pub 2007. PMID: 17500535.
- Frank JA, Zywicke H, Jordan EK, Mitchell J, Lewis BK, Miller B, Bryant LH, Bulte JW. Magnetic intracellular labeling of mammalian cells by combining (FDA-approved) superparamagnetic iron oxide MR contrast agents and commonly used transfection agents. Academic Radiology 9(Supplement 2):S484-487, 2002. PMID: 12188316.
- Munoz NM, Minaj AA, Maldonado KL, Kingsley CV, Cortes AC, Taghavi H, Polak U, Mitchell JM, Ensor JE, Bankson JA, Rashid A, Bouchard RR, Avritscher R. Detection of early biological effects of multikinase inhibitor therapy in a rat model of hepatocellular carcinoma: comparison of dynamic contrast-enhanced MRI and contrast-enhanced ultrasonography. European Radiology. PMID: None.
- Ravizzini G, Erwin W, De Palatis L, Martiniova L, Subbiah V, Gonzalez Lepera C, Mitchell J, Gonzalez J, McCoy A, Macapinlac H, Tokura M, Paradiso L, Mawlawi O. Dosimetry of a Novel Anti-P-cedherin Radiotracer (FF-21101) in Non-human Primates. Nuclear Medicine and Biology. PMID: None.
Invited Articles
- Barrera A, Duran A, Mitchell J, Jensen VB. Rescue Me: Sanitation of Electronic Devices. Laboratory Animal Science Professional:60-61, 2019. PMID: None.
Other Articles
- Mitchell JM, Wafer, L N Response: Submit a new proposal. Lab Animal 44(2):54-58, 2015. PMID: None.
- Abdel-Wahab R, Shehata S, Hassan MM, Habra MA, Eskandari G, Tinkey PT, Mitchell J, Lee JS, Amin HM, Kaseb AO Type I Insulin-Like Growth Factor as a Liver Reserve Assessment Tool in Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma 2:131-142, 2015. PMID: 27508202.
Abstracts
- Pita-Grisanti V, Dubay KS, Lahooti A, Badi N, Ueltschi O, Chavez-Tomar M, Terhorst SA, Knoblaugh SE, Coss CC, Mace TA, Choueiry F, Hinton A, Mitchell JM, Basen-Engquist K, Cruz-Monserrate Z. Increased Physical Activity Delays Development of Obesity-Induced Pancreatic Ductal Adenocarcinoma in Mice and Modulates Inflammation. American Association for Cancer Research Pancreatic Cancer Conference (AACR) Virtual Special Conference, 2020. PMID: None.
Grant & Contract Support
| Title: | Next Generation Therapies for Preserving Fertility in Male Cancer Patients |
| Funding Source: | Magee Womens Research Institute and Foundation |
| Role: | Other Significant Contributor |
| Title: | Cancer Center Support (CORE) Grant |
| Funding Source: | NIH/NCI |
| Role: | Other Personnel |
| Title: | Preserving Male Fertility After Cancer Therapy - Project III - Hormone Suppression and Spermatogenic Recovery After Testicular Irradiation in Primates |
| Funding Source: | NIH/NICHD |
| Role: | Veterinarian |
| Title: | Preserving Male Fertility After Cancer Therapy - Core B: Transplantation |
| Funding Source: | NIH/NICHD |
| Role: | Veterinarian |
| Title: | 10-Selective Photothermal Ablation of HCC with Renal Clearable [64Cu] Nanodots |
| Funding Source: | Center for Advanced Biomedical Imaging - MI2 |
| Role: | Collaborator |
| Title: | Photoacoustic-based investigation of oxygen saturation as an imaging biomarker in a canine model of prostate cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| Title: | New Risk Assessment Approach to Personalize Hepatocellular Carcinoma Management |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| Title: | In Vivo Development of Interstitial-driven Photoacoustic Imaging to Investigate Hypoxia as a Biomarker for Prostate Cancer |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Title: | In Vivo Investigation of Photoacoustic and Ultrasonic Image-guided Needle Biopsy of the Prostate |
| Funding Source: | Department of Defense (DOD) |
| Role: | Collaborator |
| Title: | Evaluation of safety profile, biodistribution , pharmokinetics and immunogenicity in non-human primates of the novel radiotracer 86Y-CHX-A"-panitumumab F(ab')2 for PET imaging of HER1 expression |
| Funding Source: | Center for Advanced Biomedical Imaging - MI2 |
| Role: | Collaborator |
| Title: | Targeting the Mucus Degrading Microbiome in Acute Radiation Syndrome |
| Funding Source: | National Institutes of Health |
| Role: | Co-I |
| Title: | New Risk Assessment Approach to Personalize Hepatocellular Carcinoma Management |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
Patient Reviews
CV information above last modified November 04, 2024