J. Andrew Livingston, M.D., M.S.

Peer-Reviewed Articles

1. Mull BB, Livingston JA, Patel N, Bui T, Hunt KK, Keyomarsi K. Specific, reversible G1 arrest by UCN-01 in vivo provides cytostatic protection of normal cells against cytotoxic chemotherapy in breast cancer. Br J Cancer 122(6):812-822, 2020. e-Pub 2020. PMID: 31942030.
2. Wu CC, Beird HC, Andrew Livingston J, Advani S, Mitra A, Cao S, Reuben A, Ingram D, Wang WL, Ju Z, Hong Leung C, Lin H, Zheng Y, Roszik J, Wang W, Patel S, Benjamin RS, Somaiah N, Conley AP, Mills GB, Hwu P, Gorlick R, Lazar A, Daw NC, Lewis V, Futreal PA. Immuno-genomic landscape of osteosarcoma. Nat Commun 11(1):1008, 2020. e-Pub 2020. PMID: 32081846.
3. Bishop AJ, Bird JE, Conley AP, Roland CL, Moon BS, Satcher RL, Livingston JA, Patel S, Wang WL, Lazar AJ, Lewis VO, Lin PP, Guadagnolo BA. Extraskeletal Myxoid Chondrosarcomas: Combined Modality Therapy with both Radiation and Surgery Improves Local Control. Am J Clin Oncol 42(10):744-748, 2019. PMID: 31436747.
4. Roszik J, Khan A, Conley AP, Livingston JA, Groisberg R, Ravi V, Carmagnani Pestana R, Sen S, Subbiah V. Unique Aberrations in Intimal Sarcoma Identified by Next-Generation Sequencing as Potential Therapy Targets. Cancers (Basel) 11(9), 2019. e-Pub 2019. PMID: 31480474.
5. Zhao Q, Hu J, Mitra A, Cutrera J, Zhang W, Zhang Z, Yan J, Xia X, Mahadeo KM, Livingston JA, Gorlick R, Li S. Tumor-targeted IL-12 combined with tumor resection yields a survival-favorable immune profile. J Immunother Cancer 7(1):154, 2019. e-Pub 2019. PMID: 31208461.
6. Conley AP, Wang WL, Livingston JA, Ravi V, Tsai JW, Ali A, Ingram DR, Lowery CD, Roland CL, Somaiah N, Hwu P, Yee C, Subbiah V, Futreal A, Lazar AJ, Patel S, Roszik J. MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma. Cancers (Basel) 11(5), 2019. e-Pub 2019. PMID: 31096717.
7. Bishop AJ, Livingston JA, Araujo DM, Moon BS, Patel S, Wang WL, Lazar AJ, Roland CL, Guadagnolo BA. Extraskeletal Osteosarcomas: A Case Made for Combined Modality Local Therapy With Radiation and Surgery. Am J Clin Oncol 42(3):238-242, 2019. e-Pub 2019. PMID: 30614820.
8. Avila JC, Livingston JA, Rodriguez AM, Kirchhoff AC, Kuo YF, Kaul S. Disparities in Adolescent and Young Adult Sarcoma Survival: Analyses of the Texas Cancer Registry and the National SEER Data. J Adolesc Young Adult Oncol 7(6):681-687, 2018. e-Pub 2018. PMID: 30096005.
9. Kaul S, Russell H, Livingston JA, Kirchhoff AC, Jupiter D. Emergency Department Visits by Adolescent and Young Adult Cancer Patients Compared with Pediatric Cancer Patients in the United States. J Adolesc Young Adult Oncol 7(5):553-564, 2018. e-Pub 2018. PMID: 29924663.
10. Livingston JA, Wang WL, Tsai JW, Lazar AJ, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M, Gordon NB, Kleinerman ES. Analysis of HSP27 and the autophagy marker LC3B+ puncta following preoperative chemotherapy identifies high-risk osteosarcoma patients. Mol Cancer Ther 17(6):1315-1323, 2018. e-Pub 2018. PMID: 29592877.
11. Wagner MJ, Gopalakrishnan V, Ravi V, Livingston JA, Conley AP, Araujo D, Somaiah N, Zarzour MA, Ratan R, Wang WL, Patel SR, Lazar A, Ludwig JA, Benjamin RS. Vincristine, Ifosfamide, and Doxorubicin for Initial Treatment of Ewing Sarcoma in Adults. Oncologist 22(10):1271-1277, 2017. e-Pub 2017. PMID: 28710342.
12. Livingston JA, Bugano D, Barbo A, Lin H, Madewell JE, Wang WL, Lazar AJ, Tseng WW, Roland CL, Feig BW, Pollock R, Conley AP, Benjamin RS, Patel S, Somaiah N. Role of chemotherapy in dedifferentiated liposarcoma of the retroperitoneum: defining the benefit and challenges of the standard. Sci Rep 7(1):11836, 2017. e-Pub 2017. PMID: 28928422.
13. Santiago-O'Farrill JM, Kleinerman ES, Hollomon MG, Livingston A, Wang WL, Tsai JW, Gordon NB. Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy. Oncotarget 9(2):1602-1616, 2017. e-Pub 2017. PMID: 29416717.
14. McManus M, Kleinerman E, Yang Y, Livingston JA, Mortus J, Rivera R, Zweidler-McKay P, Schadler K. Hes4: A potential prognostic biomarker for newly diagnosed patients with high-grade osteosarcoma. Pediatr Blood Cancer 64(5), 2017. e-Pub 2016. PMID: 27786411.
15. Livingston JA, Hess KR, Naing A, Hong DS, Patel S, Benjamin RS, Ludwig JA, Conley A, Herzog CE, Anderson P, Meric-Bernstam F, Kurzrock R, Subbiah V. Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials. Oncotarget 7(39):64421-64430, 2016. e-Pub 2016. PMID: 27486883.
16. Wagner MJ, Livingston JA, Patel SR, Benjamin RS. Chemotherapy for Bone Sarcoma in Adults. J Oncol Pract 12(3):208-16, 2016. PMID: 26962160.
17. Benjamin RS, Wagner MJ, Livingston JA, Ravi V, Patel SR. Chemotherapy for bone sarcomas in adults: the MD anderson experience. Am Soc Clin Oncol Educ Book:e656-60, 2015. PMID: 25993237.
18. Lamhamedi-Cherradi SE, Santoro M, Ramammoorthy V, Menegaz BA, Bartholomeusz G, Iles LR, Amin HM, Livingston JA, Mikos AG, Ludwig JA. 3D tissue-engineered model of Ewing's sarcoma. Adv Drug Deliv Rev 79-80:155-71, 2014. e-Pub 2014. PMID: 25109853.
19. Kanda J, Chiou LW, Szabolcs P, Sempowski GD, Rizzieri DA, Long GD, Sullivan KM, Gasparetto C, Chute JP, Morris A, McPherson J, Hale J, Livingston JA, Broadwater G, Niedzwiecki D, Chao NJ, Horwitz ME. Immune recovery in adult patients after myeloablative dual umbilical cord blood, matched sibling, and matched unrelated donor hematopoietic cell transplantation. Biol Blood Marrow Transplant 18(11):1664-1676.e1, 2012. e-Pub 2012. PMID: 22698485.
20. Subbiah V, Bupathi M, Kato S, Livingston, A, Slopis, J, Anderson, P, Hong, DS. Clinical next-generation sequencing reveals aggressive cancer biology in adolescent and young adult patients. Oncoscience. e-Pub 2015. PMID: 26328274.
21. Gilchrist SC, Roth M, Livingston JA, Hildebrandt MAT, Kleinerman ES, Banchs J. Short-Term Changes in Cardiac Function in Osteosarcoma Patients Receiving Anthracyclines. J Adolesc Young Adult Oncol. e-Pub 2019. PMID: 30794081.

Invited Articles

1. El Beaino M, Roszik J, Livingston JA, Wang WL, Lazar AJ, Amini B, Subbiah V, Lewis V, Conley AP. Mesenchymal chondrosarcoma: A review with emphasis on its fusion-driven biology. Curr Oncol Rep 20(5):37, 2018. e-Pub 2018. PMID: 29582189.
2. Roszik J, Wang WL, Livingston JA, Roland CL, Ravi V, Yee C, Hwu P, Futreal A, Lazar AJ, Patel SR, Conley AP. Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes. Clin Sarcoma Res 7:11, 2017. e-Pub 2017. PMID: 28630682.

Editorials

1. Livingston JA. Improving Outcomes for Adolescents and Young Adults With Sarcoma: A Focus on Cancer Care Delivery. J Oncol Pract 15(5):253-254, 2019. PMID: 31075216.

Abstracts

1. Wang WL, Lazar A, Wu CC, Beird H, Ingram D, Khan S, Wani K, Daw N, Futreal A, Livingston JA. DNA Damage Response Deficiency in Osteosarcoma. CTOS Annual Meeting, 2019.
2. McCall D, Roszik J, Cuglievan B, Ludwig J, Zarzour M, Gill J, Livingston JA, Subbiah V. EWS-Fusion Partners in Sarcoma as Revealed by "Real World" Genomic Sequencing: Clinical Implications. CTOS Annual Meeting, 2019.
3. D'Angelo S, Conley A, Kelly C, Dickson M, Gounder M, Chi P, Livingston JA, Patel S, Adamson T, Kiesler H, Hwang S, Tap W. Pilot study of NKTR214 and nivolumab in patients with sarcomas. ASCO Annual Meeting, 2019.
4. Amaria R, Bernatchez C, Forget MA, Haymaker C, Conley A, Livingston JA, Varadachary G, Java M, Mitra A, Tzeng C, Hinchiff E, Bayer V, Hilton T, Celestiino J, Rangel K, Yuan Y, Lu K, Hwu P, Jazaeri A. Adoptive transfer of tumor-infiltrating lymphocytes in patients with sarcomas, ovarian, and pancreatic cancers. ASCO Annual Meeting, 2019.
5. Livingston JA, Posey K, Wang WL et al. Chemotherapy in the treatment of undifferentiated high grade pleomorphic sarcoma of bone. CTOS Annual Meeting, 2018.
6. Livingston JA, Beird HC, Wu C, Cao, Advani, Ingram, Wang WL, Lazar AJ, Leung, Lin, Reuben, Roszik, Wang W, Patel S, Benjamin R, Gorlick R, Lewis V, Futreal PA, Daw N. Parallel genomic and immune profiling of relapsed and metastatic osteosarcoma to reveal bases of low immunogenicity. ASCO Annual Meeting, 2018.
7. Wu C, Beird HC, Livingston JA, Cao, Advani, Ingram, Wang WL, Lazar AJ, Leung, Lin, Reuben, Roszik, Wang W, Patel S, Benjamin R, Gorlick R, Lewis V, Daw N, Futreal PA. Genome and transcriptome profiling of relapsed and metastatic osteosarcoma. ASCO Annual Meeting, 2018.
8. Livingston JA, Posey K, Subbiah VS, Daw N, Somaiah N, Ravi V, Patel S, Benjamin RS, Wang WL, Lazar AJ, Broaddus R, Meric-Bernstam F, Shaw K, Roszik J, Conley AP. Analysis of osteosarcoma subtypes by clinical genomic testing to identify clinically actionable alterations. ASCO Annual Meeting, 2017.
9. Avila JC, Livingston JA, Rodriguez A, Kirchoff AC, Kue TF, Kaul S. Disparities in Survival Among Adolescent and Young Adult Patients with Sarcomas in Texas. AACR Annual Meeting 2017, 2017.
10. Roszik J, Conley AP, Livingston JA, Ravi V, Lazar A. Next-generation sequencing identifies immunotherapy targets in soft tissue sarcoma. Connective Tissue Oncology Society Annual Meeting, 2017.
11. Conley AP, Livingston JA et al. Assessment of next-generation sequencing (NGS) for patients with chondrosarcoma. CTOS Annual Meeting, 2017.
12. Ratan R, Livingston JA et al. CIC rearranged sarcomas. CTOS Annual Meeting, 2017.
13. Subbiah V, Conley A, Livingston JA, Lazar A, Meric-Bernstam F, Futreal A, Roszik J. Picking Antibody-drug conjugate targets for drug development for sarcoma: Diving deeper into TCGA. CTOS Annual Meeting, 2017.
14. Livingston JA, Tsai J, Advani S, Daw N, Lazar A, Conley AP, Wang WL. Expression and clinical correlations of PRAME in osteosarcoma. Connective Tissue Oncology Society Annual Meeting, 2016.
15. Wagner M, Livingston JA, Benjamin RS, et al. Vincristine, doxorubicin, and ifosfamide for the initial treatment of Ewing’s sarcoma in adults. Connective Tissue Oncology Society Annual Meeting, 2015.
16. Livingston JA, Wagner M, Benjamin RS et al.. Tailored post-operative therapy in adult osteosarcoma improves outcomes in patients with poor necrosis: 30 years of treatment at MD Anderson. Connective Tissue Oncology Society Annual Meeting, 2015.
17. Livingston JA, Ofarrill-Santiago J, Gordon N, Kleinerman ES. Heat shock protein 27 (HSP27) as a predictor of autophagic fate in chemotherapy-induced autophagy in osteosarcoma. Connective Tissue Oncology Society Annual Meeting, 2015.
18. Livingston JA, Somaiah N, et al. Assessing chemotherapy benefit in well-differentiated and de-differentiated retroperitoneal liposarcoma. Connective Tissue Oncology Society Annual Meeting, 2014.
19. Gomes D, Livingston JA, Somaiah N et al. Defining the chemotherapy (CT) response in well-differentiated (WD) and dedifferentiated (DD) liposarcomas (LPS) of the retroperitoneum (RP): a tertiary referral cancer center experience. ASCO Annual Meeting, 2014.
20. Livingston JA, V Subbiah, et al. Eliciting early-response signals from first-in-human clinical trials and validation of prognostic scores in aggressive biology bone cancers: The MD Anderson experience. ASCO Annual Meeting 2014, 2014.
21. Bupathi M, Livingston JA, Subbiah VS et al. Clinical Next Generation Sequencing of Adolescents and Young Adult (AYA) patients with Cancer Reveals Aggressive Biology: A Preliminary Report. AACR Annual Meeting 2014, 2014.
22. Sharma S, Livingston JA, Hatch S. Higher pelvic/para-aortic lymph node metastasis probability in cervical cancer patients with unexplained leukocytosis: a retrospective review. Western Association of Gynecologic Oncologists Annual Meeting 2014, 2014.
23. Livingston JA, Dave S, Rao AV. Evaluating oncogenic pathway dysregulation in adolescents and young adults with acute myeloid leukemia. ASCO Annual Meeting, 2013.

Book Chapters

1. Wu CC, Livingston JA. Genomics and the Immune Landscape of Osteosarcoma. In: Adv Exp Med Biol. Springer, 21-36, 2020.
2. Livingston JA, Conley AP, Ravi V, Patel S. Soft-Tissue and Bone Sarcomas. In: The MD Anderson Manual of Medical Oncology. 3rd. McGraw Hill Medical: New York, 2016.
3. Chin M, Livingston JA. Osteosarcoma. In: Sarcomas: Evidence-Based Diagnosis and Management. Springer.