
Jun Li, Ph.D.
Department of Bioinformatics and Computational Biology, Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Bioinformatics and Computational Biology, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Assistant Professor, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2013 | Chinese Academy of Sciences, Shanghai, CN, Computational Biology, Ph.D |
2008 | Wuhan University, Wuhan, CN, Mathematics, BS |
Postgraduate Training
2013-2018 | Postdoctoral, Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas |
Honors & Awards
2023 | MDACC UT SPORE in Lung Cancer CEP award, MD Anderson Cancer Center |
2019 | Robert M. Chamberlain Distinguished Mentor Award Finalist, The University of Texas MD Anderson Cancer Center |
2016 | The Ben F. Love Fellowship in Innovative Cancer Therapies, The University of Texas MD Anderson Cancer Center |
2012 | Huirui Fellowship, Shanghai Institutes for Biological Sciences |
2012 | Trainee Research Day GSTPC Poster Contest Finalist, The University of Texas MD Anderson Cancer Center |
2010 | Outstanding Student Scholarship, CAS-MPG Partner Institute for Computational Biology |
2005 | Outstanding Student Scholarship, Wuhan University |
Selected Publications
Peer-Reviewed Articles
- Li J, Liu W, Kim H, Mojumdar K, Zhou Z, Ju Z, Kumar SV, Ng PK, Davies MA, Lu Y, Akbani R, Mills GB, Liang H. A protein expression atlas on tissue samples and cell lines from cancer patients provides insights into tumor heterogeneity and dependencies. Nature Cancer, 2024. e-Pub 2024. PMID: 39227745.
- Hahn AW, Menk AV, Rivadeneira DB, Augustin RC, Xu M, Li J, Wu X, Mishra AK, Gide TN, Quek C, Zang Y, Spencer CN, Menzies AM, Daniel CR, Hudgens CW, Nowicki T, Haydu LE, Khan MAW, Gopalakrishnan V, Burton EM, Malke J, Simon JM, Bernatchez C, Putluri N, Woodman SE, Vashisht Gopal YN, Guerrieri R, Fischer GM, Wang J, Wani KM, Thompson JF, Lee JE, Hwu P, Ajami N, Gershenwald JE, Long GV, Scolyer RA, Tetzlaff MT, Lazar AJ, Schadendorf D, Wargo JA, Kirkwood JM, DeBerardinis RJ, Liang H, Futreal A, Zhang J, Wilmott JS, Peng W, Davies MA, Delgoffe GM, Najjar YG, McQuade JL. Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma. Clinical Cancer Research 29(1):154-164, 2023. e-Pub 2023. PMID: 36166093.
- Li J*, Lu H*, Ng PK*, Pantazi A*, Ip CKM, Jeong KJ, Amador B, Tran R, Tsang YH, Yang L, Song X, Dogruluk T, Ren X, Hadjipanayis A, Bristow CA, Lee S, Kucherlapati M, Parfenov M, Tang J, Seth S, Mahadeshwar HS, Mojumdar K, Zeng D, Zhang J, Protopopov A, Seidman JG, Creighton CJ, Lu Y, Sahni N, Shaw KR, Meric-Bernstam F, Futreal A, Chin L, Scott KL, Kucherlapati R, Mills GB, Liang H. A functional genomic approach to actionable gene fusions for precision oncology. Science Advances 8(6):eabm2382, 2022. e-Pub 2022. PMID: 35138907.
- Li J, Chen H, Wang Y, Chen MM, Liang H. Next-Generation Analytics for Omics Data. Cancer Cell 39(1):3-6, 2021. e-Pub 2021. PMID: 32976776.
- Sieverling, L, Hong, C, Koser, S, Ginsbach, P, Kleinheinz, K, Hutter, B, Braun, DM, Cortés-Ciriano, I, Xi, R, Kabbe, R, Park, PJ, Eils, R, Schlesner, M, Akdemir, KC, Alvarez, EG, Chen, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Genomic footprints of activated telomere maintenance mechanisms in cancer. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024817.
- Paczkowska, M, Barenboim, J, Sintupisut, N, Fox, NS, Zhu, H, Abd-Rabbo, D, Mee, MW, Boutros, PC, Abascal, F, Amin, S, Bader, GD, Beroukhim, R, Bertl, J, Boroevich, KA, Chakravarty, D, Chen, K, Park, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Integrative pathway enrichment analysis of multivariate omics data. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024846.
- Cmero, M, Yuan, K, Ong, CS, Schröder, J, Adams, DJ, Anur, P, Beroukhim, R, Boutros, PC, Bowtell, DD, Campbell, PJ, Cao, S, Christie, EL, Cun, Y, Dawson, KJ, Demeulemeester, J, Eils, R, Fan, Y, Van Loo, P, Wang, W, Zhu, H, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Chakravarty, D, Chen, K, Chen, Y, Czerniak, BA, El-Naggar, AK, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Wang, L, Weinstein, JN, Yuan, Y. Inferring structural variant cancer cell fraction. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024845.
- Jiao, W, Atwal, G, Polak, P, Karlic, R, Cuppen, E, Al-Shahrour, F, Atwal, G, Bailey, PJ, Biankin, AV, Boutros, PC, Campbell, PJ, Chang, DK, Cooke, SL, Lazar, A, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024849.
- Li, CH, Prokopec, SD, Sun, RX, Yousif, F, Schmitz, N, Al-Shahrour, F, Atwal, G, Bailey, PJ, Biankin, AV, Boutros, PC, Campbell, PJ, Eils, R, Myklebost, O, Borresen-Dale, A, Plass, C, Akbani, R, Akdemir, KC, Aldape, KD, Broaddus, R, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Sex differences in oncogenic mutational processes. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32859912.
- Bailey, M, Meyerson, WU, Dursi, LJ, Wang, LB, Dong, G, Liang, WW, Weerasinghe, A, Li, S, Kelso, S, Akbani, R, Anur, P, Bailey, MH, Buchanan, A, Chiotti, K, Covington, KR, Creason, A, Ding, L, Ellrott, K, Huse, J, Wang, W, Weinstein, JN, Chen, K, Chong, Z, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Park, K, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Yuan, Y, Zhu, H. Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32958763.
- Rubanova, Y, Shi, R, Harrigan, CF, Li, R, Wintersinger, J, Sahin, N, Deshwar, AG, Dentro, SC, Leshchiner, I, Gerstung, M, Jolly, C, Haase, K, Tarabichi, M, Wintersinger, J, Cao, S, Eils, R, Fan, Y, Zhu, H, Wang, W, Van Loo, P, Akbani, R, Aldape, KD, Borresen-Dale, A, Chakravarty, D, Chen, K, Chen, Y, Czerniak, BA, El-Naggar, AK, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Wang, L, Weinstein, JN, Yuan, Y. Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024834.
- Shuai, S, Abascal, F, Amin, S, Bader, GD, Bandopadhayay, P, Barenboim, J, Beroukhim, R, Bertl, J, Boroevich, KA, Brunak, S, Campbell, PJ, Carlevaro-Fita, J, Chakravarty, D, Chan, CY, Chen, K, Choi, JK, Deu-Pons, J, Dhingra, P, Park, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Combined burden and functional impact tests for cancer driver discovery using DriverPower. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024818.
- Zhang, Y, Chen, F, Fonseca, NA, He, Y, Fujita, M, Nakagawa, H, Zhang, Z, Brazma, A, Amin, SB, Awadalla, P, Bailey, PJ, Brazma, A, Brooks, AN, Calabrese, C, Chateigner, A, Cortés-Ciriano, I, Akdemir, KC, Chen, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024823.
- Reyna, MA, Haan, D, Paczkowska, M, Verbeke, LP, Vazquez, M, Kahraman, A, Pulido-Tamayo, S, Barenboim, J, Wadi, L, Dhingra, P, Shrestha, R, Getz, G, Lawrence, MS, Pedersen, JS, Rubin, MA, Chakravarty, D, Chen, K, Park, K, Akbani, R, Aldape, KD, Borresen-Dale, A, Cao, S, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Pathway and network analysis of more than 2500 whole cancer genomes. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024854.
- Zhao W*, Li J*, Chen MM, Luo Y, Ju Z, Nesser NK, Johnson-Camacho K, Boniface CT, Lawrence Y, Pande NT, Davies MA, Herlyn M, Muranen T, Zervantonakis IK, von Euw E, Schultz A, Kumar SV, Korkut A, Spellman PT, Akbani R, Slamon DJ, Gray JW, Brugge JS, Lu Y, Mills GB, Liang H. Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines. Cancer Cell 38(6):829-843.e4, 2020. e-Pub 2020. PMID: 33157050.
- Chen MM, Li J, Mills GB, Liang H. Predicting Cancer Cell Line Dependencies from the Protein Expression Data of Reverse-Phase Protein Arrays. JCO Clinical Cancer Informatics 4:357-366, 2020. e-Pub 2020. PMID: 32330068.
- Yuan Y, Ju YS, Kim Y, Li J, Wang Y, Yoon CJ, Yang Y, Martincorena I, Creighton CJ, Weinstein JN, Xu Y, Han L, Kim HL, Nakagawa H, Park K, Campbell PJ, Liang H, Consortium P. Comprehensive Molecular Characterization of Mitochondrial Genomes in Human Cancers. Nature Genetics 52(3):342-352, 2020. e-Pub 2020. PMID: 32024997.
- Campbell, PJ, Getz, G, Korbel, JO, Stuart, JM, Jennings, JL, Stein, L, Perry, MD, Nahal-Bose, HK, Ouellette, BF, Li, CH, Rheinbay, E, Nielsen, GP, Lazar, A, Wang, W, Van Loo, P, Weinstein, JN, Fan, Y, Chen, K, Chong, Z, Eils, R, Chakravarty, D, Park, K, Plass, C, Akdemir, KC, Cao, S, Zhu, H, Chen, Y, Han, L, Li, J, Yuan, Y, Liang, H, Su, X, Lichter, P, Borresen-Dale, A, Krishnamurthy, S, Thompson, A, Ueno, NT, von Kalle, C, Futreal, A, Akbani, R, Aldape, KD, Broaddus, R, Czerniak, BA, El-Naggar, AK, Gershenwald, JE, Huse, J, Lu, Y, Mills, GB, Sood, AK, Wang, L. Pan-cancer analysis of whole genomes. Nature 578(7793):82-93, 2020. e-Pub 2020. PMID: 32025007.
- Chen H, Li J, Wang Y, Ng PK, Tsang YH, Shaw KR, Mills GB, Liang H. Comprehensive assessment of computational algorithms in predicting cancer driver mutations. Genome Biology 21(1):43, 2020. e-Pub 2020. PMID: 32079540.
- Chen MM, Li J, Wang Y, Akbani R, Lu Y, Mills GB, Liang H. TCPA v3.0: An Integrative Platform to Explore the Pan-cancer Analysis of Functional Proteomic Data. Molecular & Cellular Proteomics 18(8 suppl 1):S15-S25, 2019. e-Pub 2019. PMID: 31201206.
- Zhang H, Wang Y, Li J, Chen H, He X, Zhang H, Liang H, Lu J. Biosynthetic energy cost for amino acids decreases in cancer evolution. Nature Communications 9(1), 2018. e-Pub 2018. PMID: 30297703.
- Korkut A, Zaidi S, Kanchi RS, Rao S, Gough NR, Schultz A, Li X, Lorenzi PL, Berger AC, Robertson G, Kwong LN, Datto M, Roszik J, Ling S, Ravikumar V, Manyam G, Rao A, Shelley S, Liu Y, Ju Z, Hansel D, de Velasco G, Pennathur A, Andersen JB, O'Rourke CJ, Ohshiro K, Jogunoori W, Nguyen BN, Li S, Osmanbeyoglu HU, Ajani JA, Mani SA, Houseman A, Wiznerowicz M, Chen J, Gu S, Ma W, Zhang J, Tong P, Cherniack AD, Deng C, Resar L, CGARN (including Li J), Weinstein JN, Mishra L, Akbani R. A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily. Cell Systems 7(4):422-437.e7, 2018. e-Pub 2018. PMID: 30268436.
- Wang Y, Xu X, Maglic D, Dill MT, Mojumdar K, Ng PK, Jeong KJ, Tsang YH, Moreno D, Bhavana VH, Peng X, Ge Z, Chen H, Li J, Chen Z, Zhang H, Han L, Du D, Creighton CJ, Mills GB, Research Network CGA, Camargo F, Liang H. Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer. Cell Reports 25(5):1304-1317.e5, 2018. e-Pub 2018. PMID: 30380420.
- Kahles A, Lehmann KV, Toussaint NC, Hüser M, Stark SG, Sachsenberg T, Stegle O, Kohlbacher O, Sander C, CGARN (including Li J), Rätsch G. Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients. Cancer Cell 34(2):211-224.e6, 2018. e-Pub 2018. PMID: 30078747.
- Zhao W, Li J, Akbani R, Liang H, Mills GB. Credentialing Individual Samples for Proteogenomic Analysis. Molecular & Cellular Proteomics 17(8):1515-1530, 2018. e-Pub 2018. PMID: 29716986.
- Taylor, A, Shih, J, Ha, G, Gao, GF, Zhang, X, Berger, AC, Schumacher, SE, Wang, C, Lazar, A, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer cell 33(4):676-689.e3, 2018. e-Pub 2018. PMID: 29622463.
- Wang, Z, Yang, B, Zhang, M, Guo, W, Wu, Z, Wang, Y, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer cell 33(4):706-720.e9, 2018. e-Pub 2018. PMID: 29622465.
- Liu, Y, Sethi, NS, Hinoue, T, Schneider, BG, Cherniack, AD, Sanchez-Vega, F, Seoane, JA, Farshidfar, F, Akbani, R, Kanchi, RS, Mishra, L, Lazar, A, Wistuba, II, Liu, Y, Zhang, W, Broom, BM, Ju, Z, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer cell 33(4):721-735.e8, 2018. e-Pub 2018. PMID: 29622466.
- Bailey, M, Tokheim, C, Porta-Pardo, E, Sengupta, S, Wang, Z, Liang, H, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Chen, K. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell 173(2):371-385.e18, 2018. e-Pub 2018. PMID: 29625053.
- Chen, H, Li, C, Peng, X, Zhou, Z, Weinstein, JN, Caesar-Johnson, SJ, Demchok, JA, Felau, I, Kasapi, M, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Liang, H. A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. Cell 173(2):386-399.e12, 2018. e-Pub 2018. PMID: 29625054.
- Malta, TM, Sokolov, A, Gentles, AJ, Burzykowski, T, Poisson, LM, Weinstein, JN, Kaminska, B, Huelsken, J, Mishra, L, Lazar, A, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell 173(2):338-354.e15, 2018. e-Pub 2018. PMID: 29625051.
- Ding, L, Bailey, M, Porta-Pardo, E, Thorsson, V, Colaprico, A, Bertrand, D, Akbani, R, Mills, GB, Lazar, A, Liu, Y, Zhang, W, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell 173(2):305-320.e10, 2018. e-Pub 2018. PMID: 29625049.
- Huang, KL, Mashl, RJ, Wu, Y, Ritter, DI, Wang, J, Oh, C, Paczkowska, M, Kim, T, Logothetis, CJ, Wistuba, II, Chen, K, Liu, Y, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, von Deimling, A, Meric-Bernstam, F. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell 173(2):355-370.e14, 2018. e-Pub 2018. PMID: 29625052.
- Hoadley, KA, Yau, C, Hinoue, T, Wolf, D, Lazar, A, Drill, E, Shen, R, Taylor, A, Cherniack, AD, Thorsson, V, Akbani, R, Bowlby, R, Wong, C, Wistuba, II, Liu, Y, Zhang, W, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell 173(2):291-304.e6, 2018. e-Pub 2018. PMID: 29625048.
- Liu, J, Lichtenberg, TM, Hoadley, KA, Poisson, LM, Lazar, A, Cherniack, AD, Kovatich, AJ, Scapulatempo, CN, Wistuba, II, Carvalho, AL, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, von Deimling, A. An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell 173(2):400-416.e11, 2018. e-Pub 2018. PMID: 29625055.
- Sanchez-Vega, F, Mina, M, Armenia, J, Chatila, WK, Luna, A, La, KC, Liang, H, Lazar, A, Kwong, L, Frederick, MJ, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell 173(2):321-337.e10, 2018. e-Pub 2018. PMID: 29625050.
- Way, GP, Sanchez-Vega, F, La, KC, Armenia, J, Chatila, WK, Luna, A, Wistuba, II, von Deimling, A, Carvalho, AL, Scapulatempo, CN, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A. Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Reports 23(1):172-180.e3, 2018. e-Pub 2018. PMID: 29617658.
- Knijnenburg, T, Wang, L, Zimmermann, MT, Chambwe, N, Gao, GF, Cherniack, AD, Liu, Y, Akbani, R, Weinstein, JN, Li, L, Mills, GB, Zhang, W, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Uppore Kukkillaya, AR, Zhang, J, Liu, X, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports 23(1):239-254.e6, 2018. e-Pub 2018. PMID: 29617664.
- Jayasinghe, R, Cao, S, Gao, Q, Wendl, MC, Vo, NS, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Chen, K. Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Reports 23(1):270-281.e3, 2018. e-Pub 2018. PMID: 29617666.
- Gao, Q, Liang, WW, Foltz, SM, Mutharasu, G, Jayasinghe, R, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Chen, K. Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Reports 23(1):227-238.e3, 2018. e-Pub 2018. PMID: 29617662.
- Seiler, M, Peng, S, Agrawal, AA, Palacino, J, Teng, T, Zhu, P, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types. Cell Reports 23(1):282-296.e4, 2018. e-Pub 2018. PMID: 29617667.
- Campbell, JD, Yau, C, Liu, Y, Akbani, R, Byers, LA, Kanchi, RS, Gay, CM, Diao, L, Ma, W, Lazar, A, Flores, ER, Tsai, KY, Wistuba, II, Zhang, W, Broom, BM, Ju, Z, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Pickering, CR. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports 23(1):194-212.e6, 2018. e-Pub 2018. PMID: 29617660.
- Saltz, JH, Gupta, R, Hou, L, Kurc, T, Singh, PK, Nguyen, V, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Uppore Kukkillaya, AR. Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Reports 23(1):181-193.e7, 2018. e-Pub 2018. PMID: 29617659.
- Chiu, HS, Somvanshi, S, Patel, E, Chen, TW, Singh, VP, Zorman, B, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Sood, AK. Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Reports 23(1):297-312.e12, 2018. e-Pub 2018. PMID: 29617668.
- Ricketts, CJ, de Cubas, AA, Fan, H, Smith, CC, Lang, M, Reznik, E, Akbani, R, Kanchi, RS, Mills, GB, Tamboli, P, Liu, Y, Zhang, W, Broom, BM, Ju, Z, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports 23(1):313-326.e5, 2018. e-Pub 2018. PMID: 29617669.
- Peng X, Chen Z, Farshidfar F, Xu X, Lorenzi PL, Wang Y, Cheng F, Tan L, Mojumdar K, Du D, Ge Z, Li J, Thomas GV, Birsoy K, Liu L, Zhang H, Zhao Z, Marchand C, Weinstein JN, Research Network CGA, Bathe OF, Liang H. Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. Cell Reports 23(1):255-269.e4, 2018. e-Pub 2018. PMID: 29617665.
- Berger AC, Korkut A, Kanchi RS, Hegde AM, Lenoir W, Liu W, Liu Y, Fan H, Shen H, Ravikumar V, Rao A, Schultz A, Li X, Sumazin P, Williams C, Mestdagh P, Gunaratne PH, Yau C, Bowlby R, Robertson AG, Tiezzi DG, Wang C, Cherniack AD, Godwin AK, Kuderer NM, Rader JS, Zuna RE, Sood AK, Lazar AJ, Ojesina AI, Adebamowo C, Adebamowo SN, Baggerly KA, Chen TW, Chiu HS, Lefever S, Liu L, MacKenzie K, Orsulic S, Roszik J, Shelley CS, Song Q, Vellano CP, Wentzensen N, CGARN (including Li J), Weinstein JN, Mills GB, Levine DA, Akbani R. A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell 33(4):690-705.e9, 2018. e-Pub 2018. PMID: 29622464.
- Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H, Research Network CGA, Piwnica-Worms H, Ma L, Liang H. Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Reports 23(1):213-226.e3, 2018. e-Pub 2018. PMID: 29617661.
- Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, CGARN (including Li J), Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I. The Immune Landscape of Cancer. Immunity 48(4):812-830.e14, 2018. e-Pub 2018. PMID: 29628290.
- Schaub, FX, Dhankani, V, Berger, AC, Trivedi, M, Richardson, AB, Shaw, R, Zhao, W, Zhang, X, Liu, Y, Wistuba, II, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, von Deimling, A. Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems 6(3):282-300.e2, 2018. e-Pub 2018. PMID: 29596783.
- Ellrott, K, Bailey, M, Saksena, G, Covington, KR, Kandoth, C, Stewart, C, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Systems 6(3):271-281.e7, 2018. e-Pub 2018. PMID: 29596782.
- Ng PK*, Li J*, Jeong KJ*, Shao S, Chen H, Tsang YH, Sengupta S, Wang Z, Bhavana VH, Tran R, Soewito S, Minussi DC, Moreno D, Kong K, Dogruluk T, Lu H, Gao J, Tokheim C, Zhou DC, Johnson AM, Zeng J, Ip CKM, Ju Z, Wester M, Yu S, Li Y, Vellano CP, Schultz N, Karchin R, Ding L, Lu Y, Cheung LWT, Chen K, Shaw KR, Meric-Bernstam F, Scott KL, Yi S, Sahni N, Liang H, Mills GB. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell 33(3):450-462.e10, 2018. e-Pub 2018. PMID: 29533785.
- Li J, Akbani R, Zhao W, Lu Y, Weinstein JN, Mills GB, Liang H. Explore, Visualize, and Analyze Functional Cancer Proteomic Data Using the Cancer Proteome Atlas. Cancer Research 77(21):e51-e54, 2017. e-Pub 2017. PMID: 29092939.
- Deng J, Chen H, Zhou D, Zhang J, Chen Y, Liu Q, Ai D, Zhu H, Chu L, Ren W, Zhang X, Xia Y, Sun M, Zhang H, Li J, Peng X, Li L, Han L, Lin H, Cai X, Xiang J, Chen S, Sun Y, Zhang Y, Zhang J, Chen H, Zhang S, Zhao Y, Liu Y, Liang H, Zhao K. Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations. Nature Communications 8(1):1533, 2017. e-Pub 2017. PMID: 29142225.
- Wang Y, Xu X, Yu S, Jeong KJ, Zhou Z, Han L, Tsang YH, Li J, Chen H, Mangala LS, Yuan Y, Eterovic AK, Lu Y, Sood AK, Scott KL, Mills GB, Liang H. Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Genome Research 27(7):1112-1125, 2017. e-Pub 2017. PMID: 28411194.
- Lin A, Hu Q, Li C, Xing Z, Ma G, Wang C, Li J, Ye Y, Yao J, Liang K, Wang S, Park PK, Marks JR, Zhou Y, Zhou J, Hung MC, Liang H, Hu Z, Shen H, Hawke DH, Han L, Zhou Y, Lin C, Yang L. The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors. Nature Cell Biology 19(3):238-251, 2017. e-Pub 2017. PMID: 28218907.
- Li J, Zhao W, Akbani R, Liu W, Ju Z, Ling S, Vellano CP, Roebuck P, Yu Q, Eterovic AK, Byers LA, Davies MA, Deng W, Gopal YN, Chen G, von Euw EM, Slamon D, Conklin D, Heymach JV, Gazdar AF, Minna JD, Myers JN, Lu Y, Mills GB, Liang H. Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays. Cancer Cell 31(2):225-239, 2017. e-Pub 2017. PMID: 28196595.
- Xu-Monette, Z, Deng, Q, Manyam, GC, Tzankov, A, Li, L, Xia, Y, Wang, XX, Zou, D, Visco, C, Dybkær, K, Li, J, Zhang, L, Liang, H, Montes-Moreno, S, Chiu, A, Orazi, A, Zu, Y, Bhagat, G, Richards, KL, Hsi, ED, Choi, WW, Van Krieken, JH, Huh, J, Ponzoni, M, Ferreri, AJ, Parsons, BM, Møller, MB, Wang, S, Miranda, R, Piris, MA, Winter, JN, Medeiros, LJ, Li, Y, Young, KH. Clinical and biologic significance of MYC genetic mutations in de novo diffuse large B-cell lymphoma. Clinical Cancer Research 22(14):3593-3605, 2016. e-Pub 2016. PMID: 26927665.
- Yuan Y, Liu L, Chen H, Wang Y, Xu Y, Mao H, Li J, Mills GB, Shu Y, Li L, Liang H. Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients. Cancer Cell 29(5):711-722, 2016. e-Pub 2016. PMID: 27165743.
- Research Network CGA, Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, Rathmell WK, Brooks AN, Hoadley KA, Robertson AG, Brooks D, Bowlby R, Sadeghi S, Shen H, Weisenberger DJ, Bootwalla M, Baylin SB, Laird PW, Cherniack AD, Saksena G, Haake S, Li J, Liang H, Lu Y, Mills GB, Akbani R, Leiserson MD, Raphael BJ, Anur P, Bottaro D, Albiges L, Barnabas N, Choueiri TK, Czerniak B, Godwin AK, Hakimi AA, Ho TH, Hsieh J, Ittmann M, Kim WY, Krishnan B, Merino MJ, Mills Shaw KR, Reuter VE, Reznik E, Shelley CS, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Tickoo S, Burnett K, Crain D, Gardner J, Lau K, Mallery D, Morris S, Paulauskis JD, Penny RJ, Shelton C, Shelton WT, Sherman M, Thompson E, Yena P, Avedon MT, Bowen J, Gastier-Foster JM, Gerken M, Leraas KM, Lichtenberg TM, Ramirez NC, Santos T, Wise L, Zmuda E, Demchok JA, Felau I, Hutter CM, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Zhang J, Ayala B, Baboud J, Chudamani S, Liu J, Lolla L, Naresh R, Pihl T, Sun Q, Wan Y, Wu Y, Ally A, Balasundaram M, Balu S, Beroukhim R, Bodenheimer T, Buhay C, Butterfield YS, Carlsen R, Carter SL, Chao H, Chuah E, Clarke A, Covington KR, Dahdouli M, Dewal N, Dhalla N, Doddapaneni HV, Drummond JA, Gabriel SB, Gibbs RA, Guin R, Hale W, Hawes A, Hayes DN, Holt RA, Hoyle AP, Jefferys SR, Jones SJ, Jones CD, Kalra D, Kovar C, Lewis L, Li J, Ma Y, Marra MA, Mayo M, Meng S, Meyerson M, Mieczkowski PA, Moore RA, Morton D, Mose LE, Mungall AJ, Muzny D, Parker JS, Perou CM, Roach J, Schein JE, Schumacher SE, Shi Y, Simons JV, Sipahimalani P, Skelly T, Soloway MG, Sougnez C, Tam A, Tan D, Thiessen N, Veluvolu U, Wang M, Wilkerson MD, Wong T, Wu J, Xi L, Zhou J, Bedford J, Chen F, Fu Y, Gerstein M, Haussler D, Kasaian K, Lai P, Ling S, Radenbaugh A, Van Den Berg D, Weinstein JN, Zhu J, Albert M, Alexopoulou I, Andersen JJ, et al. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. The New England Journal of Medicine 374(2):135-45, 2016. e-Pub 2016. PMID: 26536169.
- Han L, Diao L, Yu S, Xu X, Li J, Zhang R, Yang Y, Werner HMJ, Eterovic AK, Yuan Y, Li J, Nair N, Minelli R, Tsang YH, Cheung LWT, Jeong KJ, Roszik J, Ju Z, Woodman SE, Lu Y, Scott KL, Li JB, Mills GB, Liang H. The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers. Cancer Cell 28(4):515-528, 2015. e-Pub 2015. PMID: 26439496.
- Li J, Han L, Roebuck P, Diao L, Liu L, Yuan Y, Weinstein JN, Liang H. TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer. Cancer Research 75(18):3728-37, 2015. e-Pub 2015. PMID: 26208906.
- Bansal M, Yang J, Karan C, Menden MP, Costello JC, Tang H, Xiao G, Li Y, Allen J, Zhong R, Chen B, Kim M, Wang T, Heiser LM, Realubit R, Mattioli M, Alvarez MJ, Shen Y, NDC (including Li J), Gallahan D, Singer D, Saez-Rodriguez J, Xie Y, Stolovitzky G, Califano A, Community N. A community computational challenge to predict the activity of pairs of compounds. Nature Biotechnology 32(12):1213-22, 2014. e-Pub 2014. PMID: 25419740.
- Costello JC, Heiser LM, Georgii E, Gönen M, Menden MP, Wang NJ, Bansal M, Ammad-ud-din M, Hintsanen P, Khan SA, Mpindi JP, Kallioniemi O, Honkela A, Aittokallio T, Wennerberg K, NDC (including Li J), Collins JJ, Gallahan D, Singer D, Saez-Rodriguez J, Kaski S, Gray JW, Stolovitzky G. A community effort to assess and improve drug sensitivity prediction algorithms. Nature Biotechnology 32(12):1202-12, 2014. e-Pub 2014. PMID: 24880487.
- Hoadley, KA, Yau, C, Wolf, D, Cherniack, AD, Tamborero, D, Ng, S, Leiserson, MD, Niu, B, McLellan, MD, Uzunangelov, V, Zhang, J, Kandoth, C, Akbani, R, Shen, H, Omberg, L, Chu, A, Margolin, AA, Van't Veer, L, Lopez-Bigas, N, Laird, PW, Byers, LA, Mills, GB, Weinstein, JN, Aldape, KD, Baggerly, KA, Bristow, C, Broom, BM, Chin, L, Edgerton, ME, Hamilton, SR, Han, L, Ju, Z, Kim, H, Li, J, Liang, H, Liu, W, Liu, Y, Lorenzi, PL, Lu, Y, McGuire, SE, Song, X, Su, X, Verhaak, R, Wu, C, Wu, C, Yao, J, Yuan, Y, Zhang, W, Zhao, W, Zheng, S. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell 158(4):929-944, 2014. e-Pub 2014. PMID: 25109877.
- Han L, Yuan Y, Zheng S, Yang Y, Li J, Edgerton ME, Diao L, Xu Y, Verhaak RGW, Liang H. The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes. Nature Communications 5:3963, 2014. e-Pub 2014. PMID: 24999802.
- Akbani R, Ng PK, Werner HM, Shahmoradgoli M, Zhang F, Ju Z, Liu W, Yang JY, Yoshihara K, Li J, Ling S, Seviour EG, Ram PT, Minna JD, Diao L, Tong P, Heymach JV, Hill SM, Dondelinger F, Städler N, Byers LA, Meric-Bernstam F, Weinstein JN, Broom BM, Verhaak RG, Liang H, Mukherjee S, Lu Y, Mills GB. A pan-cancer proteomic perspective on The Cancer Genome Atlas. Nature Communications 5:3887, 2014. e-Pub 2014. PMID: 24871328.
- Yang Y, Han L, Yuan Y, Li J, Hei N, Liang H. Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types. Nature Communications 5:3231, 2014. e-Pub 2014. PMID: 24488081.
- Li J, Lu Y, Akbani R, Ju Z, Roebuck PL, Liu W, Yang JY, Broom BM, Verhaak RG, Kane DW, Wakefield C, Weinstein JN, Mills GB, Liang H. TCPA: a resource for cancer functional proteomics data. Nature Methods 10(11):1046-7, 2013. e-Pub 2013. PMID: 24037243.
- CGARN (including Li J), Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nature Genetics 45(10):1113-20, 2013. e-Pub 2013. PMID: 24071849.
- Yang J, Li J, Grünewald S, Wan XF. BinAligner: a heuristic method to align biological networks. BMC Bioinformatics 14 Suppl 14(SUPPL.14):S8, 2013. e-Pub 2013. PMID: 24266981.
- Li J, Roebuck P, Grünewald S, Liang H. SurvNet: a web server for identifying network-based biomarkers that most correlate with patient survival data. Nucleic Acids Research 40(Web Server issue):W123-6, 2012. e-Pub 2012. PMID: 22570412.
- Yang J, Li J, Dong L, Grünewald S. Analysis on the reconstruction accuracy of the Fitch method for inferring ancestral states. BMC Bioinformatics 12:18, 2011. e-Pub 2011. PMID: 21226965.
- Yang J, Li J, Dong L, Grunewald S. A Heuristic Algorithm to Align Protein Interaction Networks. Journal of Biomathematics, 2011. e-Pub 2011.
- Li J, Yang J, Li F, Hu K, Dong L, Grunewald S. Pairwise Alignment of Protein-Protein Interaction by Linear Programming. Acta Biophysica Sinica, 2010. e-Pub 2010.
- Liu W*, Li J*, Tang Y, Liu C, Song M, Ju Z, Kumar SV, Lu Y, Akbani R, Mills G, Liang H. TCPAplus: An LLM-empowered Chatbot for Analyzing a Large Protein Expression Atlas of Human Cancers. Nature Communications (minor revision).
Book Chapters
- Siwak DR, Li J, Akbani R, Liang H, Lu Y. Analytical Platforms 3: Processing Samples via the RPPA Pipeline to Generate Large-Scale Data for Clinical Studies. In: Adv Exp Med Biol. Springer, 113-147, 2019.
- Labrie M, Fang Y, Kendsersky ND, Li J, Liang H, Westin SN, Mitri Z, Mills GB. Using Reverse Phase Protein Array (RPPA) to Identify and Target Adaptive Resistance. In: Adv Exp Med Biol. Springer, 251-266, 2019.
Selected Presentations & Talks
Local Presentations
- 2024. An Expanded Quantitative Protein Expression Atlas of Human Cancers. Invited. BCB Seminar. Houston, Texas, US.
- 2023. RPPA results and beyond - The Cancer Proteome Atlas Portal (TCPA). Invited. RPPA Core 200K Milestone Celebration. Houston, Texas, US.
- 2015. TCPA: A resource for cancer functional proteomic data. Poster. iBRIGHT. Houston, Texas, US.
- 2015. TANRIC: An interactive open platform to explore the function of lncRNAs in cancer. Poster. iBRIGHT. Houston, Texas, US.
- 2015. TCPA: A Resource for Cancer Functional Proteomics Data. Conference. Society of Chinese Bioscientists in America - Texas Annual Symposium. Houston, TX, US.
- 2013. TCPA: A Resource for Cancer Functional Proteomics Data. Poster. Symposia on Cancer Research, US.
- 2012. SurvNet: a web server for identifying network-based biomarkers that most correlate with patient survival data. Conference. MD Anderson Trainee Research Day. Houston, Texas, US.
Regional Presentations
- 2016. A comprehensive proteogenomic characterization of human cancer cell lines. Conference. Society of Chinese Bioscientists in America - Texas Annual Symposium. Houston, TX, US.
- 2015. TANRIC: An Interactive Open Platform to Explore the Function of LncRNAs in Cancer. Poster. CPRIT’s 2015 Innovations in Cancer Prevention and Research Conference. Austin, TX, US.
- 2015. TANRIC: An interactive open platform to explore the function of lncRNAs in cancer. Poster. The Hallmarks of Cancer Symposium. Houston, TX, US.
National Presentations
- 2024. The Cancer Proteome Atlas: Expanded datasets and empowered with an AI-driven chatbot. Poster. AACR Annual Meeting, US.
- 2023. An Expanded Quantitative Protein Expression Atlas of Human Cancers. Poster. AACR Annual Meeting, US.
- 2022. DrBioRight: a next-generation analytics platform for analyzing omics data. Poster. ITCR Annual Meeting, US.
- 2022. TCPA: An open access resource for cancer functional proteomics data. Poster. ITCR Annual Meeting, US.
- 2021. TCPA: An Integrated Bioinformatics Resource for Functional Cancer Proteomic Data. Poster. ITCR Annual Meeting, US.
- 2021. A functional genomic approach to actionable gene fusions for precision oncology. Conference. OHSU site visit CTD2. Portland, OR, US.
- 2021. A natural language-oriented analytics platform for cancer omics data. Conference. GTC2021, US.
- 2020. An atlas of perturbed functional proteomics profiles of cancer cell lines. Poster. AACR 2020 Virtual Annual Meeing, US.
- 2020. DrOncoRight: A natural language-oriented analytics platform for cancer omics data. Conference. AACR 2020 Virtual Annual Meeting, US.
- 2020. TCPA: An Integrated Bioinformatics Resource for Functional Cancer Proteomic Data. Conference. ITCR Virtual Annual Meeting, US.
- 2020. An Atlas of Perturbed Functional Proteomics Profiles of Cancer Cell Lines. Invited. CTD2 Virtual Site Visit, US.
- 2019. TCPA Pan-cancer Analytic Module: Protein-centric Analysis of Multi-omics Data in Human Cancer. Conference. ITCR Annual Meeting. Park City, UT, US.
- 2019. Systematic Identification of Cancer Therapeutic Liabilities Through Adaptive Functional Proteomics. Poster. AACR 2019 Annual Meeting. Atlanta, GA, US.
- 2018. The Cancer Proteome Atlas. Conference. Big Data and Cancer Precision Medicine. Boston, MA, US.
- 2018. The Cancer Proteome Atlas. Poster. ITCR 2018 Annual Meeting. Bethesda, MD, US.
- 2018. Functional annotation of somatic mutations in cancers. Conference. CTD2 Teleconference. Portland, OR, US.
- 2017. The Cancer Proteome Atlas. Poster. ITCR 2017 Annual Meeting. Santa Cruz, CA, US.
- 2017. TCPA: A Resource for Cancer Functional Proteomics Data. Conference. Pacific Symposium on Biocomputing 2017. The big island, Hawaii, US.
- 2015. A systematic network-based approach to prioritizing lncRNA drivers in cancers. Poster. AACR Noncoding RNAs and Cancer conference. Boston, MA, US.
- 2014. TCPA: A Resource for Cancer Functional Proteomics Data. Poster. The Cancer Genome Atlas’ 3rd Annual Scientific Symposium. Bethesda, MD, US.
Formal Peers
- 2020. An Atlas of Perturbed Functional Proteomics Profiles of Cancer Cell Lines. Invited. An Atlas of Perturbed Functional Proteomics Profiles of Cancer Cell Lines. Portland, OR, US.
Grant & Contract Support
Date: | 2025 - 2027 |
Title: | Proteomics-driven precision molecular mapping of patient tumors to preclinical models in lung cancer |
Funding Source: | NIH/NCI |
Role: | PI |
ID: | 1R21CA288901-01A1 |
Date: | 2023 - 2025 |
Title: | Systematic identification of synthetic lethal interactions through functional proteomics |
Funding Source: | UT MD Anderson Cancer Center |
Role: | PI |
ID: | 2023-00062105-Y1 |
Date: | 2022 - 2027 |
Title: | The Cancer Proteome Atlas: an Integrated Bioinformatics Resource for Functional Cancer Proteomic Data |
Funding Source: | NCI |
Role: | Co-I |
ID: | 1 U24 CA 264128 - 01A1 |
Date: | 2020 - 2027 |
Title: | Barnhart Family Distinguished Professorship in Targeted Therapies |
Funding Source: | Barnhart Family Distinguished Professorship |
Role: | Collaborator |
ID: | 600815-80-101635-50 |
Date: | 2020 - 2025 |
Title: | Characterization and modeling of m6A RNA methylation in cancer |
Funding Source: | NIH/NCI |
Role: | Co-I |
ID: | 5 R01 CA 251150 - 03 |
Date: | 2019 - 2024 |
Title: | Cancer Center Support (CORE) Grant: RPPA Core GY45 CCSG |
Funding Source: | The University of Texas MD Anderson Cancer Center |
Role: | Collaborator |
ID: | 5 P30 CA 016672 -04 |
Patient Reviews
CV information above last modified April 15, 2025