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      Ke Li Image

      Ke Li, PhD

      Department of Imaging Physics, Division of Diagnostic Imaging

      Present Title & Affiliation

      Primary Appointment

      Associate Professor, Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX

      Dual/Joint/Adjunct Appointment

      Associate Professor, Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX

      Associate Professor, Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas

      Research Interests

      CT and cone-beam CT imaging for cancer diagnosis and image-guided therapy. Exploration of novel AI or hardware technology for use in clinical CT imaging and interventional radiology

      Education & Training

      Degree-Granting Education

      2013University of Wisconsin, Madison, Wisconsin, US, Medical Physics, Ph.D
      2009Ohio State University, Columbus, Ohio, US, Physics, M.S
      2006Nanjing University, Nanjing, CN, Physics, BS

      Licenses & Certifications

      2024Texas Medical Physicist License
      2019American Board of Radiology - Board Certification in Diagnostic Medical Physics

      Experience & Service

      Faculty Academic Appointments

      Associate Professor with tenure, Medical Physics and Radiology, University of Wisconsin - Madison, Madison, WI, 2022 - 2024

      Tenure-track Assistant Professor, Medical Physics and Radiology, University of Wisconsin - Madison, Madison, WI, 2017 - 2022

      Clinical health science-track Assistant Professor, Medical Physics and Radiology, University of Wisconsin - Madison, Madison, WI, 2014 - 2016

      Assistant Scientist, Medical Physics, University of Wisconsin - Madison, Madison, WI, 2013 - 2014

      Honors & Awards

      2024AAPM John R. Cameron Early-Career Investigator Symposium Finalist (student: Linying Zhan), American Association of Physicists in Medicine (AAPM)
      2024AAPM Moses & Sylvia Greenfield Award, American Association of Physicists in Medicine (AAPM)
      2024UW-Madison Vilas Associates Competition Award, University of Wisconsin - Madison
      2023Distinguished Investigators of the Academy for Radiology and Biomedical Imaging Research, Academy for Radiology and Biomedical Imaging Research
      2023RSNA Trainee Research Prize Award,, Radiological Society of North America
      2023John R. Cameron Early-Career Investigator Symposium Finalist, American Association of Physicists in Medicine (AAPM)
      2023Runner-up, Robert F. Wagner All-Conference Best Student Paper Award,, SPIE Medical Imaging Conference
      2022RSNA Trainee Research Prize Award, RSNA Annual Meeting 2022
      2022Best In Physics Award, AAPM Annual Meeting 2022
      2022First Place, Robert F. Wagner All-Conference Best Student Paper Award, SPIE Medical Imaging Conference
      2022Medical Physics Journal Distinguished Associate Editor
      2021 - 2022Medical Physics Journal Distinguished Reviewer
      20212020 SPIE Community Champion
      2021Robert F. Wagner All-Conference Best Student Paper Award, SPIE Medical Imaging Conference
      2021American Association of Physicists in Medicine Moses & Sylvia Greenfield Award for the Best Imaging Paper published in Medical Physics during 2020, American Association of Physicists in Medicine (AAPM)
      2021Medical Physics journal front cover featured article and Editor’s Choice

      Professional Memberships

      International Society for Computed Tomography

      2023 - Present

      Society of Photo-Optical Instrumentation Engineers

      2018 - Present

      American Association of Physicists in Medicine

      2014 - Present

      Grant & Contract Support

      Date: 2025 - 2029
      Title:IG-RABIT: Image-Guided, Robot-Assisted, Biomechanically-Informed Osteotomy and Surgical Implants for Orthopaedic Oncology
      Funding Source:UT MDACC Accelerator Program
      Role:Key Personnel
      Date: 2024 - 2026
      Title:On-board Photon Counting Detector Cone Beam CT-guided Proton Therapy
      Funding Source:University of Wisconsin-Madison Vilas Associate Competition Award
      Role:PI
      Date: 2023 - 2027
      Title:Next Generation Cone Beam CT with Improved Contrast Resolution and Added Spectral Imaging Functionality
      Funding Source:NIH
      Role:Co-I
      ID:R01EB034011-01A1
      Date: 2022 - 2026
      Title:Clinical Translation of a One-Stop-Shop Imaging Method for Abdominal CT Applications
      Funding Source:NIH
      Role:Co-I
      ID:R01EB032374-01A1
      Date: 2021 - 2025
      Title:Functional Lung Imaging Using a Single kV CT Acquisition
      Funding Source:NIH
      Role:Co-PI
      ID:1R01HL153594-04

      Selected Publications

      Peer-Reviewed Articles

      1. Li, K, Liu, X, Jacobsen, MC, Rong, J, Jensen, CT, Tamm, EP, Dong, F. User evaluation of detector performance in clinical photon-counting and energy-integrating CT scanners using DICOM images. Medical physics 52(10), 2025. e-Pub 2025. PMID: 41046473.
      2. Monsivais, H, Liu, X, Dong, F, Jacobsen, MC, Rong, J, Jensen, CT, Li, K. Three-dimensional noise characteristics of clinical photon counting detector CT. Medical physics 52(10), 2025. e-Pub 2025. PMID: 41058450.
      3. Zhan, L, Chen, GH, Li, K. Quantifying photon counting detector (PCD) performance using PCD-CT images. Medical physics 52(5):2796-2809, 2025. e-Pub 2025. PMID: 39971720.
      4. Garrett, J, Capel, K, Eisenmenger, L, Ahmed, A, Niemann, D, Li, Y, Li, K, Griner, D, Schafer, S, Strother, C, Chen, GH, Aagaard-Kienitz, B. Comparison of sequential multi-detector CT and cone-beam CT perfusion maps in 39 subjects with anterior circulation acute ischemic stroke due to a large vessel occlusion. Journal of Medical Imaging 11(6), 2024. e-Pub 2024. PMID: 39634326.
      5. Hallett JE, Bruza P, Jermyn M, Li K, Pogue BW. Noise & mottle suppression methods for cumulative Cherenkov images of radiation therapy delivery. Phys Med Biol 69(22), 2024. e-Pub 2024. PMID: 39474803.
      6. Leng S, Toia GV, Hoodeshenas S, Ramirez-Giraldo JC, Yagil Y, Maltz JS, Boedeker K, Li K, Baffour F, Fletcher JG. Standardizing technical parameters and terms for abdominopelvic photon-counting CT: laying the groundwork for innovation and evidence sharing. Abdom Radiol (NY) 49(9):3261-3273, 2024. e-Pub 2024. PMID: 38769199.
      7. Zhang C, Li K, Zhang R, Chen GH. Noise power spectrum (NPS) in computed tomography: Enabling local NPS measurement without stationarity and ergodicity assumptions. Med Phys 51(7):4655-4672, 2024. e-Pub 2024. PMID: 38709982.
      8. Lawless M, Byrns K, Bednarz BP, Meudt J, Shanmuganayagam D, Shah J, McMillan A, Li K, Pirasteh A, Miller J. Feasibility of identifying proliferative active bone marrow with fat fraction MRI and multi-energy CT. Phys Med Biol 69(13), 2024. e-Pub 2024. PMID: 38876111.
      9. Zhang C, Li K, Zhang R, Chen GH. Experimental measurement of local noise power spectrum (NPS) in photon counting detector-CT (PCD-CT) using a single data acquisition. Med Phys 51(6):4081-4094, 2024. e-Pub 2024. PMID: 38703355.
      10. Li KY, Pickett KA, Fu HW, Chen RS. Proprioceptive and olfactory deficits in individuals with Parkinson disease and mild cognitive impairment. Acta Neurol Belg 124(2):419-430, 2024. e-Pub 2024. PMID: 37962784.
      11. Griner D, Lei N, Chen GH, Li K. Correcting statistical CT number biases without access to raw detector counts: Applications to high spatial resolution photon counting CT imaging. Med Phys 50(10):6022-6035, 2023. e-Pub 2023. PMID: 37517080.
      12. Treb K, Radtke J, Culberson WS, Li K. Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors. Phys Med Biol 68(15), 2023. e-Pub 2023. PMID: 37379858.
      13. Treb K, Hamisch Y, Ullberg C, Zhang R, Li K. Photon counting-energy integrating hybrid flat panel detector systems for image-guided interventions: an experimental proof-of-concept. Phys Med Biol 68(13), 2023. e-Pub 2023. PMID: 37307849.
      14. Li, K, Chen, JR, Feng, M. Construction of a Nearly Unbiased Statistical Estimator of Sinogram to Address CT Number Bias Issues in Low-Dose Photon Counting CT. IEEE Transactions on Medical Imaging 42(6):1846-1858, 2023. e-Pub 2023. PMID: 37022268.
      15. Li Y, Tie X, Li K, Zhang R, Qi Z, Budde A, Grist TM, Chen GH. A quality-checked and physics-constrained deep learning method to estimate material basis images from single-kV contrast-enhanced chest CT scans. Med Phys 50(6):3368-3388, 2023. e-Pub 2023. PMID: 36908250.
      16. Bushe D, Zhang R, Chen GH, Li K. Unbiased zero-count correction method in low-dose high-resolution photon counting detector CT. Phys Med Biol 68(11), 2023. e-Pub 2023. PMID: 37137314.
      17. Cai EY, De Caro C, Treb K, Li K. Benefits of using removable filters in dual-layer flat panel detectors. Phys Med Biol 68(8), 2023. e-Pub 2023. PMID: 36963117.
      18. Flakus MJ, Wuschner AE, Wallat EM, Shao W, Shanmuganayagam D, Christensen GE, Reinhardt JM, Li K, Bayouth JE. Quantifying robustness of CT-ventilation biomarkers to image noise. Front Physiol 14:1040028, 2023. e-Pub 2023. PMID: 36866176.
      19. Treb K, Ji X, Feng M, Zhang R, Periyasamy S, Laeseke PF, Dingle AM, Brace CL, Li K. A C-arm photon counting CT prototype with volumetric coverage using multi-sweep step-and-shoot acquisitions. Phys Med Biol 67(21), 2022. e-Pub 2022. PMID: 36162399.
      20. Lubner MG, Ziemlewicz TJ, Wells SA, Li K, Wu PH, Hinshaw JL, Lee FT Jr, Brace CL. Advanced CT techniques for hepatic microwave ablation zone monitoring and follow-up. Abdom Radiol (NY) 47(8):2658-2668, 2022. e-Pub 2022. PMID: 34731282.
      21. Montoya JC, Zhang C, Li Y, Li K, Chen GH. Reconstruction of three-dimensional tomographic patient models for radiation dose modulation in CT from two scout views using deep learning. Med Phys 49(2):901-916, 2022. e-Pub 2022. PMID: 34908175.
      22. Ji X, Feng M, Treb K, Zhang R, Schafer S, Li K. Development of an Integrated C-Arm Interventional Imaging System With a Strip Photon Counting Detector and a Flat Panel Detector. IEEE Trans Med Imaging 40(12):3674-3685, 2021. e-Pub 2021. PMID: 34232872.
      23. Lan X, Fan K, Li K, Cai W. Dynamic PET imaging with ultra-low-activity of 18F-FDG: unleashing the potential of total-body PET. Eur J Nucl Med Mol Imaging 48(13):4138-4141, 2021. e-Pub 2021. PMID: 33515054.
      24. Li K, Li Y, Qi Z, Garrett JW, Grist TM, Chen GH. Quantitative lung perfusion blood volume using dual energy CT-based effective atomic number (Zeff ) imaging. Med Phys 48(11):6658-6672, 2021. e-Pub 2021. PMID: 34520066.
      25. Lan X, Younis MH, Li K, Cai W. First clinical experience of 106 cm, long axial field-of-view (LAFOV) PET/CT: an elegant balance between standard axial (23 cm) and total-body (194 cm) systems. Eur J Nucl Med Mol Imaging 48(12):3755-3759, 2021. e-Pub 2021. PMID: 34424375.
      26. Hayes JW, Montoya J, Budde A, Zhang C, Li Y, Li K, Hsieh J, Chen GH. High Pitch Helical CT Reconstruction. IEEE Trans Med Imaging 40(11):3077-3088, 2021. e-Pub 2021. PMID: 34029189.
      27. Feng M, Ji X, Zhang R, Treb K, Dingle AM, Li K. An experimental method to correct low-frequency concentric artifacts in photon counting CT. Phys Med Biol 66(17), 2021. e-Pub 2021. PMID: 34315142.
      28. Zhao R, Hernando D, Harris DT, Hinshaw LA, Li K, Ananthakrishnan L, Bashir MR, Duan X, Ghasabeh MA, Kamel IR, Lowry C, Mahesh M, Marin D, Miller J, Pickhardt PJ, Shaffer J, Yokoo T, Brittain JH, Reeder SB. Multisite multivendor validation of a quantitative MRI and CT compatible fat phantom. Med Phys 48(8):4375-4386, 2021. e-Pub 2021. PMID: 34105167.
      29. Ji X, Treb K, Li K. Anomalous edge response of cadmium telluride-based photon counting detectors jointly caused by high-flux radiation and inter-pixel communication. Phys Med Biol 66(8), 2021. e-Pub 2021. PMID: 33765661.
      30. Zhang R, Tie X, Qi Z, Bevins NB, Zhang C, Griner D, Song TK, Nadig JD, Schiebler ML, Garrett JW, Li K, Reeder SB, Chen GH. Diagnosis of Coronavirus Disease 2019 Pneumonia by Using Chest Radiography: Value of Artificial Intelligence. Radiology 298(2):E88-E97, 2021. e-Pub 2021. PMID: 32969761.
      31. Treb K, Feng M, Ji X, Zhang R, Schafer S, Li K. A hybrid photon counting and flat panel detector system for periprocedural hemorrhage monitoring in the angio suite. Proceedings of SPIE 11595(115950U), 2021. e-Pub 2021.
      32. Li K, Zhang R, Cai W. Deep learning convolutional neural network (DLCNN): unleashing the potential of 18F-FDG PET/CT in lymphoma. Am J Nucl Med Mol Imaging 11(4):327-331, 2021. e-Pub 2021. PMID: 34513286.
      33. Zhang C, Li Y, Li K, Chen GH. DeepInterior: new pathway to address the interior tomographic reconstruction problem in CT via direct backprojecting divergent beam projection data. Proceedings of SPIE 11595(115951Q), 2021. e-Pub 2021.
      34. Treb K, Li K. Accuracy of weighted CTDI in estimating average dose delivered to CTDI phantoms: An experimental study. Med Phys 47(12):6484-6499, 2020. e-Pub 2020. PMID: 33034041.
      35. Harvey EC, Li K. Leveraging non-contrast head CT to improve the image quality of cerebral CT perfusion maps. J Med Imaging (Bellingham) 7(6):063504, 2020. e-Pub 2020. PMID: 33363247.
      36. Ji X, Zhang R, Li K, Chen GH. Dual Energy Differential Phase Contrast CT (DE-DPC-CT) Imaging. IEEE Trans Med Imaging 39(11):3278-3289, 2020. e-Pub 2020. PMID: 32340940.
      37. Zhang R, Fowler AM, Wilke LG, Kelcz F, Garrett JW, Chen GH, Li K. Fast acquisition with seamless stage translation (FASST) for a trimodal x-ray breast imaging system. Med Phys 47(9):4356-4362, 2020. e-Pub 2020. PMID: 32458449.
      38. Cao L, Zhu C, Eisenmenger L, Du X, Liu J, Yang Q, Lu J, Li K, Saloner D. Wall enhancement characteristics of vertebrobasilar nonsaccular aneurysms and their relationship to symptoms. Eur J Radiol 129:109064, 2020. e-Pub 2020. PMID: 32474380.
      39. Li Y, Garrett JW, Li K, Strother C, Chen GH. An Enhanced SMART-RECON Algorithm for Time-Resolved C-Arm Cone-Beam CT Imaging. IEEE Trans Med Imaging 39(6):1894-1905, 2020. e-Pub 2020. PMID: 31870980.
      40. Ji X, Zhang R, Li K, Chen GH. Is high sensitivity always desirable for a grating-based differential phase contrast imaging system?. Med Phys 47(3):1215-1228, 2020. e-Pub 2020. PMID: 31872886.
      41. Griner D, Garrett JW, Li Y, Li K, Chen GH. Correction for cone beam CT image artifacts via a deep learning method. Proceedings of SPIE 11312(113124H), 2020. e-Pub 2020.
      42. Feng M, Ji X, Zhang R, Miller J, Chen GH, Li K. Impact of photon counting detector spectral distortion on virtual non-contrast CT imaging. Proceedings of SPIE 11312(1131255), 2020. e-Pub 2020.
      43. Harvey E, Li K. Non-contrast head CT-assisted cerebral CT perfusion imaging. Proceedings of SPIE 11312(1131114), 2020. e-Pub 2020.
      44. Li Y, Cruz-Batisda JP, Li K, Bushe D, Francois C, Lubner MG, Chen GH. Feasibility of achieving spectral CT imaging from a single KV acquisition and deep learning method. Proceedings of SPIE 11312(1131222), 2020. e-Pub 2020.
      45. Li K, Strother CM, Chen GH. Statistical properties of cerebral CT perfusion imaging systems. Part I. Cerebral blood volume maps generated from nondeconvolution-based systems. Med Phys 46(11):4869-4880, 2019. e-Pub 2019. PMID: 31487396.
      46. Li K, Chen GH. Statistical properties of cerebral CT perfusion imaging systems. Part II. Deconvolution-based systems. Med Phys 46(11):4881-4897, 2019. e-Pub 2019. PMID: 31495935.
      47. Ji X, Zhang R, Chen GH, Li K. Task-driven optimization of the non-spectral mode of photon counting CT for intracranial hemorrhage assessment. Phys Med Biol 64(21):215014, 2019. e-Pub 2019. PMID: 31509812.
      48. Li Y, Li K, Zhang C, Montoya J, Chen GH. Learning to Reconstruct Computed Tomography Images Directly From Sinogram Data Under A Variety of Data Acquisition Conditions. IEEE Trans Med Imaging 38(10):2469-2481, 2019. e-Pub 2019. PMID: 30990179.
      49. Harvey EC, Feng M, Ji X, Zhang R, Li Y, Chen GH, Li K. Impacts of photon counting CT to maximum intensity projection (MIP) images of cerebral CT angiography: theoretical and experimental studies. Phys Med Biol 64(18):185015, 2019. e-Pub 2019. PMID: 31315093.
      50. Cruz-Bastida JP, Zhang R, Gomez-Cardona D, Hayes J, Li K, Chen GH. Impact of noise reduction schemes on quantitative accuracy of CT numbers. Med Phys 46(7):3013-3024, 2019. e-Pub 2019. PMID: 31004439.
      51. Ji X, Feng M, Zhang R, Chen GH, Li K. An experimental method to directly measure DQE(k) at k=0 for 2D x-ray imaging systems. Phys Med Biol 64(7):075013-75013, 2019. e-Pub 2019. PMID: 30884472.
      52. Planz VB, Posielski NM, Lubner MG, Li K, Chen GH, Nakada SY, Pickhardt PJ. Ultra-low-dose limited renal CT for volumetric stone surveillance: advantages over standard unenhanced CT. Abdom Radiol (NY) 44(1):227-233, 2019. e-Pub 2019. PMID: 30073402.
      53. Garrett JW, Li Y, Li K, Wu Y, Johnson K, Schafer S, Chen GH. Quantification of temporal resolution improvement factor in SMART-RECON based time-resolved C-arm Cone beam computed tomography angiography (TR-CBCTA). Phys Med Biol 63(19):19NT02, 2018. e-Pub 2018. PMID: 30196276.
      54. Zhang R, Cruz-Bastida JP, Gomez-Cardona D, Hayes JW, Li K, Chen GH. Quantitative accuracy of CT numbers: Theoretical analyses and experimental studies. Med Phys 45(10):4519-4528, 2018. e-Pub 2018. PMID: 30102414.
      55. Pickhardt PJ, Graffy PM, Reeder SB, Hernando D, Li K. Quantification of Liver Fat Content With Unenhanced MDCT: Phantom and Clinical Correlation With MRI Proton Density Fat Fraction. AJR Am J Roentgenol 211(3):W151-W157, 2018. e-Pub 2018. PMID: 30016142.
      56. Ji X, Zhang R, Chen GH, Li K. Impact of anti-charge sharing on the zero-frequency detective quantum efficiency of CdTe-based photon counting detector system: cascaded systems analysis and experimental validation. Phys Med Biol 63(9):095003, 2018. e-Pub 2018. PMID: 29582785.
      57. Hayes JW, Gomez-Cardona D, Zhang R, Li K, Cruz-Bastida JP, Chen GH. Low-dose cone-beam CT via raw counts domain low-signal correction schemes: Performance assessment and task-based parameter optimization (Part I: Assessment of spatial resolution and noise performance). Med Phys 45(5):1942-1956, 2018. e-Pub 2018. PMID: 29532483.
      58. Garrett JW, Li Y, Li K, Chen GH. Reduced anatomical clutter in digital breast tomosynthesis with statistical iterative reconstruction. Med Phys 45(5):2009-2022, 2018. e-Pub 2018. PMID: 29542821.
      59. Li Y, Garrett JW, Li K, Wu Y, Johnson K, Schafer S, Strother C, Chen GH. Time-resolved C-arm cone beam CT angiography (TR-CBCTA) imaging from a single short-scan C-arm cone beam CT acquisition with intra-arterial contrast injection. Phys Med Biol 63(7):075001, 2018. e-Pub 2018. PMID: 29494345.
      60. Ge Y, Ji X, Zhang R, Li K, Chen GH. K-edge energy-based calibration method for photon counting detectors. Phys Med Biol 63(1):015022, 2017. e-Pub 2017. PMID: 29072192.
      61. Cruz-Bastida JP, Gomez-Cardona D, Garrett J, Szczykutowicz T, Chen GH, Li K. Modified ideal observer model (MIOM) for high-contrast and high-spatial resolution CT imaging tasks. Med Phys 44(9):4496-4505, 2017. e-Pub 2017. PMID: 28600849.
      62. Ji X, Ge Y, Zhang R, Li K, Chen GH. Studies of signal estimation bias in grating-based x-ray multicontrast imaging. Med Phys 44(6):2453-2465, 2017. e-Pub 2017. PMID: 28339107.
      63. Pooler BD, Lubner MG, Kim DH, Chen OT, Li K, Chen GH, Pickhardt PJ. Prospective Evaluation of Reduced Dose Computed Tomography for the Detection of Low-Contrast Liver Lesions: Direct Comparison with Concurrent Standard Dose Imaging. Eur Radiol 27(5):2055-2066, 2017. e-Pub 2017. PMID: 27595834.
      64. Chen Y, Budde A, Li K, Li Y, Hsieh J, Chen GH. A platform-independent method to reduce CT truncation artifacts using discriminative dictionary representations. Med Phys 44(1):121-131, 2017. e-Pub 2017. PMID: 28102942.
      65. Gomez-Cardona D, Cruz-Bastida JP, Li K, Budde A, Hsieh J, Chen GH. Impact of bowtie filter and object position on the two-dimensional noise power spectrum of a clinical MDCT system. Med Phys 43(8):4495, 2016. e-Pub 2016. PMID: 27487866.
      66. Bannas P, Li Y, Motosugi U, Li K, Lubner M, Chen GH, Pickhardt PJ. Prior Image Constrained Compressed Sensing Metal Artifact Reduction (PICCS-MAR): 2D and 3D Image Quality Improvement with Hip Prostheses at CT Colonography. Eur Radiol 26(7):2039-46, 2016. e-Pub 2016. PMID: 26521266.
      67. Cruz-Bastida JP, Gomez-Cardona D, Li K, Sun H, Hsieh J, Szczykutowicz TP, Chen GH. Hi-Res scan mode in clinical MDCT systems: Experimental assessment of spatial resolution performance. Med Phys 43(5):2399, 2016. e-Pub 2016. PMID: 27147351.
      68. Gomez-Cardona D, Li K, Hsieh J, Lubner MG, Pickhardt PJ, Chen GH. Can conclusions drawn from phantom-based image noise assessments be generalized to in vivo studies for the nonlinear model-based iterative reconstruction method?. Med Phys 43(2):687-95, 2016. e-Pub 2016. PMID: 26843232.
      69. Gomez-Cardona D, Nagle SK, Li K, Robinson TE, Chen GH. Influence of radiation dose and reconstruction algorithm in MDCT assessment of airway wall thickness: A phantom study. Med Phys 42(10):5919-27, 2015. e-Pub 2015. PMID: 26429266.
      70. Li K, Gomez-Cardona D, Hsieh J, Lubner MG, Pickhardt PJ, Chen GH. Statistical model based iterative reconstruction in clinical CT systems. Part III. Task-based kV/mAs optimization for radiation dose reduction. Med Phys 42(9):5209-21, 2015. e-Pub 2015. PMID: 26328971.
      71. Lubner MG, Pooler BD, Kitchin DR, Tang J, Li K, Kim DH, Munoz del Rio A, Chen GH, Pickhardt PJ. Sub-milliSievert (sub-mSv) CT colonography: a prospective comparison of image quality and polyp conspicuity at reduced-dose versus standard-dose imaging. Eur Radiol 25(7):2089-102, 2015. e-Pub 2015. PMID: 25903700.
      72. Li K, Garrett J, Ge Y, Chen GH. Statistical model based iterative reconstruction (MBIR) in clinical CT systems. Part II. Experimental assessment of spatial resolution performance. Med Phys 41(7):071911, 2014. e-Pub 2014. PMID: 24989389.
      73. Li K, Ge Y, Garrett J, Bevins N, Zambelli J, Chen GH. Grating-based phase contrast tomosynthesis imaging: proof-of-concept experimental studies. Med Phys 41(1):011903, 2014. e-Pub 2014. PMID: 24387511.
      74. Li K, Garrett J, Chen GH. Correlation between human observer performance and model observer performance in differential phase contrast CT. Med Phys 40(11):111905, 2013. e-Pub 2013. PMID: 24320438.
      75. Li K, Zambelli J, Bevins N, Ge Y, Chen GH. Spatial resolution characterization of differential phase contrast CT systems via modulation transfer function (MTF) measurements. Phys Med Biol 58(12):4119-35, 2013. e-Pub 2013. PMID: 23685949.
      76. Li K, Bevins N, Zambelli J, Chen GH. Fundamental relationship between the noise properties of grating-based differential phase contrast CT and absorption CT: theoretical framework using a cascaded system model and experimental validation. Med Phys 40(2):021908, 2013. e-Pub 2013. PMID: 23387756.
      77. Bevins N, Zambelli J, Li K, Qi Z, Chen GH. Multicontrast x-ray computed tomography imaging using Talbot-Lau interferometry without phase stepping. Med Phys 39(1):424-8, 2012. e-Pub 2012. PMID: 22225312.
      78. Chen GH, Zambelli J, Li K, Bevins N, Qi Z. Scaling law for noise variance and spatial resolution in differential phase contrast computed tomography. Med Phys 38(2):584-8, 2011. e-Pub 2011. PMID: 21452695.
      79. Chen GH, Zambelli J, Bevins N, Qi Z, Li K. X-ray phase sensitive imaging methods: basic physical principles and potential medical applications. Curr Med Imaging Rev 6(2):90-99, 2010. e-Pub 2010. PMID: 23970846.

      Book Chapters

      1. Li K, Chen GH. CT Image Quality Characterization. In: Computed Tomography: New Approaches, Applications, and Operators. Springer, 85-124, 2020.
      2. Li K, Chen GH. Chapter 52: X-ray Phase Contrast Tomosynthesis Imaging. In: Handbook of X-Ray Imaging, 2018.
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