Ke Pan
Department of Melanoma Medical Oncology, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Melanoma Med Onco - Rsch, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
Dual/Joint/Adjunct Appointment
Assistant Professor, Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2006 | South China Agricultural University, Guangzhou, CN, Immunology, PhD |
| 2000 | South China Agricultural University, Guangzhou, CN, Biochemistry, Bachelor |
Postgraduate Training
| 2006-2009 | Postdoc, Immunology and Oncology, Sun Yat-sen University Cancer Center, Guangzhou |
Experience & Service
Faculty Academic Appointments
Visiting Scientist, Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2014 - 2016
Associate Professor, Department of Experiment Research, Sun Yat-sen University Cancer Center, Guangzhou, 2014 - 2014
Assistant Professor, Department of Experiment Research, Sun Yat-sen University Cancer Center, Guangzhou, 2009 - 2013
Other Professional Positions
Senior Research Scientist, T cell immunotherapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2017 - 2023
Research Scientist, T cell immunotherapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2016 - 2017
Selected Presentations & Talks
National Presentations
- 2019. Identification of HLA-A0201 restricted epitope of cancer/testis antigen (CTA) Hormad1 and generation of antigen-specific T-cell receptor-engineered T cells (TCR-T) for treatment of solid tumor malignancies. Poster. 2019 AACR Special Conference on Tumor Immunology and Immunotherapy. Boston, Massachusetts, US.
- 2018. Generation of antigen-specific T cells and T-cell receptor engineered T cells (TCR-T) to cancer testis antigen MAGE-B2. Invited. 4th Annual Immuno-Oncology Young Investigators’ Forum, 2018. Houston, TX, US.
- 2018. Identification of HLA-A0201 restricted epitope of novel cancer/testis antigens VCX/Y and generation of antigen-specific T-cell receptor engineered T cells for treatment of solid tumor malignancies. Poster. 2018 ASCO-SITC Clinical Immuno-Oncology Symposium. San Francisco, CA, US.
Grant & Contract Support
| Date: | 2026 - 2028 |
| Title: | Engineered T cells targeting TPX2 as the novel immunotherapeutic approach for glioblastoma |
| Funding Source: | AMERICAN CANCER SOCIETY |
| Role: | PI |
| ID: | FP28573 |
| Date: | 2024 - Present |
| Title: | Identification of T cell receptor (TCR) targets for adoptive cell therapy of cholangiocarcinoma |
| Funding Source: | ELSA U PARDEE FOUNDATION |
| Role: | PI |
| Date: | 2023 - 2025 |
| Title: | HORMAD-specific TGF-beta resistant memory T cells for treatment of patients with Gastro-esophageal Cancer |
| Funding Source: | NATIONAL CANCER INSTITUTE |
| Role: | Key |
| ID: | 5UG3CA283615 |
| Title: | An Exploration of the Tumor Immunopeptidome for Anaplastic Thyroid Cancer |
| Funding Source: | NATIONAL INSTITUTES OF HEALTH |
| Role: | Key |
Selected Publications
Peer-Reviewed Articles
- Zheng, MM, Xia, Y, Pan, K, Sun, F, Tan, AC, Dong, X, Tu, H, Tang, LB, Li, YS, Yin, K, Borgeaud, M, Singhal, S, Zhu, E, Zhang, J, Nilsson, M, Wu, J, Gibbons, DL, Wakelee, HA, Neal, JW, Lee, JJ, Vaporciyan, AA, Ringsurongkawong, W, Tran, HT, Zhang, RZ, Zhang, T, Zhou, Q, Zhong, WZ, Li, W, Zhang, Y, Riess, JW, Addeo, A, Heymach, JV, Myall, NJ, Tan, DS, Wu, YL, Le, X. The evolving landscape of leptomeningeal metastases from NSCLC. Annals of Oncology 37(1):104-116, 2026. e-Pub 2026. PMID: 41125209.
- Pan, K, Chiu, Y, Huang, E, Chen, M, Wang, J, Lai, I, Singh, S, Shaw, RM, MacCoss, MJ, Yee, C. Mass spectrometric identification of immunogenic SARS-CoV-2 epitopes and cognate TCRs. Proceedings of the National Academy of Sciences of the United States of America 118(46), 2021. e-Pub 2021. PMID: 34725257.
- Hou, J, Wang, Y, Shi, L, Chen, Y, Xu, C, Saeedi, A, Pan, K, Bohat, R, Egan, NA, McKenzie, JA, Mbofung, RM, Williams, LJ, Yang, Z, Sun, M, Liang, X, Rodon Ahnert, J, Varadarajan, N, Yee, C, Chen, Y, Hwu, P, Peng, W. Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators. Journal for immunotherapy of cancer 9(2), 2021. e-Pub 2021. PMID: 33589527.
- Wang J, Hasan F, Frey AC, Li HS, Park J, Pan K, Haymaker C, Bernatchez C, Lee DA, Watowich SS, Yee C. Histone Deacetylase Inhibitors and IL21 Cooperate to Reprogram Human Effector CD8(+) T Cells to Memory T Cells. Cancer Immunol Res 8(6):794-805, 2020. e-Pub 2020. PMID: 32213626.
- Wang DD, Chen YB, Zhao JJ, Zhang XF, Zhu GC, Weng DS, Pan K, Lv L, Pan QZ, Jiang SS, Wang LL, Xia JC. TES functions as a Mena-dependent tumor suppressor in gastric cancer carcinogenesis and metastasis. Cancer Commun (Lond) 39(1):3, 2019. e-Pub 2019. PMID: 30728082.
- He LJ, Xie C, Li Y, Luo LN, Pan K, Gao XY, Liu LZ, Gao JM, Luo GY, Shan HB, Chen MY, Zhao C, Fan WJ, Yang P, Xu GL, Li JJ. Ultrasound-guided fine needle aspiration of retropharyngeal lymph nodes after radiotherapy for nasopharyngeal carcinoma: a novel technique for accurate diagnosis. Cancer Commun (Lond) 38(1):20, 2018. e-Pub 2018. PMID: 29764509.
- Zhang XF, Weng DS, Pan K, Zhou ZQ, Pan QZ, Zhao JJ, Tang Y, Jiang SS, Chen CL, Li YQ, Zhang HX, Chang AE, Wicha MS, Zeng YX, Li Q, Xia JC. Dendritic-cell-based immunotherapy evokes potent anti-tumor immune responses in CD105+ human renal cancer stem cells. Mol Carcinog 56(11):2499-2511, 2017. e-Pub 2017. PMID: 28621442.
- Park J, Talukder AH, Lim SA, Kim K, Pan K, Melendez B, Bradley SD, Jackson KR, Khalili JS, Wang J, Creasy C, Pan BF, Woodman SE, Bernatchez C, Hawke D, Hwu P, Lee KM, Roszik J, Lizee G, Yee C. SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity. Cancer Immunol Res 5(8):618-629, 2017. e-Pub 2017. PMID: 28630054.
- Chen CL, Pan QZ, Zhao JJ, Wang Y, Li YQ, Wang QJ, Pan K, Weng DS, Jiang SS, Tang Y, Zhang XF, Zhang HX, Zhou ZQ, Zeng YX, Xia JC. PD-L1 expression as a predictive biomarker for cytokine-induced killer cell immunotherapy in patients with hepatocellular carcinoma. Oncoimmunology 5(7):e1176653, 2016. e-Pub 2016. PMID: 27622026.
- Zhang XF, Pan K, Weng DS, Chen CL, Wang QJ, Zhao JJ, Pan QZ, Liu Q, Jiang SS, Li YQ, Zhang HX, Xia JC. Cytotoxic T lymphocyte antigen-4 expression in esophageal carcinoma: implications for prognosis. Oncotarget 7(18):26670-9, 2016. e-Pub 2016. PMID: 27050369.
- Chen CL, Wang Y, Pan QZ, Tang Y, Wang QJ, Pan K, Huang LX, He J, Zhao JJ, Jiang SS, Zhang XF, Zhang HX, Zhou ZQ, Weng de S, Xia JC. Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma. Oncotarget 7(13):16248-61, 2016. e-Pub 2016. PMID: 26919247.
- Zhang XF, Pan QZ, Pan K, Weng DS, Wang QJ, Zhao JJ, He J, Liu Q, Wang DD, Jiang SS, Zheng HX, Lv L, Chen CL, Zhang HX, Xia JC. Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma. Mol Carcinog 55(1):64-76, 2016. e-Pub 2016. PMID: 25557723.
- Jiang SS, Weng DS, Jiang L, Zhang YJ, Pan K, Pan QZ, Chen CL, Zhao JJ, Zhang XF, Zhang HX, Tang Y, Zhou ZQ, Chen MS, Xia JC. The clinical significance of preoperative serum cholesterol and high-density lipoprotein-cholesterol levels in hepatocellular carcinoma. J Cancer 7(6):626-32, 2016. e-Pub 2016. PMID: 27076843.
- Zhang XF, Chao J, Pan QZ, Pan K, Weng DS, Wang QJ, Zhao JJ, He J, Liu Q, Jiang SS, Chen CL, Zhang HX, Xia JC. Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma. Oncotarget 6(38):40920-33, 2015. e-Pub 2015. PMID: 26506518.
- Jiang SS, Tang Y, Zhang YJ, Weng DS, Zhou ZG, Pan K, Pan QZ, Wang QJ, Liu Q, He J, Zhao JJ, Li J, Chen MS, Chang AE, Li Q, Xia JC. A phase I clinical trial utilizing autologous tumor-infiltrating lymphocytes in patients with primary hepatocellular carcinoma. Oncotarget 6(38):41339-49, 2015. e-Pub 2015. PMID: 26515587.
- Jiang SS, Li JJ, Li Y, He LJ, Wang QJ, Weng DS, Pan K, Liu Q, Zhao JJ, Pan QZ, Zhang XF, Tang Y, Chen CL, Zhang HX, Xu GL, Zeng YX, Xia JC. A novel pathogenic germline mutation in the adenomatous polyposis coli gene in a Chinese family with familial adenomatous coli. Oncotarget 6(29):27267-74, 2015. e-Pub 2015. PMID: 26311738.
- Pan QZ, Pan K, Weng DS, Zhao JJ, Zhang XF, Wang DD, Lv L, Jiang SS, Zheng HX, Xia JC. Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma. Mol Carcinog 54(8):598-607, 2015. e-Pub 2015. PMID: 24375474.
- Pan QZ, Wang QJ, Dan JQ, Pan K, Li YQ, Zhang YJ, Zhao JJ, Weng DS, Tang Y, Huang LX, He J, Chen SP, Ke ML, Chen MS, Wicha MS, Chang AE, Zeng YX, Li Q, Xia JC. A nomogram for predicting the benefit of adjuvant cytokine-induced killer cell immunotherapy in patients with hepatocellular carcinoma. Sci Rep 5:9202, 2015. e-Pub 2015. PMID: 25776856.
- Pan QZ, Pan K, Wang QJ, Weng DS, Zhao JJ, Zheng HX, Zhang XF, Jiang SS, Lv L, Tang Y, Li YQ, He J, Liu Q, Chen CL, Zhang HX, Xia JC. Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells. Stem Cells 33(2):354-66, 2015. e-Pub 2015. PMID: 25267273.
- Li Y, Pan K, Liu LZ, Li YQ, Gu MF, Zhang H, Shen WX, Xia JC, Li JJ. Sequential Cytokine-Induced Killer Cell Immunotherapy Enhances the Efficacy of the Gemcitabine Plus Cisplatin Chemotherapy Regimen for Metastatic Nasopharyngeal Carcinoma. PLoS One 10(6):e0130620, 2015. e-Pub 2015. PMID: 26098948.
- Li JJ, He LJ, Luo GY, Liu LZ, Huang XX, Pan K, Xu GL. Fine-needle aspiration of a retropharyngeal lymph node guided by endoscopic ultrasonography. Endoscopy 47 Suppl 1 UCTN:E449-50, 2015. e-Pub 2015. PMID: 26465178.
- Jiang SS, Weng DS, Wang QJ, Pan K, Zhang YJ, Li YQ, Li JJ, Zhao JJ, He J, Lv L, Pan QZ, Xia JC. Galectin-3 is associated with a poor prognosis in primary hepatocellular carcinoma. J Transl Med 12:273, 2014. e-Pub 2014. PMID: 25260879.
- Wang H, Jiang S, Zhang Y, Pan K, Xia J, Chen M. High expression of thymosin beta 10 predicts poor prognosis for hepatocellular carcinoma after hepatectomy. World J Surg Oncol 12:226, 2014. e-Pub 2014. PMID: 25037578.
- Mai C, Zhao JJ, Tang XF, Wang W, Pan K, Pan QZ, Zhang XF, Jiang SS, Zhao BW, Li YF, Xia JC, Zhou ZW. Decreased ITIH5 expression is associated with poor prognosis in primary gastric cancer. Med Oncol 31(7):53, 2014. e-Pub 2014. PMID: 24913813.
- Zhao JJ, Pan QZ, Pan K, Weng DS, Wang QJ, Li JJ, Lv L, Wang DD, Zheng HX, Jiang SS, Zhang XF, Xia JC. Interleukin-37 mediates the antitumor activity in hepatocellular carcinoma: role for CD57+ NK cells. Sci Rep 4:5177, 2014. e-Pub 2014. PMID: 24898887.
- Pan K, Guan XX, Li YQ, Zhao JJ, Li JJ, Qiu HJ, Weng DS, Wang QJ, Liu Q, Huang LX, He J, Chen SP, Ke ML, Zeng YX, Xia JC. Clinical activity of adjuvant cytokine-induced killer cell immunotherapy in patients with post-mastectomy triple-negative breast cancer. Clin Cancer Res 20(11):3003-11, 2014. e-Pub 2014. PMID: 24668644.
- Pan K, Lv L, Zheng HX, Zhao JJ, Pan QZ, Li JJ, Weng DS, Wang DD, Jiang SS, Chang AE, Li Q, Xia JC. OK-432 synergizes with IFN-gamma to confer dendritic cells with enhanced antitumor immunity. Immunol Cell Biol 92(3):263-74, 2014. e-Pub 2014. PMID: 24296809.
- Pan K, Wang QJ, Liu Q, Zheng HX, Li YQ, Weng DS, Li JJ, Huang LX, He J, Chen SP, Ke ML, Zeng YX, Xia JC. The phenotype of ex vivo generated cytokine-induced killer cells is associated with overall survival in patients with cancer. Tumour Biol 35(1):701-7, 2014. e-Pub 2014. PMID: 23955802.
- Zheng Y, Wang DD, Wang W, Pan K, Huang CY, Li YF, Wang QJ, Yuan SQ, Jiang SS, Qiu HB, Chen YM, Zhang XF, Zhao BW, Mai C, Xia JC, Zhou ZW. Reduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients. PLoS One 9(4):e93073, 2014. e-Pub 2014. PMID: 24698999.
- Pan K, Li YQ, Wang W, Xu L, Zhang YJ, Zheng HX, Zhao JJ, Qiu HJ, Weng DS, Li JJ, Wang QJ, Huang LX, He J, Chen SP, Ke ML, Wu PH, Chen MS, Li SP, Xia JC, Zeng YX. The efficacy of cytokine-induced killer cell infusion as an adjuvant therapy for postoperative hepatocellular carcinoma patients. Ann Surg Oncol 20(13):4305-11, 2013. e-Pub 2013. PMID: 23892527.
- Zhang F, Sun XF, Li YQ, Zhen ZJ, Zheng HX, Zhu J, Wang QJ, Lu SY, He J, Wang J, Pan K, Cai RQ, Chen Y, Weng DS, Sun FF, Xia JC. Safety of in vitro amplified HLA-haploidentical donor immune cell infusions for childhood malignancies. Chin J Cancer 32(12):661-6, 2013. e-Pub 2013. PMID: 23706769.
- Pan QZ, Pan K, Zhao JJ, Chen JG, Li JJ, Lv L, Wang DD, Zheng HX, Jiang SS, Zhang XF, Xia JC. Decreased expression of interleukin-36alpha correlates with poor prognosis in hepatocellular carcinoma. Cancer Immunol Immunother 62(11):1675-85, 2013. e-Pub 2013. PMID: 24061617.
- Lu L, Pan K, Zheng HX, Li JJ, Qiu HJ, Zhao JJ, Weng DS, Pan QZ, Wang DD, Jiang SS, Chang AE, Li Q, Xia JC. IL-17A promotes immune cell recruitment in human esophageal cancers and the infiltrating dendritic cells represent a positive prognostic marker for patient survival. J Immunother 36(8):451-8, 2013. e-Pub 2013. PMID: 23994890.
- Zhao JJ, Pan K, Wang QJ, Xu ZD, Weng DS, Li JJ, Li YQ, Xia JC. Effect of anti-asthma Chinese medicine Chuankezhi on the anti-tumor activity of cytokine-induced killer cells. Chin J Cancer 32(10):553-60, 2013. e-Pub 2013. PMID: 23470144.
- Li JJ, Pan K, Gu MF, Chen MS, Zhao JJ, Wang H, Liang XT, Sun JC, Xia JC. Prognostic value of soluble MICA levels in the serum of patients with advanced hepatocellular carcinoma. Chin J Cancer 32(3):141-8, 2013. e-Pub 2013. PMID: 22704489.
- Huang CY, Zhao JJ, Lv L, Chen YB, Li YF, Jiang SS, Wang W, Pan K, Zheng Y, Zhao BW, Wang DD, Chen YM, Yang L, Zhou ZW, Xia JC. Decreased expression of AZGP1 is associated with poor prognosis in primary gastric cancer. PLoS One 8(7):e69155, 2013. e-Pub 2013. PMID: 23935945.
- Huang CY, Chen YM, Zhao JJ, Chen YB, Jiang SS, Yan SM, Zhao BW, Pan K, Wang DD, Lv L, Li YF, Wang W, Zhou ZW, Xia JC. Decreased expression of transcription elongation factor A-like 7 is associated with gastric adenocarcinoma prognosis. PLoS One 8(1):e54671, 2013. e-Pub 2013. PMID: 23372750.
- Yang XB, Zhao JJ, Huang CY, Wang QJ, Pan K, Wang DD, Pan QZ, Jiang SS, Lv L, Gao X, Chen HW, Yao JY, Zhi M, Xia JC. Decreased expression of the FOXO3a gene is associated with poor prognosis in primary gastric adenocarcinoma patients. PLoS One 8(10):e78158, 2013. e-Pub 2013. PMID: 24194912.
- Chen Y, Pan K, Li S, Xia J, Wang W, Chen J, Zhao J, Lu L, Wang D, Pan Q, Wang Q, Li Y, He J, Li Q. Decreased expression of V-set and immunoglobulin domain containing 1 (VSIG1) is associated with poor prognosis in primary gastric cancer. J Surg Oncol 106(3):286-93, 2012. e-Pub 2012. PMID: 22095633.
- Pan K, Liang XT, Zhang HK, Zhao JJ, Wang DD, Li JJ, Lian Q, Chang AE, Li Q, Xia JC. Characterization of bridging integrator 1 (BIN1) as a potential tumor suppressor and prognostic marker in hepatocellular carcinoma. Mol Med 18(1):507-18, 2012. e-Pub 2012. PMID: 22281836.
- Li JJ, Gu MF, Pan K, Liu LZ, Zhang H, Shen WX, Xia JC. Autologous cytokine-induced killer cell transfusion in combination with gemcitabine plus cisplatin regimen chemotherapy for metastatic nasopharyngeal carcinoma. J Immunother 35(2):189-95, 2012. e-Pub 2012. PMID: 22306907.
- Zhao JJ, Pan K, Wang W, Chen JG, Wu YH, Lv L, Li JJ, Chen YB, Wang DD, Pan QZ, Li XD, Xia JC. The prognostic value of tumor-infiltrating neutrophils in gastric adenocarcinoma after resection. PLoS One 7(3):e33655, 2012. e-Pub 2012. PMID: 22442706.
- Wang DD, Chen YB, Pan K, Wang W, Chen SP, Chen JG, Zhao JJ, Lv L, Pan QZ, Li YQ, Wang QJ, Huang LX, Ke ML, He J, Xia JC. Decreased expression of the ARID1A gene is associated with poor prognosis in primary gastric cancer. PLoS One 7(7):e40364, 2012. e-Pub 2012. PMID: 22808142.
- Lv L, Pan K, Li XD, She KL, Zhao JJ, Wang W, Chen JG, Chen YB, Yun JP, Xia JC. The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma. PLoS One 6(3):e18219, 2011. e-Pub 2011. PMID: 21483813.
- Liang XT, Pan K, Chen MS, Li JJ, Wang H, Zhao JJ, Sun JC, Chen YB, Ma HQ, Wang QJ, Xia JC. Decreased expression of XPO4 is associated with poor prognosis in hepatocellular carcinoma. J Gastroenterol Hepatol 26(3):544-9, 2011. e-Pub 2011. PMID: 21332550.
- Ma H, Liang X, Chen Y, Pan K, Sun J, Wang H, Wang Q, Li Y, Zhao J, Li J, Chen M, Xia J. Decreased expression of BATF2 is associated with a poor prognosis in hepatocellular carcinoma. Int J Cancer 128(4):771-7, 2011. e-Pub 2011. PMID: 20473897.
- Wang W, Lv L, Pan K, Zhang Y, Zhao JJ, Chen JG, Chen YB, Li YQ, Wang QJ, He J, Chen SP, Zhou ZW, Xia JC. Reduced expression of transcription factor AP-2alpha is associated with gastric adenocarcinoma prognosis. PLoS One 6(9):e24897, 2011. e-Pub 2011. PMID: 21966377.
- Zhao JJ, Pan K, Li JJ, Chen YB, Chen JG, Lv L, Wang DD, Pan QZ, Chen MS, Xia JC. Identification of LZAP as a new candidate tumor suppressor in hepatocellular carcinoma. PLoS One 6(10):e26608, 2011. e-Pub 2011. PMID: 22028922.
- Pan K, Zhao JJ, Wang H, Li JJ, Liang XT, Sun JC, Chen YB, Ma HQ, Liu Q, Xia JC. Comparative analysis of cytotoxic T lymphocyte response induced by dendritic cells loaded with hepatocellular carcinoma -derived RNA or cell lysate. Int J Biol Sci 6(7):639-48, 2010. e-Pub 2010. PMID: 20975822.
- Sun JC, Liang XT, Pan K, Wang H, Zhao JJ, Li JJ, Ma HQ, Chen YB, Xia JC. High expression level of EDIL3 in HCC predicts poor prognosis of HCC patients. World J Gastroenterol 16(36):4611-5, 2010. e-Pub 2010. PMID: 20857535.
- Sun JC, Pan K, Chen MS, Wang QJ, Wang H, Ma HQ, Li YQ, Liang XT, Li JJ, Zhao JJ, Chen YB, Pang XH, Liu WL, Cao Y, Guan XY, Lian QZ, Xia JC. Dendritic cells-mediated CTLs targeting hepatocellular carcinoma stem cells. Cancer Biol Ther 10(4):368-75, 2010. e-Pub 2010. PMID: 20581468.
- Ma H, Weng D, Chen Y, Huang W, Pan K, Wang H, Sun J, Wang Q, Zhou Z, Wang H, Xia J. Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene. Mol Cancer 9:190, 2010. e-Pub 2010. PMID: 20626849.
- Wang QJ, Wang H, Pan K, Li YQ, Huang LX, Chen SP, He J, Ke ML, Zhao JJ, Li JJ, Sun JC, Liang XT, Ma HQ, Chen YB, Xia JC. Comparative study on anti-tumor immune response of autologous cytokine-induced killer (CIK) cells, dendritic cells-CIK (DC-CIK), and semi-allogeneic DC-CIK. Chin J Cancer 29(7):641-8, 2010. e-Pub 2010. PMID: 20591215.
- Ma H, Zhang Y, Wang Q, Li Y, He J, Wang H, Sun J, Pan K, Chen M, Xia J. Therapeutic safety and effects of adjuvant autologous RetroNectin activated killer cell immunotherapy for patients with primary hepatocellular carcinoma after radiofrequency ablation. Cancer Biol Ther 9(11):903-7, 2010. e-Pub 2010. PMID: 20364106.
- Zhang H, Ma H, Wang Q, Chen M, Weng D, Wang H, Zhou J, Li Y, Sun J, Chen Y, Liang X, Zhao J, Pan K, Wang H, Xia J. Analysis of loss of heterozygosity on chromosome 4q in hepatocellular carcinoma using high-throughput SNP array. Oncol Rep 23(2):445-55, 2010. e-Pub 2010. PMID: 20043106.
- Ma HQ, Liang XT, Zhao JJ, Wang H, Sun JC, Chen YB, Pan K, Xia JC. Decreased expression of Neurensin-2 correlates with poor prognosis in hepatocellular carcinoma. World J Gastroenterol 15(38):4844-8, 2009. e-Pub 2009. PMID: 19824122.
- Zhou J, Weng D, Zhou F, Pan K, Song H, Wang Q, Wang H, Wang H, Li Y, Huang L, Zhang H, Huang W, Xia J. Patient-derived renal cell carcinoma cells fused with allogeneic dendritic cells elicit anti-tumor activity: in vitro results and clinical responses. Cancer Immunol Immunother 58(10):1587-97, 2009. e-Pub 2009. PMID: 19221746.
- Pan K, Wang H, Liu WL, Zhang HK, Zhou J, Li JJ, Weng DS, Huang W, Sun JC, Liang XT, Xia JC. The pivotal role of p38 and NF-kappaB signal pathways in the maturation of human monocyte-derived dendritic cells stimulated by streptococcal agent OK-432. Immunobiology 214(5):350-8, 2009. e-Pub 2009. PMID: 19362680.
- Pan K, Wang H, Chen MS, Zhang HK, Weng DS, Zhou J, Huang W, Li JJ, Song HF, Xia JC. Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinoma. J Cancer Res Clin Oncol 134(11):1247-53, 2008. e-Pub 2008. PMID: 18438685.
- Huang W, Weng DS, Pan ZZ, Pan K, Ding PR, Zhou J, Wang H, Zhang HK, Li JJ, Xia JC. [Expression and clinical significance of TESTIN in primary gastric cancer]. Ai Zheng 27(9):984-8, 2008. e-Pub 2008. PMID: 18799041.
- Song HF, Zhou J, Pan K, Wang QJ, Wang H, Huang LX, Li YQ, Xia JC. [Antitumor effects and mechanisms of a dendritic cell vaccine which silenced SOCS1 by siRNA, stimulated by OK-432 and pulsed with lysate of HepG2 cells]. Ai Zheng 27(7):685-91, 2008. e-Pub 2008. PMID: 18606059.
- Wang H, Pan K, Zhang HK, Weng DS, Zhou J, Li JJ, Huang W, Song HF, Chen MS, Xia JC. Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma. J Cancer Res Clin Oncol 134(5):535-41, 2008. e-Pub 2008. PMID: 17917742.
- Yang J, Wang H, Jiang Y, Sun Y, Pan K, Lei H, Wu Q, Shen Y, Xiao Z, Xu Z. Development of an enzyme-linked immuno-sorbent assay (ELISA) method for carbofuran residues. Molecules 13(4):871-81, 2008. e-Pub 2008. PMID: 18463589.
- Zhang HK, Pan K, Wang H, Weng DS, Song HF, Zhou J, Huang W, Li JJ, Chen MS, Xia JC. Decreased expression of ING2 gene and its clinicopathological significance in hepatocellular carcinoma. Cancer Lett 261(2):183-92, 2008. e-Pub 2008. PMID: 18160212.
- Pan K, Wang H, Zhang HB, Liu HW, Lei HT, Huang L, Sun YM. Production and characterization of single chain Fv directed against beta2-agonist clenbuterol. J Agric Food Chem 54(18):6654-9, 2006. e-Pub 2006. PMID: 16939323.
Review Articles
- Chen JG, Xia JC, Liang XT, Pan K, Wang W, Lv L, Zhao JJ, Wang QJ, Li YQ, Chen SP, He J, Huang LX, Ke ML, Chen YB, Ma HQ, Zeng ZW, Zhou ZW, Chang AE, Li Q. Intratumoral expression of IL-17 and its prognostic role in gastric adenocarcinoma patients. Int J Biol Sci 7(1):53-60, 2011. e-Pub 2011. PMID: 21234303.
- Wang H, Pan K, Xia JC. Interaction of indoleamine-2,3-dioxyagnase and CD4+CD25+ regulatory T cells in tumor immune escape. Ai Zheng 28(2):184-7, 2009. e-Pub 2009. PMID: 19550135.
Patents
- Yee C, Pan K. HLA-restricted VCX/Y peptides and T cell receptors and use thereof, 2020. Patent Number: US11696933B2.
Patient Reviews
CV information above last modified March 06, 2026