Kelly S. Chien, M.D.
Department of Leukemia, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2013 | Baylor College of Medicine, Houston, TX, USA, MD, Doctorate of Medicine |
| 2008 | Massachusetts Institute of Technology, Cambridge, MA, USA, SB, Chemical Engineering |
| 2008 | Massachusetts Institute of Technology, Cambridge, MA, USA, SB, Biology |
Postgraduate Training
| 2019-2020 | Hematology Chief Fellow, Hematology/Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX |
| 2017-2019 | Clinical Fellowship, Hematology/Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX |
| 2014-2016 | Clinical Residency, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX |
| 2013-2014 | Clinical Internship, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX |
Board Certifications
| 2016 | American Board of Internal Medicine Certification |
Honors & Awards
| 2020 | Waun Ki Hong Award for Achievement in Clinical Investigation, University of Texas MD Anderson Cancer Center |
| 2020 | Kimberly Patterson Fellowship in Leukemia Research, University of Texas MD Anderson Cancer Center |
| 2019 | Conquer Cancer Foundation Young Investigator Award, American Society of Clinical Oncology |
| 2019 | Merit Award, American Society of Clinical Oncology Annual Meeting |
| 2019 | Oncology Fellows Program Participant, National Comprehensive Cancer Network Annual Meeting |
| 2018 | Abstract Achievement Award, American Society of Hematology Annual Meeting |
| 2016 | Internal Medicine Resident Teaching Award Honorable Mention, University of Texas Southwestern Medical Center |
| 2014 | Internal Medicine Intern Teaching Award Honorable Mention, University of Texas Southwestern Medical Center |
| 2008 | Top 5, MIT 6.270 Autonomous Robot Competition |
| 2004 | National Merit Scholar, National Merit Scholarship Program |
| 2004 | Semi-Finalist, Young Epidemiology Scholars Competition |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Chien KS, Ong F, Kim K, Li Z, Kanagal-Shamanna R, DiNardo CD, Takahashi K, Montalban-Bravo G, Hammond D, Sasaki K, Pierce SA, Kantarjian HM, Garcia-Manero G. Cancer patients with clonal hematopoiesis die from primary malignancy or comorbidities despite higher rates of transformation to myeloid neoplasms. Cancer Med 13(5):e7093, 2024. PMID: 38497538.
- Chien KS, Peterson CB, Young E, Chihara D, Manasanch EE, Ramdial JL, Thompson PA. Outcomes of Breakthrough COVID-19 Infections in Patients with Hematologic Malignancies. Blood Adv 7(19):5691-5697, 2023. e-Pub 2023. PMID: 36696472.
- Urrutia S, Chien KS, Li Z, Bataller A, Almanza E, Sasaki K, Montalban-Bravo G, Short NJ, Jabbour E, Kadia TM, Ravandi F, Borthakur G, Alvarado Y, Daver N, Kanagal-Shamanna R, Bueso-Ramos C, Pierce SA, Kantarjian H, Garcia-Manero G. Performance of IPSS-M in patients with myelodysplastic syndrome after hypomethylating agent failure. Am J Hematol 98(10):E281-E284, 2023. e-Pub 2023. PMID: 37515433.
- Bataller A, Chien KS, Sasaki K, Montalban-Bravo G, Kanagal-Shamanna R, Urrutia S, Almanza-Huante E, Gener-Ricos G, Ravandi F, Jabbour E, Kadia T, Borthakur G, Garcia-Manero G. PHF6 mutations in myelodysplastic syndromes, chronic myelomonocytic leukemia and acute myeloid leukemia. Leuk Res 127:107044, 2023. e-Pub 2023. PMID: 36801700.
- Chien KS, Kim K, Nogueras-Gonzalez GM, Borthakur G, Naqvi K, Daver NG, Montalban-Bravo G, Cortes JE, DiNardo CD, Jabbour E, Alvarado Y, Andreeff M, Bose P, Jain N, Kadia TM, Huang X, Sheppard KB, Klingner-Winton C, Pierce SA, Dong XQ, Soltysiak KA, Kantarjian HM, Garcia-Manero G. Phase II study of azacitidine with pembrolizumab in patients with intermediate-1 or higher-risk myelodysplastic syndrome. Br J Haematol 195(3):378-387, 2021. e-Pub 2021. PMID: 34340254.
- Garcia-Manero G, Chien KS, Montalban-Bravo G. Myelodysplastic Syndromes: 2021 update on Diagnosis, Risk-stratification and Management. Am J Hematol 95(11):1399-1420, 2020. e-Pub 2020. PMID: 32744763.
- Chien KS, Class CA, Montalban-Bravo G, Wei Y, Sasaki K, Naqvi K, Ganan-Gomez I, Yang H, Soltysiak KA, Kanagal-Shamanna R, Do KA, Kantarjian HM, Garcia-Manero G. LILRB4 expression in chronic myelomonocytic leukemia and myelodysplastic syndrome based on response to hypomethylating agents. Leuk Lymphoma 61(6):1493-1499, 2020. e-Pub 2020. PMID: 32036728.
- Montalban-Bravo G, Class CA, Ganan-Gomez I, Kanagal-Shamanna R, Sasaki K, Richard-Carpentier G, Naqvi K, Wei Y, Yang H, Soltysiak KA, Chien K, Bueso-Ramos C, Do KA, Kantarjian H, Garcia-Manero G. Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes. Leukemia 34(3):872-881, 2020. e-Pub 2019. PMID: 31719677.
- Montalban-Bravo G, Kanagal-Shamanna R, Benton CB, Class CA, Chien KS, Sasaki K, Naqvi K, Alvarado Y, Kadia TM, Ravandi F, Daver N, Takahashi K, Jabbour E, Borthakur G, Pemmaraju N, Konopleva M, Soltysiak KA, Pierce SR, Bueso-Ramos CE, Patel KP, Kantarjian H, Garcia-Manero G. Genomic context and TP53 allele frequency define clinical outcomes in TP53-mutated myelodysplastic syndromes. Blood Adv 4(3):482-495, 2020. PMID: 32027746.
- Benton CB, Chien KS, Tefferi A, Rodriguez J, Ravandi F, Daver N, Jabbour E, Jain N, Alvarado Y, Kwari M, Pierce S, Maiti A, Hornbaker M, Santos MA, Martinez S, Siguero M, Zblewski D, Al-Kali A, Hogan WJ, Kantarjian H, Pardanani A, Garcia-Manero G. Safety and tolerability of lurbinectedin (PM01183) in patients with acute myeloid leukemia and myelodysplastic syndrome. Hematol Oncol 37(1):96-102, 2019. e-Pub 2018. PMID: 30153704.
- Carvour ML, Ayyar BK, Chien KS, Ramirez NC, Yamamoto H. A Patient-Centered Approach to Postgraduate Trainee Health and Wellness: An Applied Review and Health Care Delivery Model. Acad Med 91(9):1205-10, 2016. PMID: 27415444.
- Pandey A, Sarangi S, Chien K, Sengupta P, Papa AL, Basu S, Sengupta S. Anti-platelet agents augment cisplatin nanoparticle cytotoxicity by enhancing tumor vasculature permeability and drug delivery. Nanotechnology 25(44):445101, 2014. e-Pub 2014. PMID: 25302488.
- Farmakiotis D, Chien KS, Shum TC, Rodriguez-Barradas M, Musher DM. Photo quiz. To scan or not to scan?. Clin Infect Dis 56(7):1003, 1052-3, 2013. PMID: 23463794.
Abstracts
- Chien KS, Class CA, Montalban-Bravo G, Sasaki K, Naqvi K, Ganan-Gomez I, Wei Y, Yang H, Kanagal-Shamanna R, Soltysiak KA, Kantarjian HM, Garcia-Manero G. LILRB4 Expression in CMML and MDS Based on Response to Hypomethylating Agents, 2019.
Letters to the Editor
- Chien KS, Farmakiotis D, Rodriguez-Barradas MC, Musher DM. It's not that simple. Clin Infect Dis 56: 308, 2013.
Grant & Contract Support
| Title: | Prevention of Therapy-Related Myeloid Neoplasms with Clonal Hematopoiesis of Indeterminate Potential |
| Funding Source: | American Society of Clinical Oncology (ASCO) |
| Role: | Principal Investigator |
| Title: | |
| Funding Source: | NIH/NCI |
| Role: | Trainee |
Patient Reviews
CV information above last modified July 12, 2024