Meet Keri Schadler, Ph.D.
KERI SCHADLER, PhD
Department of Pediatrics, Division of Pediatrics
Present Title & Affiliation
Primary Appointment
Director of Laboratory Research, Department of Pediatrics - Research, Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas
Special Assistant to Vice President of Education and Training, The University of Texas MD Anderson Cancer Center, Houston, Texas
Tenured Associate Professor, Department of Pediatrics - Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2010 | The University of Texas MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, Texas, US, Ph.D. in Cancer Biology |
| 2004 | Texas A & M University, College Station, Texas, US, BS in Molecular and Cell Biology |
Postgraduate Training
| 2010-2014 | Research Fellowship, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania |
Experience & Service
Faculty Academic Appointments
Assistant Professor, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2016 - 2022
Extramural Institutional Committee Activities
Chair, International Society of Exercise Oncology Scientific Organizing Committee, International Society of Exercise Oncology (ISEO), 2026
Director, Odysssey Fellowship, The University of Texas MD Anderson Cancer Center, 2023 - Present
Community Outreach and Engagement Representative, CCSG Cancer Biology and Metastasis Research Program, The University of Texas MD Anderson Cancer Center, 2022 - Present
Co-chair and Co-creator, Functional Mentoring Program, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Committee Chair, Jr Faculty Committee, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Member, Career Tracks Task Force, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Member, Vice President's Population Sciences Advisory Committee, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Past Chair, Jr Faculty Committee, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Chair-Elect, Jr Faculty Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2019
Team Leader, Pediatrics Energy Balance & Integrative Medicine Multidisciplinary Team, The University of Texas MD Anderson Cancer Center, 2017 - Present
Member, Jr Faculty Committee, The University of Texas MD Anderson Cancer Center, 2017 - 2018
Honors & Awards
| 2021 | President's Recognition of Faculty Excellence, Prevention Outreach Honoree, University of Texas MD Anderson Cancer Center |
| 2020 | Fellow, Transdisciplinary Research on Energetics and Cancer Consortium, NCI |
| 2018 | President's Research Excellence Award, MD Anderson Cancer Center |
| 2016 | Best Poster in the Faculty Poster Category, MD Anderson Cancer Center/Energy Balance and Cancer Research Retreat |
| 2016 | Selected Participant - AAMC Leadership and Management Foundations for Academic Medicine and Science 2016 |
| 2014 | 2014 Best Oral Presentation, The Abramson Family Cancer Research Institute Cancer Biology Trainee Seminar Series University of Pennsylvania |
| 2014 | Fellow, NIH T32 Training Program, Immunobiology of Normal and Neoplastic Lymphocytes, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA |
| 2014 | Fellow, Penn Transdisciplinary Research on Energetics and Cancer Consortium, University of Pennsylvania, Philadelphia, PA |
| 2014 | Fellow, Union for International Cancer Control, University of Tokyo Komaba, Tokyo, Japan, 2014 |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2025. Keynote Lecture: Navigating your career in turbulent times. Invited. Graduate Careers Symposium. Houston, Texas, US.
- 2025. Cancer Rehabilitation Conference 2025. Invited. Houston, Texas, US.
- 2025. MD Anderson Integrative Medicine Grand Rounds. Invited. Houston, Texas, US.
- 2024. Excercise may be a Novel Strategy to Reduce ICI-associated Vascular Toxicity in a Mouse Melanoma Model. Poster. Cancer Survivorship Research Retreat. Houston, Texas, US.
- 2024. Exercise induced changes in the tumor microenvironment. MIB Agents. Houston, Texas, US.
- 2021. Vascular normalization: a re-emerging concept & Exercise: a novel method to achieve it. Conference. Vascular normalization: a re-emerging concept & Exercise: a novel method to achieve it. Houston, TX, US.
- 2019. Novel methods of tumor vascular remodeling to improve chemotherapy efficacy. Houston, Texas, US.
- 2019. Novel mediators of tumor vascular remodeling. Houston, Texas, US.
- 2018. Identifying the molecular regulators of tumor vascular remodeling in response to exercise. The Brown Foundation Institute of Molecular Medicine for the Prevention of Diseases. Houston, Texas, US.
- 2018. Exercise To Improve Chemotherapy Efficacy Against Solid Tumors Contemporary Issues: Exercise in Medicine Seminar Series. Houston, Texas, US.
- 2018. Mechanisms of aerobic exercise induced vessel remodeling in Ewing sarcoma. Conference. Mechanisms of aerobic exercise induced vessel remodeling in Ewing sarcoma. Houston, TX, US.
- 2018. Exercise Improves Chemotherapy Delivery in Ewing Sarcoma by Decreasing Vessel Permeability. Conference. Exercise Improves Chemotherapy Delivery in Ewing Sarcoma by Decreasing Vessel Permeability. Houston, TX, US.
- 2017. Moderate exercise to improve chemotherapy delivery for pancreas cancer: a team effort from mice to patients. Conference. Moderate exercise to improve chemotherapy delivery for pancreas cancer: a team effort from mice to patients. Houston, TX, US.
- 2016. Vascular normalization to improve drug delivery in mouse models of Ewing's sarcoma. Conference. Vascular normalization to improve drug delivery in mouse models of Ewing's sarcoma. Houston, TX, US.
- 2016. Solid tumor vascular biology and chemotherapy delivery. Conference. Solid tumor vascular biology and chemotherapy delivery. Houston, TX, US.
- 2016. Exercise improves chemotherapy delivery and efficacy by normalizing tumor vasculature. Conference. Exercise improves chemotherapy delivery and efficacy by normalizing tumor vasculature. Houston, TX, US.
- 2015. Exercise causes tumor vascular normalization: Better vessels for better chemotherapy delivery. Conference. Exercise causes tumor vascular normalization: Better vessels for better chemotherapy delivery. Houston, TX, US.
- 2015. A little exercise goes a long way to deliver chemotherapy. Conference. The Center for Energy Balance in Cancer Prevention and Survivorship. Houston, TX, US.
- 2001. Developing your niche in biomedical research. ITERT: Interdisciplinary Translational Education and Research Training Program. Houston, Texas, US.
Regional Presentations
- 2022. Exercise modulates the PDAC tumor microenvironment to improve chemotherapeutic efficacy. Department of Kinesiology Seminar Series. College Station, Texas, US.
- 2018. Sphingosine-1-Phosphate Receptor 2 Modulation through Exercise to Improve Chemotherapy Efficacy in Ewing Sarcoma. Conference. Sphingosine-1-Phosphate Receptor 2 Modulation through Exercise to Improve Chemotherapy Efficacy in Ewing Sarcoma. College Station, TX, US.
- 2018. The effects of sheer stress on endothelial to tumor cell crosstalk in Ewing Sarcoma. Conference. The effects of sheer stress on endothelial to tumor cell crosstalk in Ewing Sarcoma. College Station, TX, US.
- 2018. S1P receptors as mediators of tumor vascular response to exercise. Conference. S1P receptors as mediators of tumor vascular response to exercise. College Station, TX, US.
- 2016. Vessel normalization and chemotherapy efficacy: better blood vessels for better drug delivery. Grand Rounds. San Antonio, Texas, US.
National Presentations
- 2026. Prospective Multi-Center Study of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and/or Multi-Organ Dysfunction Syndrome (POEM Interim Analysis):Baseline Levels of Circulating Angiogenic Factors May Predict Risk of Sinusoidal Obstructive Syndrome) . Poster. Transplantation & Cellular Therapy Meeting of ASTCT and CIBMTR Tandem Meetings. Salt Lake City, Utah, US.
- 2024. Exercise reduces pancreatic tumor growth in a gut microbiome dependent manner. Poster. Sumedha Pareek. Boston, MA, US.
- 2024. Aerobic exercise decreases glucose metabolism in melanoma. Poster. Jonghae Lee. New Orleans, LA, US.
- 2024. Exercise may prevent immune checkpoint inhibitor-associated vascular toxicity. Invited. Jonghae Lee. Houston, TX, US.
- 2024. Understanding The Role of Exercise in Lymphatic Vessel Regulation in Melanoma and Utilizing Preclinical Models to Inform Clinical Exercise Oncology. Conference. ACSM Annual Meeting. Boston, Massachusetts, US.
- 2023. Learning from mouse models of exercise and cancer. Invited. Cardio-Oncology Seminar Series. Milwaukee, Wisconsin, US.
- 2023. President’s Symposium: Exercise regulation of the melanoma immune microenvironment. Invited. Presidential Symposium, CO, US.
- 2023. Exercise changes the tumor and may improve therapeutic response. Invited. Complementary Cancer Care: A Physical Health Perspective, MD, US.
- 2022. Exercise as a master regulator of the tumor microenvironment. Invited. Nutrition Obesity Research Center. Birmingham, Alabama, US.
- 2022. Mouse Models Combining Exercise and Immune Checkpoint Blockade to Treat Cancer. Conference. Mouse Models Combining Exercise and Immune Checkpoint Blockade to Treat Cancer. San Diego, CA, US.
- 2022. Perspectives on Cancer and Aging: Arti Hurria Memorial Webinar Series. Bethesda, Maryland, US.
- 2021. Exercise improves tumor vascular function to enhance chemotherapy in mice. Conference. Exercise improves tumor vascular function to enhance chemotherapy in mice. Virtual, US.
- 2021. Potential mechanisms regulating exercise-induced tumor vascular normalization. Invited. Hershey, Pennsylvania, US.
- 2021. Exercise modulation of tumor microenvironment as an adjuvant to standard therapies. Invited. Cancer Control and Survivorship Program Seminar Series, US.
- 2021. The endothelium as a target of transplant related injury. Conference. American Society of Pediatric Hematology and Oncology Annual Conference, US.
- 2020. Tumor growth reduced and tumor-infiltrating lymphocytes increased with exercise training in mouse model of pancreatic cancer. Conference. Tumor growth reduced and tumor-infiltrating lymphocytes increased with exercise training in mouse model of pancreatic cancer. Online, US.
- 2020. Exercise as a novel mediator of Ewing sarcoma tumor vascular modulation. Conference. 2020 CPRIT Innovations in Cancer Prevention and Research Conference. Austin, TX, US.
- 2020. Exercise Impacts Tumor Biology and Drug Efficacy. Conference. American College of Sports Medicine Annual Meeting. Cancelled due to COVID-19, US.
- 2019. The Role of the ERK5 axis in aerobic exercise induced tumor vascular remodeling. Conference. The Role of the ERK5 axis in aerobic exercise induced tumor vascular remodeling. Monterey, CA, US.
- 2019. Exercise remodels tumor vasculature. Conference. Exercise remodels tumor vasculature. Virtual Conference, Twitter, #ExOncTC, US.
- 2019. Moderate Exercise: A Novel Method to Improve Tumor Vascular Function for Improved Treatment Efficacy. Conference. Northwestern Mutual for the MACC Fund Center for Cancer and Blood Disorders. Milwaukee, WI, US.
- 2019. Exercise is associated with skeletal muscle preservation during preoperative treatment of pancreatic cancer. Conference. Exercise is associated with skeletal muscle preservation during preoperative treatment of pancreatic cancer, US.
- 2019. Endothelial Signaling Pathways of Interest for VOD. Conference. Endothelial Signaling Pathways of Interest for VOD. Houston, TX, US.
- 2019. Exercise to Remodel Tumor Vasculature: Current Data and Extrapolations Toward Treatment-Associated Aging. National Institutes of Health. Rockville, Maryland, US.
- 2018. Evidence for exercise to improve chemotherapy efficacy. Distinguished Lecture Series. Manhattan, Kansas, US.
- 2018. Exercise to Improve Drug Delivery: From Mice to Patients. Conference. COG State-of-the-Science Nutrition Meeting. Dallas, TX, US.
- 2018. Exercise To Improve Chemotherapy Efficacy Against Solid Tumors: Evidence in Mice and Men. Hanover, New Hampshire, US.
- 2018. Vascular Remodeling to Improve Chemotherapy Delivery to Ewing Tumors. Conference. Children's Oncology Group. Houston, TX, US.
- 2018. Exercise Increases Pancreas Tumor Vascularity and Chemotherapy Delivery. Conference. Exercise Increases Pancreas Tumor Vascularity and Chemotherapy Delivery. Chicago, IL, US.
- 2018. Do social support and neighborhood walkability influence physical activity among patients undergoing preoperative therapy for pancreatic cancer?. Conference. Do social support and neighborhood walkability influence physical activity among patients undergoing preoperative therapy for pancreatic cancer?, US.
- 2018. Vascular Permeability and CRES: An Early Concept Proposal. Conference. Vascular Permeability and CRES: An Early Concept Proposal. San Diego, CA, US.
- 2018. Physical activity is associated with improved quality of life and functional fitness among patients receiving preoperative therapy for pancreatic cancer. Conference. Physical activity is associated with improved quality of life and functional fitness among patients receiving preoperative therapy for pancreatic cancer. New York, NY, US.
- 2017. Exercise Impacts Tumor Vasculature and Metastasis in Ewing Sarcoma. Conference. Connective Tissue Oncology Society Annual Meeting. Maui, HI, US.
- 2017. Sphingosine 1 Phosphate Receptors mediate tumor vascular normalization by exercise. Conference. Sphingosine 1 Phosphate Receptors mediate tumor vascular normalization by exercise. Santa Fe, NM, US.
- 2016. Increasing Chemotherapeutic efficacy via aerobic exercise. Conference. Susan G. Komen Foundation. New Orleans, LA, US.
- 2016. A Combination Approach Targeting Osteosarcoma Cells In-Vitro Using IL-11Ra CAR T-Cells with Anti-PD-1 Blockade. Conference. A Combination Approach Targeting Osteosarcoma Cells In-Vitro Using IL-11Ra CAR T-Cells with Anti-PD-1 Blockade. Minneapolis, MN, US.
- 2016. Increasing Chemotherapeutic Efficacy through Aerobic Exercise. Conference. National Cancer Institute. Rockville, MD, US.
- 2013. Shear Stress Normalizes Tumor Vasculature to Enhance Drug Delivery. Conference. Shear Stress Normalizes Tumor Vasculature to Enhance Drug Delivery. La Jolla, CA, US.
- 2012. Immune Suppression of Tumor Growth by Secretion of the Angiogenesis Inhibitor Thrombospondin-1. Conference. Immune Suppression of Tumor Growth by Secretion of the Angiogenesis Inhibitor Thrombospondin-1. Bethesda, MD, US.
- 2011. Determining the role of the NFAT regulator DYRK1A in Acute Megakaryoblastic Leukemia. Conference. Determining the role of the NFAT regulator DYRK1A in Acute Megakaryoblastic Leukemia. Philadelphia, PA, US.
- 2008. DLL4 is critical for BM-derived pericyte formation in Ewing's sarcoma vasculogenesis. Conference. DLL4 is critical for BM-derived pericyte formation in Ewing's sarcoma vasculogenesis. La Jolla, CA, US.
International Presentations
- 2026. Adapting a MIND diet score and its relationship with psychoneurological symptoms in childhood cancer survivors. Invited. MASCC/ISOO Annual Meeting, US.
- 2026. Exercise impacts the tumor microenvironment and response to therapy. Invited. Pediatric Exercise Oncology Congress (PEOC) x FORTE, DE.
- 2025. Moving Beyond Cancer. Invited. Lisbon, PT.
- 2024. Exercise mediated changes in the melanoma immune microenvironment. Invited. New Orleans, US.
- 2023. Prehabilitation for patients with pancreatic cancer. Ontario, CA.
- 2023. Let’s keep them going – Prehabilitation for pancreatic cancer from bench to clinic. Prehabilitation Rounds. Ontario, CA.
- 2022. Different Effects of Exercise on the Immune Response to Two Melanoma Models. Conference. Tuscan, US.
- 2020. Exercise Improves Tumor Vasculature Function via S1P Receptor Signaling. Conference. Seoul, KR.
- 2016. Tumor vessel normalization through exercise enhances chemotherapeutic efficacy. Conference. Boston, US.
- 2015. Tumor Vessel Normalization through Increased Shear Stress by Exercise Enhances Chemotherapeutic Efficacy. Conference. Tumor Vessel Normalization through Increased Shear Stress by Exercise Enhances Chemotherapeutic Efficacy. Tel Aviv, IL.
- 2015. Increasing shear stress to enhance delivery and efficacy of chemotherapy. Conference. Increasing shear stress to enhance delivery and efficacy of chemotherapy. Paris, FR.
- 2014. Exercise-induced shear stress normalizes tumor vasculature. Conference. Exercise-induced shear stress normalizes tumor vasculature. Kyoto, JP.
Grant & Contract Support
| Date: | 2026 - 2030 |
| Title: | AMBIENT: A Mind Body Intervention to Ease Neoplastic Treatment Toxicity |
| Funding Source: | NIH |
| Role: | Co-PI |
| ID: | GRANT14590431 |
| Date: | 2026 - 2028 |
| Title: | Novel methods to target macrophages for the treatment of Melanoma |
| Funding Source: | NIH |
| Role: | PI |
| ID: | GRANT14462503 |
| Date: | 2026 - Present |
| Title: | DDIAS as a hub for endothelial protection against radiation injury |
| Funding Source: | NIH |
| Role: | PI |
| ID: | GRANT14572054 |
| Date: | 2026 - Present |
| Title: | Exercise suppression of glycolysis may enhance the response of Ewing sarcoma lung metastases to existing therapies |
| Funding Source: | Ewing’s Sarcoma Research Grant |
| Role: | PI |
| Date: | 2025 - 2030 |
| Title: | Mechanisms of improved vascular function by exercise |
| Funding Source: | NIH |
| Role: | PI |
| ID: | Grant14347925 |
| Date: | 2025 - 2026 |
| Title: | Hirshberg Foundation for Pancreatic Cancer Research |
| Funding Source: | Seed Grant Program |
| Role: | PI |
| ID: | FP00027627 |
| Date: | 2025 - 2029 |
| Title: | Tele-PancFit: Impact of video supervised exercise for patients with resectable pancreatic cancer on tumor immune cell infiltration |
| Funding Source: | CPRIT |
| Role: | PI |
| ID: | RP250383 |
| Date: | 2024 - 2026 |
| Title: | Tele-PancFit: Impact of video supervised exercise for patients with resectable pancreatic cancer on tumor immune cell infiltration NIH/NCI, R2114066400 |
| Funding Source: | R21 |
| Role: | Co-I |
| ID: | GRANT14066400 |
| Date: | 2024 - 2026 |
| Title: | Virtually Delivered Home-based Exercise Intervention on Cognitive Impairment and Gut Microbiome in Adolescent and Young Adult Brain Tumor Survivors: A Pilot Randomized Controlled Trial |
| Funding Source: | Rise |
| Role: | Co-PI |
| Date: | 2024 - 2028 |
| Title: | The Academy at MD Anderson UTHealth Houston Graduate School - Maximizing Opportunities for Training, Development, and Community |
| Funding Source: | MD Anderson UTHealth Houston Graduate School |
| Role: | Collaborator |
| ID: | 1T32GM152796-01 |
| Date: | 2023 - 2028 |
| Title: | Medical Students Summer in Oncology at Anderson Research (Med Students SOAR) program |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | 1 R25 CA265800-01A1 |
| Date: | 2023 - 2024 |
| Title: | Effect of Exercise on The Pancreatic Cancer Microenvironment |
| Funding Source: | The Center for Energy Balance in Cancer Prevention and Survivorship |
| Role: | PI |
| Date: | 2022 - 2023 |
| Title: | Exercise as an adjuvant to ICB therapy for PDAC |
| Funding Source: | University Cancer Foundation IRG |
| Role: | PI |
| Date: | 2022 - 2024 |
| Title: | Assessing the tumor-specific metabolic effects of exercise in melanoma |
| Funding Source: | NIH/NCI |
| Role: | Project Leader |
| ID: | NCI 5P50CA221703-04 |
| Date: | 2022 - 2023 |
| Title: | The University of Texas MD Anderson Cancer Center SPORE |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 5P50CA221703-04 |
| Date: | 2021 - 2022 |
| Title: | Exercise May Reduce Immunosuppression in the Pancreatic Ductal Adenocarcinoma Tumor Microenvironment |
| Funding Source: | Pauline Altman-Goldstein Foundation Discovery Fellowship |
| Role: | Mentor |
| Date: | 2021 - 2022 |
| Title: | DCPPS: Admin Supplements for CCSGs to support research to understand and address organizational factors that contribute to disparities in outcomes among childhood cancer survivors |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | P30 CA016672 |
| Date: | 2020 - 2022 |
| Title: | Exercise modulation of NK cells in osteosarcoma |
| Funding Source: | Tri Delta Foundation |
| Role: | PI |
| Date: | 2020 - 2021 |
| Title: | Aerobic exercise as a novel method to remodel tumor vasculature and increase therapeutic efficacy |
| Funding Source: | The Schissler Foundation Fellowship |
| Role: | Mentor |
| Date: | 2020 - 2022 |
| Title: | Conference Proposal: Translating Energy Balance from Bench to Communities: Parallel Animal and Human Studies |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | R13 CA254014 |
| Date: | 2019 - 2022 |
| Title: | S1PR1 signaling in Ewing sarcoma tumor vasculature |
| Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
| Role: | PI |
| ID: | CA181287 |
| Date: | 2019 - 2020 |
| Title: | Mechanisms of aerobic exercise induced tumor vascular remodeling |
| Funding Source: | CPRIT Graduate Scholars Research Training Program RP170067 |
| Role: | Mentor |
| Date: | 2019 - 2022 |
| Title: | Role of S1PR1 in exercise-induced tumor vascular remodeling |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | CPRIT RP190256 |
| Date: | 2018 - 2020 |
| Title: | Energy Balance Strategies for Decreasing Chemotherapy-Induced Cardiotoxicity |
| Funding Source: | Alex’s Lemonade Stand Foundation |
| Role: | CO-I |
| Date: | 2018 - 2020 |
| Title: | PancFit: Do Angiogenic Biomarkers Correlate with Improved Progression Free Survival in Pancreatic Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1R21CA218732 |
| Date: | 2017 - 2018 |
| Title: | Effect of preoperative exercise on physical function, quality of life and chemodelivery in patients with pancreatic cancer |
| Funding Source: | Mike Hogg Award, MD Anderson Cancer Center |
| Role: | CO-I |
| Date: | 2017 - 2020 |
| Title: | Prehab Exercise for Pancreatic Cancer Patients Undergoing Pre-surgical Chemotherapy |
| Funding Source: | Wyck Knox Jr. Family Foundation Philanthropic Funds |
| Role: | Co-PI |
| Date: | 2016 - 2019 |
| Title: | Energy Balance Strategies for Enhancing Therapy and Improving Survivorship for Pediatric Cancer |
| Funding Source: | Multidisciplinary Research Program, The University of Texas MD Anderson Cancer Center |
| Role: | Co-PI |
| Date: | 2016 - 2017 |
| Title: | 3Dimensional models of Ewing's sarcoma for evaluation of tumor-endothelial interactions |
| Funding Source: | Oncomatryx Research Development Award |
| Role: | Co-PI |
| Date: | 2014 - Present |
| Title: | Exercise induced shear stress enhances chemotherapy efficacy by vascular remodeling |
| Funding Source: | Transdisciplinary Research on Energetics and Cancer Consortium (TREC) |
| Role: | PI |
| Date: | 2014 - 2014 |
| Title: | Differential NFAT target regulation in endothelial cells |
| Funding Source: | Union for International Cancer Control |
| Role: | PI |
| Date: | 2011 - 2014 |
| Title: | Immunobiology of Normal and Neoplastic Lymphocytes Training Program, The calcineurin-NFAT pathway negatively regulates megakaryopoiesis |
| Funding Source: | NIH/NCI |
| Role: | Trainee |
| ID: | 5T32CA009140 |
| Date: | 2008 - 2010 |
| Title: | Center for Clinical and Translational Sciences T32 Training Grant Program, The Role of Delta like ligand 4 in vasculogenesis in Ewing's sarcoma |
| Funding Source: | NIH/NCI |
| Role: | Trainee |
| ID: | TL1RR024147 |
| Date: | 2005 - 2010 |
| Title: | Award given to incoming students in recognition of academic achievements |
| Funding Source: | The University of Texas MD Anderson Cancer Center at Houston Graduate School of Biomedical Sciences Faculty and Alumni Merit Fellowship |
| Role: | PI |
| Title: | Conference Grant: Translating Energy Balance from Bench to Communities: Application of Parallel Animal-Human Studies |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | R13CA254014 |
Selected Publications
Peer-Reviewed Articles
- Ngo-Huang AT, Parker NH, Xiao L, Schadler K, Petzel MQB, Prakash LR, Kim MP, Tzeng CD, Lee JE, Ikoma N, Wolff RA, Javle MM, Koay EJ, Pant SD, Folloder JP, Wang X, Cotto AM, Ju YR, Garg N, Wang H, Bruera ED, Basen-Engquist KM, Katz MHG. Effects of a Pragmatic Home-based Exercise Program Concurrent With Neoadjuvant Therapy on Physical Function of Patients With Pancreatic Cancer: The PancFit Randomized Clinical Trial. Ann Surg(1):22-30, 2023. e-Pub 2023. PMID: 37026453.
- Miriam B Garcia, Schadler K, Chandra J, Clinton S, Courneya KS, Monserrate ZC, Daniel CR, Dannenberg AJ, WD Wahnefried, Dewhirst Mark, Fabian C, Hursting SD, Irwin ML, Iyengar N, McQuade JL, Schmitz KH, Engquist KB. Translating energy balance research from the bench to the clinic to the community: Parallel animal-human studies in cancer. CA Cancer J Clin, 2023. e-Pub 2023. PMID: 36825928.
- Savage H, Pareek S, Lee J, Ballarò R, Conterno Minussi D, Hayek K, Sadullozoda M, Lochmann BS, McQuade JL, LaVoy EC, Marmonti E, Patel H, Wang G, Imanishi M, Kotla S, Abe JI, Schadler K. Aerobic exercise alters the melanoma microenvironment and modulates ERK5 S496 phosphorylation. Cancer immunology research, 2023. e-Pub 2023. PMID: 37307577.
- Abe JI, Imanishi M, Li S, Zhang A, Ko KA, Samanthapudi VSK, Lee LL, Bojorges AP, Gi YJ, Hobbs BP, Deswal A, Herrmann J, Lin SH, Chini EN, Shen YH, Schadler K, Nguyen TH, Gupte AA, Reyes-Gibby C, Yeung SJ, Abe RJ, Olmsted-Davis EA, Krishnan S, Dantzer R, Palaskas NL, Cooke JP, Pownall HJ, Yoshimoto M, Fujiwara K, Hamilton DJ, Burks JK, Wang G, Le NT, Kotla S. An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis. Circulation research, 2023. e-Pub 2023. PMID: 37264926.
- Imanishi M, Cheng H, Kotla S, Deswal A, N-T L, Chini E, Ko KA, Samanthapudi VSK, L-L L, Herrmann J, Xu X, Reyes-Gibby C, S-CJ Y, Schadler K, Yusuf SW, Liao Z, Nurieva R, E-aD A, Burks JK, Palaskas NL, Cooke JP, Lin SH, Kobayashi M, Abe J-i YMA. Radiation therapy induces immunosenescence mediated by p90RSK. Frontiers, 2022. e-Pub 2022. PMID: 36426217.
- Lee J, Savage H, Maegawa S, Ballarò R, Pareek S, Guerrouahen BS, Gopalakrishnan V, Schadler K. Exercise Promotes Pro-Apoptotic Ceramide Signaling in a Mouse Melanoma Model. Cancers, 2022. e-Pub 2022. PMID: 36077841.
- Kurz E, Hirsch CA, Dalton T, Shadaloey SA, Khodadadi-Jamayran A, Miller G, Pareek S, Rajaei H, Mohindroo C, Baydogan S, Ngo-Huang A, Parker N, Katz MHG, Petzel M, Vucic E, McAllister F, Schadler K, Winograd R, Bar-Sagi D. Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer. Cancer Cell 40(7):720-737.e5, 2022. e-Pub 2022. PMID: 35660135.
- Huang SB, Rivas P, Yang X, Lai Z, Chen Y, Schadler K, Hu M, Reddick RL, Ghosh R, Kumar AP. SIRT1 inhibition-induced senescence as a strategy to prevent prostate cancer progression. Mol Carcinog 61(7):702-716, 2022. e-Pub 2022. PMID: 35452563.
- Gupta P, Hodgman CF, Alvarez-Florez C, Schadler K, Markofski MM, O'Connor DP, LaVoy EC. Comparison of three exercise interventions with and without gemcitabine treatment on pancreatic tumor growth in mice: No impact on tumor infiltrating lymphocytes. Front Physiol 13:1039988, 2022. e-Pub 2022. PMID: 36479351.
- Shapiro DD, Soeung M, Perelli L, Dondossola E, Surasi DS, Tripathi DN, Bertocchio JP, Carbone F, Starbuck MW, Van Alstine ML, Rao P, Katz MHG, Parker NH, Shah AY, Carugo A, Heffernan TP, Schadler K, Logothetis C, Walker CL, Wood CG, Karam JA, Draetta GF, Tannir NM, Genovese G, Msaouel P. Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies. Cancers (Basel) 13(23), 2021. e-Pub 2021. PMID: 34885132.
- Kotla S, Zhang A, Imanishi M, Ko KA, Lin SH, Gi YJ, Moczygemba M, Isgandarova S, Schadler K, Chung C, Milgrom SA, Banchs J, Yusuf SW, Amaya DN, h G, Thomas TN, Shen YH, Deswal A, Herrmann J, Kleinerman ES, Entman ML, Cooke JP, Schifitto G, Maggirwar SB, McBeath E, Gupte AA, Ss K, Patel ZS, Yoon Y, Burks JK, Fujiwara K, Brookes PS, Le NT, Hamilton DJ, Abe JI. Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation. Redox Biology, 2021. e-Pub 2021. PMID: 34619528.
- Shaik S, Maegawa S, Haltom AR, Wang F, Xiao X, Dobson T, Sharma A, Yang Y, Swaminathan J, Kundra V, Li XN, Schadler K, Harmanci A, Xu L, Gopalakrishnan V. REST promotes ETS1-dependent vascular growth in medulloblastoma. Mol Oncol 15(5):1486-1506, 2021. e-Pub 2021. PMID: 33469989.
- Parker NH, Gorzelitz J, Ngo-Huang A, Caan BJ, Prakash L, Garg N, Petzel MQB, Schadler K, Basen-Engquist K, Katz M. The Role of Home-Based Exercise in Maintaining Skeletal Muscle During Preoperative Pancreatic Cancer Treatment. Integrative Cancer Therapies 20, 2021. e-Pub 2021. PMID: 33870744.
- Shaik S, Maegawa S, Haltom AR, Wang F, Xiao X, Dobson T, Sharma A, Yang Y, Swaminathan J, Kundra V, Li XN, Schadler K, Harmanci A, Xu L, Gopalakrishnan V. REST promotes ETS1‐dependent vascular growth in medulloblastoma. Molecular Oncology, 2021. e-Pub 2021. PMID: 33469989.
- Banerjee P, Kotla S, Reddy VL, Abe RJ, Davis EA, Cooke JP, Schadler K, Deswal A, Herrmann J, Lin SH, Abe JI, Le NT. Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer. Frontiers in Cardiovascular Medicine, 2021. e-Pub 2021. PMID: 34746270.
- Abe RJ, Savage H, Imanishi M, Banerjee P, Kotla S, Paez-Mayorga J, Taunton J, Fujiwara K, Won JH, Yusuf SW, Palaskas NL, Banchs J, Lin SH, Schadler K, Abe J, Le N. p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway. Frontiers Cardiovascular Medicine, 2020. e-Pub 2020. PMID: 33304925.
- Swartz MC, Teague AK, Wells SJ, Honey T, Fu M, Mahadeo KM, Kabiri LS, Chandra J, Moody K, Schadler K. Feasibility and Acceptability Findings of an Energy Balance Data Repository of Children, Adolescents, and Young Adults with Cancer. Journal of Clinical Medicine 9(9), 2020. e-Pub 2020. PMID: 32899945.
- Parr SK, Liang J, Schadler K, Gilchrist SC, Steele CC, Ade CJ. Anticancer Therapy–Related Increases in Arterial Stiffness: A Systematic Review and Meta‐Analysis. Journal of the American Heart Association, 2020. e-Pub 2020. PMID: 32648507.
- Marmonti E, Savage H, Zhang A, Alvarez C, Morrell MG, Harden A, Buzbee M, Schadler K. Modulating Sphingosine-1-Phosphate receptors to improve chemotherapy efficacy against Ewing sarcoma. International Journal of Cancer, 2020. e-Pub 2020. PMID: 31922252.
- a N, Parker NH, Bruera E, Lee RE, Simpson R, O'Connor DP, Petzel MQ, Fontillas RC, Schadler K, Xiao L, Wang X, Fogelman D, Sahai SK, Lee JE, Basen-Engquist K, Katz MH. Home-Based Exercise Prehabilitation During Preoperative Treatment for Pancreatic Cancer Is Associated With Improvement in Physical Function and Quality of Life. Integrative Cancer Therapies, 2019. e-Pub 2019. PMID: 31858837.
- Parker NH, Lee RE, O'Connor DP, Ngo-Huang A, Petzel MQB, Schadler K, Wang X, Xiao L, Fogelman D, Simpson R, Fleming JB, Lee JE, Tzeng CD, Sahai SK, Basen-Engquist K, Katz MHG. Supports and Barriers to Home-Based Physical Activity During Preoperative Treatment of Pancreatic Cancer: A Mixed-Methods Study. Journal of Physical Activity & Health, 2019. e-Pub 2019. PMID: 31592772.
- Florez Bedoya CA, Ferreira Cardosa AC, Parker N, Ngo-Huang A, Petzel MQ, Kim MP, Fogelman D, Romero SG, Wang H, Park M, Katz MH, Schadler K. Exercise during preoperative therapy increases tumor vascularity in pancreatic tumor patients. Scientific Reports, 2019. e-Pub 2019. PMID: 31562341.
- Joffe L, Schadler K, Shen W, Ladas EJ. Body Composition in Pediatric Solid Tumors: State of the Science and Future Directions. JNCI Monographs 2019(54):144-148, 2019. e-Pub 2019. PMID: 31532526.
- Morrell MBG, Alvarez-Florez C, Zhang A, Kleinerman ES, Savage H, Marmonti E, Park M, Shaw A, Schadler K. Vascular modulation through exercise improves chemotherapy efficacy in Ewing sarcoma. Pediatric Blood Cancer, 2019. e-Pub 2019. PMID: 31136074.
- Puerto-Camacho P, Amaral AT, Lamhamedi-Cherradi SE, Menegaz BA, Castillo-Ecija H, Ordonez JL, Dominguez S, Jordan-Perez C, Diaz-Martin J, Romero-Perez L, Lopez-Alvarez M, Civantos-Jubera G, Robles-Frias MJ, Biscuola M, Ferrer C, Mora J, Cuglievan B, Schadler K, Seifert O, Kontermann R, Pfizenmaier K, Simon L, Fabre M, Carcaboso AM, Ludwig JA, de Alava E. Preclinical Efficacy of Endoglin - Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma. Clin Cancer Res, 2019. e-Pub 2019. PMID: 30420447.
- Bhang DH, Kim BJ, Kim BG, Schadler K, Baek KH, Kim YH, Hsiao W, Ding BS, Rafii S, Weiss MJ, Chou ST, Kolon TF, Ginsberg JP, Ryu BY, Ryeom S. Testicular endothelial cells are a critical population in the germline stem cell niche. Nature Communications, 2018. e-Pub 2018. PMID: 30348976.
- Parker NH, Ngo-Huang A, Lee RE, O'Connor DP, Basen-Engquist KM, Petzel MQB, Wang X, Xiao L, Fogelman DR, Schadler K, Simpson RJ, Fleming JB, Lee JE, Varadhachary GR, Sahai SK, Katz MHG. Physical activity and exercise during preoperative pancreatic cancer treatment. Support Care Cancer, 2018. e-Pub 2018. PMID: 30334105.
- Wang F, Iskra B, Kleinerman E, Alvarez-Florez C, Andrews T, Shaw A, Chandra J, Schadler K, Aune GJ. Aerobic Exercise During Early Murine Doxorubicin Exposure Mitigates Cardiac Toxicity. Journal of Pediatric Hematology/Oncology 40(3):208-215, 2018. e-Pub 2018. PMID: 29557918.
- Shaik S, Kennis B, Maegawa S, Schadler K, Yang Y, Callegari K, Lulla RR, Goldman S, Nazarian J, Rajaram V, Fangusaro J, Gopalakrishnan V. REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature. Oncotarget 9(4):5233-5250, 2018. e-Pub 2018. PMID: 29435175.
- Ngo-Huang A, Parker NH, Wang X, Petzel MQB, Fogelman D, Schadler K, Bruera E, Fleming JB, Lee JE, Katz MHG. Home-based exercise during preoperative therapy for pancreatic cancer. Langenbecks Arch Surg. e-Pub 2017. PMID: 28710540.
- McManus M, Kleinerman E, Yang Y, Livingston JA, Mortus J, Rivera R, Zweidler-McKay P, Schadler K. Hes4: A potential prognostic biomarker for newly diagnosed patients with high-grade osteosarcoma. Pediatr Blood Cancer 64(5), 2017. e-Pub 2017. PMID: 27786411.
- Moonat HR, Huang G, Dhupkar P, Schadler K, Gordon N, Kleinerman E. Combination of Interleukin-11Ra Chimeric Antigen Receptor T-cells and Programmed Death-1 Blockade as an Approach to Targeting Osteosarcoma Cells In vitro. Cancer Translational Medicine 3(4):139-45, 2017. e-Pub 2017.
- Schadler K, Thomas NJ, Galie PA, Bhang DH, Roby KC, Addai P, Till JE, Sturgeon K, Zaslavsky CS, Chen SR. Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy. Oncotarget, 2016. e-Pub 2016. PMID: 27589843.
- Suehiro J, Kanki Y, Makihara C, Schadler K, Miura M, Manabe Y, Aburatani H, Kodama T, Minami T. Genome-wide approaches reveal functional vascular endothelial growth factor (VEGF)-inducible nuclear factor of activated T cells (NFAT) c1 binding to angiogenesis-related genes in the endothelium. J Biol Chem 289(42):29044-59, 2014. e-Pub 2014. PMID: 25157100.
- Sturgeon K, Schadler K, Muthukumaran G, Ding D, Bajulaiye A, Thomas NJ, Ferrari V, Ryeom S, Libonati JR. Concomitant low-dose doxorubicin treatment and exercise. Am J Physiol Regul Integr Comp Physiol 307(6):R685-92, 2014. e-Pub 2014. PMID: 25009215.
- Schadler K, Crosby EJ, Zhou AY, Bhang DH, Braunstein L, Baek KH, Crawford D, Crawford A, Angelosanto J, Wherry EJ, Ryeom S. Immunosurveillance by antiangiogenesis: tumor growth arrest by T cell-derived thrombospondin-1. Cancer Res 74(8):2171-81, 2014. e-Pub 2014. PMID: 24590059.
- Minami T, Jiang S, Schadler K, Suehiro J, Osawa T, Oike Y, Miura M, Naito M, Kodama T, Ryeom S. The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases. Cell Rep 4(4):709-23, 2013. e-Pub 2013. PMID: 23954784.
- Zaslavsky A, Chou ST, Schadler K, Lieberman A, Pimkin M, Kim YJ, Baek KH, Aird WC, Weiss MJ, Ryeom S. The calcineurin-NFAT pathway negatively regulates megakaryopoiesis. Blood 121(16):3205-15, 2013. e-Pub 2013. PMID: 23446734.
- Stewart K, Zhou Z, Zweidler-McKay P, Kleinerman ES. Delta-like ligand 4-Notch signaling regulates bone marrow-derived pericyte/vascular smooth muscle cell formation. Blood 117(2):719-726, 2013. e-Pub 2013. PMID: 20944072.
- Zhou Z, Stewart K, Yu L, Kleinerman ES. Bone marrow cells participate in tumor vessel formation that supports the growth of Ewing's sarcoma in the lung. Angiogenesis 14(2):125-33, 2011. e-Pub 2011. PMID: 21184173.
- Schadler K, Zweidler-McKay PA, Guan H, Kleinerman ES. Delta-like ligand 4 plays a critical role in pericyte/vascular smooth muscle cell formation during vasculogenesis and tumor vessel expansion in Ewing's sarcoma. Clin Cancer Res 16(3):848-56, 2010. e-Pub 2010. PMID: 20103680.
- Reddy K, Zhou Z, Schadler K, Jia SF, Kleinerman ES. Bone Marrow Subsets Differentiate into Endothelial Cells and Pericytes Contributing to Ewing's Tumor Vessels. Molecular Cancer Research 6(6):929-36, 2008. e-Pub 2008. PMID: 18567797.
Abstracts
- Casso-Chapa B, Vazquez González NA, Le NT, Palaskas NL, Nead KT, Eutsey LP, Samanthapudi VSK, Osborn AM, Lee J, Mejia G, Hoang O, Lin SH, Deswal A, Herrmann J, Wang G, Kirkland JL, Krishnan S, Wehrens XHT, Chini EN, Yusuf SW, Iliescu CA, Jain A, Burks JK, SCHADLER K, Seeley E, Lorenzi PL, Chau KM, Ostos-Mendoza KC, Grumbach IM, Brookes PS, Hanssen NMJ, de Winther MPJ, Yvan-Charvet L, Kotla S, Abe JI. Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease. Arterioscler Thromb Vasc Biol. 2025(Mar;45(3)):372-385, 2025. e-Pub 2025. PMID: 39817327.
- . Factors Associated with In-patient and Outpatient Rehabilitation Services among Childhood Cancer Survivors. The Archives of Physical Medicine and Rehabilitation 105(4):e25, 2024. e-Pub 2024.
- Ballarò R, Pareek S, Lee J, Patel H, Schadler K. Aerobic exercise impacts the tumor microenvironment by altering CAF abundance and composition in pancreatic cancer. ACSM, 2023. e-Pub 2023.
- Kotla S, Abe J, Imanish M, Li S, Zhang A, Ko KA, Samanthapudi V, Lee L, Deswal A, Lin SH, Schadler K, Fujiwara K, Hamilton D, Jared B, Wang G, Le N, Palaska N. An ERK5-NRF2 axis mediates senescence-associated stemness and atherosclerosis. 29th Annual Conference of the Society for Redox Biology and Medicine, 2022. e-Pub 2022.
- Baumfalk DR, Hammond ST, Parr SK, Horn AG, Kunkel ON, Schadler K, Ade CJ, Behnke BJ. Effects of Exercise on Aortic Stiffness Associated with 5-Flurouracil in Rats. Experimental Biology 36(S1), 2022. e-Pub 2022.
- Schadler K, Hammond S. Acute exercise in 5-Fluorouracil cardiotoxicity: Effects on cardiac function and reverse phase protein analysis. American Physiological Society, 2022. e-Pub 2022.
- Schadler K, Baumfalk D. Effects of Exercise on Aortic Stiffness Associated with 5-Flurouracil in Rats. American Physiological Society, 2022. e-Pub 2022.
- Schadler K, Lee J. Exercise Alters Ceramide Metabolism in Melanoma. American Physiological Society, 2022. e-Pub 2022.
- Ngo-Huang A, Parker NH, Xiao L, Schadler K, Petzel MB, Prakash L, Kim MP, Tzeng CW, Lee JE, Ikoma N, Wolff RA, Javle M, Koay E, Pant S, Folloder J, Cotta A, Ju YR, Garg N, Bruera E, Basen-Engquist K, Katz MHG. Effects of Exercise on Physical Function During Neoadjuvant Therapy for Pancreatic Cancer: A Randomized Controlled Trial. American Surgical Association, 2022. e-Pub 2022.
- Hammond ST, Baumfalk DR, Horn AG, Kunlel ON, Parr1 SK, Colburn TD, Schadler K, Ade CJ, J Behnke &B. Acute exercise in 5-Fluorouracil cardiotoxicity: Effects on cardiac function and reverse phase protein analysis. Experimental Biology, 2022. e-Pub 2022.
- Ballarò R, Pareek S, Lee J, Savage H, Schadler K, Guerrouahen B. Differential impact of varied exercise intensities on vasculature of pancreatic cancer in mice. NAVBO, 2022. e-Pub 2022.
- Swartz MC, Kelly D, Schadler K, Andersen C, Wells SJ, Zhang S, Rajan A, Heaton A, Moody K. System-level barriers and facilitators to cancer rehabilitation delivery for children with cancer. ASCO, 2022. e-Pub 2022.
- Savage H, Pareek S, Lee J, Ballaro R, Hayek K, Samanthapudi V, Ko KA, Imanishi M, Kotla S, Abe J, Schadler K. Aerobic exercise suppresses melanoma tumor growth via upregulating ERK5 S496 phosphorylation. AACR, 2022. e-Pub 2022.
- Lee J, Savage H, Maegawa S, Ballardo R, Pareek S, Guerrouahen B, Gopalakrishnan V, Schadler K. Exercise alters ceramide metabolism in melanoma. Experimental Biology, 2022. e-Pub 2022.
- Kotla S, Imanishi M, Zhang A, Ko KA, Samanthapudi VK, Savage H, Schadler K, Abe RJ, Gupte AA, Deswal A, Lin SH, Reyes-Gibby6 C, Yeung SJ, Pownall HJ, Fujiwara K, Hamilton DJ, Li S, Wang G, Le N, Abe AJ. ERK5 S496 phosphorylation, but not ERK5 kinase or transcriptional activity, is responsible for promoting macrophage inflammation and mitochondrial dysfunction via upregulating novel site of NRF2 K518 SUMOylation. IMC, 2022. e-Pub 2022.
- Pareek S, Ballaro R, Savage H, Lee J, Patel H, LaVoy E, McAllister F, Schadler K. Aerobic exercise reduces immunosuppression in the pancreatic adenocarcinoma microenvironment in an intensity-dependent manner, 2022. e-Pub 2022.
- Schadler K. The endothelium as a target of transplant related injury. American Society of Pediatric Hematology and Oncology Annual Conference, 2021. e-Pub 2021.
- LaVoy EC, Gupta P, Hodgman C, Schadler K. Tumor growth reduced and tumor-infiltrating lymphocytes increased with exercise training in mouse model of pancreatic cancer. Integrative Physiology of Medicine, 2020. e-Pub 2020.
- Ballaro R, Marmonti E, Savage H, Garcia M, Bedoya C, Abe J, Schadler K. Exercise Improves Tumor Vasculature Function via S1P Receptor Signaling, 2020. e-Pub 2020.
- Lee J, Santiago Enriquez J, Pudakalakatti S, Chen W, Tran A, Pareek S, Savage H, Lam T, Cohen E, Cho S, Seeley E, Burk J, Abe J, Wang G, Bhattacharya P, Schadler K. Exercise-induced Metabolic Stress Drives Apoptotic Adaptation In Melanoma Tumors 57(Medicine & Science in Sports & Exercise® (MSSE)).
- SCHADLER K. The Science Behind Prehab Exercise. Cancer Rehabilitation Symposium 2025: Advancing Patient Centered Care Across the Cancer Continuum.
- Tirumala P, Lee J, Schadler K. Understanding the role of exercise in lymphatic vessel regulation in melanoma. American Association of Cancer Research Annual Meeting.
- Tirumala P, Lee J, Schadler K. Understanding the role of exercise in lymphatic vessel regulation in melanoma. American College of Sports Medicine (ACSM) Annual Meeting.
- Pareek S, Ballaro R, Lee J, Patel H, SCHADLER K. Exercise capacity regulates anti-tumor immunity in pancreatic cancer. PsychoNeuroImmunology Research Society 2024 Annual Meeting.
- SCHADLER K. Tele-PanCFit: Video-Supervised Exercise Prehabilitation for Patients with Respectable Pancreatic Cancer (clinical trial in-progress). MASCC/AFSOS/ISOO 2024 Annual Meeting.
- Lee J, Ko K, Osborn A, Mendoza K, Reyes K, Mejia G, Samanthapudi V, Hoang O, Deswal A, Schadler K, Tu-Le N, Kolta S, Abe J. Immunocheckpoint Inhibitor Specifically Accelerates Coronary Atherosclerosis Not Aorta. Division of Internal Medicine Retreat.
- Lee J, SCHADLER K. Immunocheckpoint Inhibitor Specifically Accelerates Coronary Atherosclerosis Not Aorta. 2024 Vascular Scientific Sessions.
Book Chapters
- Garcia MM, Ness KK, Schadler K. Exercise and Physical Activity in Patients with Osteosarcoma and Survivors. In: Current Advances in the Science of Osteosarcoma. Springer International Publishing, 2020.
- Savage H, Schadler KL. Mechanisms of Exercise in Cancer Prevention, Treatment, and Survivorship. In: Exercise Oncology - Prescribing Physical Activity Before and After a Cancer Diagnosis. Springer Nature Switzerland AG, 61-83, 2020.
Patient Reviews
CV information above last modified February 25, 2026