Kerollos Wanis, MD, PhD

Peer-Reviewed Articles

1. Wanis, K, Krasniqi, R, Sun, SX, Resetkova, E, Hwang, RF, Hunt, KK, Candelaria, RP, Huo, L, Singh, P. Sentinel Lymph Node Positivity and Utility of Frozen Section Diagnosis following Neoadjuvant Therapy in Patients with Clinically Node-Negative, Hormone Receptor-Positive, HER2-Negative Breast Cancer. Annals of surgical oncology 33(8):7237-7243, 2026. e-Pub 2026. PMID: 42135547.
2. Madenci, AL, Wanis, K, Trinquart, L, Kurgansky, KE, Gerlovin, H, Hernán, MA. A Call for Randomization. Epidemiology (Cambridge, Mass.) 37(4):476-478, 2026. e-Pub 2026. PMID: 41570240.
3. Chen, J, Wanis, K, Rahman, M, Gianchandani, A, Bedrosian, I, Tamirisa, N, Yi, M, Singareeka Raghavendra, A, Singh, P, Teshome, M, Sun, SX, Kuerer, HM, Hunt, KK, Meric-Bernstam, F, Adesoye, T. Implications for Sentinel Lymph Node Biopsy Omission in Patients with Early-Stage Node-Negative HR+/HER2− Breast Cancer Undergoing Mastectomy. Annals of surgical oncology 33(7):6414-6421, 2026. e-Pub 2026. PMID: 41949735.
4. Delgado Casanova, LB, Dhamne, S, Resetkova, E, Guirguis, MS, Puvvala, A, Bevers, TB, Bedrosian, I, Huo, L, Wanis, K. Risk of malignancy after diagnosis of radial sclerosing lesion without atypia. Breast Cancer Research and Treatment 217(2), 2026. e-Pub 2026. PMID: 42257745.
5. Dumas, E, Hamy, AS, Wanis, K, Jochum, F, Coussy, F, Giacchetti, S, Gaillard, T, Laas, E, Houzard, S, Le Bihan-Benjamin, C, Reyal, F, Gougis, P, Stensrud, MJ. Outcomes of Anastrozole, Letrozole, and Exemestane in Patients With Postmenopausal Breast Cancer. JAMA Network Open 8(12), 2025. e-Pub 2025. PMID: 41632158.
6. Wanis, K, Dong, W, Shen, Y, Meric-Bernstam, F, Adesoye, T, Kuerer, HM, Caudle, AS, Tamirisa, N, DeSnyder, SM, Sun, SX, Bedrosian, I, Singh, P, Cox, SE, Hunt, KK, Hwang, RF. Predicting pathologic ≥N2 disease in women with breast cancer. npj Breast Cancer 11(1), 2025. e-Pub 2025. PMID: 40404657.
7. Huynh, VD, Mouabbi, JA, Kuerer, HM, Wanis, K, Abdel-Salam, HM, Gutierrez, AM, Johnson, HM, Lucci, A, Hunt, KK, Arun, BK. Characterization of the Germline Pathogenic Mutational Landscape and Oncologic Outcomes Among 877 Patients with Invasive Lobular Carcinoma. Annals of surgical oncology 32(8):5477-5488, 2025. e-Pub 2025. PMID: 40314901.
8. Wanis, K, Mitchell, MP, Giordano, SH, Litton, J, Shaitelman, SF, Tamirisa, N, Bedrosian, I, Dong, W, Shen, Y, Hunt, KK, Singh, P, Sun, SX, Caudle, AS, Kuerer, HM, Meric-Bernstam, F, Hwang, RF, Adesoye, T. Implications of omitting sentinel lymph node biopsy on adjuvant decision making for patients with small breast cancers. Cancer 131(11), 2025. e-Pub 2025. PMID: 40433858.
9. Wanis, K, Stensrud, MJ, Sarvet, AL. Separable effects for adherence. American journal of epidemiology 194(4):1122-1130, 2025. e-Pub 2025. PMID: 39142687.
10. Messinger, CJ, Bateman, BT, Wanis, K. Emulating Target Trials to Study Perioperative and Critical Care Interventions with Observational Data. Anesthesiology 142(4):611-627, 2025. e-Pub 2025. PMID: 40067038.
11. Mellado-Artigas, R, Borrat, X, Ferreyro, BL, Yarnell, C, Hao, S, Wanis, K, Barbeta, E, Torres, A, Ferrando, C, Brochard, L. Effect of immediate initiation of invasive ventilation on mortality in acute hypoxemic respiratory failure. Critical Care 28(1), 2024. e-Pub 2024. PMID: 38730306.
12. Byrne, MM, Chávez-Villa, M, Ruffolo, LI, Wanis, K, Belt, B, Tomiyama, K, Hernandez-Alejandro, R. Progression-Free Survival for Liver Transplant vs Alternative Therapy in Unresectable Colorectal Liver Metastasis. JAMA Surgery 159(9):1089-1091, 2024. e-Pub 2024. PMID: 39046752.
13. Wanis, K, Sarvet, AL. Placebo Adherence as a Negative Control Exposure. Epidemiology 35(5):654-659, 2024. e-Pub 2024. PMID: 38967970.
14. Madenci, AL, Kurgansky, KE, Dickerman, BA, Gerlovin, H, Wanis, K, Smith, AD, Trinqart, L, Gagnon, D, Cho, K, Gaziano, JM, Casas, JP, Robins, JM, Hernán, MA. Estimating the Effect of Bariatric Surgery on Cardiovascular Events Using Observational Data?. Epidemiology 35(5):721-729, 2024. e-Pub 2024. PMID: 39024034.
15. Wanis, K, Sarvet, AL, Wen, L, Block, JP, Rifas-Shiman, SL, Robins, JM, Young, JG. Grace periods in comparative effectiveness studies of sustained treatments. Journal of the Royal Statistical Society. Series A: Statistics in Society 187(3):796-810, 2024. e-Pub 2024. PMID: 39281783.
16. Madenci AL, Kurgansky KE, Dickerman BA, Gerlovin H, Wanis KN, Smith AD, Trinqart L, Gagnon DR, Cho D, Gaziano JM, Casas JP, Robins JM, Hernán MA. Estimating the effect of bariatric surgery on cardiovascular events using observational data?. Epidemiology 35(5):721-729, 2024. e-Pub 2024.
17. Wanis KN, Kuerer H, Sun S, Hunt K, Glencer A, Teshome M, Lucci A, Weiser R, Johnson H, Smith B, Guitierrez-Barrera A, Shaitelman S, Arun B. Clinical outcomes for BRCA pathogenic variant carriers with breast cancer undergoing breast conservation. JAMA Network Open 7(6):e2418486, 2024. e-Pub 2024.
18. Dzhemiliev A, Kizub D, Wanis KN, Allar BG, Vus V, Maliovana A, Huivaniuk I, Kopetskyi V, Beznosenko A, Shabat G, Antoniv M, Suprun U, Melnitchouk N. Self-reported Factors Affecting Colorectal Cancer Screening in Primary Care Physician Practices in Ukraine. JCO Global Oncology 10:e2400053, 2024. e-Pub 2024.
19. Wanis KN, Goetz L, So A, Glencer AC, Sun SX, Teshome M, Resetkova E, Hwang RF, Hunt KK, Candelaria RP, Huo L, Singh P. The prevalence of sentinel lymph node positivity and implications for the utility of frozen section diagnosis following neoadjuvant systemic therapy in patients with clinically node-negative HER2-positive or triple-negative breast cancer. Annals of Surgical Oncology 31(11):7339-7346, 2024. e-Pub 2024.
20. Glencer AC, Wanis KN, Lucci A, Sun SX, Adesoye T, DeSnyder SM, Layman R, Woodward W, Hunt KK, Teshome M. Self-Reported Management of Inflammatory Breast Cancer Among the American Society of Breast Surgeons Membership: Consensus and Opportunities. Annals of Surgical Oncology 31(11):7326-7334, 2024. e-Pub 2024.
21. Sarvet, AL, Wanis, K, Young, JG, Hernandez-Alejandro, R, Stensrud, MJ. Longitudinal incremental propensity score interventions for limited resource settings. Biometrics 79(4):3418-3430, 2023. e-Pub 2023. PMID: 36942974.
22. Wanis, K, Madenci, AL, Hao, S, Moukheiber, M, Moukheiber, L, Moukheiber, D, Moukheiber, S, Young, JG, Celi, LA. Emulating Target Trials Comparing Early and Delayed Intubation Strategies. Chest 164(4):885-891, 2023. e-Pub 2023. PMID: 37150505.
23. Messinger, CJ, Madenci, AL, Wanis, K. Addressing the longitudinal components of surgical treatments. European journal of epidemiology 38(10):1019-1023, 2023. e-Pub 2023. PMID: 37667140.
24. Szmulewicz, AG, Wanis, K, Perlis, R, Hernandez-Diaz, S, Ongur, D, Hernán, MA. Emulating a Target Trial of Dynamic Treatment Strategies for Major Depressive Disorder Using Data From the STAR∗D Randomized Trial. Biological Psychiatry 93(12):1127-1136, 2023. e-Pub 2023. PMID: 36639294.
25. Yang M, McClure A, Wanis KN, Vogt K, Van Koughnett JA, Ott M, Vinden C. From Formation to Closure - Aggregate Morbidity and Mortality Associated With Defunctioning Loop Ileostomies. Dis Colon Rectum 65(9):1135-1142, 2022. e-Pub 2022.
26. Hawel JDE, Patel R, Peters T, Wanis K, Naidu A, Xu R, Elnahas AI, Alkhamesi NA, Schlachta CM. Colonic displacement as a marker of endoscopic skill: development of a novel tool for endoscopy training. Surg Endosc 36(5):3169-3177, 2022. e-Pub 2022.
27. Welten VM, Wanis KN, Madenci AL, Fields AC, Lu PW, Malizia RA, Yoo J, Goldberg JE, Irani JL, Bleday R, Melnitchouk N. The Effect of Facility Volume on Survival Following Proctectomy for Rectal Cancer. J Gastrointest Surg 26(1):150-160, 2022. e-Pub 2022.
28. Madenci AL, Wanis KN, Cooper Z, Subramanian SV, Haneuse S, Hofman A, Hernán M. Comparison of Mortality Risk With Different Surgeon and Hospital Operative Volumes Among Individuals Undergoing Pancreatectomy by Emulating Target Trials in US Medicare Beneficiaries. JAMA Netw Open 5(3):e221766, 2022. e-Pub 2022.
29. Welten VM, Wanis KN, Semeniv S, Shabat G, Dabekaussen KF, Davids JS, Beznosenko A, Suprun U, Soeteman DI, Melnitchouk N. Colonoscopy Needs for Implementation of a Colorectal Cancer Screening Program in Ukraine. World J Surg 46(10):2476-2486, 2022. e-Pub 2022.
30. Madenci AL, Wanis KN, Cooper Z, Haneuse S, Subramanian SV, Hofman A, Hernán MA. Strengthening Health Services Research Using Target Trial Emulation: An Application to Volume-Outcomes Studies. Am J Epidemiol 190(11):2453-2460, 2021. e-Pub 2021.
31. Wanis KN, Sarvet A, Ruffolo LI, Levstik MA, Tomiyama K, Al‐Judaibi BM, Stensrud MJ, Hernandez‐Alejandro R. Estimating the effect of increasing utilization of living donor liver transplantation using observational data. Transplant Int 34(4):648-656, 2021. e-Pub 2021.
32. Sharma G, Madenci AL, Wanis KN, Comment LA, Lotto CE, Shah SK, Ozaki CK, Subramanian SV, Eldrup-Jorgensen J, Belkin M. Association and Interplay of Surgeon and Hospital Volume with Mortality Following Open Abdominal Aortic Aneurysm Repair in the Modern Era. Journal of Vascular Surgery 73(5):1593-1602, 2021. e-Pub 2021.
33. Wanis KN, Linecker M, Madenci AL, Müller PC, Nüssler N, Brusadin R, Robles-Campos R, Hahn O, Serenari M, Jovine E, Lehwald N, Knoefel WT, Reese T, Oldhafer K, de Santibañes M, Ardiles V, Lurje G, Capelli R, Enne M, Ratti F, Aldrighetti L, Zhurbin AS, Voskanyan S, Machado M, Kitano Y, Adam R, Chardarov N, Skipenko O, Ferri V, Vicente E, Tomiyama K, Hernandez-Alejandro R. Variation in complications and mortality following ALPPS at early-adopting centers. HPB 23(1):46-55, 2021. e-Pub 2021.
34. Wanis KN, Madenci AL, Hernán MA, Murray EJ. Adjusting for adherence in randomized trials when adherence is measured as a continuous variable: An application to the Lipid Research Clinics Coronary Primary Prevention Trial. Clin Trials 17(5):570-575, 2020. e-Pub 2020.
35. Sarvet AL, Wanis KN, Stensrud MJ, Hernán MA. A Graphical Description of Partial Exchangeability. Epidemiology 31(3):365-368, 2020. e-Pub 2020.
36. Sonderman KA, Wolf LL, Madenci AL, Kwon NK, Armstrong LB, Wanis KN, Taylor K, Uribe-Leitz T, Koehlmoos TP, Jr RR, Weil BR, Weldon CB, Haider AH, Rice-Townsend SE. Opioid prescription patterns for children following laparoscopic appendectomy. Ann Surg 272(6):1149-1157, 2020. e-Pub 2020.
37. Maley JH, Wanis KN, Young JG, Celi LA. Mortality prediction models, causal effects, and end-of-life decision making in the intensive care unit. BMJ Health Care Inform 27(3):e100220, 2020. e-Pub 2020.
38. Szmulewicz A, Wanis KN, Gripper A, Angriman F, Hawel J, Elnahas A, Alkhamesi NA, Schlachta CM. Mental health quality of life after bariatric surgery: A systematic review and meta-analysis of randomized clinical trials. Clin Obes 9(1):e12290, 2019. e-Pub 2019.
39. Wanis KN, Maleyeff L, Van Koughnett JAM, Colquhoun PHD, Ott M, Leslie K, Hernandez-Alejandro R, Kim JJ. Health and Economic Impact of Intensive Surveillance for Distant Recurrence After Curative Treatment of Colon Cancer: A Mathematical Modeling Study. Dis Colon Rectum 62(7):872-881, 2019. e-Pub 2019.
40. Wanis KN, Madenci AL, Dokus MK, Orloff MS, Levstik MA, Hernandez-Alejandro R, Hernán MA. The meaning of confounding adjustment in the presence of multiple versions of treatment: an application to organ transplantation. Eur J Epidemiol 34(3):225-233, 2019. e-Pub 2019.
41. Smith S, White J, Wanis KN, Beckett A, McAlister VC, Hilsden R. The effectiveness of junctional tourniquets: a systematic review and meta-analysis. J Trauma Acute Care Surg 86(3):532-539, 2019. e-Pub 2019.
42. Tun-Abraham ME, Wanis K, Garcia-Ochoa C, Sela N, Sharma H, Al Hasan I, Quan D, Al-Judaibi B, Levstik M, Hernandez-Alejandro R. Can we reduce ischemic cholangiopathy rates in donation after cardiac death liver transplantation after 10 years of practice? Canadian single-centre experience. Can J Surg 62(1):44-51, 2019. e-Pub 2019.
43. Wanis KN, Madenci AL, Dokus MK, Tomiyama K, Al-Judaibi BM, Hernán MA, Hernandez-Alejandro R. The effect of the opioid epidemic on donation after cardiac death transplantation outcomes. Transplantation 103(5):973-979, 2019. e-Pub 2019.
44. Zener R, Istl AC, Wanis KN, Hocking D, Kachura J, Alshehri S, Mujoomdar A, Latosinsky S, Wireman D. Thirty-day complication rate of percutaneous gastrojejunostomy and gastrostomy tube insertion using a single-puncture, dual-anchor technique. Clin Imaging 50:104-108, 2018. e-Pub 2018.
45. Wanis KN, Ott M, Van Koughnett JAM, Colquhoun P, Brackstone M. Long-term oncological outcomes following emergency resection of colon cancer. Int J Colorectal Dis 33(11):1525-1532, 2018. e-Pub 2018.
46. Wanis KN, Ardiles V, Alvarez FA, Tun-Abraham ME, Linehan D, de Santibanes E, Hernandez-Alejandro R. Intermediate-term Survival and Quality of Life Outcomes in Patients with Advanced Colorectal Liver Metastases Undergoing ALPPS. Surgery 163(4):691-697, 2018. e-Pub 2018.
47. Murphy PB, Wanis K, Schlachta CM, Alkhamesi NA. Systematic review on recent advances in the surgical management of rectal prolapse. Minerva Chir 72(1):71-80, 2017. e-Pub 2017.
48. Al-Hasan I, Tun-Abraham ME, Wanis KN, Garcia-Ochoa C, Aljudaibi B, Levstik M, Hernandez-Alejandro R. Optimizing associated liver partition and portal vein ligation for staged hepatectomy outcomes: Surgical experience or appropriate patient selection?. Can J Surg 60(6):408-415, 2017. e-Pub 2017.
49. Wanis KN, Patel SVB, Brackstone M. Do moderate surgical treatment delays influence survival in colon cancer?. Dis Colon Rectum 60(12):1241-1249, 2017. e-Pub 2017.
50. Coffey JC, Wanis KN, Monbaliu D, Gilbo N, Selzner M, Vachharajani N, Levstik MA, Marquez M, Doyle MM, Pirenne J, Grant D, Heimbach JK, Chapman W, Vogt K, Hernandez-Alejandro R. The Influence of functional warm ischemia time on DCD Liver Transplant Recipients’ Outcomes. Clin Transplant 31(10), 2017. e-Pub 2017.
51. Wanis KN, Pineda K, Tun-Abraham M, Yeoman J, Welch S, Vogt K, Van Koughnett JA, Ott M, Hernandez-Alejandro R. Management of colorectal cancer with synchronous liver metastases: impact of multidisciplinary case conference review. Hepatobiliary Surg Nutr 6(3):162-169, 2017. e-Pub 2017.
52. Wanis KN, Emmerton-Coughlin HM, Coughlin S, Foley N, Vinden C. Systemic metronidazole may not reduce post-hemorrhoidectomy pain: a meta-analysis of randomized controlled trials. Dis Colon Rectum 60(4):446-455, 2017. e-Pub 2017.
53. Hasselgren K, Malago M, Vyas S, Robles-Campos R, Brusadin R, Linecker M, Petrowsky H, Clavien PA, Machado MA, Hernandez-Alejandro R, Wanis KN, Sandstrom P, Bjornsson B. Neoadjuvant chemotherapy does not affect Future Liver Remnant (FLR) growth and outcomes of ALPPS. Surgery 161(5):1255-1265, 2017. e-Pub 2017.
54. Wanis KN, Buac S, Linecker M, Ardiles V, Tun-Abraham ME, Robles-Campos R, Malago M, de Santibanes E, Clavien PA, Hernandez-Alejandro R. Patient survival after simultaneous ALPPS and colorectal resection. World J Surg 41(4):1119-1125, 2017. e-Pub 2017.
55. Wanis KN, Kanthan R. Diagnostic and prognostic features in adrenocortical carcinoma: a single institution case series and review of the literature. World J Surg Oncol 13:117, 2015. e-Pub 2015.
56. Wanis KN, Hunter AM, Harington MB, Groot G. Impact of an acute care surgery service on timeliness of care and surgeon satisfaction at a Canadian academic hospital: a retrospective study. World J Emerg Surg 9(1):4, 2014. e-Pub 2014.
57. Wanis K, Haimanot S, Kanthan R. Endoscopic Retrograde Cholangiopancreatography: A Review of Technique and Clinical Indications. J Gastroint Dig Syst 4:280, 2014. e-Pub 2014.
58. Wanis K, Oucharek J, Groot G. Quality of thyroid referrals in Saskatchewan. Qual Prim Care 21(4):247-52, 2013. e-Pub 2013.

Review Articles

1. Rangel M, Singh P, Tamirisa N, Albarracin CT, Bevers TB, Sarvet AL, Bedrosian I, Wanis KN. Active monitoring versus surgical excision for atypical ductal hyperplasia. Cancer Prev Res. e-Pub 2026.
2. Lattimore CM, Johnson HM, Kuerer HM, Caudle AS, Giordano SH, Singh P, Hunt KK, Huo L, Wanis KN. Clipped Node Pathology as a Guide for Limited Axillary Surgery in Occult Breast Cancer. Ann. Surg. e-Pub 2026.
3. Fasano GA, Mouabbi J, Johnson HM, Lin HY, Wanis KN, Sun SX, Lucci A, Valero V, Mitchell M, Shen Y, Hunt KK, Kuerer H. Clinical Impact and Outcomes of Neoadjuvant Systemic Therapy for Invasive Lobular Carcinoma. Ann. Surg. Oncol. e-Pub 2026.
4. Lattimore CM, Wanis KN, Kuerer HM, Hunt KK, Giordano SH, Mithcell MP, Shaitelman SF, Tamirisa N, Shen Y, Dong W, Johnson HM. Is Mastectomy Necessary in Patients with Occult Breast Cancer and Advanced (N2/N3) Nodal Disease?. Ann. Surg. Oncol. e-Pub 2026.
5. Lai JH, Avancena ALV, Cata JP, Barner JC, Giordano SH, Park C, Zhao H, Evoy KE, Lin JK, Spencer JC, Chavez-MacGregor M, Hunt KK, Wanis KN. Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid-Related Adverse Events Following Surgery for Breast Cancer. Clin. Pharmacol. Ther. e-Pub 2026.

Book Chapters

1. Wanis KN, Nghiem BT, Hernandez-Alejandro R. ALPPS for CRLM – short- and long-term results. In: Colorectal Cancer Liver Metastases: A Comprehensive Guide to Management. Springer, 469-486, 2020.
2. Wanis KN, Hernandez-Alejandro R. Two-staged Approach to Liver Resection. In: Primary and Metastatic Liver Tumors. Springer, 373-386, 2018.
3. Hernandez-Alejandro R, Wanis KN. A Patient with Colorectal Cancer and Synchronous Liver Metastases: Simultaneous Resection of Primary and Metastases. In: Hepato-Pancreato-Biliary and Transplant Surgery: Practical Management of Dilemmas. Beaux Books, 121-127, 2018.