About Dr. Sokolov
Dr. Sokolov received his Diploma Degree in Physics in 1987 from the Moscow Engineering-Physics Institute, Russia, and Ph.D. in Biophysics in 1992 from Moscow State University, Russia. His Ph.D. thesis focused on biomedical applications of surface-enhanced Raman spectroscopy (SERS). Subsequently, he carried out research in the field of optical spectroscopy of biomolecules and bioanalytical chemistry as a postdoctoral fellow and a staff scientist at the Institute of Bioorganic Chemistry Russian Academy of Science, Moscow, Russia; the University of Reims, Reims, France; and the Department of Chemistry, Iowa State University, Ames, Iowa, U.S.A. Before joining the MD Anderson Cancer Center as a faculty member in 2002, Dr. Sokolov was a Research Scientist in Biomedical Engineering Program, the University of Texas at Austin.
Currently, Dr. Sokolov is a Professor of Imaging Physics and the director of the Biomedical Optics and NanoDiagnostics (BOND) laboratory, which develops nanotechnology-based platforms and optical imaging/spectroscopy devices for early detection, diagnosis/prognosis, and treatment of cancer and cardiovascular diseases. Achieving these objectives requires synergy between fundamental, exploratory, and translational research. Therefore, Dr. Sokolov’s approach to solving challenging biomedical problems is through fundamental studies leading to future clinical applications.
Dr. Sokolov has made seminal contributions to new directions of research in the field of bio-nanotechnology especially in the areas of ultra-sensitive biomolecular assays and molecular imaging that utilize unique physicochemical properties of plasmonic nanoparticles. Research and advanced-degree training in Dr. Sokolov’s lab has been funded by major grants from NCI, NIBIB, NHLBI, NSF, and the Whitaker Foundation.
Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Adjunct Associate Professor, Rice University, Houston, TX
Adjunct Associate Professor, The University of Texas at Austin, Austin, TX
Smart biophotonic probes for molecular imaging; m ethodology and devices for in vivo imaging and spectroscopy with optical contrast
Molecular and functional optical/photoacoustic imaging in vivo
Diag nostic assays for efficient capture, detection and analysis of rare cells in the body
|1992||Moscow State University, Moscow, Russia, PHD, Biophysics|
|1987||Moscow Engineering Physics Institute, Moscow, Russia, Diploma Degree, Physics|
|1993-1993||Postgraduate Training, Laboratory of Biomolecular Spectroscopy, Reims University, Reims|
|2015||Chair, V International Symposium on Topical Problems of Biophotonics, Nizhny Novgorod, Russia|
|2015||Elected Fellow, Optical Society of America|
|2013||General Chair, OSA Topical Meeting: Optical Molecular Probes, Imaging, and Drug Delivery|
|2012||Plenary Speaker, XVI International School on Optics, Laser Physics and Biophotonics, Saratov, Russia|
|2011||Chair, OSA Topical Meeting: Optical Molecular Probes, Imaging, and Drug Delivery|
|2011||Chair, III International Symposium on Topical Problems of Biophotonics|
|2008||Speaker, Lester Wolfe Workshop in Laser Biomedicine, MIT and Harvard-MIT Division of Health Science and Technology|
|2008||Chair, The Molecular Probes and Nanobio-optics Technical Group of the Optical Society of America (OSA)|
|2000||Whitaker Foundation Award|
|1993||Outstanding Young Scientist Award, Russian Academy of Sciences|
|1992||Fellowship, Centre National de la Recherché Scientifique (CNRS) France|
|1989||Young Scientist Award, Shemyakin Institute of Bioorganic Chemistry USSR Academy of Sciences|
- Lee KS, Andraud C, Tamada K, Sokolov K, Kotz KT, Zheng G. Feature issue introduction: biophotonic materials and applications. Biomed Opt Express 7(5):2078-81, 2016. e-Pub 2016. PMID: 27231644.
- Mallidi S, Kim S, Karpiouk A, Joshi PP, Sokolov K, Emelianov S. Visualization of molecular composition and functionality of cancer cells using nanoparticle-augmented ultrasound-guided photoacoustics. Photoacoustics 3(1):26-34, 2015. e-Pub 2015. PMID: 25893171.
- Huang YY, Chen P, Wu CH, Hoshino K, Sokolov K, Lane N, Liu H, Huebschman M, Frenkel E, Zhang JX. Screening and Molecular Analysis of Single Circulating Tumor Cells Using Micromagnet Array. Sci Rep 5:16047, 2015. e-Pub 2015. PMID: 26538094.
- Wu CH, Cook J, Emelianov S, and Sokolov K.. Multimodal Magneto-Plasmonic Nanoclusters for Biomedical Applications. Advanced Functional Materials, 2014. PMID: In process.
- Stover RJ, Murthy AK, Nie GD, Gourisankar S, Dear BJ, Truskett TM, Sokolov KV, Johnston KP. Quenched Assembly of NIR-Active Gold Nanoclusters Capped with Strongly Bound Ligands by Tuning Particle Charge via pH and Salinity. J Phys Chem C Nanomater Interfaces 118(26):14291-14298, 2014. e-Pub 2014. PMID: 25061496.
- Hoshino K, Joshi PP, Bhave G, Sokolov KV, Zhang X. Use of colloidal quantum dots as a digitally switched swept light source for gold nanoparticle based hyperspectral microscopy. Biomed Opt Express 5(5):1610-5, 2014. e-Pub 2014. PMID: 24877018.
- Wu CH, Sokolov K. Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters. J Vis Exp(90), 2014. e-Pub 2014. PMID: 25177973.
- Kuroda S, Tam J, Roth JA, Sokolov K, Ramesh R. EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage. Int J Nanomedicine 9:3825-39, 2014. e-Pub 2014. PMID: 25143731.
- Huang YY, Hoshino K, Chen P, Wu CH, Lane N, Huebschman M, Liu H, Sokolov K, Uhr JW, Frenkel EP, Zhang JXJ. Immunomagnetic nanoscreening of circulating tumor cells with a motion controlled microfluidic system. Biomed. Microdevices 15(4):673-681, 2013. PMID: 23109037.
- Jenkins JT, Halaney DL, Sokolov KV, Ma LL, Shipley HJ, Mahajan S, Louden CL, Asmis R, Milner TE, Johnston KP, Feldman MD. Excretion and toxicity of gold–iron nanoparticles. Nanomedicine 9(3):356-365, 2013. PMID: 22960192.
- Ma LL, Borwankar AU, Willsey BW, Yoon KY, Tam JO, Sokolov KV, Feldman MD, Milner TE, Johnston KP. Growth of textured thin Au coatings on iron oxide nanoparticles with near infrared absorbance. Nanotechnology 24:025606, 14 pages, 2013. PMID: 23238021.
- Murthy AK; Stover RJ; Borwankar AU; Nie GD; Gourisankar S; Truskett TM; Sokolov KV; Johnston KP. Equilibrium Gold Nanoclusters Quenched with Biodegradable Polymers,. ACS Nano 7(1):239-251, 2013. PMID: 23230905.
- Wu CH, Huang YY, Chen P, Hoshino K, Liu H, Frenkel EP, Zhang JXJ, Sokolov KV. Versatile Immunomagnetic Nanocarrier Platform for Capturing Cancer Cells. ACS Nano 7(10):8816-8823, 2013. PMID: 24016305.
- Joshi PP, Yoon SJ, Chen Y-S, Emelianov S, Sokolov KV. Development and optimization of near-IR contrast agents for immune cell tracking. Biomedical Optics Express 4(11):2609-2618, 2013.
- Luke GP, Myers JN, Emelianov SY, Sokolov KV. Sentinel lymph node biopsy revisited: ultrasound-guided photoacoustic detection of micrometastases using molecularly targeted plasmonic nanosensors. Cancer Res. e-Pub 2014. PMID: 25106426.
- Murthy, A. K.; Tam, J. M.; Tam, J. O.; Ingram, D.; Schulze, M.; Robin, N.; Stover, R.; Schramm, R.; Ma, L.; Sokolov, K. V.; Johnston, K. P.,. Design of biodegradable gold nanoclusters for NIR optical imaging. Abstracts of Papers of the American Chemical Society 242, 2011.
|Title:||Optical Systems for In Vivo Molecular Imaging of Cancer|
|Title:||Acoustic Imaging of Sentinel Node Metastasis Using Plasmonic Nanosensors|
|Title:||Biodegradable Plasmonic Nanoparticles for Cancer Imaging and Therapy|
|Title:||Functional, cellular and molecular imaging using ultrasound-guided photoacoustics,|
|Title:||iThera Medical Multispectral Optoacoustic Tomography System for Full Body Molecular and Functional Small Animal Imaging|
|Title:||Interdisciplinary Translational Pre/Postdoctoral Program in Cancer Nanotechnology|
|Title:||Development of unconventional MRI approaches to imaging cancer immunotherapy|
|Funding Source:||GE Healthcare|