Lauren Q Chang Sen, M.D.
Department of Breast Imaging, Division of Diagnostic Imaging
About Dr. Lauren Q Chang Sen
Dr. Chang Sen is an associate professor in the Department of Breast Imaging. She completed medical school at the Washington University in St. Louis. After completing residency in diagnostic radiology at the University of Pittsburgh Medical Center, she went on to complete fellowships in women's imaging at the Magee Women's Hospital of University of Pittsburgh Medical Center.
She authored multiple book chapters, research papers, and gave scientific/educational presentations at various national conferences.
Present Title & Affiliation
Primary Appointment
Associate Professor, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Lead Interpreter Physician, Breast Imaging, The University of Texas MD Anderson Cancer Center Diagnostic Imaging West Houston Breast Imaging, Houston, TX
Research Interests
Multimodality Breast Imaging
Patient and provider education and outreach
Radioactive seed localization
Clinical Interests
Breast tomosynthesis in diagnostic setting
Tomosynthesis guided intervention
Breast Ultrasound
Breast MRI
High risk screening
Education & Training
Degree-Granting Education
| 2009 | Washington University School of Medicine, St. Louis, Missouri, US, MD |
Postgraduate Training
| 2014-2015 | Clinical Fellowship, Women’s Imaging, Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania |
| 2010-2014 | Clinical Residency, Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania |
| 2009-2010 | Clinical Internship, St. Mary’s Health Center, St. Louis, Missouri |
Licenses & Certifications
| 2015 | American Board of Radiology |
| 2015 | Texas Medical License |
| 2014 | Pennsylvania Medical License |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2021
Extramural Institutional Committee Activities
Reviewer, Institutional Research Grant (IRG) Review Committee, The University of Texas MD Anderson Cancer Center, 2024 - Present
Chair, Diagnostic Imaging Research Functional Committee HALs Research Task Group, The University of Texas MD Anderson Cancer Center, 2022 - Present
Member, Diagnostic Imaging Research Functional Committee, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Breast Imaging Policy Review Committee, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Houston Area Locations Faculty CFC Subcommittee, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Houston Area Locations Expansion Operations Committee, The University of Texas MD Anderson Cancer Center, 2021 - Present
Chair, Breast Imaging Research Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Member, DI Houston Area Locations Site Medical Directors Selection Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2021
Member, Houston Area Locations Clinical Research Steering Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2021
Vice Chair, Breast Imaging Research Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2020
Member, Memorial Hermann Katy Utilization Review Committee, The University of Texas MD Anderson Cancer Center, 2017 - 2020
Member, Breast Imaging Research Committee, The University of Texas MD Anderson Cancer Center, 2015 - Present
Honors & Awards
| 2020 | Exceptional Reviewer Award, Journal of Breast Imaging, Society of Breast Imaging |
| 2013 | Cum Laude award for Electronic Exhibit, Radiological Society of North America (RSNA) |
| 2009 | Hugh M. Wilson Award in Radiology, Washington University School of Medicine |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2025. Calcifications in the treated breast after breast conserving surgery. Conference. 8th Annual Breast Imaging Essentials: Mammography, Ultrasound, MRI, and Intervention. Houston, Texas, US.
- 2023. BI-RADS Mammography. Conference. 6th Annual Breast Imaging Seminar. Houston, TX, US.
- 2022. BI-RADS Mammography and Calcifications at Lumpectomy Site. Conference. Fifth Annual MDACC Breast Imaging Technologist Seminar. Houston, TX, US.
- 2021. Ultrasound Interesting Cases. Conference. Fourth Annual MDACC Breast Imaging Technologist Seminar. Houston, TX, US.
- 2020. Calcifications at the Lumpectomy Site. Conference. Third Annual MDACC Breast Imaging Technologist Seminar. Houston, TX, US.
- 2019. Breast Cancer: Reduce Your Risks. Invited. Chi Omicron Omega Chapter of Alpha Kappa Alpha Sorority, Inc. Houston, TX, US.
- 2019. BI-RADS Update: Mammography and Audit. Conference. Second Annual MDACC Breast Imaging Technologist Seminar. Houston, TX, US.
- 2018. Breast Hands-On Workshop. Conference. The Cancer Imaging and Intervention Conference. Houston, TX, US.
- 2016. Impact of Re-Interpretation and Repeat Imaging of Breast Imaging Studies in Patients Not Previously Diagnosed with Breast Cancer. Conference. Diagnostic Radiology Research Retreat. Houston, TX, US.
- 2015. Radioactive Seed Localization: Pitfalls, Potential Issues and Precautions. Invited. Houston Radiological Society, US.
- 2015. BI-RADS Update: Mammography and Audit. Invited. Houston Radiological Society, US.
Regional Presentations
- 2015. Panel Discussion: Implementing a Multidisciplinary Approach for MBC Patients/Tumor Board Discussion. Conference. Pfizer Oncology Breast Cancer Institutional Preceptorship, US.
National Presentations
- 2025. Case of the Day. Conference. SBI 2025 Breast Imaging Symposium. Colorado Springs, Colorado, US.
- 2024. Cryoablation + Immunotherapy: What Radiologists Need To Know, Breast Cryoablation: Why, when, and How?. Conference. American Roentgen Ray Society Annual Meeting. Boston, MA, US.
- 2022. Contrast-enhanced spectral mammography for the differentiation of benign and malignant axillary lymph nodes in breast cancer staging. Conference. SBI 2022 Breast Imaging Symposium. Savannah, Georgia, US.
- 2017. Impact of Re-Interpretation and Repeat of Breast Imaging Studies. Conference. American Roentgen Ray Society 2017 Annual Meeting. New Orleans, Louisiana, US.
- 2016. Management of Two or More Distinct Sites of Indeterminate Calcifications in Women without a Concurrent Breast Cancer Diagnosis. Conference. Radiological Society of North America 102nd Scientific Assembly and Annual Meeting. Chicago, IL, US.
- 2013. Apocrine Lesions of the Breast: What Are They and What Should Radiologists Know. Conference. Radiological Society of North America 99th Scientific Assembly and Annual Meeting. Chicago, IL, US.
- 2013. The Many Faces of Sarcoidosis. Conference. Association of University Radiologists Annual Meeting. Los Angeles, California, US.
- 2012. Upstaging Rates at Surgical Excision after Core Biopsy Diagnosis of Atypical Lobular Hyperplasia or Classic Lobular Carcinoma in Situ. Conference. Radiological Society of North America 98th Scientific Assembly and Annual Meeting. Chicago, IL, US.
- 2012. Smart Nail – Not So Smart Outcome. Conference. American Roentgen Ray Society 2012 Annual Meeting. Vancouver, British Columbia, CA.
- 2012. Tendon Injuries of the Ankle: Incidence, Diagnosis and Treatment. Conference. Association of University Radiologists Annual Meeting. San Antonio, Texas, US.
- 2012. MRI of Ankle Impingement Syndromes: A Pictorial Review. Conference. Association of University Radiologists Annual Meeting. San Antonio, Texas, US.
- 2009. Value of histogram analysis for characterization of indeterminate adrenal nodules on noncontrast CT. Conference. Radiological Society of North America 95th Scientific Assembly and Annual Meeting. Chicago, IL, US.
International Presentations
- 2024. Defining efficacy in palliative breast cancer cryoablation: Beyond the ICE3 trial. Conference. SBI 2024 Breast Imaging Symposium. Montreal, CA.
Formal Peers
- 2023. Calcifications in the Treated Breast After Breast Conserving Therapy. Visiting, US.
Grant & Contract Support
| Date: | 2023 |
| Title: | 3D Printed Breast Models in the Surgical Management of Breast Cancer |
| Funding Source: | University Cancer Foundation via The University of Texas MD Anderson Cancer Center Institutional Research Grant Program |
| Role: | PI |
| ID: | 2021-1201 |
Selected Publications
Peer-Reviewed Articles
- Huang ML, Lane DL, Amini B, Chang Sen LQ, Candelaria RP, Santiago L. Cryoablation of axillary lymph node metastases for the curative and palliative treatment of breast cancer. J Breast Imaging. e-Pub 2026.
- Huang ML, Lane DL, Chang Sen LQ, Candelaria RP, Santiago L. Postcryoablation breast imaging algorithms, findings, and standardized reporting. J Breast Imaging 8(1):96-108, 2026. e-Pub 2026. PMID: 41558639.
- Huang ML, Lane DL, Chang Sen LQ, Candelaria RP, Kuerer HM, Hunt KK, Akay C, Lim B, Shaitelman S, Hwang RF, Chen H, Katta R, Santiago L. Defining breast cryoablation treatment success: a guide for the curative and palliative treatment of breast cancer. Acad Radiol 31(12):4759-4771, 2024. e-Pub 2024. PMID: 39107186.
- Speer M, Yoon EC, Berg WA, Chang Sen LQ. Pseudoangiomatous stromal hyperplasia. J Breast Imaging 5(1):67-72, 2023. e-Pub 2023. PMID: 36778653.
- Chang Sen L, Ko A, Patel MM, Leung JWT. Time to development and imaging features of new calcifications in the treated breast after breast-conserving therapy. Breast J 27(10):761-767, 2021. e-Pub 2021. PMID: 34363281.
- Shu H, Chiang T, Wei P, Do K, Lesslie MD, Cohen EO, Srinivasan A, Moseley TW, Chang Sen LQ, Leung JWL, Dennison JB, Hanash SM, Weaver OO. A deep learning approach to re-create raw full-field digital mammograms for breast density and texture analysis. Radiol Artif Intell 3(4), 2021. e-Pub 2021. PMID: 34350403.
- Chang Sen LQ, Mayo RC, Leung JWT. Concerns about the economics of mammography and how radiologists can respond. Clin Imaging 66:84-86, 2020. e-Pub 2020. PMID: 32460152.
Abstracts
- Mayo RC, Le-Petross H, Chang Sen LC, Phalak K, Whitman G, Yang W. Potential Management Changes when Radiologist Assigned BI-RADS 3 Sonographic Lesions are Reviewed With AI Decision Support. American Roentgen Ray Society Annual Meeting, 2025. e-Pub 2025.
Patient Reviews
CV information above last modified July 22, 2026