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      Lei Chen Image

      Lei Chen, MD

      Department of Laboratory Medicine, Division of Pathology-Lab Medicine Div

      Present Title & Affiliation

      Dual/Joint/Adjunct Appointment

      Professor, Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

      Education & Training

      Postgraduate Training

      2014-2015Laboratory Medical Program, Laboratory Medical Director Advanced Practical Pathology Program, College of American Pathologists (CAP), Chicago, Illinois
      2012-2013Clinical Safety Program, Vice Chair for Clinical Safety & Effectiveness Program, UT Medical School and Memorial Hermann, Houston, Texas
      2005-2006Fellowship, Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas
      2001-2005Clinical Residency, Department of Pathology and Laboratory Medicine, The University of Texas Medical Branch at Galveston, Galveston, Texas

      Licenses & Certifications

      2017American Board of Medical Quality
      2017Laboratory Medical Director Certificate, CAP
      2007Texas Medical License
      2006American Board of Pathology, Hematology Board
      2005American Board of Pathology, AP/CP

      Experience & Service

      Faculty Academic Appointments

      Professor, Pathology/Laboratory Medicine, The University of Texas Medical School-Houston, Houston, TX, 2021 - 2022

      Associate Professor, Pathology/Laboratory Medicine, The University of Texas Medical School-Houston, Houston, TX, 2012 - 2021

      Assistant Professor, Pathology/Laboratory Medicine, The University of Texas Medical School-Houston, Houston, TX, 2007 - 2012

      Assistant Professor, Pathology, The University of Arkansas for Medical Sciences (UAMS), Little Rock, AR, 2006 - 2007

      Editorial Activities

      Board Member and Reviewer, Journal of Clinical & Experimental Pathology, 2011 - Present

      Honors & Awards

      2021Texas Society of Pathologists Poster Presentation, Texas Society of Pathologist
      2020ASCP 2020 Virtual Annual Meeting, American Society for Clinical Pathology
      2015Consultative Algorithmic Workups for Rheumatology
      2008Innovation Award Physician Winner for Lab Innovation, Lyndon B. Johnson General Hospital
      2005Departmental Research Training Scholarship, University of Texas Medical Branch- Texas Society of Pathologists
      1997Research Training Grant from National Institute for Occupational Safety and Health

      Selected Presentations & Talks

      Local Presentations

      1. 2019. A Case Report in the Workshop of Society for Hematopathology and European Association for Hematopathology. Invited. Houston, Texas, US.
      2. 2019. Application of Deep Learning to Automated Diagnosis of Lymphoma with Digital Pathology Images. Invited. Data Science Conference at Rich University. Houston, TX, US.
      3. 2016. Multidisciplinary approach to improve access of care for Systemic Lupus Erythematosus patients at Harris Health System. Shared Visions: Improving Systems to Improve Lives, a part of ‘UT System Clinical Safety and Effectiveness Program. San Antonio, TX, US.

      Regional Presentations

      1. 2023. Interpreting B-cell clonality in Exceptional Conditions: A Case Report of B-cell Lymphoma. Invited. Texas Society of Pathology Annual Meeting, US.
      2. 2021. The involvement of bilateral parotid lymphoepithelial cysts as the initial presentation of T-cell prolymphocytic leukemia with t(X;14)(q28;q11). OnlineOnly. Texas Society of Pathology Annual Meeting, US.
      3. 2017. Unusual Presentation of Hairy Cell Leukemia without Splenomegaly. Invited. Texas Society of Pathologists Annual Meeting. Bastrop, TX, US.
      4. 2017. Acute Promyelocytic Leukemia with Unusual Presentation. Invited. Texas Society of Pathologists Annual Meeting. Bastrop, TX, US.
      5. 2015. Clinical History, Cause of Death, Laboratory and Autopsy Findings of Patients with Undiagnosed Hematological Malignancy: A Retrospective Study. Invited. 105th Annual Meeting of Texas Society Pathology. San Antonio, TX, US.
      6. 2013. Extracavitary Primary Effusion Lymphoma in an Axillary Lymph Node: Case Report and Literature Review. Invited. Annual Meeting of Texas Society of Pathologists. Plano, TX, US.
      7. 2010. Systemic Mastocytosis and Co-existing Plasma Cell Neoplasm. Poster. 89th Annual Meeting of Texas Society of Pathologists 2010. Galveston, TX, US.
      8. 2010. MALT Lymphoma of the Salivary Gland with Aberrant CD5 Expression and an Unusually Aggressive Clinical Course: A Case Report. Poster. 89th Annual Meeting of Texas Society of Pathologists 2010. Galveston, TX, US.
      9. 2010. An Unusual Case Report: Acute Lymphoblastic Leukemia from a Patient with Previously Treated Multiple Myeloma. Poster. 89th Annual Meeting of Texas Society of Pathologists. Galveston, TX, US.
      10. 2009. Primary, Extranodal Classical Hodgkin Lymphoma involving the Bone Marrow. Poster. 88th Annual Meeting of Texas Society of Pathologists. Austin, TX, US.
      11. 2009. T-cell Lymphoma with Splenic Rupture in a Patient with Colonic Adenocarcinoma. Poster. 88th Annual Meeting of Texas Society of Pathologists. Austin, TX, US.
      12. 2008. Intravascular Large B-cell Lymphoma, a Report of Two Cases. Poster. 87th Annual Meeting of Texas Society of Pathologists. Houston, TX, US.
      13. 2008. Idiopathic Scrotal Calcinosis. Poster. 87th Annual Meeting of Texas Society of Pathologists. Houston, TX, US.
      14. 2005. Fatal Hemorrhage Secondary to Ulcerated Epiphrenic Pseudodiverticulum Autopsy Case Report with Clinical and Radiologic Correlation. Conference. 84th Annual Meeting of Texas Society of Pathologists (TSP). Austin, Texas, US.
      15. 2005. Identification of Biomarkers for Systemic Streptococcus and Staphylococcus Infections by Proteomic Analysis. Conference. 84th annual meeting of Texas Society of Pathologists. Austin, TX, US.
      16. 2005. Biomarker Identification for Testicular Tumor Using Cation-Exchange Protein Chip. Conference. 84th Annual Meeting of Texas Society of Pathologists. Austin, Texas, US.

      National Presentations

      1. 2025. Artificial Intelligence-Assisted Image Analysis of Peripheral Blood Smears to Aid in the Diagnosis and Monitoring of Acute Promyelocytic Leukemia. Invited. USCAP Annual Pathology Meeting, US.
      2. 2025. Clinicopathological Overlap Between Primary and Secondary Plasma Cell Leukemia: Implications for Lowering the Diagnostic Threshold for Circulating Plasma Cells. Invited. USCAP Annual Pathology Meeting, US.
      3. 2023. A 20-year Retrospective Autopsy Study of 50 Patients with Hematological Malignancies from a Single Institution. Invited. USCAP Annual Pathology Meeting, US.
      4. 2023. The Clinicopathologic Features of Primary Epidural B-Cell Lymphoma. Invited. USCAP Annual Pathology Meeting, US.
      5. 2021. Diagnostic and Prognostic Roles of EBV Infection in Patients with HIV-Associated Aggressive Non-Hodgkin Lymphomas in the Era of HAART. OnlineOnly. USCAP Annual Pathology Meeting, US.
      6. 2020. Pylori negative Primary Gastric Mucosa-associated Lymphoma (MALToma) more often associated with Obesity, a single-institution study. Invited. USCAP Annual Pathology Meeting. Los Angeles, CA, US.
      7. 2019. High-grade B-cell lymphoma is associated with a worse survival than other aggressive B-cell lymphoma in HIV+ patients. Invited. USCAP Annual Pathology Meeting. Washington, DC, US.
      8. 2019. HIV-Associated Plasmablastic Lymphoma: Ten-Year Experience in the Era of Highly Active Antiretroviral Therapy. Invited. USCAP Annual Pathology Meeting. Washington, DC, US.
      9. 2018. Image guided Bone marrow biopsies: Pathological comparison of marrow specimen quality obtained using a Mallet versus without. Invited. SIR Annual Meeting. Philadelphia, PA, US.
      10. 2016. Effects of the use of a hammer/mallet during bone marrow biopsy collection on specimen quality: A Quality Improvement Project. Invited. USCAP Annual Pathology Meeting. Seattle, WA, US.
      11. 2015. Improving Access to Specialty Care for Rheumatologic Conditions by Implementation of Algorithmic Testing and Clinical Pathology Supervision and Consultation. Invited. 50th Annual ACLPS Meeting. Minneapolis, MN, US.
      12. 2015. Clinical History, Cause of Death, Laboratory and Autopsy Findings of Patients with Undiagnosed Hematological Malignancy: A Retrospective Study. Invited. USCAP Annual Pathology Meeting. Boston, MA, US.
      13. 2015. Myeloid and Lymphoid Neoplasms with Eosinophilia and Translocations of Fibroblast Growth Factor Receptor 1: A Morphoproteomic Analysis of 12 Patients Reveals Potential Therapeutic targets. Invited. USCAP Annual Pathology Meeting. Boston, MA, US.
      14. 2014. Transforming Outpatient Laboratory Medicine: Ongoing UT-Houston – Harris Health Experience. Invited. Association of Clinical Scientists Annual Meeting, US.
      15. 2012. CD5 positive Nodal Marginal B-cell lymphoma, a Clinicopathologic studies of 8 cases. Poster. USCAP Annual Pathology Meeting. Vancouver, CA.
      16. 2012. Utility of Bone Marrow Examination for Workup of Fever in HIV patients. Poster. USCAP Annual Pathology Meeting. Vancouver, CA.
      17. 2011. CD5 Positive MATL Lymphoma, a Clinicopathologic Studies of 9 Cases. Poster. US and Canadian Annual Pathology Meeting. San Antonio, TX, US.
      18. 2009. Hematologic Manifestations of Copper Deficiency: One Year Experience of a Single Institution. Poster. US and Canadian Annual Pathology Annual Meeting. Boston, MA, US.
      19. 2006. Secondary Cytogenetic Aberrations Do Not Affect Survival in Acute Myeloid Leukemia (AML) with t(8;21)(q22;q22). Poster. US and Canadian Annual Pathology Meeting. Atlanta, GA, US.
      20. 2006. Clinical Implications of Quantitative and Qualitative Post-Treatment Detection of AML1-ETO in AML. Poster. US and Canadian Annual Pathology Meeting. Atlanta, GA, US.
      21. 2005. Identification of Biomarkers for Systemic Streptococcus and Staphylococcus Infections by Proteomic Analysis. Conference. US and Canadian Annual Pathology Annual Meeting. San Antonio, TX, US.
      22. 2005. Expression of PAX5/B-cell specific activation protein (BSAP) in acute myeloid leukemia associated with t(8;21)(q22;q22). Conference. US and Canadian Annual Pathology Annual Meeting. San Antonio, Texas, US.
      23. 2005. Biomarker Identification for Testicular Tumor Using Cation-Exchange Protein Chip. Conference. US and Canadian Annual Pathology Annual Meeting. San Antonio, Texas, US.

      International Presentations

      1. 2022. Plasma cell neoplasm with initial presentation as an ovarian mass: a rare case report. Invited. ASCP Annual Meeting. Chicago, US.
      2. 2022. Uncommon variant of CD4+ T-cell large granular lymphocytic leukemia. Invited. ASCP Annual Meeting. Chicago, US.
      3. 2022. Clinicopathologic Findings of Patients with Undiagnosed Hematologic Malignancies: a Retrospective Autopsy Study. Invited. CAP Annual Meeting, US.
      4. 2022. HHV8-negative effusion-based lymphoma in a patient with a liver transplantation. Invited. 21st Meeting of the European Association for Hematopathology. Florence, IT.
      5. 2021. Kikuchi-Fujimoto Disease as M2 Polarized Disorder with Therapeutic Implications: a Morphoproteomic Study. OnlineOnly. CAP Annual Meeting, US.
      6. 2020. Langerhans Cell Sarcoma Following Follicular Lymphoma: Evidence of Transdifferentiation. OnlineOnly. CAP Annual Meeting, US.
      7. 2020. Discordant Lymphoma in a HIV/AIDS patient: A Sequential Case of EBER+ lymphomas in different subtypes. (Burkitt Lymphoma and Classic Hodgkin Lymphoma). OnlineOnly. ASCP Annual Meeting-, US.
      8. 2020. A Challenging Case of a Myeloid Sarcoma Mimicking ‘High Grade B-Cell Lymphoma. OnlineOnly. ASCP Annual Meeting, US.
      9. 2020. Dasatinib Plus Chemotherapy in Core Binding Factor Leukemia: A Case Study. Invited. SOHO 2020 Annual Meeting. Houston, US.
      10. 2020. Durable Response of a Patient with a Mantle Cell Lymphoma Central Nervous System (CNS) Relapse to Treatment with a Bruton Tyrosine Kinase Inhibitor (BTKi) Monotherapy. Invited. SOHO 2020 Annual Meeting. Houston, US.
      11. 2020. Treatment of High-Grade Diffuse Large B- Cell Lymphoma (HG-DLBCL) of the Elderly with Lenalidomide, Rituximab, Cyclophosphamide, and Prednisone. Invited. SOHO 2020 Annual Meeting. Houston, US.
      12. 2019. Deep learning and automated diagnosis of Lymphoma with whole slide imaging. Invited. Annual Meeting of Digital Pathology Association. Orlando, US.
      13. 2019. Acute Leukemia and Pregnancy: Thirty-two weeks pregnant patient with Acute Myeloid Leukemia and a patent foramen ovale. The importance of a multidisciplinary approach. Invited. 7th Annual Meeting of the Society of Hematologic Oncology (SOHO). Houston, US.
      14. 2019. The Pathogenesis between Alpha-1 Antitrypsin Deficiency and JAK2 V617F Mutation. Invited. CAP Annual Meeting. Orlando, US.
      15. 2019. An Incidental Finding of Helicobacter pylori-Negative Gastric MALT Lymphoma in a Sleeve Gastrectomy Specimen: An Emphasis on Grossing and Sampling Techniques. Invited. CAP Annual Meeting. Orlando, US.
      16. 2018. Acute Leukemia of Ambiguous Lineage Presenting with Retroperitoneal Lymphadenopathy. Invited. CAP Annual Meeting. Chicago, US.
      17. 2018. Acute Promyelocytic Leukemia with Cryptic PML-RARA Rearrangement. Invited. CAP Annual Meeting. Chicago, US.
      18. 2018. Predicting Prognosis of Acute Myeloid Leukemia with Deep Learning Analysis. Invited. CAP Annual Meeting. Chicago, US.
      19. 2018. Fatal intracranial hemorrhage in a pregnant patient with acute promyelocytic leukemia: a case report. Invited. ASCP Annual Meeting. Baltimore, US.
      20. 2018. Aleukemic myeloid sarcoma in female reproductive system: report of two rare cases. Invited. ASCP Annual Meeting. Baltimore, US.
      21. 2018. Acute Myeloid Leukemia with APL-like immunophenotype: a case series. Invited. ASCP Annual Meeting. Baltimore, US.
      22. 2018. Automated Diagnosis of Lymphoma with Digital Pathology Images Using Deep Learning. Invited. CAP Annual Meeting. Chicago, US.
      23. 2018. Immunophenotypic profiles of primary mediastinal (Thymic) Large B-cell lymphoma. Invited. 33rd Annual Clinical Cytometry Meeting. Portland, US.
      24. 2018. First report of deep gene sequencing in two patients with brain myeloid sarcoma’. Invited. Sixth Annual SOHO 2018 Meeting. Houston, US.
      25. 2018. Carfilzomib, a potential front line therapy for hyperviscosity syndrome associated to plasma cell dyscrasia. Invited. Sixth Annual SOHO 2018 Meeting. Houston, US.
      26. 2018. Decitabine in combination with venetoclax in six elderly patients with acute myeloid leukemia (AML). Invited. Sixth Annual SOHO 2018 Meeting. Houston, US.
      27. 2018. Placental involvement by Acute Promyelocytic Leukemia during initial presentation of the disease. Invited. ACS Annual Meeting. Houston, US.
      28. 2017. CNS infections may present as CSF mono/oligoclonal bands. Invited. CAP Annual Meeting, US.
      29. 2017. Triple-Hit B-Cell Lymphoma with translocations of Cyclin D1, MYC, and BCL6: A novel entity. Invited. CAP Annual Meeting. National Harbor, US.
      30. 2017. Proteomics Analysis of FLT3-ITD in AML using Deep Learning Neural Network. Invited. ASCP Annual Meeting, US.
      31. 2017. Unique Pediatric Case Of Relapsing B- Acute Lymphoblastic Leukemia Presenting With Third Degree Heart Block. Invited. ASCP Annual Meeting, US.
      32. 2017. Unusual Presentation of Hairy Cell Leukemia without Splenomegaly. Invited. CAP Annual Meeting. National Harbor, US.
      33. 2014. Improving Clinical and Cost Efficiency of Peripheral Blood Smear Review. Invited. ASCP Annual Meeting. Tampa, US.
      34. 2013. P. Falciparum Recurrence Two Years After Exposure in Endemic Country: A Case Report. Invited. ASCP Annual Meeting. Chicago, US.
      35. 2013. Morphoproteomics Study of a Rare Case of Myeloid and Lymphoid Neoplasm with Eosinophilia and FGFR1 Abnormality. Invited. ASCP Annual Meeting. Plano, US.
      36. 2013. Perifollicular Granulomas with IgG4 Plasmacytosis: A Case Report. Invited. CAP Annual Meeting, US.
      37. 2012. Comparison of Bone Marrow Abnormalities of Two HIV/AIDS Patient Populations. Invited. CAP Annual Meeting, US.
      38. 2011. A Testing Panel for Lupus Anticoagulant with Improved Sensitivity. Poster. CAP Annual Meeting, US.
      39. 2010. Expression of Immunoglobulin Gene in Myeloblasts from Patients with Acute Myelogenous Leukemia and its Distinct VKJK Recombination Pattern. Poster. AACR Annual Meeting. Washington, D.C, US.
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      Selected Publications

      Peer-Reviewed Articles

      1. Wang WJ, Hu Z, Chen L, Gehris BT, Naik U, Bhattacharjee BB, Wahed MDA, Hu S, You MJ, Wang W, Medeiros LJ. Clinicopathological Features of Primary Epidural B-cell Lymphoma: A Study of 14 Cases. Pathology 58(1):24-29, 2026. e-Pub 2025. PMID: 41062339.
      2. Shuai, W, Hu, Z, Yin, CC, Chen, L, Wang, W, Tang, G, Sui, D, Li, S, Xu, J, Ibrahim, NE, Pan, Z, You, MJ, Patel, KP, Vega Vazquez, F, Medeiros, LJ, Lin, P. Lowering the Diagnostic Threshold in Secondary Plasma Cell Leukemia? Comparison With Primary Cases and Implications for Flow Cytometry Immunophenotyping. Modern Pathology 39(2), 2026. e-Pub 2026. PMID: 41456722.
      3. Arana Rosainz, MJ, Nguyen, ND, Wahed, A, Lelenwa, L, Aakash, N, Schaefer, K, Rios, A, Kanaan, Z, Chen, L. Acute myeloid leukemia with mutated NPM1 mimics acute promyelocytic leukemia presentation. International Journal of Laboratory Hematology 43(2):218-226, 2021. e-Pub 2021. PMID: 33099879.
      4. Mai, B, Friscia, M, Elzamly, S, Thomas-Ogunniyi, J, Wahed, A, Nguyen, ND, Hu, Z, Cai, Z, Chen, L. Obesity Is a Risk Factor Associated with H. pylori-negative MALT Lymphoma of Stomach. Annals of clinical and laboratory science 51(5):609-614, 2021. e-Pub 2021. PMID: 34686502.
      5. Shaui W, Hu Z, Yin CC, Chen L, Wang W, Tang G, Li S, Xu J, Ibrahim N, Pan Z, You MJ, Patel KP, Vega F, Medeiros LJ, Lin P. Comparing Primary and Secondary Plasma Cell Leukemia: Implications for Flow Cytometry Immunophenotyping and Lowering the Diagnostic Threshold. Modern Pathology.
      6. Chen L, Shi A, Liu JM, Subash KM, Liu J, Chen E, Han X, Wang W, Medeiros LJ, Shaui W, Mai B, Zheng M, Yuan J, Pan Z, Hu R, Quesada AE, Fu X, Wang SA, Tang G, Bueso-Ramos CE, You MJ, Hansel DE, Borthakur G, Hirsch Ginsberg CF, Hu S, Sun X, Wu J, Hu Z. AI-Enhanced Peripheral Blood Smear Analysis Enables Accurate Diagnosis and Monitoring of Acute Promyelocytic Leukemia: Multicenter Validation Across Real-World Cohorts. Nature Communications.

      Other Articles

      1. Chen, L, Jaitly, V Hairy Cell Leukemia with Unusual Presentation, 2018. PMID: 29678856.
      2. Abruzzo, LV, Chen, L, Estrov, Z, Huang, RS, Idowu, M, Juneja, H, Ohanian, M, Yakoushina A, T Isolated Mesenteric CD20-Poaitive Myeloid Sarcoma, 2014. PMID: 25131853.

      Abstracts

      1. Baxter, AJ, Chen, L, Golardi, N, Kott, MM, Mauzo, SH, Nguyen, ND, Sultana, S, Zhang, R, Zvavanjanja, RC. Effects of the Use of a Mallet during Bone Marrow Biopsy Collection on Specimen Quality: A Quality Improvement Project, 2018. e-Pub 2018. PMID: 30143496.
      2. Alhalabi, O, Chen, L, Wei, Wei C, C. T-Cell/ Histiocyte-rich Large B-Cell Lymphoma in a Child: A Case Report and Review of Literature, 2018. e-Pub 2018. PMID: 29988902.
      3. Carroll, K, Chang, B, Chen, L, Hunter, R, Kidd, L, Kott, M, McKee, D, Nguyen, A, Pung, N, Risin, S, Tholpady, A, Wahed, A, Welsh, KJ, Zare, M. Algorithmic Approach with Clinical Pathology Consultation Improves Access to Specialty Care for Systemic Lupus Erythematosus Patients, 2016. e-Pub 2016. PMID: 27510715.
      4. Al-Ibraheemi, A, Chen, L, Dierksen, J, Wagner, A. Plasmodium Falciparum Recurrence Two Years After Exposure in Endemic Country, 2016. e-Pub 2016. PMID: 27466306.
      5. Bueso-Ramos, CE, Chen, L, He, Z, Hu, Qiu, X, Sun, X, Wang, C, Xia, M, Yin A, CC. IGK with Conserved IGKV/IGKJ Repertoire is Expressed in Acute Myeloid Leukemia and Promotes Leukemic Cell Migration, 2015. e-Pub 2015. PMID: 26429876.
      6. Chen, L, Liang, L, Zhou, J. Perifollicular Granulomas with IgG4 Plasmacytosis: A Case Report and Review of Literature, 2015. e-Pub 2015. PMID: 26244157.
      7. Chang, B, Chen, L, Hunter, R, Kidd, Knott, M, L, Moreno, V, Nguyen, N, Tholpady, A, Risin, SA, Wahed, A, Welsh A, K. Exploring New Ways to Deliver Value to Healthcare Organizations: Algorithmic Testing, Data Integration, and Diagnostic E-consult Service, 2015. e-Pub 2015. PMID: 26116586.
      8. Chen, L, Nguyen, A, Quesada, A, Tholpady, A, Wagner A, A. Utility of Bone Marrow Examination for Workup of Fever of Unknown Origin in HIV/AIDS Patients, 2015. e-Pub 2015. PMID: 25589792.
      9. Baljevic M, Chen, L, Hashemi-Sadraei, N, Idowu, M, Vejpongsa A, P. Epstein Barr Virus-related Hemophagocytic Lymphohistiocytosis: Hematologic Emergency in the Critical Care Setting, 2015. e-Pub 2015. PMID: 25755898.
      10. Buja, LM, Chen, L, Dierksen, J. Clinicopathologic Findings of Hematological Malignancy: A Retrospective Autopsy Study, 2015. e-Pub 2015. PMID: 26586710.
      11. Chen, L, Jabcuga CE, Jaso, JM, Medeiros, LJ, Miranda, RN, Wang, SA, Yin A, CC. Clinicopathologic Features of CD5-Positive Nodal Marginal Zone Lymphoma, 2013. e-Pub 2013. PMID: 24124149.
      12. Chen, L, He, Z, Hu, F, Huang, J, Medeiros, J, Pei, L, Qui, X, Sun, X, Yin, C, You A, J. Immunoglobulin Gamma Heavy Chain Gene with Somatic Hypermutation is Frequently Expressed in Acute Myeloid Leukemia:27,92-99, 2013. e-Pub 2013. PMID: 22772058.
      13. Chen, L, Gonzalez, M, Kidd, L, Nguyen, N, Quesada A, J. An Unusual Case Report: Acute Lymphoblastic Leukemia in an Patient with Previously Treated Multiple Myeloma, 2013. e-Pub 2013. PMID: 23694793.
      14. Chen, L, Chen, W, Jaso, J, Konoplev, S, Li, S, Lin, P, Medeiros, LJ, Miranda, RN, Yin A, CC. CD5-Positive Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma: A Clinicopathologic Study of 14 Cases, 2012. e-Pub 2012. PMID: 22406370.
      15. Brown, RE, Chen, L, Duan, X, Feng, W, Lapus, A, Nguyen, N, Shen A, Q. Intravascular Large B-Cell Lymphoma Report of these Cases and Analysis of them mTOR Pathway, 2011. e-Pub 2011. PMID: 22135726.
      16. Chen, L, Green, LK, Lai, S, Merritt A, BY. Hemophagocytic Lymphohistiocytosis Associated with Influenza A (H1N1) Infection in a Patient with Chronic Lymphocytic Leukemia: An Autopsy Case Report and Review of the Literature, 2011. e-Pub 2011. PMID: 21724431.
      17. Brown, RE, Chen, L, Duan, X, Lapus A, A. Intravascular Large B-Cell Lymphoma Presenting as Cholecystitis and Pancytopenia: Case Report with Literature Review, 2011. e-Pub 2011. PMID: 22075510.
      18. Brown, RE, Chen, L, Duan, X, Feng, W, Ramondetta, L, Rodriguez, ME, Shen, Q, Stanton, ML. Morphoproteomic Analysis Reveals an Overexpressed and Constitutively Activated Phospholipase D1-mTORC2 Pathway in Endometrial Carcinoma, 2010. e-Pub 2010. PMID: 21228924.
      19. Brown, RE, Chen, L, Dhingra, S, Duan, X, Rodriguez, ME, Shen, Q, Stanton, ML, Zhang A, R. Constitutive Activation with Overexpression of the mTORC2-Phospholipase D1 Pathway in Uterine Leiomyosarcoma and STUMP: Morphoproteomic Analysis with Therapeutic Implications, 2010. e-Pub 2010. PMID: 21326806.
      20. Abruzzo, LV, Chen, L, Chen, SS, Gustafson, SA, Lin, P, Luthra, R, Medeiros LJ, Wang A, SA. Therapy-Related Acute Myeloid Leukemia with T(8;21)(Q22;Q22) Shares Many Features with De Novo Acute Myeloid Leukemia with T(8;21)(Q22;Q22) but Does Not Have A Favorable Outcome, 2009. e-Pub 2009. PMID: 19369623.
      21. Chen, L, Konoplev, S, Lin, P, Luthra, P, Medeiros, JF, Wang, X. Acute Myeloid Leukemia Harboring T(8;21)(Q22;22) a Heterogeneous Disease with Poor Outcome in a Subset of Patients Unrelated to Secondary Cytogenetic Aberrations, 2008. e-Pub 2008. PMID: 18536654.
      22. Chen, L, Lin, P, Medeiros, LJ, Rassidakis, GZ, Valbuena, JR. Expression of B Cell Specific Activator Protein/PAX5 in Acute Myeloid Leukemia t(8;21)(q22;q22), 2006. e-Pub 2006. PMID: 16891199.
      23. Chen, L, Schnadig, V, Walser, E. Fatal Hemorrhage Secondary to Ulcerated Epiphrenic Pseudodiverticulum, 2006. e-Pub 2006. PMID: 16740042.
      24. Chen, L, Dinh, TA, Haque, A. Small Cell Carcinoma of the Ovary with Hypercalcemia and Ectopic Parathyroid Hormone Production, 2005. e-Pub 2005. PMID: 15794681.
      25. Brown, CA, Chen, L, Matzuk, MM, Wu, X. Interrelationship of Growth Differentiation Factor 9 and Inhibin in Early Folliculogenesis and Ovarian Tumorigenesis in Mice, 2004. e-Pub 2004. PMID: 15016837.
      26. Ango, JE, Burns, KH, Chen, L, Haupt, B, Korach, KS, Matzuk, MM, Ogbonna, SC. Sexually Dimorphic Roles of Steroid Hormone Receptor Signaling in Gonadal Tumorigenesis, 2003. e-Pub 2003. PMID: 12855748.
      27. Cipriano, SC, Chen, L, Burns, KH, Koff, A, Matzuk A, MM. Inhibin and p27 Interact to Regulate Gonadal Tumorigenesis, 2001. e-Pub 2001. PMID: 11376116.
      28. Cipriano, SC, Chen, L, Kumar TR, Matzuk, MM. Follistatin is a modulator of gonadal tumor progression and the activin-induced wasting syndrome in inhibin-deficient mice, 2000. e-Pub 2000. PMID: 10875231.

      Letters to the Editor

      1. Rivera, D, Naik, U, Wang, WJ, Cuglievan, B, Yin, CC, Chen, L. Acute myeloid leukemia with inversion 16 and a novel PTPN11 mutation. International Journal of Laboratory Hematology 46: 195-198, 2024.
      2. Gehris, BT, Wang, WJ, Mai, B, Chen, L, Wang, W, Hu, Z. Initial classic Hodgkin lymphoma and subsequent diffuse large B-cell lymphoma. Pathology 56: 115-118, 2024.
      3. Wang, WJ, Gehris, BT, Ahmed, AA, Naik, U, Chen, L. Dual expression of surface immunoglobulin light chains is real. International Journal of Laboratory Hematology 45: e64-e67, 2023.
      4. Wang, W, Mai, B, Ali, H, Savariya, BU, Chen, L. Primary bone marrow Epstein–Barr virus-associated polymorphic B-cell lymphoproliferative disorder. International Journal of Laboratory Hematology 44: e224-e226, 2022.
      5. Ghosh, A, Chen, L, Wahed, A, Wang, W, Saluja, K, Nguyen, ND, Hu, S, Hu, Z. Incidental but rapidly progressing T-cell prolymphocytic leukemia with t(X;14)(q28;q11) involving parotid lymphoepithelial cysts. International Journal of Laboratory Hematology 44: e17-e20, 2022.
      6. Wang, WJ, Omo-Ogboi, AC, Rivera Rivera, X, Moosvi, AM, Chen, L. Bone primary, spindle cell variant of diffuse large B-cell lymphoma presenting in the femur from a Paget’s disease patient. Leukemia and Lymphoma 63: 1765-1767, 2022.
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