
Linda Pak, MD
Department of Breast Surgical Oncology, Division of Surgery
Education & Training
Degree-Granting Education
2013 | University of Michigan, Ann Arbor, Michigan, US, Medicine, Doctorate of Medicine (MD) |
2009 | University of Washington, Seattle, Washington, US, Biology/Physiology, Bachelor of Science (BS) |
Postgraduate Training
2021-2022 | Breast Surgery Fellow, Breast Surgical Oncolgy, Memorial Sloan Kettering Cancer Center, New York, New York |
2018-2021 | Categorical General Surgery Residency, Brigham and Women’s Hospital / Harvard Medical School, Boston, Massachusetts |
2017-2018 | Clinical Research Fellowship, Clinical Research, The University of Texas MD Anderson Cancer Center, Boston, Massachusetts |
2015-2016 | Certificate in Clinical Research Methodology, Clinical Research, Weill Cornell Medical College, New York, New York |
2015-2017 | Clinical Research Fellowship, Clinical Research, Memorial Sloan Kettering Cancer Center, New York, New York |
2013-2015 | Categorical General Surgery Residency, General Surgery, Barnes-Jewish Hospital / Washington University in St. Louis, St. Louis, Missouri |
Board Certifications
2022 | American Board Of Surgery |
Honors & Awards
2023 - 2025 | Shifrin-Meyers Breast Cancer Discovery Fund, NYU (New York University) |
2020 - 2021 | Brigham and Women’s Hospital General Surgery Administrative Chief Resident, Brigham and Women’s Hospital |
2020 | Society of Asian Academic Surgeons (SAAS) Resident Development Scholarship, Society of Asian Academic Surgeons (SAAS) |
Selected Publications
Peer-Reviewed Articles
- Pak L, Matar R, Argueta FV, Haglich K, Sevilimedu V, Nelson JA, Gemignani ML. Long-term patient-reported outcomes comparing oncoplastic breast surgery and conventional breast-conserving surgery. Ann Surg Oncol 30(12):7091-7098, 2023. e-Pub 2023.
- Miah PA, Pourkey N, Marmer A, Seydalis A, Fiedler L, DiMaggio C, Pak L, Shapiro R, Hiotis K, Axelrod D, Guth A, Schnabel F. Results of magnetic resonance imaging screening in patients at high risk for breast cancer. Ann Surg Oncol 30(10):6275-6280, 2023. e-Pub 2023.
- Keng KG, Witowski J, Gv KK, Yeung F, Kim M, Kim J, Pleasure M, Moczulski C, Lopez LJL, Zhang H, Harbi MA, Shamout FE, Major VJ, Heacock L, Moy L, Schnabel F, Pak L, Shen Y, Geras KJ. Improving information extraction from pathology reports using named entity recognition. Res Sq, 2023.
- Midya A, Chakraborty J, Srouji R, Narayan RR, Boerner T, Zheng J, Pak L, Creasy JM, Escobar LA, Harrington KA, Gonen M, D'Angelica MI, Kingham TP, Jarnagin WR, Do RKG, Simpson AL. Computerized diagnosis of liver tumors from CT scans using a deep neural network approach. IEEE J Biomed Health Inform 27(5):2456-2464, 2023. e-Pub 2023.
- Jolissaint JS, Want T, Soares KC, Chou JF, Gonen M, Pak LM, Boerner T. Machine learning radiomics can predict early liver recurrence after resection of intrahepatic cholangiocarcinomas. HPB 24(8):1341-50, 2022. e-Pub 2022.
- Kim HJ, Dominici L, Rosenberg SM, Zheng Y, Pak L, Poorvu PD, Ruddy KJ, Tamimi R, Schapira L, Come SE, Peppercorn J, Borges VF, Warner E, Vardeh H, Collins LC, Gaither R, King TA, Patridge AH. Surgical treatment after neoadjuvant systemic therapy in young women with breast cancer: results from a prospective cohort study. Annals of Surgery 276(1):173-179, 2022. e-Pub 2022.
- Pak L, Pawloski KR, Sevilimedu V, Kalvin H, Le T, Tokita HK, Tadros A, Van Zee KJ, Kirstein L, Moo TA. How much pain will I have after surgery? A preoperative nomogram to predict pain following mastectomy. Ann Surg Oncol 29(11):6706-6713, 2022. e-Pub 2022.
- Pak L, Purand CC, Nadipally S, Rao MP, Mukherjee S, Hedge SKB, Golshan M. Cancer awareness and stigma in rural Assam India: baseline survey of the Detect Early and Save Her/Him (DESH) program. Ann Surg Oncol 28(12):7006-7013, 2021. e-Pub 2021.
- Boerner T, Pak L, Doussot A, Drill E, Goldman DA, Gonen M, Allen PJ, Balachandran VP, Cercek A, Harding J, Solid D, D'Angelica MI, DeMatteo RP, Drebin J, Kemeny NE, Kingham TP, Simpson AL, Hecktman JF, Vakiani E, Sigel CS, Lowery MA, Ijermans J, Buttner S, Koerkamp BG, Doukas M, Jarnagin WR. Genetic determinants of outcome in intrahepatic cholangiocarcinoma. Hepatology 74(3):1429-1444, 2021. e-Pub 2021.
- Pak L, Rosenberg SM, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Snow C, Collin L, King TA, Partridge AH. Tumor phenotype and concordance in synchronous bilateral breast cancer in young women. Breast Cancer Res Treat 186(3):815-821, 2021. e-Pub 2021.
- Pak LM, Banaag A, Koehlmoos TP, Haider AH, Learn PA. Non-clinical drivers of variation in preoperative MRI utilization for breast cancer. Ann Surg Oncol 27(9):3414-3423, 2020. e-Pub 2020.
- Chawla A, Molina G, Pak LM, Rosenthal M, Mancias JD, Clancy T, Wolpin BM, Wang J. Neoadjuvant treatment is associated with improved survival in borderline resectable pancreatic cancer. Ann Surg Oncol 27(4):1191-1200, 2020. e-Pub 2020.
- Pak L, Kwon NK, Baldini EH, Learn PA, Koehlmoos T, Haider AH, Raut CP. Racial differences in the treatment of extremity soft-tissue sarcoma in a universally-insured population. J Surg Res 250:125-134, 2020. e-Pub 2020.
- Mahvi DA, Pak LM, Fields AC, Urman RD, Gold JS, Whang EE. Prediction of discharge destination following major hepatectomy. HPB 21(11):1462-1469, 2019. e-Pub 2019.
- Wang T, Drill E, Vakiani E, Pak L, Boerner T, Askan G, Schvartzman JM, Simpson AL, Jarnagin WR, Sigel CS. Distinct histological features are associated with IDH1 mutation in intrahepatic cholangiocarcinoma. Hum Pathol 91:19-25, 2019. e-Pub 2019.
- Pak L, Mahvi DA, Urman RD, Gold JS, Whang EE. Discharge destination following pancreaticoduodenectomy: a NSQIP analysis of predictive factors and post-discharge outcome. American Journal of Surgery 218(2):342-348, 2019. e-Pub 2019.
- Fields AC, McCarty JC, Lu P, Vierra BM, Pak L, Irani J, Goldberg JE, Bleday R, Chan J, Melnitchouk N. Colon neuroendocrine tumors: a new lymph node staging classification. Ann Surg Oncol 26(7):2028-2036, 2019. e-Pub 2019.
- Pak LM, Yang T, Wang J. The safety and efficacy of gastrectomy for gastric cancer among octogenarians: a Western population-based study. J of Geriatr Oncol 10(4):598-603, 2019. e-Pub 2019.
- Pak L, Mahvi DA, Bose SK, Urman RD, Gold JS, Whang EE. Fast-tract pancreaticoduodenectomy: factors associated with early discharge. World Journal of Surgery 43(5):1332-1341, 2019. e-Pub 2019.
- Pak L, Gagniere J, Allen PJ, Balachandran VP, D'Angelica MI, DeMatteo RP, Jarnagin WR, Simpson AL. Utility of image guidance in the localization of disappearing colorectal liver metastases 23(4):760-767, 2019. e-Pub 2019.
- Pak LM, Yang T, Wang J. Further classification for node-positive gastric neuroendocrine neoplasms. J of Gastrointest Surg 23(4):720-729, 2019. e-Pub 2019.
- Fields AC, McCarty JC, Pak LM, Lu P, Irani J, Goldberg JE, Bleday R, Chan J, Melnitchouk N. New lymph node staging for rectal neuroendocrine tumors 119(1):156-162, 2019. e-Pub 2019.
- Sigel CS, Zhou Y, Basturk O, Drill E, Askan G, Pak LM, Vakiani E, Boerner T, Simpson AL, Jarnagin WR, Do RKG, Klimstra DS. Intrahepatic cholangiocarcinomas have histologically and immunophenotypically distinct small and large duct patterns. Am J Surg Pathol, 2018. e-Pub 2018.
- Aherne EA, Pak LM, Goldman DA, Gonen M, Jarnagin WR, Simpson AL, Do RKG. Intrahepatic cholangiocarcinoma: can imaging phenotypes predict survival and tumor genetics?. Abdom Radiol (NY) 43(10):2665-2672, 2018. e-Pub 2018.
- Changoor NR, Pak LM, Nguyen LL, Bleday R, Trinh QD, Koehlmoos T, Learn PA, Haider AH, Goldberg JE. The effect of an equal access military health system on racial disparities in colorectal cancer screening 124(18):3724-3732, 2018. e-Pub 2018.
- Pak LM, Gonen M, Seier K, Allen PJ, Balachandran VP, D'Angelica MI, Jarnagin WR, Kingham TP, Do RKG, Simpson AL. Can Physician Gestalt Predict Survival in Patients with Resectable Pancreatic Adenocarcinoma?. Abdom Radiol (NY) 43(8):2113-2118, 2018. e-Pub 2018.
- Pak L, Chaudhary M, Lange JK, Blucher JA, Barton LB, Sturgeon D, Koehlmoos T, Haider AH, Schoenfeld AJ. Does orthopedic outpatient care reduce emergency department utilization following total joint arthroplasty?. Clin Orthop Relat Res 476:1655-1662, 2018. e-Pub 2018.
- Pak L, Fogel HA, Chaudhary MA, Kwon NK, Barton LB, Koehlmoos T, Haider AH, Schoenfeld AJ. Outpatient spine clinic utilization is associated with reduced emergency department visits following spine surgery. Spine (Phila Pa 1976) 43(14):E836-E841, 2018. e-Pub 2018.
- Pak LM, Charkraborty J, Gonen M, Allen PJ, Balachandran VP, Chapman WC, D'Angelica MD, DeMatto RP, Do RKG, Kingham TP, Koerkamp BG, Lee SY, Massani M, Van De Stok EP, Jarnagin WR, Simpson AL. Quantitative imaging features of preoperative CT images predict postoperative hepatic insufficiency: a multi-institutional expansion cohort. J Am Coll Surg 226(5):835-843, 2018. e-Pub 2018.
- Pak L, Kemeny NE, Capanu M, Chou J, Boucher T, Cercek A, Balachandran VP, Kingham TP, Allen PJ, DeMatteo RP, Jarnagin WR, D'Angelica MI. Prospective phase II trial of combination hepatic artery infusion and systemic chemotherapy for unresectable colorectal liver metastases: long term results and curative potential. J Surg Onc 117(4):634-643, 2018. e-Pub 2018.
- Kingham TP, Pak LM, Simpson AL, Leung U, Doussot A, D'Angelica MI, DeMatteo RP, Allen PJ, Jarnagin WR. 3D image guidance identifies colorectal cancer liver metastases not seen on intraoperative ultrasound: results from a Phase II trial. HPB 20(3):260-267, 2018. e-Pub 2018.
- Pak L, Scattner MA, Balachandran VP, D'Angelica MI, DeMatteo RP, Kingham TP, Jarangin WR, Allen PJ. The clinical utility of immunoglobulin G4 in the evaluation of autoimmune pancreatitis and pancreatic adenocarcinoma. HPB 20(2):182-187, 2018. e-Pub 2018.
- Zheng J, Chakraborty J, Chapman WC, Gerst S, Pak L, Gonen M, Pak LM, Jarnagin WR, DeMatteo RP, Do RK, Simpson AL. Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma Using Quantitative CT Image Analysis. J Am Coll Surg 225(6):778-788, 2017. e-Pub 2017.
- Zheng J, Chakraborty J, Chapman WC, Gerst S, Gonen M, Pak LM, Jarnagin WR, DeMatteo RP, Do RK, Simpson AL, Allen PJ, Balachandran VP, D'Angelica MI, Kingham TP, Vachharajani N. Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma Using Quantitative CT Image Analysis. J Am Coll Surg, 2017. e-Pub 2017.
- Zheng J, Glezerman IG, Sadot E, McNeil A, Zamara C, Gonen M, Creasy J, Pak LM, Balachandran VP, D'Angelica MI, Allen PJ, DeMatteo RP, Kingham TP, Jarnagin WR, Jaimes EA. Hypophosphatemia Following Hepatectomy or Pancreatectomy: Role of the Phosphaturic Factor Nicotinamide Phosphoribosyltransferase. J Am Coll Surg 225(4):488-497, 2017. e-Pub 2017.
- Pak LM, D'Angelica MI, DeMatteo RP, Kingham TP, Balachandran VP, Jarnagin WR, Allen PJ. Natural history of patients followed radiographically with mucinous cysts of the pancreas. J Gastrointest Surg 21(10):1599-1605, 2017. e-Pub 2017.
- Pak L, Coit DG, Eaton AA, Allen PJ, D'Angelica MI, DeMatteo RP, Jarnagin WR, Strong VE, Kingham TP. Percutaneous peritoneal lavage for the rapid staging of gastric and pancreatic cancer. Ann Surg Oncol 24(5):1174-1179, 2017. e-Pub 2017.
- Pak LM, Dominguez-Rosado I, Gennarelli RL, Bach PB, Gonen M, D'Angelica MI, DeMatteo RP, Kingham TP, Brennan MF, Jarnagin WR, Allen PJ. The cost of postoperative pancreatic fistula vs. the cost of pasireotide: Results from a prospective randomized trial. Ann Surg 265(1):11-16, 2017. e-Pub 2017.
- Pak LM, Levi B, Oppenheimer AJ, Kasten SJ. Intralesional laser therapy for vascular malformations. Ann Plast Surg 73(5):547-551, 2014. e-Pub 2014.
- Parenteau CS, Ehrlich P, Pak LM, Su GL, Holcombe S, Wang SC. The quantification of liver anatomical changes and assessment of occupant liver injury patterns. Stapp Car Crash J 57:267-283, 2013. e-Pub 2013.
- Kothari V, Wei I, Shankar S, Kalyana- Sundaram S, Wang L, Pak LM, Vats P, Grasso CS, Robinson DR, Wu YM, Cao X, Simeone DM, Chinnaiyan AM, Kumar-Sinha C. Outlier kinase expression by RNA sequencing as targets for precision therapy. Cancer Discov 3(3):280-293, 2013. e-Pub 2013.
- Yang T, Fong ZV, Pak L, Wang SJ, Wei J, Wang J. A modified T-stage classification for gastric neuroendocrine tumors. Journals of Surgical Research 270:486-494.
Other Articles
- Li GZ, Tio MC, Pak LM, Krier J, Seifter JL, Tullius SG, Riella LV, Malek SK, Stergachis A Non-cirrhotic hyperammonemia after deceased donor kidney transplantation: a case report. Am J Transplant 19(11):3197-3201, 2019.
- Horvat N, Nikolovski I, Long N, Gerst S, Zheng J, Pak LM, Simpson A, Zheng J, Capanu M, Jarnagin WR, Mannelli L, Do RKG Imaging features of hepatocellular carcinoma compared to intrahepatic cholangiocarcinoma and combined tumor on MRI using liver imaging and data system (LI-RADS) version 2014. Abdom Radiol (NY) 43(1):169-178, 2018.
Selected Presentations & Talks
National Presentations
- 2022. How much pain will I have after surgery? A preoperative nomogram to predict pain following mastectomy. Poster. Society of Surgical Oncology Annual Meeting, US.
- 2020. Pathologic complete response in HER2-positive breast cancers with radiographically extensive disease. Poster. Society of Surgical Oncology Annual Meeting, US.
- 2020. Cancer awareness and stigma in rural Assam India: baseline survey of the Detect Early and Save Her/Him (DESH) program. Poster. Society of Surgical Oncology Annual Meeting, US.
- 2018. Further classification for node-positive gastric neuroendocrine neoplasms. Society for Surgery of the Alimentary Tract at Digestive Diseases Week, US.
- 2017. Quantitative imaging features of preoperative CT images predict postoperative hepatic insufficiency: a multi-institutional expansion cohort. Poster. San Diego, California, US.
- 2017. Mutational profiling of resected intrahepatic cholangiocarcinomas. Poster. 2017 American Society of Clinical Oncology (ASCO) Annual Meeting, US.
- 2017. Clinical utility of immunoglobulin-G4 in the diagnosis of autoimmune pancreatitis. Poster. Americas Hepato-Pancreato-Biliary Association 2017 Annual Meeting. Miami, Florida, US.
- 2016. Natural history of patients followed radiographically with mucinous cystic neoplasms of the pancreas. Poster. Society for Surgery of the Alimentary Tract at Digestive Diseases Week. San Diego, California, US.
- Prospective Phase II trial of combination hepatic artery and systemic chemotherapy for unresectable colorectal liver metastases: Long term results and curative potential. Poster. American College of Surgeons Clinical Congress, US.
International Presentations
- 2018. Utility of image guidance in the localization of disappearing colorectal liver metastases. Poster. 13th International Hepato-Pancreato-Biliary Association (IHPBA) World Congress, CH.
CV information above last modified May 23, 2025
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