Linghua Wang, M.D., Ph.D.

Peer-Reviewed Articles

1. Shui L, Liu Y, Lubo Julio IC, Clemenceau JR, Hoi XP, Dai Y, Lu W, Min J, Khan K, Roemer B, Jiang M, Waters RE, Colbert K, Maitra A, Wintermark M, Yuan Y, Chan KS, Hwang TH, Mansfield PF, Davis J, Solis Soto LM, Wang L, Li L, Li Z. UniST: A Unified Computational Framework for 3D Spatial Transcriptomics Reconstruction. bioRxiv, 2026. PMID: 41889901.
2. Li W, Mao L, Liu Y, Peng F, Sachs N, Wu W, Yiu SPT, Yan H, Schroeder A, Yu X, Jin K, Jiang S, Chen Z, Loth ML, Gomez L, Lubo I, Blank N, Samarah LZ, Basak A, Cho YW, Chen CY, Kim DM, Shalek AK, Solis Soto LM, Rabinowitz JD, Reilly MP, Qian X, Thaiss CA, Maegdefessel L, Wang L, Kadara H, Jiang S, Deng Y, Li M. Toward Computationally Complete Spatial Omics. bioRxiv, 2026. PMID: 41867863.
3. Jin K, Chen Z, Yu X, Yuan M, Schroeder A, Dumoulin B, Liu Y, Wang L, Park JH, Hwang TH, Susztak K, Ren Z, Zhang NR, Li M. Multiscale confidence quantification for virtual spatial transcriptomics with UTOPIA. bioRxiv, 2026. PMID: 41847009.
4. Chen Z, Ho IL, Liu J, Soeung M, Yen EY, Sainani S, Dyke CA, Shah R, Kwon HJ, Han G, Yan X, Zhang S, Srinivasan S, Rose JL, Citron F, Jiang S, Chang Q, Feng N, Genovese G, Gao S, Yao W, Wang L, Wang H, Ying H, Viale A, Draetta GF. GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma. Cancer Res 86(5):1132-1147, 2026. e-Pub 2026. PMID: 41329747.
5. Zhu B, Aminu M, Chen P, Li JR, Dong C, Li C, Tian Y, Lu SW, Chen H, Ma C, Hu X, Ye J, Liu AY, Huang B, Rojas FR, Roger PCE, Shi O, Nilsson MB, Poteete A, Khan KB, Lu W, Solis Soto LM, Fujimoto J, Haymaker C, Wistuba II, Wei Z, Wang L, Gibbons DL, Chen K, Reuben A, Schenkel JM, Heymach JV, Cheng C, Wu J, Zhang J. Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure. Adv Sci (Weinh) 13(17):e12597, 2026. e-Pub 2026. PMID: 41580978.
6. Jiang S, Coleman K, Chen Z, Jin K, Liu Y, Lee DH, Hwang TH, Xiao R, Jin J, Walsh CA, Qian X, Wang L, Li M. Reconstructing multi-scale tissue spatial architecture from single-cell RNA-seq with REMAP. bioRxiv, 2026. PMID: 41756915.
7. Minowa T, Keshari S, He S, Saha A, Shavkunov AS, Pineda JE, Yeo YY, Zhu B, Mohanty V, Jindal S, Chen K, Hu KH, Wang L, Nolan GP, Watowich SS, Gubin MM. Spatial immune hubs defined by conserved activated dendritic cells are remodeled by immunotherapy. bioRxiv, 2026. PMID: 41726948.
8. Peng, F, Sinjab, A, Dai, Y, Treekitkarnmongkol, W, Yang, S, Gomez Bolanos, L, Zhou, T, Chen, M, Serrano, A, Krishna, A, Karimi, N, Sharma, M, Basi, A, Pei, G, Liao, J, Liu, Y, Feng, J, Rahal, Z, Liu, Y, Jiang, J, Yu, K, Noun, T, Liu, Y, Khan, KB, Cho, KS, Chen, J, Solis Soto, LM, Mazzilli, SA, Dubinett, SM, Cascone, T, Spira, A, Swisher, SG, Jimbo, N, Hayashi, T, Kishikawa, S, Takamochi, K, Itoh, T, Yao, T, Suzuki, K, Kalhor, N, Wistuba, II, Li, M, Moghaddam, SM, Fujimoto, J, Burks, JK, Myers, JN, Akdemir, KC, Wang, L, Kadara, H. Multimodal spatial-omics reveal co-evolution of alveolar progenitors and proinflammatory niches in progression of lung precursor lesions. Cancer cell 44(2):321-339.e13, 2026. e-Pub 2026. PMID: 41202811.
9. Yao J, Shim JS, Wong K, Zhu J, Liu Y, Kang SW, Burt KBM, Choi JM, Lee C, Julio ICL, Soto LMS, Hernandez S, Colbert K, Lu W, Khan K, Mansfield PF, Jang HJ, Yue T, Li C, Zhu H, Wang L, Lee HS, Wang T. An Interpretable Multi-instance Learner Decodes Cellular Recruitment from Spatially Resolved Transcriptomics. bioRxiv, 2025. PMID: 41332779.
10. Fan, Y, Vykoukal, JV, Song, S, Pizzi, M, Zou, G, Yoshimura, K, Jin, J, Katayama, H, Calin, GA, Waters, R, Gan, Q, Wang, L, Hanash, S, Dhar, SS, Ajani, JA. Protocol for isolating patient-derived ascites cells and extracellular vesicles from gastric cancer peritoneal metastases. STAR Protocols 6(4), 2025. e-Pub 2025. PMID: 41105517.
11. Hou, J, Ju, CW, Egan, NA, Wei, Y, Wang, Y, Dang, M, Zhou, T, Shi, L, Zheng, N, Chen, S, Guerrero, AM, Liang, X, Wu, W, Akhtar, A, Dhiman, C, Roy Burman, D, Gerges, AE, Flores, MD, Li, H, Zhang, L, Kok, M, Mao, X, Wang, L, Feng, Q, Chen, Y, Lee, S, McGrail, DJ, Sahni, N, He, C, Jazaeri, AA, Peng, W. Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell-Induced Ferroptosis in Ovarian Cancer. Advanced Science 12(46), 2025. e-Pub 2025. PMID: 41042068.
12. Goswami, S, Gao, J, Basu, S, Shapiro, DD, Karam, JA, Tidwell, RS, Ahrar, K, Campbell, M, Shen, Y, Trevino, AE, Mayer, AT, Espejo, A, Seua, C, Macaluso, M, Chen, Y, Liu, W, He, Z, Yadav, SS, Wang, Y, Rao, P, Zhao, L, Zhang, J, Jindal, S, Tannir, NM, Futreal, A, Wang, L, Sharma, P. Immune checkpoint inhibitors plus debulking surgery for patients with metastatic renal cell carcinoma. Nature communications 16(1), 2025. e-Pub 2025. PMID: 39984485.
13. Stur, E, Peng, F, Teng, PN, Bayraktar, E, Hu, M, Corvigno, S, Brown, DJ, Lee, S, Moore, KN, Bateman, NW, Darcy, KM, Maxwell, GL, P. Conrads, T, Sahni, N, Vázquez-García, I, Shah, S, Celestino, J, D. Fleming, N, Navin, N, Wang, L, Sood, AK. The dynamic immune behavior of primary and metastatic ovarian carcinoma. npj Precision Oncology 9(1), 2025. e-Pub 2025. PMID: 40281242.
14. Soeung, M, Yan, X, Zanca, C, Qian, J, Karki, M, Duan, F, Khan, H, Zhang, L, Peng, D, Williams, M, He, R, Chen, Z, Perelli, L, Chen, J, Tidwell, R, Chauhan, PK, Le, C, Lam, TA, Bhattacharya, N, Shah, R, Ho, IL, Gay, J, Carrillo, CC, Feng, N, Le, K, Gao, G, Perry, TL, Mseeh, F, Jiang, Y, Xu, Q, Zacharias, NM, Sheth, RA, Bathala, TK, Rao, P, Daw Bitar, N, Tripathi, DN, Walker, CL, Mohammad, MM, Zhang, J, Han, G, Chu, Y, Wang, R, Dang, M, Dai, E, Peng, F, Liu, Y, Jadhav, A, Lang, W, Arrechedera, C, Clemente, LC, Parra Cuentas, ER, Lu, H, Haymaker, CL, Wistuba, II, Futreal, A, Viale, A, Soth, MJ, Jones, PH, Marszalek, JR, Heffernan, TP, Draetta, G, Tannir, NM, Gao, J, Wang, L, Genovese, G, Msaouel, P. Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma. Nature communications 16(1), 2025. e-Pub 2025. PMID: 41290625.
15. Yuan, M, Jin, K, Yan, H, Schroeder, A, Luo, C, Yao, S, Dumoulin, B, Levinsohn, J, Luo, T, Clemenceau, JR, Jang, I, Kim, M, Liu, Y, Deng, M, Furth, EE, Wilson, P, Nayak, A, Lubo Julio, IC, Solis Soto, LM, Wang, L, Park, JH, Susztak, K, Hwang, TH, Li, M. Smart spatial omics (S2-omics) optimizes region of interest selection to capture molecular heterogeneity in diverse tissues. Nature cell biology 27(12):2225-2238, 2025. e-Pub 2025. PMID: 41298871.
16. Montierth MD, Yan H, Xie L, Nemeth K, Pan X, Li R, Ercan C, Yang P, Sinjab A, Zhou T, Peng F, Singh M, Wang L, Kopetz S, Kadara H, Yuan Y, Calin GA, Wang W. Deconvolution of Sparse-count RNA Sequencing Data for Tumor Cells Using Embedded Negative Binomial Distributions. bioRxiv, 2025. PMID: 41394660.
17. Dai, Y, Kizhakeyil, A, Chihara, D, Li, X, Liu, Y, Sainz Zuniga, TP, Wilson, A, Henderson, J, Vibe, D, Petrosyants, A, Jacobson, CA, Sarachakov, A, Nomie, K, Kryukov, K, Bagaev, A, Chauhan, A, Westin, JR, Flowers, CR, Vega Vazquez, F, Wang, L, Green, M. Multi-modal spatial characterization of tumor immune microenvironments identifies targetable inflammatory niches in diffuse large B cell lymphoma. Nature Genetics 57(11):2715-2727, 2025. e-Pub 2025. PMID: 41120574.
18. Knisely, A, Dai, Y, Barlow, GL, Lee, S, Lawson, BC, Clark, HD, Fellman, B, Yuan, Y, Lu, W, Lubo Julio, IC, Lazcano, RN, Chelvanambi, M, Melendez, B, Singh, BB, Singh, B, Wani, K, Chen, J, Yeh, CC, Gao, J, Barnes, S, Shi, O, Khan, KB, Serrano, A, Gomez Bolanos, L, Scalise, CB, Cheung, SK, Dutta, P, Velichko, S, ElNaggar, AC, Liu, MC, Wilke, RN, How, JA, Ramondetta, LM, Boruta II, DM, Richardson, G, Shafer, A, Westin, SN, Sims, TT, Sood, AK, Ramirez, PT, Lazar, A, Soliman, PT, Lu, KH, Haymaker, CL, Solis Soto, LM, Wargo, J, Grisham, RN, Wucherpfennig, K, Wang, L, Jazaeri, AA. Surgical and Blood-Based Minimal Residual Disease in Patients with Ovarian Cancer after First-line Therapy. Clinical Cancer Research 31(19):4122-4135, 2025. e-Pub 2025. PMID: 40748258.
19. McAndrews, KM, Paradiso, F, Stalnecker, CA, Chellakkan Selvanesan, B, Thege, F, Peng, D, Moreno Diaz, BA, Sugimoto, H, Patel, SI, Mahadevan, KK, Kirtley, ML, Wills, D, Sockwell, AM, Fonseca, AF, Liu, Y, Rajapakshe, K, Yee, N, Tran, PT, Omar, HA, Tedeschi, A, Schischlik-Siegl, F, Boghossian, AS, Rees, MG, Ronan, MM, Roth, JA, Rudolph, D, Aichinger, M, Ebner, F, Artemov, AV, Lipp, J, Pisarsky, L, Herrmann, VL, Park, JE, Rippmann, JF, Schaaf, O, Chandler, V, Williams, M, Deckard, CE, Wang, L, Der, CJ, Vellano, CP, Guerrero, PA, Heffernan, TP, Kalluri, R, Maitra, A. An allele-agnostic mutant-KRAS inhibitor suppresses tumor maintenance signals and reprograms tumor immunity in pancreatic cancer. Science translational medicine 17(814), 2025. e-Pub 2025. PMID: 40901924.
20. Dai Y, Knisely A, Yano M, Dang M, Hinchcliff EM, Lee S, Welp A, Chelvanambi M, Lastrapes M, Liu H, Yuan Z, Wang C, Nie H, Jean S, Montaner LJ, Hou J, Patel A, Patel S, Fellman B, Yuan Y, Sun B, Pandurengan RK, Cuentas ERP, Celestino J, Liu Y, Liu J, Hillman RT, Westin SN, Sood AK, Soliman PT, Shafer A, Meyer LA, Gershenson DM, Vining D, Ganeshan D, Lu K, Wargo JA, Peng W, Zhang R, Wang L, Jazaeri AA. PPP2R1A mutations portend improved survival after cancer immunotherapy. Nature, 2025. e-Pub 2025. PMID: 40604275.
21. Song, S, Fan, Y, Zou, G, Huo, L, Kumar, J, Li, Y, Wang, R, Dai, E, Jin, J, Scott, AW, Shao, SH, Pizzi, M, Vykoukal, JV, Katayama, H, Hanash, S, Calin, GA, Zhang, X, Lee, MG, Wang, Z, Lo, Y, Gan, Q, Waters, R, Yin, F, Wang, L, Cheng, X, Ajani, JA, Dhar, SS. KAP1 promotes gastric adenocarcinoma progression by activating Hippo/YAP1 signaling via binding to HNRNPAB. Cancer Letters 621, 2025. e-Pub 2025. PMID: 40189014.
22. Huang J, Yuan C, Jiang J, Chen J, Badve SS, Gokmen-Polar Y, Segura RL, Yan X, Lazar A, Gao J, Yao B, Epstein M, Wang L, Hu J. Bridging cell morphological behaviors and molecular dynamics in multi-modal spatial omics with MorphLink. Nat Commun 16(1):5878, 2025. e-Pub 2025. PMID: 40595621.
23. Bernard V, Ku LT, Wang T, Acevedo-Diaz A, Rajapakshe KI, Jacobson G, Tovar D, Min J, Pei G, Tat C, Suresh A, Tzeng CD, Katz MH, Bhutani MS, Wang H, Wolff RA, Haymaker C, Ludmir EB, Huang H, Chen X, Li L, Koong AC, Wang L, Navin NE, Jiang D, Li Z, Maitra A, Koay EJ. A spatial atlas of chemoradiation therapy in pancreatic cancer identifies cellular and microenvironmental determinants of persister populations. bioRxiv, 2025. PMID: 40667350.
24. Pei, G, Min, J, Rajapakshe, K, Branchi, V, Liu, Y, Chellakkan Selvanesan, B, Thege, F, Sadeghian, D, Zhang, D, Cho, KS, Chu, Y, Dai, E, Han, G, Li, M, Yee, C, Takahashi, K, Garg, B, Tiriac, H, Bernard, V, Semaan, A, Grem, JL, Caffrey, TC, Burks, JK, Lowy, AM, Aguirre, AJ, Grandgenett, PM, Hollingsworth, MA, Guerrero, PA, Wang, L, Maitra, A. Spatial mapping of transcriptomic plasticity in metastatic pancreatic cancer. Nature 642(8066):212-221, 2025. e-Pub 2025. PMID: 40269162.
25. Zhao B, Cho CY, Ye L, Keal T, Mitchell T, Martin-Barrio I, Faraj CA, Unal M, Alsing J, Lawson NM, Kim ER, Chavez F, Rangel KM, Singh SK, McCarthy JH, Ashley DM, Yung WKA, Puduvalli V, Nir G, Weinberg JS, Wang L, Ligon KL, Genovese G, Loo PV, Futreal PA, Huse JT, Dixon JR, Lang FF, Akdemir KC. Oncogenic drivers shape the tumor microenvironment in human gliomas. bioRxiv, 2025. PMID: 40475555.
26. Liu, Y, Sinjab, A, Min, J, Han, G, Paradiso, F, Zhang, Y, Wang, R, Pei, G, Dai, Y, Liu, Y, Cho, KS, Dai, E, Basi, A, Burks, JK, Rajapakshe, K, Chu, Y, Jiang, J, Zhang, D, Yan, X, Guerrero, PA, Serrano, A, Li, M, Hwang, TH, Futreal, A, Ajani, JA, Solis-Soto, L, Jazaeri, AA, Kadara, HN, Maitra, A, Wang, L. Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics. Cancer cell 43(5):905-924.e6, 2025. e-Pub 2025. PMID: 40154487.
27. Zhao Z, Hu B, Deng Y, Soeung M, Yao J, Bei L, Zhang Y, Gong P, Huang LA, Jiang Z, Gao J, Peng S, Nguyen TK, Karki M, Lim B, Yee C, Burks JK, Zhang Q, Ma L, Gao J, Tannir NM, Han L, Yu D, Wang L, Curran MA, Gubbiotti MA, Genovese G, Gan B, Li W, Msaouel P, Yang L, Lin C. Sickle cell disease induces chromatin introversion and ferroptosis in CD8(+) T cells to suppress anti-tumor immunity. Immunity, 2025. e-Pub 2025. PMID: 40359940.
28. Zhu B, Chen P, Aminu M, Li JR, Fujimoto J, Tian Y, Hong L, Chen H, Hu X, Li C, Vokes N, Moreira AL, Gibbons DL, Solis Soto LM, Parra Cuentas ER, Shi O, Diao S, Ye J, Rojas FR, Vilar E, Maitra A, Chen K, Navin N, Nilsson M, Huang B, Heeke S, Zhang J, Haymaker CL, Velcheti V, Sterman DH, Kochat V, Padron WI, Alexandrov LB, Wei Z, Le X, Wang L, Fukuoka J, Lee JJ, Wistuba II, Pass HI, Davis M, Hanash S, Cheng C, Dubinett S, Spira A, Rai K, Lippman SM, Futreal PA, Heymach JV, Reuben A, Wu J, Zhang J. Spatial and multiomics analysis of human and mouse lung adenocarcinoma precursors reveals TIM-3 as a putative target for precancer interception. Cancer Cell, 2025. e-Pub 2025. PMID: 40345189.
29. Perelli, L, Zhang, L, Mangiameli, S, Giannese, F, Mahadevan, KK, Peng, F, Citron, F, Khan, H, Le, C, Gurreri, E, Carbone, F, Russell, AJ, Soeung, M, Lam, TA, Lundgren, S, Marisetty, S, Zhu, C, Catania, D, Mohamed, AM, Feng, N, Augustine, JJ, Sgambato, A, Tortora, G, Draetta, G, Tonon, G, Futreal, A, Giuliani, V, Carugo, A, Viale, A, Kim, M, Heffernan, TP, Wang, L, Kalluri, R, Cittaro, D, Chen, F, Genovese, G. Evolutionary fingerprints of epithelial-to-mesenchymal transition. Nature 640(8060):1083-1092, 2025. e-Pub 2025. PMID: 40044861.
30. Yoshimura, K, Zou, G, Fan, Y, Yamashita, K, Wang, L, Wu, J, Wang, R, Shao, SH, Scott, AW, Jin, J, Pizzi, M, Yao, X, Brown, CA, Wang, L, Gan, Q, Waters, R, Yin, F, Song, S, Dhar, SS, Ajani, JA. HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer. Cancer Letters 610, 2025. e-Pub 2025. PMID: 39603381.
31. Gubbiotti MA, McCutcheon IE, Rao P, Genovese G, Wang L, Tarasov A, Putintsev V, Berlinski A, Stupichev D, Kriukov K, Davitavyan S, Salem B, Sarachakov A, Lebedev D, Hensley M, Bagaev A, Paradiso F, Kushnarev V, Khegai G, Tannir NM, Msaouel P. A novel case of glial transdifferentiation in renal medullary carcinoma brain metastasis. Acta Neuropathol Commun 13(1):12, 2025. e-Pub 2025. PMID: 39833894.
32. Fan Y, Song S, Pizzi MP, Zou G, Vykoukal JV, Yoshimura K, Jin J, Calin GA, Waters RE, Gan Q, Wang L, Hanash S, Dhar SS, Ajani JA. Exosomal Galectin-3 promotes peritoneal metastases in gastric adenocarcinoma via microenvironment alterations. iScience 28(1):111564, 2025. e-Pub 2025. PMID: 39811647.
33. Coleman K, Schroeder A, Loth M, Zhang D, Park JH, Sung JY, Blank N, Cowan AJ, Qian X, Chen J, Jiang J, Yan H, Samarah LZ, Clemenceau JR, Jang I, Kim M, Barnfather I, Rabinowitz JD, Deng Y, Lee EB, Lazar A, Gao J, Furth EE, Hwang TH, Wang L, Thaiss CA, Hu J, Li M. Resolving tissue complexity by multimodal spatial omics modeling with MISO. Nat Methods, 2025. e-Pub 2025. PMID: 39815104.
34. Msaouel P, Yu K, Yuan Y, Chen J, Yan X, Karki M, Duan F, Sheth RA, Rao P, Sircar K, Shah AY, Zurita AJ, Genovese G, Li M, Yeh CC, Dang M, Han G, Chu Y, Hallin M, Olson P, Yang R, Slavin D, Der-Torossian H, Chin CD, Tannir NM, Wang L, Gao J. Sitravatinib in combination with nivolumab plus ipilimumab in patients with advanced clear cell renal cell carcinoma: a phase 1 trial. Nat Commun 16(1):578, 2025. e-Pub 2025. PMID: 39794332.
35. Citron F, Ho IL, Balestrieri C, Liu Z, Yen EN, Cecchetto L, Perelli L, Zhang L, Castillo Montanez LA, Blazanin N, Dyke CA, Shah R, Attanasio S, Srinivasan S, Chen KC, Chen Z, Scognamiglio I, Pham N, Khan H, Jiang S, Pan J, Vanderkruk B, Leung C, Mattohti M, Rai K, Chu Y, Wang L, Gao S, Deem AK, Carugo A, Wang H, Yao W, Tonon G, Xiong Y, Lorenzi PL, Bonini C, Zal A, Hoffman B, Giuliani V, Heffernan T, Jeter CR, Lissanu Y, Genovese G, Di Pilato M, Viale A, Draetta GF. WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer. bioRxiv, 2025. PMID: 39484624.
36. Rahal, Z, Liu, Y, Peng, F, Yang, S, Jamal, M, Sharma, M, Moreno, H, Damania, A, Wong, M, Ross, MC, Sinjab, A, Zhou, T, Chen, M, Reischle, IT, Feng, J, Chukwuocha, C, Tang, EL, Abaya, C, Lim, JK, Leung, CH, Lin, HY, Deboever, N, Lee, JJ, Sepesi, B, Gibbons, DL, Wargo, J, Fujimoto, J, Wang, L, Petrosino, JF, Ajami, NJ, Jenq, RR, Moghaddam, SM, Cascone, T, Hoffman, KL, Kadara, HN. Inflammation Mediated by Gut Microbiome Alterations Promotes Lung Cancer Development and an Immunosuppressed Tumor Microenvironment. Cancer Immunology Research 12(12):1736-1752, 2024. e-Pub 2024. PMID: 39269772.
37. Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi MP, Lazcano R, Yamashita K, Xu Z, Pei G, Cho KS, Chu Y, Sinjab A, Peng F, Yan X, Han G, Wang R, Dai E, Dai Y, Czerniak BA, Futreal A, Maitra A, Lazar A, Kadara H, Jazaeri AA, Cheng X, Ajani J, Gao J, Hu J, Wang L. METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics. Nat Commun 15(1):7312, 2024. e-Pub 2024. PMID: 39181865.
38. How JA, Dang M, Lee S, Fellman B, Westin SN, Sood AK, Fleming ND, Shafer A, Yuan Y, Liu J, Zhao L, Celestino J, Hajek R, Morgan MB, Parra ER, Laberiano Fernandez CD, Arrechedera CA, Solis Soto LM, Schmeler KM, Nick A, Lu KH, Coleman R, Wang L, Jazaeri AA. Pembrolizumab plus chemotherapy in frontline treatment of advanced ovarian cancer: Clinical and translational results from a phase 2 trial. Med, 2024. e-Pub 2024. PMID: 39151421.
39. Gupta P, Dang M, Oberai S, Migliozzi S, Trivedi R, Kumar G, Peshoff M, Milam N, Ahmed A, Bojja K, Tran TM, Gumin J, Kamiya-Matsuoka C, Huse J, Cox K, Li J, Shehwana H, Sheth SA, Saxon R, Baohua S, Parker-Kerrigan B, Maheshwari A, Parra Cuentas ER, Navin NE, Heimberger AB, Lang FF, Iavarone A, Clise-Dwyer K, Wang L, Bhat KP. Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas. Neuro Oncol, 2024. e-Pub 2024. PMID: 39126294.
40. Cheng X, Dai E, Wu J, Flores NM, Chu Y, Wang R, Dang M, Xu Z, Han G, Liu Y, Chatterjee D, Hu C, Ying J, Du Y, Yang L, Guan X, Mo S, Cao X, Pei G, Jiang J, Lu X, Benitez AM, Waters RE, Pizzi MP, Shanbhag N, Fan Y, Peng F, Hanash SM, Calin G, Futreal A, Song S, Yee C, Mazur PK, Qin JJ, Ajani JA, Wang L. Atlas of metastatic gastric cancer links ferroptosis to disease progression and immunotherapy response. Gastroenterology, 2024. e-Pub 2024. PMID: 39097198.
41. Park J, Wu J, Szkop KJ, Jeong J, Jovanovic P, Husmann D, Flores NM, Francis JW, Chen YC, Benitez AM, Zahn E, Song S, Ajani JA, Wang L, Singh K, Larsson O, Garcia BA, Topisirovic I, Gozani O, Mazur PK. SMYD5 methylation of rpL40 links ribosomal output to gastric cancer. Nature 632(8025):656-663, 2024. e-Pub 2024. PMID: 39048817.
42. Siddiqui BA, Palaskas NL, Basu S, Dai Y, He Z, Yadav SS, Allison JP, Sheth RA, Tummala S, Buja M, Bhattacharjee MB, Iliescu C, Rawther-Karedath A, Deswal A, Wang L, Sharma P, Subudhi SK. Molecular pathways and cellular subsets associated with adverse clinical outcomes in overlapping immune-related myocarditis and myositis. Cancer Immunol Res, 2024. e-Pub 2024. PMID: 38768394.
43. Peshoff MM, Gupta P, Oberai S, Trivedi R, Katayama H, Chakrapani P, Dang M, Migliozzi S, Gumin J, Kadri DB, Lin JK, Milam NK, Maynard ME, Vaillant BD, Parker-Kerrigan B, Lang FF, Huse JT, Iavarone A, Wang L, Clise-Dwyer K, Bhat KP. Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma. Neuro Oncol 26(5):826-839, 2024. e-Pub 2024. PMID: 38237157.
44. Yamashita K, Sewastjanow-Silva M, Yoshimura K, Rogers JE, Rosa Vicentini E, Pool Pizzi M, Fan Y, Zou G, Li JJ, Blum Murphy M, Gan Q, Waters RE, Wang L, Ajani JA. SMARCA4 Mutations in Gastroesophageal Adenocarcinoma: An Observational Study via a Next-Generation Sequencing Panel. Cancers (Basel) 16(7), 2024. e-Pub 2024. PMID: 38610978.
45. Ho IL, Li CY, Wang F, Zhao L, Liu J, Yen EY, Dyke CA, Shah R, Liu Z, Cetin AO, Chu Y, Citron F, Attanasio S, Corti D, Darbaniyan F, Del Poggetto E, Loponte S, Liu J, Soeung M, Chen Z, Jiang S, Jiang H, Inoue A, Gao S, Deem A, Feng N, Ying H, Kim M, Giuliani V, Genovese G, Zhang J, Futreal A, Maitra A, Heffernan T, Wang L, Do KA, Gargiulo G, Draetta G, Carugo A, Lin R, Viale A. Clonal dominance defines metastatic dissemination in pancreatic cancer. Sci Adv 10(11):eadd9342, 2024. e-Pub 2024. PMID: 38478609.
46. Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, Pei G, Hu J, Abaya C, Gomez-Bolanos LI, Peng F, Chen M, Parra ER, Cascone T, Sepesi B, Moghaddam SJ, Scheet P, Negrao MV, Heymach JV, Li M, Dubinett SM, Stevenson CS, Spira AE, Fujimoto J, Solis LM, Wistuba II, Chen J, Wang L, Kadara H. An atlas of epithelial cell states and plasticity in lung adenocarcinoma. Nature 627(8004):656-663, 2024. e-Pub 2024. PMID: 38418883.
47. Dacic, S, Cao, X, Bota Rabassedas, MN, Sanchez Espiridion, B, Berezowska, S, Han, Y, Chung, JH, Beasley, MB, Dongmei, L, Hwang, D, Mino-Kenudson, M, Minami, Y, Papotti, M, Rekhtman, N, Roden, AC, Thunnissen, E, Tsao, MS, Yatabe, Y, Yoshida, A, Wang, L, Hartman, DJ, Jerome, JA, Kadara, HN, Chou, TY, Wistuba, II. Genomic Staging of Multifocal Lung Squamous Cell Carcinomas Is Independent of the Comprehensive Morphologic Assessment. Journal of Thoracic Oncology 19(2):273-284, 2024. e-Pub 2024. PMID: 37717856.
48. Zhang D, Schroeder A, Yan H, Yang H, Hu J, Lee MYY, Cho KS, Susztak K, Xu GX, Feldman MD, Lee EB, Furth EE, Wang L, Li M. Inferring super-resolution tissue architecture by integrating spatial transcriptomics with histology. Nat Biotechnol 42(9):1372-1377, 2024. e-Pub 2024. PMID: 38168986.
49. Perelli L, Zhang L, Mangiameli S, Russell AJC, Giannese F, Peng F, Carbone F, Le C, Khan H, Citron F, Soeung M, Lam TNA, Lundgren S, Zhu C, Catania D, Feng N, Gurreri E, Sgambato A, Tortora G, Draetta GF, Tonon G, Futreal A, Giuliani V, Carugo A, Viale A, Heffernan TP, Wang L, Cittaro D, Chen F, Genovese G. Evolutionary fingerprints of EMT in pancreatic cancers. bioRxiv, 2023. PMID: 37786705.
50. Stephen, B, Hajjar, J, Sarda, S, Duose, D, Conroy, J, Morrison, C, Alshawa, A, Xu, M, Zarifa, A, Patel, SP, Yuan, Y, Kwiatkowski, E, Wang, L, Rodon Ahnert, J, Fu, S, Meric-Bernstam, F, Lowman, G, Looney, TJ, Naing, A. T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy. Journal for immunotherapy of cancer 11(8), 2023. e-Pub 2023. PMID: 37604642.
51. Strati, P, Li, X, Deng, Q, Marques-Piubelli, ML, Henderson, J, Watson, G, Deaton, FL, Cain, JT, Yang, H, Ravanmehr, V, Fayad, LE, Iyer, SP, Nastoupil, L, Hagemeister, FB, Parra, ER, Saini, N, Takahashi, K, Fowler, N, Westin, JR, Steiner, RE, Nair, R, Flowers, CR, Wang, L, Ahmed, S, Al-Atrash, G, Vega, F, Neelapu, SS, Green, M. Prolonged cytopenia following CD19 CAR T cell therapy is linked with bone marrow infiltration of clonally expanded IFNγ-expressing CD8 T cells. Cell Reports Medicine 4(8):101158, 2023. e-Pub 2023. PMID: 37586321.
52. Wang R, Song S, Qin J, Yoshimura K, Peng F, Chu Y, Li Y, Fan Y, Jin J, Dang M, Dai E, Pei G, Han G, Hao D, Li Y, Chatterjee D, Harada K, Pizzi MP, Scott AW, Tatlonghari G, Yan X, Xu Z, Hu C, Mo S, Shanbhag N, Lu Y, Sewastjanow-Silva M, Fouad Abdelhakeem AA, Peng G, Hanash SM, Calin GA, Yee C, Mazur P, Marsden AN, Futreal A, Wang Z, Cheng X, Ajani JA, Wang L. Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression. Cancer Cell 41(8):1407-1426, 2023. e-Pub 2023. PMID: 37419119.
53. Fan, H, Wang, F, Zeng, A, Murison, A, Tomczak, K, Hao, D, Jelloul, FZ, Wang, B, Barrodia, P, Liang, S, Chen, K, Wang, L, Zhao, Z, Rai, K, Jain, A, Dick, JE, Daver, N, Futreal, A, Abbas, HA. Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance. Communications Biology 6(1), 2023. e-Pub 2023. PMID: 37479893.
54. Li, C, Zhang, B, Schaafsma, E, Reuben, A, Wang, L, Turk, MJ, Zhang, J, Cheng, C. TimiGP: Inferring cell-cell interactions and prognostic associations in the tumor immune microenvironment through gene pairs. Cell Reports Medicine 4(7), 2023. e-Pub 2023. PMID: 37467716.
55. Qian Y, Galan-Cobo A, Guijarro I, Dang M, Molkentine D, Poteete A, Zhang F, Wang Q, Wang J, Parra E, Panda A, Fang J, Skoulidis F, Wistuba II, Verma S, Merghoub T, Wolchok JD, Wong KK, DeBerardinis RJ, Minna JD, Vokes NI, Meador CB, Gainor JF, Wang L, Reuben A, Heymach JV. MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma. Cancer Cell 41(7):1363-1380, 2023. e-Pub 2023. PMID: 37327788.
56. Perelli L, Carbone F, Zhang L, Huang JK, Le C, Khan H, Citron F, Del Poggetto E, Gutschner T, Tomihara H, Soeung M, Minelli R, Srinivasan S, Peoples M, Lam TNA, Lundgren S, Xia R, Zhu C, Mohamed AMT, Zhang J, Sircar K, Sgambato A, Gao J, Jonasch E, Draetta GF, Futreal A, Bakouny Z, Van Allen EM, Choueiri T, Signoretti S, Msaouel P, Litchfield K, Turajlic S, Wang L, Chen YB, Di Natale RG, Hakimi AA, Giuliani V, Heffernan TP, Viale A, Bristow CA, Tannir NM, Carugo A, Genovese G. Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer. Nature Cancer 4(7):984-1000, 2023. e-Pub 2023. PMID: 37365326.
57. Dang M, Wang R, Lee HC, Patel KK, Becnel MR, Han G, Thomas SK, Hao D, Chu Y, Weber DM, Lin P, Lutter-Berka Z, Berrios Nolasco DA, Huang M, Bansal H, Song X, Zhang J, Futreal A, Moreno Rueda LY, Symer DE, Green MR, Rojas Hernandez CM, Kroll M, Afshar-Khargan V, Ndacayisaba LJ, Kuhn P, Neelapu SS, Orlowski RZ, Wang L, Manasanch EE. Single cell clonotypic and transcriptional evolution of multiple myeloma precursor disease. Cancer Cell 41(6):1032-1047.e4, 2023. e-Pub 2023. PMID: 37311413.
58. Chu Y, Dai E, Li Y, Han G, Pei G, Ingram DR, Thakkar K, Qin JJ, Dang M, Le X, Hu C, Deng Q, Sinjab A, Gupta P, Wang R, Hao D, Peng F, Yan X, Liu Y, Song S, Zhang S, Heymach JV, Reuben A, Elamin YY, Pizzi MP, Lu Y, Lazcano R, Hu J, Li M, Curran M, Futreal A, Maitra A, Jazaeri AA, Ajani JA, Swanton C, Cheng XD, Abbas HA, Gillison M, Bhat K, Lazar AJ, Green M, Litchfield K, Kadara H, Yee C, Wang L. Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance. Nat Med 29(6):1550-1562, 2023. e-Pub 2023. PMID: 37248301.
59. Zhao S, Wang R, Song S, Hao D, Han G, Song X, Zhang J, Pizzi MP, Shanbhag N, Futreal A, Badgwell B, Harada K, Calin G, Vykoukal J, Yu CY, Katayama H, Hanash SM, Wang L, Ajani JA. Proteogenomic landscape of gastric adenocarcinoma peritoneal metastases. iScience 26(6):106913, 2023. e-Pub 2023. PMID: 37305699.
60. Hu J, Coleman K, Zhang D, Lee EB, Kadara H, Wang L, Li M. Deciphering tumor ecosystems at super resolution from spatial transcriptomics with TESLA. Cell Syst 14(5):404-417.e4, 2023. e-Pub 2023. PMID: 37164011.
61. Jin J, Huo L, Fan Y, Wang R, Scott AW, Pizzi MP, Yao X, Shao S, Ma L, Da Silva MS, Yamashita K, Yoshimura K, Zhang B, Wu J, Wang L, Song S, Ajani JA. A new intronic quantitative PCR method led to the discovery of transformation from human ascites to murine malignancy in a mouse model. Front Oncol 13:1062424, 2023. e-Pub 2023. PMID: 36865791.
62. Fan, Y, Song, S, Li, Y, Dhar, SS, Jin, J, Yoshimura, K, Yao, X, Wang, R, Scott, AW, Pizzi, MP, Wu, J, Ma, L, Calin, GA, Hanash, S, Wang, L, Curran, M, Ajani, JA. Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T-cell Immunity in Gastric Cancer Peritoneal Metastases. Cancer Research 83(22):3726-3738, 2023. e-Pub 2023. PMID: 37738407.
63. Hao D, Han G, Sinjab A, Gomez-Bolanos LI, Lazcano R, Serrano A, Hernandez SD, Dai E, Cao X, Hu J, Dang M, Wang R, Chu Y, Song X, Zhang J, Parra ER, Wargo JA, Swisher SG, Cascone T, Sepesi B, Futreal AP, Li M, Dubinett SM, Fujimoto J, Solis Soto LM, Wistuba II, Stevenson CS, Spira A, Shalapour S, Kadara H, Wang L. The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma. Cancer Discov 12(11):2626-2645, 2022. e-Pub 2022. PMID: 36098652.
64. Jiang VC, Hao D, Jain P, Li Y, Cai Q, Yao Y, Nie L, Liu Y, Jin J, Wang W, Lee HH, Che Y, Dai E, Han G, Wang R, Rai K, Futreal A, Flowers C, Wang L, Wang M. TIGIT is the central player in T-cell suppression associated with CAR T-cell relapse in mantle cell lymphoma. Mol Cancer 21(1):185, 2022. e-Pub 2022. PMID: 36163179.
65. Han G, Deng Q, Marques-Piubelli ML, Dai E, Dang M, Ma MCJ, Li X, Yang H, Henderson J, Kudryashova O, Meerson M, Isaev S, Kotlov N, Nomie KJ, Bagaev A, Parra ER, Solis Soto LM, Parmar S, Hagemeister FB, Ahmed S, Iyer SP, Samaniego F, Steiner R, Fayad L, Lee H, Fowler NH, Flowers CR, Strati P, Westin JR, Neelapu SS, Nastoupil LJ, Vega F, Wang L, Green MR. Follicular lymphoma microenvironment characteristics associated with tumor cell mutations and MHC class II expression. Blood Cancer Discov 3(5):428-443, 2022. e-Pub 2022. PMID: 35687817.
66. Cherng HJ, Sun R, Sugg B, Irwin R, Yang H, Le CC, Deng Q, Fayad L, Fowler NH, Parmar S, Steiner R, Hagemeister F, Nair R, Lee HJ, Rodriguez M, Samaniego F, Iyer SP, Flowers CR, Wang L, Nastoupil LJ, Neelapu SS, Ahmed S, Strati P, Green MR, Westin J. Risk assessment with low-pass whole-genome sequencing of cell-free DNA before CD19 CAR T-cell therapy for large B-cell lymphoma. Blood 140(5):504-515, 2022. e-Pub 2022. PMID: 35512184.
67. Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, Wang S, Huo L, Wang Y, Wang R, Pool Pizzi M, Ma L, Shao S, Sewastjanow-Silva M, Waters R, Chatterjee D, Liu B, Shanbhag N, Peng G, Calin GA, Mazur PK, Hanash SM, Ishizawa J, Hirata Y, Nagano O, Wang Z, Wang L, Xian W, McKeon F, Ajani JA, Song S. Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment. Gut 72(4):624-637, 2022. e-Pub 2022. PMID: 36002248.
68. Vellano CP, White MG, Andrews MC, Chelvanambi M, Witt RG, Daniele JR, Titus M, McQuade JL, Conforti F, Burton EM, Lastrapes MJ, Ologun G, Cogdill AP, Morad G, Prieto P, Lazar AJ, Chu Y, Han G, Khan MAW, Helmink B, Davies MA, Amaria RN, Kovacs JJ, Woodman SE, Patel S, Hwu P, Peoples M, Lee JE, Cooper ZA, Zhu H, Gao G, Banerjee H, Lau M, Gershenwald JE, Lucci A, Keung EZ, Ross MI, Pala L, Pagan E, Segura RL, Liu Q, Borthwick MS, Lau E, Yates MS, Westin SN, Wani K, Tetzlaff MT, Haydu LE, Mahendra M, Ma X, Logothetis C, Kulstad Z, Johnson S, Hudgens CW, Feng N, Federico L, Long GV, Futreal PA, Arur S, Tawbi HA, Moran AE, Wang L, Heffernan TP, Marszalek JR, Wargo JA. Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy. Nature 606(7915):797-803, 2022. e-Pub 2022. PMID: 35705814.
69. Kim ST, Chu Y, Misoi M, Suarez-Almazor ME, Tayar JH, Lu H, Buni M, Kramer J, Rodriguez E, Hussain Z, Neelapu SS, Wang J, Shah AY, Tannir NM, Campbell MT, Gibbons DL, Cascone T, Lu C, Blumenschein GR, Altan M, Lim B, Valero V, Loghin ME, Tu J, Westin SN, Naing A, Garcia-Manero G, Abdel-Wahab N, Tawbi HA, Hwu P, Oliva ICG, Davies MA, Patel SP, Zou J, Futreal A, Diab A, Wang L, Nurieva R. Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy. Nature communications 13(1):1970, 2022. e-Pub 2022. PMID: 35413951.
70. Alhalabi O, Chen J, Zhang Y, Lu Y, Wang Q, Ramachandran S, Tidwell RS, Han G, Yan X, Meng J, Wang R, Hoang AG, Wang WL, Song J, Lopez L, Andreev-Drakhlin A, Siefker-Radtke A, Zhang X, Benedict WF, Shah AY, Wang J, Msaouel P, Zhang M, Guo CC, Czerniak B, Behrens C, Soto L, Papadimitrakopoulou V, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee J, Roth J, Swisher S, Wistuba I, Heymach J, Wang J, Campbell MT, Efstathiou E, Titus M, Logothetis CJ, Ho TH, Zhang J, Wang L, Gao J. MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers. Nature communications 13(1):1797, 2022. e-Pub 2022. PMID: 35379845.
71. Dong X, Song S, Li Y, Fan Y, Wang L, Wang R, Huo L, Scott A, Xu Y, Pizzi MP, Ma L, Wang Y, Jin J, Zhao W, Yao X, Johnson RL, Wang L, Wang Z, Peng G, Ajani JA. Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma-rationale for targeting ARID1A deficiency. Gut 71(3):467-478, 2022. e-Pub 2022. PMID: 33785559.
72. Wang, L, Jain, P, Zhao, S, Lee, HJ, Nastoupil, L, Fayad, LE, Ok, CY, Kanagal Shamanna, R, Hill, H, Yao, Y, Hagemeister, FB, Westin, JR, Fowler, N, Samaniego, F, Steiner, RE, Nair, R, Iyer, SP, Navsaria, L, Badillo, M, Feng, L, Huang, X, Nogueras Gonzalez, G, Xu, G, Wagner-Bartak, N, Thirumurthi, S, Santos, DA, Tang, G, Lin, P, Wang, S, Jorgensen, JL, Yin, CC, Li, S, Patel, KP, Vega Vazquez, F, Medeiros, LJ, Flowers, CR, Wang, L. Ibrutinib–rituximab followed by R-HCVAD as frontline treatment for young patients (≤65 years) with mantle cell lymphoma (WINDOW-1). Lancet Oncol 23(3):406-415, 2022. e-Pub 2022. PMID: 35074072.
73. Fedoriw A, Shi L, O'Brien S, Smitheman KN, Wang Y, Hou J, Sherk C, Rajapurkar S, Laraio J, Williams LJ, Xu C, Han G, Feng Q, Bedford MT, Wang L, Barbash O, Kruger RG, Hwu P, Mohammad HP, Peng W. Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response. Cancer Immunology Research 10(4):420-436, 2022. e-Pub 2022. PMID: 35181787.
74. Jain P, Zhao S, Lee HJ, Hill HA, Ok CY, Kanagal-Shamanna R, Hagemeister FB, Fowler N, Fayad L, Yao Y, Liu Y, Moghrabi OB, Navsaria L, Feng L, Nogueras Gonzalez GM, Xu G, Thirumurthi S, Santos D, Iliescu C, Tang G, Medeiros LJ, Vega F, Avellaneda M, Badillo M, Flowers CR, Wang L, Wang ML. Ibrutinib With Rituximab in First-Line Treatment of Older Patients With Mantle Cell Lymphoma. Journal of Clinical Oncology 40(2):202-212, 2022. e-Pub 2022. PMID: 34797699.
75. Jimenez JE, Dai D, Xu G, Zhao R, Li T, Pan T, Wang L, Lin Y, Wang Z, Jaffray D, Hazle JD, Macapinlac HA, Wu J, Lu Y. Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma. Clinical nuclear medicine 47(3):209-218, 2022. e-Pub 2022. PMID: 35020640.
76. Spencer CN, McQuade JL, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X, White MG, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, Andrews MC, Rodrigues RR, Morgun A, Kim YS, Roszik J, Hoffman KL, Zheng J, Zhou Y, Medik YB, Kahn LM, Johnson S, Hudgens CW, Wani K, Gaudreau PO, Harris AL, Jamal MA, Baruch EN, Perez-Guijarro E, Day CP, Merlino G, Pazdrak B, Lochmann BS, Szczepaniak-Sloane RA, Arora R, Anderson J, Zobniw CM, Posada E, Sirmans E, Simon J, Haydu LE, Burton EM, Wang L, Dang M, Clise-Dwyer K, Schneider S, Chapman T, Anang NAS, Duncan S, Toker J, Malke JC, Glitza IC, Amaria RN, Tawbi HA, Diab A, Wong MK, Patel SP, Woodman SE, Davies MA, Ross MI, Gershenwald JE, Lee JE, Hwu P, Jensen V, Samuels Y, Straussman R, Ajami NJ, Nelson KC, Nezi L, Petrosino JF, Futreal PA, Lazar AJ, Hu J, Jenq RR, Tetzlaff MT, Yan Y, Garrett WS, Huttenhower C, Sharma P, Watowich SS, Allison JP, Cohen L, Trinchieri G, Daniel CR, Wargo JA. Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response. Science 374(6575):1632-1640, 2021. e-Pub 2021. PMID: 34941392.
77. Hao D, He S, Harada K, Pizzi MP, Lu Y, Guan P, Chen L, Wang R, Zhang S, Sewastjanow-Silva M, Abdelhakeem A, Shanbhag N, Bhutani M, Han G, Lee JH, Zhao S, Weston B, Blum Murphy M, Waters R, Estrella JS, Roy-Chowdhuri S, Gan Q, Lee JS, Peng G, Hanash SM, Calin GA, Song X, Zhang J, Song S, Wang L, Ajani JA. Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma. Gut 70(11):2055-2065, 2021. e-Pub 2021. PMID: 33334899.
78. Alhalabi O, Zhu Y, Hamza A, Qiao W, Lin Y, Wang RM, Shah AY, Campbell MT, Holla V, Kamat A, Wang WL, Wang J, Chen J, Meng J, Zhang M, Bondaruk J, Titus M, Genovese G, Czerniak BA, Shaw KR, Meric-Bernstam F, Guo CC, Logothetis CJ, Siefker-Radtke A, Msaouel P, Wang L, Liu J, Gao J. Integrative Clinical and Genomic Characterization of MTAP-deficient Metastatic Urothelial Cancer. Eur Urol Oncol 6(2):228-232, 2021. e-Pub 2021. PMID: 34789422.
79. Szczepaniak Sloane, RA, White, MG, Witt, RG, Banerjee, A, Davies, MA, Han, G, Burton, EM, Ajami, NJ, Simon, JM, Bernatchez, C, Haydu, LE, Tawbi, H, Gershenwald, JE, Keung, EZ, Ross, MI, McQuade, JL, Amaria, RN, Wani, K, Lazar, A, Woodman, SE, Wang, L, Andrews, MC, Wargo, J. Identification of microrna–mrna networks in melanoma and their association with pd-1 checkpoint blockade outcomes. Cancers 13(21), 2021. e-Pub 2021. PMID: 34771465.
80. Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, Bazzi S, Tran LM, Krysan K, Behrens C, Duose DY, Parra ER, Raso MG, Solis LM, Fukuoka J, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Rosen D, Heymach JV, Scheet P, Dubinett SM, Fujimoto J, Wistuba II, Stevenson CS, Spira A, Wang L, Kadara H. Resolving the spatial and cellular architecture of lung adenocarcinoma by multiregion single-cell sequencing. Cancer discovery 11(10):2506-2523, 2021. e-Pub 2021. PMID: 33972311.
81. Abbas HA, Hao D, Tomczak K, Barrodia P, Im JS, Reville PK, Alaniz Z, Wang W, Wang R, Wang F, Al-Atrash G, Takahashi K, Ning J, Ding M, Beird HC, Mathews JT, Little L, Zhang J, Basu S, Konopleva M, Marques-Piubelli ML, Solis LM, Parra ER, Lu W, Tamegnon A, Garcia-Manero G, Green MR, Sharma P, Allison JP, Kornblau SM, Rai K, Wang L, Daver N, Futreal A. Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy. Nature communications 12(1):6071, 2021. e-Pub 2021. PMID: 34663807.
82. Sloane RAS, White MG, Witt RG, Banerjee A, Davies MA, Han G, Burton E, Ajami N, Simon JM, Bernatchez C, Haydu LE, Tawbi HA, Gershenwald JE, Keung E, Ross M, McQuade J, Amaria RN, Wani K, Lazar AJ, Woodman SE, Wang L, Andrews MC, Wargo JA. Identification of MicroRNA–mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes. Cancers 13(21):5301, 2021. e-Pub 2021. PMID: 34771465.
83. Han G, Yang G, Hao D, Lu Y, Thein K, Simpson BS, Chen J, Sun R, Alhalabi O, Wang R, Dang M, Dai E, Zhang S, Nie F, Zhao S, Guo C, Hamza A, Czerniak B, Cheng C, Siefker-Radtke A, Bhat K, Futreal A, Peng G, Wargo J, Peng W, Kadara H, Ajani J, Swanton C, Litchfield K, Ahnert JR, Gao J, Wang L. 9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy. Nature communications 12(1):5606, 2021. e-Pub 2021. PMID: 34556668.
84. Del Poggetto E, Ho IL, Balestrieri C, Yen EY, Zhang S, Citron F, Shah R, Corti D, Diaferia GR, Li CY, Loponte S, Carbone F, Hayakawa Y, Valenti G, Jiang S, Sapio L, Jiang H, Dey P, Gao S, Deem AK, Rose-John S, Yao W, Ying H, Rhim AD, Genovese G, Heffernan TP, Maitra A, Wang TC, Wang L, Draetta GF, Carugo A, Natoli G, Viale A. Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis. Science 373(6561):eabj0486, 2021. e-Pub 2021. PMID: 34529467.
85. Bailey CP, Wang R, Figueroa M, Zhang S, Wang L, Chandra J. Computational immune infiltration analysis of pediatric high-grade gliomas (pHGGs) reveals differences in immunosuppression and prognosis by tumor location. Comput Syst Oncol 1(3):e1016, 2021. e-Pub 2021. PMID: 34723252.
86. Abbas, HA, Mohanty, V, Wang, R, Huang, Y, Liang, S, Wang, F, Zhang, J, Qiu, Y, Hu, CW, Qutub, A, Dail, M, Bolen, CR, Daver, N, Konopleva, M, Futreal, A, Chen, K, Wang, L, Kornblau, SM. Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes. Frontiers in Oncology 11, 2021. e-Pub 2021. PMID: 34422660.
87. Song S, Xu Y, Huo L, Zhao S, Wang R, Li Y, Scott AW, Pizzi MP, Wang Y, Fan Y, Harada K, Jin J, Ma L, Yao X, Shanbhag ND, Gan Q, Roy-Chowdhuri S, Badgwell BD, Wang Z, Wang L, Ajani JA. Patient-derived cell lines and orthotopic mouse model of peritoneal carcinomatosis recapitulate molecular and phenotypic features of human gastric adenocarcinoma. J Exp Clin Cancer Res 40(1):207, 2021. e-Pub 2021. PMID: 34162421.
88. Zhang S, Jiang VC, Han G, Hao D, Lian J, Liu Y, Zhang R, McIntosh J, Wang R, Dang M, Dai E, Wang Y, Santos D, Badillo M, Leeming A, Chen Z, Hartig K, Bigcal J, Zhou J, Kanagal-Shamanna R, Ok CY, Lee H, Steiner RE, Zhang J, Song X, Nair R, Ahmed S, Rodriquez A, Thirumurthi S, Jain P, Wagner-Bartak N, Hill H, Nomie K, Flowers C, Futreal A, Wang L, Wang M. Longitudinal Single-Cell Profiling Reveals Molecular Heterogeneity and Tumor-Immune Evolution in Refractory Mantle Cell Lymphoma. Nat Commun 12(1):2877, 2021. e-Pub 2021. PMID: 34001881.
89. Le X, Negrao MV, Reuben A, Federico L, Diao L, McGrail D, Nilsson M, Robichaux J, Munoz IG, Patel S, Elamin Y, Fan YH, Lee WC, Parra E, Solis Soto LM, Chen R, Li J, Karpinets T, Khairullah R, Kadara H, Behrens C, Sepesi B, Wang R, Zhu M, Wang L, Vaporiciyan A, Roth J, Swisher S, Haymaker C, Zhang J, Wang J, Wong KK, Byers LA, Bernatchez C, Zhang J, Wistuba II, Gibbons DL, Akbay EA, Heymach JV. Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target. Journal of Thoracic Oncology 16(4):583-600, 2021. e-Pub 2021. PMID: 33388477.
90. Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Scheet P, Fujimoto J, Shay J, Heymach JV, Minna JD, Dubinett S, Wistuba II, Stevenson CS, Spira AE, Wang L, Kadara H. Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers 13(6):1-13, 2021. e-Pub 2021. PMID: 33809063.
91. Hu X, Estecio MR, Chen R, Reuben A, Wang L, Fujimoto J, Carrot-Zhang J, McGranahan N, Ying L, Fukuoka J, Chow CW, Pham HHN, Godoy MCB, Carter BW, Behrens C, Zhang J, Antonoff MB, Sepesi B, Lu Y, Pass HI, Kadara H, Scheet P, Vaporciyan AA, Heymach JV, Wistuba II, Lee JJ, Futreal PA, Su D, Issa JJ, Zhang J. Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas. Nature communications 12(1):687, 2021. e-Pub 2021. PMID: 33514726.
92. Wheeler DA, Takebe N, Hinoue T, Hoadley KA, Cardenas MF, Hamilton AM, Laird PW, Wang L, Johnson A, Dewal N, Miller V, Piñeyro D, Castro de Moura M, Esteller M, Shen H, Zenklusen JC, Tarnuzzer R, McShane LM, Tricoli JV, Williams PM, Lubensky I, O'Sullivan-Coyne G, Kohn EC, Little RF, White J, Malik S, Harris L, Weil C, Chen AP, Karlovich C, Rodgers B, Shankar L, Jacobs P, Nolan T, Hu J, Muzny DM, Doddapaneni H, Korchina V, Gastier-Foster J, Bowen J, Leraas K, Edmondson EF, Doroshow JH, Conley BA, Ivy SP, Staudt LM. Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment. Cancer Cell 39(1):38-53.e7, 2021. e-Pub 2021. PMID: 33217343.
93. Conley BA, Staudt L, Takebe N, Wheeler DA, Wang L, Cardenas MF, Korchina V, Zenklusen JC, McShane LM, Tricoli JV, Williams PM, Lubensky I, O'Sullivan-Coyne G, Kohn E, Little RF, White J, Malik S, Harris LN, Mann B, Weil C, Tarnuzzer R, Karlovich C, Rodgers B, Shankar L, Jacobs PM, Nolan T, Berryman SM, Gastier-Foster J, Bowen J, Leraas K, Shen H, Laird PW, Esteller M, Miller V, Johnson A, Edmondson EF, Giordano TJ, Kim B, Ivy SP. The Exceptional Responders Initiative: Feasibility of A National Cancer Institute Pilot Study. Journal of the National Cancer Institute 113(1):27-37, 2021. e-Pub 2021. PMID: 32339229.
94. Wang R, Dang M, Harada K, Han G, Wang F, Pool Pizzi M, Zhao M, Tatlonghari G, Zhang S, Hao D, Lu Y, Zhao S, Badgwell BD, Blum Murphy M, Shanbhag N, Estrella JS, Roy-Chowdhuri S, Abdelhakeem AAF, Wang Y, Peng G, Hanash S, Calin GA, Song X, Chu Y, Zhang J, Li M, Chen K, Lazar AJ, Futreal A, Song S, Ajani JA, Wang L. Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma. Nature medicine 27(1):141-151, 2021. e-Pub 2021. PMID: 33398161.
95. Kim ST, Sheshadri A, Shannon V, Kontoyiannis DP, Kantarjian H, Garcia-Manero G, Ravandi F, Im JS, Boddu P, Bashoura L, Balachandran DD, Evans SE, Faiz S, Ruiz Vazquez W, Divenko M, Mathur R, Tippen SP, Gumbs C, Neelapu SS, Naing A, Wang L, Diab A, Futreal A, Nurieva R, Daver N. Distinct Immunophenotypes of T Cells in Bronchoalveolar Lavage Fluid From Leukemia Patients With Immune Checkpoint Inhibitors-Related Pulmonary Complications. Frontiers in immunology 11:590494, 2021. e-Pub 2021. PMID: 33552049.
96. Ajani JA, Xu Y, Huo L, Wang R, Li Y, Wang Y, Pizzi MP, Scott A, Harada K, Ma L, Yao X, Jin J, Zhao W, Dong X, Badgwell BD, Shanbhag N, Tatlonghari G, Estrella JS, Roy-Chowdhuri S, Kobayashi M, Vykoukal JV, Hanash SM, Calin GA, Peng G, Lee JS, Johnson RL, Wang Z, Wang L, Song S. YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition. Gut 70(1):55-66, 2021. e-Pub 2021. PMID: 32345613.
97. Deng Q, Han G, Puebla-Osorio N, Ma MCJ, Strati P, Chasen B, Dai E, Dang M, Jain N, Yang H, Wang Y, Zhang S, Wang R, Chen R, Showell J, Ghosh S, Patchva S, Zhang Q, Sun R, Hagemeister F, Fayad L, Samaniego F, Lee HC, Nastoupil LJ, Fowler N, Eric Davis R, Westin J, Neelapu SS, Wang L, Green MR. Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas. Nature medicine 26(12):1878-1887, 2020. e-Pub 2020. PMID: 33020644.
98. Sinjab A, Han G, Wang L, Kadara H. Field Carcinogenesis in Cancer Evolution: What the Cell Is Going On?. Cancer Research 80(22):4888-4891, 2020. e-Pub 2020. PMID: 33023945.
99. Farah M, Reuben A, Spassova I, Yang RK, Kubat L, Nagarajan P, Ning J, Li W, Aung PP, Curry JL, Torres-Cabala CA, Hudgens CW, Ugurel S, Schadendorf D, Gumbs C, Little LD, Futreal A, Wistuba II, Prieto VG, Wang L, Wong MK, Wargo JA, Becker JC, Tetzlaff MT. T-Cell Repertoire in Combination with T-Cell Density Predicts Clinical Outcomes in Patients with Merkel Cell Carcinoma. Journal of Investigative Dermatology 140(11):2146-2156.e4, 2020. e-Pub 2020. PMID: 32304704.
100. Maitituoheti M, Keung EZ, Tang M, Yan L, Alam H, Han G, Singh AK, Raman AT, Terranova C, Sarkar S, Orouji E, Amin SB, Sharma S, Williams M, Samant NS, Dhamdhere M, Zheng N, Shah T, Shah A, Axelrad JB, Anvar NE, Lin YH, Jiang S, Chang EQ, Ingram DR, Wang WL, Lazar A, Lee MG, Muller F, Wang L, Ying H, Rai K. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma. Cell Reports 33(3):108293, 2020. e-Pub 2020. PMID: 33086062.
101. Li Y, Song S, Pizzi MP, Han G, Scott AW, Jin J, Xu Y, Wang Y, Huo L, Ma L, Vellano C, Luo X, MacLeod R, Wang L, Wang Z, Ajani JA. LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma. Cancers 12(10):2995, 2020. e-Pub 2020. PMID: 33076512.
102. Bailey, M, Meyerson, WU, Dursi, LJ, Wang, LB, Dong, G, Liang, WW, Weerasinghe, A, Li, S, Kelso, S, Akbani, R, Anur, P, Bailey, MH, Buchanan, A, Chiotti, K, Covington, KR, Creason, A, Ding, L, Ellrott, K, Huse, J, Wang, W, Weinstein, JN, Chen, K, Chong, Z, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Park, K, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Yuan, Y, Zhu, H. Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature communications 11(1):4748, 2020. e-Pub 2020. PMID: 32958763.
103. Bailey CP, Figueroa M, Gangadharan A, Yang Y, Romero MM, Kennis BA, Yadavilli S, Henry V, Collier T, Monje M, Lee DA, Wang L, Nazarian J, Gopalakrishnan V, Zaky W, Becher OJ, Chandra J. Pharmacologic inhibition of lysine specific demethylase-1 (LSD1) as a therapeutic and immune-sensitization strategy in pediatric high grade glioma (pHGG). Neuro-oncology 22(9):1302-1314, 2020. e-Pub 2020. PMID: 32166329.
104. Li, CH, Prokopec, SD, Sun, RX, Yousif, F, Schmitz, N, Al-Shahrour, F, Atwal, G, Bailey, PJ, Biankin, AV, Boutros, PC, Campbell, PJ, Eils, R, Myklebost, O, Borresen-Dale, A, Plass, C, Akbani, R, Akdemir, KC, Aldape, KD, Broaddus, R, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Sex differences in oncogenic mutational processes. Nature communications 11(1):4330, 2020. e-Pub 2020. PMID: 32859912.
105. Lulla PD, Tzannou I, Vasileiou S, Carrum G, Ramos CA, Kamble R, Wang T, Wu M, Bilgi M, Gee AP, Mukhi S, Chung B, Wang L, Watanabe A, Kuvalekar M, Jeong M, Li Y, Ketkar S, French-Kim M, Grilley B, Brenner MK, Heslop HE, Vera JF, Leen AM. The safety and clinical effects of administering a multiantigen-targeted T cell therapy to patients with multiple myeloma. Sci Transl Med 12(554), 2020. e-Pub 2020. PMID: 32727914.
106. Li Y, Yang S, Sadaoui NC, Hu W, Dasari SK, Mangala LS, Sun Y, Zhao S, Wang L, Liu Y, Ramondetta LM, Li K, Lu C, Kang Y, Cole SW, Lutgendorf SK, Sood AK. Sustained Adrenergic Activation of YAP1 Induces Anoikis Resistance in Cervical Cancer Cells. iScience 23(7):101289, 2020. e-Pub 2020. PMID: 32623336.
107. Zhao S, Kanagal-Shamanna R, Navsaria L, Ok CY, Zhang S, Nomie K, Han G, Hao D, Hill HA, Jiang C, Yao Y, Nastoupil L, Westin J, Fayad L, Nair R, Steiner R, Ahmed S, Samaniego F, Iyer SP, Oriabure O, Chen W, Song X, Zhang J, Badillo M, Moghrabi O, Aranda J, Tang G, Yin CC, Patel K, Medeiros LJ, Li S, Vega F, Thirumurthi S, Xu G, Neelapu S, Flowers CR, Romaguera J, Fowler N, Wang L, Wang ML, Jain P. Efficacy of venetoclax in high risk relapsed mantle cell lymphoma (MCL) - outcomes and mutation profile from venetoclax resistant MCL patients. American journal of hematology 95(6):623-629, 2020. e-Pub 2020. PMID: 32239765.
108. Lu Y, Wang L, Ajani JA. Rare Esophageal Leptomeningeal Metastases Detected on 18F-FDG PET/CT. Clin Nucl Med 45(4):334-335, 2020. e-Pub 2020. PMID: 31977493.
109. Jain P, Zhang S, Kanagal-Shamanna R, Ok CY, Nomie K, Gonzalez GN, Gonzalez-Pagan O, Hill HA, Lee HJ, Fayad L, Westin J, Nastoupil L, Hagemeister F, Chen W, Oriabure O, Badillo M, Jiang C, Yixin Y, Li S, Tang G, Yin CC, Patel KP, Medeiros LJ, Nair R, Ahmed S, Iyer SP, Thirumurthi S, Champlin R, Xu G, Tinsu P, Santos D, Wang R, Han G, Zhang J, Song X, Neelapu S, Romaguera J, Futreal A, Flowers C, Fowler N, Wang L, Wang ML. Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL. Blood Advances 4(6):1038-1050, 2020. e-Pub 2020. PMID: 32191807.
110. Naing A, Meric-Bernstam F, Stephen B, Karp DD, Hajjar J, Rodon Ahnert J, Piha-Paul SA, Colen RR, Jimenez C, Raghav KP, Ferrarotto R, Tu SM, Campbell M, Wang L, Sabir SH, Tapia C, Bernatchez C, Frumovitz M, Tannir N, Ravi V, Khan S, Painter JM, Abonofal A, Gong J, Alshawa A, McQuinn LM, Xu M, Ahmed S, Subbiah V, Hong DS, Pant S, Yap TA, Tsimberidou AM, Dumbrava EEI, Janku F, Fu S, Simon RM, Hess KR, Varadhachary GR, Habra MA. Phase 2 study of pembrolizumab in patients with advanced rare cancers. Journal for immunotherapy of cancer 8(1):e000347, 2020. e-Pub 2020. PMID: 32188704.
111. Cmero, M, Yuan, K, Ong, CS, Schröder, J, Adams, DJ, Anur, P, Beroukhim, R, Boutros, PC, Bowtell, DD, Campbell, PJ, Cao, S, Christie, EL, Cun, Y, Dawson, KJ, Demeulemeester, J, Eils, R, Fan, Y, Van Loo, P, Wang, W, Zhu, H, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Chakravarty, D, Chen, K, Chen, Y, Czerniak, BA, El-Naggar, AK, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Wang, L, Weinstein, JN, Yuan, Y. Inferring structural variant cancer cell fraction. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024845.
112. Sieverling, L, Hong, C, Koser, S, Ginsbach, P, Kleinheinz, K, Hutter, B, Braun, DM, Cortés-Ciriano, I, Xi, R, Kabbe, R, Park, PJ, Eils, R, Schlesner, M, Akdemir, KC, Alvarez, EG, Chen, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Genomic footprints of activated telomere maintenance mechanisms in cancer. Nature communications 11(1):733, 2020. e-Pub 2020. PMID: 32024817.
113. Paczkowska, M, Barenboim, J, Sintupisut, N, Fox, NS, Zhu, H, Abd-Rabbo, D, Mee, MW, Boutros, PC, Abascal, F, Amin, S, Bader, GD, Beroukhim, R, Bertl, J, Boroevich, KA, Chakravarty, D, Chen, K, Park, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Integrative pathway enrichment analysis of multivariate omics data. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32024846.
114. Shuai, S, Abascal, F, Amin, S, Bader, GD, Bandopadhayay, P, Barenboim, J, Beroukhim, R, Bertl, J, Boroevich, KA, Brunak, S, Campbell, PJ, Carlevaro-Fita, J, Chakravarty, D, Chan, CY, Chen, K, Choi, JK, Deu-Pons, J, Dhingra, P, Park, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Combined burden and functional impact tests for cancer driver discovery using DriverPower. Nature communications 11(1):734, 2020. e-Pub 2020. PMID: 32024818.
115. Jiao, W, Atwal, G, Polak, P, Karlic, R, Cuppen, E, Al-Shahrour, F, Atwal, G, Bailey, PJ, Biankin, AV, Boutros, PC, Campbell, PJ, Chang, DK, Cooke, SL, Lazar, A, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nature communications 11(1):728, 2020. e-Pub 2020. PMID: 32024849.
116. Zhang, Y, Chen, F, Fonseca, NA, He, Y, Fujita, M, Nakagawa, H, Zhang, Z, Brazma, A, Amin, SB, Awadalla, P, Bailey, PJ, Brazma, A, Brooks, AN, Calabrese, C, Chateigner, A, Cortés-Ciriano, I, Akdemir, KC, Chen, K, Akbani, R, Aldape, KD, Broaddus, R, Borresen-Dale, A, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nature communications 11(1):736, 2020. e-Pub 2020. PMID: 32024823.
117. Rubanova, Y, Shi, R, Harrigan, CF, Li, R, Wintersinger, J, Sahin, N, Deshwar, AG, Dentro, SC, Leshchiner, I, Gerstung, M, Jolly, C, Haase, K, Tarabichi, M, Wintersinger, J, Cao, S, Eils, R, Fan, Y, Zhu, H, Wang, W, Van Loo, P, Akbani, R, Aldape, KD, Borresen-Dale, A, Chakravarty, D, Chen, K, Chen, Y, Czerniak, BA, El-Naggar, AK, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Myklebost, O, Park, K, Plass, C, Sood, AK, Su, X, Thompson, A, Wang, L, Weinstein, JN, Yuan, Y. Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. Nature communications 11(1):731, 2020. e-Pub 2020. PMID: 32024834.
118. Reyna, MA, Haan, D, Paczkowska, M, Verbeke, LP, Vazquez, M, Kahraman, A, Pulido-Tamayo, S, Barenboim, J, Wadi, L, Dhingra, P, Shrestha, R, Getz, G, Lawrence, MS, Pedersen, JS, Rubin, MA, Chakravarty, D, Chen, K, Park, K, Akbani, R, Aldape, KD, Borresen-Dale, A, Cao, S, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Plass, C, Sood, AK, Su, X, Thompson, A, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H. Pathway and network analysis of more than 2500 whole cancer genomes. Nature communications 11(1):729, 2020. e-Pub 2020. PMID: 32024854.
119. Genomes Consortium IPAOW. Pan-cancer analysis of whole genomes. Nature 578(7793):82-93, 2020. e-Pub 2020. PMID: 32025007.
120. Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, Cogdill AP, Liu W, LeBleu VS, Kugeratski FG, Patel S, Davies MA, Hwu P, Lee JE, Gershenwald JE, Lucci A, Arora R, Woodman S, Keung EZ, Gaudreau PO, Reuben A, Spencer CN, Burton EM, Haydu LE, Lazar AJ, Zapassodi R, Hudgens CW, Ledesma DA, Ong S, Bailey M, Warren S, Rao D, Krijgsman O, Rozeman EA, Peeper D, Blank CU, Schumacher TN, Butterfield LH, Zelazowska MA, McBride KM, Kalluri R, Allison J, Petitprez F, Fridman WH, Sautès-Fridman C, Hacohen N, Rezvani K, Sharma P, Tetzlaff MT, Wang L, Wargo JA. B cells and tertiary lymphoid structures promote immunotherapy response. Nature 577(7791):549-555, 2020. e-Pub 2020. PMID: 31942075.
121. Wang R, Song S, Harada K, Ghazanfari Amlashi F, Badgwell B, Pizzi MP, Xu Y, Zhao W, Dong X, Jin J, Wang Y, Scott A, Ma L, Huo L, Vicente D, Blum Murphy M, Shanbhag N, Tatlonghari G, Thomas I, Rogers J, Kobayashi M, Vykoukal J, Estrella JS, Roy-Chowdhuri S, Han G, Zhang S, Mao X, Song X, Zhang J, Gu J, Johnson RL, Calin GA, Peng G, Lee JS, Hanash SM, Futreal A, Wang Z, Wang L, Ajani JA. Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response. Gut 69(1):18-31, 2020. e-Pub 2020. PMID: 31171626.
122. Xu Y, Li Y, Jin J, Han G, Sun C, Pizzi MP, Huo L, Scott A, Wang Y, Ma L, Lee JH, Bhutani MS, Weston B, Vellano C, Yang L, Lin C, Kim Y, MacLeod AR, Wang L, Wang Z, Song S, Ajani JA. LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma. Molecular cancer 18(1):141, 2019. e-Pub 2019. PMID: 31601234.
123. Liu J, Huang Z, Yang L, Wang X, Wang S, Li C, Liu Y, Cheng Y, Wang B, Sang X, He X, Wang C, Liu T, Liu C, Jin L, Liu C, Zhang X, Wang L, Wang Z. Embryonic Stem Cells Modulate the Cancer-Permissive Microenvironment of Human Uveal Melanoma. Theranostics 9(16):4764-4778, 2019. e-Pub 2019. PMID: 31367256.
124. Reddy SM, Reuben A, Barua S, Jiang H, Zhang S, Wang L, Gopalakrishnan V, Hudgens CW, Tetzlaff MT, Reuben JM, Tsujikawa T, Coussens LM, Wani K, He Y, Villareal L, Wood A, Rao A, Woodward WA, Ueno NT, Krishnamurthy S, Wargo JA, Mittendorf EA. Poor Response to Neoadjuvant Chemotherapy Correlates with Mast Cell Infiltration in Inflammatory Breast Cancer. Cancer Immunol Res 7(6):1025-1035, 2019. e-Pub 2019. PMID: 31043414.
125. Zhang L, Yao Y, Zhang S, Liu Y, Guo H, Ahmed M, Bell T, Zhang H, Han G, Lorence E, Badillo M, Zhou S, Sun Y, Di Francesco ME, Feng N, Haun R, Lan R, Mackintosh SG, Mao X, Song X, Zhang J, Pham LV, Lorenzi PL, Marszalek J, Heffernan T, Draetta G, Jones P, Futreal A, Nomie K, Wang L, Wang M. Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma. Science translational medicine 11(491):eaau1167, 2019. e-Pub 2019. PMID: 31068440.
126. Li F, Xu Y, Liu B, Singh PK, Zhao W, Jin J, Han G, Scott AW, Dong X, Huo L, Ma L, Pool Pizzi M, Wang Y, Li Y, Harada K, Xie M, Skinner HD, Ding S, Wang L, Krishnan S, Johnson RL, Song S, Ajani JA. YAP1-mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer - Rationale for the combination of YAP1 and CDK4/6 inhibitors in Esophageal Cancer. Clinical Cancer Research 25(7):2264-2277, 2019. e-Pub 2019. PMID: 30563933.
127. Manasanch EE, Han G, Mathur R, Qing Y, Zhang Z, Lee H, Weber DM, Amini B, Berkova Z, Eterovic K, Zhang S, Zhang J, Song X, Mao X, Morgan M, Feng L, Baladandayuthapani V, Futreal A, Wang L, Neelapu SS, Orlowski RZ. A pilot study of pembrolizumab in smoldering myeloma: report of the clinical, immune, and genomic analysis. Blood Advances 3(15):2400-2408, 2019. e-Pub 2019. PMID: 31405950.
128. Looney, TJ, Duose, D, Lowman, G, Linch, E, Hajjar, J, Topacio-Hall, D, Xu, M, Zheng, J, Alshawa, A, Tapia, C, Stephen, B, Wang, L, Meric-Bernstam, F, Miller, L, Glavin, A, Lin, L, Gong, J, Conroy, J, Morrison, C, Hyland, FC, Naing, A. Haplotype analysis of the t-cell receptor beta (Tcrb) locus by long-amplicon tcrb repertoire sequencing. Journal of Immunotherapy and Precision Oncology 2(4):137-143, 2019. e-Pub 2019.
129. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nature medicine 24(11):1649-1654, 2018. e-Pub 2018. PMID: 30297909.
130. Jain P, Kanagal-Shamanna R, Zhang S, Ahmed M, Ghorab A, Zhang L, Ok CY, Li S, Hagemeister F, Zeng D, Gong T, Chen W, Badillo M, Nomie K, Fayad L, Medeiros LJ, Neelapu S, Fowler N, Romaguera J, Champlin R, Wang L, Wang ML. Long-term outcomes and mutation profiling of patients with mantle cell lymphoma (MCL) who discontinued ibrutinib. British Journal of Haematology 183(4):578-587, 2018. e-Pub 2018. PMID: 30175400.
131. Wang, Y, Mojumdar, K, Peng, X, Ge, Z, Li, J, Han, L, Mills, GB, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Liang, H, Ling, S, Liu, W, Lu, Y, Uppore Kukkillaya, AR, Wang, J, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer. Cell Reports 25(5):1304-1317.e5, 2018. e-Pub 2018. PMID: 30380420.
132. Korkut, A, Kanchi, RS, Li, X, Lorenzi, PL, Kwong, L, Roszik, J, Ling, S, Uppore Kukkillaya, AR, Liu, Y, Ju, Z, Hansel, DE, Li, S, Ajani, JA, Mani, S, Chen, J, Ma, W, Zhang, J, Broom, BM, Li, J, Liang, H, Liu, W, Lu, Y, Mills, GB, Weinstein, JN, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Mishra, L, Akbani, R. A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily. Cell Systems 7(4):422-437.e7, 2018. e-Pub 2018. PMID: 30268436.
133. Kahles, A, Lehmann, KV, Toussaint, NC, Hüser, M, Stark, SG, Sachsenberg, T, Stegle, O, Kohlbacher, O, Sander, C, Caesar-Johnson, SJ, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II. Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients. Cancer cell 34(2):211-224.e6, 2018. e-Pub 2018. PMID: 30078747.
134. Lefrançois P, Xie P, Wang L, Tetzlaff MT, Moreau L, Watters AK, Netchiporouk E, Provost N, Gilbert M, Ni X, Sasseville D, Wheeler DA, Duvic M, Litvinov IV. Gene expression profiling and immune cell-type deconvolution highlight robust disease progression and survival markers in multiple cohorts of CTCL patients. Oncoimmunology 7(8):e1467856, 2018. e-Pub 2018. PMID: 30221071.
135. Shen H, Shih J, Hollern DP, Wang L, Bowlby R, Tickoo SK, Thorsson V, Mungall AJ, Newton Y, Hegde AM, Armenia J, Sánchez-Vega F, Pluta J, Pyle LC, Mehra R, Reuter VE, Godoy G, Jones J, Shelley CS, Feldman DR, Vidal DO, Lessel D, Kulis T, Cárcano FM, Leraas KM, Lichtenberg TM, Brooks D, Cherniack AD, Cho J, Heiman DI, Kasaian K, Liu M, Noble MS, Xi L, Zhang H, Zhou W, ZenKlusen JC, Hutter CM, Felau I, Zhang J, Schultz N, Getz G, Meyerson M, Stuart JM, Research Network CGA, Akbani R, Wheeler DA, Laird PW, Nathanson KL, Cortessis VK, Hoadley KA. Integrated molecular characterization of testicular germ cell tumors. Cell Reports 23(11):3392-3406, 2018. e-Pub 2018. PMID: 29898407.
136. Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CE, Research Network CGA, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich L. The Immune Landscape of Cancer. Immunity 48(4):812-830.e14, 2018. e-Pub 2018. PMID: 29628290.
137. Wang, Z, Yang, B, Zhang, M, Guo, W, Wu, Z, Wang, Y, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer cell 33(4):706-720.e9, 2018. e-Pub 2018. PMID: 29622465.
138. Berger, AC, Korkut, A, Kanchi, RS, Hegde, A, Lenoir, W, Liu, W, Liu, Y, Uppore Kukkillaya, AR, Li, X, Sood, AK, Lazar, A, Baggerly, KA, Roszik, J, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Li, J, Liang, H, Ling, S, Lu, Y, Mills, GB, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer cell 33(4):690-705.e9, 2018. e-Pub 2018. PMID: 29622464.
139. Liu, Y, Sethi, NS, Hinoue, T, Schneider, BG, Cherniack, AD, Sanchez-Vega, F, Seoane, JA, Farshidfar, F, Akbani, R, Kanchi, RS, Mishra, L, Lazar, A, Wistuba, II, Liu, Y, Zhang, W, Broom, BM, Ju, Z, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer cell 33(4):721-735.e8, 2018. e-Pub 2018. PMID: 29622466.
140. Malta, TM, Sokolov, A, Gentles, AJ, Burzykowski, T, Poisson, LM, Weinstein, JN, Kaminska, B, Huelsken, J, Mishra, L, Lazar, A, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell 173(2):338-354.e15, 2018. e-Pub 2018. PMID: 29625051.
141. Chen, H, Li, C, Peng, X, Zhou, Z, Weinstein, JN, Caesar-Johnson, SJ, Demchok, JA, Felau, I, Kasapi, M, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Liang, H. A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. Cell 173(2):386-399.e12, 2018. e-Pub 2018. PMID: 29625054.
142. Liu, J, Lichtenberg, TM, Hoadley, KA, Poisson, LM, Lazar, A, Cherniack, AD, Kovatich, AJ, Scapulatempo, CN, Wistuba, II, Carvalho, AL, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, von Deimling, A. An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell 173(2):400-416.e11, 2018. e-Pub 2018. PMID: 29625055.
143. Huang, KL, Mashl, RJ, Wu, Y, Ritter, DI, Wang, J, Oh, C, Paczkowska, M, Kim, T, Logothetis, CJ, Wistuba, II, Chen, K, Liu, Y, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, von Deimling, A, Meric-Bernstam, F. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell 173(2):355-370.e14, 2018. e-Pub 2018. PMID: 29625052.
144. Ding, L, Bailey, M, Porta-Pardo, E, Thorsson, V, Colaprico, A, Bertrand, D, Akbani, R, Mills, GB, Lazar, A, Liu, Y, Zhang, W, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell 173(2):305-320.e10, 2018. e-Pub 2018. PMID: 29625049.
145. Bailey, M, Tokheim, C, Porta-Pardo, E, Sengupta, S, Wang, Z, Liang, H, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Chen, K. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell 173(2):371-385.e18, 2018. e-Pub 2018. PMID: 29625053.
146. Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Research Network CGA, Monnat RJ, Xiao Y, Wang C. Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas. Cell Reports 23(1):239-254.e6, 2018. e-Pub 2018. PMID: 29617664.
147. Peng, X, Chen, Z, Farshidfar, F, Xu, X, Lorenzi, PL, Tan, L, Mojumdar, K, Ge, Z, Weinstein, JN, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Liang, H. Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. Cell Reports 23(1):255-269.e4, 2018. e-Pub 2018. PMID: 29617665.
148. Chiu, HS, Somvanshi, S, Patel, E, Chen, TW, Singh, VP, Zorman, B, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Sood, AK. Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Reports 23(1):297-312.e12, 2018. e-Pub 2018. PMID: 29617668.
149. Jayasinghe, R, Cao, S, Gao, Q, Wendl, MC, Vo, NS, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Chen, K. Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Reports 23(1):270-281.e3, 2018. e-Pub 2018. PMID: 29617666.
150. Campbell, JD, Yau, C, Liu, Y, Akbani, R, Byers, LA, Kanchi, RS, Gay, CM, Diao, L, Ma, W, Lazar, A, Flores, ER, Tsai, KY, Wistuba, II, Zhang, W, Broom, BM, Ju, Z, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Pickering, CR. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports 23(1):194-212.e6, 2018. e-Pub 2018. PMID: 29617660.
151. Ge, Z, Leighton, J, Peng, X, Sun, Y, Yao, F, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Piwnica-Worms, H, Ma, L, Liang, H. Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Reports 23(1):213-226.e3, 2018. e-Pub 2018. PMID: 29617661.
152. Seiler, M, Peng, S, Agrawal, AA, Palacino, J, Teng, T, Zhu, P, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types. Cell Reports 23(1):282-296.e4, 2018. e-Pub 2018. PMID: 29617667.
153. Ricketts, CJ, de Cubas, AA, Fan, H, Smith, CC, Lang, M, Reznik, E, Akbani, R, Kanchi, RS, Mills, GB, Tamboli, P, Liu, Y, Zhang, W, Broom, BM, Ju, Z, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports 23(1):313-326.e5, 2018. e-Pub 2018. PMID: 29617669.
154. Gao, Q, Liang, WW, Foltz, SM, Mutharasu, G, Jayasinghe, R, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A, Chen, K. Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Reports 23(1):227-238.e3, 2018. e-Pub 2018. PMID: 29617662.
155. Ellrott, K, Bailey, M, Saksena, G, Covington, KR, Kandoth, C, Stewart, C, Liu, Y, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Carvalho, AL, Fregnani, JG, Reis, RV, Scapulatempo, CN, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, Wistuba, II, von Deimling, A. Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Systems 6(3):271-281.e7, 2018. e-Pub 2018. PMID: 29596782.
156. Schaub, FX, Dhankani, V, Berger, AC, Trivedi, M, Richardson, AB, Shaw, R, Zhao, W, Zhang, X, Liu, Y, Wistuba, II, Zhang, W, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L, Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Logothetis, CJ, Meric-Bernstam, F, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, von Deimling, A. Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems 6(3):282-300.e2, 2018. e-Pub 2018. PMID: 29596783.
157. Cancer Genome Atlas Research Network. Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell 169(7):1327-1341.e23, 2017. e-Pub 2017. PMID: 28622513.
158. Goschzik T, Gessi M, Dreschmann V, Gebhardt U, Wang L, Yamaguchi S, Wheeler DA, Lauriola L, Lau CC, Müller HL, Pietsch T. Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma. Journal of neuropathology and experimental neurology 76(2):126-134, 2017. e-Pub 2017. PMID: 28069929.
159. Eckstein OS, Wang L, Punia JN, Kornblau SM, Andreeff M, Wheeler DA, Goodell MA, Rau RE. Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. Experimental Hematology 44(8):740-4, 2016. e-Pub 2016. PMID: 27208809.
160. Wang L, Ni X, Covington KR, Yang BY, Shiu J, Zhang X, Xi L, Meng Q, Langridge T, Drummond J, Donehower LA, Doddapaneni H, Muzny DM, Gibbs RA, Wheeler DA, Duvic M. Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes. Nat Genet 47(12):1426-34, 2015. e-Pub 2015. PMID: 26551670.
161. Chakraborty R, Hampton OA, Shen X, Simko SJ, Shih A, Abhyankar H, Lim KP, Covington KR, Trevino L, Dewal N, Muzny DM, Doddapaneni H, Hu J, Wang L, Lupo PJ, Hicks MJ, Bonilla DL, Dwyer KC, Berres ML, Poulikakos PI, Merad M, McClain KL, Wheeler DA, Allen CE, Parsons DW. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis. Blood 124(19):3007-15, 2014. e-Pub 2014. PMID: 25202140.
162. Arai E, Sakamoto H, Ichikawa H, Totsuka H, Chiku S, Gotoh M, Mori T, Nakatani T, Ohnami S, Nakagawa T, Fujimoto H, Wang L, Aburatani H, Yoshida T, Kanai Y. Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome. International journal of cancer 135(6):1330-1342, 2014. e-Pub 2014. PMID: 24504440.
163. Wang L, Swierczek SI, Drummond J, Hickman K, Kim SJ, Walker K, Doddapaneni H, Muzny DM, Gibbs RA, Wheeler DA, Prchal JT. Whole-exome sequencing of polycythemia vera revealed novel driver genes and somatic mutation shared by T cells and granulocytes. Leukemia 28(4):935-938, 2014. e-Pub 2014. PMID: 24413320.
164. Wang L, Swierczek SI, Lanikova L, Kim SJ, Hickman K, Walker K, Wang K, Drummond J, Doddapaneni H, Reid JG, Muzny DM, Gibbs RA, Wheeler DA, Prchal JT. The relationship of JAK2(V617F) and acquired UPD at chromosome 9p in polycythemia vera. Leukemia 28(4):938-941, 2014. e-Pub 2014. PMID: 24463469.
165. Wang L, Yamaguchi S, Burstein MD, Terashima K, Chang K, Ng HK, Nakamura H, He Z, Doddapaneni H, Lewis L, Wang M, Suzuki T, Nishikawa R, Natsume A, Terasaka S, Dauser R, Whitehead W, Adekunle A, Sun J, Qiao Y, Marth G, Muzny DM, Gibbs RA, Leal SM, Wheeler DA, Lau CC. Novel somatic and germline mutations in intracranial germ cell tumours. Nature 511(7508):241-245, 2014. e-Pub 2014. PMID: 24896186.
166. Ikeda Y, Oda K, Nakagawa S, Murayama-Hosokawa S, Yamamoto S, Ishikawa S, Wang L, Takazawa Y, Maeda D, Wada-Hiraike O, Kawana K, Fukayama M, Aburatani H, Yano T, Kozuma S, Taketani Y. Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer. International Journal of Gynecological Cancer 22(5):725-731, 2012. e-Pub 2012. PMID: 22635024.
167. Wang L, Tsutsumi S, Kawaguchi T, Nagasaki K, Tatsuno K, Yamamoto S, Sang F, Sonoda K, Sugawara M, Saiura A, Hirono S, Yamaue H, Miki Y, Isomura M, Totoki Y, Nagae G, Isagawa T, Ueda H, Murayama-Hosokawa S, Shibata T, Sakamoto H, Kanai Y, Kaneda A, Noda T, Aburatani H. Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. Genome research 22(2):208-219, 2012. e-Pub 2012. PMID: 22156295.
168. Totoki Y, Tatsuno K, Yamamoto S, Arai Y, Hosoda F, Ishikawa S, Tsutsumi S, Sonoda K, Totsuka H, Shirakihara T, Sakamoto H, Wang L, Ojima H, Shimada K, Kosuge T, Okusaka T, Kato K, Kusuda J, Yoshida T, Aburatani H, Shibata T. High-resolution characterization of a hepatocellular carcinoma genome. Nature Genetics 43(5):464-471, 2011. e-Pub 2011. PMID: 21499249.

Invited Articles

1. Liu Y, Dai Y, Wang L. Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications. Cancer Cell 44(1):24-49, 2026. e-Pub 2026. PMID: 41478277.
2. Pei, G, Liu, Y, Wang, L. Spatially resolving cancer: from cell states to therapy. Trends in Cancer 12(1):20-33, 2026. e-Pub 2026. PMID: 41044012.
3. Gulati GS, D'Silva JP, Liu Y, Wang L, Newman AM. Profiling cell identity and tissue architecture with single-cell and spatial transcriptomics. Nat Rev Mol Cell Biol 26(1):11-31, 2024. e-Pub 2024. PMID: 39169166.
4. Wang L, Li M, Hwang TH. The 3D Revolution in Cancer Discovery. Cancer Discov 14(4):625-629, 2024. e-Pub 2024. PMID: 38571426.
5. Hirata Y, Noorani A, Song S, Wang L, Ajani JA. Early stage gastric adenocarcinoma: clinical and molecular landscapes. Nat Rev Clin Oncol 20(7):453-469, 2023. e-Pub 2023. PMID: 37264184.
6. Wang L, Ajani JA. Ushering in Liquid Biopsy for the Microsatellite Status: Advantages and Caveats. Clinical Cancer Research 25(23):6887-6889, 2019. e-Pub 2019. PMID: 31527165.
7. Wang L, Wheeler DA, Prchal JT. Acquired uniparental disomy of chromosome 9p in hematologic malignancies. Experimental Hematology 44(8):644-652, 2016. e-Pub 2016. PMID: 26646991.
8. Wang L, Wheeler DA. Genomic sequencing for cancer diagnosis and therapy. Annual Review of Medicine 65:33-48, 2014. e-Pub 2014. PMID: 24274147.
9. Wheeler DA, Wang L. From human genome to cancer genome: the first decade. Genome research 23(7):1054-62, 2013. e-Pub 2013. PMID: 23817046.
10. Aburatani H, Wang L. Integrated genomic analysis of pancreatic ductal carcinoma. Experimental Medicine 30:33-38, 2012. e-Pub 2012.

Editorials

1. Wang L, Qu J, Harari O, Boddey JA, Wang Z, Linna-Kuosmanen S. The impact of multi-omics in medicine. Cell Rep Med 5(9):101742, 2024. PMID: 39293398.
2. Theis FJ, Dar D, Vento-Tormo R, Vickovic S, Wang L, Kagohara LT, Rendeiro AF, Joyce JA. What do you most hope spatial molecular profiling will help us understand? Part 1. Cell Systems 14(6):423-427, 2023. PMID: 37348459.
3. Wang L. Stress response in tumor-infiltrating T cells is linked to immunotherapy resistance. Nat Med 29(6):1336-1337, 2023. PMID: 37253923.
4. Wang L. Developmental Deconvolution Suggests New Tumor Biology and a Tool for Predicting Cancer Origin. Cancer Discov 12(11):2498-2500, 2022. PMID: 36321308.
5. Anderson AC, Yanai I, Yates LR, Wang L, Swarbrick A, Sorger P, Santagata S, Fridman WH, Gao Q, Jerby L, Izar B, Shang L, Zhou X. Spatial transcriptomics. Cancer Cell 40(9):895-900, 2022. PMID: 36099884.

Letters to the Editor

1. Li X, Henderson J, Gordon MJ, Sheikh I, Nastoupil LJ, Westin J, Flowers C, Ahmed S, Wang L, Neelapu SS, Strati P, Deng Q, Green MR. A single-cell atlas of CD19 chimeric antigen receptor T cells. Cancer Cell 41: 1835-1837, 2023.
2. Plaks V, Rossi JM, Chou J, Wang L, Poddar S, Han G, Wang Z, Kuang SQ, Chu F, Davis RE, Vega F, Bashir Z, Jacobson CA, Locke FL, Reagan P, Rodig SJ, Lekakis LJ, Flinn IW, Miklos DB, Bot A, Neelapu SS. CD19 target evasion as a mechanism of relapse in large B-cell lymphoma treated with axicabtagene ciloleucel. Blood 138: 1081-1085, 2021.
3. Jain P, Kanagal-Shamanna R, Zhang S, Ok CY, Navsaria L, Nastoupil L, Lee HJ, Tang G, Yin CC, Badillo M, Nair R, Li S, Patel KM, Flowers C, Vega F, Wang L, Wang ML. Outcomes of relapsed mantle cell lymphoma patients after discontinuing acalabrutinib. American journal of hematology 96: E137-E140, 2021.
4. Lanikova L, Babosova O, Swierczek S, Wang L, Wheeler DA, Divoky V, Korinek V, Prchal JT. Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera. Blood 128: 2266-2270, 2016.