Lynette M. Phillips, Ph.D.
Department of Oncology Care & Research IS, Division of Information Services
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Neurosurgery - Research, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2007 | Baylor College of Medicine, Houston, TX, USA, PHD, Molecular and Cellular Biology |
| 1999 | University of Notre Dame, Notre Dame, IN, USA, BS, Biology |
Postgraduate Training
| 2007-2012 | Postdoctoral Fellow, The University of Texas MD Anderson Cancer Center, Houston, TX |
Experience & Service
Academic Appointments
Instructor, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2019
Honors & Awards
| 2014 | Caroline Ross Endowment Fellowship in Brain Cancer Research, MD Anderson Cancer Center Brain Tumor Center |
| 2009 | Adult Basic Science Award, Society for Neuro-Oncology and AANS/CNS Section on Tumors |
| 2001 | Anthony R. Means Award for Academic Excellence, Department of Molecular and Cellular Biology. Baylor College of Medicine |
Selected Publications
Peer-Reviewed Articles
- Phillips LM, Li S, Gumin J, Daou M, Ledbetter D, Yang J, Singh S, Parker Kerrigan BC, Hossain A, Yuan Y, Gomez-Manzano C, Fueyo J, Lang FF. An immune-competent, replication-permissive Syrian Hamster glioma model for evaluating Delta-24-RGD oncolytic adenovirus. Neuro Oncol. e-Pub 2021. PMID: 34059921.
- Parker Kerrigan BC, Ledbetter D, Kronowitz M, Phillips L, Gumin J, Hossain A, Yang J, Mendt M, Singh S, Cogdell D, Ene C, Shpall E, Lang FF. RNAi technology targeting the FGFR3-TACC3 fusion breakpoint: an opportunity for precision medicine. Neurooncol Adv 2(1):vdaa132, 2020. e-Pub 2020. PMID: 33241214.
- Figueroa J, Phillips LM, Shahar T, Hossain A, Gumin J, Kim H, Bean AJ, Calin GA, Fueyo J, Walters ET, Kalluri R, Verhaak RG, Lang FF. Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587. Cancer Res 77(21):5808-5819, 2017. e-Pub 2017. PMID: 28855213.
- Phillips LM, Zhou X, Cogdell DE, Chua CY, Huisinga A, R Hess K, Fuller GN, Zhang W. Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies. J Pathol 239(3):355-64, 2016. e-Pub 2016. PMID: 27125842.
- Li X, Liu Y, Granberg KJ, Wang Q, Moore LM, Ji P, Gumin J, Sulman EP, Calin GA, Haapasalo H, Nykter M, Shmulevich I, Fuller GN, Lang FF, Zhang W.. Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma. Oncogene 34(13):1619-28, 2014. PMID: 24747968.
- Moore LM, Kivinen V, Liu Y, Annala M, Cogdell D, Liu X, Liu CG, Sawaya R, Yli-Harja O, Shmulevich I, Fuller GN, Zhang W, Nykter M. Transcriptome and small RNA deep sequencing reveals deregulation of miRNA biogenesis in human glioma. J Pathol 229(3):449-59, 2013. PMID: 23007860.
- Holmes KM, Annala M, Chua CY, Dunlap SM, Liu Y, Hugen N, Moore LM, Cogdell D, Hu L, Nykter M, Hess K, Fuller GN, Zhang W. Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network. Proc Natl Acad Sci U S A 109(9):3475-80, 2012. e-Pub 2012. PMID: 22345562.
- Moore LM, Holmes KM, Smith SM, Wu Y, Tchougounova E, Uhrbom L, Sawaya R, Bruner JM, Fuller GN, Zhang W. IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas. Proc Natl Acad Sci U S A 106(39):16675-9, 2009. e-Pub 2009. PMID: 19805356.
- Dumble M, Moore L, Chambers SM, Geiger H, Van Zant G, Goodell MA, Donehower LA. The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood 109(4):1736-42, 2007. e-Pub 2006. PMID: 17032926.
- Moore L, Venkatachalam S, Vogel H, Watt JC, Wu CL, Steinman H, Jones SN, Donehower LA. Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis. Oncogene 22(49):7831-7, 2003. PMID: 14586409.
Patient Reviews
CV information above last modified July 15, 2023