
Mariela Blum Murphy, M.D.
Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine
In the News
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Gastrointestinal (GI) Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2003 | Universidad Catolica Santiago de Guayaquil, Guayaquil, ECU, MD, Doctor in Medicine and Surgery |
Postgraduate Training
2008-2011 | Clinical Fellowship, Hematology-Oncology, Baylor College of Medicine, Houston, TX |
2005-2008 | Clinical Residency, Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL |
Board Certifications
2011 | Medical Oncology |
2008 | Internal Medicine |
Experience & Service
Academic Appointments
Associate Professor, Department of Gastrointestinal (GI) Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2018
Institutional Committee Activities
Member, Division Council on Gender Inclusiveness, 2015 - Present
Member, Epic Validation Committee - EHR, 2014 - 2016
Member, Cancer Therapeutics Committee, 2012 - 2014
Consultantships
Consultant, MD Anderson Physicians Network, Houston, TX, 2014 - Present
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Hayashi Y, Xiao L, Suzuki A, Blum MA, Sabloff B, Taketa T, Maru DM, Welsh J, Lin SH, Weston B, Lee JH, Bhutani MS, Hofstetter WL, Swisher SG, Ajani JA. A nomogram associated with high probability of malignant nodes in the surgical specimen after trimodality therapy of patients with esophageal cancer. Eur J Cancer 48(18):3396-404, 2012. e-Pub 2012. PMID: 22853875.
- Blum MA, Suzuki A, Taketa T, Ajani JA. Current therapeutic approaches to localized carcinoma of the esophagus and gastroesophageal junction. Clinical Practice Vol 9(No 4):463-471, 2012.
- Blum MA, Ajani JA. Therapy: Localized gastric cancer-a CLASSIC shift in the paradigm?. Nat Rev Gastroenterol Hepatol 9(4):194-5, 2012. e-Pub 2012. PMID: 22392288.
- Ajani JA, Blum MA, Estrella JS, Das P, Fournier KF. Gastric Cancer: Apples Will Always Be Apples. J Clin Oncol 30(9):1017-8, 2012. e-Pub 2012. PMID: 22331947.
- Suzuki A, Xiao L, Hayashi Y, Blum MA, Welsh JW, Lin SH, Lee JH, Bhutani MS, Weston B, Maru DM, Rice DC, Swisher SG, Hofstetter WL, Erasmus J, Ajani JA. Nomograms for Prognostication of Outcome in Patients with Esophageal and Gastroesophageal Carcinoma Undergoing Definitive Chemoradiotherapy. Oncology 82(2):108-113, 2012. e-Pub 2012. PMID: 22328056.
- Blum MA, Hayashi Y, Ajani JA. Advanced gastroesophageal carcinoma: an update on the current therapeutic landscape. Onkologie 35(4):204-9, 2012. e-Pub 2012. PMID: 22488092.
- Suzuki A, Xiao L, Taketa T, Blum MA, Matamoros A, Chien PL, Mansfield PF, Fournier KF, Weston B, Lee JH, Bhutani MS, Estrella JS, Delclos ME, Krishnan S, Das P, Ajani JA. Localized Gastric Cancer Treated with Chemoradation without Surgery: UTMD Anderson Cancer Center Experience. Oncology 82(6):347-351, 2012. e-Pub 2012. PMID: 22677933.
- Taketa T, Correa AM, Suzuki A, Blum MA, Chien P, Lee JH, Welsh J, Lin SH, Maru DM, Erasmus JJ, Bhutani MS, Weston B, Rice DC, Vaporciyan AA, Hofstetter WL, Swisher SG, Ajani JA. Outcome of Trimodality-Eligible Esophagogastric Cancer Patients Who Declined Surgery after Preoperative Chemoradiation. Oncology 83(5):300-304, 2012. e-Pub 2012. PMID: 22964903.
- Blum MA, Suzuki A, Taketa T, Ajani J. The role of S-1 in the treatment of Gastric Cancer. Gastrointestinal Cancer: Targets and Therapy 1(1):59-67, 2011.
- Blum M, Suzuki A, Ajani JA. A comprehensive review of S-1 in the treatment of advanced gastric adenocarcinoma. Future Oncol 7(6):715-26, 2011. PMID: 21675835.
- Taketa T, Sudo K, Wadhawa R, Blum MM, Ajani JA. Adjuvant Therapy in Gastric Cancer: What Is The Optimal Approach?. Curr Oncol Rep. e-Pub 2013. PMID: 23355076.
- Blum MA, Takashi T, Suzuki A, Ajani JA. Management of localized gastric cancer. J Surg Oncol. e-Pub 2013. PMID: 23303654.
Editorials
- Blum MA, Ajani JA. Chemoradiation: Gastro-oesophageal cancer-is CROSSing over so hard to do?. Nat Rev Clin Oncol 9(9):493-4, 2012. PMID: 22825372.
- Blum Murphy MA, Taketa T, Sudo K, Lee JH, Ajani JA. Surveillance for esophageal cancer: does it make sense?. J Natl Compr Canc Netw 10:1590-92, 2012.
- Blum MA, Ajani JA. Many a mickle makes a muckle. Translating a gastric cancer phenotype into a bigger thing. Onkologie 34(10):499-500, 2011. PMID: 21985847.
Abstracts
- Brian D. Badgwell, Mariela A. Blum, Prajnan Das, Elena Elimova, Paul F. Mansfield, Jaffer A. Ajani. A phase II study of laparoscopic hyperthermic intraperitoneal chemoperfusion (HIPEC) for gastric carcinomatosis or positive cytology. 2016 Gastrointestinal Cancers Symposium, 2016.
- Elena Elimova, Soo-Mi Kim, Xuemei Wang, Yusuke Shimodaira, Bo Hwa Sohn, Heath Devin Skinner, Jeffrey H. Lee, Brian Weston, Manoop S. Bhutani, Bruce D. Minsky, David C. Rice, Jun Eul Hwang, Stephen Swisher, Wayne Lewis Hofstetter, Mariela A. Blum, Dipen M. Maru, Jaffer A. Ajani, Ju-Seog Lee; The University of Texas MD Anderson Cancer Center, Houston, TX; Jeonbuk National University Medical School and Hospital, Jeonju, North Korea; Departments of Systems Biology, Houston, TX; The University of Chicago Medical Center, Chicago, IL. Correlation of pretreatment p63-positive subtype of gastroesophageal adenocarcinoma (GEAC) with pathologic complete response (pathCR) in patients receiving preoperative chemoradiation. 2016 Gastrointestinal Cancers Symposium, 2016.
- Nikolaos Charalampakis, Lianchun Xiao, Elena Elimova, Yusuke Shimodaira, Hironori Shiozaki, Prajnan Das, Aurelio Matamoros, Tara L. Sagebiel, Mariela A. Blum, Jeffrey H. Lee, Manoop S. Bhutani, Brian Weston, Paul F. Mansfield, Bruce D. Minsky, Brian D. Badgwell, Jaffer A. Ajani. Course and predictors of postoperative outcomes in older patients with localized localized gastric adenocarcinoma treated preoperatively. 2016 Gastrointestinal Cancers Symposium, 2016.
- Naruhiko Ikoma, Elena Elimova, Mariela A. Blum, Jaffer A. Ajani, Y. Sabrina Chiang, Keith F. Fournier, Paul F. Mansfield, Brian D. Badgwell; The University of Texas MD Anderson Cancer Center, Houston, TX. Preoperative accuracy of gastric cancer staging in patient selection for neoadjuvant therapy. 2016 Gastrointestinal Cancers Symposium, 2016.
- Naruhiko Ikoma, Elena Elimova, Mariela A. Blum, Jaffer A. Ajani, Y. Sabrina Chiang, Keith F. Fournier, Paul F. Mansfield, Brian D. Badgwell; The University of Texas MD Anderson Cancer Center, Houston, TX; The University of Texas MD Anderson Cancer Center. Risk Factors for Survival in Early T Stage Gastric Cancer. 2016 Gastrointestinal Cancers Symposium, 2016.
- Naruhiko Ikoma, Elena Elimova, Mariela A. Blum, Jaffer A. Ajani, Y. Sabrina Chiang, Keith F. Fournier, Paul F. Mansfield, Brian D. Badgwell; The University of Texas MD Anderson Cancer Center, Houston, TX; The University of Texas MD Anderson Cancer Center, Missouri City, TX. Staging Laparoscopy with Cytology Analysis in Gastric Cancer. 2016 Gastrointestinal Cancers Symposium, 2016.
- Humaid Obaid Al-Shamsi, Jane Rogers, Jeannette Elizabeth Mares, Mariela A. Blum, Ibrahim Dahbour, Yazan Fahmawi, Quan Lin, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX. Continuation of trastuzumab beyond disease progression in patient with metastatic gastric cancer: A retrospective analysis of 25 cases- The MD Anderson experience. 2016 ASCO Annual Meeting, 2016.
- Yusuke Shimodaira, Rebecca Slack, Hsiang-Chun Chen, Manoop S. Bhutani, Jeffrey H Lee, Brian Weston, Elena Elimova, Quan Lin, Kazuto Harada, Fatemeh G Amlashi, Dilsa Mizrak, Mariela A. Blum, Jack A. Roth, Stephen Swisher, Heath Devin Skinner, Wayne Lewis Hofstetter, Ritsuko Komaki, Garrett L. Walsh, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX; The University of Texas MD Anderson Cancer Center Department of Gastrointestinal Medical Oncology, Houston, TX; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX. Influence of induction chemotherapy (IC) in trimodality-eligible esophageal cancer patients: Secondary analysis of a randomized trial. 2016 ASCO Annual Meeting, 2016.
- Mariela A. Blum, Lianchun Xiao, Arlene M. Correa, Roopma Wadhwa, Elena Elimova, Heath Devin Skinner, Ritsuko Komaki, Jeffrey H. Lee, Manoop S. Bhutani, Brian Weston, Zhongxing X. Liao, David C. Rice, Stephen Swisher, Wayne Lewis Hofstetter, Jaffer A. Ajani. Analysis of patients with esophageal cancer following trimodality therapy: Pathological complete remission (PathCR) versus non-PathCR. 2015 ASCO Annual Meeting, 2015.
- Elena Elimova, Xuemei Wang, Wei Qiao, Kazuki Sudo, Roopma Wadhwa, Hironori Shiozaki, Venkatram Planjery, Nikolaos Charalampakis, Heath Devin Skinner, Jeffrey H. Lee, Brian Weston, Manoop S. Bhutani, Ritsuko Komaki, David C. Rice, Stephen Swisher, Mariela A. Blum, Dipen M. Maru, Wayne Lewis Hofstetter, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX. Actionable locoregional failures (LRFs) after therapy of localized esophageal carcinoma (LEC): Surveillance strategies and their benefits. 2015 Gastrointestinal Cancers Symposium, 2015.
- Hironori Shiozaki, Elena Elimova, Rebecca Slack, Hsiang-Chun Chen, Gregg A Staerkel, Nour Sneige, Venkatram Planjery, Nikolaos Charalampakis, Roopma Wadhwa, Kazuki Sudo, Aurelio Matamoros, Jeffrey H. Lee, Brian Weston, Manoop S. Bhutani, Mariela A. Blum, Jeannelyn Estrella, Prajnan Das, Paul F. Mansfield, Brian D. Badgwell, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX; Houston Methodist Hospital, Houston, TX. Prognosis of gastric cancer (GC) patients with positive peritoneal cytology. 2015 Gastrointestinal Cancers Symposium, 2015.
- Yusuke Shimodaira, Elena Elimova, Hironori Shiozaki, Roopma Wadhwa, Nikolaos Charalampakis, Venkatram Planjery, Mariela A. Blum, Quynh Nguyen, Heath Devin Skinner, Rebecca Slack, Dipen M. Maru, Wayne Lewis Hofstetter, Brian Weston, Manoop S. Bhutani, Jeffrey H. Lee, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX. Accuracy of EUS-FNA for distant regional lymph nodes in the initial staging of esophageal cancer (EC). 2015 ASCO Annual Meeting, 2015.
- Nikolaos Charalampakis, Graciela M. Nogueras-Gonzalez, Elena Elimova, Roopma Wadhwa, Hironori Shiozaki, Yusuke Shimodaira, Mariela A. Blum, Jane Elizabeth Rogers, Jeana Garris, Aurelio Matamoros, Tara L. Sagebiel, Prajnan Das, Jeannelyn Estrella, Brian D. Badgwell, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX; Department of Pharmacy Clinical Programs, The University of Texas MD Anderson Cancer Center, Houston, TX.. Signet ring cell (SRC) histology of localized gastric adenocarcinoma (LGAC) to predict response to preoperative chemoradiation. 2015 ASCO Annual Meeting, 2015.
- Kazuki Sudo, Xuemei Wang, Roopma Wadhwa, Hironori Shiozaki, Wayne Lewis Hofstetter, David C. Rice, Jeffrey H. Lee, Manoop S. Bhutani, Brian Weston, Heath D. Skinner, Ritsuko Komaki, Dipen M. Maru, Mariela A. Blum, Jaffer A. Ajani; The University of Texas MD Anderson eancer Center, Houston, TX. Clinical parameters’ model for predicting distant metastasis (DM) following definitive therapy in patients with localized esophageal and esophagogastric junction (E-EGJ). 2014 Gastrointestinal Cancers Symposium, 2014.
- Roopma Wadhwa, Xuemei Wang, Julie Izzo, Heath D. Skinner, Jeffrey H. Lee, Manoop S. Bhutani, Brian Weston, William A. Ross, Wayne Lewis Hofstetter, Dipen M. Maru, David C. Rice, Kazuki Sudo, Hironori Shiozaki, Mariela A. Blum, Qiongrong Chen, Jiankang Jin, Shumei Song, Veera Baladandayuthapani, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX. Correlation of pretreatment nuclear GLI-1 labeling indices (LIs) with initial SUV (iSUV) in esophageal cancer (EC) patients undergoing trimodality therapy (TMT): A potential pathway to esophageal preservation. 2014 Gatrointestinal Cancers Symposium, 2014.
- Hironori Shiozaki, Kazuki Sudo, Roopma Wadhwa, Wayne Lewis Hofstetter, Heath D. Skinner, Ritsuko Komaki, Jeffrey H. Lee, Brian Weston, Manoop S. Bhutani, Dipen M. Maru, Mariela A. Blum, Jaffer A. Ajani; The University of Texas MD Anderson Cancer Center, Houston, TX. Distribution and timing of distant metastasis (DM) after definitive therapy for patients with esophageal and esophagastric junction (E-EGJ) cancer. 2014 Gastrointestinal Cancers Symposium, 2014.
- Elena Elimova, Roopma Wadhwa, Kazuki Sudo, Hironori Shiozaki, Rebecca Slack, Hsiang-Chun Chen, Brian D. Badgwell, Aurelio Matamoros, Jeffrey H. Lee, Brian Weston, Manoop S. Bhutani, Mariela A. Blum, Jeannelyn Estrella, Prajnan Das, Jaffer A. Ajani; MD Anderson Cancer Center, Houston, TX; The University of Texas MD Anderson Cancer Center, Houston, TX. A phase II study of preoperative chemotherapy and chemoradiation for localized gastric and gastroesophageal junction adenocarcinoma (LGCA). 2014 ASCO Annual Meeting, 2014.
- Taketa T, Correa AM, Suzuki A, Blum MA, Lee JE, Welsh J, Lin SH, Maru D, Erasmus JJ, Bhutani MS, Weston B, Rice DC, Swisher S, Wayne Lewis Hofstetter WL, Ajani JA. Outcome of trimodality-eligible esophagogastric cancer (EC) patients who declined surgery after preoperative chemoradiation. J Clin Oncol 4(6), 2012.
- Suzuki A, Xiao L, Hayashi Y, Blum MA, Welsh J, Lin SH, Lee JH, Bhutani MS, Weston B, Maru D, Rice DC, Hofstetter WL, Erasmus JJ, Swisher S, Ajani JA. Nomograms for prognostication of patients with esophageal and gastroesophageal carcinoma undergoing definitive chemoradiotherapy. J Clin Oncol 4(82), 2012.
- Lara M Paraskos, Mariela A. Blum, Maricer Escalon, Annapoorna Ferrell, Erin Kobetz, and Joseph Rosenblatt. Defining Outcomes in Hispanic Aggressive Non-Hodgkin Lymphoma Patients. Blood 114(4542), 2009.
Book Chapters
- Blum M, and Lynch G. Neuroendocrine Tumors. In: Tumor Board Review: Guidelines and Case Reviews in Clinical Oncology, 2011.
Letters to the Editor
- Ajani JA, Blum MA, Welsh J, Hofstetter WL, Swisher SG. Celebrate or calibrate? We say calibrate. J Clin Oncol 29: 2732; author reply 2732-3, 2011.
Grant & Contract Support
Title: | Dual pathway inhibition in biomarker enriched patients with advanced GE cancer |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |