Marites Pasuelo Melancon, Ph.D.
Department of Interventional Radiology, Division of Diagnostic Imaging
About Dr. Melancon
Dr. Marites Melancon is an Assistant Professor in the Department of Interventional Radiology at The University of Texas, M.D. Anderson Cancer Center. Dr. Melancon earned her BS degree in chemistry from the University of San Carlos (Cebu, Philippines) in 1994 and her MS degree in chemistry at Ateneo de Manila University (Manila, Philippines) in 2000. She received her PhD in Biomedical Science at The University of Texas-Health Science Center at Houston Graduate School of Biomedical Science in December 2007. She then trained in the Department of Imaging Physics as an Odyssey Fellow from 2008-2010 and was promoted to Instructor in 2011. She joined Interventional Radiology in 2012 working on the synthesis, characterization and in vivo evaluation of multimodality and multifunctional nanoparticles for image-guided therapy. She is also currently working on radiopaque absorbable medical devices. Her main goal is to apply the "seek and treat" strategy in the development of targeted imaging/therapeutic agents that will eventually be translated to the clinic to improve the management of cancer through early tumor detection and individualized therapy.
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Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Interventional Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, Odyssey and Summer Experience Programs, Division of Education and Training, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Division of Graduate School of Biomedical Science, The University of Texas Health Science Center, Houston, TX
Research Interests
Nanotechnology, absorbable medical device, drug delivery, image-guided therapy, molecular imaging and ablation therapies
Education & Training
Degree-Granting Education
| 2007 | The University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA, PHD, Biomedical Science |
| 2000 | Ateneo de Manila University, Manila, PHL, MS, Chemistry |
| 1994 | University of San Carlos, Cebu, PHL, BS, Chemistry |
Experience & Service
Academic Appointments
Assistant Professor, Department of Interventional Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2018
Instructor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2012
Instructor, Department of Chemistry, Ateneo de Manila University, Manila, 2000 - 2002
Institutional Committee Activities
Member, Institutional Research Grant, 2018 - Present
Member, Postdoctoral Advisory Committee, 2016 - Present
Ex Officio Member, Graduate Education Committee, 2016 - Present
Member, Education Council, 2016 - Present
Chair, Odyssey Program, 2015 - 2016
Member, Faculty Academic Review Committee (FARC), 2014 - 2017
Vice Chair, Odyssey Program, 2014 - 2015
Member, Odyssey Program, 2013 - 2014
IR Faculty Representative, DI Research Functional Committee, 2013 - 2015
Honors & Awards
| 2017 | Carl Storm Underrepresented Minority (CSURM) Fellowship, Gordon Research Conference |
| 2016 | Finalist Robert Chamberlain Distinguished Mentor Award, MD Anderson Postdoc Association |
| 2016 | Early Career Reviewer, NIH Center for Scientific Review (NOIT) |
| 2015 | Council on Cardiovascular Radiology & Intervention Minority Travel Stipend, American Heart Association |
| 2014 | Balik Scientist Awardee, Department of Science and Technology, Manila, Philippines |
| 2010 | Trainee Excellence Award, The University of Texas MD Anderson Cancer Center |
| 2010 | Student Travel Award, World Molecular Imaging Congress, Kyoto, Japan |
| 2009 | Odyssey Fellowship, University of Texas MD Anderson Cancer Center |
| 2009 | Student Travel Award, World Molecular Imaging Congress, Montreal, Canada |
| 2008 | Student Travel Award, World Molecular Imaging Congress, Nice, France |
| 2000 | Dean’s Award for Best Graduate Research, Ateneo de Manila University, Philippines |
| 1997 | Department of Science and Technology- Philippine Council for Advanced Science and Technology Research and Development (DOST-PCASTRD) Scholarship, Philippines |
| 1994 | Cum Laude, University of San Carlos, Cebu Philippines |
Selected Publications
Peer-Reviewed Articles
- Damasco JA, Huang SY, Perez JVD, Manongdo JAT, Dixon KA, Williams ML, Jacobsen MC, Barbosa R, Canlas GM, Chintalapani G, Melancon AD, Layman RR, Fowlkes NW, Whitley EM, Melancon MP. Bismuth Nanoparticle and Polyhydroxybutyrate Coatings Enhance the Radiopacity of Absorbable Inferior Vena Cava Filters for Fluoroscopy-Guided Placement and Longitudinal Computed Tomography Monitoring in Pigs. ACS Biomater Sci Eng 8(4):1676-1685, 2022. e-Pub 2022. PMID: 35343679.
- Vardaki I, Corn P, Gentile E , Song JH, Madan N, Hoang A, Parikh N, Guerra L, Lee Y-C, Lin S-C, Yu G, Santos E, Melancon MP, Troncoso P, Navone N, Gallick GE, Efstathiou E, Subudhi SK, Lin S-H, Logothetis CJ, Panaretakis T. Radium 223 treatment increase immune checkpoint expression in extracellular vesicles from the metastatic prostate cancer bone microenvironment. Clinical Cancer Research 27(11):3253-3264, 2021. PMID: 33753455.
- Rojo RD, Perez JV, Damasco JA, Yu G, Lin S-C, Heralde FM, Santos EB, Lin S-H, and Melancon MP. Combinatorial effect of radium-223 and irreversible electroporation on prostate cancer bone metastasis in mice. International Journal of Hyperthermia 38(1):650-662, 2021. PMID: 33882773.
- Melancon MP, Yevich S, Avritscher R, Swigost A, Lu L, Tian L, Damasco J, Dixon K, Munoz N, Dong L, Liu D, Tam AL. A Novel Lipiodol-Irinotecan Nanoemulsion for Intravascular Administration: Pharmacokinetics and Biodistribution in the Normal and Tumor Bearing Rat Liver. Drug Delivery 28(1):240-251, 2021. e-Pub 2020. PMID: 33501859.
- Hagaman DE, Damasco JA, Perez JD, Rojo RD, Melancon MP. Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis. Molecules 26(2):384, 2021. e-Pub 2021. PMID: 33450939.
- Perez JD, Singhana S, Damasco J, Lu L, Behlau P, Rojo R, Whitley E, Heralde F, Melancon A, Huang S, Melancon MP. Radiopaque scaffolds based on electrospun iodixanol/polycaprolactone nanofibrous composites. Materialia 14:100874, 2020.
- Perez JA, Jacobsen M, Damasco J, Huang S, Melancon A, Layman R, Melancon MP. Optimization of the differentiation and quantification of high Z nanoparticles incorporated in medical devices for CT-guided interventions. Medical Physics 48(1):300-312, 2020. e-Pub 2020.
- Damasco JA, Ravi S, Perez JD, Hagaman DE, Melancon MP. Understanding Nanoparticle Toxicity to Direct a Safe-by-Design Approach in Cancer Nanomedicine. Nanomaterials (Basel) 10(11), 2020. e-Pub 2020. PMID: 33147800.
- Huang SY, Damasco JA, Tian L, Lu L, Dixon K, Williams M, Eggers M, Melancon AD, Layman RR, Whitley EM, Melancon MP. In vivo performance of gold nanoparticle-loaded absorbable inferior vena cava filters in a swine model. Biomaterials Science(14), 2020. e-Pub 2020. PMID: 32558854.
- Sheth RA, Wen X, Li J, Melancon MP, Ji X, Wang A, Hsiao C, Chow D, Whitley E, Li C and Gupta S. Doxorubicin‑loaded hollow gold nanospheres for dual photothermal ablation and chemoembolization therapy. Cancer Nanotechnology 11(6):1635, 2020. e-Pub 2020.
- Avritscher R, Jo N, Polak U, Cortes AC, Nishiofuku H, Odisio BC, Takaki H, Tam AL, |Melancon MP, Yevich S, Qayyum A, Kaseb A, Kichikawa K, Gupta S, Goldberg SN, Chang SH. Hepatic arterial bland embolization increases Th17 cell infiltration in a syngeneic rat model of hepatocellular carcinoma. Cardiovasc Intervent Radiol 43(2):311-321, 2020. e-Pub 2019. PMID: 31591689.
- Lin M, Paolillo V, Ta RT, Damasco J, Rojo RD, Carl JC, Melancon MP, Ravizzini GC, Le DB, Santos EB. Fully Automated Preparation of 68Ga-PSMA-11 at Curie Level Quantity Using Cyclotron-Produced 68Ga for Clinical Applications. Appl Radiat Isot 155:108936, 2020. e-Pub 2019. PMID: 31655351.
- Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, Melancon MP, Gupta S, Shen B, Peng W, Li C. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nat Commun 10(899):1-14, 2019. e-Pub 2019. PMID: 30796212.
- Tian L, Qiao Y, Lee P, Wang L, Chang A, Ravi S, Rogers TA, Lu L, Singhana B, Zhao J, Melancon MP. Antitumor efficacy of liposome-encapsulated NVP-BEZ 235 in combination with irreversible electroporation. Drug Deliv 25(1):668-678, 2018. e-Pub 2018. PMID: 29482386.
- Tian L, Lu L, Feng J, Melancon MP. Radiopaque nano and polymeric materials for atherosclerosis imaging, embolisation and other catheterization procedures. Acta Pharm Sin B 8(3):360-370, 2018. e-Pub 2018. PMID: 29881675.
- Qiao Y, Gumin J, MacLellan CJ, Gao F, Bouchard R, Lang FF, Stafford RJ, Melancon MP. Magnetic resonance and photoacoustic imaging for treatment planning of brain tumor mediated by mesenchymal stem cell-labeled with multifunctional nanoparticle. Nanotechnology 29(16):165101, 2018. e-Pub 2018. PMID: 29438105.
- Tian L, Lee P, Singhana B, Chen A, Qiao Y, Lu L, Martinez J, Tasciotti E, Jacobsen MC, Melancon A, McArthur M, Eggers M, Huang S, Melancon MP. In vivo imaging of radiopaque resorbable inferior vena cava filter infused with gold nanoparticles. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 10576(105762S), 2018. e-Pub 2018.
- Cao Q, Yan X, Chen K, Huang Q, Melancon MP, Lopez G, Cheng Z, Li C. Macrophages as a Potential Tumor-Microenvironment Target for Noninvasive Imaging of Early Response to Anticancer Therapy. Biomaterials 152:63-76, 2018. e-Pub 2017. PMID: 29111494.
- Melancon MP, Appleton Figueira T, Fuentes DT, Tian L, Qiao Y, Gu J, Gagea M, Ensor JE, Muñoz NM, Maldonado KL, Dixon K, McWatters A, Mitchell J, McArthur M, Gupta S, Tam AL. Development of an Electroporation and Nanoparticle-based Therapeutic Platform for Bone Metastases. Radiology 286(1):161721, 2018. e-Pub 2017. PMID: 28825892.
- Huang SY, Eggers M, McArthur MJ, Dixon KA, McWatters A, Dria S, Hill LR, Melancon MP, Steele JR, Wallace MJ. Safety and Efficacy of an Absorbable Filter in the Inferior Vena Cava to Prevent Pulmonary Embolism in Swine. Radiology 285(3):161880, 2017. e-Pub 2017. PMID: 28708470.
- Tian L, Lee P, Singhana B, Chen A, Qiao Y, Lu L, Martinez JO, Tasciotti E, Melancon A, Huang S, Eggers M, Melancon MP. Radiopaque Resorbable Inferior Vena Cava Filter Infused with Gold Nanoparticles. Sci Rep 7(1):2147, 2017. e-Pub 2017. PMID: 28526874.
- Tian L, Chang A, Melancon MP. Exploring gold nanoparticle interactions with proteins and the tumor microenvironment in biological systems. Transl Cancer Res 6(Suppl 2):S309-S312, 2017. e-Pub 2017. PMID: 28690978.
- Zhou M, Melancon MP, Stafford RJ, Li J, Nick AM, Tian M, Sood AK, Li C. Precision Nanomedicine Using Dual Positron Emission Tomography and Magnetic Resonance Temperature Imaging-Guided Photothermal Therapy. J Nucl Med 57(11):1778-1783, 2016. e-Pub 2016. PMID: 27283932.
- Tam AL, Melancon MP, Abdelsalam M, Figueira TA, Dixon K, McWatters A, Zhou M, Huang Q, Mawlawi O, Dunner K, Li C, Gupta S. Imaging Intratumoral Nanoparticle Uptake after Combining Nanoembolization with Various Ablative Therapies in Hepatic VX2 Rabbit Tumors. J Biomed Nanotechnol 12(2):296-307, 2016. PMID: 27305763.
- Hosoya H, Dobroff AS, Driessen WH, Cristini V, Brinker LM, Staquicini FI, Cardó-Vila M, D'Angelo S, Ferrara F, Proneth B, Lin YS, Dunphy DR, Dogra P, Melancon MP, Stafford RJ, Miyazono K, Gelovani JG, Kataoka K, Brinker CJ, Sidman RL, Arap W, Pasqualini R. Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release. Proc Natl Acad Sci U S A 113(7):1877-82, 2016. e-Pub 2016. PMID: 26839407.
- Tian L, Lu L, Qiao Y, Ravi S, Salatan F, Melancon MP. Stimuli-responsive gold nanoparticles for cancer diagnosis and therapy. J Funct Biomater 7(3), 2016. e-Pub 2016. PMID: 27455336.
- Zhao J, Lee P, Wallace MJ, Melancon MP. Gold Nanoparticles in Cancer Therapy: Efficacy, Biodistribution, and Toxicity. Curr Pharm Des 21(29):4240-51, 2015. e-Pub 2015. PMID: 26323426.
- Zhao J, Qiao J, Zhou M, Gupta S, Li C, Melancon MP. Anti-tumor Efficacy Study using Irreversible Electroporation and Doxorubicin-loaded Polymeric Micelles. ACS Macro Lett 4(10):1081-1084, 2015. e-Pub 2015. PMID: 28529822.
- Zhao J, Melancon MP, Zhou M. Nanoparticle Formulation to Improve the Efficacy of Radiation Therapy Against Radiation-Resistant Leukemia. EBioMedicine 2(6):486, 2015. e-Pub 2015. PMID: 26288809.
- Mitcham T, Dextraze K, Taghavi H, Melancon M, Bouchard R. Photoacoustic imaging driven by an interstitial irradiation source. Photoacoustics 3(2):45-54, 2015. e-Pub 2015. PMID: 26236640.
- Singhana B, Chen A, Slattery P, Yazdi IK, Qiao Y, Tasciotti E, Wallace M, Huang S, Eggers M, Melancon MP. Infusion of Iodine-Based Contrast Agents into Poly(p-dioxanone) as a Radiopaque Resorbable IVC Filter. J Mater Sci Mater Med 26(3):124, 2015. e-Pub 2015. PMID: 25690619.
- Tam AL, Melancon MP, Ensor J, Liu Y, Dixon K, McWatters A, Gupta S. Rabbit Hepatic Arterial Anatomy Variations: Implications on Experimental Design. Acta Radiol 55(10):1226-33, 2014. e-Pub 2013. PMID: 24292899.
- Zhao J, Vykoukal J, Abdelsalam M, Recio-Boiles A, Huang Q, Qiao Y, Singhana B, Wallace M, Avritscher R, Melancon MP. Stem cell-mediated delivery of SPIO-loaded gold nanoparticles for the theranosis of liver injury and hepatocellular carcinoma. Nanotechnology 25(40):405101, 2014. e-Pub 2014. PMID: 25211057.
- Zhao J, Wallace M, Melancon MP. Cancer Theranostics with Gold Nanoshells. Nanomedicine (Lond) 9(13):2041-57, 2014. PMID: 25343352.
- Singhana B, Slattery P, Chen A, Wallace MJ, Melancon MP. Light-Activatable Gold Nanoshells for Drug Delivery Applications. AAPS PharmSciTech 15(3):741-52, 2014. e-Pub 2014. PMID: 24550102.
- Melancon MP, Zhou M, Zhang R, Xiong C, Allen P, Wen X, Huang Q, Wallace M, Myers JN, Stafford RJ, Liang D, Ellington AD, Li C. Selective Uptake and Imaging of Aptamer- and Antibody-Conjugated Hollow Nanospheres Targeted to Epidermal Growth Factor Receptors Overexpressed in Head and Neck Cancer. ACS Nano 8(5):4532-8, 2014. e-Pub 2014. PMID: 24754567.
- Zhou M, Singhana B, Liu Y, Huang Q, Mitcham T, Wallace MJ, Stafford RJ, Bouchard RR, Melancon MP. Photoacoustic- and Magnetic Resonance-Guided Photothermal Therapy and Tumor Vasculature Visualization Using Theranostic Magnetic Gold Nanoshells. J Biomed Nanotechnol 11(8):1385-1400, 2014. PMID: 26295144.
- Lee HJ, Liu Y, Zhao J, Zhou M, Bouchard RR, Mitcham T, Wallace MJ, Stafford RJ, Li C, Gupta S, Melancon MP. In vitro and in vivo mapping of drug release after laser ablation thermal therapy with Doxorubicin-loaded hollow gold nanoshells using fluorescence and photoacoustic imaging. J Control Release 172(1):152-158, 2013. e-Pub 2013. PMID: 23920038.
- Melancon MP, Stafford RJ, Li C. Challenges to effective cancer nanotheranostics. J Control Release 164(2):177-82, 2012. e-Pub 2012. PMID: 22906841.
- You J, Zhang R, Xiong C, Zhong M, Melancon MP, Gupta S, Nick AM, Sood AK, Li C. Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res 72(18):4777-4786, 2012. e-Pub 2012. PMID: 22865457.
- Zhang G, Zhang R, Melancon MP, Wong K, You J, Huang Q, Bankson J, Liang D, Li C. The degradation and clearance of Poly(N-hydroxypropyl-L-glutamine)-DTPA-Gd as a blood pool MRI contrast agent. Biomaterials 33(21):5376-83, 2012. e-Pub 2012. PMID: 22541356.
- Melancon MP, Elliott AM, Shetty A, Huang Q, Stafford RJ, Li C. Near-infrared light modulated photothermal effect increases vascular perfusion and enhances polymeric drug delivery. J Control Release 156(2):265-72, 2011. e-Pub 2011. PMID: 21763373.
- Melancon MP, Zhou M, Li C. Cancer Theranostics with Near-Infrared Light-Activatable Multimodal Nanoparticles. Acc Chem Res 44(10):947-956, 2011. e-Pub 2011. PMID: 21848277.
- Melancon MP, Lu W, Zhong M, Zhou M, Liang G, Elliott AM, Hazle JD, Myers JN, Li C, Stafford RJ. Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer. Biomaterials 32(30):7600-8, 2011. e-Pub 2011. PMID: 21745689.
- Lu W, Melancon MP, Xiong C, Huang Q, Elliott A, Song S, Zhang R, Flores LG, Gelovani JG, Wang LV, Ku G, Stafford RJ, Li C. Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma. Cancer Res 71(19):6116-21, 2011. e-Pub 2011. PMID: 21856744.
- Melancon MP, Elliott A, Ji X, Shetty A, Yang Z, Tian M, Taylor B, Stafford RJ, Li C. Theranostics with multifunctional magnetic gold nanoshells: photothermal therapy and t2* magnetic resonance imaging. Invest Radiol 46(2):132-40, 2011. PMID: 21150791.
- Melancon MP, Li C. Multifunctional synthetic polymer-based therapeutic and diagnostic agents. Mol Imaging 10(1):28-42, 2011. PMID: 21303613.
- Zhou M, Zhang R, Huang M, Lu W, Song S, Melancon MP, Tian M, Liang D, Li C. A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy. J Am Chem Soc 132(43):15351-8, 2010. PMID: 20942456.
- Melancon MP, Lu W, Huang Q, Thapa P, Zhou D, Ng C, Li C. Targeted imaging of tumor-associated M2 macrophages using a macromolecular contrast agent PG-Gd-NIR813. Biomaterials 31(25):6567-73, 2010. PMID: 20537382.
- Melancon MP, Lu W, Li C. Gold-Based Magneto/Optical Nanostructures: Challenges for In Vivo Applications in Cancer Diagnostics and Therapy. Mater Res Bull 34(6):415-421, 2009. PMID: 20582234.
- Melancon MP, Lu W, Yang Z, Zhang R, Cheng Z, Elliot AM, Stafford J, Olson T, Zhang JZ, Li C. In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy. Mol Cancer Ther 7(6):1730-9, 2008. PMID: 18566244.
- Melancon MP, Wang Y, Wen X, Bankson JA, Stephens LC, Jasser S, Gelovani JG, Myers JN, Li C. Development of a macromolecular dual-modality MR-optical imaging for sentinel lymph node mapping. Invest Radiol 42(8):569-78, 2007. PMID: 17620940.
- Melancon MP, Wang W, Wang Y, Shao R, Ji X, Gelovani JG, Li C. A novel method for imaging in vivo degradation of poly(L-glutamic acid), a biodegradable drug carrier. Pharm Res 24(6):1217-24, 2007. e-Pub 2007. PMID: 17377742.
- Wang W, Wu Q, Pasuelo MJ, McMurray JS, Li C. Probing for integrin alpha v beta3 binding of RGD peptides using fluorescence polarization. Bioconjug Chem 16(3):729-34, 2005. PMID: 15898744.
- Wen X, Cao X, Pasuelo MJ, Wendt R, Li C. Polymeric radiotracers in nuclear imaging. Curr Drug Deliv 1(4):377-84, 2004. PMID: 16305399.
- Tansey W, Ke S, Cao XY, Pasuelo MJ, Wallace S, Li C. Synthesis and characterization of branched poly(L-glutamic acid) as a biodegradable drug carrier. J Control Release 94(1):39-51, 2004. PMID: 14684270.
- Pasuelo MJ , Dayrit FM. Development if quality assurance methods for medicinal plants using gas chromatography analysis. Kimika 17:5-11, 2001.
Abstracts
- Melancon A, Jacobsen M, Salatan F, Jones A, Cody D, Nute J, Pasuelo MJ. SU-F-207-07: Dual-Energy Computed Tomography Detection Limit of Various Radiopaque Contrast Agents That Can Be Infused Within Absorbable Inferior Vena Cava Filters. Med Phys 42(6):3543, 2015. PMID: 26128553.
Book Chapters
- Singhana B, Slattery P, Melancon MP. Targeted Gold Nanoshells. In: Applications of Nanoscience in Photomedicine. Woodhead Publishing Limited, 2015.
- Lu W, Melancon MP, Li C. Theranostic Applications of Gold Core-Shell Structured Nanoparticles. In: Nanoplatform-based Molecular Imaging. John Wiley & Sons Publishing: Hoboken, NJ, 683-708, 2011.
- Melancon MP, Wen X, Zhang G, Li C. Multi-functional multi-modality cancer imaging with synthetic polymers. In: Nanoimaging. Pan Stanford Publishing Pte Ltd: Singapore, 2010.
- Melancon MP, Li C. Core-shell magnetic nanomaterials for medical diagnosis and therapy. In: Magnetic Nanomaterials. Wiley-VCH: Weinheim, Germany, 259-290, 2009.
Grant & Contract Support
| Title: | Targeted Nanoshell-based Agent for MRI-Guided Thermal Ablation of Recurrent Head and Neck Cancer |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator - CDA |
| Title: | MRI- Guided Thermal Ablation Mediated by Multifunctional Gold-Based Nanoshells |
| Funding Source: | Odyssey Program |
| Role: | Principal Investigator |
| Title: | Molecular Imaging Strategy for Treatment Planning of Brain Tumor Mediated by Stem Cells Labeled with Multifunctional Nanoparticle |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator - CDA |
| Title: | Developing an electroporation and nanoparticle-based therapeutic platform for bone metastases: evaluation of local delivery strategies to optimize intratumoral nanoparticle uptake |
| Funding Source: | Radiological Society of North America (RSNA) |
| Role: | Collaborator |
| Title: | Visual and Functional Characterization of Nanopore Formation after Irreversible Electroporation (IRE) in the Porcine Vertebral Body |
| Funding Source: | Society of Interventional Radiology Foundation |
| Role: | Collaborator |
| Title: | Development of Theranostic Agents for Cancer |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Principal Investigator |
| Title: | Radiopaque enhancement of absorbable IVC filters mediated by gold nano particles using dual-energy computed tomography |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | Principal Investigator |
| Title: | Radiopaque absorbable inferior vena cava filter for dual-energy computed tomography |
| Funding Source: | American Heart Association |
| Role: | Principal Investigator |
| Title: | Nanoparticle-Infused Radiopaque Absorbable Medical Device |
| Funding Source: | NIH/NHLBI |
| Role: | Principal Investigator |
| Title: | Nanoparticle-Infused Radiopaque Absorbable Medical Device |
| Funding Source: | NIH/NHLBI |
| Role: | Principal Investigator |
| Title: | Drug Release and Pharmacokinetic after chemoembolization using Irinotican (IRI)- loaded lipiodol Emulsions and drug eluting beads in a rat tumor model |
| Funding Source: | Guerbet |
| Role: | Co-Investigator |
| Title: | Transportal Irinotecan Chemoembolization using a Lipiodol Nano-emulsion (TICL) for the Treatment of Colorectal Liver Metastases in Rat |
| Funding Source: | Radiological Society of North America (RSNA) |
| Role: | Collaborator |
| Title: | Bone-specific delivery of palovarotene for prostate cancer bone metastasis treatment |
| Funding Source: | MDACC |
| Role: | Principal Investigator |
| Title: | Endothelial-to-osteoblast transition in prostate cancer bone metastasis |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Title: | Biodegradable Radiopaque Polymeric Scaffolds Loaded with Mesenchymal Stem Cells for Image-Guided Arteriovenous Fistula Maturation and Long-Term Patency |
| Funding Source: | NIH/NHLBI |
| Role: | Principal Investigator |
| Title: | Development of a resorbable radiopaque rosuvastatin-eluting polymer to improve rates of arteriovenous fistula maturation and long-term patency for patients on hemodialysis |
| Funding Source: | Society for Interventional Radiology |
| Role: | Co-Investigator |
| Title: | Center for Advanced Biomedical Imaging Pilot Project Program Grant |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Principal Investigator |
| Title: | Nanoparticle-Infused Radiopaque Absorbable Medical Device |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Principal Investigator |