Maurizio Chiriva Internati, DBSc, PhDs

Peer-Reviewed Articles

1. Hegazi MAAA, Pasqualini F, Taverna G, Bresalier RS, Chiriva-Internati M, Grizzi F. Investigating the Spatial Distribution of Proliferating Cells in Primary Ovarian Cancers. Discov Med 36(182):632-645, 2024. e-Pub 2024. PMID: 38531804.
2. Grizzi F, Chiriva-Internati M, Miranda E, Zaharie R, Hajjar NA, Zaharie F, Del Arco CD, Fernandez-Acenero MJ, Bresalier RS, Mois E. Sperm protein antigen 17 and Sperm flagellar 1 cancer testis antigens are expressed in a rare case of ciliated foregut cyst of the common hepatic duct. Pathol Res Pract 247:154546, 2023. e-Pub 2023. PMID: 37224658.
3. Mirandola L, Chiriva-Internati M, Bresalier R, Piccotti L, Grizzi F, Marincola FM. A novel method for efficient generation of antigen-specific effector T-cells using dendritic cells transduced with recombinant adeno-associated virus and p38 kinase blockade. J Transl Med 17(1):424, 2019. e-Pub 2019. PMID: 31878933.
4. Grizzi F, Fiorino S, Qehajaj D, Fornelli A, Russo C, de Biase D, Masetti M, Mastrangelo L, Zanello M, Lombardi R, Domanico A, Accogli E, Tura A, Mirandola L, Chiriva-Internati M, Bresalier RS, Jovine E, Leandri P, Di Tommaso L. Computer-aided assessment of the extra-cellular matrix during pancreatic carcinogenesis: a pilot study. J Transl Med 17(1):61, 2019. e-Pub 2019. PMID: 30819202.
5. Mattila JP, Mirandola L, Chiriva-Internati M. Development of a M cell-targeted microparticulate platform, BSK02, for oral immunization against the ovarian cancer antigen, sperm protein 17. J Biomed Mater Res B Appl Biomater 107(1):29-36, 2019. e-Pub 2019. PMID: 29504239.
6. Brunette LL, Mhawech-Fauceglia PY, Ji L, Skeate JG, Brand HE, Lawrenson K, Walia S, Chiriva-Internati M, Groshen S, Roman LD, Kast WM, Da Silva DM. Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study. BMC Cancer 18(1):970, 2018. e-Pub 2018. PMID: 30309325.
7. Ruvolo PP, Ruvolo VR, Burks JK, Qiu Y, Wang RY, Shpall EJ, Mirandola L, Hail N Jr, Zeng Z, McQueen T, Daver N, Post SM, Chiriva-Internati M, Kornblau SM, Andreeff M. Role of MSC-derived galectin 3 in the AML microenvironment. Biochim Biophys Acta Mol Cell Res 1865(7):959-969, 2018. e-Pub 2018. PMID: 29655803.
8. Schutt CA, Mirandola L, Figueroa JA, Nguyen DD, Cordero J, Bumm K, Judson BL, Chiriva-Internati M. The cancer-testis antigen, sperm protein 17, a new biomarker and immunological target in head and neck squamous cell carcinoma. Oncotarget 8(59):100280-100287, 2017. e-Pub 2017. PMID: 29245977.
9. Mirandola L, Pedretti E, Figueroa JA, Chiaramonte R, Colombo M, Chapman C, Grizzi F, Patrinicola F, Kast WM, Nguyen DD, Rahman RL, Daver N, Ruvolo P, Post SM, Bresalier RS, Chiriva-Internati M. Cancer testis antigen Sperm Protein 17 as a new target for triple negative breast cancer immunotherapy. Oncotarget 8(43):74378-74390, 2017. e-Pub 2017. PMID: 29088794.
10. Grizzi F, Franceschini B, Di Biccari S, Musardo S, Pedretti E, Chiriva-Internati M, Osipov V, Fernandez-Acenero MJ. Sperm protein 17 and AKAP-associated sperm protein cancer/testis antigens are expressed in ciliated hepatic foregut cysts. Histopathology 67(3):398-403, 2015. e-Pub 2015. PMID: 25600306.
11. Cao M, Chiriva-Internati M, Hermonat PL. AAV2 X increases AAV6 rep/cap-driven rAAV production. Virology 482:84-8, 2015. e-Pub 2015. PMID: 25838114.
12. Cao M, Theus SA, Straub KD, Figueroa JA, Mirandola L, Chiriva-Internati M, Hermonat PL. AAV2/8-humanFOXP3 gene therapy shows robust anti-atherosclerosis efficacy in LDLR-KO mice on high cholesterol diet. J Transl Med 13:235, 2015. e-Pub 2015. PMID: 26187646.
13. Mirandola L, Figueroa JA, Phan TT, Grizzi F, Kim M, Rahman RL, Jenkins MR, Cobos E, Jumper C, Alalawi R, Chiriva-Internati M. Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets. Oncotarget 6(5):2812-26, 2015. e-Pub 2015. PMID: 25739119.
14. Mirandola L, Yu Y, Cannon MJ, Jenkins MR, Rahman RL, Nguyen DD, Grizzi F, Cobos E, Figueroa JA, Chiriva-Internati M. Galectin-3 inhibition suppresses drug resistance, motility, invasion and angiogenic potential in ovarian cancer. Gynecol Oncol 135(3):573-9, 2014. e-Pub 2014. PMID: 25284038.
15. Colombo M, Thummler K, Mirandola L, Garavelli S, Todoerti K, Apicella L, Lazzari E, Lancellotti M, Platonova N, Akbar M, Chiriva-Internati M, Soutar R, Neri A, Goodyear CS, Chiaramonte R. Notch signaling drives multiple myeloma induced osteoclastogenesis. Oncotarget 5(21):10393-406, 2014. e-Pub 2014. PMID: 25257302.
16. Zhu H, Cao M, Figueroa JA, Cobos E, Uretsky BF, Chiriva-Internati M, Hermonat PL. AAV2/8-hSMAD3 gene delivery attenuates aortic atherogenesis, enhances Th2 response without fibrosis, in LDLR-KO mice on high cholesterol diet. J Transl Med 12:252, 2014. e-Pub 2014. PMID: 25236373.
17. Chiriva-Internati M, Mirandola L, Figueroa JA, Yu Y, Grizzi F, Kim M, Jenkins M, Cobos E, Jumper C, Alalawi R. Selective expression and immunogenicity of the cancer/testis antigens SP17, AKAP4 and PTTG1 in non-small cell lung cancer: new candidates for active immunotherapy. Chest, 2014. e-Pub 2014. PMID: 24811938.
18. Zhu H, Cao M, Mirandola L, Figueroa JA, Cobos E, Chiriva-Internati M, Hermonat PL. Comparison of efficacy of the disease-specific LOX1- and constitutive cytomegalovirus-promoters in expressing interleukin 10 through adeno-associated virus 2/8 delivery in atherosclerotic mice. PLoS One 9(4):e94665, 2014. e-Pub 2014. PMID: 24736312.
19. Mirandola L, Apicella L, Colombo M, Yu Y, Berta DG, Platonova N, Lazzari E, Lancellotti M, Bulfamante G, Cobos E, Chiriva-Internati M, Chiaramonte R. Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1. Leukemia 27(7):1558-66, 2013. e-Pub 2013. PMID: 23354012.
20. Cannon MJ, Goyne HE, Stone PJ, Macdonald LJ, James LE, Cobos E, Chiriva-Internati M. Modulation of p38 MAPK signaling enhances dendritic cell activation of human CD4+ Th17 responses to ovarian tumor antigen. Cancer Immunol Immunother 62(5):839-49, 2013. e-Pub 2013. PMID: 23354626.
21. Grizzi F, Di Caro G, Laghi L, Hermonat P, Mazzola P, Nguyen DD, Radhi S, Figueroa JA, Cobos E, Annoni G, Chiriva-Internati M. Mast cells and the liver aging process. Immun Ageing 10(1):9, 2013. e-Pub 2013. PMID: 23496863.
22. Bava A, Cappellini F, Pedretti E, Rossi F, Caruso E, Vismara E, Chiriva-Internati M, Bernardini G, Gornati R. Heparin and carboxymethylchitosan metal nanoparticles: an evaluation of their cytotoxicity. Biomed Res Int 2013:314091, 2013. e-Pub 2013. PMID: 23509708.
23. Tawde SA, Chablani L, Akalkotkar A, D'Souza C, Chiriva-Internati M, Selvaraj P, D'Souza MJ. Formulation and evaluation of oral microparticulate ovarian cancer vaccines. Vaccine 30(38):5675-81, 2012. e-Pub 2012. PMID: 22750042.
24. Mazzola P, Radhi S, Mirandola L, Annoni G, Jenkins M, Cobos E, Chiriva-Internati M. Aging, cancer, and cancer vaccines. Immun Ageing 9(1):4, 2012. e-Pub 2012. PMID: 22510392.
25. Mirandola L, Chiriva-Internati M, Montagna D, Locatelli F, Zecca M, Ranzani M, Basile A, Locati M, Cobos E, Kast WM, Asselta R, Paraboschi EM, Comi P, Chiaramonte R. Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia. J Pathol 226(5):713-22, 2012. e-Pub 2012. PMID: 21984373.
26. Chiriva-Internati M, Yu Y, Mirandola L, D'Cunha N, Hardwicke F, Cannon MJ, Cobos E, Kast WM. Identification of AKAP-4 as a new cancer/testis antigen for detection and immunotherapy of prostate cancer. Prostate 72(1):12-23, 2012. e-Pub 2012. PMID: 21520158.
27. Mirandola L, Yu Y, Jenkins MR, Chiaramonte R, Cobos E, John CM, Chiriva-Internati M. Tracking human multiple myeloma xenografts in NOD-Rag-1/IL-2 receptor gamma chain-null mice with the novel biomarker AKAP-4. BMC Cancer 11:394, 2011. e-Pub 2011. PMID: 21923911.
28. Chiriva-Internati M, Mirandola L, Yu Y, Jenkins MR, Gornati R, Bernardini G, Gioia M, Chiaramonte R, Cannon MJ, Kast WM, Cobos E. Cancer testis antigen, ropporin, is a potential target for multiple myeloma immunotherapy. J Immunother 34(6):490-9, 2011. e-Pub 2011. PMID: 21654522.
29. Mirandola L, Yu Y, Chui K, Jenkins MR, Cobos E, John CM, Chiriva-Internati M. Galectin-3C inhibits tumor growth and increases the anticancer activity of bortezomib in a murine model of human multiple myeloma. PLoS One 6(7):e21811, 2011. e-Pub 2011. PMID: 21765917.
30. Chiriva-Internati M, Yu Y, Mirandola L, Jenkins MR, Chapman C, Cannon M, Cobos E, Kast WM. Cancer testis antigen vaccination affords long-term protection in a murine model of ovarian cancer. PLoS One 5(5):e10471, 2010. e-Pub 2010. PMID: 20485677.
31. Funel N, Costa F, Pettinari L, Taddeo A, Sala A, Chiriva-Internati M, Cobos E, Colombo G, Milzani A, Campani D, Dalle-Donne I, Gagliano N. Ukrain affects pancreas cancer cell phenotype in vitro by targeting MMP-9 and intra-/extracellular SPARC expression. Pancreatology 10(5):545-52, 2010. e-Pub 2010. PMID: 20975318.
32. Gagliano N, Costa F, Cossetti C, Pettinari L, Bassi R, Chiriva-Internati M, Cobos E, Gioia M, Pluchino S. Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model. Oncol Rep 22(6):1349-56, 2009. e-Pub 2009. PMID: 19885586.
33. Chiriva-Internati M, Gagliano N, Donetti E, Costa F, Grizzi F, Franceschini B, Albani E, Levi-Setti PE, Gioia M, Jenkins M, Cobos E, Kast WM. Sperm protein 17 is expressed in the sperm fibrous sheath. J Transl Med 7:61, 2009. e-Pub 2009. PMID: 19604394.
34. Li Yumin, Chen Hao, Li Xun, Zhou Wence, He Minyan, Chiriva-Internati M, Wachtel MS, Frezza EE. A new immunomodulatory therapy for severe sepsis: Ulinastatin Plus Thymosin alpha 1. J Intensive Care Med 24(1):47-53, 2009. e-Pub 2009. PMID: 19033321.
35. Gagliano N, Pelillo F, Chiriva-Internati M, Picciolini O, Costa F, Schutt RC Jr, Gioia M, Portinaro N. Expression profiling of genes involved in collagen turnover in tendons from cerebral palsy patients. Connect Tissue Res 50(3):203-8, 2009. e-Pub 2009. PMID: 19444761.
36. Sanchez A, Chiriva-Internati M, Grammas P. Transduction of PACAP38 protects primary cortical neurons from neurotoxic injury. Neurosci Lett 448(1):52-5, 2008. e-Pub 2008. PMID: 18938212.
37. Yu Y, Pilgrim P, Zhou W, Gagliano N, Frezza EE, Jenkins M, Weidanz JA, Lustgarten J, Cannon M, Bumm K, Cobos E, Kast WM, Chiriva-Internati M. rAAV/Her-2/neu loading of dendritic cells for a potent cellular-mediated MHC class I restricted immune response against ovarian cancer. Viral Immunol 21(4):435-42, 2008. e-Pub 2008. PMID: 19115932.
38. Yu Y, Pilgrim P, Yan J, Zhou W, Jenkins M, Gagliano N, Bumm K, Cannon M, Milzani A, Dalle-Donne I, Kast WM, Cobos E, Chiriva-Internati M. Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells. J Transl Med 6:56, 2008. e-Pub 2008. PMID: 18834548.
39. Chiriva-Internati M, Weidanz JA, Yu Y, Frezza EE, Jenkins MR, Kennedy RC, Cobos E, Kast WM. Sperm protein 17 is a suitable target for adoptive T-cell-based immunotherapy in human ovarian cancer. J Immunother 31(8):693-703, 2008. e-Pub 2008. PMID: 18779750.
40. Gagliano N, Moscheni C, Tartaglia GM, Selleri S, Chiriva-Internati M, Cobos E, Torri C, Costa F, Pettinari L, Gioia M. A therapeutic dose of FK506 does not affect collagen turnover pathways in healthy human gingival fibroblasts. Transplant Proc 40(5):1419-24, 2008. e-Pub 2008. PMID: 18589121.
41. Chiriva-Internati M, Ferrari R, Prabhakar M, Yu Y, Baggoni L, Moreno J, Gagliano N, Portinaro N, Jenkins MR, Frezza EE, Hardwicke F, D'Cunha N, Kast W, Cobos E. The pituitary tumor transforming gene 1 (PTTG-1): an immunological target for multiple myeloma. J Transl Med 6:15, 2008. e-Pub 2008. PMID: 18384692.
42. Zhou L, Liu P, Chen B, Wang Y, Wang X, Chiriva Internati M, Wachtel MS, Frezza EE. Silibinin restores paclitaxel sensitivity to paclitaxel-resistant human ovarian carcinoma cells. Anticancer Res 28(2A):1119-27, 2008. e-Pub 2008. PMID: 18507063.
43. Wachtel MS, Xu KT, Zhang Y, Chiriva-Internati M, Frezza EE. Pancreas cancer survival in the gemcitabine era. Clin Med Oncol 2:405-13, 2008. e-Pub 2008. PMID: 21892307.
44. Wachtel MS, Zhang Y, Xu T, Chiriva-Internati M, Frezza EE. Combined hepatocellular cholangiocarcinomas; analysis of a large database. Clin Med Pathol 1:43-7, 2008. e-Pub 2008. PMID: 21876650.
45. Gagliano N, Bedoni M, Mantovani G, Chiriva-Internati M, Castelli D, Torri C, Donetti E. Effect of a topical treatment in organotypic culture of human breast skin after exposure to gamma-rays. Eur J Histochem 51(4):283-90, 2007. e-Pub 2007. PMID: 18162458.
46. Wachtel MS, Zhang Y, Kaye KE, Chiriva-Internati M, Frezza EE. Increased age, male gender, and cirrhosis, but not steatosis or a positive viral serology, negatively impact the life expectancy of patients who undergo liver biopsy. Dig Dis Sci 52(9):2276-81, 2007. e-Pub 2007. PMID: 17406827.
47. Frezza EE, Wachtel MS, Barragan B, Chiriva-Internati M, Cobos E. The role of radiofrequency ablation in multiple liver metastases to debulk the tumor: a pilot study before alternative therapies. J Laparoendosc Adv Surg Tech A 17(3):282-4, 2007. e-Pub 2007. PMID: 17570770.
48. Chiriva-Internati M, Grizzi F, Weidanz JA, Ferrari R, Yuefei Y, Velez B, Shearer MH, Lowe DB, Frezza EE, Cobos E, Kast WM, Kennedy RC. A NOD/SCID tumor model for human ovarian cancer that allows tracking of tumor progression through the biomarker Sp17. J Immunol Methods 321(1-2):86-93, 2007. e-Pub 2007. PMID: 17336323.
49. Weidanz JA, Piazza P, Hickman-Miller H, Woodburn D, Nguyen T, Wahl A, Neethling F, Chiriva-Internati M, Rinaldo CR, Hildebrand WH. Development and implementation of a direct detection, quantitation and validation system for class I MHC self-peptide epitopes. J Immunol Methods 318(1-2):47-58, 2007. e-Pub 2007. PMID: 17134715.
50. Grizzi F, Chiriva-Internati M. Human binucleate hepatocytes: are they a defence during chronic liver diseases?. Med Hypotheses 69(2):258-61, 2007. e-Pub 2007. PMID: 17307305.
51. Thomas S, Chiriva-Internati M, Shah GV. Calcitonin receptor-stimulated migration of prostate cancer cells is mediated by urokinase receptor-integrin signaling. Clin Exp Metastasis 24(5):363-77, 2007. e-Pub 2007. PMID: 17487556.
52. Weidanz JA, Nguyen T, Woodburn T, Neethling FA, Chiriva-Internati M, Hildebrand WH, Lustgarten J. Levels of specific peptide-HLA class I complex predicts tumor cell susceptibility to CTL killing. J Immunol 177(8):5088-97, 2006. e-Pub 2006. PMID: 17015692.
53. Wachtel MS, Zhang Y, Chiriva-Internati M, Frezza EE. Different regression equations relate age to the incidence of Lauren types 1 and 2 stomach cancer in the SEER database: these equations are unaffected by sex or race. BMC Cancer 6:65, 2006. e-Pub 2006. PMID: 16539725.
54. Chiriva-Internati M, Grizzi F, Pinkston J, Morrow KJ, D'Cunha N, Frezza EE, Muzzio PC, Kast WM, Cobos E. Gamma-radiation upregulates MHC class I/II and ICAM-I molecules in multiple myeloma cell lines and primary tumors. In Vitro Cell Dev Biol Anim 42(3-4):89-95, 2006. e-Pub 2006. PMID: 16759154.
55. Grizzi F, Chiriva-Internati M. Cancer: looking for simplicity and finding complexity. Cancer Cell Int 6:4, 2006. e-Pub 2006. PMID: 16480511.
56. Grizzi F, Gaetani P, Franceschini B, Di Ieva A, Colombo P, Ceva-Grimaldi G, Bollati A, Frezza EE, Cobos E, Rodriguez y Baena R, Dioguardi N, Chiriva-Internati M. Sperm protein 17 is expressed in human nervous system tumours. BMC Cancer 6:23, 2006. e-Pub 2006. PMID: 16438728.
57. Bumm K, Grizzi F, Franceschini B, Koch M, Iro H, Wurm J, Ceva-Grimaldi G, Dimmler A, Cobos E, Dioguardi N, Sinha UK, Kast WM, Chiriva-Internati M. Sperm protein 17 expression defines 2 subsets of primary esthesioneuroblastoma. Hum Pathol 36(12):1289-93, 2005. e-Pub 2005. PMID: 16311122.
58. Sabbisetti VS, Chirugupati S, Thomas S, Vaidya KS, Reardon D, Chiriva-Internati M, Iczkowski KA, Shah GV. Calcitonin increases invasiveness of prostate cancer cells: role for cyclic AMP-dependent protein kinase A in calcitonin action. Int J Cancer 117(4):551-60, 2005. e-Pub 2005. PMID: 15929083.
59. Grizzi F, Chiriva-Internati M. The complexity of anatomical systems. Theor Biol Med Model 2:26, 2005. e-Pub 2005. PMID: 16029490.
60. Weidanz JA, Jacobson LM, Muehrer RJ, Djamali A, Hullett DA, Sprague J, Chiriva-Internati M, Wittman V, Thekkumkara TJ, Becker BN. ATR blockade reduces IFN-gamma production in lymphocytes in vivo and in vitro. Kidney Int 67(6):2134-42, 2005. e-Pub 2005. PMID: 15882256.
61. Liu Y, Chiriva-Internati M, You C, Luo R, You H, Prasad CK, Grizzi F, Cobos E, Klimberg VS, Kay H, Mehta JL, Hermonat PL. Use and specificity of breast cancer antigen/milk protein BA46 for generating anti-self-cytotoxic T lymphocytes by recombinant adeno-associated virus-based gene loading of dendritic cells. Cancer Gene Ther 12(3):304-12, 2005. e-Pub 2005. PMID: 15565181.
62. Grizzi F, Russo C, Colombo P, Franceschini B, Frezza EE, Cobos E, Chiriva-Internati M. Quantitative evaluation and modeling of two-dimensional neovascular network complexity: the surface fractal dimension. BMC Cancer 5:14, 2005. e-Pub 2005. PMID: 15701176.
63. Kennedy RC, Shearer MH, Lowe DB, Jumper CA, Chiriva-Internati M, Bright RK. Anti-idiotype responses abrogate anti-CD4-induced tolerance to a tumor-specific antigen and promote systemic tumor immunity. Cancer Immunol Immunother 53(11):987-94, 2004. e-Pub 2004. PMID: 15156293.
64. Agrawal N, You H, Liu Y, Chiriva-Internati M, Bremner J, Garg T, Grizzi F, Krishna Prasad C, Mehta JL, Hermonat PL. Generation of recombinant skin in vitro by adeno-associated virus type 2 vector transduction. Tissue Eng 10(11-12):1707-15, 2004. e-Pub 2004. PMID: 15684679.
65. Grizzi F, Chiriva-Internati M, Franceschini B, Bumm K, Colombo P, Ciccarelli M, Donetti E, Gagliano N, Hermonat PL, Bright RK, Gioia M, Dioguardi N, Kast WM. Sperm protein 17 is expressed in human somatic ciliated epithelia. J Histochem Cytochem 52(4):549-54, 2004. e-Pub 2004. PMID: 15034007.
66. Straughn JM Jr, Shaw DR, Guerrero A, Bhoola SM, Racelis A, Wang Z, Chiriva-Internati M, Grizzle WE, Alvarez RD, Lim SH, Strong TV. Expression of sperm protein 17 (Sp17) in ovarian cancer. Int J Cancer 108(6):805-11, 2004. e-Pub 2004. PMID: 14712480.
67. Grizzi F, Russo C, Portinaro N, Hermonat PL, Chiriva-Internati M. Complexity and cancer. Gastroenterology 126(2):630-1; author reply 631-2, 2004. e-Pub 2004. PMID: 14765401.
68. Chiriva-Internati M, Wang Z, Pochopien S, Salati E, Lim SH. Identification of a sperm protein 17 CTL epitope restricted by HLA-A1. Int J Cancer 107(5):863-5, 2003. e-Pub 2003. PMID: 14566839.
69. You H, Liu Y, Agrawal N, Prasad CK, Chiriva-Internati M, Lowery CL, Kay HH, Hermonat PL. Infection, replication, and cytopathology of human papillomavirus type 31 in trophoblasts. Virology 316(2):281-9, 2003. e-Pub 2003. PMID: 14644610.
70. Chiriva-Internati M, Liu Y, Weidanz JA, Grizzi F, You H, Zhou W, Bumm K, Barlogie B, Mehta JL, Hermonat PL. Testing recombinant adeno-associated virus-gene loading of dendritic cells for generating potent cytotoxic T lymphocytes against a prototype self-antigen, multiple myeloma HM1.24. Blood 102(9):3100-7, 2003. e-Pub 2003. PMID: 12855576.
71. Prasad CK, Meyers C, Zhan DJ, You H, Chiriva-Internati M, Mehta JL, Liu Y, Hermonat PL. The adeno-associated virus major regulatory protein Rep78-c-Jun-DNA motif complex modulates AP-1 activity. Virology 314(1):423-31, 2003. e-Pub 2003. PMID: 14517094.
72. Grizzi F, Chiriva-Internati M, Franceschini B, Hermonat PL, Soda G, Lim SH, Dioguardi N. Immunolocalization of sperm protein 17 in human testis and ejaculated spermatozoa. J Histochem Cytochem 51(9):1245-8, 2003. e-Pub 2003. PMID: 12923251.
73. Grizzi F, Franceschini B, Chiriva-Internati M, Liu Y, Hermonat PL, Dioguardi N. Mast cells and human hepatocellular carcinoma. World J Gastroenterol 9(7):1469-73, 2003. e-Pub 2003. PMID: 12854143.
74. Grizzi F, Franceschini B, Gagliano N, Moscheni C, Annoni G, Vergani C, Hermonat PL, Chiriva-Internati M, Dioguardi N. Mast cell density, hepatic stellate cell activation and TGF-beta1 transcripts in the aging Sprague-Dawley rat during early acute liver injury. Toxicol Pathol 31(2):173-8, 2003. e-Pub 2003. PMID: 12696576.
75. Wang Z, Zhang Y, Liu H, Salati E, Chiriva-Internati M, Lim SH. Gene expression and immunologic consequence of SPAN-Xb in myeloma and other hematologic malignancies. Blood 101(3):955-60, 2003. e-Pub 2003. PMID: 12393489.
76. Chiriva-Internati M, Wang Z, Salati E, Wroblewski D, Lim SH. Successful generation of sperm protein 17 (Sp17)-specific cytotoxic T lymphocytes from normal donors: implication for tumour-specific adoptive immunotherapy following allogeneic stem cell transplantation for Sp17-positive multiple myeloma. Scand J Immunol 56(4):429-33, 2002. e-Pub 2002. PMID: 12234264.
77. Chiriva-Internati M, Wang Z, Salati E, Bumm K, Barlogie B, Lim SH. Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma. Blood 100(3):961-5, 2002. e-Pub 2002. PMID: 12130509.
78. Agrawal N, Mane M, Chiriva-Internati M, Roman JJ, Hermonat PL. Temporal acceleration of the human papillomavirus life cycle by adeno-associated virus (AAV) type 2 superinfection in natural host tissue. Virology 297(2):203-10, 2002. e-Pub 2002. PMID: 12083819.
79. Chiriva-Internati M, Wang Z, Salati E, Timmins P, Lim SH. Tumor vaccine for ovarian carcinoma targeting sperm protein 17. Cancer 94(9):2447-53, 2002. e-Pub 2002. PMID: 12015770.
80. Grizzi F, Franceschini B, Barbieri B, Gagliano N, Arosio B, Chiriva-Internati M, Annoni G, Dioguardi N. Mast cell density: a quantitative index of acute liver inflammation. Anal Quant Cytol Histol 24(2):63-9, 2002. e-Pub 2002. PMID: 12026051.
81. Bumm K, Zheng M, Bailey C, Zhan F, Chiriva-Internati M, Eddlemon P, Terry J, Barlogie B, Shaughnessy JD Jr. CGO: utilizing and integrating gene expression microarray data in clinical research and data management. Bioinformatics 18(2):327-8, 2002. e-Pub 2002. PMID: 11847084.
82. Chiriva-Internati M, Liu Y, Salati E, Zhou W, Wang Z, Grizzi F, Roman JJ, Lim SH, Hermonat PL. Efficient generation of cytotoxic T lymphocytes against cervical cancer cells by adeno-associated virus/human papillomavirus type 16 E7 antigen gene transduction into dendritic cells. Eur J Immunol 32(1):30-8, 2002. e-Pub 2002. PMID: 11754001.
83. Grizzi F, Ceva-Grimaldi G, Franceschini B, Roncalli M, Chiriva-Internati M, Dioguardi N. Simultaneous staining of cytoplasmic iron and collagen matrix in human liver biopsy specimens. Eur J Histochem 46(1):101-4, 2002. e-Pub 2002. PMID: 12044042.
84. Liu Y, Chiriva-Internati M, Grizzi F, Salati E, Roman JJ, Lim S, Hermonat PL. Rapid induction of cytotoxic T-cell response against cervical cancer cells by human papillomavirus type 16 E6 antigen gene delivery into human dendritic cells by an adeno-associated virus vector. Cancer Gene Ther 8(12):948-57, 2001. e-Pub 2001. PMID: 11781657.
85. Liu Y, You H, Chiriva-Internati M, Korourian S, Lowery CL, Carey MJ, Smith CV, Hermonat PL. Display of complete life cycle of human papillomavirus type 16 in cultured placental trophoblasts. Virology 290(1):99-105, 2001. e-Pub 2001. PMID: 11887784.
86. Liu Y, Klimberg VS, Andrews NR, Hicks CR, Peng H, Chiriva-Internati M, Henry-Tillman R, Hermonat PL. Human papillomavirus DNA is present in a subset of unselected breast cancers. J Hum Virol 4(6):329-34, 2001. e-Pub 2001. PMID: 12082399.
87. Lim SH, Bumm K, Chiriva-Internati M, Xue Y, Wang Z. MAGE-C1 (CT7) gene expression in multiple myeloma: relationship to sperm protein 17. Eur J Haematol 67(5-6):332-4, 2001. e-Pub 2001. PMID: 11872084.
88. Chiriva-Internati M, Wang Z, Xue Y, Bumm K, Hahn AB, Lim SH. Sperm protein 17 (Sp17) in multiple myeloma: opportunity for myeloma-specific donor T cell infusion to enhance graft-versus-myeloma effect without increasing graft-versus-host disease risk. Eur J Immunol 31(8):2277-83, 2001. e-Pub 2001. PMID: 11477539.
89. Lim SH, Wang Z, Chiriva-Internati M, Xue Y. Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma. Blood 97(5):1508-10, 2001. e-Pub 2001. PMID: 11222401.
90. Chiriva-Internati M, Du J, Cannon M, Barlogie B, Yi Q. Myeloma-reactive allospecific cytotoxic T lymphocytes lyse target cells via the granule exocytosis pathway. Br J Haematol 112(2):410-20, 2001. e-Pub 2001. PMID: 11167840.
91. Liu Y, Santin AD, Mane M, Chiriva-Internati M, Parham GP, Ravaggi A, Hermonat PL. Transduction and utility of the granulocyte-macrophage colony-stimulating factor gene into monocytes and dendritic cells by adeno-associated virus. J Interferon Cytokine Res 20(1):21-30, 2000. e-Pub 2000. PMID: 10670649.
92. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Zhan D, Pecorelli S, Parham GP, Cannon MJ. Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer. J Virol 73(7):5402-10, 1999. e-Pub 1999. PMID: 10364287.
93. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Cannon MJ, Hiserodt JC, Pecorelli S, Parham GP. Expression of surface antigens during the differentiation of human dendritic cells vs macrophages from blood monocytes in vitro. Immunobiology 200(2):187-204, 1999. e-Pub 1999. PMID: 10416127.
94. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Pecorelli S, Parham GP. Radiation-enhanced expression of E6/E7 transforming oncogenes of human papillomavirus-16 in human cervical carcinoma. Cancer 83(11):2346-52, 1998. e-Pub 1998. PMID: 9840534.
95. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Pecorelli S, Parham GP. Retinoic acid up-regulates the expression of major histocompatibility complex molecules and adhesion/costimulation molecules (specifically, intercellular adhesion molecule ICAM-1) in human cervical cancer. Am J Obstet Gynecol 179(4):1020-5, 1998. e-Pub 1998. PMID: 9790391.
96. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Hiserodt JC, Pecorelli S, Parham GP. Effects of retinoic acid combined with irradiation on the expression of major histocompatibility complex molecules and adhesion/costimulation molecules ICAM-1 in human cervical cancer. Gynecol Oncol 70(2):195-201, 1998. e-Pub 1998. PMID: 9740690.
97. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Hiserodt JC, Batchu RB, Pecorelli S, Parham GP. The effects of irradiation on the expression of a tumour rejection antigen (heat shock protein gp96) in human cervical cancer. Int J Radiat Biol 73(6):699-704, 1998. e-Pub 1998. PMID: 9690688.
98. Santin AD, Hermonat P, Ravaggi A, Chiriva-Internati M, Hiserodt JC, Tian E, Carter CA, Pecorelli S, Parham GP. Effects of retinoic acid combined with interferon-gamma on the expression of major-histocompatibility-complex molecules and intercellular adhesion molecule-1 in human cervical cancer. Int J Cancer 75(2):254-8, 1998. e-Pub 1998. PMID: 9462716.
99. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Pecorelli S, Parham GP. Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer. Eur J Gynaecol Oncol 19(3):229-33, 1998. e-Pub 1998. PMID: 9641219.
100. Santin AD, Hermonat PL, Hiserodt JC, Chiriva-Internati M, Woodliff J, Theus JW, Barclay D, Pecorelli S, Parham GP. Effects of irradiation on the expression of major histocompatibility complex class I antigen and adhesion costimulation molecules ICAM-1 in human cervical cancer. Int J Radiat Oncol Biol Phys 39(3):737-42, 1997. e-Pub 1997. PMID: 9336157.

Review Articles

1. Grizzi F, Bax C, Farina FM, Tidu L, Hegazi MAAA, Chiriva-Internati M, Capelli L, Robbiani S, Dellaca R, Taverna G. Recapitulating COVID-19 detection methods: RT-PCR, sniffer dogs and electronic nose. Diagn Microbiol Infect Dis 110(1):116430, 2024. e-Pub 2024. PMID: 38996774.
2. Grizzi F, Hegazi MAAA, Zanoni M, Vota P, Toia G, Clementi MC, Mazzieri C, Chiriva-Internati M, Taverna G. Prostate Cancer Microvascular Routes: Exploration and Measurement Strategies. Life (Basel) 13(10), 2023. e-Pub 2023. PMID: 37895416.
3. Grizzi F, Spadaccini M, Chiriva-Internati M, Hegazi MAAA, Bresalier RS, Hassan C, Repici A, Carrara S. Fractal nature of human gastrointestinal system: Exploring a new era. World J Gastroenterol 29(25):4036-4052, 2023. e-Pub 2023. PMID: 37476585.
4. Taverna G, Di Francesco S, Borroni EM, Yiu D, Toniato E, Milanesi S, Chiriva-Internati M, Bresalier RS, Zanoni M, Vota P, Maffei D, Justich M, Grizzi F. The kidney, COVID-19, and the chemokine network: an intriguing trio. Int Urol Nephrol 53(1):97-104, 2021. e-Pub 2021. PMID: 32720031.
5. Grizzi F, Basso G, Borroni EM, Cavalleri T, Bianchi P, Stifter S, Chiriva-Internati M, Malesci A, Laghi L. Evolving notions on immune response in colorectal cancer and their implications for biomarker development. Inflamm Res 67(5):375-389, 2018. e-Pub 2018. PMID: 29322204.
6. Colombo M, Mirandola L, Chiriva-Internati M, Basile A, Locati M, Lesma E, Chiaramonte R, Platonova N. Cancer Cells Exploit Notch Signaling to Redefine a Supportive Cytokine Milieu. Front Immunol 9:1823, 2018. e-Pub 2018. PMID: 30154786.
7. Parzanese I, Qehajaj D, Patrinicola F, Aralica M, Chiriva-Internati M, Stifter S, Elli L, Grizzi F. Celiac disease: From pathophysiology to treatment. World J Gastrointest Pathophysiol 8(2):27-38, 2017. e-Pub 2017. PMID: 28573065.
8. Colombo M, Mirandola L, Reidy A, Suvorava N, Konala V, Chiaramonte R, Grizzi F, Rahman RL, Jenkins MR, Nugyen DD, Dalhbeck S, Cobos E, Figueroa JA, Chiriva-Internati M. Targeting Tumor Initiating Cells through Inhibition of Cancer Testis Antigens and Notch Signaling: A Hypothesis. Int Rev Immunol 34(2):188-99, 2015. e-Pub 2015. PMID: 25901861.
9. Figueroa JA, Reidy A, Mirandola L, Trotter K, Suvorava N, Figueroa A, Konala V, Aulakh A, Littlefield L, Grizzi F, Rahman RL, Jenkins MR, Musgrove B, Radhi S, D'Cunha N, D'Cunha LN, Hermonat PL, Cobos E, Chiriva-Internati M. Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy. Int Rev Immunol 34(2):154-87, 2015. e-Pub 2015. PMID: 25901860.
10. Grizzi F, Mirandola L, Qehajaj D, Cobos E, Figueroa JA, Chiriva-Internati M. Cancer-testis antigens and immunotherapy in the light of cancer complexity. Int Rev Immunol 34(2):143-53, 2015. e-Pub 2015. PMID: 25901859.
11. Mirandola L, Wade R, Verma R, Pena C, Hosiriluck N, Figueroa JA, Cobos E, Jenkins MR, Chiriva-Internati M. Sex-driven differences in immunological responses: challenges and opportunities for the immunotherapies of the third millennium. Int Rev Immunol 34(2):134-42, 2015. e-Pub 2015. PMID: 25901858.
12. Di Caro G, Castino GF, Bergomas F, Cortese N, Chiriva-Internati M, Grizzi F, Mantovani A, Marchesi F. Tertiary lymphoid tissue in the tumor microenvironment: from its occurrence to immunotherapeutic implications. Int Rev Immunol 34(2):123-33, 2015. e-Pub 2015. PMID: 25901857.
13. Lu C, Figueroa JA, Liu Z, Konala V, Aulakh A, Verma R, Cobos E, Chiriva-Internati M, Gao W. Nuclear Export as a Novel Therapeutic Target: The CRM1 Connection. Curr Cancer Drug Targets 15(7):575-92, 2015. e-Pub 2015. PMID: 26324128.
14. Grizzi F, Borroni EM, Vacchini A, Qehajaj D, Liguori M, Stifter S, Chiriva-Internati M, Di Ieva A. Pituitary Adenoma and the Chemokine Network: A Systemic View. Front Endocrinol (Lausanne) 6:141, 2015. e-Pub 2015. PMID: 26441831.
15. Cobos C, Figueroa JA, Mirandola L, Colombo M, Summers G, Figueroa A, Aulakh A, Konala V, Verma R, Riaz J, Wade R, Saadeh C, Rahman RL, Pandey A, Radhi S, Nguyen DD, Jenkins M, Chiriva-Internati M, Cobos E. The role of human papilloma virus (HPV) infection in non-anogenital cancer and the promise of immunotherapy: a review. Int Rev Immunol 33(5):383-401, 2014. e-Pub 2014. PMID: 24811210.
16. Mirandola L, Nguyen DD, Rahman RL, Grizzi F, Yuefei Y, Figueroa JA, Jenkins MR, Cobos E, Chiriva-Internati M. Anti-galectin-3 therapy: a new chance for multiple myeloma and ovarian cancer?. Int Rev Immunol 33(5):417-27, 2014. e-Pub 2014. PMID: 24801755.
17. Arnaboldi F, Menon A, Menegola E, Di Renzo F, Mirandola L, Grizzi F, Figueroa JA, Cobos E, Jenkins M, Barajon I, Chiriva-Internati M. Sperm protein 17 is an oncofetal antigen: a lesson from a murine model. Int Rev Immunol 33(5):367-74, 2014. e-Pub 2014. PMID: 24811209.
18. Di Caro G, Castino GF, Bergomas F, Cortese N, Chiriva-Internati M, Grizzi F, Marchesi F. Immune-based therapies in pancreatic and colorectal cancers and biomarkers of responsiveness. Expert Rev Anticancer Ther 14(10):1219-28, 2014. e-Pub 2014. PMID: 25222571.
19. Ebrahim AH, Alalawi Z, Mirandola L, Rakhshanda R, Dahlbeck S, Nguyen D, Jenkins M, Grizzi F, Cobos E, Figueroa JA, Chiriva-Internati M. Galectins in cancer: carcinogenesis, diagnosis and therapy. Ann Transl Med 2(9):88, 2014. e-Pub 2014. PMID: 25405163.
20. Pena C, Mirandola L, Figueroa JA, Hosiriluck N, Suvorava N, Trotter K, Reidy A, Rakhshanda R, Payne D, Jenkins M, Grizzi F, Littlefield L, Chiriva-Internati M, Cobos E. Galectins as therapeutic targets for hematological malignancies: a hopeful sweetness. Ann Transl Med 2(9):87, 2014. e-Pub 2014. PMID: 25405162.
21. Taverna G, Seveso M, Giusti G, Hurle R, Graziotti P, Stifter S, Chiriva-Internati M, Grizzi F. Senescent remodeling of the innate and adaptive immune system in the elderly men with prostate cancer. Curr Gerontol Geriatr Res 2014:478126, 2014. e-Pub 2014. PMID: 24772169.
22. Colombo M, Mirandola L, Platonova N, Apicella L, Basile A, Figueroa AJ, Cobos E, Chiriva-Internati M, Chiaramonte R. Notch-directed microenvironment reprogramming in myeloma: a single path to multiple outcomes. Leukemia 27(5):1009-18, 2013. e-Pub 2013. PMID: 23307030.
23. Chiriva-Internati M, Pandey A, Saba R, Kim M, Saadeh C, Lukman T, Chiaramonte R, Jenkins M, Cobos E, Jumper C, Alalawi R. Cancer testis antigens: a novel target in lung cancer. Int Rev Immunol 31(5):321-43, 2012. e-Pub 2012. PMID: 23083344.
24. Pandey A, Kurup A, Shrivastava A, Radhi S, Nguyen DD, Arentz C, D'Chuna N, Hardwick F, D'Souza MJ, Jenkins M, Grizzi F, Kast WM, Cobos E, Rahman R, Chiriva-Internati M, Chiaramonte R, Platonova N. Cancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability. Int Rev Immunol 31(5):302-20, 2012. e-Pub 2012. PMID: 23083343.
25. Kim M, Mirandola L, Pandey A, Nguyen DD, Jenkins MR, Turcel M, Cobos E, Chiriva-Internati M. Application of vitamin D and derivatives in hematological malignancies. Cancer Lett 319(1):8-22, 2012. e-Pub 2012. PMID: 22193723.
26. Schutt C, Bumm K, Mirandola L, Bernardini G, Cunha N, Tijani L, Nguyen D, Cordero J, Jenkins MR, Cobos E, Kast WM, Chiriva-Internati M. Immunological treatment options for locoregionally advanced head and neck squamous cell carcinoma. Int Rev Immunol 31(1):22-42, 2012. e-Pub 2012. PMID: 22251006.
27. Jenkins M, Chiriva-Internati M, Mirandola L, Tonroy C, Tedjarati SS, Davis N, D'Cunha N, Tijani L, Hardwick F, Nguyen D, Kast WM, Cobos E. Perspective for prophylaxis and treatment of cervical cancer: an immunological approach. Int Rev Immunol 31(1):3-21, 2012. e-Pub 2012. PMID: 22251005.
28. Mirandola L, Comi P, Cobos E, Kast WM, Chiriva-Internati M, Chiaramonte R. Notch-ing from T-cell to B-cell lymphoid malignancies. Cancer Lett 308(1):1-13, 2011. e-Pub 2011. PMID: 21652011.
29. Chiriva-Internati M, Mirandola L, Kast WM, Jenkins MR, Cobos E, Cannon MJ. Understanding the cross-talk between ovarian tumors and immune cells: mechanisms for effective immunotherapies. Int Rev Immunol 30(2-3):71-86, 2011. e-Pub 2011. PMID: 21557635.
30. Chiriva-Internati M. Sperm protein 17: clinical relevance of a cancer/testis antigen, from contraception to cancer immunotherapy, and beyond. Int Rev Immunol 30(2-3):138-49, 2011. e-Pub 2011. PMID: 21557640.
31. Mirandola L, J Cannon M, Cobos E, Bernardini G, Jenkins MR, Kast WM, Chiriva-Internati M. Cancer testis antigens: novel biomarkers and targetable proteins for ovarian cancer. Int Rev Immunol 30(2-3):127-37, 2011. e-Pub 2011. PMID: 21557639.
32. Cattaneo AG, Gornati R, Sabbioni E, Chiriva-Internati M, Cobos E, Jenkins MR, Bernardini G. Nanotechnology and human health: risks and benefits. J Appl Toxicol 30(8):730-44, 2010. e-Pub 2010. PMID: 21117037.
33. Chiriva-Internati M, Cobos E, Da Silva DM, Kast WM. Sperm fibrous sheath proteins: a potential new class of target antigens for use in human therapeutic cancer vaccines. Cancer Immun 8:8, 2008. e-Pub 2008. PMID: 18433090.
34. Gray A, Raff AB, Chiriva-Internati M, Chen SY, Kast WM. A paradigm shift in therapeutic vaccination of cancer patients: the need to apply therapeutic vaccination strategies in the preventive setting. Immunol Rev 222:316-27, 2008. e-Pub 2008. PMID: 18364011.
35. Chiriva-Internati M, Grizzi F, Wachtel MS, Jenkins M, Ferrari R, Cobos E, Frezza EE. Biological treatment for liver tumor and new potential biomarkers. Dig Dis Sci 53(3):836-43, 2008. e-Pub 2008. PMID: 17712633.
36. Frezza EE, Chiriva-Internati M, Wachtel MS. Analysis of the results of sleeve gastrectomy for morbid obesity and the role of ghrelin. Surg Today 38(6):481-3, 2008. e-Pub 2008. PMID: 18516524.
37. Grizzi F, Colombo P, Taverna G, Chiriva-Internati M, Cobos E, Graziotti P, Muzzio PC, Dioguardi N. Geometry of human vascular system: is it an obstacle for quantifying antiangiogenic therapies?. Appl Immunohistochem Mol Morphol 15(2):134-9, 2007. e-Pub 2007. PMID: 17525623.
38. Chiriva-Internati M, Cobos E, Kast WM. Advances in immunotherapy of multiple myeloma: from the discovery of tumor-associated antigens to clinical trials. Int Rev Immunol 26(3-4):197-222, 2007. e-Pub 2007. PMID: 17558744.
39. Frezza EE, Wachtel MS, Chiriva-Internati M. The multiple faces of glucagon-like peptide-1--obesity, appetite, and stress: what is next? A review. Dig Dis Sci 52(3):643-9, 2007. e-Pub 2007. PMID: 17268838.
40. Grizzi F, Franceschini B, Hamrick C, Frezza EE, Cobos E, Chiriva-Internati M. Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinoma. J Transl Med 5:3, 2007. e-Pub 2007. PMID: 17244360.
41. Frezza EE, Wachtel MS, Chiriva-Internati M. Influence of obesity on the risk of developing colon cancer. Gut 55(2):285-91, 2006. e-Pub 2006. PMID: 16239255.
42. Chiriva-Internati M, Grizzi F, Jumper CA, Cobos E, Hermonat PL, Frezza EE. Immunological treatment of liver tumors. World J Gastroenterol 11(42):6571-6, 2005. e-Pub 2005. PMID: 16425346.
43. Frezza EE, Chiriva-Internati M. Venous thromboembolism in morbid obesity and trauma. A review of literature. Minerva Chir 60(5):391-9, 2005. e-Pub 2005. PMID: 16210988.

Editorials

1. Chiriva-Internati M, Bot A. A new era in cancer immunotherapy: discovering novel targets and reprogramming the immune system. Int Rev Immunol 34(2):101-3, 2015. PMID: 25901856.
2. Bot A, Chiriva-Internati M. Topics in this issue: cancer testes antigens, immune checkpoints, inflammation associated with ischemia-reperfusion and integrin targeting. Int Rev Immunol 31(5):299-301, 2012. PMID: 23083342.
3. Chiriva-Internati M, Kast WM, Bot A. In this issue: targeting Human Papilloma Virus-associated disease, from cervical to head and neck carcinoma...and more. Int Rev Immunol 31(1):1-2, 2012. PMID: 22251004.
4. Chiriva-Internati M, Cobos E, Cannon MJ. Prospects and challenges for immunotherapy of ovarian cancer--what can we learn from the tumor microenvironment?. Int Rev Immunol 30(2-3):67-70, 2011. PMID: 21557634.
5. Cannon MJ, Goyne H, Stone PJ, Chiriva-Internati M. Dendritic cell vaccination against ovarian cancer--tipping the Treg/TH17 balance to therapeutic advantage?. Expert Opin Biol Ther 11(4):441-5, 2011. PMID: 21271951.
6. Grizzi F, Di Ieva A, Russo C, Frezza EE, Cobos E, Muzzio PC, Chiriva-Internati M. Cancer initiation and progression: an unsimplifiable complexity. Theor Biol Med Model 3:37, 2006. PMID: 17044918.
7. Chiriva-Internati M, Grizzi F, Bright RK, Kast WM. Cancer immunotherapy: avoiding the road to perdition. J Transl Med 2(1):26, 2004. PMID: 15283862.

Abstracts

1. Chiriva Internati M, Figueroa JA, Nguyen DD, Dahlbeck S, Chiriva-Internati M. Phase I/II study of low-dose cyclophosphamide, tumor-associated peptide antigen-pulsed dendritic cell and low dose GM-CSF for solid and hematological malignancies. Journal of Clinical Oncology 36(5_suppl), 2018. e-Pub 2018.
2. Yiu D, Grizz F, Patrinicola F, Chiriva-Internati M, Motta S, Monti M. Cutaneous melanoma microenvironment: A two-dimensional topographical computer-aided analysis as a perspective for new therapeutic strategies. Journal of Translational Medicine:15, 13, 2017. e-Pub 2017.
3. Gagliano N, Moscheni C, Annoni G, Grizzi F, Tartaglia GM, Chiriva-Internati M, Cobos E, Costa F, Gioia M. Characterization of collagen turnover pathways in human aging gingival fibroblasts. Southern Regional Meetings and the Southern Society for Clinical Investigation (SSCI) annual meeting.
4. Santin AD, Hermonat PL, Hiserodt JC, Chiriva-Internati M, Woodliff J, Barclay D, Pecorelli S, Parham GP. Expression and cytokine mediated modulation of adhesion co-stimulation molecules ICAM-1 and LFA-3 in human cervical cancer. The Soc of Gyn Oncol (SGO).
5. Santin AD, Chiriva-Internati M, Hermonat PL, Hiserodt JC, Fruehauf J, Schranz V, Barclay D, Pecorelli S, Parham GP. Differential transforming growth factor-beta (TGF-Beta) secretion in adenocarcinoma and squamous cells carcinoma of the uterine cervix. Proceedings of the American Association of Cancer Research.
6. Santin AD, Hermonat PL, Hiserodt JC, Chiriva-Internati M, Woodliff J, Barclay D, Pecorelli S, Parham GP. Effects of irradiation on the expression of major histocompatibility complex class I antigen and adhesion/co-stimulation molecules ICAM-1 in human cervical cancer. International Gynecological Cancer Society.
7. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Hiserodt JC, Pecorelli S, Parham GP. Effects of retinoic acid combined with irradiation on the expression of MHC and ICAM-1 in human cervical cancer. The Soc of Gyn Oncol (SGO).
8. Dioguardi N, Grizzi F, Chiriva-Internati M. Fractal Geometry: a useful tool in quantifying irregular liver lesion specimens by needle biopsy. Eighth Annual International Conference of the Society for Chaos Theory in Psychology and Life Sciences.
9. Grizzi F, Chiriva-Internati M, Dioguardi N. Dendritic cells: an example of structure/function correlation.
10. Hermonat PL, Ravaggi A, Chiriva-Internati M, Santin AD, Yong L. Adeno-associated virus transduction of the GM-CSF gene can replace exogenous addition of GM-CSF in the generation of cells of dendritic morphology. Cancer Gene Ther,.
11. Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Zhan DJ, Pecorelli S, Parham GP, Cannon MJ. Induction of human papillomavirus-specific CD4+ and CD8+T cell responses by E7-pulsed autologous dendritic cells in patients with HPV16 and HPV 18-positive cervical cancer. 90th Annual Meeting of the American Association for Cancer Research,.
12. Grizzi F, Chiriva-Internati M, N: D. Functional/morphological quantitative evaluation of human myeloma dendritic cells. Fifth Annual Microscopy Colloquium of the California Society for Microscopy.
13. Grizzi F, Chiriva-Internati M, Ceva-Grimaldi G, Roncalli M, Dioguardi N. Cellular accumulation of iron in hepatic fibrogenesis and histochemical condition of pathologic metabolism. 9th Convention “Actuality and the Prospective in Hepatology.
14. Straughn M, Chiriva-Internati M, Guerrero A, Wang Z, Racelis A, Terri B, Alvarez R, Strong T, Lim S. Sp17 as an Ovarian Tumor antigen. 31st Annual Meeting of the Society of Gynecologic Oncologists (SGO).
15. Grizzi F, Chiriva-Internati M, Ceva-Grimaldi G, Dioguardi N. Quantification of the liver’s morphological changes by fractal analysis. 1st Intercontinental Congress of Pathology and VIII Annual Meeting of the Portuguese Society of Cytology and XV National Congress of the Spanish Society of Cytology.
16. Grizzi F, Chiriva-Internati M, Ceva Grimaldi G, Dioguardi N. Hepatic stellate cells activation and excess iron into hepatocytes during chronic viral disease. 1st Intercontinental Congress of Pathology and VIII Annual Meeting of the Portuguese Society of Cytology and XV National Congress of the Spanish Society of Cytology.
17. Grizzi F, Chiriva-Internati M, Ceva-Grimaldi G, Dioguardi N. Complexity, Chaos Theory and Liver Carcinogenesis: A Theoretical Model. International Conference on Complex Systems (ICCS). International Conference on Complex Systems (ICCS). New England Complex Systems Institute.
18. Chiriva-Internati M, Grizzi F, Ceva-Gremaldi G, Dioguardi N. Expression of MHC antigens and adhesion/costimulation molecules of dendritic cells from human blood during their differentiation. World Congress on In Vitro Biology.
19. Chiriva-Internati M, Foddis L, Diana GM, Banni S, Gagliano N, Orbetegli O, Grizzi F. Expression of MHC antigens and adhesion/costimulation molecules of dendritic cells from human blood during their differentiation in vitro. International Congress on Immunopharmacology and Immunotherapy Today.
20. Chiriva-Internati M, Lim S, Carter C, Hermonat P, Orbetegli O, Grizzi F. 13-Cis-RA, up regulated the expression of CD40 on Dendritic Cells. International Congress on Immunopharmacology and Immunotherapy Today.
21. Wang Z, Chiriva-Internati M, Xue Y, Shaw D, Lim S. A panel of human protein 17 (SP17) murine monoclonal antibodies that may be suitable for antibody targeting of multiple myeloma. The 42nd ASH Annual Meeting.
22. Lim S, Wang Z, Chiriva-Internati M, Xue Y. Sperm Protein 17 (Sp17) is a novel cancer-testis (CT) antigen in multiple myeloma. The 42nd ASH Annual Meeting.
23. Chiriva-Internati M, Wang Z, Xue Y, Lim S. Sperm protein 17 (Sp17) primed cytotoxic T lymphocytes lyse SP-17-positive myeloma cells: potential for SP17 vaccines in Multiple Myeloma. The 42nd ASH Annual Meeting.
24. Chiriva-Internati M, Liu Y, Barlogie B, Salati E, Zhou W, Wang Z, Grizzi F, Tricot G, Hermonat P. Pulsing dendritic cells via an adeno-associated virus/HM1.24 recombinant generates rapid, significant cytotoxic T lymphocyte and interferon gamma activity against multiple myeloma and synthetic HM1.24-positive autologous targets. 10th International Conference on Gene Therapy of Cancer.
25. Hermonat P, Chiriva-Internati M, Liu Y, Barlogie B, Salati E, Zhou W, Wang Z, Grizzi F, Tricot G. Efficient generation of cytotoxic T lymphocytes against cervical cancer cells by adeno-associated virus/human papillomavirus type16 E7 antigen gene transduction into dendritic cells. 10th International Conference on Gene Therapy of Cancer.
26. Hermonat P, Chiriva-Internati M, Liu Y, Barlogie B, Salati E, Zhou W, Wang Z, Grizzi F, Tricot G. Transduction of dendritic cells by adeno-associated virus (AAV) BA46 and AVV/HER2 vector generate rapid cytotoxic T lymphocyte response against a breast cancer cell line and autologous, synthetic BA46 and HER2 positive targets. 10th International Conference on Gene Therapy of Cancer.
27. Hermonat PL, Liu Y, Chiriva-Internati M, Mane M, Grizzi F, Prasad K, Agrawal N. Secretion of GM-CSF from primary human keratinocytes and synthetic skin transduced by an adeno-associated virus vector. XI International Conference on Parvovirus.
28. Weidanz J, Wittman V, Thekkumkara T, Chiriva-Internati M. Angiotensin II regulates IFN-gamma production in human CTL line. 20th Texas Regional Immunology Conference.
29. Weidanz J, Wittman V, Thekkumkara T, Chiriva-Internati M. Angiotensin II as a modulator of T cell proliferation. 20th Texas Regional Immunology Conference.
30. Wang Z, Zhang Y, Liu H, Chiriva-Internati M, Lim S. Normal testicular antigen aberrantly expressed and induces immune response in hematological malignancies. The 44th Annual ASH Meeting.
31. Chiriva-Internati M, Wang Z, Salati E, Lim S. Sperm protein 17 (Sp17) as a tumor vaccine for multiple myeloma. The 44th ASH Annual Meeting.
32. Lim S, Zhang Y, Chiriva-Internati M, Wang Z, Esler W, Townsend M, Smith P, Burris C, Klug P. Towards a chemotherapy-free outpatient transplant regimen. The 44th Annual ASH Meeting.
33. Lim S, Zhang Y, Chiriva-Internati M, Wang Z, Esler W, Townsend M, Smith P, Burris C, Klug P. A Phase I/II study of rituxan (CD20 antibody) maintenance therapy following high dose melphalan and autologous host for multiple myeloma. The 44th Annual ASH Meeting.
34. Chiriva-Internati M, Wang Z, Salati E, Lim S. Mapping. The CTL epitope of a novel CT antigen, sperm protein17 (sp17), restricted by HLA-A1. The 44th ASH Annual Meeting.
35. Grizzi F, Franceschini B, Chiriva-Internati M, Monti M, Dioguardi N. Sperm protein 17 is a new marker of melanophages in skin cancer. American Association of Immunology’s 90th Anniversary Annual Meeting.
36. Chiriva-Internati M, Liu Y, Grizzi F, Luo R, Klimberg S, Dioguardi N, Hermonat PL. An autoimmune-depleted HCV core gene gives cytotoxic T cell response upon AAV vector delivery into dendritic cells. American Association of Immunology’s 90th Anniversary Annual Meeting.
37. Chiriva-Internati M, Liu Y, Weidanz J, Grizzi F, Zhou W, Tricot G, Barlogie B, Hermonat PL. Stringent testing of adeno-associated virus-gene loading of dendritic cells for generating cytotoxic T lymphocytes against a prototype auto-antigen, multiple myeloma HM1.24. American Association of Immunology, 90th Anniversary Annual Meeting.
38. Chiriva-Internati M, Grizzi F, Hermonat PL, Liu Y, Muzzio PC. Effects of irradiation on the expression of major histocompatibility complex (MHC) and co-stimulation molecules in human multiple myeloma. American Association of Immunology 90th Anniversary Annual Meeting.
39. Grizzi F, Franceschini B, Chiriva-Internati M, Monti M, Dioguardi N. Mast cell and human hepatocarcinoma. Annual Digestive Disease Week.
40. Weidanz J, Wittman V, Thekkumkara T, Chiriva-Internati M. Angiotensin II regulates IFN-gamma production in human CTL line. 2nd Annual School of Pharmacy “Research Days".
41. Weidanz J, Wittman V, Thekkumkara T, Chiriva-Internati M. Angiotensin II as a modulator of T cell proliferation. 2nd Annual School of Pharmacy “Research Days”.
42. Chiriva-Internati M, Shah G. Targeted over expression of pituitary calcitonin in gonadotrophs of female transgenic mice induces a down regulation of T cells and monocytes, but up regulation of B cells. The Endocrine Society’s 85th Annual Meeting.
43. Hermonat PL, Liu Y, Grizzi F, Wan W, Tedesco A, Chiriva-Internati M. Recombinant Adeno-Associated Virus Expressing Sperm Protein 17 into Dendritic Cells Induce a Better Cancer Vaccine by Improving Generation of Anti-Sperm Protein 17-Specific Cytotoxic T-Lymphocytes. 12th International Congress of Immunology and 4th Annual Conference of FOCIS.
44. Liu Y, Chiriva-Internati M, Mehta JL, Hermonat PL. Further advances in immuno-gene therapy against human papillomavirus by adeno-associated virus gene transfer into dendritic cells. 7Th Annual Meeting of the American Society of Gene Therapy.
45. You H, Agrawal N, Prasad CP, Zhan DJ, Chiriva-Internati M, Grizzi F, Kay H, Mehta JL, Liu Y, Hermonat PL. Initial characterization of a super-permissive cell line for adeno-associated virus (AAV): Microarray-intimated CK2 helps AAV replication. 7th Annual Meeting of the American Society of Gene Therapy.
46. Grizzi F, Chiriva-Internati M. Spatial complexity analysis of the hepatitis B virus infection on liver tissue sections, international conference: “Computational and Mathematical Population Dynamics,”. Computational and Mathematical Population Dynamics.
47. Grizzi F, Franceschini B, Gaetani P, Colombo P, Tancioni F, Di Ieva A, Rodriguez y Baena R, Dioguardi N, Chiriva-Internati M. Sperm protein 17 is expressed in primary human nervous system tumors and has a high incidence in female patients. International Workshop. “The cell cycle and cancer: basic research, applications in medicine and public awareness”.
48. Chiriva-Internati M, Hermonat PL, Grizzi F, Mehta LJ, Liu Y, Cobos E. Gene transfection of CTL to increase the killing by antigen and cytokine dual-gene delivery T cells using recombinant adeno-associated virus-gene loading. Genoa, International Workshop. “The cell cycle and cancer: basic research, applications in medicine and public awareness”.
49. Grizzi F, Franceschini B, Gaetani P, Tancioni F, Di Ieva A, Bollati A, Baena R, Dioguardi N, Chiriva-Internati M. Sperm protein 17 is expressed in a subclass of human nervous system tumors. 12th International Congress of Immunology and 4th Annual Conference of FOCIS.
50. Grizzi F, Franceschini B, Gaetani P, Tancioni F, Di Ieva A, Bollati A, Baena R, Dioguardi N, Chiriva-Internati M. Sperm protein 17 is expressed in a subclass of human nervous system tumors. 12th International Congress of Immunology and 4th Annual Conference of FOCIS.
51. Chiriva-Internati M, Liu Y, Grizzi F, Wan W, Franceschini B, Tedesco A, Dioguardi N, Hermonat PL. A dual autoimmune-domain depleted HCV core gene gives significant anti-core, yet lower anti-“self” cytotoxic T lymphocyte response, upon AAV vector delivery into dendritic cells. 12th United European Gastroenterology Week, Liver Disease-Best abstracts (Czech Republic).
52. Chiriva-Internati M, Wan W, Tedesco A, Grizzi F. Recombinant adeno-associated virus expressing a novel cancer testis into dendritic cells induces a better cancer vaccine in ovarian cancer. 3rd International Conference on Innate Immunity".
53. Chiriva-Internati M, Wan W, Tedesco A, Grizzi F, Cobos E, Hermonat P. Generation of Cycosporin A resistant anti-CMV specific cytotoxic T lymphocytes for transplant patients by dual gene delivery into T cells and dendritic cells by adeno-associated virus vectors. Third Annual AACR International Conference on Frontiers in Cancer Prevention Research.
54. Chiriva-Internati M, Wan W, Tedesco A, Grizzi F, Hermonat P. Rapid generation of cytotoxic T lymphocytes against ovarian specific antigen by recombinant adeno-associated virus-based gene loading of dendritic cells. Third Annual AACR International Conference on Frontiers in Cancer Prevention Research.
55. Hermonat P L, Liu Y, Grizzi F, Wan W, Tedesco A, Chiriva-Internati M. rAAV virus expressing Sperm protein 17 into dendritic cells induce a superior cancer vaccine by improving generation of anti-Sperm protein 17-specific cytotoxic T-lymphocytes in Ovarian cancer. XLVI Congresso Nazionale Della Societa' Italiana di Cancerologia.
56. Chiriva-Internati M, Wan W, Tedesco A, Grizzi F, Hermonat P. Further Advances in Immuno-Gene Therapy against Human Papillomavirus by Adeno-Associated Virus Gene Transfer into Dendritic Cells. The International Society for Biological Therapy of Cancer (iSBTc) 19th Annual Meeting.
57. Chiriva-Internati M, Wan W, Tedesco A, Grizzi F, Frezza EE, Cobos E, Hermonat P. AAV vector-loading DC with an autoimmune domain-depleted HCV core gene stimulates high anti-core and low anti-self CTL. The International Society for Biological Therapy of Cancer 19th Annual Meeting.
58. Frezza EE, Grizzi F, Chiriva-Internati M. Immunological Treatment by gene manipulation for liver tumor. 4th International meeting on Hepatocellular Carcinoma: Eastern and Western Experiences.
59. Chiriva-Internati M, Grizzi F, Cobos E, Frezza EE. Spanx/ (ctp11) cancer/testis-associated genes family as possible tumor vaccine for liver neoplasia. Translational Immunology Related to Cancer Conference.
60. Chiriva-Internati M, Grizzi F, Austin KA, Shearer MH, Lowe DB, Kennedy RC. The development of murine tumor animal models for ovarian cancer incorporating a tumor specific sperm 17/cancer testis antigen. The International Society for Biological Therapy of Cancer (iSBTc) 20th Annual Meeting.
61. Bumm K, Chiriva-Internati M, Grizzi F, Kast WM, Koch H. Iro Sp17 Expression als Indikator für die Metastasierungstendenz von Ästhesioneuroblastomen Deutscher HNO Kongress Erfurt, HNO Informationen.
62. Frezza EE, Vizcarra JA, Wachtel MS, Chiriva-Internati M. The Multiple Faces of GLP-1, Obesity, Diabetes, Appetite, Stress. 2nd Cancer Drug Research and Development Conference.
63. Grizzi F, Russo C, Jumper C, Cobos E, Chiriva-Internati M, Dioguardi N, Muzzio PC. Computer-aided evaluation of lung parenchyma homogeneity in patients with chronic obstructive pulmonary disease. 1st World Congress of Thoracic Imaging.
64. Grizzi F, Russo C, Jumper C, Maggio D, Cobos E, Chiriva-Internati M, Dioguardi N, Muzzio P. Use and abuse of fractal geometry in pulmonary imaging. 1st World Congress of Thoracic Imaging,. 1st World Congress of Thoracic Imaging.
65. Chiriva-Internati M, Shah G. Targeted over expression of pituitary Calcitonin in gonadotrophs of female transgenic mice induces low functional activity of CD34 (+/-) derived dendritic cells. Gordon Research Conference on Molecular Pharmacology.
66. Frezza EE, Chiriva-Internati M. Cytoreduction in Liver Metastases by Radiofrequency Ablation (CRFA) Could this Increase the Survival?. European Association for the Study of the Liver.
67. Frezza EE, Chiriva-Internati M. Radiofrequency Ablation as a Method for Cytoreduction of Advanced Hepatocellular Carcinoma in Cirrhotic. European Association for the Study of the Liver.
68. Frezza EE, Chiriva-Internati M. The Role of Glucagon-Like Peptide-1 (GLP-1) in Non-Insulin Dependent Diabetes Mellitus (NIDDM) in MoDiseases. World Summit.
69. Frezza EE, Chiriva-Internati M. Cytoreduction in Liver Metastases by Radiofrequency Ablation (CRFA) Could this Increase the Survival?. European Association for the Study of the Liver.
70. Frezza EE, Chiriva-Internati M. Radiofrequency Ablation as a Method for Cytoreduction of Advanced Hepatocellular Carcinoma in Cirrhotic. European Association for the Study of the Liver.
71. Frezza EE, Chiriva-Internati M. Cytoreduction in Liver Metastases by Radiofrequency Ablation. 13th United European Gastroenterology Week.
72. Grizzi F, Chiriva-Internati M. Spatial complexity analysis of the hepatitis b virus infection on liver tissue sections. Gastro-Conference, Disease Progression and Disease Prevention in Hepatology and Gastroenterology.
73. Velez B, Grizzi F, Wan W, Pinkston J, D’Cunha N, Frezza EE, Cobos E, Kast WM, Ferrone S, Chiriva-Internati M. Tapasin and HLA class I down regulated in primary human multiple myeloma suitable indictor of poor prognosis. Southern Regional Meeting.
74. Grizzi F, Gaetani P, Franceschini B, Ceva-Grimaldi G, Dioguardi N, Frezza EE, Cobos E, Chiriva-Internati M. Sperm protein 17 is expressed in human nervous system tumors prevalently in female patients. Southern Regional Meeting.
75. Chiriva-Internati M, Chumbly K, Cobos E, Shah G. Possible model for autoimmune disease in pit-ct transgenic mice. Southern Regional Meeting.
76. Chiriva-Internati M, Grizzi F, Austin KA, Shearer MH, Lowe DB, Kennedy RC. The development of murine tumor animal models for ovarian cancer incorporating a tumor specific sperm 17/cancer testis antigen. Southern Regional Meeting.
77. Chiriva-Internati M, Pinkston J, Grizzi F, D’Cunha N, Cobos E. Radiation therapy potential to overcome tumor immune escape in multiple myeloma after standard treatment and bone marrow transplantation. Southern Regional Meeting.
78. Chiriva-Internati M, Ferrari R, Cobos E, Kast WM. Ropporin is a novel cancer testis antigens for multiple myeloma. Southern Regional Meetings.
79. Chiriva-Internati M, Ferrari R, Jenkins M, Cobos E, Kast WM. AKAP-associated sperm protein over-expression in ovarian cancer. Southern Regional Meetings.
80. Chiriva-Internati M, Ferrari R, Jenkins M, Cobos E, Kast WM. Cancer Testis Antigen (CTA): is AKAP-4 a novel CTA for Multiple Myeloma?. Southern Regional Meetings.
81. Chiriva-Internati M, Ferrari F, Prabhakar S, Cobos E. Sp17: a novel biomarker for early screening of prostate cancer patients. TXSAN.
82. Chiriva-Internati M, Ferrari R, Cobos E, Kast WM. PTTG-1: An Immunological Target for Multiple Myeloma. Southern Regional Meetings.
83. Chiriva-Internati M, Ferrari R, Jenkins M, Cobos E, Kast WM. Ropporin is a novel cancer testis antigen for multiple myeloma. American Association of Immunology’s 94th Anniversary Annual Meeting.
84. Wachtel M, Xu T, Zhang Y, Chiriva-Internati M, Frezza EE. Pancreas cancer survival can be precisely predicted by grade and stage. American College of Surgeons 93rd Annual Clinical Congress.
85. Chiriva-Internati M, Grizzi F, Cobos E, Frezza E. Immunological Treatment of Liver Tumors. American College of Surgeons 93rd Annual Clinical Congress.
86. Chiriva-Internati M, Frezza EE. Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinoma.
87. Wachtel M, Zhang Y, Kaye K, Chiriva-Internati M, Frezza EE. Increased age, male gender and cirrhosis, but not steatosis or a positive viral serology, negatively impact the life expectancy of patients who undergo liver biopsy. American College of Surgeons 93rd Annual Clinical Congress.
88. Ferrari R, Prabhakar M, Baglioni L, Borri M, Yu Y, Hyiari S, Moreno J, D’Cunha N, Hardwicke F, Gagliano N, Grizzi F, Frezza E, Cobos E, Chiriva-Internati M. AKAP-4 as biomarker for prostate cancer. Southern Regional Meetings and the Southern Society for Clinical Investigation (SSCI) annual meeting.
89. Chiriva-Internati M, Ferrari R, Yu Y, Baglioni L, Borri M, Chen B, D’Cunha N, Gagliano N, Grizzi F, Jenkins M, Frezza E, Cobos E. Sperm protein 17 is expressed in primary and metastatic breast cancer. Southern Regional Meetings and the Southern Society for Clinical Investigation (SSCI) annual meeting,.
90. Ferrari R, Prabhakar M, Baglioni L, Borri M, Yu Y, Hyiari S, Moreno J, D’Cunha N, Hardwicke F, Gagliano N, Grizzi F, Frezza E, Cobos E, Chiriva-Internati M. AKAP-4 as biomarker for prostate cancer. Southern Regional Meetings and the Southern Society for Clinical Investigation (SSCI) annual meeting.
91. Gagliano N, Chiriva-Internati M, Pluchino S, Costa F, Pettinari L, Moscheni C, Cossetti C, Ferrari R, Bassi R, Cobos E, Gioia M. Analysis of astrocyte-glioma interactions in a co-culture experimental model. Southern Regional Meetings and the Southern Society for Clinical Investigation (SSCI) annual meeting.
92. Chiriva-Internati M, Ferrari R, Yu Y, Baglioni L, Borri M, Chen B, D’Cunha N, Gagliano N, Grizzi F, Jenkins M, Frezza E, Cobos E. Sperm protein 17 is expressed in primary and metastatic breast cancer. Southern Regional Meetings and the Southern Society for Clinical Investigation (SSCI) annual meeting,.
93. Gagliano N, Chiriva-Internati M, Pluchino M, Costa F, Pettinari L, Cossetti C, Moscheni C, Bassi R, Cobos E, Gioia M. Characterization of astrocytes-glioma interaction in a co-colture experimental model. Meeting of the Federation of the European Connective Tissue Societies.
94. Chiriva-Internati M, Yu Y, Jenkins M, Cannon M, Chapman C, Cobos E, Kast WM. Sp17 Protein with CpG Immunization Induces an Active Immune Response Against Ovarian Cancer in the ID8 Animal Model. Vaccine Third Global Congress.
95. Cannon M, O’Brien T, Chiriva-Internati M. Dendritic cell redirection of regulatory T cell responses to ovarian cancer antigens. . 24th Annual meeting of the International Society for Biological Therapy of Cancer, October 2009.
96. Chiriva-Internati M, Yu Y, Jenkins M, Cannon M, Chapman C, Cobos E, Kast WM. Sperm protein 17 vaccination induces a long-term protective immune response against ovarian cancer. 24th Annual meeting of the International Society for Biological Therapy of Cancer.
97. Chiriva-Internati M, Yu Y, Jenkins M, Cannon M, Chapman C, Cobos E, Kast WM. Effective prevention and therapy of ovarian cancer with sperm protein 17 vaccination. 97th. Annual meeting of the American Association of Immunologists.
98. Mirandola L, Rea K, Larocca S, Comi P, Cobos E, Chiriva-Internati M, Chiaramonte M. Notch1 produces a deregulation of chemokine receptors expression and functions in hematological tumors. 1st World Congress on Controversies in Hematology (COHEM).
99. Mirandola L, Yi Y, Cannon MJ, Chapman C, Cobos E, Chiriva-Internati M. A paradigm shift in ovarian cancer immunotherapy: breaking immune tolerance redirecting T-helper differentiation with cancer/testis antigen vaccination. International Society for Biological Therapy of Cancer's (iSBTc) 25th Annual Meeting.
100. Mirandola L Apicella M, Colombo M, Carluccio S, Platonova N, Comi P, Cobos E, Kast M, Chiriva Internati M, Chiaramonte R. “Notch1 produces a deregulation of CXCR4/SDF1 chemokine signaling in multiple myeloma cells”. Immunology 2011 Meeting Abstract on The Journal of Immunology.
101. Yu Y, Mirandola L, Chui K, Jenkins M, Cobos E, John C, Chiriva-Internati M. (2011) Galectin-3C inhibits tumor growth and increases the anticancer activity of bortezomib in a murine model of human multiple myeloma. TTU/TTUHSC Post-doc day on April 22nd 2011 at the International Cultural Center TTU/TTUHSC.
102. Yu Y, Mirandola L, Chui K, Jenkins M, Cobos E, John C, Chiriva-Internati M. Galectin-3C inhibits tumor growth and increases the anticancer activity of bortezomib in a murine model of human multiple myeloma. 2nd Annual CPRIT Innovations in Cancer Prevention and Research Conference. Austin Convention Center.
103. Saadeh C, Wade R, Giridhar V, Mer J, Kim E, Figueroa A, D’Cunha R, Cobos C, Littlefield L, Yu Y, Moore M, Mirandola L, Jenkins M, Cobos E, Chiriva Internati M. Multiple Myeloma Biomarker Variation between Genders. 3rd Annual CPRIT Innovations in Cancer Prevention and Research Conference. Austin Convention Center.
104. Mirandola L, Chiaramonte R, Yu Y, Hardwick F, D'Cunha N, Lukman T, Nguyen D, Cobos E, Chiriva-Internati M. The cancer/testis antigens Ropporin and AKAP-4 are novel targets for multiple myeloma immunotherapy. SITC 27th Annual Meeting.
105. Konala V, Platonova N, Colombo M, Mirandola L, Lazzari E, Simone DD, Radhi S, Aulakh A, Zepeda K, Wade R, Mer J, Saadeh C, Yu Y, Jenkins M, Figueroa J, Cobos E, Chiriva-Internati M, Chiaramonte R. Relationship of the oncogene Notch and CXCR4/SDF1 signaling in human epithelial ovarian cancer. ASCO 2013 Annual Meeting.
106. Mirandola L, Chiriva-Internati M, Cobos E, Yu Y, Figueroa J, Garavelli S, Colombo M, Lazzari E, Platonova N, Zepeda K, Jumper C, Jenkins M, Alalawi R, Konala V, Aulakh A, Radhi S, Chiaramonte R. Chemokine receptors as novel targets of the oncogene Notch1 in acute lymphoblastic leukemia. ASCO 2013 Annual Meeting.
107. Chiriva-Internati M, Mirandola L, Lazzari E, Colombo M, Lancellotti M, Cobos E, Yu Y, Figueroa J, Saadeh C, Wade R, Zepeda K, Mer J, Konala V, Radhi R, Aulakh A, Jenkins M, Jumper J, Alalawi R, Chiaramonte R. Promotion of human multiple myeloma cell growth in vitro and bone marrow invasion in vivo by Notch receptors and the CXCR4/SDF1 axis. ASCO 2013 Annual Meeting.
108. Wade R, Radhi S, Chiriva-Internati M, Hardwick F, Mer J, Aulakh A, Saadeh C, Yu Y, Mirandola M, Zepeda K, Chiaramonte R, Colombo M, Platonova N, Nguyen DD, D’Chuna N, Konala V, Jenkins M, Figueroa J, Cobos E. The impact of sex on ropporin expression in multiple myeloma patients. ASCO 2013 Annual Meeting.
109. Chiriva-Internati M, Mirandola M, Yu Y, Jenkins M, Figueroa J, Cobos E. Cancer Testis Antigens Expression: Sex and Multiple Myeloma. 15th INTERNATIONAL CONGRESS OF IMMUNOLOGY.
110. Chiriva-Internati M, Mirandola L, Yu Y, Hardwicke F, D’Cunha N, Tijani L, Nguyen DD, Figueroa J, Cobos E. Cancer Treatment and diagnosis using cancer testis antigens for multiple myeloma. Expression: Sex and Multiple Myeloma. 15th INTERNATIONAL CONGRESS OF IMMUNOLOGY.
111. Chiriva-Internati M, Mirandola M, Leffers N, Hamrick C, Jenkins M, Cobos E, Nijman H, Kast WM. Combination of SP17 with CA125 serologic measurement for detection of ovarian cancer. AACR Frontiers in Cancer Prevention Research Conference.
112. Chiriva-Internati M, Mirandola L, Daver N, Ruvolo P, Yang J, Figueroa JA. New therapy for multiple-myeloma targeting Galectin-3 potentiates proteasome inhibitor efficacy and reduces their toxicity. The American Association of Immunologists, 2017 Meeting.
113. Chiriva-Internati M, Mirandola L, Figueroa JA, Grizzi F, Nguyen DD. SP17 is a new immunological target in triple-negative breast cancer. The American Association of Immunologists, 2017 Meeting.
114. Gagliano N, C Moscheni C, Tartaglia GM, Selleri S, Chiriva-Internati M, Cobos E, Torri C, Costa F, Pettinari F, Gioia M. Analysis of collagen turnover in healthy human gingival fibroblasts treated with different doses of tacrolimus. Southern Regional Meetings and the Southern Society for Clinical Investigation (SSCI) annual meeting.
115. Grizzi F, Chiriva-Internati M, N: D. Quantification of the pericellular membrane from dendritic cells. Ninth Annual International Conference of the Society for Chaos Theory in Psychology and Life Sciences.

Book Chapters

1. Figueroa AJ, Chiriva Internati M. Therapeutic Monoclonal Antibodies and Their Targets. Wiley Production_Biosimilars of Monoclonal Antibodies, 2017.
2. D'Souza M, Chiriva Internati M. Nanotechnology in Vaccine Delivery. Springer International Publishing Switzerland, 2014.
3. D’Souza M, Chiriva Internati M. Trends in non-parenteral delivery of biologics, vaccines and cancer. In: Trends in non-parenteral delivery of biologics, vaccines and cancer. Manmohan Singh and Maya Salnikova (Novartis), 2014.
4. Chiriva Internati M, Yu Y. Targeting Galectin-3 Unveils the Complexity of Multiple Myeloma, 2013.
5. Chiriva Internati M, Kast WM. Clinical Perspectives in Cancer Vaccines for Hematological Diseases. In: Cancer Vaccines. Informa Healthcare, 2011.
6. Chiriva Internati M, Bernardini G. TOXICOLOGY OF ENGINEERED METAL NANOPARTICLES. John Wiley & Sons Ltd. 2009. John Wiley & Sons Ltd, 2009.
7. Chiriva Internati M, Raj PP. Tumor Immunology and Cancer Related Bone Pain. In: Pain Medicine, 2005.
8. Chiriva Internati M. Estimate of Neovascular Tree Complexity by Microscopy Analysis. In: Science, Technology and Education of Microscopy: an Overview, Vol. II. Ed. Formatex, Spain, 2004. In: Estimate of Neovascular Tree Complexity by Microscopy Analysis. Formatex, Spain, 2004.
9. Chiriva Internati M. Recombinant Adeno-Associated Virus Expressing Sperm Protein 17 into Dendritic Cells Induce a Better Cancer Vaccine by Improving Generation of Anti-Sperm Protein 17-Specific Cytotoxic T-Lymphocytes. In: Immunology. Monduzzi, Editor, 2004.
10. Chiriva Internati M, Grizzi F. Sperm protein 17 is expressed in a subclass of human nervous system tumors. In: Immunology. Monduzzi, 2004.
11. Chiriva Internati M, Grizzi F. From Discovery to the Clinical Application In Nervo System Neoplasia. Monduzzi, 2004.
12. Chiriva Internati M, Grizzi F, Hermonat P. The Complexity and Microscopy in the Biological Sciences. In: Edition on Science and Technology of Microscopy, an Overview, Vol. I. Ed. Formatex, Spain, 2003. In: Edition on Science and Technology of Microscopy, an Overview, Vol. I. Ed. Formatex. Edition on Science and Technology of Microscopy, 2003.
13. Chiriva Internati M, Shah VG. Cancer cells and progrowth/prosurvival signaling. In: Encyclopedia of Hormones and Related Cell Regulators, Eds. Henry HL and Normon AW, Academic Press. New York, 2002. In: Encyclopedia of Hormones and Related Cell Regulators, Eds. Academic Press. New York, 2002, 2002.

Letters to the Editor

1. Grizzi F, Yiu D, Chiriva-Internati M, Taverna G. "Quantity," "Quality," and "Distribution Pattern" of Neovascular System: Is It the Time to Come Back to Aristotle Categories?. J Pediatr Orthop 41: e199, 2021.
2. Grizzi F, Qehajaj D, Yiu D, Bresalier RS, Chiriva-Internati M. PD-L1, fibrosis, and immunotherapy in hepatocellular carcinoma: the importance of a scientific method to explore observations and answer questions. Surg Today 50: 1318-1319, 2020.
3. Grizzi F, Chiriva-Internati M, Yiu D. On the assessment of angiogenesis: it is time to change (go further) from an estimate to a measurement. Folia Morphol (Warsz) 79: 188-189, 2020.
4. Grizzi F, Qehajaj D, Chiriva-Internati M, Stifter S. Comment on 'Tumour antigen expression in hepatocellular carcinoma in a low-endemic western area'. Br J Cancer 114: e1, 2016.
5. Grizzi F, Chiriva-Internati M. Translating sperm protein 17 as a target for immunotherapy from the bench to the bedside in the light of cancer complexity. Tissue Antigens 81: 116-8, 2013.
6. Chiriva-Internati M, Ferrari R, Yu Y, Hamrick C, Gagliano N, Grizzi F, Frezza E, Jenkins MR, Hardwick F, D'Cunha N, Kast WM, Cobos E. AKAP-4: a novel cancer testis antigen for multiple myeloma. Br J Haematol 140: 465-8, 2008.
7. Grizzi F, Franceschini B, Musardo S, Frezza EE, Cobos E, Chiriva-Internati M. Pituitary tumor transforming gene 1 in the liver. Hepatology 44: 1701-2, 2006.
8. Grizzi F, Franceschini B, Hermonat PL, Liu Y, Chiriva-Internati M. Some remarks on the somatic expression of sperm protein 17. Int J Cancer 111: 972-3; author reply 974, 2004.
9. Franceschini B, Grizzi F, Colombo P, Soda G, Bumm K, Hermonat PL, Monti M, Dioguardi N, Chiriva-Internati M. Expression of human sperm protein 17 in melanophages of cutaneous melanocytic lesions. Br J Dermatol 150: 780-2, 2004.
10. Chiriva-Internati M, Grizzi F, Franceschini B, Hermonat PL, Bright RK, Bumm K, Dioguardi N, Kast WM. Is sperm protein 17 a useful target for tumor immunotherapy?. Blood 102: 2308-9, 2003.
11. Grizzi F, Franceschini B, Chiriva-Internati M, Hermonat PL. Fractal tumor growth of ovarian cancer: sonographic evaluation. Gynecol Oncol 89: 552-3; author reply 554, 2003.
12. Grizzi F, Lim SH, Chiriva-Internati M, Franceschini B, Wang Z, Lawrence D, Dioguardi N. Sperm protein 17 is not expressed on normal leukocytes. Blood 99: 3479-80; author reply 3480-1, 2002.
13. Lim SH, Periman P, Klug P, Weidanz J, Whitton V, Chiriva-Internati M, Wang Z, Wright S. Defining tumor antigens: mRNA, protein or cytotoxicity?. Trends Immunol 23: 236-7; author reply 237-8, 2002.
14. Chiriva-Internati M, Grizzi F, Franceschini B, Hermonat PL, Lim S, Dioguardi N, Rodriguez FM. Expression of surface CD40 and immunocytochemical actin-bundling protein fascin in dendritic cells from multiple myeloma treated with retinoids during their differentiation in vitro. In Vitro Cell Dev Biol Anim 37: 641-3, 2001.
15. Grizzi F, Colombo P, Barbieri B, Franceschini B, Roncalli M, Chiriva-Internati M, Muzzio PC, Dioguardi N. Correspondence re: E. Sabo et al., Microscopic Analysis and Significance of Vascular Architectural Complexity in Renal Cell Carcinoma. Clin. Cancer Res., 7: 533-537, 2001. Clin Cancer Res 7: 3305-7, 2001.
16. Chiriva-Internati M, Grizzi F, Orbetegli O, Lim S, Hermonat PL, Dioguardi N. Expression of MHC and adhesion/costimulation molecules of dendritic cells from human blood during their differentiation in vitro. In Vitro Cell Dev Biol Anim 37: 177-9, 2001.
17. Grizzi F, Chiriva-Internati M. Fractal analysis. Gynecol Oncol 78: 78-80, 2000.

Patents

1. Chiriva Internati M. A method of producing genetically altered dendritic cells and the uses thereof. 2002. Patent Number: 09/634,952.
2. Chiriva Internati M. Methods for identifying and using disease associated antigens. Patent Number: WO/2020.243469.
3. Chiriva Internati M. , Sperm protein 17 for the diagnosis and treatment of cancer. 2008. Patent Number: 435/372.3.
4. Chiriva Internati M. Gene therapy vector system and methods of using same. 2007. Patent Number: 60/944,366,.