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      Mauro Di Pilato Image

      Mauro Di Pilato, Ph.D.

      Department of Immunology, Division of Discovery Science

      Present Title & Affiliation

      Primary Appointment

      Assistant Professor, Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX

      Dual/Joint/Adjunct Appointment

      Assistant Professor, Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX

      Education & Training

      Degree-Granting Education

      2015Universidad Autónoma de Madrid, Madrid, ES, Biochemistry, Molecular Biology, Biomedicine and Biotechnology, Ph.D
      2008Università degli Studi di Bari, Bari BA, IT, Medical Biotechnologies and Molecular Medicine, M.S
      2006Università degli Studi di Bari, Bari BA, IT, Health and Pharmaceutical Biotechnologies, BS

      Postgraduate Training

      2019-2020Research Fellowship, In vivo characterization of distinct neutrophil subtype responses after infection with vaccinia virus, IRB Bellinzona - Institute for Research in Biomedicine, Bellinzona
      2015-2019Research Fellowship, The role of Carma1 in regulatory T cells: from the homeostasis to the control of tumor response; and identifying the relevant target cells of anti-PD-1 cancer immunotherapy, Massachusetts General Hospital (MGH), Boston, Massachusetts
      2015-2015Research Fellowship, In vivo characterization of distinct neutrophil subtype responses after infection with Vaccinia virus, IRB Bellinzona - Institute for Research in Biomedicine, Bellinzona

      Honors & Awards

      2024Andrew Sabin Family Fellowship Award, The University of Texas MD Anderson Cancer Center
      2017Marie Curie Global Individual Fellowship
      2015European Molecular Biology Organization (EMBO) Long-Term Postdoctoral Fellowship
      2015Federation of European Biochemical Societies (FEBS) Short-Term Fellowship
      2010Ayudas Predoctoral de Formación en Investigación en Salud PhD (PFIS) Fellowship
      2009One of Fifty Winners of Leonardo da Vinci Scholarships Unipharma - Graduates 5

      Professional Memberships

      Immunology Program Steering Committee

      2025

      Gulf Coast Consortia-Immunology Steering

      2023

      Odyssey Fellowship Program

      2023

      Odyssey Outstanding Research Publication Award

      2022

      Graduate School of Biomedical Sciences (GSBS)

      2021

      Selected Presentations & Talks

      Local Presentations

      1. 2025. Harnessing CCR7⁺ Dendritic Cells for Enhanced Cancer Immunotherapy. Invited. Research Town Hall (RTH). Houston, Texas, US.
      2. 2025. Pinpointing the role of CCR7+ Dendritic Cells within tumor microenvironment. Invited. Mark Foundation Early Career Session. Houston, Texas, US.
      3. 2023. Odyssey Annual Retreat. Conference. Odyssey Annual Retreat. Houston, TX, US.
      4. 2023. Town Hall: “Our War on Cancer - from Junior Recruits”. Conference. Town Hall: “Our War on Cancer - from Junior Recruits”. Houston, TX, US.
      5. 2022. Monthly Melanoma Specialized Programs of Research Excellence (SPORE) Meetings. Conference. Monthly Melanoma Specialized Programs of Research Excellence (SPORE) Meetings. Houston, TX, US.
      6. 2022. Discovery Biomedicine Series. Conference. Discovery Biomedicine Series. Houston, TX, US.
      7. 2022. Cancer Center Support Grant (CCSG)/Molecular and Cellular Oncology (MCO) Distinguished Seminar Series. Conference. Cancer Center Support Grant (CCSG)/Molecular and Cellular Oncology (MCO) Distinguished Seminar Series. Houston, TX, US.
      8. 2021. Town Hall Research Highlights. Conference. Town Hall Research Highlights. Houston, TX, US.
      9. 2021. Cancer Biology Invited Speaker Series. Conference. Cancer Biology Invited Speaker Series. Houston, TX, US.
      10. 2021. Immunology Faculty Seminar Series. Conference. Immunology Faculty Seminar Series. Houston, TX, US.

      Regional Presentations

      1. 2025. Harnessing CCR7⁺ Dendritic Cells for Enhanced Cancer Immunotherapy. Invited. Houston, Texas, US.
      2. 2024. Dissecting tumor immune microenvironment: from A(PC) to T. Conference. Dissecting tumor immune microenvironment: from A(PC) to T, TX, US.
      3. 2023. Defining the Role of CCR7+ Dendritic Cells in Melanoma. Conference. Defining the Role of CCR7+ Dendritic Cells in Melanoma, US.
      4. 2023. Eliciting Anti-Tumor Immunity. Conference. Eliciting Anti-Tumor Immunity, US.
      5. 2023. CD83 A New ICB. Conference. CD83 A New ICB, US.
      6. 2023. CD83 A New ICB. Conference. CD83 A New ICB, US.
      7. 2023. Inter-Skin SPORE Monthly Webinar. Conference. Inter-Skin SPORE Monthly Webinar. Philadelphia, PA, US.

      National Presentations

      1. 2025. CD83 via CCR7+DC limits intratumoral CD8 responses and promotes tumor growth. Poster. Honolulu, Hawaii, US.

      International Presentations

      1. 2025. Harnessing CCR7⁺ Dendritic Cells for Enhanced Cancer Immunotherapy. Invited. Young Investigators Meeting, ES.
      2. 2024. International Seminar. Invited. International Seminar. Mexico City, MX.
      3. 2024. International Seminar. Invited. International Seminar. Frankfurt am Main, DE.
      4. 2022. International Seminar. Conference. International Seminar. Brescia, IT.
      Read More
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      Grant & Contract Support

      Date: 2027 - 2032
      Title:Chromosome 6q Shallow Deletion as a Biomarker of Response to Immunotherapy Across Tumors
      Funding Source:NIH
      Role:Collaborator
      ID:1 R01 CA311232 - 01A1
      Date: 2027 - 2032
      Title:Copy Number Directionality Defines Distinct Transcriptional and Immune Visible Versus Immune Evasive States in Colorectal Cancer
      Funding Source:NIH
      Role:Collaborator
      ID:FP00030229
      Date: 2027 - 2032
      Title:Defining the GITRL–GITR Axis Between CCR7⁺ Dendritic Cells and Regulatory T Cells in the Tumor Microenvironment
      Funding Source:NIH
      Role:PI
      ID:FP00030710
      Date: 2027 - 2031
      Title:Overcoming ICB Resistance: CD83 as a Novel Therapeutic Target
      Funding Source:American Cancer Society
      Role:PI
      ID:1 R21 CA323878 - 01
      Date: 2026 - 2031
      Title:Dissecting WRAD Core Function in DNA Replication and Tumor Immune Editing in Pancreatic Cancer
      Funding Source:National Cancer Institute
      Role:Collaborator
      ID:1 R01 CA 319385 - 01
      Date: 2026 - 2029
      Title:Targeting CD83 to Overcome Resistance to Immune Checkpoint Blockade in Tumors
      Funding Source:Cancer Prevention and Research Institute of Texas
      Role:PI
      ID:RP 270220
      Date: 2026 - 2029
      Title:Overcoming Resistance to Immune Checkpoint Blockade in Cancer by Targeting CD83
      Funding Source:Pershing Square Foundation
      Role:PI
      ID:FP00028470
      Date: 2026 - 2028
      Title:Overcoming Resistance to Immune Checkpoint Blockade in Cancer by Targeting CD83
      Funding Source:Concern Foundation
      Role:PI
      ID:FP00028521
      Date: 2026 - 2028
      Title:The Role of DFNB59 in GSDME-Mediated Pyroptosis
      Funding Source:NIH
      Role:PI
      ID:FP00028355
      Date: 2026 - 2027
      Title:Uncovering the Cell-Intrinsic and Environmental Sensing Machineries Governing CCR7+DC Anti-Tumoral Functions
      Funding Source:Swiss National Science Foundation
      Role:Mentor
      ID:FP00029220; Fund: 00018796
      Date: 2026 - 2029
      Title:Induction of Long-Lived Tumor-Reactive T Cell Responses for Breast Cancer Immunoprevention
      Funding Source:US Department of Defense (DoD)
      Role:Co-I
      ID:FP00027145
      Date: 2026 - 2031
      Title:CD83 Blockade: A Novel Strategy to Overcome Checkpoint Inhibitor Resistance in Tumors
      Funding Source:NIH
      Role:PI
      ID:FP00026789
      Date: 2026 - 2031
      Title:Chromosome 6q Shallow Deletion as a Biomarker of Response to Immunotherapy Across Tumors
      Funding Source:NIH
      Role:Collaborator
      ID:FP00026909
      Date: 2026 - 2030
      Title:Overcoming ICB Resistance: CD83 as a Novel Therapeutic Target
      Funding Source:American Cancer Society (ACS)
      Role:PI
      ID:FP00026699
      Date: 2026 - 2030
      Title:Exploring Cellular and Microenvironmental Perturbations Induced by Body Care Products during Melanomagenesis
      Funding Source:NIH
      Role:Co-I
      ID:FP00024465
      Date: 2025 - 2030
      Title:Deciphering the Role of CCR7+ Dendritic Cells Within Tumor Microenvironment
      Funding Source:NIH
      Role:PI
      ID:FP00025372
      Date: 2025 - 2028
      Title:Targeting CD83 to Overcome Resistance to Immune Checkpoint Blockade in Tumors
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:PI
      ID:RP 260242
      Date: 2025 - 2030
      Title:Deciphering the Role of CCR7+ dendritic Cells Within Tumor Microenvironment
      Funding Source:Howard Hughes Medical Institute (HHMI)
      Role:PI
      ID:FP00022834
      Date: 2025 - 2030
      Title:Tackling CD83 to Control Tumors Unresponsive to Conventional ICB
      Funding Source:NIH
      Role:PI
      ID:FP00023787
      Date: 2025 - 2030
      Title:Chromosome 6q Shallow Deletion as a Biomarker of Response to Immunotherapy Across Tumors
      Funding Source:V FOUNDATION
      Role:Collaborator
      ID:FP00025910
      Date: 2025 - 2030
      Title:Targeting Immunosuppression in Colorectal Cancer Minimal Residual Disease
      Funding Source:NIH
      Role:Collaborator
      ID:1R01 CA303030-01
      Date: 2025 - 2028
      Title:Exploring Cellular and Microenvironmental Perturbations Induced by Body Care Products During Melanomagenesis
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:Co-PI
      ID:RP 250335
      Date: 2024 - 2029
      Title:The Functional and Biochemical Characterization of the WRAD Core in Safeguarding Genome Stability in Pancreatic Cancer
      Funding Source:NIH/NCI
      Role:Collaborator
      ID:1 R01 CA296182-01
      Date: 2024 - 2026
      Title:Defining the Intratumoral Role of CCR7+ Dendritic Cells
      Funding Source:Andrew Sabin Family Fellows Program
      Role:PI
      ID:RCTS 00063741; Fund: 129132
      Date: 2024 - 2027
      Title:A Novel Mechanism Safeguards Anti-tumor Pyroptosis
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:Collaborator
      ID:RP 240252
      Date: 2023 - 2026
      Title:Define the Intratumoral Role of CCR7+ Dendritic Cells
      Funding Source:Life Sciences Research Foundation
      Role:Mentor
      ID:FP00017795
      Date: 2023 - 2024
      Title:Defining the Intratumoral role and infiltration of CCR7+ dendritic cells
      Funding Source:The University of Texas MD Anderson Cancer Center – Melanoma SPORE - Developmental Research Program (DRP)
      Role:PI
      ID:Fund: 128333
      Date: 2023 - 2026
      Title:Mapping the Geospatial Tumor Clonal Architecture to Restore Immune Recognition in Pancreatic Cancer
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:Co-I
      ID:RP 230373
      Date: 2023 - 2024
      Title:Pinpointing the CCR7+ Dendritic Cells on the Tumor Map
      Funding Source:American Association of Immunologists (AAI)
      Role:PI
      ID:FP00017485; Project: 00015035
      Date: 2022 - 2024
      Title:Define the Intratumoral Role of CCR7+ Dendritic Cells
      Funding Source:The University of Texas MD Anderson Cancer Center - Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation
      Role:PI
      ID:FP00016322; Project: 00014277
      Date: 2022 - 2023
      Title:The University of Texas MD Anderson Cancer Center, CCSG New Faculty Award
      Funding Source:NIH/NCI
      Role:PI
      ID:5P30CA016672-46; Project: 00858074
      Date: 2022 - 2023
      Title:Pinpointing the CCR7+ Dendritic Cells on the Tumor Map
      Funding Source:The University of Texas MD Anderson Cancer Center – Melanoma SPORE - Developmental Research Program (DRP)
      Role:PI
      ID:Fund: 125122
      Date: 2021 - 2026
      Title:Start-Up Funds
      Funding Source:The University of Texas MD Anderson Cancer Center
      Role:PI
      ID:Fund: 123622
      Date: 2021 - 2024
      Title:UT System Rising STARs Award
      Funding Source:The University of Texas System
      Role:PI
      ID:Fund: 123545
      Date: 2021 - 2026
      Title:Start-Up Funds
      Funding Source:The University of Texas MD Anderson Cancer Center
      Role:PI
      ID:Fund: 123459
      Date: 2020 - 2025
      Title:Recruitment of First-Time Tenure-Track Faculty Members
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:PI
      ID:RR 210017; Project: 00012275

      Selected Publications

      Peer-Reviewed Articles

      1. Li, R, Yang, P, Di Pilato, M, Zhang, J, Flowers, CR, Shang, L, Li, Z. Accurate imputation of pathway-specific gene expression in spatial transcriptomics with PASTA. Nature communications 17(1), 2026. e-Pub 2026. PMID: 41397970.
      2. Citron F, Cecchetto L, Di Pilato M, Draetta G F. DPY30 is an epigenetic decoupler linking replication stress to immunoediting in pancreatic cancer. Cancer Research, 2026. e-Pub 2026. PMID: 41941748.
      3. Pulfer, A, Pizzagalli, DU, Segura, MP, Germic, N, Virgilio, T, Di Pilato, M, Carrillo Barbera, P, Palladino, E, Antonello, P, Thelen, M, Simon, HU, Krause, R, Gonzalez, SF. An in vivo microscopy dataset for the characterization of leukocyte death. Scientific Data 12(1), 2025. e-Pub 2025. PMID: 40204757.
      4. Pizzagalli D U, Carrillo-Barberà P, Di Pilato M, Gonzalez S F. Systematic analysis of immune cell motility leveraging the open intravital microscopy database Immunemap. EMBO J, 2025. e-Pub 2025. PMID: 41266653.
      5. Citron F, Ho IL, Balestrieri C, Liu Z, Yen EN, Cecchetto L, Perelli L, Zhang L, Castillo Montanez LA, Blazanin N, Dyke CA, Shah R, Attanasio S, Srinivasan S, Chen KC, Chen Z, Scognamiglio I, Pham N, Khan H, Jiang S, Pan J, Vanderkruk B, Leung C, Mattohti M, Rai K, Chu Y, Wang L, Gao S, Deem AK, Carugo A, Wang H, Yao W, Tonon G, Xiong Y, Lorenzi PL, Bonini C, Zal A, Hoffman B, Giuliani V, Heffernan T, Jeter CR, Lissanu Y, Genovese G, Di Pilato M, Viale A, Draetta GF. WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer. bioRxiv, 2025. e-Pub 2025. PMID: 39484624.
      6. Di Pilato M, Gao Y, Sun Y, Fu A, Grass C, Seeholzer T, Feederle R, Mazo I, Kazer SW, Litchfield K, von Andrian UH, Mempel TR, Jenkins RW, Krappmann D, Keller P. Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer. J Immunother Precis Oncol 6(2):61-73, 2023. e-Pub 2023. PMID: 37214210.
      7. Ozga AJ, Chow MT, Lopes ME, Servis RL, Di Pilato M, Dehio P, Lian J, Mempel TR, Luster AD. CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection. Immunity 55(1):82-97, 2022. e-Pub 2022. PMID: 34847356.
      8. Crainiciuc G, Palomino-Segura M, Molina-Moreno M, Sicilia J, Aragones DG, Li JLY, Madurga R, Adrover JM, Aroca-Crevillén A, Martin-Salamanca S, Del Valle AS, Castillo SD, Welch HCE, Soehnlein O, Graupera M, Sánchez-Cabo F, Zarbock A, Smithgall TE, Di Pilato M, Mempel TR, Tharaux PL, González SF, Ayuso-Sacido A, Ng LG, Calvo GF, González-Díaz I, Díaz-de-María F, Hidalgo A. Behavioural immune landscapes of inflammation. Nature 601(7893):415-421, 2022. e-Pub 2022. PMID: 34987220.
      9. Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha BL, Dantes Z, Rataj F, Dorman K, Lutz J, Karches CH, Heise C, Kurzay M, Larimer BM, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth C, Benmebarek MR, Dhoqina D, Grünmeier R, Seifert M, Oener A, Ö U, Joaquina S, Vimeux L, Tran T, Hank T, Baba T, Huynh D, Megens RTA, Janssen KP, Jastroch M, Lamp D, Ruehland S, Di Pilato M, Pruessmann JN, Thomas M, Marr C, Ormanns S, Reischer A, Hristov M, Tartour E, Donnadieu E, Rothenfusser S, Duewell P, König LM, Schnurr M, Subklewe M, Liss AS, Halama N, Reichert M, Mempel TR, Endres S, Kobold S. T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nat Biomed Eng 5(11):1246-1260, 2021. e-Pub 2021. PMID: 34083764.
      10. Di Pilato M, Kfuri-Rubens R, Pruessmann JN, Ozga AJ, Messemaker M, Cadilha BL, Sivakumar R, Cianciaruso C, Warner RD, Marangoni F, Carrizosa E, Lesch S, Billingsley J, Perez-Ramos D, Zavala F, Rheinbay E, Luster AD, Gerner MY, Kobold S, Pittet MJ, Mempel TR. CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment. Cell 184(17):4512-4530.e22, 2021. e-Pub 2021. PMID: 34343496.
      11. Marangoni F, Zhakyp A, Corsini M, Geels SN, Carrizosa E, Thelen M, Mani V, Prüßmann JN, Warner RD, Ozga AJ, Di Pilato M, Othy S, Mempel TR. Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop. Cell 184(15):3998-4015.e19, 2021. e-Pub 2021. PMID: 34157302.
      12. Cadilha BL, Benmebarek MR, Dorman K, Oner A, Lorenzini T, Obeck H, Vänttinen M, Di Pilato M, Pruessmann JN, Stoiber S, Huynh D, Märkl F, Seifert M, Manske K, Suarez-Gosalvez J, Zeng Y, Lesch S, Karches CH, Heise C, Gottschlich A, Thomas M, Marr C, Zhang J, Pandey D, Feuchtinger T, Subklewe M, Mempel TR, Endres S, Kobold S. Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors. Sci Adv 7(24):eabi5781, 2021. e-Pub 2021. PMID: 34108220.
      13. Di Pilato M, Palomino-Segura M, Mejías-Pérez E, Gómez CE, Rubio-Ponce A, D'Antuono R, Pizzagalli DU, Pérez P, Kfuri-Rubens R, Benguría A, Dopazo A, Ballesteros I, Sorzano COS, Hidalgo A, Esteban M, Gonzalez SF. Neutrophil subtypes shape HIV-specific CD8 T-cell responses after vaccinia virus infection. NPJ Vaccines 6(1):52, 2021. e-Pub 2021. PMID: 33846352.
      14. Pérez P, Marín MQ, Lázaro-Frías A, CÓS S, Di Pilato M, Gómez CE, Esteban M, García-Arriaza J. An MVA Vector Expressing HIV-1 Envelope under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design. Vaccines (Basel) 7(4):208, 2019. e-Pub 2019. PMID: 31817622.
      15. Ligorio M, Sil S, Malagon-Lopez J, Nieman LT, Misale S, Di Pilato M, Ebright RY, Karabacak MN, Kulkarni AS, Liu A, Vincent Jordan N, Franses JW, Philipp J, Kreuzer J, Desai N, Arora KS, Rajurkar M, Horwitz E, Neyaz A, Tai E, Magnus NKC, Vo KD, Yashaswini CN, Marangoni F, Boukhali M, Fatherree JP, Damon LJ, Xega K, Desai R, Choz M, Bersani F, Langenbucher A, Thapar V, Morris R, Wellner UF, Schilling O, Lawrence MS, Liss AS, Rivera MN, Deshpande V, Benes CH, Maheswaran S, Haber DA, Fernandez-Del-Castillo C, Ferrone CR, Haas W, Aryee MJ, Ting DT. Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer. Cell 178(1):160-175.e27, 2019. e-Pub 2019. PMID: 31155233.
      16. Di Pilato M, Kim EY, Cadilha BL, Prüßmann JN, Nasrallah MN, Seruggia D, Usmani SM, Misale S, Zappulli V, Carrizosa E, Mani V, Ligorio M, Warner RD, Medoff BD, Marangoni F, Villani AC, Mempel TR. Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature 570(7759):112-116, 2019. e-Pub 2019. PMID: 31092922.
      17. Usmani SM, Murooka TT, Deruaz M, Koh WH, Sharaf RR, Di Pilato M, Power KA, Lopez P, Hnatiuk R, Vrbanac VD, Tager AM, Allen TM, Luster AD, Mempel TR. HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission. Cell Host Microbe 25(1):73-86.e5, 2019. e-Pub 2019. PMID: 30629922.
      18. Di Pilato M, Mejías-Pérez E, Sorzano COS, Esteban M. Distinct Roles of Vaccinia Virus NF-κB Inhibitor Proteins A52, B15, and K7 in the Immune Response. J Virol 91(13):e00575-17, 2017. e-Pub 2017. PMID: 28424281.
      19. Di Pilato M, Sánchez-Sampedro L, Mejías-Pérez E, Sorzano COS, Esteban M. Modification of promoter spacer length in vaccinia virus as a strategy to control the antigen expression. J Gen Virol 96(8):2360-2371, 2015. e-Pub 2015. PMID: 25972354.
      20. Di Pilato M, Mejías-Pérez E, Zonca M, Perdiguero B, Gómez CE, Trakala M, Nieto J, Nájera JL, Sorzano CO, Combadière C, Pantaleo G, Planelles L, Esteban M. NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses. Proc Natl Acad Sci U S A 112(11):E1333-42, 2015. e-Pub 2015. PMID: 25739961.
      21. Daszkiewicz L, Vázquez-Mateo C, Rackov G, Ballesteros-Tato A, Weber K, Madrigal-Avilés A, Di Pilato M, Fotedar A, Fotedar R, Flores JM, Esteban M, Martínez-A C, Balomenos D. Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production. Sci Rep 5:7691, 2015. e-Pub 2015. PMID: 25573673.
      22. Di Pilato M, Esteban M. Neutrophil and vaccine. Cell Cycle 14(11):1615-6, 2015. e-Pub 2015. PMID: 25927421.
      23. Di Pilato M, Mejías-Pérez E, Gómez CE, Perdiguero B, Sorzano COS, Esteban M. New vaccinia virus promoter as a potential candidate for future vaccines. J Gen Virol 94(Pt 12):2771-2776, 2013. e-Pub 2013. PMID: 24077296.
      24. Perdiguero B, Gómez CE, Di Pilato M, Sorzano CO, Delaloye J, Roger T, Calandra T, Pantaleo G, Esteban M. Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-C. PLoS One 8(9):e74831, 2013. e-Pub 2013. PMID: 24069354.

      Review Articles

      1. Pittet MJ, Di Pilato M, Garris C, Mempel TR. Dendritic cells as shepherds of T cell immunity in cancer. Immunity 56(10):2218-2230, 2023. e-Pub 2023. PMID: 37708889.
      2. Sánchez-Sampedro L, Perdiguero B, Mejías-Pérez E, García-Arriaza J, Di Pilato M, Esteban M. The evolution of poxvirus vaccines. Viruses 7(4):1726-803, 2015. e-Pub 2015. PMID: 25853483.

      Other Articles

      1. Jayabalan R, Gonzalez-Delgado R, Castillo Montanez L, Pan J, Kfuri-Rubens R, Li R, Chang J, Kugeratski F G, Islam S, Martínez Magdaleno J, Li J, Rankothgedera S, Zappulli V, Assmann V E, Rozario T J, Thian M, Wild A B, Trakala M, Steinkasserer A, Di Pilato M CD83 on CCR7+DC limits intratumoral CD8+ T cell infiltration and promotes tumor growth. Immunity.

      Patents

      1. Mempel TR, Di Pilato M. Targeting the CBM signalosome complex induces regulatory T cells to inflame the tumor microenvironment. Patent Number: WO/2019/133809.
      2. Mempel TR, Di Pilato M, von Andrian UH. Interval dosing of MALT1 inhibitors for optimal efficacy in combination with checkpoint inhibitors in cancer immunotherapy. Patent Number: 030258-095000PL01.
      Read More
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      CV information above last modified August 21, 2026

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