Rohtesh S Mehta, MD MPH MS
Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Stem Cell Transplantation, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2011 | University of Pittsburgh, Pittsburgh, PA, USA, MS, Clinical Trials |
| 2006 | University of North Texas Health Science Center, Fort Worth, TX, USA, MPH, Epidemiology |
| 2003 | Government Medical College, Patiala, IND, MD, Medicine & Surgery |
Postgraduate Training
| 2014-2015 | Clinical Fellowship, Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX |
| 2011-2014 | Clinical Fellowship, Hematology-Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA |
| 2006-2009 | Clinical Residency, Internal Medicine, Mercy Catholic Medical Center, Philadelphia, PA |
Board Certifications
| 2014 | American Board of Internal Medicine, Hematology |
| 2014 | American Board of Internal Medicine, Medical Oncology |
| 2010 | American Board of Internal Medicine, Hospice and Palliative Medicine |
| 2009 | American Board of Internal Medicine |
Experience & Service
Academic Appointments
Assistant Professor, Department of Stem Cell Transplantation, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2021
Honors & Awards
| 2009 | Best Resident Conference Award, PGY-III |
| 2009 | Best PGY-III Resident Award |
| 2009 | Daniel J. Hilferty Award for Clinical Excellence in Medicine |
| 2008 | Best PGY-II Resident Award |
| 2008 | Best Resident Conference Award, PGY-II |
| 2007 | Best PGY-I Intern Award |
| 2007 | Best Resident Research Award |
Selected Publications
Peer-Reviewed Articles
- Ragon BK, Mehta RS, Gulbis AM, Saliba RM, Chen J, Rondon G, Popat UR, Nieto Y, Oran B, Olson AL, Patel K, Hosing CM, Qazilbash MH, Shah N, Kebriaei P, Shpall EJ, Champlin RE, Alousi AM. Pentostatin therapy for steroid-refractory acute graft versus host disease: identifying those who may benefit. Bone Marrow Transplant 53(3):315-325, 2018. e-Pub 2017. PMID: 29269797.
- Mehta RS, Randolph B, Daher M, Rezvani K. NK cell therapy for hematologic malignancies. Int J Hematol 107(3):262-270, 2018. e-Pub 2018. PMID: 29383623.
- Hill L, Alousi A, Kebriaei P, Mehta R, Rezvani K, Shpall E. New and emerging therapies for acute and chronic graft versus host disease. Ther Adv Hematol 9(1):21-46, 2018. e-Pub 2017. PMID: 29317998.
- Mehta RS, Rezvani K. Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer. Front Immunol 9:283, 2018. e-Pub 2018. PMID: 29497427.
- Mehta RS, Cao Q, Holtan S, MacMillan ML, Weisdorf DJ. Upper GI GVHD: similar outcomes to other grade II graft-versus-host disease. Bone Marrow Transplant 52(52):1180-1186, 2017. e-Pub 2017. PMID: 28504665.
- Mehta RS, Saliba RM, Cao K, Kaur I, Rezvani K, Chen J, Olson A, Parmar S, Shah N, Marin D, Alousi A, Hosing C, Popat U, Kebriaei P, Champlin R, de Lima M, Skerrett D, Burke E, Shpall EJ, Oran B. Ex Vivo Mesenchymal Precursor Cell-Expanded Cord Blood Transplantation after Reduced-Intensity Conditioning Regimens Improves Time to Neutrophil Recovery. Biol Blood Marrow Transplant 23(8):1359-1366, 2017. e-Pub 2017. PMID: 28506845.
- Khoder A, Alsuliman A, Basar R, Sobieski C, Kondo K, Alousi AM, Szydlo R, Muftuoglu M, Shaim H, Apperley JF, Gokdemir E, Cooper N, Mehta RS, Marin D, Champlin R, Shpall E, Rezvani K. Evidence for B Cell Exhaustion in Chronic Graft-versus-Host Disease. Front Immunol 8:1937, 2017. e-Pub 2018. PMID: 29375566.
- Stringaris K, Marin D, Barrett AJ, Hills R, Sobieski C, Cao K, Saltarrelli JG, Daher M, Shaim H, Smith N, Linch D, Gale R, Allen C, Sekine T, Mehta R, Champlin R, Shpall EJ, Kantarjian H, Garcia-Manero G, Rezvani K. KIR gene haplotype: an independent predictor of clinical outcome in MDS patients. Blood 128(24):2819-2823, 2016. e-Pub 2016. PMID: 27760759.
- Mehta RS, Rezvani K. Can we make a better match or mismatch with KIR genotyping?. Hematology Am Soc Hematol Educ Program 2016(1):106-118, 2016. PMID: 27913469.
- Mehta RS, Rezvani K. Immune reconstitution post allogeneic transplant and the impact of immune recovery on the risk of infection. Virulence 7(8):1-16, 2016. e-Pub 2016. PMID: 27385018.
- Sarvaria A, Basar R, Mehta RS, Shaim H, Muftuoglu M, Khoder A, Sekine T, Gokdemir E, Kondo K, Marin D, Daher M, Alousi AM, Alsuliman A, Liu E, Oran B, Olson A, Jones RB, Popat U, Hosing C, Champlin R, Shpall EJ, Rezvani K. IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation. Blood 128(10):1346-61, 2016. e-Pub 2016. PMID: 27439912.
- Mehta RS, Peffault de Latour R, DeFor TE, Robin M, Lazaryan A, Xhaard A, Bejanyan N, de Fontbrune FS, Arora M, Brunstein CG, Blazar BR, Weisdorf DJ, MacMillan ML, Socie G, Holtan SG. Improved graft-versus-host disease-free, relapse-free survival associated with bone marrow as the stem cell source in adults. Haematologica 101(6):764-72, 2016. e-Pub 2016. PMID: 27036159.
- Mehta RS, Saliba RM, Chen J, Rondon G, Hammerstrom AE, Alousi A, Qazilbash M, Bashir Q, Ahmed S, Popat U, Hosing C, Khouri I, Shpall EJ, Champlin RE, Ciurea SO. Post-transplantation cyclophosphamide versus conventional graft-versus-host disease prophylaxis in mismatched unrelated donor haematopoietic cell transplantation. Br J Haematol 173(3):444-55, 2016. e-Pub 2016. PMID: 26947769.
- Mehta RS, Chen X, Antony J, Boyiadzis M, Szabolcs P. Generating Peripheral Blood Derived Lymphocytes Reacting Against Autologous Primary AML Blasts. J Immunother 39(2):71-80, 2016. PMID: 26849076.
- Oran B, Cao K, Saliba RM, Rezvani K, de Lima M, Ahmed S, Hosing CM, Popat UR, Carmazzi Y, Kebriaei P, Nieto Y, Rondon G, Willis D, Shah N, Parmar S, Olson A, Moore B, Marin D, Mehta R, Fernández-Viña M, Champlin RE, Shpall EJ. Better allele-level matching improves transplant-related mortality after double cord blood transplantation. Haematologica 100(10):1361-70, 2015. e-Pub 2015. PMID: 26250579.
- Saliba RM, Rezvani K, Leen A, Jorgensen J, Shah N, Hosing C, Parmar S, Oran B, Olson A, Rondon G, Chen J, Martinez C, Hamdi A, Mehta RS, Chemaly RF, Saunders IM, Bollard CM, Shpall EJ. General and Virus-Specific Immune Cell Reconstitution after Double Cord Blood Transplantation. Biol Blood Marrow Transplant 21(7):1284-90, 2015. e-Pub 2015. PMID: 25708219.
- Popat U, Mehta RS, Rezvani K, Fox P, Kondo K, Marin D, McNiece I, Oran B, Hosing C, Olson A, Parmar S, Shah N, Andreeff M, Kebriaei P, Kaur I, Yvon E, de Lima M, Cooper LJ, Tewari P, Champlin RE, Nieto Y, Andersson BS, Alousi A, Jones RB, Qazilbash MH, Bashir Q, Ciurea S, Ahmed S, Anderlini P, Bosque D, Bollard C, Molldrem JJ, Chen J, Rondon G, Thomas M, Miller L, Wolpe S, Simmons P, Robinson S, Zweidler-McKay PA, Shpall EJ. Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation. Blood 125(19):2885-92, 2015. e-Pub 2015. PMID: 25778529.
- Mehta RS, Rezvani K, Olson A, Oran B, Hosing C, Shah N, Parmar S, Armitage S, Shpall EJ. Novel Techniques for Ex Vivo Expansion of Cord Blood: Clinical Trials. Front Med (Lausanne) 2:89, 2015. e-Pub 2015. PMID: 26697430.
- Mehta RS, Shpall EJ, Rezvani K. Cord Blood as a Source of Natural Killer Cells. Front Med (Lausanne) 2:93, 2015. e-Pub 2016. PMID: 26779484.
- Mehta RS, Di Stasi A, Hosing C, Shah N, Rezvani K, Alousi A, O'Brien S, Wierda W, Keating M, Shpall EJ. Lenalidomide-induced graft-vs.-Leukemia effect in a patient with chronic lymphocytic leukemia who relapsed after allogeneic stem cell transplant. Clin Lymphoma Myeloma Leuk 14(3):e105-9, 2014. e-Pub 2013. PMID: 24502832.
- Mehta RS, Di Stasi A, Andersson BS, Nieto Y, Jones R, de Lima M, Hosing C, Popat U, Kebriaei P, Oran B, Alousi A, Rezvani K, Qazilbash M, Bashir Q, Bollard C, Cooper L, Worth L, Tewari P, McNiece I, Willhelm K, Champlin R, Shpall EJ. The development of a myeloablative, reduced-toxicity, conditioning regimen for cord blood transplantation. Clin Lymphoma Myeloma Leuk 14(1):e1-5, 2014. e-Pub 2013. PMID: 24169268.
- Mehta RS, Smith RE. Hemophagocytic lymphohistiocytosis (HLH): a review of literature. Med Oncol 30(4):740, 2013. e-Pub 2013. PMID: 24105023.
- Rollins-Raval M, Pillai R, Warita K, Mitsuhashi-Warita T, Mehta R, Boyiadzis M, Djokic M, Kant JA, Roth CG. CD123 immunohistochemical expression in acute myeloid leukemia is associated with underlying FLT3-ITD and NPM1 mutations. Appl Immunohistochem Mol Morphol 21(3):212-7, 2013. PMID: 22914610.
Abstracts
- Mehta RS, Holtan SG, Wang T, Hemmer MT, Spellman SR, Arora M, Couriel DR, Alousi AM, Pidala J, Weisdorf DJ. Graft-Versus-Host Disease (GVHD)-Free Relapse-Free Survival (GRFS) and Chronic Gvhd (CRFS) in Alternative Donor Hematopoietic Cell Transplantation (HCT) in Pediatric Patients. 59th ASH Annual Meeting and Exposition 130(Supplement 1):2053, 2017.
- Mehta RS, Holtan SG, Wang T, Hemmer T, Spellman SR, Arora M, Couriel DR, Alousi AM, Pidala J, Weisdorf DJ. Graft-Versus-Host Disease (GVHD)-Free Relapse-Free Survival (GRFS) and Chronic Gvhd (CRFS) in Alternative Donor Hematopoietic Cell Transplantation (HCT) in Adults. 59th ASH Annual Meeting and Exposition 130(Supplement 1):517, 2017.
Book Chapters
- Mehta RS, Weisdord D. History and Current Status of Hematopoietic Cell Transplantation. In: Hematopoietic Cell Transplantation for Malignant Conditions. Elsevier, 1-18, 2019.
- Mehta RS, Olson A, Ponce DM, Barker JN, Shpall EJ. Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies. In: Hematology, Basic Principles and Practice 7e, 2017.
- Mehta RS, Shpall EJ. Ex vivo Cord Blood Manipulation: Methods, Data and Challanges. In: Cord Blood Transplantations (Advances and Controversies in Hematopoietic Transplantation and Cell Therapy) 1st ed, 2017.
- Mehta RS, Brunstein C. Cord blood transplants versus other sources of allografts: Comparison of data in adult setting. In: Cord Blood Transplantations (Advances and Controversies in Hematopoietic Transplantation and Cell Therapy) 1st ed, 2017.
- Metha RS, Rezvani I, Shpall EJ. Expanded Umbilical Cord Cells. In: Current Concepts and Controversies in Hematopoietic Cell Transplantation, 2016.
- Mehta RS, Arnold R. Withholding and Withdrawing Life-Sustaining Therapies. In: Palliative Care: Core Skills and Clinical Competencies, 2nd Edition, 2011.