Mena Mansour, MBBCH
Department of Anatomical Pathology, Division of Pathology-Lab Medicine Div
About Dr. Mena Mansour
I am a surgical pathologist with fellowship training in head and neck pathology. My academic and clinical work has centered on advancing diagnostic accuracy and efficiency, particularly through digital pathology. In my previous role, I led the transition of the frozen section service to a fully digital platform, streamlining communication between pathologists and surgeons and significantly improving turnaround time, a model that gained institutional recognition.
My research is collaborative and translational, with published work in HPV-related cytology, salivary gland tumor immunophenotyping, thyroid cytology, and treatment response in squamous cell carcinoma.
I am passionate about education and mentorship and have worked closely with residents and fellows both at the microscope and in formal teaching roles.
I look forward to contributing to both the clinical and academic missions—expanding digital pathology efforts, fostering education, and continuing collaborative research that bridges technology and patient care.
Present Title & Affiliation
Primary Appointment
Associate Professor, Anatomical Pathology, Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2005 | University of Alexandria Faculty of Medicine, Alexandria, EG, Medicine, MBBCh |
Postgraduate Training
| 2017-2018 | Resident, Anatomic and Clinical Pathology, Icahn School of Medicine at Mount Sinai Hospital, New York, New York |
| 2016-2017 | Clinical Fellow, Endocrine, Head, and Neck Pathology Fellowship, Yale-New Haven Hospital, New Haven, Connecticut |
| 2015-2016 | Chief Resident, Pathology, Icahn School of Medicine at Mount Sinai Hospital, New York, New York |
| 2013-2016 | Resiudent, Anatomic and Clinical Pathology, Icahn School of Medicine at Mount Sinai Hospital, New York, New York |
| 2004-2005 | Rotating Intern, Multiple, University of Alexandria Faculty of Medicine, Alexandria |
Licenses & Certifications
| 2024 | Texas Medical License |
| 2018 | Illinois Medical License |
| 2018 | Missouri Medical License |
| 2018 | Pennsylvania Medical License |
| 2018 | Diplomate of the American Board of Pathology |
Experience & Service
Faculty Academic Appointments
Associate Professor, Pathology and Immunology, Anatomic Pathology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, 2023 - 2024
Assistant Professor, Pathology and Immunology, Anatomic Pathology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, 2018 - 2023
Administrative Appointments/Responsibilities
Director of Intraoperative Consultations at Barnes Jewish Hospital, Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, 2021 - 2024
Extramural Institutional Committee Activities
Junior Officer, Pathology Office of Faculty Development, Washington School of Medicine in St. Louis, 2021 - 2022
Member, Digital Pathology Steering Committee, Washington University School of Medicine in St. Louis, 2021 - 2024
Honors & Awards
| 2011 - Present | Travel Award, American Society of Virology |
| 2006 - Present | Certificate of Merit and Citizenship, Rotaract Mediterranean |
| 2004 - Present | Student Exchange Program Clinical Fellowship, University of Alexandria, Faculty of Medicine |
| 1998 - Present | Duke of Edinburgh Bronze International Award |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2026. Follicular Patterned Neoplasms, High-Grade, and Undifferentiated Carcinomas. Invited. Texas Society of Pathologists Conference. Dallas, Texas, US.
- 2024. Follicular Patterned Neoplasmsand WHO Updates. Invited. Missouri Society of Pathologists 2024 Conference. Saint Louis, Missouri, US.
Selected Publications
Peer-Reviewed Articles
- Irfan A, Chen IY, Stamou C, Hurlimann S, Rordorf T, Freiberger S, Irfan H, Rupp N, Mansour M. Distant Pulmonary Metastasis in Microsecretory Adenocarcinoma of the Salivary Gland: A Case Report Highlighting Histological Variation and Aggressive Potential. International Journal of Surgical Pathology 34(2):10668969251384841, 2025. e-Pub 2025. PMID: 41182975.
- Fournier I, Bandi AV, Hamidi S, Iyer P, Busaidy NL, Cabanillas ME, Dadu R, Hu MI, Waguespack SG, Basmaci UN, Williams MD, Mansour M, Monroe MG, Gross ND, Goepfert RP, Perrier ND, Banuchi V, Wang JR, Maniakas A, Zafereo ME. Management of Retropharyngeal Lymph Node Metastases in Thyroid Cancer. Head Neck 48(1):237-245, 2025. e-Pub 2025. PMID: 40891104.
- Tharakan, T, Puram, SV, Paniello, RC, Pipkorn, P, Zolkind, P, Harbison, RA, Adkins, D, Oppelt, P, Thorstad, W, Gay, HA, Apicelli, A, Moravan, M, Chernock, RD, Mansour, M, Ley, J, Jackson, RS. Patient-Reported Swallowing Outcomes in HPV+ Oropharyngeal Cancer by Postoperative Chemoradiation Dose in MINT and E3311. Otolaryngology - Head and Neck Surgery (United States) 173(2):410-419, 2025. e-Pub 2025. PMID: 40432516.
- Hamidi S, Maniakas A, Akhave NS, Banuchi VE, Busaidy NL, Dadu R, Ferrarotto R, Guise TA, Hofmann MC, Hosseini SM, Hu MI, Iyer PC, Mansour M, Marczyk VR, Roy-Chowdhuri S, Sherman SI, Sousa LG, Wang JR, Williams MD, Zafereo ME, Waguespack SG, Cabanillas ME. Characterization of advanced RAS-driven follicular-derived thyroid cancers and review of future therapeutic avenues. Journal of Clinical Endocrinology and Metabolism 111(2):471-483, 2025. e-Pub 2025. PMID: 40568752.
- Oliveira, G, Egloff, AM, Afeyan, AB, Wolff, JO, Zeng, Z, Chernock, RD, Zhou, L, Messier, C, Lizotte, PH, Pfaff, KL, Stromhaug, K, Penter, L, Haddad, RI, Hanna, GJ, Schoenfeld, JD, Goguen, L, Annino, DJ, Jo, VY, Oppelt, P, Pipkorn, P, Jackson, RS, Puram, SV, Paniello, RC, Rich, JT, Webb, J, Zevallos, JP, Mansour, M, Fu, J, Dunn, GP, Rodig, SJ, Ley, J, Morris, LG, Dunn, LA, Paweletz, CP, Kallogjeri, D, Piccirillo, JF, Adkins, D, Wu, C, Uppaluri, R. Preexisting tumor-resident T cells with cytotoxic potential associate with response to neoadjuvant anti-PD-1 in head and neck cancer. Science Immunology 8(87), 2023. e-Pub 2023. PMID: 37683037.
- Bishop, J, Thompson, LD, Siegele, B, Gagan, J, Mansour, M, Chernock, RD, Rooper, LM. Mucoepidermoid carcinoma may be devoid of squamoid cells by immunohistochemistry. Histopathology 82(2):305-313, 2023. e-Pub 2023. PMID: 36208053.
- Mahapatra, L, Lu, HC, Mansour, M, Byrnes, K. Discrepancies Between Clinical and Anatomic Causes of Death in Acute Invasive Fungal Sinusitis An Institutional Experience at a Tertiary Care Center. Archives of Pathology and Laboratory Medicine 146(10):1281-1285, 2022. e-Pub 2022. PMID: 35041753.
- Rooper LM, Mansour M, Yonescu R, Oliai BR, Bishop JA, Westra WH. The Decline of Salivary Adenocarcinoma Not Otherwise Specified as a Tumor Entity: Reclassification Using Contemporary Immunohistochemical Profiling and Diagnostic Criteria. Am J Surg Pathol 45(6):753-764, 2021. e-Pub 2021. PMID: 33284193.
- Lily Mahapatra, Mena M, Deyali Chatterjee, Dehner, Louis. Nodal Merkel Cell Carcinoma with Neuroblastoma Differentiation. AJSP: Reviews & Reports 26(4):e6-e9, 2021. e-Pub 2021.
- Andruska N, Mahapatra L, Brenneman RJ, Huang Y, Paniello RC, Puram SV, Mansour M, Rich JT, Baumann BC, Thorstad WL, Daly MD. Regional lymph node irradiation in locally advanced Merkel cell carcinoma reduces regional and distant relapse and improves disease-specific survival. Radiother Oncol 155:246-253, 2021. e-Pub 2021. PMID: 33212121.
- A Aggarwal, Mansour M. Primary Alveolar Soft Part Sarcoma Arising in the Thyroid Gland: A Rare Case Report. AJSP: Reviews and Reports 26(1):35-37, 2021. e-Pub 2021.
- El-Salem F, Mansour M, Gitman M, Miles BA, Posner MR, Bakst RL, Genden EM, Westra WH. Real-time PCR HPV genotyping in fine needle aspirations of metastatic head and neck squamous cell carcinoma: Exposing the limitations of conventional p16 immunostaining. Oral Oncol 90:74-79, 2019. e-Pub 2019. PMID: 30846180.
- Ramos I, Mansour M, Wohlbold TJ, Ermler ME, Hirsh A, Runstadler JA, Fernandez-Sesma A, Krammer F. Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus. Emerg Infect Dis 21(7):1197-201, 2015. e-Pub 2015. PMID: 26079843.
- Cuadrado-Castano S, Ayllon J, Mansour M, de la Iglesia-Vicente J, Jordan S, Tripathi S, Garcia-Sastre A, Villar E. Enhancement of the proapoptotic properties of newcastle disease virus promotes tumor remission in syngeneic murine cancer models. Mol Cancer Ther 14(5):1247-58, 2015. e-Pub 2015. PMID: 25761895.
- Zamarin D, Holmgaard RB, Subudhi SK, Park JS, Mansour M, Palese P, Merghoub T, Wolchok JD, Allison JP. Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy. Sci Transl Med 6(226):226ra32, 2014. e-Pub 2014. PMID: 24598590.
- Mansour M, Palese P, Zamarin D. Oncolytic specificity of Newcastle disease virus is mediated by selectivity for apoptosis-resistant cells. J Virol 85(12):6015-23, 2011. e-Pub 2011. PMID: 21471241.
- Zamarin D, Martinez-Sobrido L, Kelly K, Mansour M, Sheng G, Vigil A, Garcia-Sastre A, Palese P, Fong Y. Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses. Mol Ther 17(4):697-706, 2009. e-Pub 2009. PMID: 19209145.
- Cheng GZ, Zhang WZ, Sun M, Wang Q, Coppola D, Mansour M, Xu LM, Costanzo C, Cheng JQ, Wang LH. Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function. J Biol Chem 283(21):14665-73, 2008. e-Pub 2008. PMID: 18353781.
Review Articles
- Mansour M, Hernandez-Prera JC. Histopathology of Chronic Rhinosinusitis and Sinonasal Inflammatory Polyps. Head Neck Pathol 19(1):35, 2025. e-Pub 2025. PMID: 40088323.
- Hutchens, T, Mansour, M. Genetics in the endocrine system: the impact of the TRK family. Diagnostic Histopathology 28(7):313-320, 2022. e-Pub 2022.
- Gonxalez, Manuel Lora, Chernock, Rebecca D, Mansour M. Environmental factors and anatomic pathology of the thyroid gland: review of literature. Diagnostic Histopathology 25(5):313-320, 2020. e-Pub 2020.
Book Chapters
- Mansour M, Rebecca D Chernock. Larynx. In: The Washington Manual of Surgical Pathology. 3. Wolters Kluwer, 2019.
- Samir K. El-Mofty, Mansour M, Dikson Dibe Gondim. Nasal Cavity, Paranasal Sinuses, and Nasopharynx. In: The Washington Manual of Surgical Pathology. 3. Wolter Kluwer, 2019.
- Mansour M, Samir K El-Mofty. Tumors and Cysts of the Jaw. In: The Washington Manual of Surgical Pathology. 3. Wolter Kluwer, 2019.
Patient Reviews
CV information above last modified July 22, 2026