
Michael R. Green, Ph.D.
Department of Lymphoma - Myeloma, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Lymphoma/Myeloma - Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, Translational and Laboratory Research, Department of Lymphoma/Myeloma, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2009 | Griffith University, South East Queensland, AUS, PHD, Molecular Genetics |
2006 | Victoria University of Wellington, Wellington, NZL, BS, Cell and Molecular Biology |
2005 | Victoria University of Wellington, Wellington, NZL, BS, Human Genetics/Molecular Pathology |
Postgraduate Training
2011-2013 | Research Fellowship, Medical Oncology, Stanford University, Stanford, CA |
2009-2011 | Research Fellowship, Medical Oncology, Dana-Farber, Boston, MA |
Experience & Service
Academic Appointments
Assistant Professor, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, 2014 - 2017
Instructor, Division of Oncology, Stanford University School of Medicine, Stanford, CA, 2013 - 2014
Honors & Awards
2020 | Scholar Award, Leukemia and Lymphoma Society |
2020 | President’s Recognition of Faculty Excellence, Research, MD Anderson Cancer Center |
2020 | Sabin Family Foundation Fellow Award, MD Anderson Cancer Center |
2020 | 2020 Emil Frei III Award for Excellence in Translational Research, Division of Cancer Medicine. MD Anderson Cancer Center |
2017 | Rising STARS Award, University of Texas System |
2012 | Special Fellow Award, Leukemia and Lymphoma Society |
2012 | Abstract Achievement Award, American Society of Hematology |
2012 | Millennium Pharmaceuticals Fellowship, Lymphoma Research Foundation (Declined) |
2010 | Fellow Award, Leukemia and Lymphoma Society (Declined) |
2006 | Presenter Award, International Congress of Human Genetics |
2006 | Anthony Herbert Postgraduate Research Scholarship, Griffith University |
2006 | Griffith University Postgraduate Research Scholarship, Griffith University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Deng Q, Han G, Puebla-Osorio N, Ma MCJ, Strati P, Chasen B, Dai E, Dang M, Jain N, Yang H, Wang Y, Zhang S, Wang R, Chen R, Showell J, Ghosh S, Patchva S, Zhang Q, Sun R, Hagemeister F, Fayad L, Samaniego F, Lee HC, Nastoupil LJ, Fowler N, Eric Davis R, Westin J, Neelapu SS, Wang L, Green MR. Characteristics of anti-CD19 CAR T-cell infusion products associated with efficacy and toxicity in patients with large B-cell lymphomas. Nat Med, 2020. e-Pub 2020. PMID: 33020644.
- Swenson SA, Gilbreath TJ, Vahle H, Hynes-Smith RW, Graham JH, Law HC, Amador C, Woods NT, Green MR, Buckley SM. E3 Ligase, UBR5, HECT domain mutations in lymphoma control maturation of B cells. Blood 136(3):299-312, 2020. e-Pub 2020. PMID: 32325489.
- Strati P, Ahmed S, Kebriaei P, Nastoupil LJ, Claussen CM, Watson G, Horowitz SB, Brown ART, Do B, Rodriguez MA, Nair R, Shpall EJ, Green MR, Neelapu SS, Westin JR. Clinical efficacy of anakinra to mitigate CAR T-cell therapy-associated toxicity in large B-cell lymphoma. Blood Adv 4(13):3123-3127, 2020. PMID: 32645136.
- Venturutti L, Teater M, Zhai A, Chadburn A, Babiker L, Kim D, Béguelin W, Lee TC, Kim Y, Chin CR, Yewdell WT, Raught B, Phillip JM, Jiang Y, Staudt LM, Green MR, Chaudhuri J, Elemento O, Farinha P, Weng AP, Nissen MD, Steidl C, Morin RD, Scott DW, Privé GG, Melnick AM. TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell 182(2):297-316.e27, 2020. e-Pub 2020. PMID: 32619424.
- Green MR, Neelapu SS. Not So FASt: Tumor Cells Resisting Death Drive CAR T-cell Dysfunction. Cancer Discov 10(4):492-494, 2020. PMID: 32238396.
- Saenz DT, Fiskus W, Mill CP, Perera D, Manshouri T, Lara BH, Karkhanis V, Sharma S, Horrigan SK, Bose P, Kadia TM, Masarova L, DiNardo CD, Borthakur G, Khoury JD, Takahashi K, Bhaskara S, Lin CY, Green MR, Coarfa C, Crews CM, Verstovsek S, Bhalla KN. Mechanistic basis and efficacy of targeting the β-catenin-TCF7L2-JMJD6-c-Myc axis to overcome resistance to BET inhibitors. Blood 135(15):1255-1269, 2020. PMID: 32068780.
- Mondello P, Tadros S, Teater M, Fontan L, Chang AY, Jain N, Yang H, Singh S, Ying HY, Chu CS, Ma MCJ, Toska E, Alig S, Durant M, de Stanchina E, Ghosh S, Mottok A, Nastoupil L, Neelapu SS, Weigert O, Inghirami G, Baselga J, Younes A, Yee C, Dogan A, Scheinberg DA, Roeder RG, Melnick AM, Green MR. Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma. Cancer Discov, 2020. e-Pub 2020. PMID: 31915197.
- Mill CP, Fiskus W, DiNardo CD, Qian Y, Raina K, Rajapakshe K, Perera D, Coarfa C, Kadia TM, Khoury JD, Saenz DT, Saenz DN, Illendula A, Takahashi K, Kornblau SM, Green MR, Futreal AP, Bushweller JH, Crews CM, Bhalla KN. RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1. Blood 134(1):59-73, 2019. e-Pub 2019. PMID: 31023702.
- Li M, Chiang YL, Lyssiotis CA, Teater MR, Hong JY, Shen H, Wang L, Hu J, Jing H, Chen Z, Jain N, Duy C, Mistry SJ, Cerchietti L, Cross JR, Cantley LC, Green MR, Lin H, Melnick AM. Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis. Cancer Cell 35(6):916-931.e9, 2019. PMID: 31185214.
- Jain N, Hartert K, Tadros S, Fiskus W, Havranek O, Ma MCJ, Bouska A, Heavican T, Kumar D, Deng Q, Moore D, Pak C, Liu CL, Gentles AJ, Hartmann E, Kridel R, Smedby KE, Juliusson G, Rosenquist R, Gascoyne RD, Rosenwald A, Giancotti F, Neelapu SS, Westin J, Vose JM, Lunning MA, Greiner T, Rodig S, Iqbal J, Alizadeh AA, Davis RE, Bhalla K, Green MR. Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma. Sci Transl Med 11(497), 2019. PMID: 31217338.
- Becnel MR, Nastoupil LJ, Samaniego F, Davis RE, You MJ, Green M, Hagemeister FB, Fanale MA, Fayad LE, Westin JR, Wang M, Oki Y, Forbes SG, Feng L, Neelapu SS, Fowler NH. Lenalidomide plus rituximab (R2 ) in previously untreated marginal zone lymphoma: subgroup analysis and long-term follow-up of an open-label phase 2 trial. Br J Haematol 185(5):874-882, 2019. e-Pub 2019. PMID: 30919940.
- Wang S, Mondal S, Zhao C, Berishaj M, Ghanakota P, Batlevi CL, Dogan A, Seshan VE, Abel R, Green MR, Younes A, Wendel HG. Noncovalent inhibitors reveal BTK gatekeeper and auto-inhibitory residues that control its transforming activity. JCI Insight 4(12), 2019. e-Pub 2019. PMID: 31217352.
- Vicente-Dueñas C, González-Herrero I, Sehgal L, García-Ramírez I, Rodríguez-Hernández G, Pintado B, Blanco O, Criado FJG, Cenador MBG, Green MR, Sánchez-García I. Dnmt1 links BCR-ABLp210 to epigenetic tumor stem cell priming in myeloid leukemia. Leukemia 33(1):249-278, 2019. e-Pub 2018. PMID: 29955131.
- Dominguez PM, Ghamlouch H, Rosikiewicz W, Kumar P, Béguelin W, Fontán L, Rivas MA, Pawlikowska P, Armand M, Mouly E, Torres-Martin M, Doane AS, Calvo Fernandez MT, Durant M, Della-Valle V, Teater M, Cimmino L, Droin N, Tadros S, Motanagh S, Shih AH, Rubin MA, Tam W, Aifantis I, Levine RL, Elemento O, Inghirami G, Green MR, Figueroa ME, Bernard OA, Aoufouchi S, Li S, Shaknovich R, Melnick AM. TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis. Cancer Discov 8(12):1632-1653, 2018. e-Pub 2018. PMID: 30274972.
- Choi J, Lee K, Ingvarsdottir K, Bonasio R, Saraf A, Florens L, Washburn MP, Tadros S, Green MR, Busino L. Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2. Nat Cell Biol 20(May 2018):586-596, 2018. e-Pub 2018. PMID: 29695787.
- Keane C, Tobin J, Talaulikar D, Green M, Crooks P, Jain S, Gandhi M. A high LDH to absolute lymphocyte count ratio in patients with DLBCL predicts for a poor intratumoral immune response and inferior survival. Oncotarget 9(34):23620-23627, 2018. e-Pub 2018. PMID: 29805761.
- Kunder CA, Roncador G, Advani RH, Gualco G, Bacchi CE, Sabile JM, Lossos IS, Nie K, Tibshirani RJ, Green MR, Alizadeh AA, Natkunam Y. KLHL6 is preferentially expressed In germinal center-derived B-cell lymphomas. Am J Clin Pathol 148(6):465-476, 2017. e-Pub 2017. PMID: 29140403.
- García-Ramírez I, Tadros S, González-Herrero I, Martín-Lorenzo A, Rodríguez-Hernández G, Moore D, Ruiz-Roca L, Blanco O, Alonso-López D, Rivas JL, Hartert K, Duval R, Klinkebiel D, Bast M, Vose J, Lunning M, Fu K, Greiner T, Rodrigues-Lima F, Jiménez R, Criado FJG, Cenador MBG, Brindle P, Vicente-Dueñas C, Alizadeh A, Sánchez-García I, Green MR. Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice. Blood 129(19):2645-2656, 2017. e-Pub 2017. PMID: 28288979.
- Keane C, Gould C, Jones K, Hamm D, Talaulikar D, Ellis J, Vari F, Birch S, Han E, Wood P, Le-Cao KA, Green MR, Crooks P, Jain S, Tobin J, Steptoe RJ, Gandhi MK. The T-cell Receptor Repertoire Influences the Tumor Microenvironment and Is Associated with Survival in Aggressive B-cell Lymphoma. Clin Cancer Res 23(7):1820-1828, 2017. e-Pub 2016. PMID: 27649554.
- Khodadoust MS, Olsson N, Wagar LE, Haabeth OA, Chen B, Swaminathan K, Rawson K, Liu CL, Steiner D, Lund P, Rao S, Zhang L, Marceau C, Stehr H, Newman AM, Czerwinski DK, Carlton VE, Moorhead M, Faham M, Kohrt HE, Carette J, Green MR, Davis MM, Levy R, Elias JE, Alizadeh AA. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens. Nature 543(7647):723-727, 2017. e-Pub 2017. PMID: 28329770.
- Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, Wälchli S, Green MR, Trøen G, Liestøl K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R. Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling. Blood 129(6):759-770, 2017. e-Pub 2016. PMID: 28011673.
- Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican T, Lachel CM, Yu J, Ferro R, Eldorghamy N, Greiner TC, Vose J, Weisenburger DD, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, Jaffe ES, Braziel RM, Siebert R, Miles RR, Dave S, Reddy A, Delabie J, Staudt LM, Song JY, McKeithan TW, Fu K, Green M, Chan WC, Iqbal J. Adult High Grade B-cell Lymphoma with Burkitt Lymphoma Signature: Genomic features and Potential Therapeutic Targets. Blood, 2017. e-Pub 2017. PMID: 28801451.
- Rogozin IB, Lada AG, Goncearenco A, Green MR, De S, Nudelman G, Panchenko AR, Koonin EV, Pavlov YI. Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers. Sci Rep 6:38133, 2016. e-Pub 2016. PMID: 27924834.
- Keane C, Vari F, Hertzberg M, Cao KA, Green MR, Han E, Seymour JF, Hicks RJ, Gill D, Crooks P, Gould C, Jones K, Griffiths LR, Talaulikar D, Jain S, Tobin J, Gandhi MK. Ratios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study. Lancet Haematol 2(10):e445-55, 2015. e-Pub 2015. PMID: 26686046.
- Kurtz DM, Green MR, Bratman SV, Scherer F, Liu CL, Kunder CA, Takahashi K, Glover C, Keane C, Kihira S, Visser B, Callahan J, Kong KA, Faham M, Corbelli KS, Miklos D, Advani RH, Levy R, Hicks RJ, Hertzberg M, Ohgami RS, Gandhi MK, Diehn M, Alizadeh AA. Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing. Blood 125(24):3679-87, 2015. e-Pub 2015. PMID: 25887775.
- Newman AM, Liu CL, Green MR, Gentles AJ, Feng W, Xu Y, Hoang CD, Diehn M, Alizadeh AA. Robust enumeration of cell subsets from tissue expression profiles. Nat Methods 12(5):453-7, 2015. e-Pub 2015. PMID: 25822800.
- Green MR, Kihira S, Liu CL, Nair RV, Salari R, Gentles AJ, Irish J, Stehr H, Vicente-Dueñas C, Romero-Camarero I, Sanchez-Garcia I, Plevritis SK, Arber DA, Batzoglou S, Levy R, Alizadeh AA. Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation. Proc Natl Acad Sci U S A 112(10):E1116-25, 2015. e-Pub 2015. PMID: 25713363.
- Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sanchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I. Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma. Nat Commun 5:3904, 2014. e-Pub 2014. PMID: 24887457.
- Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R. Depleting tumor-specific Tregs at a single site eradicates disseminated tumors. J Clin Invest 123(6):2447-63, 2013. PMID: 23728179.
- Aya-Bonilla C, Green MR, Camilleri E, Benton M, Keane C, Marlton P, Lea R, Gandhi MK, Griffiths LR. High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to Non-Hodgkin's lymphoma. Genes Chromosomes Cancer 52(5):467-79, 2013. e-Pub 2013. PMID: 23341091.
- Myklebust JH, Irish JM, Brody J, Czerwinski DK, Houot R, Kohrt HE, Timmerman J, Said J, Green MR, Delabie J, Kolstad A, Alizadeh AA, Levy R. High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells. Blood 121(8):1367-76, 2013. e-Pub 2013. PMID: 23297127.
- Green MR, Gentles AJ, Nair RV, Irish JM, Kihira S, Liu CL, Kela I, Hopmans ES, Myklebust JH, Ji H, Plevritis SK, Levy R, Alizadeh AA. Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood 121(9):1604-11, 2013. e-Pub 2013. PMID: 23297126.
- Romero-Camarero I, Jiang X, Natkunam Y, Lu X, Vicente-Dueñas C, Gonzalez-Herrero I, Flores T, Garcia JL, McNamara G, Kunder C, Zhao S, Segura V, Fontan L, Martínez-Climent JA, García-Criado FJ, Theis JD, Dogan A, Campos-Sánchez E, Green MR, Alizadeh AA, Cobaleda C, Sánchez-García I, Lossos IS. Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation. Nat Commun 4:1338, 2013. PMID: 23299888.
- Caro P, Kishan AU, Norberg E, Stanley IA, Chapuy B, Ficarro SB, Polak K, Tondera D, Gounarides J, Yin H, Zhou F, Green MR, Chen L, Monti S, Marto JA, Shipp MA, Danial NN. Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell 22(4):547-60, 2012. PMID: 23079663.
- Green MR, Rodig S, Juszczynski P, Ouyang J, Sinha P, O'Donnell E, Neuberg D, Shipp MA. Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy. Clin Cancer Res 18(6):1611-8, 2012. e-Pub 2012. PMID: 22271878.
- Green MR, Camilleri E, Gandhi MK, Peake J, Griffiths LR. A novel immunodeficiency disorder characterized by genetic amplification of interleukin 25. Genes Immun 12(8):663-6, 2011. e-Pub 2011. PMID: 21776014.
- Kondratiev S, Duraisamy S, Unitt CL, Green MR, Pinkus GS, Shipp MA, Kutok JL, Drapkin RI, Rodig SJ. Aberrant expression of the dendritic cell marker TNFAIP2 by the malignant cells of Hodgkin lymphoma and primary mediastinal large B-cell lymphoma distinguishes these tumor types from morphologically and phenotypically similar lymphomas. Am J Surg Pathol 35(10):1531-9, 2011. PMID: 21921781.
- Green MR, Aya-Bonilla C, Gandhi MK, Lea RA, Wellwood J, Wood P, Marlton P, Griffiths LR. Integrative genomic profiling reveals conserved genetic mechanisms for tumorigenesis in common entities of non-Hodgkin's lymphoma. Genes Chromosomes Cancer 50(5):313-26, 2011. e-Pub 2011. PMID: 21305641.
- Ouyang J, Juszczynski P, Rodig SJ, Green MR, O'Donnell E, Currie T, Armant M, Takeyama K, Monti S, Rabinovich GA, Ritz J, Kutok JL, Shipp MA. Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders. Blood 117(16):4315-22, 2011. e-Pub 2011. PMID: 21300977.
- Green MR, Monti S, Dalla-Favera R, Pasqualucci L, Walsh NC, Schmidt-Supprian M, Kutok JL, Rodig SJ, Neuberg DS, Rajewsky K, Golub TR, Alt FW, Shipp MA, Manis JP. Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program. Proc Natl Acad Sci U S A 108(7):2873-8, 2011. e-Pub 2011. PMID: 21282644.
- Nguyen-Van D, Keane C, Han E, Jones K, Nourse JP, Vari F, Ross N, Crooks P, Ramuz O, Green M, Griffith L, Trappe R, Grigg A, Mollee P, Gandhi MK. Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly expresses EBNA3A with conserved CD8 T-cell epitopes. Am J Blood Res 1(2):146-59, 2011. e-Pub 2011. PMID: 22432076.
- Green MR, Monti S, Rodig SJ, Juszczynski P, Currie T, O'Donnell E, Chapuy B, Takeyama K, Neuberg D, Golub TR, Kutok JL, Shipp MA. Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. Blood 116(17):3268-77, 2010. e-Pub 2010. PMID: 20628145.
- Green MR, Jardine P, Wood P, Wellwood J, Lea RA, Marlton P, Griffiths LR. A new method to detect loss of heterozygosity using cohort heterozygosity comparisons. BMC Cancer 10:195, 2010. e-Pub 2010. PMID: 20462409.
- Green MR, Gandhi MK, Courtney MJ, Marlton P, Griffiths L. Relative abundance of full-length and truncated FOXP1 isoforms is associated with differential NFkappaB activity in Follicular Lymphoma. Leuk Res 33(12):1699-702, 2009. e-Pub 2009. PMID: 19487025.
- Green M, Gandhi MK, Camilleri E, Marlton P, Lea R, Griffiths L. High levels of BACH2 associated with lower levels of BCL2 transcript abundance in t(14;18)(q21;q34) translocation positive non-Hodgkin's lymphoma. Leuk Res 33(5):731-4, 2009. e-Pub 2008. PMID: 18929412.
- Yang H, Green MR. Harnessing lymphoma epigenetics to improve therapies. Blood. e-Pub 2020. PMID: 33206943.
Invited Articles
- Lunning M, Green M. Mutation of chromatin modifiers and organizers; an emerging hallmark of B-cell lymphoma. Blood Cancer J 5:e361, 2015.
- Green M, Vicente-Duenas C, Alizadeh A, Sanches Garcia I. Hit-and-run tumor stem cell reprogramming by the Bcl6 oncogene. Cell Cycle 13:1831-1832, 2014. PMID: 24867153.
- Green M, Alizadeh A. Common progenitor cells (CPCs) in mature B-cell malignancies: Implications for therapy. Curr Opin Hematol 21:333-340, 2014. PMID: 24811163.
- Green M. Chromatin modifying genes in follicular lymphoma. Blood 2017.
Editorials
- Green M. Considering Clonality in Precision Medicine. ASCO Post 6(11), 2015.
Abstracts
- García-Ramírez I, Shrishrimal S, González-Herrero I, Martín-Lorenzo A, Rodríguez-Hernández G, Duval R, Moore D, Ruiz-Roca L, Blanco O, Alonso-López D, De Las Rivas J, Klinkibiel D, Bast M, Greiner T, Vose J, Lunning M, Rodriguez-Lima F, Jiménez R, Criado F, Cenador M, Vicente-Dueñas C, Alizadeh A, Sánchez-García I, Green M. Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice. [Oral]. Annual Meeting of the Am Soc of Hematology, 2016.
- Hartert K, Tadros S, Moore D, Bouska A, Pak C, Heavican T, Liu C, Gentles A, Hartmann E, Kridel R, Smedby K, Juliusson G, Rosenquist R, Gascoyne R, Rosenwald A, Bast M, Vose J, Lunning M, Greiner T, Rodig S, Iqbal J, Levy R, Alizadeh A, Green M.. DNA Copy Number Gains of TCF4 (E2-2) are Associated with Poor Outcome in Diffuse Large B-cell Lymphoma. Annual Meeting of the American Society of Hematology, 2016.
- Khodadoust M, Olsson N, Wagar L, Chen B, Rawson K, Liu C, Steiner D, Rao S. Zhang L, Stehr H, Newman A, Czerwinski D, Carlton V, Moorhead M, Faham M, Kohrt H, Green M, Davis M, Levy R, Elias J, Alizadeh A. Antigen Presentation Profiling Reveals T-Cell Recognition of Lymphoma Immunoglobulin Neoantigens [Oral]. Annual Meeting of the American Society of Hematology, 2016.
- Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican T, Lachel C, Yu J, Fu K, Ferro R, Eldorghamy N, Greiner T, Vose J, Weisenburger D, Gascoyne R, Rosenwald A, Ott G, Campo E, Rimsza L, Jaffe E, Braziel R, Siebert R, Miles R, Dave S, Reddy A, McKeithan T, Staudt L, Green M, Chan W, Iqbal J. Comprehensive Genomic Analysis of Adult Burkitt Lymphoma Identifies the B-Cell Receptor Signaling Pathway as a Potential Therapeutic Target. Annual Meeting of the American Society of Hematology, 2016.
- Kurtz D, Scherer F, Green M, Khodadoust M, Klass D, Zhou L, Krishnan R, Glover C, Liu C, Kong K, Faham M, Levy R, Diehn M, Alizadeh A. Distinct early response dynamics of circulating tumor DNA and circulating tumor cells during therapy of B-cell NHL [Oral]. Annual Meeting of the American Society of Clinical Oncology, 2015.
- Scherer F, Kurtz D, Green M, Newman A, Klass D, Zhou L, Krishnan R, Liu C, Glover C, Ohgami R, Hicks R, Keane C, Kong K, Faham M, Hertzberg M, Gandhi M, Advani R, Levy R, Diehn M, Alizadeh A. Pre-treatment circulating tumor DNA as a biomarker for disease burden in diffuse large B cell lymphoma (DLBCL). Annual Meeting of the American Society of Clinical Oncology, 2015.
- Kurtz D*, Green M*, Bratman S, Liu C, Takahashi K, Glover C, Keane C, Kihira S, Kong K, Faham M, Karen C, Miklos D, Advani R, Levy R, Hertzberg M, Gandhi M, Diehn M, Alizadeh A. Noninvasive monitoring of cellular vs acellular tumor DNA from immunoglobulin genes for DLBCL. Annual Meeting of the American Society of Clinical Oncology [Oral], 2014.
- Keane C, Vari F, Hertzberg M, Green M, Han E, Seymour J, Hicks R, Gill D, Crooks P, Gould C, Jones K, Radford K, Griffiths L, Talaulikar D, Jain S, Tobin J, Gandhi M. Net antitumoral immunity and the predictive power of conventional prognosticators in diffuse large B-cell lymphoma. Annual Meeting of the American Society of Clinical Oncology, 2014.
- Green M, Brattman S, Liu C, Takahashi K, Glover C, Keane C, Kihira S, Kong K, Faham M, Corbelli K, Miklos D, Advani R, Levy R, Hertzberg M, Gandhi M, Diehn M, Alizadeh A. Utility of non-invasive monitoring of circulating tumor DNA at diagnosis, interim therapy, and relapse of DLBCL using high-throughput sequencing of immunoglobulin genes. Annual Meeting of the American Society of Hematology, 2013.
- Keane C, Vari F, Talaulikar D, Crooks P, Jones K, Han E, Gould C, Seymour J, Hertzberg M, Gill D, Green M, Jain S, Tobin J, Nicol W, Gandhi M. EBV positive DLBCL of the elderly is a heterogeneous disorder with outcome predicted by its immune microenvironment. International Congress on Malignant Lymphoma, 2013.
- Green M, Gentles A, Nair R, Irish J, Kihira S, Liu C, Kela I, Hoppmans E, Myklebust J, Ji H, Plevritis S, Levy R, Alizadeh A. The structure of stepwise clonal evolution events shaping Follicular lymphoma coding genomes [Oral]. International Congress on Malignant Lymphoma, 2013.
- Green M, Gentles A, Nair R, Irish J, Levy R, Alizadeh A. Hierarchy of somatic mutations arising during genomic evolution and progression of Follicular lymphoma [Oral]. Annual Meeting of the American Society of Hematology,, 2012.
Grant & Contract Support
Title: | Identifying/targeting mechanisms of lymphomagenesis driven by CREBBP inactivation |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Genetic features of Reed-Sternberg cells and their interplay with tumor-infiltrating macrophages in classical Hodgkin's lymphoma |
Funding Source: | Polish National Science Center |
Role: | Co-Investigator |
Title: | Integrating immunity and genetics in Follicular Lymphoma to establish a prognostic score fit for the modern era |
Funding Source: | National Health and Medical Research Council, Australia |
Role: | Co-Investigator |
Title: | Concurrent TET2 and IDH2 mutations in the pathogenesis of angioimmunoblastic T-cell lymphoma |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Predicting Response and Improving Efficacy of CAR T-cell Therapy in DLBCL |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Principal Investigator |
Title: | Functional characterization and rational therapeutic targeting of 18q DNA copy number gains in diffuse large B-cell lymphoma |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |