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Neal G. Copeland, Ph.D.

Department of Genetics, Division of Discovery Science

About Dr. Neal G. Copeland

Neal Copeland received his Ph.D. in Biochemistry from the University of Utah. Following postdoctoral studies at Harvard Medical School, he joined the staff of The Jackson Laboratory and then the National Cancer Institute-Frederick, where he was Director of the Mammalian Genetics Laboratory, the forerunner of the Mouse Cancer Genetics Program that he also directed. He moved to the Institute of Molecular and Cell Biology in Singapore in 2006, where he served as the Executive Director for most of his stay. In 2011 he returned to the U.S. to serve as Director of the Cancer Biology Program at Houston Methodist Research Institute. For more than 35 years he co-headed a laboratory with Nancy Jenkins, successfully modeling many different types of human disease in the mouse but focusing exclusively on cancer the last 11 years. They have co-authored more than 800 papers and are among the most cited biomedical research scientists in the world today. Copeland has served on numerous scientific advisory and editorial boards and has consulted for several biotechnology and pharmaceutical companies. Dr. Copeland is also a member of the US National Academy of Sciences. In 2017, Jenkins and Copeland closed their lab and moved to the Department of Genetics at the MD Anderson Cancer Center.

AREAS OF EXPERTISE
Mouse models of cancer/ Insertional mutagenesis/ Forward genetic screens/ High throughput sequencing/ Candidate cancer gene detection

Read about Dr. Copeland in Cancerwise

Primary Appointment

Professor of Practice, Department of Genetics, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX

Emeritus Professor of Oncology, Houston Methodist Research Institute, Houston, Texas

Education & Training

Degree-Granting Education

1976	The University of Utah, Salt Lake City, Utah, US, Biochemistry, Ph.D
1971	The University of Utah, Salt Lake City, Utah, US, Biology, B.S

Postgraduate Training

1976-1980

Postdoctoral Fellow, Viral Oncology, Harvard Medical School, Boston, Massachusetts

Honors & Awards

2022 - Present	American Association for Cancer Research (AACR) Academy
2020	Prince Hitachi Prize for Comparative Oncology
2011 - Present	Academy of Medicine, Engineering and Science of Texas
2009 - Present	National Academy of Sciences

Selected Publications

Peer-Reviewed Articles

Hardwick J, Rodriguez-Hernaez J, Gambi G, Venters BJ, Guo Y, Li L, Love PE, Copeland NG, Jenkins NA, Papaioannou D, Aifantis I, Tsirigos A, Ivan M, Dave UP. The common murine retroviral integration site activating Hhex marks a distal regulatory enhancer co-opted in human early T-cell precursor leukemia. J Biol Chem 301(3):108233, 2025. e-Pub 2025. PMID: 39880094.
Iida N, Muranaka Y, Park JW, Sekine S, Copeland NG, Jenkins NA, Shiraishi Y, Oshima M, Takeda H. Sleeping Beauty transposon mutagenesis in mouse intestinal organoids identifies genes involved in tumor progression and metastasis. Cancer Gene Ther 31(4):527-536, 2024. e-Pub 2024. PMID: 38177308.
Vu HN, Valdimarsson MM, Sigurbjörnsdóttir S, Bergsteinsdóttir K, Debbache J, Bismuth K, Swing DA, Hallsson JH, Larue L, Arnheiter H, Copeland NG, Jenkins NA, Heidarsson PO, Steingrímsson E. Novel mechanisms of MITF regulation identified in a mouse suppressor screen. EMBO Rep. e-Pub 2023. PMID: 39169200.
Vu HN, Valdimarsson MM, Sigurbjörnsdóttir S, Bergsteinsdóttir K, Debbache J, Bismuth K, Swing DA, Hallsson JH, Larue L, Arnheiter H, Copeland NG, Jenkins NA, Heidarsson PO, Steingrímsson E. Novel mechanisms of MITF regulation and melanoma predisposition identified in a mouse suppressor screen. bioRxiv, 2023. e-Pub 2023. PMID: 37786677.
Shiode Y, Kodama T, Shigeno S, Murai K, Tanaka S, Newberg JY, Kondo J, Kobayashi S, Yamada R, Hikita H, Sakamori R, Suemizu H, Tatsumi T, Eguchi H, Jenkins NA, Copeland NG, Takehara T. TNF receptor-related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF-κB-inducing kinase-mediated hepatocyte transdifferentiation. Hepatology, 2023. e-Pub 2023. PMID: 34995376.
Kodama T, Kodama M, Jenkins NA, Copeland NG, Chen HJ, Wei Z. Ring Finger Protein 125 Is an Anti-Proliferative Tumor Suppressor in Hepatocellular Carcinoma. Cancers (Basel) 14(11), 2022. e-Pub 2022. PMID: 35681566.
Kodama M, Shimura H, Tien JC, Newberg JY, Kodama T, Wei Z, Rangel R, Yoshihara K, Kuruma A, Nakae A, Hashimoto K, Sawada K, Kimura T, Jenkins NA, Copeland NG. Sleeping Beauty transposon mutagenesis identifies genes driving the initiation and metastasis of uterine leiomyosarcoma. Cancer Res 81(21):5413-5424, 2021. e-Pub 2021. PMID: 34475109.
Aiderus A, Newberg JY, Guzman-Rojas L, Contreras-Sandoval AM, Meshey AL, Jones DJ, Amaya-Manzanares F, Rangel R, Ward JM, Lee SC, Ban KH, Rogers K, Rogers SM, Selvanesan L, McNoe LA, Copeland NG, Jenkins NA, Tsai KY, Black MA, Mann KM, Mann MB. Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression. PLoS Genet 17(8):e1009094, 2021. e-Pub 2021. PMID: 34398873.
Nakae A, Kodama M, Okamoto T, Tokunaga M, Shimura H, Hashimoto K, Sawada K, Kodama T, Copeland NG, Jenkins NA, Kimura T. Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1. Biochem Biophys Res Commun 552:120-127, 2021. e-Pub 2021. PMID: 33744759.
Aiderus A, Contreras-Sandoval AM, Meshey AL, Newberg JY, Ward JM, Swing DA, Copeland NG, Jenkins NA, Mann KM, Mann MB. Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation. Cancers (Basel) 13(2), 2021. e-Pub 2021. PMID: 33435458.
Gudmundsson KO, Nguyen N, Oakley K, Han Y, Gudmundsdottir B, Liu P, Tessarollo L, Jenkins NA, Copeland NG, Du Y. Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence. Proc Natl Acad Sci U S A 117(50):31945-31953, 2020. e-Pub 2020. PMID: 33268499.
Kodama T, Marian TA, Lee H, Kodama M, Li J, Parmacek MS, Jenkins NA, Copeland NG, Wei Z. MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM. Proc Natl Acad Sci U S A 116(47):23625-23635, 2019. e-Pub 2019. PMID: 31690663.
Takeda H, Kataoka S, Nakayama M, Ali MAE, Oshima H, Yamamoto D, Park JW, Takegami Y, An T, Jenkins NA, Copeland NG, Oshima M. CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes. Proc Natl Acad Sci U S A 116(31):15635-15644, 2019. e-Pub 2019. PMID: 31300537.
Kodama T, Yi J, Newberg JY, Tien JC, Wu H, Finegold MJ, Kodama M, Wei Z, Tamura T, Takehara T, Johnson RL, Jenkins NA, Copeland NG. Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis. Proc Natl Acad Sci U S A 115(44):E10417-E10426, 2018. e-Pub 2018. PMID: 30327349.
Newberg JY, Black MA, Jenkins NA, Copeland NG, Mann KM, Mann MB. SB Driver Analysis: a Sleeping Beauty cancer driver analysis framework for identifying and prioritizing experimentally actionable oncogenes and tumor suppressors. Nucleic Acids Res 46(16):e94, 2018. e-Pub 2018. PMID: 29846651.
Alexander CJ, Wagner W, Copeland NG, Jenkins NA, Hammer JA. Creation of a myosin Va-TAP-tagged mouse and identification of potential myosin Va-interacting proteins in the cerebellum. Cytoskeleton (Hoboken) 75(9):395-409, 2018. e-Pub 2018. PMID: 29979496.
De Bruyckere E, Simon R, Nestel S, Heimrich B, Katzel D, Egorov AV, Liu P, Jenkins NA, Copeland NG, Schwegler H, Draguhn A, Britsch S. Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2. Front Mol Neurosci 11:103, 2018. e-Pub 2018. PMID: 29674952.
Newberg JY, Mann KM, Mann MB, Jenkins NA, Copeland NG. SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers. Nucleic Acids Res 46(D1):D1011-D1017, 2018. e-Pub 2018. PMID: 29059366.
Short SP, Kondo J, Smalley-Freed WG, Takeda H, Dohn MR, Powell AE, Carnahan RH, Washington MK, Tripathi M, Payne DM, Jenkins NA, Copeland NG, Coffey RJ, Reynolds AB. p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia. J Clin Invest 127(12):4462-4476, 2017. e-Pub 2017. PMID: 29130932.
Kodama M, Kodama T, Newberg JY, Katayama H, Kobayashi M, Hanash SM, Yoshihara K, Wei Z, Tien JC, Rangel R, Hashimoto K, Mabuchi S, Sawada K, Kimura T, Copeland NG, Jenkins NA. In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer. Proc Natl Acad Sci U S A 114(35):E7301-E7310, 2017. e-Pub 2017. PMID: 28811376.
Rangel R, Guzman-Rojas L, Kodama T, Kodama M, Newberg JY, Copeland NG, Jenkins NA. Identification of New Tumor Suppressor Genes in Triple-Negative Breast Cancer. Cancer Res 77(15):4089-4101, 2017. e-Pub 2017. PMID: 28724549.
Chen L, Jenjaroenpun P, Pillai AM, Ivshina AV, Ow GS, Efthimios M, Zhiqun T, Tan TZ, Lee SC, Rogers K, Ward JM, Mori S, Adams DJ, Jenkins NA, Copeland NG, Ban KH, Kuznetsov VA, Thiery JP. Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. Proc Natl Acad Sci U S A 114(11):E2215-E2224, 2017. e-Pub 2017. PMID: 28251929.
Rangel R, Lee SC, Hon-Kim Ban K, Guzman-Rojas L, Mann MB, Newberg JY, Kodama T, McNoe LA, Selvanesan L, Ward JM, Rust AG, Chin KY, Black MA, Jenkins NA, Copeland NG. Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression. Proc Natl Acad Sci U S A 113(48):E7749-E7758, 2016. e-Pub 2016. PMID: 27849608.
Mann KM, Newberg JY, Black MA, Jones DJ, Amaya-Manzanares F, Guzman-Rojas L, Kodama T, Ward JM, Rust AG, van der Weyden L, Yew CC, Waters JL, Leung ML, Rogers K, Rogers SM, McNoe LA, Selvanesan L, Navin N, Jenkins NA, Copeland NG, Mann MB. Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. Nat Biotechnol 34(9):962-72, 2016. e-Pub 2016. PMID: 27479497.
Chen HJ, Wei Z, Sun J, Bhattacharya A, Savage DJ, Serda R, Mackeyev Y, Curley SA, Bu P, Wang L, Chen S, Cohen-Gould L, Huang E, Shen X, Lipkin SM, Copeland NG, Jenkins NA, Shuler ML. A recellularized human colon model identifies cancer driver genes. Nat Biotechnol 34(8):845-51, 2016. e-Pub 2016. PMID: 27398792.
Kodama T, Bard-Chapeau EA, Newberg JY, Kodama M, Rangel R, Yoshihara K, Ward JM, Jenkins NA, Copeland NG. Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma. Gastroenterology 151(2):324-337.e12, 2016. e-Pub 2016. PMID: 27178121.
Kodama T, Newberg JY, Kodama M, Rangel R, Yoshihara K, Tien JC, Parsons PH, Wu H, Finegold MJ, Copeland NG, Jenkins NA. Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma. Proc Natl Acad Sci U S A 113(24):E3384-93, 2016. e-Pub 2016. PMID: 27247392.
Sayadi A, Jeyakani J, Seet SH, Wei CL, Bourque G, Bard FA, Jenkins NA, Copeland NG, Bard-Chapeau EA. Functional features of EVI1 and EVI1Delta324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity. Oncogene 35(18):2311-21, 2016. e-Pub 2016. PMID: 26234679.
Takeda H, Rust AG, Ward JM, Yew CC, Jenkins NA, Copeland NG. Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. Proc Natl Acad Sci U S A 113(14):E2057-65, 2016. e-Pub 2016. PMID: 27006499.
Simon R, Baumann L, Fischer J, Seigfried FA, De Bruyckere E, Liu P, Jenkins NA, Copeland NG, Schwegler H, Britsch S. Structure-function integrity of the adult hippocampus depends on the transcription factor Bcl11b/Ctip2. Genes Brain Behav 15(4):405-19, 2016. e-Pub 2016. PMID: 26915960.
Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F. Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife 5, 2016. e-Pub 2016. PMID: 26857994.
Basheer WA, Harris BS, Mentrup HL, Abreha M, Thames EL, Lea JB, Swing DA, Copeland NG, Jenkins NA, Price RL, Matesic LE. Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis. J Mol Cell Cardiol 88:1-13, 2015. e-Pub 2015. PMID: 26386426.
Wiegreffe C, Simon R, Peschkes K, Kling C, Strehle M, Cheng J, Srivatsa S, Liu P, Jenkins NA, Copeland NG, Tarabykin V, Britsch S. Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Neuron 87(2):311-25, 2015. e-Pub 2015. PMID: 26182416.
Yu Y, Wang C, Clare S, Wang J, Lee SC, Brandt C, Burke S, Lu L, He D, Jenkins NA, Copeland NG, Dougan G, Liu P. The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development. J Exp Med 212(6):865-74, 2015. e-Pub 2015. PMID: 25964371.
Mann MB, Black MA, Jones DJ, Ward JM, Yew CC, Newberg JY, Dupuy AJ, Rust AG, Bosenberg MW, McMahon M, Print CG, Copeland NG, Jenkins NA. Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma. Nat Genet 47(5):486-95, 2015. e-Pub 2015. PMID: 25848750.
Takeda H, Wei Z, Koso H, Rust AG, Yew CC, Mann MB, Ward JM, Adams DJ, Copeland NG, Jenkins NA. Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression. Nat Genet 47(2):142-50, 2015. e-Pub 2015. PMID: 25559195.
Khaled WT, Choon Lee S, Stingl J, Chen X, Raza Ali H, Rueda OM, Hadi F, Wang J, Yu Y, Chin SF, Stratton M, Futreal A, Jenkins NA, Aparicio S, Copeland NG, Watson CJ, Caldas C, Liu P. BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells. Nat Commun 6:5987, 2015. e-Pub 2015. PMID: 25574598.
Wiles WG 4th, Mou Z, Du Y, Long AB, Scharer CD, Bilir B, Spyropoulos DD, Jenkins NA, Copeland NG, Martin WD, Moreno CS. Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality. In Vivo 28(5):709-18, 2014. e-Pub 2014. PMID: 25189881.
Koso H, Tsuhako A, Lyons E, Ward JM, Rust AG, Adams DJ, Jenkins NA, Copeland NG, Watanabe S. Identification of FoxR2 as an oncogene in medulloblastoma. Cancer Res 74(8):2351-61, 2014. e-Pub 2014. PMID: 24599127.
Mann KM, Jenkins NA, Copeland NG, Mann MB. Transposon insertional mutagenesis models of cancer. Cold Spring Harb Protoc 2014(3):235-47, 2014. e-Pub 2014. PMID: 24591685.
Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG. Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects. PLoS One 9(2):e89397, 2014. e-Pub 2014. PMID: 24586749.
Smith S, Tripathi R, Goodings C, Cleveland S, Mathias E, Hardaway JA, Elliott N, Yi Y, Chen X, Downing J, Mullighan C, Swing DA, Tessarollo L, Li L, Love P, Jenkins NA, Copeland NG, Thompson MA, Du Y, Dave UP. LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways. PLoS One 9(1):e85883, 2014. e-Pub 2014. PMID: 24465765.
Bard-Chapeau EA, Nguyen AT, Rust AG, Sayadi A, Lee P, Chua BQ, New LS, de Jong J, Ward JM, Chin CK, Chew V, Toh HC, Abastado JP, Benoukraf T, Soong R, Bard FA, Dupuy AJ, Johnson RL, Radda GK, Chan EC, Wessels LF, Adams DJ, Jenkins NA, Copeland NG. Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model. Nat Genet 46(1):24-32, 2014. e-Pub 2014. PMID: 24316982.
Yamben IF, Rachel RA, Shatadal S, Copeland NG, Jenkins NA, Warming S, Griep AE. Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse. Dev Biol 384(1):41-52, 2013. e-Pub 2013. PMID: 24095903.
Genovesi LA, Ng CG, Davis MJ, Remke M, Taylor MD, Adams DJ, Rust AG, Ward JM, Ban KH, Jenkins NA, Copeland NG, Wainwright BJ. Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups. Proc Natl Acad Sci U S A 110(46):E4325-34, 2013. e-Pub 2013. PMID: 24167280.
Bard-Chapeau EA, Gunaratne J, Kumar P, Chua BQ, Muller J, Bard FA, Blackstock W, Copeland NG, Jenkins NA. EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation. Proc Natl Acad Sci U S A 110(31):E2885-94, 2013. e-Pub 2013. PMID: 23858473.
Kiviranta R, Yamana K, Saito H, Ho DK, Laine J, Tarkkonen K, Nieminen-Pihala V, Hesse E, Correa D, Maatta J, Tessarollo L, Rosen ED, Horne WC, Jenkins NA, Copeland NG, Warming S, Baron R. Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages. J Exp Med 210(5):969-85, 2013. e-Pub 2013. PMID: 23569325.
Tang JZ, Carmichael CL, Shi W, Metcalf D, Ng AP, Hyland CD, Jenkins NA, Copeland NG, Howell VM, Zhao ZJ, Smyth GK, Kile BT, Alexander WS. Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia. Proc Natl Acad Sci U S A 110(15):6091-6, 2013. e-Pub 2013. PMID: 23533276.
Riordan JD, Keng VW, Tschida BR, Scheetz TE, Bell JB, Podetz-Pedersen KM, Moser CD, Copeland NG, Jenkins NA, Roberts LR, Largaespada DA, Dupuy AJ. Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis. PLoS Genet 9(4):e1003441, 2013. e-Pub 2013. PMID: 23593033.
Takeda H, Koso H, Tessarollo L, Copeland NG, Jenkins NA. Musashi1-CreER(T2) : a new cre line for conditional mutagenesis in neural stem cells. Genesis 51(2):128-34, 2013. e-Pub 2013. PMID: 23132814.
Yu Y, Wang J, Khaled W, Burke S, Li P, Chen X, Yang W, Jenkins NA, Copeland NG, Zhang S, Liu P. Bcl11a is essential for lymphoid development and negatively regulates p53. J Exp Med 209(13):2467-83, 2012. e-Pub 2012. PMID: 23230003.
Unnisa Z, Clark JP, Roychoudhury J, Thomas E, Tessarollo L, Copeland NG, Jenkins NA, Grimes HL, Kumar AR. Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress. Blood 120(25):4973-81, 2012. e-Pub 2012. PMID: 23091297.
Kocabas F, Zheng J, Thet S, Copeland NG, Jenkins NA, DeBerardinis RJ, Zhang C, Sadek HA. Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells. Blood 120(25):4963-72, 2012. e-Pub 2012. PMID: 22995899.
Chew V, Tow C, Huang C, Bard-Chapeau E, Copeland NG, Jenkins NA, Weber A, Lim KH, Toh HC, Heikenwalder M, Ng IO, Nardin A, Abastado JP. Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients. J Natl Cancer Inst 104(23):1796-807, 2012. e-Pub 2012. PMID: 23197495.
Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Pillars article: lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. 1992. J Immunol 189(11):5101-4, 2012. e-Pub 2012. PMID: 23169862.
Biankin AV, Waddell N, Kassahn KS, Gingras MC, Muthuswamy LB, Johns AL, Miller DK, Wilson PJ, Patch AM, Wu J, Chang DK, Cowley MJ, Gardiner BB, Song S, Harliwong I, Idrisoglu S, Nourse C, Nourbakhsh E, Manning S, Wani S, Gongora M, Pajic M, Scarlett CJ, Gill AJ, Pinho AV, Rooman I, Anderson M, Holmes O, Leonard C, Taylor D, Wood S, Xu Q, Nones K, Fink JL, Christ A, Bruxner T, Cloonan N, Kolle G, Newell F, Pinese M, Mead RS, Humphris JL, Kaplan W, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chou A, Chin VT, Chantrill LA, Mawson A, Samra JS, Kench JG, Lovell JA, Daly RJ, Merrett ND, Toon C, Epari K, Nguyen NQ, Barbour A, Zeps N, Kakkar N, Zhao F, Wu YQ, Wang M, Muzny DM, Fisher WE, Brunicardi FC, Hodges SE, Reid JG, Drummond J, Chang K, Han Y, Lewis LR, Dinh H, Buhay CJ, Beck T, Timms L, Sam M, Begley K, Brown A, Pai D, Panchal A, Buchner N, De Borja R, Denroche RE, Yung CK, Serra S, Onetto N, Mukhopadhyay D, Tsao MS, Shaw PA, Petersen GM, Gallinger S, Hruban RH, Maitra A, Iacobuzio-Donahue CA, Schulick RD, Wolfgang CL, Morgan RA, Lawlor RT, Capelli P, Corbo V, Scardoni M, Tortora G, Tempero MA, Mann KM, Jenkins NA, Perez-Mancera PA, Adams DJ, Largaespada DA, Wessels LF, Rust AG, Stein LD, Tuveson DA, Copeland NG, Musgrove EA, Scarpa A, Eshleman JR, Hudson TJ, Sutherland RL, Wheeler DA, Pearson JV, McPherson JD, Gibbs RA, Grimmond SM. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 491(7424):399-405, 2012. e-Pub 2012. PMID: 23103869.
Koso H, Takeda H, Yew CC, Ward JM, Nariai N, Ueno K, Nagasaki M, Watanabe S, Rust AG, Adams DJ, Copeland NG, Jenkins NA. Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells. Proc Natl Acad Sci U S A 109(44):E2998-3007, 2012. e-Pub 2012. PMID: 23045694.
Wu XS, Masedunskas A, Weigert R, Copeland NG, Jenkins NA, Hammer JA. Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes. Proc Natl Acad Sci U S A 109(31):E2101-9, 2012. e-Pub 2012. PMID: 22753477.
Simon R, Brylka H, Schwegler H, Venkataramanappa S, Andratschke J, Wiegreffe C, Liu P, Fuchs E, Jenkins NA, Copeland NG, Birchmeier C, Britsch S. A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis. EMBO J 31(13):2922-36, 2012. e-Pub 2012. PMID: 22588081.
Oakley K, Han Y, Vishwakarma BA, Chu S, Bhatia R, Gudmundsson KO, Keller J, Chen X, Vasko V, Jenkins NA, Copeland NG, Du Y. Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10. Blood 119(25):6099-108, 2012. e-Pub 2012. PMID: 22566606.
John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S. Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development 139(10):1831-41, 2012. e-Pub 2012. PMID: 22491945.
Mann KM, Ward JM, Yew CC, Kovochich A, Dawson DW, Black MA, Brett BT, Sheetz TE, Dupuy AJ, Chang DK, Biankin AV, Waddell N, Kassahn KS, Grimmond SM, Rust AG, Adams DJ, Jenkins NA, Copeland NG. Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Proc Natl Acad Sci U S A 109(16):5934-41, 2012. e-Pub 2012. PMID: 22421440.
Bard-Chapeau EA, Jeyakani J, Kok CH, Muller J, Chua BQ, Gunaratne J, Batagov A, Jenjaroenpun P, Kuznetsov VA, Wei CL, D'Andrea RJ, Bourque G, Jenkins NA, Copeland NG. Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors. Proc Natl Acad Sci U S A 109(6):2168-73, 2012. e-Pub 2012. PMID: 22308434.
Aue G, Du Y, Cleveland SM, Smith SB, Dave UP, Liu D, Weniger MA, Metais JY, Jenkins NA, Copeland NG, Dunbar CE. Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia. Blood 118(17):4674-81, 2011. e-Pub 2011. PMID: 21878674.
Berquam-Vrieze KE, Nannapaneni K, Brett BT, Holmfeldt L, Ma J, Zagorodna O, Jenkins NA, Copeland NG, Meyerholz DK, Knudson CM, Mullighan CG, Scheetz TE, Dupuy AJ. Cell of origin strongly influences genetic selection in a mouse model of T-ALL. Blood 118(17):4646-56, 2011. e-Pub 2011. PMID: 21828136.
Vanvalkenburgh J, Albu DI, Bapanpally C, Casanova S, Califano D, Jones DM, Ignatowicz L, Kawamoto S, Fagarasan S, Jenkins NA, Copeland NG, Liu P, Avram D. Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease. J Exp Med 208(10):2069-81, 2011. e-Pub 2011. PMID: 21875956.
Albu DI, VanValkenburgh J, Morin N, Califano D, Jenkins NA, Copeland NG, Liu P, Avram D. Transcription factor Bcl11b controls selection of invariant natural killer T-cells by regulating glycolipid presentation in double-positive thymocytes. Proc Natl Acad Sci U S A 108(15):6211-6, 2011. e-Pub 2011. PMID: 21444811.
Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, Jenkins NA, Copeland NG, Galter D, Thomas B, Lee MK, Dawson TM, Dawson VL, Moore DJ. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. PLoS One 6(4):e18568, 2011. e-Pub 2011. PMID: 21494637.
Cui J, Wang Z, Cheng Q, Lin R, Zhang XM, Leung PS, Copeland NG, Jenkins NA, Yao KM, Huang JD. Targeted inactivation of kinesin-1 in pancreatic beta-cells in vivo leads to insulin secretory deficiency. Diabetes 60(1):320-30, 2011. e-Pub 2011. PMID: 20870970.
Correa D, Hesse E, Seriwatanachai D, Kiviranta R, Saito H, Yamana K, Neff L, Atfi A, Coillard L, Sitara D, Maeda Y, Warming S, Jenkins NA, Copeland NG, Horne WC, Lanske B, Baron R. Zfp521 is a target gene and key effector of parathyroid hormone-related peptide signaling in growth plate chondrocytes. Dev Cell 19(4):533-46, 2010. e-Pub 2010. PMID: 20951345.
Fernandez-Diaz LC, Laurent A, Girasoli S, Turco M, Longobardi E, Iotti G, Jenkins NA, Fiorenza MT, Copeland NG, Blasi F. The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells. Development 137(20):3393-403, 2010. e-Pub 2010. PMID: 20826531.
Zhang S, Rozell M, Verma RK, Albu DI, Califano D, VanValkenburgh J, Merchant A, Rangel-Moreno J, Randall TD, Jenkins NA, Copeland NG, Liu P, Avram D. Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b. J Exp Med 207(8):1687-99, 2010. e-Pub 2010. PMID: 20660613.
Li P, Burke S, Wang J, Chen X, Ortiz M, Lee SC, Lu D, Campos L, Goulding D, Ng BL, Dougan G, Huntly B, Gottgens B, Jenkins NA, Copeland NG, Colucci F, Liu P. Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion. Science 329(5987):85-9, 2010. e-Pub 2010. PMID: 20538915.
Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA. Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model. Hum Mol Genet 19(11):2087-98, 2010. e-Pub 2010. PMID: 20185556.
Mendrysa SM, Akagi K, Roayaei J, Lien WH, Copeland NG, Jenkins NA, Eisenman RN. An Integrated Genetic-Genomic Approach for the Identification of Novel Cancer Loci in Mice Sensitized to c-Myc-Induced Apoptosis. Genes Cancer 1(5):465-479, 2010. e-Pub 2010. PMID: 20927200.
Wong ES, Ban KH, Mutalif R, Jenkins NA, Copeland NG, Stewart CL. A simple procedure for the efficient derivation of mouse ES cells. Methods Enzymol 476:265-83, 2010. e-Pub 2010. PMID: 20691871.
Mazzucchelli RI, Warming S, Lawrence SM, Ishii M, Abshari M, Washington AV, Feigenbaum L, Warner AC, Sims DJ, Li WQ, Hixon JA, Gray DH, Rich BE, Morrow M, Anver MR, Cherry J, Naf D, Sternberg LR, McVicar DW, Farr AG, Germain RN, Rogers K, Jenkins NA, Copeland NG, Durum SK. Visualization and identification of IL-7 producing cells in reporter mice. PLoS One 4(11):e7637, 2009. e-Pub 2009. PMID: 19907640.
Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, Weiss WA, Jenkins RB, Largaespada DA. Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality. Cancer Res 69(21):8429-37, 2009. e-Pub 2009. PMID: 19843846.
Bosticardo M, Ghosh A, Du Y, Jenkins NA, Copeland NG, Candotti F. Self-inactivating retroviral vector-mediated gene transfer induces oncogene activation and immortalization of primary murine bone marrow cells. Mol Ther 17(11):1910-8, 2009. e-Pub 2009. PMID: 19638958.
Dupuy AJ, Rogers LM, Kim J, Nannapaneni K, Starr TK, Liu P, Largaespada DA, Scheetz TE, Jenkins NA, Copeland NG. A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice. Cancer Res 69(20):8150-6, 2009. e-Pub 2009. PMID: 19808965.
Bauer GL, Praetorius C, Bergsteinsdottir K, Hallsson JH, Gisladottir BK, Schepsky A, Swing DA, O'Sullivan TN, Arnheiter H, Bismuth K, Debbache J, Fletcher C, Warming S, Copeland NG, Jenkins NA, Steingrimsson E. The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by bacterial artificial chromosome transgene rescue. Genetics 183(2):581-94, 2009. e-Pub 2009. PMID: 19635938.
Uranishi H, Zolotukhin AS, Lindtner S, Warming S, Zhang GM, Bear J, Copeland NG, Jenkins NA, Pavlakis GN, Felber BK. The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1. J Biol Chem 284(38):26106-16, 2009. e-Pub 2009. PMID: 19586903.
Lauchle JO, Kim D, Le DT, Akagi K, Crone M, Krisman K, Warner K, Bonifas JM, Li Q, Coakley KM, Diaz-Flores E, Gorman M, Przybranowski S, Tran M, Kogan SC, Roose JP, Copeland NG, Jenkins NA, Parada L, Wolff L, Sebolt-Leopold J, Shannon K. Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature 461(7262):411-4, 2009. e-Pub 2009. PMID: 19727076.
Miyazaki K, Yamasaki N, Oda H, Kuwata T, Kanno Y, Miyazaki M, Komeno Y, Kitaura J, Honda Z, Warming S, Jenkins NA, Copeland NG, Kitamura T, Nakamura T, Honda H. Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia. Blood 113(19):4702-10, 2009. e-Pub 2009. PMID: 19234145.
Dave UP, Akagi K, Tripathi R, Cleveland SM, Thompson MA, Yi M, Stephens R, Downing JR, Jenkins NA, Copeland NG. Murine leukemias with retroviral insertions at Lmo2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy. PLoS Genet 5(5):e1000491, 2009. e-Pub 2009. PMID: 19461887.
Starr TK, Allaei R, Silverstein KA, Staggs RA, Sarver AL, Bergemann TL, Gupta M, O'Sullivan MG, Matise I, Dupuy AJ, Collier LS, Powers S, Oberg AL, Asmann YW, Thibodeau SN, Tessarollo L, Copeland NG, Jenkins NA, Cormier RT, Largaespada DA. A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. Science 323(5922):1747-50, 2009. e-Pub 2009. PMID: 19251594.
Keng VW, Villanueva A, Chiang DY, Dupuy AJ, Ryan BJ, Matise I, Silverstein KA, Sarver A, Starr TK, Akagi K, Tessarollo L, Collier LS, Powers S, Lowe SW, Jenkins NA, Copeland NG, Llovet JM, Largaespada DA. A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nat Biotechnol 27(3):264-74, 2009. e-Pub 2009. PMID: 19234449.
Su Q, Prosser HM, Campos LS, Ortiz M, Nakamura T, Warren M, Dupuy AJ, Jenkins NA, Copeland NG, Bradley A, Liu P. A DNA transposon-based approach to validate oncogenic mutations in the mouse. Proc Natl Acad Sci U S A 105(50):19904-9, 2008. e-Pub 2008. PMID: 19064922.
Stankunas K, Shang C, Twu KY, Kao SC, Jenkins NA, Copeland NG, Sanyal M, Selleri L, Cleary ML, Chang CP. Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease. Circ Res 103(7):702-9, 2008. e-Pub 2008. PMID: 18723445.
Chen Z, Montcouquiol M, Calderon R, Jenkins NA, Copeland NG, Kelley MW, Noben-Trauth K. Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti. J Neurosci 28(26):6633-41, 2008. e-Pub 2008. PMID: 18579736.
Shembade N, Harhaj NS, Parvatiyar K, Copeland NG, Jenkins NA, Matesic LE, Harhaj EW. The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nat Immunol 9(3):254-62, 2008. e-Pub 2008. PMID: 18246070.
Jiang X, Tian F, Du Y, Copeland NG, Jenkins NA, Tessarollo L, Wu X, Pan H, Hu XZ, Xu K, Kenney H, Egan SE, Turley H, Harris AL, Marini AM, Lipsky RH. BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. J Neurosci 28(5):1118-30, 2008. e-Pub 2008. PMID: 18234890.
Albu DI, Feng D, Bhattacharya D, Jenkins NA, Copeland NG, Liu P, Avram D. BCL11B is required for positive selection and survival of double-positive thymocytes. J Exp Med 204(12):3003-15, 2007. e-Pub 2007. PMID: 17998389.
Colomer Gould VF, Goti D, Pearce D, Gonzalez GA, Gao H, Bermudez de Leon M, Jenkins NA, Copeland NG, Ross CA, Brown DR. A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice. Neurobiol Dis 27(3):362-9, 2007. e-Pub 2007. PMID: 17632007.
Boesze-Battaglia K, Song H, Sokolov M, Lillo C, Pankoski-Walker L, Gretzula C, Gallagher B, Rachel RA, Jenkins NA, Copeland NG, Morris F, Jacob J, Yeagle P, Williams DS, Damek-Poprawa M. The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator. Biochemistry 46(5):1256-72, 2007. e-Pub 2007. PMID: 17260955.
Matesic LE, Haines DC, Copeland NG, Jenkins NA. Itch genetically interacts with Notch1 in a mouse autoimmune disease model. Hum Mol Genet 15(24):3485-97, 2006. e-Pub 2006. PMID: 17095521.
Warming S, Rachel RA, Jenkins NA, Copeland NG. Zfp423 is required for normal cerebellar development. Mol Cell Biol 26(18):6913-22, 2006. e-Pub 2006. PMID: 16943432.
Suzuki T, Minehata K, Akagi K, Jenkins NA, Copeland NG. Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice. EMBO J 25(14):3422-31, 2006. e-Pub 2006. PMID: 16858412.
Boillee S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312(5778):1389-92, 2006. e-Pub 2006. PMID: 16741123.
Montcouquiol M, Sans N, Huss D, Kach J, Dickman JD, Forge A, Rachel RA, Copeland NG, Jenkins NA, Bogani D, Murdoch J, Warchol ME, Wenthold RJ, Kelley MW. Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals. J Neurosci 26(19):5265-75, 2006. e-Pub 2006. PMID: 16687519.
Ott MG, Schmidt M, Schwarzwaelder K, Stein S, Siler U, Koehl U, Glimm H, Kuhlcke K, Schilz A, Kunkel H, Naundorf S, Brinkmann A, Deichmann A, Fischer M, Ball C, Pilz I, Dunbar C, Du Y, Jenkins NA, Copeland NG, Luthi U, Hassan M, Thrasher AJ, Hoelzer D, von Kalle C, Seger R, Grez M. Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat Med 12(4):401-9, 2006. e-Pub 2006. PMID: 16582916.
Tanaka Y, Igarashi S, Nakamura M, Gafni J, Torcassi C, Schilling G, Crippen D, Wood JD, Sawa A, Jenkins NA, Copeland NG, Borchelt DR, Ross CA, Ellerby LM. Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin. Neurobiol Dis 21(2):381-91, 2006. e-Pub 2006. PMID: 16150600.
Boyd KE, Xiao YY, Fan K, Poholek A, Copeland NG, Jenkins NA, Perkins AS. Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors via transactivation of proviral LTR. Blood 107(2):733-41, 2006. e-Pub 2006. PMID: 16204320.
Martin LJ, Pan Y, Price AC, Sterling W, Copeland NG, Jenkins NA, Price DL, Lee MK. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J Neurosci 26(1):41-50, 2006. e-Pub 2006. PMID: 16399671.
Du Y, Jenkins NA, Copeland NG. Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells. Blood 106(12):3932-9, 2005. e-Pub 2005. PMID: 16109773.
Jankowsky JL, Slunt HH, Gonzales V, Savonenko AV, Wen JC, Jenkins NA, Copeland NG, Younkin LH, Lester HA, Younkin SG, Borchelt DR. Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease. PLoS Med 2(12):e355, 2005. e-Pub 2005. PMID: 16279840.
Wang J, Xu G, Slunt HH, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA. Neurobiol Dis 20(3):943-52, 2005. e-Pub 2005. PMID: 16046140.
Du Y, Spence SE, Jenkins NA, Copeland NG. Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis. Blood 106(7):2498-505, 2005. e-Pub 2005. PMID: 15961513.
Keng VW, Yae K, Hayakawa T, Mizuno S, Uno Y, Yusa K, Kokubu C, Kinoshita T, Akagi K, Jenkins NA, Copeland NG, Horie K, Takeda J. Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system. Nat Methods 2(10):763-9, 2005. e-Pub 2005. PMID: 16179923.
Zhang XM, Chen BY, Ng AH, Tanner JA, Tay D, So KF, Rachel RA, Copeland NG, Jenkins NA, Huang JD. Transgenic mice expressing Cre-recombinase specifically in retinal rod bipolar neurons. Invest Ophthalmol Vis Sci 46(10):3515-20, 2005. e-Pub 2005. PMID: 16186328.
Wang J, Xu G, Li H, Gonzales V, Fromholt D, Karch C, Copeland NG, Jenkins NA, Borchelt DR. Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation. Hum Mol Genet 14(16):2335-47, 2005. e-Pub 2005. PMID: 16000321.
Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature 436(7048):221-6, 2005. e-Pub 2005. PMID: 16015321.
Tsang S, Sun Z, Luke B, Stewart C, Lum N, Gregory M, Wu X, Subleski M, Jenkins NA, Copeland NG, Munroe DJ. A comprehensive SNP-based genetic analysis of inbred mouse strains. Mamm Genome 16(7):476-80, 2005. e-Pub 2005. PMID: 16151692.
Tyska MJ, Mackey AT, Huang JD, Copeland NG, Jenkins NA, Mooseker MS. Myosin-1a is critical for normal brush border structure and composition. Mol Biol Cell 16(5):2443-57, 2005. e-Pub 2005. PMID: 15758024.
Warming S, Costantino N, Court DL, Jenkins NA, Copeland NG. Simple and highly efficient BAC recombineering using galK selection. Nucleic Acids Res 33(4):e36, 2005. e-Pub 2005. PMID: 15731329.
Iwasaki M, Kuwata T, Yamazaki Y, Jenkins NA, Copeland NG, Osato M, Ito Y, Kroon E, Sauvageau G, Nakamura T. Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood 105(2):784-93, 2005. e-Pub 2005. PMID: 15454493.
O'Sullivan TN, Wu XS, Rachel RA, Huang JD, Swing DA, Matesic LE, Hammer JA 3rd, Copeland NG, Jenkins NA. dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice. Proc Natl Acad Sci U S A 101(48):16831-6, 2004. e-Pub 2004. PMID: 15550542.
Goti D, Katzen SM, Mez J, Kurtis N, Kiluk J, Ben-Haiem L, Jenkins NA, Copeland NG, Kakizuka A, Sharp AH, Ross CA, Mouton PR, Colomer V. A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration. J Neurosci 24(45):10266-79, 2004. e-Pub 2004. PMID: 15537899.
Zhang XM, Ng AH, Tanner JA, Wu WT, Copeland NG, Jenkins NA, Huang JD. Highly restricted expression of Cre recombinase in cerebellar Purkinje cells. Genesis 40(1):45-51, 2004. e-Pub 2004. PMID: 15354293.
Schilling G, Savonenko AV, Klevytska A, Morton JL, Tucker SM, Poirier M, Gale A, Chan N, Gonzales V, Slunt HH, Coonfield ML, Jenkins NA, Copeland NG, Ross CA, Borchelt DR. Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice. Hum Mol Genet 13(15):1599-610, 2004. e-Pub 2004. PMID: 15190011.
Jankowsky JL, Slunt HH, Gonzales V, Jenkins NA, Copeland NG, Borchelt DR. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1. Neurobiol Aging 25(7):885-92, 2004. e-Pub 2004. PMID: 15212842.
Warming S, Suzuki T, Yamaguchi TP, Jenkins NA, Copeland NG. Early B-cell factor-associated zinc-finger gene is a frequent target of retroviral integration in murine B-cell lymphomas. Oncogene 23(15):2727-31, 2004. e-Pub 2004. PMID: 15048087.
Turcotte K, Gauthier S, Mitsos LM, Shustik C, Copeland NG, Jenkins NA, Fournet JC, Jolicoeur P, Gros P. Genetic control of myeloproliferation in BXH-2 mice. Blood 103(6):2343-50, 2004. e-Pub 2004. PMID: 14630819.
Hisa T, Spence SE, Rachel RA, Fujita M, Nakamura T, Ward JM, Devor-Henneman DE, Saiki Y, Kutsuna H, Tessarollo L, Jenkins NA, Copeland NG. Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J 23(2):450-9, 2004. e-Pub 2004. PMID: 14713950.
Dave UP, Jenkins NA, Copeland NG. Gene therapy insertional mutagenesis insights. Science 303(5656):333, 2004. e-Pub 2004. PMID: 14726584.
Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, Jenkins NA, Copeland NG, Lee MK, Younkin LH, Wagner SL, Younkin SG, Borchelt DR. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet 13(2):159-70, 2004. e-Pub 2004. PMID: 14645205.
Akagi K, Suzuki T, Stephens RM, Jenkins NA, Copeland NG. RTCGD: retroviral tagged cancer gene database. Nucleic Acids Res 32(Database issue):D523-7, 2004. e-Pub 2004. PMID: 14681473.
Wang J, Slunt H, Gonzales V, Fromholt D, Coonfield M, Copeland NG, Jenkins NA, Borchelt DR. Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature. Hum Mol Genet 12(21):2753-64, 2003. e-Pub 2003. PMID: 12966034.
Li W, Zhang Q, Oiso N, Novak EK, Gautam R, O'Brien EP, Tinsley CL, Blake DJ, Spritz RA, Copeland NG, Jenkins NA, Amato D, Roe BA, Starcevic M, Dell'Angelica EC, Elliott RW, Mishra V, Kingsmore SF, Paylor RE, Swank RT. Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Nat Genet 35(1):84-9, 2003. e-Pub 2003. PMID: 12923531.
Kumagai H, Oki T, Tamitsu K, Feng SZ, Ono M, Nakajima H, Bao YC, Kawakami Y, Nagayoshi K, Copeland NG, Gilbert DJ, Jenkins NA, Kawakami T, Kitamura T. Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells. Biochem Biophys Res Commun 307(3):719-29, 2003. e-Pub 2003. PMID: 12893283.
Kelly JA, Spolski R, Kovanen PE, Suzuki T, Bollenbacher J, Pise-Masison CA, Radonovich MF, Lee S, Jenkins NA, Copeland NG, Morse HC 3rd, Leonard WJ. Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma. J Exp Med 198(1):79-89, 2003. e-Pub 2003. PMID: 12835478.
Boulanger A, McLemore P, Copeland NG, Gilbert DJ, Jenkins NA, Yu SS, Gentleman S, Redmond TM. Identification of beta-carotene 15, 15'-monooxygenase as a peroxisome proliferator-activated receptor target gene. FASEB J 17(10):1304-6, 2003. e-Pub 2003. PMID: 12759335.
Liu P, Keller JR, Ortiz M, Tessarollo L, Rachel RA, Nakamura T, Jenkins NA, Copeland NG. Bcl11a is essential for normal lymphoid development. Nat Immunol 4(6):525-32, 2003. e-Pub 2003. PMID: 12717432.
Montcouquiol M, Rachel RA, Lanford PJ, Copeland NG, Jenkins NA, Kelley MW. Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 423(6936):173-7, 2003. e-Pub 2003. PMID: 12724779.
Wiltshire T, Pletcher MT, Batalov S, Barnes SW, Tarantino LM, Cooke MP, Wu H, Smylie K, Santrosyan A, Copeland NG, Jenkins NA, Kalush F, Mural RJ, Glynne RJ, Kay SA, Adams MD, Fletcher CF. Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc Natl Acad Sci U S A 100(6):3380-5, 2003. e-Pub 2003. PMID: 12612341.
Warming S, Liu P, Suzuki T, Akagi K, Lindtner S, Pavlakis GN, Jenkins NA, Copeland NG. Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Kruppel-like zinc finger protein. Blood 101(5):1934-40, 2003. e-Pub 2003. PMID: 12393497.
Liu P, Jenkins NA, Copeland NG. A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res 13(3):476-84, 2003. e-Pub 2003. PMID: 12618378.
Zhang Q, Zhao B, Li W, Oiso N, Novak EK, Rusiniak ME, Gautam R, Chintala S, O'Brien EP, Zhang Y, Roe BA, Elliott RW, Eicher EM, Liang P, Kratz C, Legius E, Spritz RA, O'Sullivan TN, Copeland NG, Jenkins NA, Swank RT. Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6. Nat Genet 33(2):145-53, 2003. e-Pub 2003. PMID: 12548288.
Kim R, Trubetskoy A, Suzuki T, Jenkins NA, Copeland NG, Lenz J. Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas. J Virol 77(3):2056-62, 2003. e-Pub 2003. PMID: 12525640.
Angelats C, Wang XW, Jermiin LS, Copeland NG, Jenkins NA, Baker RT. Isolation and characterization of the mouse ubiquitin-specific protease Usp15. Mamm Genome 14(1):31-46, 2003. e-Pub 2003. PMID: 12532266.
Shen H, Suzuki T, Munroe DJ, Stewart C, Rasmussen L, Gilbert DJ, Jenkins NA, Copeland NG. Common sites of retroviral integration in mouse hematopoietic tumors identified by high-throughput, single nucleotide polymorphism-based mapping and bacterial artificial chromosome hybridization. J Virol 77(2):1584-8, 2003. e-Pub 2003. PMID: 12502872.
Steingrimsson E, Arnheiter H, Hallsson JH, Lamoreux ML, Copeland NG, Jenkins NA. Interallelic complementation at the mouse Mitf locus. Genetics 163(1):267-76, 2003. e-Pub 2003. PMID: 12586714.
Wilson SM, Bhattacharyya B, Rachel RA, Coppola V, Tessarollo L, Householder DB, Fletcher CF, Miller RJ, Copeland NG, Jenkins NA. Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease. Nat Genet 32(3):420-5, 2002. e-Pub 2002. PMID: 12368914.
Kawai T, Suzuki Y, Eda S, Kase T, Ohtani K, Sakai Y, Keshi H, Fukuoh A, Sakamoto T, Nozaki M, Copeland NG, Jenkins NA, Wakamiya N. Molecular cloning of mouse collectin liver 1. Biosci Biotechnol Biochem 66(10):2134-45, 2002. e-Pub 2002. PMID: 12450124.
Chen AJ, Zhou G, Juan T, Colicos SM, Cannon JP, Cabriera-Hansen M, Meyer CF, Jurecic R, Copeland NG, Gilbert DJ, Jenkins NA, Fletcher F, Tan TH, Belmont JW. The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway. J Biol Chem 277(39):36592-601, 2002. e-Pub 2002. PMID: 12138158.
Suzuki T, Shen H, Akagi K, Morse HC, Malley JD, Naiman DQ, Jenkins NA, Copeland NG. New genes involved in cancer identified by retroviral tagging. Nat Genet 32(1):166-74, 2002. e-Pub 2002. PMID: 12185365.
Kone J, Arroyo J, Savinelli T, Lin S, Boyd K, Wu Y, Nimmakayalu M, Copeland NG, Jenkins NA, Qumsiyeh M, Hu P, Prescott A, Wu H, Yang L, Roe B, Perkins AS. F-MuLV acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4. Leukemia 16(9):1827-34, 2002. e-Pub 2002. PMID: 12200699.
Novak EK, Gautam R, Reddington M, Collinson LM, Copeland NG, Jenkins NA, McGarry MP, Swank RT. The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granule-specific and dependent on genetic background. Blood 100(1):128-35, 2002. e-Pub 2002. PMID: 12070017.
Wang J, Xu G, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR. Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site. Neurobiol Dis 10(2):128-38, 2002. e-Pub 2002. PMID: 12127151.
Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins NA, Price DL. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proc Natl Acad Sci U S A 99(13):8968-73, 2002. e-Pub 2002. PMID: 12084935.
Arlotta P, Miyazaki D, Copeland NG, Gilbert DJ, Jenkins NA, Ono SJ. Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression. Immunology 106(2):173-81, 2002. e-Pub 2002. PMID: 12047746.
Copeland NG, Jenkins NA, O'Brien SJ. Genomics. Mmu 16--comparative genomic highlights. Science 296(5573):1617-8, 2002. e-Pub 2002. PMID: 12040165.
Iglesias JM, Morgan RO, Jenkins NA, Copeland NG, Gilbert DJ, Fernandez MP. Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins. Mol Biol Evol 19(5):608-18, 2002. e-Pub 2002. PMID: 11961095.
Himmel KL, Bi F, Shen H, Jenkins NA, Copeland NG, Zheng Y, Largaespada DA. Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias. J Biol Chem 277(16):13463-72, 2002. e-Pub 2002. PMID: 11839748.
Steingrimsson E, Tessarollo L, Pathak B, Hou L, Arnheiter H, Copeland NG, Jenkins NA. Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development. Proc Natl Acad Sci U S A 99(7):4477-82, 2002. e-Pub 2002. PMID: 11930005.
Wu XS, Rao K, Zhang H, Wang F, Sellers JR, Matesic LE, Copeland NG, Jenkins NA, Hammer JA 3rd. Identification of an organelle receptor for myosin-Va. Nat Cell Biol 4(4):271-8, 2002. e-Pub 2002. PMID: 11887186.
Borchelt DR, Lee MK, Gonzales V, Slunt HH, Ratovitski T, Jenkins NA, Copeland NG, Price DL, Sisodia SS. Accumulation of proteolytic fragments of mutant presenilin 1 and accelerated amyloid deposition are co-regulated in transgenic mice. Neurobiol Aging 23(2):171-7, 2002. e-Pub 2002. PMID: 11804700.
Bramblett DE, Copeland NG, Jenkins NA, Tsai MJ. BHLHB4 is a bHLH transcriptional regulator in pancreas and brain that marks the dimesencephalic boundary. Genomics 79(3):402-12, 2002. e-Pub 2002. PMID: 11863370.
Shima Y, Copeland NG, Gilbert DJ, Jenkins NA, Chisaka O, Takeichi M, Uemura T. Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development. Dev Dyn 223(3):321-32, 2002. e-Pub 2002. PMID: 11891983.
Sierra DA, Gilbert DJ, Householder D, Grishin NV, Yu K, Ukidwe P, Barker SA, He W, Wensel TG, Otero G, Brown G, Copeland NG, Jenkins NA, Wilkie TM. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics 79(2):177-85, 2002. e-Pub 2002. PMID: 11829488.
Nadano D, Sugihara K, Paria BC, Saburi S, Copeland NG, Gilbert DJ, Jenkins NA, Nakayama J, Fukuda MN. Significant differences between mouse and human trophinins are revealed by their expression patterns and targeted disruption of mouse trophinin gene. Biol Reprod 66(2):313-21, 2002. e-Pub 2002. PMID: 11804944.
Liu P, Jenkins NA, Copeland NG. Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells. Nat Genet 30(1):66-72, 2002. e-Pub 2002. PMID: 11740496.
Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic DB, Keck-Waggoner CL, Popescu NC, Kimura S. Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family. Cytogenet Genome Res 97(1-2):120-7, 2002. e-Pub 2002. PMID: 12438750.
Hui Y, Yang G, Galczenski H, Figueroa DJ, Austin CP, Copeland NG, Gilbert DJ, Jenkins NA, Funk CD. The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization. J Biol Chem 276(50):47489-95, 2001. e-Pub 2001. PMID: 11591709.
Brannan CI, Disteche CM, Park LS, Copeland NG, Jenkins NA. Autosomal telomere exchange results in the rapid amplification and dispersion of Csf2ra genes in wild-derived mice. Mamm Genome 12(12):882-6, 2001. e-Pub 2001. PMID: 11707773.
Opavsky R, Haviernik P, Jurkovicova D, Garin MT, Copeland NG, Gilbert DJ, Jenkins NA, Bies J, Garfield S, Pastorekova S, Oue A, Wolff L. Molecular characterization of the mouse Tem1/endosialin gene regulated by cell density in vitro and expressed in normal tissues in vivo. J Biol Chem 276(42):38795-807, 2001. e-Pub 2001. PMID: 11489895.
Blaydes SM, Kogan SC, Truong BT, Gilbert DJ, Jenkins NA, Copeland NG, Largaespada DA, Brannan CI. Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute myeloid leukemia. J Virol 75(19):9427-34, 2001. e-Pub 2001. PMID: 11533205.
Lu X, Gruia-Gray J, Copeland NG, Gilbert DJ, Jenkins NA, Londos C, Kimmel AR. The murine perilipin gene: the lipid droplet-associated perilipins derive from tissue-specific, mRNA splice variants and define a gene family of ancient origin. Mamm Genome 12(9):741-9, 2001. e-Pub 2001. PMID: 11641724.
Nili E, Cojocaru GS, Kalma Y, Ginsberg D, Copeland NG, Gilbert DJ, Jenkins NA, Berger R, Shaklai S, Amariglio N, Brok-Simoni F, Simon AJ, Rechavi G. Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less). J Cell Sci 114(Pt 18):3297-307, 2001. e-Pub 2001. PMID: 11591818.
Davids MS, Crawford E, Weremowicz S, Morton CC, Copeland NG, Gilbert DJ, Jenkins NA, Phelan MC, Comb MJ, Melnick MB. STK25 is a candidate gene for pseudopseudohypoparathyroidism. Genomics 77(1-2):2-4, 2001. e-Pub 2001. PMID: 11543625.
Matesic LE, Yip R, Reuss AE, Swing DA, O'Sullivan TN, Fletcher CF, Copeland NG, Jenkins NA. Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice. Proc Natl Acad Sci U S A 98(18):10238-43, 2001. e-Pub 2001. PMID: 11504925.
Hu B, Copeland NG, Gilbert DJ, Jenkins NA, Kilimann MW. The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative. Biochem Biophys Res Commun 285(5):1369-76, 2001. e-Pub 2001. PMID: 11478809.
Morse HC 3rd, Qi CF, Chattopadhyay SK, Hori M, Taddesse-Heath L, Ozato K, Hartley JW, Taylor BA, Ward JM, Jenkins NA, Copeland NG, Fredrickson TN. Combined histologic and molecular features reveal previously unappreciated subsets of lymphoma in AKXD recombinant inbred mice. Leuk Res 25(8):719-33, 2001. e-Pub 2001. PMID: 11397479.
Morroll S, Goodchild M, Salmon N, Copeland NG, Gilbert DJ, Jenkins NA, Bumstead N, Boyd Y. The genes encoding E-selectin (SELE) and lymphotactin (SCYC1) lie on separate chicken chromosomes although they are closely linked in human and mouse. Immunogenetics 53(6):477-82, 2001. e-Pub 2001. PMID: 11685458.
Nishinakamura R, Matsumoto Y, Nakao K, Nakamura K, Sato A, Copeland NG, Gilbert DJ, Jenkins NA, Scully S, Lacey DL, Katsuki M, Asashima M, Yokota T. Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development 128(16):3105-15, 2001. e-Pub 2001. PMID: 11688560.
Pyrski M, Xu Z, Walters E, Gilbert DJ, Jenkins NA, Copeland NG, Margolis FL. The OMP-lacZ transgene mimics the unusual expression pattern of OR-Z6, a new odorant receptor gene on mouse chromosome 6: implication for locus-dependent gene expression. J Neurosci 21(13):4637-48, 2001. e-Pub 2001. PMID: 11425891.
Fujino T, Yamazaki Y, Largaespada DA, Jenkins NA, Copeland NG, Hirokawa K, Nakamura T. Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes. Exp Hematol 29(7):856-63, 2001. e-Pub 2001. PMID: 11438208.
Kojima T, Yoshikawa Y, Takada S, Sato M, Nakamura T, Takahashi N, Copeland NG, Gilbert DJ, Jenkins NA, Mori N. Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135. Biochem Biophys Res Commun 284(4):1039-47, 2001. e-Pub 2001. PMID: 11409899.
Leasure CS, Chandler J, Gilbert DJ, Householder DB, Stephens R, Copeland NG, Jenkins NA, Sharan SK. Sequence, chromosomal location and expression analysis of the murine homologue of human RAD51L2/RAD51C. Gene 271(1):59-67, 2001. e-Pub 2001. PMID: 11410366.
Wilson SM, Householder DB, Coppola V, Tessarollo L, Fritzsch B, Lee EC, Goss D, Carlson GA, Copeland NG, Jenkins NA. Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice. Genomics 74(2):228-33, 2001. e-Pub 2001. PMID: 11386759.
Jankowsky JL, Slunt HH, Ratovitski T, Jenkins NA, Copeland NG, Borchelt DR. Co-expression of multiple transgenes in mouse CNS: a comparison of strategies. Biomol Eng 17(6):157-65, 2001. e-Pub 2001. PMID: 11337275.
Latinkic BV, Mo FE, Greenspan JA, Copeland NG, Gilbert DJ, Jenkins NA, Ross SR, Lau LF. Promoter function of the angiogenic inducer Cyr61gene in transgenic mice: tissue specificity, inducibility during wound healing, and role of the serum response element. Endocrinology 142(6):2549-57, 2001. e-Pub 2001. PMID: 11356704.
Palmer S, Groves N, Schindeler A, Yeoh T, Biben C, Wang CC, Sparrow DB, Barnett L, Jenkins NA, Copeland NG, Koentgen F, Mohun T, Harvey RP. The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner. J Cell Biol 153(5):985-98, 2001. e-Pub 2001. PMID: 11381084.
Fletcher CF, Tottene A, Lennon VA, Wilson SM, Dubel SJ, Paylor R, Hosford DA, Tessarollo L, McEnery MW, Pietrobon D, Copeland NG, Jenkins NA. Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity. FASEB J 15(7):1288-90, 2001. e-Pub 2001. PMID: 11344116.
Dupuy AJ, Morgan K, von Lintig FC, Shen H, Acar H, Hasz DE, Jenkins NA, Copeland NG, Boss GR, Largaespada DA. Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia. J Biol Chem 276(15):11804-11, 2001. e-Pub 2001. PMID: 11278453.
Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, Court DL, Jenkins NA, Copeland NG. A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73(1):56-65, 2001. e-Pub 2001. PMID: 11352566.
Dass B, McMahon KW, Jenkins NA, Gilbert DJ, Copeland NG, MacDonald CC. The gene for a variant form of the polyadenylation protein CstF-64 is on chromosome 19 and is expressed in pachytene spermatocytes in mice. J Biol Chem 276(11):8044-50, 2001. e-Pub 2001. PMID: 11113135.
Wu X, Rao K, Bowers MB, Copeland NG, Jenkins NA, Hammer JA 3rd. Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle. J Cell Sci 114(Pt 6):1091-100, 2001. e-Pub 2001. PMID: 11228153.
Tidhar A, Reichenstein M, Cohen D, Faerman A, Copeland NG, Gilbert DJ, Jenkins NA, Shani M. A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells. Dev Dyn 220(1):60-73, 2001. e-Pub 2001. PMID: 11146508.
Hori M, Xiang S, Qi CF, Chattopadhyay SK, Fredrickson TN, Hartley JW, Kovalchuk AL, Bornkamm GW, Janz S, Copeland NG, Jenkins NA, Ward JM, Morse HC 3rd. Non-Hodgkin lymphomas of mice. Blood Cells Mol Dis 27(1):217-22, 2001. e-Pub 2001. PMID: 11358382.
Liang SX, Jenkins NA, Gilbert DJ, Copeland NG, Phillips WD. Structure and chromosome location of the mouse P2X(1) purinoceptor gene (P2rx1). Cytogenet Cell Genet 92(3-4):333-6, 2001. e-Pub 2001. PMID: 11435708.
Dumitru CD, Ceci JD, Tsatsanis C, Kontoyiannis D, Stamatakis K, Lin JH, Patriotis C, Jenkins NA, Copeland NG, Kollias G, Tsichlis PN. TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 103(7):1071-83, 2000. e-Pub 2000. PMID: 11163183.
Wilson SM, Toth PT, Oh SB, Gillard SE, Volsen S, Ren D, Philipson LH, Lee EC, Fletcher CF, Tessarollo L, Copeland NG, Jenkins NA, Miller RJ. The status of voltage-dependent calcium channels in alpha 1E knock-out mice. J Neurosci 20(23):8566-71, 2000. e-Pub 2000. PMID: 11102459.
Robb L, Hartley L, Begley CG, Brodnicki TC, Copeland NG, Gilbert DJ, Jenkins NA, Elefanty AG. Cloning, expression analysis, and chromosomal localization of murine and human homologues of a Xenopus mix gene. Dev Dyn 219(4):497-504, 2000. e-Pub 2000. PMID: 11084649.
Ostendorff HP, Bossenz M, Mincheva A, Copeland NG, Gilbert DJ, Jenkins NA, Lichter P, Bach I. Functional characterization of the gene encoding RLIM, the corepressor of LIM homeodomain factors. Genomics 69(1):120-30, 2000. e-Pub 2000. PMID: 11013082.
Tanaka M, Komuro I, Inagaki H, Jenkins NA, Copeland NG, Izumo S. Nkx3.1, a murine homolog of Ddrosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands. Dev Dyn 219(2):248-60, 2000. e-Pub 2000. PMID: 11002344.
Sims JE, Williams DE, Morrissey PJ, Garka K, Foxworthe D, Price V, Friend SL, Farr A, Bedell MA, Jenkins NA, Copeland NG, Grabstein K, Paxton RJ. Molecular cloning and biological characterization of a novel murine lymphoid growth factor. J Exp Med 192(5):671-80, 2000. e-Pub 2000. PMID: 10974033.
Park LS, Martin U, Garka K, Gliniak B, Di Santo JP, Muller W, Largaespada DA, Copeland NG, Jenkins NA, Farr AG, Ziegler SF, Morrissey PJ, Paxton R, Sims JE. Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor. J Exp Med 192(5):659-70, 2000. e-Pub 2000. PMID: 10974032.
Osawa M, Miyoshi S, Copeland NG, Gilbert DJ, Jenkins NA, Hiroyama T, Motohashi T, Nakamura Y, Iwama A, Nakauchi H. Characterization of the mouse interleukin-13 receptor alpha1 gene. Immunogenetics 51(11):974-81, 2000. e-Pub 2000. PMID: 11003391.
Mori Y, Wakamori M, Oda S, Fletcher CF, Sekiguchi N, Mori E, Copeland NG, Jenkins NA, Matsushita K, Matsuyama Z, Imoto K. Reduced voltage sensitivity of activation of P/Q-type Ca2+ channels is associated with the ataxic mouse mutation rolling Nagoya (tg(rol)). J Neurosci 20(15):5654-62, 2000. e-Pub 2000. PMID: 10908603.
Acar H, Copeland NG, Gilbert DJ, Jenkins NA, Largaespada DA. Detection of integrated murine leukemia viruses in a mouse model of acute myeloid leukemia by fluorescence in situ hybridization combined with tyramide signal amplification. Cancer Genet Cytogenet 121(1):44-51, 2000. e-Pub 2000. PMID: 10958940.
von Bulow GU, Russell H, Copeland NG, Gilbert DJ, Jenkins NA, Bram RJ. Molecular cloning and functional characterization of murine transmembrane activator and CAML interactor (TACI) with chromosomal localization in human and mouse. Mamm Genome 11(8):628-32, 2000. e-Pub 2000. PMID: 10920230.
Wang W, Soto H, Oldham ER, Buchanan ME, Homey B, Catron D, Jenkins N, Copeland NG, Gilbert DJ, Nguyen N, Abrams J, Kershenovich D, Smith K, McClanahan T, Vicari AP, Zlotnik A. Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2). J Biol Chem 275(29):22313-23, 2000. e-Pub 2000. PMID: 10781587.
Huang K, Johnson KD, Petcherski AG, Vandergon T, Mosser EA, Copeland NG, Jenkins NA, Kimble J, Bresnick EH. A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis. Gene 252(1-2):137-45, 2000. e-Pub 2000. PMID: 10903445.
Kojima T, Morikawa Y, Copeland NG, Gilbert DJ, Jenkins NA, Senba E, Kitamura T. TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles. J Biol Chem 275(27):20742-7, 2000. e-Pub 2000. PMID: 10764796.
Wilson SM, Yip R, Swing DA, O'Sullivan TN, Zhang Y, Novak EK, Swank RT, Russell LB, Copeland NG, Jenkins NA. A mutation in Rab27a causes the vesicle transport defects observed in ashen mice. Proc Natl Acad Sci U S A 97(14):7933-8, 2000. e-Pub 2000. PMID: 10859366.
Britton RA, Chen SM, Wallis D, Koeuth T, Powell BS, Shaffer LG, Largaespada D, Jenkins NA, Copeland NG, Court DL, Lupski JR. Isolation and preliminary characterization of the human and mouse homologues of the bacterial cell cycle gene era. Genomics 67(1):78-82, 2000. e-Pub 2000. PMID: 10945472.
Sakao Y, Kawai T, Takeuchi O, Copeland NG, Gilbert DJ, Jenkins NA, Takeda K, Akira S. Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting. Genomics 67(1):1-7, 2000. e-Pub 2000. PMID: 10945464.
Wang CC, Brodnicki T, Copeland NG, Jenkins NA, Harvey RP. Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals. Mamm Genome 11(6):466-8, 2000. e-Pub 2000. PMID: 10818213.
Sleckman BP, Khan WN, Xu W, Bassing CH, Malynn BA, Copeland NG, Bardon CG, Breit TM, Davidson L, Oltz EM, Jenkins NA, Berman JE, Alt FW. Cloning and functional characterization of the early-lymphocyte-specific Pb99 gene. Mol Cell Biol 20(12):4405-10, 2000. e-Pub 2000. PMID: 10825203.
Yu D, Ellis HM, Lee EC, Jenkins NA, Copeland NG, Court DL. An efficient recombination system for chromosome engineering in Escherichia coli. Proc Natl Acad Sci U S A 97(11):5978-83, 2000. e-Pub 2000. PMID: 10811905.
Parker RM, Copeland NG, Eyre HJ, Liu M, Gilbert DJ, Crawford J, Couzens M, Sutherland GR, Jenkins NA, Herzog H. Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. Brain Res Mol Brain Res 77(2):199-208, 2000. e-Pub 2000. PMID: 10837915.
Hallsson JH, Favor J, Hodgkinson C, Glaser T, Lamoreux ML, Magnusdottir R, Gunnarsson GJ, Sweet HO, Copeland NG, Jenkins NA, Steingrimsson E. Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus. Genetics 155(1):291-300, 2000. e-Pub 2000. PMID: 10790403.
Bosse A, Stoykova A, Nieselt-Struwe K, Chowdhury K, Copeland NG, Jenkins NA, Gruss P. Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family. Dev Dyn 218(1):160-74, 2000. e-Pub 2000. PMID: 10822268.
Piras G, El Kharroubi A, Kozlov S, Escalante-Alcalde D, Hernandez L, Copeland NG, Gilbert DJ, Jenkins NA, Stewart CL. Zac1 (Lot1), a potential tumor suppressor gene, and the gene for epsilon-sarcoglycan are maternally imprinted genes: identification by a subtractive screen of novel uniparental fibroblast lines. Mol Cell Biol 20(9):3308-15, 2000. e-Pub 2000. PMID: 10757814.
Kennedy J, Vicari AP, Saylor V, Zurawski SM, Copeland NG, Gilbert DJ, Jenkins NA, Zlotnik A. A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). J Leukoc Biol 67(5):725-34, 2000. e-Pub 2000. PMID: 10811014.
Nakamura T, Yamazaki Y, Saiki Y, Moriyama M, Largaespada DA, Jenkins NA, Copeland NG. Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product. Mol Cell Biol 20(9):3178-86, 2000. e-Pub 2000. PMID: 10757802.
Parker R, Liu M, Eyre HJ, Copeland NG, Gilbert DJ, Crawford J, Sutherland GR, Jenkins NA, Herzog H. Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6. Biochim Biophys Acta 1491(1-3):369-75, 2000. e-Pub 2000. PMID: 10760605.
Tian E, Sawyer JR, Largaespada DA, Jenkins NA, Copeland NG, Shaughnessy JD Jr. Evi27 encodes a novel membrane protein with homology to the IL17 receptor. Oncogene 19(17):2098-109, 2000. e-Pub 2000. PMID: 10815801.
Fujio K, Nosaka T, Kojima T, Kawashima T, Yahata T, Copeland NG, Gilbert DJ, Jenkins NA, Yamamoto K, Nishimura T, Kitamura T. Molecular cloning of a novel type 1 cytokine receptor similar to the common gamma chain. Blood 95(7):2204-10, 2000. e-Pub 2000. PMID: 10733486.
Jones JM, Huang JD, Mermall V, Hamilton BA, Mooseker MS, Escayg A, Copeland NG, Jenkins NA, Meisler MH. The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a. Hum Mol Genet 9(5):821-8, 2000. e-Pub 2000. PMID: 10749990.
Montano AM, Yamagishi A, Tomatsu S, Fukuda S, Copeland NG, Orii KE, Isogai K, Yamada N, Kato ZI, Jenkins NA, Gilbert DJ, Sukegawa K, Orii T, Kondo N. The mouse N-acetylgalactosamine-6-sulfate sulfatase (Galns) gene: cDNA isolation, genomic characterization, chromosomal assignment and analysis of the 5'-flanking region. Biochim Biophys Acta 1500(3):323-34, 2000. e-Pub 2000. PMID: 10699374.
Sorensen AB, Lund AH, Ethelberg S, Copeland NG, Jenkins NA, Pedersen FS. Sint1, a common integration site in SL3-3-induced T-cell lymphomas, harbors a putative proto-oncogene with homology to the septin gene family. J Virol 74(5):2161-8, 2000. e-Pub 2000. PMID: 10666245.
Frankfater C, Maus E, Gaal K, Segade F, Copeland NG, Gilbert DJ, Jenkins NA, Shipley JM. Organization of the mouse microfibril-associated glycoprotein-2 (MAGP-2) gene. Mamm Genome 11(3):191-5, 2000. e-Pub 2000. PMID: 10723723.
Quach TT, Mosinger B Jr, Ricard D, Copeland NG, Gilbert DJ, Jenkins NA, Stankoff B, Honnorat J, Belin MF, Kolattukudy P. Collapsin response mediator protein-3/unc-33-like protein-4 gene: organization, chromosomal mapping and expression in the developing mouse brain. Gene 242(1-2):175-82, 2000. e-Pub 2000. PMID: 10721710.
Bounpheng MA, Melnikova IN, Dodds SG, Chen H, Copeland NG, Gilbert DJ, Jenkins NA, Christy BA. Characterization of the mouse JAB1 cDNA and protein. Gene 242(1-2):41-50, 2000. e-Pub 2000. PMID: 10721695.
Gardner HP, Rajan JV, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Marquis ST, Chodosh LA. Cloning, characterization, and chromosomal localization of Pnck, a Ca(2+)/calmodulin-dependent protein kinase. Genomics 63(2):279-88, 2000. e-Pub 2000. PMID: 10673339.
Yabuta N, Fujii T, Copeland NG, Gilbert DJ, Jenkins NA, Nishiguchi H, Endo Y, Toji S, Tanaka H, Nishimune Y, Nojima H. Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts. Genomics 63(2):263-70, 2000. e-Pub 2000. PMID: 10673337.
Gardner HP, Wertheim GB, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Marquis ST, Chodosh LA. Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase. Genomics 63(1):46-59, 2000. e-Pub 2000. PMID: 10662544.
Zhang N, Copeland NG, Gilbert DJ, Jenkins NA, Gridley T. Cloning, expression, and chromosomal localization of a mouse gene homologous to the germ cell migration regulator wunen and to type 2 phosphatidic acid phosphatases. Genomics 63(1):142-4, 2000. e-Pub 2000. PMID: 10662554.
Loh ED, Broussard SR, Liu Q, Copeland NG, Gilbert DJ, Jenkins NA, Kolakowski LF Jr. Chromosomal localization of GPR48, a novel glycoprotein hormone receptor like GPCR, in human and mouse with radiation hybrid and interspecific backcross mapping. Cytogenet Cell Genet 89(1-2):2-5, 2000. e-Pub 2000. PMID: 10894923.
Kleiter N, Artner I, Copeland NG, Gilbert DJ, Jenkins NA, Kratochwil K. Genomic organization and chromosome location of the murine Rpl23 gene. Cytogenet Cell Genet 90(3-4):227-30, 2000. e-Pub 2000. PMID: 11124519.
Zhang Q, Topol LZ, Athanasiou M, Copeland NG, Gilbert DJ, Jenkins NA, Blair DG. Cloning of the murine Drm gene (Cktsf1b1) and characterization of its oncogene suppressible promoter. Cytogenet Cell Genet 89(3-4):242-51, 2000. e-Pub 2000. PMID: 10965135.
Gu Z, Gilbert DJ, Valentine VA, Jenkins NA, Copeland NG, Zambetti GP. The p53-inducible gene EI24/PIG8 localizes to human chromosome 11q23 and the proximal region of mouse chromosome 9. Cytogenet Cell Genet 89(3-4):230-3, 2000. e-Pub 2000. PMID: 10965130.
Adams DJ, van der Weyden L, Kovacic A, Lovicu FJ, Copeland NG, Gilbert DJ, Jenkins NA, Ioannou PA, Morris BJ. Chromosome localization and characterization of the mouse and human zinc finger protein 265 gene. Cytogenet Cell Genet 88(1-2):68-73, 2000. e-Pub 2000. PMID: 10773668.
Hurlin PJ, Steingrimsson E, Copeland NG, Jenkins NA, Eisenman RN. Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif. EMBO J 18(24):7019-28, 1999. e-Pub 1999. PMID: 10601024.
Morales J, Homey B, Vicari AP, Hudak S, Oldham E, Hedrick J, Orozco R, Copeland NG, Jenkins NA, McEvoy LM, Zlotnik A. CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells. Proc Natl Acad Sci U S A 96(25):14470-5, 1999. e-Pub 1999. PMID: 10588729.
Meighan-Mantha RL, Hsu DK, Guo Y, Brown SA, Feng SL, Peifley KA, Alberts GF, Copeland NG, Gilbert DJ, Jenkins NA, Richards CM, Winkles JA. The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J Biol Chem 274(46):33166-76, 1999. e-Pub 1999. PMID: 10551889.
Matsumoto M, Tanaka T, Kaisho T, Sanjo H, Copeland NG, Gilbert DJ, Jenkins NA, Akira S. A novel LPS-inducible C-type lectin is a transcriptional target of NF-IL6 in macrophages. J Immunol 163(9):5039-48, 1999. e-Pub 1999. PMID: 10528209.
Li J, Shen H, Himmel KL, Dupuy AJ, Largaespada DA, Nakamura T, Shaughnessy JD, Jenkins NA, Copeland NG. Leukaemia disease genes: large-scale cloning and pathway predictions. Nat Genet 23(3):348-53, 1999. e-Pub 1999. PMID: 10610183.
Hara T, Nakano Y, Tanaka M, Tamura K, Sekiguchi T, Minehata K, Copeland NG, Jenkins NA, Okabe M, Kogo H, Mukouyama Y, Miyajima A. Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region. Immunity 11(5):567-78, 1999. e-Pub 1999. PMID: 10591182.
O'Brien SJ, Eisenberg JF, Miyamoto M, Hedges SB, Kumar S, Wilson DE, Menotti-Raymond M, Murphy WJ, Nash WG, Lyons LA, Menninger JC, Stanyon R, Wienberg J, Copeland NG, Jenkins NA, Gellin J, Yerle M, Andersson L, Womack J, Broad T, Postlethwait J, Serov O, Bailey E, James MR, Marshall Graves JA, et al.. Genome maps 10. Comparative genomics. Mammalian radiations. Wall chart. Science 286(5439):463-78, 1999. e-Pub 1999. PMID: 10577209.
Keeney S, Baudat F, Angeles M, Zhou ZH, Copeland NG, Jenkins NA, Manova K, Jasin M. A mouse homolog of the Saccharomyces cerevisiae meiotic recombination DNA transesterase Spo11p. Genomics 61(2):170-82, 1999. e-Pub 1999. PMID: 10534402.
Self T, Sobe T, Copeland NG, Jenkins NA, Avraham KB, Steel KP. Role of myosin VI in the differentiation of cochlear hair cells. Dev Biol 214(2):331-41, 1999. e-Pub 1999. PMID: 10525338.
Gilbert DJ, Engel H, Wang X, Grzeschik KH, Copeland NG, Jenkins NA, Kilimann MW. The neurobeachin gene (Nbea) identifies a new region of homology between mouse central chromosome 3 and human chromosome 13q13. Mamm Genome 10(10):1030-1, 1999. e-Pub 1999. PMID: 10501977.
Newton G, Weremowicz S, Morton CC, Jenkins NA, Gilbert DJ, Copeland NG, Lawler J. The thrombospondin-4 gene. Mamm Genome 10(10):1010-6, 1999. e-Pub 1999. PMID: 10501972.
Super HJ, Hasenkrug KJ, Simmons S, Brooks DM, Konzek R, Sarge KD, Morimoto RI, Jenkins NA, Gilbert DJ, Copeland NG, Frankel W, Chesebro B. Fine mapping of the friend retrovirus resistance gene, Rfv3, on mouse chromosome 15. J Virol 73(9):7848-52, 1999. e-Pub 1999. PMID: 10438878.
Pucci ML, Bao Y, Chan B, Itoh S, Lu R, Copeland NG, Gilbert DJ, Jenkins NA, Schuster VL. Cloning of mouse prostaglandin transporter PGT cDNA: species-specific substrate affinities. Am J Physiol 277(3):R734-41, 1999. e-Pub 1999. PMID: 10484490.
Schilling G, Wood JD, Duan K, Slunt HH, Gonzales V, Yamada M, Cooper JK, Margolis RL, Jenkins NA, Copeland NG, Takahashi H, Tsuji S, Price DL, Borchelt DR, Ross CA. Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA. Neuron 24(1):275-86, 1999. e-Pub 1999. PMID: 10677044.
Morgan RO, Jenkins NA, Gilbert DJ, Copeland NG, Balsara BR, Testa JR, Fernandez MP. Novel human and mouse annexin A10 are linked to the genome duplications during early chordate evolution. Genomics 60(1):40-9, 1999. e-Pub 1999. PMID: 10458909.
Kawane K, Fukuyama H, Adachi M, Sakahira H, Copeland NG, Gilbert DJ, Jenkin NA, Nagata S. Structure and promoter analysis of murine CAD and ICAD genes. Cell Death Differ 6(8):745-52, 1999. e-Pub 1999. PMID: 10467348.
Cerretti DP, Poindexter K, Castner BJ, Means G, Copeland NG, Gilbert DJ, Jenkins NA, Black RA, Nelson N. Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25. Cytokine 11(8):541-51, 1999. e-Pub 1999. PMID: 10433800.
Hitzler JK, Witte DP, Jenkins NA, Copeland NG, Gilbert DJ, Naeve CW, Look AT, Morris SW. cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia. Am J Pathol 155(1):53-9, 1999. e-Pub 1999. PMID: 10393836.
Wang H, Copeland NG, Gilbert DJ, Jenkins NA, Tessier-Lavigne M. Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors. J Neurosci 19(12):4938-47, 1999. e-Pub 1999. PMID: 10366627.
Osaki E, Nishina Y, Inazawa J, Copeland NG, Gilbert DJ, Jenkins NA, Ohsugi M, Tezuka T, Yoshida M, Semba K. Identification of a novel Sry-related gene and its germ cell-specific expression. Nucleic Acids Res 27(12):2503-10, 1999. e-Pub 1999. PMID: 10359848.
Kawai T, Nomura F, Hoshino K, Copeland NG, Gilbert DJ, Jenkins NA, Akira S. Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity. Oncogene 18(23):3471-80, 1999. e-Pub 1999. PMID: 10376525.
Wallace AM, Dass B, Ravnik SE, Tonk V, Jenkins NA, Gilbert DJ, Copeland NG, MacDonald CC. Two distinct forms of the 64,000 Mr protein of the cleavage stimulation factor are expressed in mouse male germ cells. Proc Natl Acad Sci U S A 96(12):6763-8, 1999. e-Pub 1999. PMID: 10359786.
Nanda N, Iismaa SE, Copeland NG, Gilbert DJ, Jenkins N, Graham RM, Sutrave P. Organization and chromosomal mapping of mouse Gh/tissue transglutaminase gene (Tgm2). Arch Biochem Biophys 366(1):151-6, 1999. e-Pub 1999. PMID: 10334875.
Hashimoto H, Nishino A, Shintani N, Hagihara N, Copeland NG, Jenkins NA, Yamamoto K, Matsuda T, Ishihara T, Nagata S, Baba A. Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1 (VPAC1) receptor. Genomics 58(1):90-3, 1999. e-Pub 1999. PMID: 10331949.
Caddick SJ, Wang C, Fletcher CF, Jenkins NA, Copeland NG, Hosford DA. Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami. J Neurophysiol 81(5):2066-74, 1999. e-Pub 1999. PMID: 10322048.
Valk PJ, Vankan Y, Joosten M, Jenkins NA, Copeland NG, Lowenberg B, Delwel R. Retroviral insertions in Evi12, a novel common virus integration site upstream of Tra1/Grp94, frequently coincide with insertions in the gene encoding the peripheral cannabinoid receptor Cnr2. J Virol 73(5):3595-602, 1999. e-Pub 1999. PMID: 10196250.
Takeuchi O, Kawai T, Sanjo H, Copeland NG, Gilbert DJ, Jenkins NA, Takeda K, Akira S. TLR6: A novel member of an expanding toll-like receptor family. Gene 231(1-2):59-65, 1999. e-Pub 1999. PMID: 10231569.
Robb L, Brodnicki T, Copeland NG, Gilbert DJ, Jenkins NA, Harvey RP. Assignment of the human helix-loop-helix transcription factor gene musculin/activated B-cell factor-1 (MSC) to chromosome 8q21 and its mouse homologue (Msc) to the proximal region of chromosome 1. Genomics 57(2):318-9, 1999. e-Pub 1999. PMID: 10198176.
Downes GB, Gilbert DJ, Copeland NG, Gautam N, Jenkins NA. Chromosomal mapping of five mouse G protein gamma subunits. Genomics 57(1):173-6, 1999. e-Pub 1999. PMID: 10191100.
Fujii T, Tamura K, Copeland NG, Gilbert DJ, Jenkins NA, Yomogida K, Tanaka H, Nishimune Y, Nojima H, Abiko Y. Sperizin is a murine RING zinc-finger protein specifically expressed in Haploid germ cells. Genomics 57(1):94-101, 1999. e-Pub 1999. PMID: 10191088.
Fletcher CF, Jenkins NA, Copeland NG, Chaudhry AZ, Gronostajski RM. Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals. Mamm Genome 10(4):390-6, 1999. e-Pub 1999. PMID: 10087299.
Ji W, Herron B, Jones JM, Jenkins NA, Gilbert DJ, Copeland NG, Swank R, Flaherty L, Meisler MH. Identification of genes within the Krd deletion on mouse chromosome 19. Mamm Genome 10(4):399-401, 1999. e-Pub 1999. PMID: 10087301.
Shaughnessy JD Jr, Largaespada DA, Tian E, Fletcher CF, Cho BC, Vyas P, Jenkins NA, Copeland NG. Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1. Oncogene 18(12):2069-84, 1999. e-Pub 1999. PMID: 10321731.
Valenzuela DM, Griffiths JA, Rojas J, Aldrich TH, Jones PF, Zhou H, McClain J, Copeland NG, Gilbert DJ, Jenkins NA, Huang T, Papadopoulos N, Maisonpierre PC, Davis S, Yancopoulos GD. Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci U S A 96(5):1904-9, 1999. e-Pub 1999. PMID: 10051567.
Fantin VR, Lavan BE, Wang Q, Jenkins NA, Gilbert DJ, Copeland NG, Keller SR, Lienhard GE. Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene. Endocrinology 140(3):1329-37, 1999. e-Pub 1999. PMID: 10067860.
Schilling G, Becher MW, Sharp AH, Jinnah HA, Duan K, Kotzuk JA, Slunt HH, Ratovitski T, Cooper JK, Jenkins NA, Copeland NG, Price DL, Ross CA, Borchelt DR. Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Hum Mol Genet 8(3):397-407, 1999. e-Pub 1999. PMID: 9949199.
Shworak NW, Liu J, Petros LM, Zhang L, Kobayashi M, Copeland NG, Jenkins NA, Rosenberg RD. Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci. J Biol Chem 274(8):5170-84, 1999. e-Pub 1999. PMID: 9988767.
Mao NC, Steingrimsson E, DuHadaway J, Wasserman W, Ruiz JC, Copeland NG, Jenkins NA, Prendergast GC. The murine Bin1 gene functions early in myogenesis and defines a new region of synteny between mouse chromosome 18 and human chromosome 2. Genomics 56(1):51-8, 1999. e-Pub 1999. PMID: 10036185.
Liu M, Parker RM, Darby K, Eyre HJ, Copeland NG, Crawford J, Gilbert DJ, Sutherland GR, Jenkins NA, Herzog H. GPR56, a novel secretin-like human G-protein-coupled receptor gene. Genomics 55(3):296-305, 1999. e-Pub 1999. PMID: 10049584.
Tanaka M, Hara T, Copeland NG, Gilbert DJ, Jenkins NA, Miyajima A. Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit. Blood 93(3):804-15, 1999. e-Pub 1999. PMID: 9920829.
Ho HT, Jenkins NA, Copeland NG, Gilbert DJ, Winkles JA, Louie HW, Lee FK, Chung SS, Chung SK. Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes. Eur J Biochem 259(3):726-30, 1999. e-Pub 1999. PMID: 10092857.
Huang JD, Brady ST, Richards BW, Stenolen D, Resau JH, Copeland NG, Jenkins NA. Direct interaction of microtubule- and actin-based transport motors. Nature 397(6716):267-70, 1999. e-Pub 1999. PMID: 9930703.
Deng X, Copeland NG, Gilbert DJ, Jenkins NA, Martin-DeLeon PA. Assignment of the Zona pellucida 3 receptor (Zp3r) gene to mouse chromosome 1E-F by fluorescence in situ hybridization and confirmation by genetic mapping. Cytogenet Cell Genet 86(3-4):235-6, 1999. e-Pub 1999. PMID: 10575213.
Nakatsu F, Kadohira T, Gilbert DJ, Jenkins NA, Kakuta H, Copeland NG, Saito T, Ohno H. Genomic structure and chromosome mapping of the genes encoding clathrin-associated adaptor medium chains mu1A (Ap1m1) and mu1B (Ap1m2). Cytogenet Cell Genet 87(1-2):53-8, 1999. e-Pub 1999. PMID: 10640811.
Muller U, Grams A, Martinez-Noel G, Copeland NG, Gilbert DJ, Jenkins NA, Harbers K. Structure of the gene encoding the ubiquitin-conjugating enzyme Ubcm4, characterization of its promoter, and chromosomal location. Gene 224(1-2):109-16, 1998. e-Pub 1998. PMID: 9931461.
Jin HM, Copeland NG, Gilbert DJ, Jenkins NA, Kirkpatrick RB, Rosenberg M. Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes. Genomics 54(2):316-22, 1998. e-Pub 1998. PMID: 9828134.
Stairs DB, Perry Gardner H, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Chodosh LA. Cloning and characterization of Krct, a member of a novel subfamily of serine/threonine kinases. Hum Mol Genet 7(13):2157-66, 1998. e-Pub 1998. PMID: 9817935.
Steingrimsson E, Tessarollo L, Reid SW, Jenkins NA, Copeland NG. The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. Development 125(23):4607-16, 1998. e-Pub 1998. PMID: 9806910.
Jiang R, Norton CR, Copeland NG, Gilbert DJ, Jenkins NA, Gridley T. Genomic organization, expression and chromosomal localization of the mouse Slug (Slugh) gene. Biochim Biophys Acta 1443(1-2):251-4, 1998. e-Pub 1998. PMID: 9838149.
Mouri T, Kittaka N, Horio Y, Copeland NG, Gilbert DJ, Jenkins NA, Kurachi Y. Assignment of mouse inwardly rectifying potassium channel Kcnj16 to the distal region of mouse chromosome 11. Genomics 54(1):181-2, 1998. e-Pub 1998. PMID: 9806850.
Fujita A, Horio Y, Copeland NG, Gilbert DJ, Jenkins NA, Kurachi Y. Assignment of mouse cardiac two-pore background K+ channel gene (Kcnk4) to the proximal region of mouse chromosome 5. Genomics 54(1):183-4, 1998. e-Pub 1998. PMID: 9806851.
Schmutte C, Marinescu RC, Copeland NG, Jenkins NA, Overhauser J, Fishel R. Refined chromosomal localization of the mismatch repair and hereditary nonpolyposis colorectal cancer genes hMSH2 and hMSH6. Cancer Res 58(22):5023-6, 1998. e-Pub 1998. PMID: 9823302.
Vestal DJ, Buss JE, McKercher SR, Jenkins NA, Copeland NG, Kelner GS, Asundi VK, Maki RA. Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages. J Interferon Cytokine Res 18(11):977-85, 1998. e-Pub 1998. PMID: 9858320.
Jacobs S, Schurmann A, Becker W, Bockers TM, Copeland NG, Jenkins NA, Joost HG. The mouse ADP-ribosylation factor-like 4 gene: two separate promoters direct specific transcription in tissues and testicular germ cell. Biochem J 335 ( Pt 2)(Pt 2):259-65, 1998. e-Pub 1998. PMID: 9761722.
Wang K, Yin XM, Copeland NG, Gilbert DJ, Jenkins NA, Keck CL, Zimonjic DB, Popescu NC, Korsmeyer SJ. BID, a proapoptotic BCL-2 family member, is localized to mouse chromosome 6 and human chromosome 22q11. Genomics 53(2):235-8, 1998. e-Pub 1998. PMID: 9790773.
Downes GB, Copeland NG, Jenkins NA, Gautam N. Structure and mapping of the G protein gamma3 subunit gene and a divergently transcribed novel gene, gng3lg. Genomics 53(2):220-30, 1998. e-Pub 1998. PMID: 9790771.
Robb L, Mifsud L, Hartley L, Biben C, Copeland NG, Gilbert DJ, Jenkins NA, Harvey RP. epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads. Dev Dyn 213(1):105-13, 1998. e-Pub 1998. PMID: 9733105.
Gabig TG, Crean CD, Klenk A, Long H, Copeland NG, Gilbert DJ, Jenkins NA, Quincey D, Parente F, Lespinasse F, Carle GF, Gaudray P, Zhang CX, Calender A, Hoeppener J, Kas K, Thakker RV, Farnebo F, Teh BT, Larsson C, Piehl F, Lagercrantz J, Khodaei S, Carson E, Weber G. Expression and chromosomal localization of the Requiem gene. Mamm Genome 9(8):660-5, 1998. e-Pub 1998. PMID: 9680388.
Fridolfsson AK, Cheng H, Copeland NG, Jenkins NA, Liu HC, Raudsepp T, Woodage T, Chowdhary B, Halverson J, Ellegren H. Evolution of the avian sex chromosomes from an ancestral pair of autosomes. Proc Natl Acad Sci U S A 95(14):8147-52, 1998. e-Pub 1998. PMID: 9653155.
Kwon YT, Reiss Y, Fried VA, Hershko A, Yoon JK, Gonda DK, Sangan P, Copeland NG, Jenkins NA, Varshavsky A. The mouse and human genes encoding the recognition component of the N-end rule pathway. Proc Natl Acad Sci U S A 95(14):7898-903, 1998. e-Pub 1998. PMID: 9653112.
Soto H, Wang W, Strieter RM, Copeland NG, Gilbert DJ, Jenkins NA, Hedrick J, Zlotnik A. The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3. Proc Natl Acad Sci U S A 95(14):8205-10, 1998. e-Pub 1998. PMID: 9653165.
Hallonet M, Hollemann T, Wehr R, Jenkins NA, Copeland NG, Pieler T, Gruss P. Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain. Development 125(14):2599-610, 1998. e-Pub 1998. PMID: 9636075.
Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiol Dis 5(1):27-35, 1998. e-Pub 1998. PMID: 9702785.
Burwinkel B, Miglierini G, Jenne DE, Gilbert DJ, Copeland NG, Jenkins NA, Ring HZ, Francke U, Kilimann MW. Structure of the human paralemmin gene (PALM), mapping to human chromosome 19p13.3 and mouse chromosome 10, and exclusion of coding mutations in grizzled, mocha, jittery, and hesitant mice. Genomics 49(3):462-6, 1998. e-Pub 1998. PMID: 9615234.
Yang T, Adamson TE, Resnick JL, Leff S, Wevrick R, Francke U, Jenkins NA, Copeland NG, Brannan CI. A mouse model for Prader-Willi syndrome imprinting-centre mutations. Nat Genet 19(1):25-31, 1998. e-Pub 1998. PMID: 9590284.
de Miguel M, Centanni JM, Gopalan G, Gilbert DJ, Copeland NG, Jenkins NA, Donovan PJ. Cellular apoptosis susceptibility gene capts maps to mouse chromosome 2. Mamm Genome 9(5):411-2, 1998. e-Pub 1998. PMID: 9545506.
Stanley E, Gilbert DG, Jenkins NA, Copeland NG, Harvey RP. Murine cerberus homologue Cer1 maps to chromosome 4. Genomics 49(2):337-8, 1998. e-Pub 1998. PMID: 9598328.
Gao X, Copeland NG, Gilbert DJ, Jenkins NA, Gridley T. Assignment of the murine Notch2 and Notch3 genes to chromosomes 3 and 17. Genomics 49(1):160-1, 1998. e-Pub 1998. PMID: 9570965.
Kalyanaraman S, Copeland NG, Gilbert DG, Jenkins NA, Gautam N. Structure and chromosomal localization of mouse G protein subunit gamma 4 gene. Genomics 49(1):147-51, 1998. e-Pub 1998. PMID: 9570961.
Centanni JM, de Miguel M, Gopalan G, Gilbert DJ, Copeland NG, Jenkins NA, Donovan PJ. Interleukin-1 receptor-associated kinase gene Il1rak maps to the mouse X chromosome. Mamm Genome 9(4):340-1, 1998. e-Pub 1998. PMID: 9530638.
Huang JD, Mermall V, Strobel MC, Russell LB, Mooseker MS, Copeland NG, Jenkins NA. Molecular genetic dissection of mouse unconventional myosin-VA: tail region mutations. Genetics 148(4):1963-72, 1998. e-Pub 1998. PMID: 9560409.
Rooney RJ, Daniels RR, Jenkins NA, Gilbert DJ, Rothammer K, Morris SW, Higgs DR, Copeland NG. Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice. Mamm Genome 9(4):320-3, 1998. e-Pub 1998. PMID: 9530632.
Huang JD, Cope MJ, Mermall V, Strobel MC, Kendrick-Jones J, Russell LB, Mooseker MS, Copeland NG, Jenkins NA. Molecular genetic dissection of mouse unconventional myosin-VA: head region mutations. Genetics 148(4):1951-61, 1998. e-Pub 1998. PMID: 9560408.
Oshima H, Nakano H, Nohara C, Kobata T, Nakajima A, Jenkins NA, Gilbert DJ, Copeland NG, Muto T, Yagita H, Okumura K. Characterization of murine CD70 by molecular cloning and mAb. Int Immunol 10(4):517-26, 1998. e-Pub 1998. PMID: 9620608.
Misawa H, Ohtsubo M, Copeland NG, Gilbert DJ, Jenkins NA, Yoshimura A. Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain. Biochem Biophys Res Commun 244(2):531-9, 1998. e-Pub 1998. PMID: 9514948.
Shindo M, Nakano H, Kuroyanagi H, Shirasawa T, Mihara M, Gilbert DJ, Jenkins NA, Copeland NG, Yagita H, Okumura K. cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2. Biochem Biophys Res Commun 244(1):285-92, 1998. e-Pub 1998. PMID: 9514916.
Kalman K, Nguyen A, Tseng-Crank J, Dukes ID, Chandy G, Hustad CM, Copeland NG, Jenkins NA, Mohrenweiser H, Brandriff B, Cahalan M, Gutman GA, Chandy KG. Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7. J Biol Chem 273(10):5851-7, 1998. e-Pub 1998. PMID: 9488722.
Han P, Fletcher CF, Copeland NG, Jenkins NA, Yaremko LM, Michaeli T. Assignment of the mouse Pde7A gene to the proximal region of chromosome 3 and of the human PDE7A gene to chromosome 8q13. Genomics 48(2):275-6, 1998. e-Pub 1998. PMID: 9521885.
Kamata T, Subleski M, Hara Y, Yuhki N, Kung H, Copeland NG, Jenkins NA, Yoshimura T, Modi W, Copeland TD. Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance. Brain Res Mol Brain Res 54(2):219-36, 1998. e-Pub 1998. PMID: 9555025.
Guida LC, Charlton P, Gilbert DJ, Jenkins NA, Copeland NG, Nicholls RD. Genetic mapping of the galanin-GMAP (Galn) gene to mouse chromosome 19. Mamm Genome 9(3):240-2, 1998. e-Pub 1998. PMID: 9501310.
Steingrimsson E, Favor J, Ferre-D'Amare AF, Copeland NG, Jenkins NA. Mitfmi-enu122 is a missense mutation in the HLH dimerization domain. Mamm Genome 9(3):250-2, 1998. e-Pub 1998. PMID: 9501313.
Yamashita T, Agulnick AD, Copeland NG, Gilbert DJ, Jenkins NA, Westphal H. Genomic structure and chromosomal localization of the mouse LIM domain-binding protein 1 gene, Ldb1. Genomics 48(1):87-92, 1998. e-Pub 1998. PMID: 9503020.
Tavner FJ, Simpson R, Tashiro S, Favier D, Jenkins NA, Gilbert DJ, Copeland NG, Macmillan EM, Lutwyche J, Keough RA, Ishii S, Gonda TJ. Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb. Mol Cell Biol 18(2):989-1002, 1998. e-Pub 1998. PMID: 9447996.
Jenkins NA, Gilbert DJ, Copeland NG, Gruzglin E, Bieker JJ. Erythroid Kruppel-like transcription factor (Eklf) maps to a region of mouse chromosome 8 syntenic with human chromosome 19. Mamm Genome 9(2):174-6, 1998. e-Pub 1998. PMID: 9457687.
Perry WL, Hustad CM, Swing DA, O'Sullivan TN, Jenkins NA, Copeland NG. The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice. Nat Genet 18(2):143-6, 1998. e-Pub 1998. PMID: 9462742.
Fernandez MP, Copeland NG, Gilbert DJ, Jenkins NA, Morgan RO. Mouse annexin III cDNA, genetic mapping and evolution. Gene 207(1):43-51, 1998. e-Pub 1998. PMID: 9511742.
Rossi DL, Hardiman G, Copeland NG, Gilbert DJ, Jenkins N, Zlotnik A, Bazan JF. Cloning and characterization of a new type of mouse chemokine. Genomics 47(2):163-70, 1998. e-Pub 1998. PMID: 9479488.
Gopalan G, Gilbert DJ, Copeland NG, Jenkins NA, Donovan PJ. Chromosome localization of two new mammalian kinases related to yeast and fly chromosome segregation-regulators. Mamm Genome 9(1):86-7, 1998. e-Pub 1998. PMID: 9434955.
Fernandez MP, Copeland NG, Gilbert DJ, Jenkins NA, Morgan RO. The genetic origin of mouse annexin VIII. Mamm Genome 9(1):8-14, 1998. e-Pub 1998. PMID: 9434938.
Fujii TA, Cvecklova K, Gilbert DJ, Copeland NG, Jenkins NA, Westphal H. Genomic structure and chromosomal localization of the murine LIM class homeobox gene Lhx1. Mamm Genome 9(1):81-3, 1998. e-Pub 1998. PMID: 9434953.
Schoenborn MA, Jenkins NA, Copeland NG, Gilbert DJ, Gayle RB 3rd, Maliszewski CR. Gene structure and chromosome location of mouse Cd39 coding for an ecto-apyrase. Cytogenet Cell Genet 81(3-4):287-9, 1998. e-Pub 1998. PMID: 9730622.
Puech A, Saint-Jore B, Funke B, Gilbert DJ, Sirotkin H, Copeland NG, Jenkins NA, Kucherlapati R, Morrow B, Skoultchi AI. Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization. Proc Natl Acad Sci U S A 94(26):14608-13, 1997. e-Pub 1997. PMID: 9405660.
Bergstein I, Eisenberg LM, Bhalerao J, Jenkins NA, Copeland NG, Osborne MP, Bowcock AM, Brown AM. Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21. Genomics 46(3):450-8, 1997. e-Pub 1997. PMID: 9441749.
Darby K, Eyre HJ, Lapsys N, Copeland NG, Gilbert DJ, Couzens M, Antonova O, Sutherland GR, Jenkins NA, Herzog H. Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14. Genomics 46(3):513-5, 1997. e-Pub 1997. PMID: 9441761.
Rausa F, Samadani U, Ye H, Lim L, Fletcher CF, Jenkins NA, Copeland NG, Costa RH. The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreas. Dev Biol 192(2):228-46, 1997. e-Pub 1997. PMID: 9441664.
Alkema MJ, Jacobs J, Voncken JW, Jenkins NA, Copeland NG, Satijn DP, Otte AP, Berns A, van Lohuizen M. MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex. J Mol Biol 273(5):993-1003, 1997. e-Pub 1997. PMID: 9367786.
Oritani K, Kanakura Y, Aoyama K, Yokota T, Copeland NG, Gilbert DJ, Jenkins NA, Tomiyama Y, Matsuzawa Y, Kincade PW. Matrix glycoprotein SC1/ECM2 augments B lymphopoiesis. Blood 90(9):3404-13, 1997. e-Pub 1997. PMID: 9345023.
Tada Y, Horio Y, Takumi T, Terayama M, Tsuji L, Copeland NG, Jenkins NA, Kurachi Y. Assignment of the glial inwardly rectifying potassium channel KAB-2/Kir4.1 (Kcnj10) gene to the distal region of mouse chromosome 1. Genomics 45(3):629-30, 1997. e-Pub 1997. PMID: 9367690.
Chen S, Wang QL, Nie Z, Sun H, Lennon G, Copeland NG, Gilbert DJ, Jenkins NA, Zack DJ. Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes. Neuron 19(5):1017-30, 1997. e-Pub 1997. PMID: 9390516.
Holz A, Frank M, Copeland NG, Gilbert DJ, Jenkins NA, Schwab ME. Chromosomal localization of the myelin-associated oligodendrocytic basic protein and expression in the genetically linked neurological mouse mutants ducky and tippy. J Neurochem 69(5):1801-9, 1997. e-Pub 1997. PMID: 9349522.
London B, Trudeau MC, Newton KP, Beyer AK, Copeland NG, Gilbert DJ, Jenkins NA, Satler CA, Robertson GA. Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current. Circ Res 81(5):870-8, 1997. e-Pub 1997. PMID: 9351462.
Jenkins NA, Woollatt E, Crawford J, Gilbert DJ, Baldwin ME, Sutherland GR, Copeland NG, Achen MG. Mapping of the gene for vascular endothelial growth factor-D in mouse and man to the X chromosome. Chromosome Res 5(7):502-5, 1997. e-Pub 1997. PMID: 9421270.
Baskaran K, Erfurth F, Taborn G, Copeland NG, Gilbert DJ, Jenkins NA, Iannaccone PM, Domer PH. Cloning and developmental expression of the murine homolog of the acute leukemia proto-oncogene AF4. Oncogene 15(16):1967-78, 1997. e-Pub 1997. PMID: 9365243.
Sladek R, Beatty B, Squire J, Copeland NG, Gilbert DJ, Jenkins NA, Giguere V. Chromosomal mapping of the human and murine orphan receptors ERRalpha (ESRRA) and ERRbeta (ESRRB) and identification of a novel human ERRalpha-related pseudogene. Genomics 45(2):320-6, 1997. e-Pub 1997. PMID: 9344655.
Fletcher CF, Okano HJ, Gilbert DJ, Yang Y, Yang C, Copeland NG, Jenkins NA, Darnell RB. Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. Genomics 45(2):313-9, 1997. e-Pub 1997. PMID: 9344654.
Hardiman G, Jenkins NA, Copeland NG, Gilbert DJ, Garcia DK, Naylor SL, Kastelein RA, Bazan JF. Genetic structure and chromosomal mapping of MyD88. Genomics 45(2):332-9, 1997. e-Pub 1997. PMID: 9344657.
Whitaker TL, Steinbrecher KA, Copeland NG, Gilbert DJ, Jenkins NA, Cohen MB. The uroguanylin gene (Guca1b) is linked to guanylin (Guca2) on mouse chromosome 4. Genomics 45(2):348-54, 1997. e-Pub 1997. PMID: 9344659.
Geusz ME, Fletcher C, Block GD, Straume M, Copeland NG, Jenkins NA, Kay SA, Day RN. Long-term monitoring of circadian rhythms in c-fos gene expression from suprachiasmatic nucleus cultures. Curr Biol 7(10):758-66, 1997. e-Pub 1997. PMID: 9368758.
Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19(4):939-45, 1997. e-Pub 1997. PMID: 9354339.
Isomoto S, Horio Y, Matsumoto S, Kondo C, Yamada M, Gilbert DJ, Copeland NG, Jenkins NA, Kurachi Y. Sur2 and Kcnj8 genes are tightly linked on the distal region of mouse chromosome 6. Mamm Genome 8(10):790-1, 1997. e-Pub 1997. PMID: 9321483.
Chang CP, Jacobs Y, Nakamura T, Jenkins NA, Copeland NG, Cleary ML. Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins. Mol Cell Biol 17(10):5679-87, 1997. e-Pub 1997. PMID: 9315626.
Colley WC, Altshuller YM, Sue-Ling CK, Copeland NG, Gilbert DJ, Jenkins NA, Branch KD, Tsirka SE, Bollag RJ, Bollag WB, Frohman MA. Cloning and expression analysis of murine phospholipase D1. Biochem J 326 ( Pt 3)(Pt 3):745-53, 1997. e-Pub 1997. PMID: 9307024.
Sun H, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium. Proc Natl Acad Sci U S A 94(18):9893-8, 1997. e-Pub 1997. PMID: 9275222.
Valk PJ, Hol S, Vankan Y, Ihle JN, Askew D, Jenkins NA, Gilbert DJ, Copeland NG, de Both NJ, Lowenberg B, Delwel R. The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11. J Virol 71(9):6796-804, 1997. e-Pub 1997. PMID: 9261404.
Mansouri A, Yokota Y, Wehr R, Copeland NG, Jenkins NA, Gruss P. Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system. Dev Dyn 210(1):53-65, 1997. e-Pub 1997. PMID: 9286595.
Jiang R, Copeland NG, Gilbert DJ, Jenkins NA, Gridley T. Genomic organization and chromosomal localization of the mouse snail (Sna) gene. Mamm Genome 8(9):686-8, 1997. e-Pub 1997. PMID: 9271672.
Morishige K, Takumi T, Takahashi N, Koyama H, Kurachi H, Miyake A, Murata Y, Copeland NG, Gilbert DJ, Jenkins NA, Kurachi Y. Assignment of the murine inwardly rectifying potassium channel IRK3 gene (Kcnj4) to the mouse chromosome 15. Mamm Genome 8(9):699-700, 1997. e-Pub 1997. PMID: 9271678.
Mishina Y, Tizard R, Deng JM, Pathak BG, Copeland NG, Jenkins NA, Cate RL, Behringer RR. Sequence, genomic organization, and chromosomal location of the mouse Mullerian-inhibiting substance type II receptor gene. Biochem Biophys Res Commun 237(3):741-6, 1997. e-Pub 1997. PMID: 9299437.
Heuckeroth RO, Kotzbauer P, Copeland NG, Gilbert DJ, Jenkins NA, Zimonjic DB, Popescu NC, Johnson EM Jr, Milbrandt J. Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3. Genomics 44(1):137-40, 1997. e-Pub 1997. PMID: 9286710.
Chang JT, Milligan S, Li Y, Chew CE, Wiggs J, Copeland NG, Jenkins NA, Campochiaro PA, Hyde DR, Zack DJ. Mammalian homolog of Drosophila retinal degeneration B rescues the mutant fly phenotype. J Neurosci 17(15):5881-90, 1997. e-Pub 1997. PMID: 9221785.
Avraham KB, Hasson T, Sobe T, Balsara B, Testa JR, Skvorak AB, Morton CC, Copeland NG, Jenkins NA. Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice. Hum Mol Genet 6(8):1225-31, 1997. e-Pub 1997. PMID: 9259267.
Vicari AP, Figueroa DJ, Hedrick JA, Foster JS, Singh KP, Menon S, Copeland NG, Gilbert DJ, Jenkins NA, Bacon KB, Zlotnik A. TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development. Immunity 7(2):291-301, 1997. e-Pub 1997. PMID: 9285413.
Sugino H, Yoshihara Y, Copeland NG, Gilbert DJ, Jenkins NA, Mori K. Genomic organization and chromosomal localization of the mouse telencephalin gene, a neuronal member of the ICAM family. Genomics 43(2):209-15, 1997. e-Pub 1997. PMID: 9244438.
Duncan MK, Kos L, Jenkins NA, Gilbert DJ, Copeland NG, Tomarev SI. Eyes absent: a gene family found in several metazoan phyla. Mamm Genome 8(7):479-85, 1997. e-Pub 1997. PMID: 9195991.
Miner JH, Patton BL, Lentz SI, Gilbert DJ, Snider WD, Jenkins NA, Copeland NG, Sanes JR. The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform. J Cell Biol 137(3):685-701, 1997. e-Pub 1997. PMID: 9151674.
Koch A, Juan TS, Jenkins NA, Gilbert DJ, Copeland NG, McNiece IK, Fletcher FA. cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T. Mamm Genome 8(5):346-8, 1997. e-Pub 1997. PMID: 9107680.
Turtzo LC, Lee MD, Lu M, Smith BL, Copeland NG, Gilbert DJ, Jenkins NA, Agre P. Cloning and chromosomal localization of mouse aquaporin 4: exclusion of a candidate mutant phenotype, ataxia. Genomics 41(2):267-70, 1997. e-Pub 1997. PMID: 9143504.
Holloway AJ, Della NG, Fletcher CF, Largespada DA, Copeland NG, Jenkins NA, Bowtell DD. Chromosomal mapping of five highly conserved murine homologues of the Drosophila RING finger gene seven-in-absentia. Genomics 41(2):160-8, 1997. e-Pub 1997. PMID: 9143490.
Rattner A, Hsieh JC, Smallwood PM, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A 94(7):2859-63, 1997. e-Pub 1997. PMID: 9096311.
Bosserhoff AK, Kondo S, Moser M, Dietz UH, Copeland NG, Gilbert DJ, Jenkins NA, Buettner R, Sandell LJ. Mouse CD-RAP/MIA gene: structure, chromosomal localization, and expression in cartilage and chondrosarcoma. Dev Dyn 208(4):516-25, 1997. e-Pub 1997. PMID: 9097023.
Kumar S, Harvey KF, Kinoshita M, Copeland NG, Noda M, Jenkins NA. cDNA cloning, expression analysis, and mapping of the mouse Nedd4 gene. Genomics 40(3):435-43, 1997. e-Pub 1997. PMID: 9073511.
Ceci JD, Patriotis CP, Tsatsanis C, Makris AM, Kovatch R, Swing DA, Jenkins NA, Tsichlis PN, Copeland NG. Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation. Genes Dev 11(6):688-700, 1997. e-Pub 1997. PMID: 9087424.
Liao X, Du Y, Morse HC 3rd, Jenkins NA, Copeland NG. Proviral integrations at the Evi5 locus disrupt a novel 90 kDa protein with homology to the Tre2 oncogene and cell-cycle regulatory proteins. Oncogene 14(9):1023-9, 1997. e-Pub 1997. PMID: 9070650.
Tamimi RM, Steingrimsson E, Montgomery-Dyer K, Copeland NG, Jenkins NA, Tapscott SJ. NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively. Genomics 40(2):355-7, 1997. e-Pub 1997. PMID: 9119405.
Tremblay GB, Tremblay A, Copeland NG, Gilbert DJ, Jenkins NA, Labrie F, Giguere V. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta. Mol Endocrinol 11(3):353-65, 1997. e-Pub 1997. PMID: 9058381.
Juan TS, McNiece IK, Argento JM, Jenkins NA, Gilbert DJ, Copeland NG, Fletcher FA. Identification and mapping of Casp7, a cysteine protease resembling CPP32 beta, interleukin-1 beta converting enzyme, and CED-3. Genomics 40(1):86-93, 1997. e-Pub 1997. PMID: 9070923.
DiLeone RJ, King JA, Storm EE, Copeland NG, Jenkins NA, Kingsley DM. The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4. Genomics 40(1):196-8, 1997. e-Pub 1997. PMID: 9070944.
Rothe H, Jenkins NA, Copeland NG, Kolb H. Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. J Clin Invest 99(3):469-74, 1997. e-Pub 1997. PMID: 9022080.
Sun XJ, Pons S, Wang LM, Zhang Y, Yenush L, Burks D, Myers MG Jr, Glasheen E, Copeland NG, Jenkins NA, Pierce JH, White MF. The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action. Mol Endocrinol 11(2):251-62, 1997. e-Pub 1997. PMID: 9013772.
Deng X, Moran J, Copeland NG, Gilbert DJ, Jenkins NA, Primakoff P, Martin-DeLeon PA. The mouse Spam1 maps to proximal chromosome 6 and is a candidate for the sperm dysfunction in Rb(6.16)24Lub and Rb(6.15)1Ald heterozygotes. Mamm Genome 8(2):94-7, 1997. e-Pub 1997. PMID: 9060406.
Zimmerman JE, Bui QT, Steingrimsson E, Nagle DL, Fu W, Genin A, Spinner NB, Copeland NG, Jenkins NA, Bucan M, Bonini NM. Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene. Genome Res 7(2):128-41, 1997. e-Pub 1997. PMID: 9049631.
Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, Sisodia SS, Rothstein JD, Borchelt DR, Price DL, Cleveland DW. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 18(2):327-38, 1997. e-Pub 1997. PMID: 9052802.
Shaughnessy JD Jr, Jenkins NA, Copeland NG. cDNA cloning, expression analysis, and chromosomal localization of a gene with high homology to wheat eIF-(iso)4F and mammalian eIF-4G. Genomics 39(2):192-7, 1997. e-Pub 1997. PMID: 9027506.
Zhu Y, Lambert K, Corless C, Copeland NG, Gilbert DJ, Jenkins NA, D'Andrea AD. DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. J Biol Chem 272(1):51-7, 1997. e-Pub 1997. PMID: 8995226.
Lyons LA, Laughlin TF, Copeland NG, Jenkins NA, Womack JE, O'Brien SJ. Comparative anchor tagged sequences (CATS) for integrative mapping of mammalian genomes. Nat Genet 15(1):47-56, 1997. e-Pub 1997. PMID: 8988168.
Belaaouaj A, Walsh BC, Jenkins NA, Copeland NG, Shapiro SD. Characterization of the mouse neutrophil elastase gene and localization to chromosome 10. Mamm Genome 8(1):5-8, 1997. e-Pub 1997. PMID: 9021140.
Leco KJ, Harvey MB, Hogan A, Copeland NG, Gilbert DJ, Jenkins NA, Edwards DR, Schultz GA. Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse. Dev Genet 21(1):55-60, 1997. e-Pub 1997. PMID: 9291580.
Guimaraes MJ, Peterson D, Vicari A, Cocks BG, Copeland NG, Gilbert DJ, Jenkins NA, Ferrick DA, Kastelein RA, Bazan JF, Zlotnik A. Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism?. Proc Natl Acad Sci U S A 93(26):15086-91, 1996. e-Pub 1996. PMID: 8986768.
George A, Bannon L, Sabsay B, Dillon JW, Malone J, Veis A, Jenkins NA, Gilbert DJ, Copeland NG. The carboxyl-terminal domain of phosphophoryn contains unique extended triplet amino acid repeat sequences forming ordered carboxyl-phosphate interaction ridges that may be essential in the biomineralization process. J Biol Chem 271(51):32869-73, 1996. e-Pub 1996. PMID: 8955126.
Miura Y, Miyake K, Yamashita Y, Shimazu R, Copeland NG, Gilbert DJ, Jenkins NA, Inazawa J, Abe T, Kimoto M. Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). Genomics 38(3):299-304, 1996. e-Pub 1996. PMID: 8975706.
Borchelt DR, Davis J, Fischer M, Lee MK, Slunt HH, Ratovitsky T, Regard J, Copeland NG, Jenkins NA, Sisodia SS, Price DL. A vector for expressing foreign genes in the brains and hearts of transgenic mice. Genet Anal 13(6):159-63, 1996. e-Pub 1996. PMID: 9117892.
Luo C, Copeland NG, Jenkins NA, Edelhoff S, Disteche C, Hogan PG, Rao A. Normal function of the transcription factor NFAT1 in wasted mice. Chromosome localization of NFAT1 gene. Gene 180(1-2):29-36, 1996. e-Pub 1996. PMID: 8973343.
Nakamura T, Jenkins NA, Copeland NG. Identification of a new family of Pbx-related homeobox genes. Oncogene 13(10):2235-42, 1996. e-Pub 1996. PMID: 8950991.
Steingrimsson E, Nii A, Fisher DE, Ferre-D'Amare AR, McCormick RJ, Russell LB, Burley SK, Ward JM, Jenkins NA, Copeland NG. The semidominant Mi(b) mutation identifies a role for the HLH domain in DNA binding in addition to its role in protein dimerization. EMBO J 15(22):6280-9, 1996. e-Pub 1996. PMID: 8947051.
Fletcher CF, Lutz CM, O'Sullivan TN, Shaughnessy JD, Hawkes R, Frankel WN, Copeland NG, Jenkins NA. Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell 87(4):607-17, 1996. e-Pub 1996. PMID: 8929530.
Quilliam LA, Lambert QT, Mickelson-Young LA, Westwick JK, Sparks AB, Kay BK, Jenkins NA, Gilbert DJ, Copeland NG, Der CJ. Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling. J Biol Chem 271(46):28772-6, 1996. e-Pub 1996. PMID: 8910519.
Grigoryev S, Stewart AE, Kwon YT, Arfin SM, Bradshaw RA, Jenkins NA, Copeland NG, Varshavsky A. A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway. J Biol Chem 271(45):28521-32, 1996. e-Pub 1996. PMID: 8910481.
Kobayashi T, Inoue I, Jenkins NA, Gilbert DJ, Copeland NG, Watanabe T. Cloning, RNA expression, and chromosomal location of a mouse histamine H2 receptor gene. Genomics 37(3):390-4, 1996. e-Pub 1996. PMID: 8938453.
Fernandez MP, Jenkins NA, Gilbert DJ, Copeland NG, Morgan RO. Sequence and chromosomal localization of mouse annexin XI. Genomics 37(3):366-74, 1996. e-Pub 1996. PMID: 8938449.
Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, Ratovitsky T, Prada CM, Kim G, Seekins S, Yager D, Slunt HH, Wang R, Seeger M, Levey AI, Gandy SE, Copeland NG, Jenkins NA, Price DL, Younkin SG, Sisodia SS. Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron 17(5):1005-13, 1996. e-Pub 1996. PMID: 8938131.
Takumi T, Tsuji L, Kondo C, Takahashi N, Morishige K, Copeland NG, Gilbert DJ, Jenkins NA, Kurachi Y. Assignment of the murine inward rectifier potassium channel Irk2 (Kir2.2) gene to the central region of mouse chromosome 11. Genomics 37(2):270-2, 1996. e-Pub 1996. PMID: 8921409.
Lock LF, Wickramasinghe D, Ernst MK, Gilbert DJ, Copeland NG, Jenkins NA, Donovan PJ. The Cdc25 genes map to mouse chromosomes 2, 9, and 18. Mamm Genome 7(10):771-2, 1996. e-Pub 1996. PMID: 8854867.
Sutton J, Costa R, Klug M, Field L, Xu D, Largaespada DA, Fletcher CF, Jenkins NA, Copeland NG, Klemsz M, Hromas R. Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells. J Biol Chem 271(38):23126-33, 1996. e-Pub 1996. PMID: 8798505.
Gale NW, Flenniken A, Compton DC, Jenkins N, Copeland NG, Gilbert DJ, Davis S, Wilkinson DG, Yancopoulos GD. Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments. Oncogene 13(6):1343-52, 1996. e-Pub 1996. PMID: 8808709.
Altshuller Y, Copeland NG, Gilbert DJ, Jenkins NA, Frohman MA. Gcm1, a mammalian homolog of Drosophila glial cells missing. FEBS Lett 393(2-3):201-4, 1996. e-Pub 1996. PMID: 8814290.
Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA. Mapping of unconventional myosins in mouse and human. Genomics 36(3):431-9, 1996. e-Pub 1996. PMID: 8884266.
Smallwood PM, Munoz-Sanjuan I, Tong P, Macke JP, Hendry SH, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci U S A 93(18):9850-7, 1996. e-Pub 1996. PMID: 8790420.
Bertuzzi S, Sheng HZ, Copeland NG, Gilbert DJ, Jenkins NA, Taira M, Dawid IB, Westphal H. Molecular cloning, structure, and chromosomal localization of the mouse LIM/homeobox gene Lhx5. Genomics 36(2):234-9, 1996. e-Pub 1996. PMID: 8812449.
Perry WL, Nakamura T, Swing DA, Secrest L, Eagleson B, Hustad CM, Copeland NG, Jenkins NA. Coupled site-directed mutagenesis/transgenesis identifies important functional domains of the mouse agouti protein. Genetics 144(1):255-64, 1996. e-Pub 1996. PMID: 8878691.
Taylor GA, Jeffers M, Largaespada DA, Jenkins NA, Copeland NG, Vande Woude GF. Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma. J Biol Chem 271(34):20399-405, 1996. e-Pub 1996. PMID: 8702776.
Juan TS, McNiece IK, Jenkins NA, Gilbert DJ, Copeland NG, Fletcher FA. Molecular characterization of mouse and rat CPP32 beta gene encoding a cysteine protease resembling interleukin-1 beta converting enzyme and CED-3. Oncogene 13(4):749-55, 1996. e-Pub 1996. PMID: 8761296.
Sun DS, Chang AC, Jenkins NA, Gilbert DJ, Copeland NG, Chang NC. Identification, molecular characterization, and chromosomal localization of the cDNA encoding a novel leucine zipper motif-containing protein. Genomics 36(1):54-62, 1996. e-Pub 1996. PMID: 8812416.
Gibson L, Holmgreen SP, Huang DC, Bernard O, Copeland NG, Jenkins NA, Sutherland GR, Baker E, Adams JM, Cory S. bcl-w, a novel member of the bcl-2 family, promotes cell survival. Oncogene 13(4):665-75, 1996. e-Pub 1996. PMID: 8761287.
Vaughan KT, Mikami A, Paschal BM, Holzbaur EL, Hughes SM, Echeverri CJ, Moore KJ, Gilbert DJ, Copeland NG, Jenkins NA, Vallee RB. Multiple mouse chromosomal loci for dynein-based motility. Genomics 36(1):29-38, 1996. e-Pub 1996. PMID: 8812413.
Inoue I, Taniuchi I, Kitamura D, Jenkins NA, Gilbert DJ, Copeland NG, Watanabe T. Characteristics of the mouse genomic histamine H1 receptor gene. Genomics 36(1):178-81, 1996. e-Pub 1996. PMID: 8812432.
Noben-Trauth K, Copeland NG, Gilbert DJ, Jenkins NA, Sonoda G, Testa JR, Klempnauer KH. Mybl2 (Bmyb) maps to mouse chromosome 2 and human chromosome 20q 13.1. Genomics 35(3):610-2, 1996. e-Pub 1996. PMID: 8812502.
Xue J, Jenkins NA, Gilbert DJ, Copeland NG, Sadler JE. Structure and localization of the thrombin receptor gene on mouse chromosome 13. Mamm Genome 7(8):625-6, 1996. e-Pub 1996. PMID: 8678993.
Liao X, Gilbert DJ, Dent A, Staudt LM, Jenkins NA, Copeland NG. Mapping of the mouse Bcl6 gene to chromosome 16. Mamm Genome 7(8):621-2, 1996. e-Pub 1996. PMID: 8678989.
Cerretti DP, Copeland NG, Gilbert DJ, Jenkins NA, Kuefer MU, Valentine V, Shapiro DN, Cui X, Morris SW. The gene encoding LERK-7 (EPLG7, Epl7), a ligand for the Eph-related receptor tyrosine kinases, maps to human chromosome 5 at band q21 and to mouse chromosome 17. Genomics 35(2):376-9, 1996. e-Pub 1996. PMID: 8661153.
Pecker I, Avraham KB, Gilbert DJ, Savitsky K, Rotman G, Harnik R, Fukao T, Schrock E, Hirotsune S, Tagle DA, Collins FS, Wynshaw-Boris A, Ried T, Copeland NG, Jenkins NA, Shiloh Y, Ziv Y. Identification and chromosomal localization of Atm, the mouse homolog of the ataxia-telangiectasia gene. Genomics 35(1):39-45, 1996. e-Pub 1996. PMID: 8661102.
Thinakaran G, Borchelt DR, Lee MK, Slunt HH, Spitzer L, Kim G, Ratovitsky T, Davenport F, Nordstedt C, Seeger M, Hardy J, Levey AI, Gandy SE, Jenkins NA, Copeland NG, Price DL, Sisodia SS. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17(1):181-90, 1996. e-Pub 1996. PMID: 8755489.
Tamimi R, Steingrimsson E, Copeland NG, Dyer-Montgomery K, Lee JE, Hernandez R, Jenkins NA, Tapscott SJ. The NEUROD gene maps to human chromosome 2q32 and mouse chromosome 2. Genomics 34(3):418-21, 1996. e-Pub 1996. PMID: 8786144.
Guimaraes MJ, Bazan JF, Castagnola J, Diaz S, Copeland NG, Gilbert DJ, Jenkins NA, Varki A, Zlotnik A. Molecular cloning and characterization of lysosomal sialic acid O-acetylesterase. J Biol Chem 271(23):13697-705, 1996. e-Pub 1996. PMID: 8662838.
Hsu DK, Guo Y, Alberts GF, Copeland NG, Gilbert DJ, Jenkins NA, Peifley KA, Winkles JA. Identification of a murine TEF-1-related gene expressed after mitogenic stimulation of quiescent fibroblasts and during myogenic differentiation. J Biol Chem 271(23):13786-95, 1996. e-Pub 1996. PMID: 8662936.
Mann EA, Swenson ES, Copeland NG, Gilbert DJ, Jenkins NA, Taguchi T, Testa JR, Giannella RA. Localization of the guanylyl cyclase C gene to mouse chromosome 6 and human chromosome 12p12. Genomics 34(2):265-7, 1996. e-Pub 1996. PMID: 8661067.
Liao X, Ma C, Trask B, Massa H, Gilbert DJ, Staudt LM, Jenkins NA, Copeland NG. LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12. Mamm Genome 7(6):467-8, 1996. e-Pub 1996. PMID: 8662235.
Marine JC, Gilbert DJ, Bellefroid EJ, Martial JA, Ihle JN, Copeland NG, Jenkins NA. Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. Mamm Genome 7(6):413-6, 1996. e-Pub 1996. PMID: 8662221.
Fan CM, Kuwana E, Bulfone A, Fletcher CF, Copeland NG, Jenkins NA, Crews S, Martinez S, Puelles L, Rubenstein LR, Tessier-Lavigne M. "Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.". Mol Cell Neurosci 7(6):519, 1996. e-Pub 1996. PMID: 8875433.
Liao X, Zhou R, Gilbert DJ, Copeland NG, Jenkins NA. Receptor tyrosine kinase gene Tyro3 maps to mouse chromosome 2, closely linked to Ltk. Mamm Genome 7(5):395-6, 1996. e-Pub 1996. PMID: 8661736.
Bell AR, Jones PS, Savory R, Barratt P, Gray TJ, Jenkins NA, Gilbert DJ, Copeland NG, Bell DR. The characterisation of expression of three murine peroxisome proliferator activated receptor genes. Biochem Soc Trans 24(2):166S, 1996. e-Pub 1996. PMID: 8736824.
Berger R, Theodor L, Shoham J, Gokkel E, Brok-Simoni F, Avraham KB, Copeland NG, Jenkins NA, Rechavi G, Simon AJ. The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products. Genome Res 6(5):361-70, 1996. e-Pub 1996. PMID: 8743987.
Moskovitz J, Jenkins NA, Gilbert DJ, Copeland NG, Jursky F, Weissbach H, Brot N. Chromosomal localization of the mammalian peptide-methionine sulfoxide reductase gene and its differential expression in various tissues. Proc Natl Acad Sci U S A 93(8):3205-8, 1996. e-Pub 1996. PMID: 8622914.
Cerretti DP, Lyman SD, Kozlosky CJ, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW. The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3. Genomics 33(2):277-82, 1996. e-Pub 1996. PMID: 8660976.
Wang J, Walker H, Lin Q, Jenkins N, Copeland NG, Watanabe T, Burrows PD, Cooper MD. The mouse BP-1 gene: structure, chromosomal localization, and regulation of expression by type I interferons and interleukin-7. Genomics 33(2):167-76, 1996. e-Pub 1996. PMID: 8660964.
Tsui CC, Copeland NG, Gilbert DJ, Jenkins NA, Barnes C, Worley PF. Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity. J Neurosci 16(8):2463-78, 1996. e-Pub 1996. PMID: 8786423.
Lee MD, Bhakta KY, Raina S, Yonescu R, Griffin CA, Copeland NG, Gilbert DJ, Jenkins NA, Preston GM, Agre P. The human Aquaporin-5 gene. Molecular characterization and chromosomal localization. J Biol Chem 271(15):8599-604, 1996. e-Pub 1996. PMID: 8621489.
Pathak BG, Shaughnessy JD Jr, Meneton P, Greeb J, Shull GE, Jenkins NA, Copeland NG. Mouse chromosomal location of three epithelial sodium channel subunit genes and an apical sodium chloride cotransporter gene. Genomics 33(1):124-7, 1996. e-Pub 1996. PMID: 8617496.
Schmitt J, Hotten G, Jenkins NA, Gilbert DJ, Copeland NG, Pohl J, Schrewe H. Structure, chromosomal localization, and expression analysis of the mouse inhibin/activin beta C (Inhbc) gene. Genomics 32(3):358-66, 1996. e-Pub 1996. PMID: 8838799.
Li X, Zimmerman A, Copeland NG, Gilbert DJ, Jenkins NA, Yin HL. The mouse thymosin beta 4 gene: structure, promoter identification, and chromosome localization. Genomics 32(3):388-94, 1996. e-Pub 1996. PMID: 8838802.
Hoeppner MA, Gilbert DJ, Copeland NG, Jenkins NA, Linzer DI, Wu B. Cloning and characterization of mouse CCAAT binding factor. Nucleic Acids Res 24(6):1091-8, 1996. e-Pub 1996. PMID: 8604343.
Yoshimura A, Ichihara M, Kinjyo I, Moriyama M, Copeland NG, Gilbert DJ, Jenkins NA, Hara T, Miyajima A. Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway. EMBO J 15(5):1055-63, 1996. e-Pub 1996. PMID: 8605875.
Bedell MA, Cleveland LS, O'Sullivan TN, Copeland NG, Jenkins NA. Deletion and interallelic complementation analysis of Steel mutant mice. Genetics 142(3):935-44, 1996. e-Pub 1996. PMID: 8849899.
Bedell MA, Jenkins NA, Copeland NG. Good genes in bad neighbourhoods. Nat Genet 12(3):229-32, 1996. e-Pub 1996. PMID: 8589709.
Bedell MA, Copeland NG, Jenkins NA. Multiple pathways for Steel regulation suggested by genomic and sequence analysis of the murine Steel gene. Genetics 142(3):927-34, 1996. e-Pub 1996. PMID: 8849898.
Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem 271(8):4468-76, 1996. e-Pub 1996. PMID: 8626800.
Nagasawa M, Sakimura K, Mori KJ, Bedell MA, Copeland NG, Jenkins NA, Mishina M. Gene structure and chromosomal localization of the mouse NMDA receptor channel subunits. Brain Res Mol Brain Res 36(1):1-11, 1996. e-Pub 1996. PMID: 9011744.
Nakamura T, Largaespada DA, Lee MP, Johnson LA, Ohyashiki K, Toyama K, Chen SJ, Willman CL, Chen IM, Feinberg AP, Jenkins NA, Copeland NG, Shaughnessy JD Jr. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet 12(2):154-8, 1996. e-Pub 1996. PMID: 8563753.
Nakamura T, Largaespada DA, Shaughnessy JD Jr, Jenkins NA, Copeland NG. Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias. Nat Genet 12(2):149-53, 1996. e-Pub 1996. PMID: 8563752.
Largaespada DA, Brannan CI, Jenkins NA, Copeland NG. Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia. Nat Genet 12(2):137-43, 1996. e-Pub 1996. PMID: 8563750.
Molnar A, Wu P, Largespada DA, Vortkamp A, Scherer S, Copeland NG, Jenkins NA, Bruns G, Georgopoulos K. The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse. J Immunol 156(2):585-92, 1996. e-Pub 1996. PMID: 8543809.
Bram RJ, Valentine V, Shapiro DN, Jenkins NA, Gilbert DJ, Copeland NG. The gene for calcium-modulating cyclophilin ligand (CAMLG) is located on human chromosome 5q23 and a syntenic region of mouse chromosome 13. Genomics 31(2):257-60, 1996. e-Pub 1996. PMID: 8824814.
Pathak BG, Shull GE, Jenkins NA, Copeland NG. Mouse chromosomal location of four Na/H exchanger isoform genes. Genomics 31(2):261-3, 1996. e-Pub 1996. PMID: 8824815.
Maemura K, Kurihara H, Kurihara Y, Oda H, Ishikawa T, Copeland NG, Gilbert DJ, Jenkins NA, Yazaki Y. Sequence analysis, chromosomal location, and developmental expression of the mouse preproendothelin-1 gene. Genomics 31(2):177-84, 1996. e-Pub 1996. PMID: 8824799.
Reynolds AB, Jenkins NA, Gilbert DJ, Copeland NG, Shapiro DN, Wu J, Daniel JM. The gene encoding p120cas, a novel catenin, localizes on human chromosome 11q11 (CTNND) and mouse chromosome 2 (Catns). Genomics 31(1):127-9, 1996. e-Pub 1996. PMID: 8808291.
Fan CM, Kuwana E, Bulfone A, Fletcher CF, Copeland NG, Jenkins NA, Crews S, Martinez S, Puelles L, Rubenstein JL, Tessier-Lavigne M. Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Mol Cell Neurosci 7(1):1-16, 1996. e-Pub 1996. PMID: 8812055.
Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA, et al.. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J Biol Chem 270(50):29862-9, 1995. e-Pub 1995. PMID: 8530383.
Santoro T, Maguire J, McBride OW, Avraham KB, Copeland NG, Jenkins NA, Kelly K. Chromosomal organization and transcriptional regulation of human GEM and localization of the human and mouse GEM loci encoding an inducible Ras-like protein. Genomics 30(3):558-64, 1995. e-Pub 1995. PMID: 8825643.
Hara T, Bacon KB, Cho LC, Yoshimura A, Morikawa Y, Copeland NG, Gilbert DJ, Jenkins NA, Schall TJ, Miyajima A. Molecular cloning and functional characterization of a novel member of the C-C chemokine family. J Immunol 155(11):5352-8, 1995. e-Pub 1995. PMID: 7594550.
Nii A, Steingrimsson E, Copeland NG, Jenkins NA, Ward JM. Mild osteopetrosis in the microphthalmia-oak ridge mouse. A model for intermediate autosomal recessive osteopetrosis in humans. Am J Pathol 147(6):1871-82, 1995. e-Pub 1995. PMID: 7495310.
Oliver G, Mailhos A, Wehr R, Copeland NG, Jenkins NA, Gruss P. Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 121(12):4045-55, 1995. e-Pub 1995. PMID: 8575305.
Avraham KB, Hasson T, Steel KP, Kingsley DM, Russell LB, Mooseker MS, Copeland NG, Jenkins NA. The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nat Genet 11(4):369-75, 1995. e-Pub 1995. PMID: 7493015.
Moon C, Williams JB, Preston GM, Copeland NG, Gilbert DJ, Nathans D, Jenkins NA, Agre P. The mouse aquaporin-1 gene. Genomics 30(2):354-7, 1995. e-Pub 1995. PMID: 8586439.
Hurlin PJ, Queva C, Koskinen PJ, Steingrimsson E, Ayer DE, Copeland NG, Jenkins NA, Eisenman RN. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J 14(22):5646-59, 1995. e-Pub 1995. PMID: 8521822.
Lee CH, Copeland NG, Gilbert DJ, Jenkins NA, Wei LN. Genomic structure, promoter identification, and chromosomal mapping of a mouse nuclear orphan receptor expressed in embryos and adult testes. Genomics 30(1):46-52, 1995. e-Pub 1995. PMID: 8595902.
Liao X, Buchberg AM, Jenkins NA, Copeland NG. Evi-5, a common site of retroviral integration in AKXD T-cell lymphomas, maps near Gfi-1 on mouse chromosome 5. J Virol 69(11):7132-7, 1995. e-Pub 1995. PMID: 7474133.
Cho BC, Shaughnessy JD Jr, Largaespada DA, Bedigian HG, Buchberg AM, Jenkins NA, Copeland NG. Frequent disruption of the Nf1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas. J Virol 69(11):7138-46, 1995. e-Pub 1995. PMID: 7474134.
Cerretti DP, Vanden Bos T, Nelson N, Kozlosky CJ, Reddy P, Maraskovsky E, Park LS, Lyman SD, Copeland NG, Gilbert DJ, et al.. Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases. Mol Immunol 32(16):1197-205, 1995. e-Pub 1995. PMID: 8559144.
Rosenbaum T, Boissy YL, Kombrinck K, Brannan CI, Jenkins NA, Copeland NG, Ratner N. Neurofibromin-deficient fibroblasts fail to form perineurium in vitro. Development 121(11):3583-92, 1995. e-Pub 1995. PMID: 8582272.
von Koch CS, Lahiri DK, Mammen AL, Copeland NG, Gilbert DJ, Jenkins NA, Sisodia S. The mouse APLP2 gene. Chromosomal localization and promoter characterization. J Biol Chem 270(43):25475-80, 1995. e-Pub 1995. PMID: 7592716.
Gersten KM, Natsuka S, Trinchera M, Petryniak B, Kelly RJ, Hiraiwa N, Jenkins NA, Gilbert DJ, Copeland NG, Lowe JB. Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase. J Biol Chem 270(42):25047-56, 1995. e-Pub 1995. PMID: 7559635.
Hulsebos TJ, Gilbert DJ, Delattre O, Smink LJ, Dunham I, Westerveld A, Thomas G, Jenkins NA, Copeland NG. Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5. Genomics 29(3):712-8, 1995. e-Pub 1995. PMID: 8575764.
Jones PS, Savory R, Barratt P, Bell AR, Gray TJ, Jenkins NA, Gilbert DJ, Copeland NG, Bell DR. Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome-proliferator-activated-receptor genes. Eur J Biochem 233(1):219-26, 1995. e-Pub 1995. PMID: 7588749.
Vogel KS, Brannan CI, Jenkins NA, Copeland NG, Parada LF. Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons. Cell 82(5):733-42, 1995. e-Pub 1995. PMID: 7671302.
Copeland NG, Gilbert DJ, Schindler C, Zhong Z, Wen Z, Darnell JE Jr, Mui AL, Miyajima A, Quelle FW, Ihle JN, et al.. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics 29(1):225-8, 1995. e-Pub 1995. PMID: 8530075.
Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson L, Yang-Feng T, Jenkins NA, Tsai MJ, Tsai SY. Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes. Genomics 29(1):240-6, 1995. e-Pub 1995. PMID: 8530078.
Youn BS, Jang IK, Broxmeyer HE, Cooper S, Jenkins NA, Gilbert DJ, Copeland NG, Elick TA, Fraser MJ Jr, Kwon BS. A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors. J Immunol 155(5):2661-7, 1995. e-Pub 1995. PMID: 7650394.
Marker PC, King JA, Copeland NG, Jenkins NA, Kingsley DM. Chromosomal localization, embryonic expression, and imprinting tests for Bmp7 on distal mouse chromosome 2. Genomics 28(3):576-80, 1995. e-Pub 1995. PMID: 7490098.
Giguere V, Beatty B, Squire J, Copeland NG, Jenkins NA. The orphan nuclear receptor ROR alpha (RORA) maps to a conserved region of homology on human chromosome 15q21-q22 and mouse chromosome 9. Genomics 28(3):596-8, 1995. e-Pub 1995. PMID: 7490103.
Hulsebos TJ, Cerosaletti KM, Fournier RE, Sinke RJ, Rocchi M, Marzella R, Jenkins NA, Gilbert DJ, Copeland NG. Identification of the human beta A2 crystallin gene (CRYBA2): localization of the gene on human chromosome 2 and of the homologous gene on mouse chromosome 1. Genomics 28(3):543-8, 1995. e-Pub 1995. PMID: 7490092.
Largaespada DA, Shaughnessy JD Jr, Jenkins NA, Copeland NG. Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels. J Virol 69(8):5095-102, 1995. e-Pub 1995. PMID: 7609078.
Cross JC, Flannery ML, Blanar MA, Steingrimsson E, Jenkins NA, Copeland NG, Rutter WJ, Werb Z. Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development. Development 121(8):2513-23, 1995. e-Pub 1995. PMID: 7671815.
Ai Y, Jenkins NA, Copeland NG, Gilbert DH, Bergsma DJ, Stambolian D. Mouse galactokinase: isolation, characterization, and location on chromosome 11. Genome Res 5(1):53-9, 1995. e-Pub 1995. PMID: 8717055.
Ellis J, Liu Q, Breitman M, Jenkins NA, Gilbert DJ, Copeland NG, Tempest HV, Warren S, Muir E, Schilling H, et al.. Embryo brain kinase: a novel gene of the eph/elk receptor tyrosine kinase family. Mech Dev 52(2-3):319-41, 1995. e-Pub 1995. PMID: 8541219.
Chen XS, Naumann TA, Kurre U, Jenkins NA, Copeland NG, Funk CD. cDNA cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase. J Biol Chem 270(30):17993-9, 1995. e-Pub 1995. PMID: 7629107.
Jenkins NA, Gilbert DJ, Cho BC, Strobel MC, Williams SC, Copeland NG, Johnson PF. Mouse chromosomal location of the CCAAT/enhancer binding proteins C/EBP beta (Cebpb), C/EBP delta (Cebpd), and CRP1 (Cebpe). Genomics 28(2):333-6, 1995. e-Pub 1995. PMID: 8530045.
Li L, Chin LS, Greengard P, Copeland NG, Gilbert DJ, Jenkins NA. Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6. Genomics 28(2):365-6, 1995. e-Pub 1995. PMID: 8530057.
Jenkins NA, Gilbert DJ, Yamamoto R, Kilimann MW, Copeland NG. Amphiphysin (Amph) maps to the proximal region of mouse chromosome 13. Genomics 28(2):363-5, 1995. e-Pub 1995. PMID: 8530056.
Steingrimsson E, Sawadogo M, Gilbert DJ, Zervos AS, Brent R, Blanar MA, Fisher DE, Copeland NG, Jenkins NA. Murine chromosomal location of five bHLH-Zip transcription factor genes. Genomics 28(2):179-83, 1995. e-Pub 1995. PMID: 8530024.
Pathak BG, Gilbert DJ, Harrison CA, Luetteke NC, Chen X, Klagsbrun M, Plowman GD, Copeland NG, Jenkins NA, Lee DC. Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl). Genomics 28(1):116-8, 1995. e-Pub 1995. PMID: 7590736.
Marigo V, Roberts DJ, Lee SM, Tsukurov O, Levi T, Gastier JM, Epstein DJ, Gilbert DJ, Copeland NG, Seidman CE, et al.. Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog. Genomics 28(1):44-51, 1995. e-Pub 1995. PMID: 7590746.
Blanar MA, Crossley PH, Peters KG, Steingrimsson E, Copeland NG, Jenkins NA, Martin GR, Rutter WJ. Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development. Proc Natl Acad Sci U S A 92(13):5870-4, 1995. e-Pub 1995. PMID: 7597044.
Yoshimura A, Ohkubo T, Kiguchi T, Jenkins NA, Gilbert DJ, Copeland NG, Hara T, Miyajima A. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J 14(12):2816-26, 1995. e-Pub 1995. PMID: 7796808.
Chen H, Thalmann I, Adams JC, Avraham KB, Copeland NG, Jenkins NA, Beier DR, Corey DP, Thalmann R, Duyk GM. cDNA cloning, tissue distribution, and chromosomal localization of Ocp2, a gene encoding a putative transcription-associated factor predominantly expressed in the auditory organs. Genomics 27(3):389-98, 1995. e-Pub 1995. PMID: 7558018.
Bozza M, Kolakowski LF Jr, Jenkins NA, Gilbert DJ, Copeland NG, David JR, Gerard C. Structural characterization and chromosomal location of the mouse macrophage migration inhibitory factor gene and pseudogenes. Genomics 27(3):412-9, 1995. e-Pub 1995. PMID: 7558021.
Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14(6):1105-16, 1995. e-Pub 1995. PMID: 7605627.
Seperack PK, Mercer JA, Strobel MC, Copeland NG, Jenkins NA. Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner. EMBO J 14(10):2326-32, 1995. e-Pub 1995. PMID: 7774591.
Zhadanov AB, Copeland NG, Gilbert DJ, Jenkins NA, Westphal H. Genomic structure and chromosomal localization of the mouse LIM/homeobox gene Lhx3. Genomics 27(1):27-32, 1995. e-Pub 1995. PMID: 7665181.
Hustad CM, Perry WL, Siracusa LD, Rasberry C, Cobb L, Cattanach BM, Kovatch R, Copeland NG, Jenkins NA. Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus. Genetics 140(1):255-65, 1995. e-Pub 1995. PMID: 7635290.
Wei LN, Lee CH, Chinpaisal C, Copeland NG, Gilbert DJ, Jenkins NA, Hsu YC. Studies of cloning, chromosomal mapping, and embryonic expression of the mouse Rab geranylgeranyl transferase beta subunit. Cell Growth Differ 6(5):607-14, 1995. e-Pub 1995. PMID: 7544156.
Perry WL, Hustad CM, Swing DA, Jenkins NA, Copeland NG. A transgenic mouse assay for agouti protein activity. Genetics 140(1):267-74, 1995. e-Pub 1995. PMID: 7635291.
Tsuji K, Copeland NG, Jenkins NA, Obinata M. Mammalian antioxidant protein complements alkylhydroperoxide reductase (ahpC) mutation in Escherichia coli. Biochem J 307 ( Pt 2)(Pt 2):377-81, 1995. e-Pub 1995. PMID: 7733872.
Chang MS, Hsu RY, McNinch J, Copeland NG, Jenkins NA. The gene for murine megakaryocyte growth and development factor (thrombopoietin, Thpo) is located on mouse chromosome 16. Genomics 26(3):636-7, 1995. e-Pub 1995. PMID: 7607698.
Cserjesi P, Brown D, Ligon KL, Lyons GE, Copeland NG, Gilbert DJ, Jenkins NA, Olson EN. Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Development 121(4):1099-110, 1995. e-Pub 1995. PMID: 7743923.
Birkeland ML, Copeland NG, Gilbert DJ, Jenkins NA, Barclay AN. Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein. Eur J Immunol 25(4):926-30, 1995. e-Pub 1995. PMID: 7737295.
Sciaky D, Jenkins NA, Gilbert DJ, Copeland NG, Sonoda G, Testa JR, Cohen MB. Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35. Genomics 26(2):427-9, 1995. e-Pub 1995. PMID: 7601480.
Amadou C, Ribouchon MT, Mattei MG, Jenkins NA, Gilbert DJ, Copeland NG, Avoustin P, Pontarotti P. Localization of new genes and markers to the distal part of the human major histocompatibility complex (MHC) region and comparison with the mouse: new insights into the evolution of mammalian genomes. Genomics 26(1):9-20, 1995. e-Pub 1995. PMID: 7782091.
Miyajima I, Levitt L, Hara T, Bedell MA, Copeland NG, Jenkins NA, Miyajima A. The murine interleukin-3 receptor alpha subunit gene: chromosomal localization, genomic structure, and promoter function. Blood 85(5):1246-53, 1995. e-Pub 1995. PMID: 7858255.
Oliver G, Wehr R, Jenkins NA, Copeland NG, Cheyette BN, Hartenstein V, Zipursky SL, Gruss P. Homeobox genes and connective tissue patterning. Development 121(3):693-705, 1995. e-Pub 1995. PMID: 7720577.
Guillemot F, Caspary T, Tilghman SM, Copeland NG, Gilbert DJ, Jenkins NA, Anderson DJ, Joyner AL, Rossant J, Nagy A. Genomic imprinting of Mash2, a mouse gene required for trophoblast development. Nat Genet 9(3):235-42, 1995. e-Pub 1995. PMID: 7773285.
Siracusa LD, Washburn LL, Swing DA, Argeson AC, Jenkins NA, Copeland NG. Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles. J Hered 86(2):121-8, 1995. e-Pub 1995. PMID: 7751596.
Bedell MA, Brannan CI, Evans EP, Copeland NG, Jenkins NA, Donovan PJ. DNA rearrangements located over 100 kb 5' of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development. Genes Dev 9(4):455-70, 1995. e-Pub 1995. PMID: 7533739.
Anderson DM, Johnson L, Glaccum MB, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW, et al.. Chromosomal assignment and genomic structure of Il15. Genomics 25(3):701-6, 1995. e-Pub 1995. PMID: 7759105.
Allikmets R, Gerrard B, Glavac D, Ravnik-Glavac M, Jenkins NA, Gilbert DJ, Copeland NG, Modi W, Dean M. Characterization and mapping of three new mammalian ATP-binding transporter genes from an EST database. Mamm Genome 6(2):114-7, 1995. e-Pub 1995. PMID: 7766993.
Lyford GL, Yamagata K, Kaufmann WE, Barnes CA, Sanders LK, Copeland NG, Gilbert DJ, Jenkins NA, Lanahan AA, Worley PF. Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. Neuron 14(2):433-45, 1995. e-Pub 1995. PMID: 7857651.
Avraham KB, Fletcher C, Overdier DG, Clevidence DE, Lai E, Costa RH, Jenkins NA, Copeland NG. Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors. Genomics 25(2):388-93, 1995. e-Pub 1995. PMID: 7789972.
Hulsebos TJ, Jenkins NA, Gilbert DJ, Copeland NG. The beta crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5. Genomics 25(2):574-6, 1995. e-Pub 1995. PMID: 7789995.
Avraham KB, Levanon D, Negreanu V, Bernstein Y, Groner Y, Copeland NG, Jenkins NA. Mapping of the mouse homolog of the human runt domain gene, AML2, to the distal region of mouse chromosome 4. Genomics 25(2):603-5, 1995. e-Pub 1995. PMID: 7790005.
Lyman SD, James L, Escobar S, Downey H, de Vries P, Brasel K, Stocking K, Beckmann MP, Copeland NG, Cleveland LS, et al.. Identification of soluble and membrane-bound isoforms of the murine flt3 ligand generated by alternative splicing of mRNAs. Oncogene 10(1):149-57, 1995. e-Pub 1995. PMID: 7824267.
Mishina Y, Suzuki A, Gilbert DJ, Copeland NG, Jenkins NA, Ueno N, Behringer RR. Genomic organization and chromosomal location of the mouse type I BMP-2/4 receptor. Biochem Biophys Res Commun 206(1):310-7, 1995. e-Pub 1995. PMID: 7818535.
Valenzuela DM, Rojas E, Le Beau MM, Espinosa R 3rd, Brannan CI, McClain J, Masiakowski P, Ip NY, Copeland NG, Jenkins NA, et al.. Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor. Genomics 25(1):157-63, 1995. e-Pub 1995. PMID: 7774913.
Thia KY, Jenkins NA, Gilbert DJ, Copeland NG, Smyth MJ. The natural killer cell serine protease gene Lmet1 maps to mouse chromosome 10. Immunogenetics 41(1):47-9, 1995. e-Pub 1995. PMID: 7806275.
O'Hara B, Jenkins NA, Gilbert DJ, Copeland NG, Shows TB, Eddy RL, Bohlen P, Kovesdi I. Chromosomal assignment of the heparin-binding cytokine genes MDK and PTN in mouse and man. Cytogenet Cell Genet 69(1-2):40-3, 1995. e-Pub 1995. PMID: 7835084.
Cunningham NS, Jenkins NA, Gilbert DJ, Copeland NG, Reddi AH, Lee SJ. Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3. Growth Factors 12(2):99-109, 1995. e-Pub 1995. PMID: 8679252.
Habets GG, van der Kammen RA, Jenkins NA, Gilbert DJ, Copeland NG, Hagemeijer A, Collard JG. The invasion-inducing TIAM1 gene maps to human chromosome band 21q22 and mouse chromosome 16. Cytogenet Cell Genet 70(1-2):48-51, 1995. e-Pub 1995. PMID: 7736788.
Moore KJ, Testa JR, Francke U, Milatovich A, Copeland NG, Jenkins NA. Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21. Cytogenet Cell Genet 69(1-2):53-8, 1995. e-Pub 1995. PMID: 7835087.
Bell DW, Taguchi T, Jenkins NA, Gilbert DJ, Copeland NG, Gilks CB, Zweidler-McKay P, Grimes HL, Tsichlis PN, Testa JR. Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents. Cytogenet Cell Genet 70(3-4):263-7, 1995. e-Pub 1995. PMID: 7789186.
Mathew P, Morris SW, Kane JR, Shurtleff SA, Pasquini M, Jenkins NA, Gilbert DJ, Copeland NG. Localization of the murine homolog of the anaplastic lymphoma kinase (AlK) gene on mouse chromosome 17. Cytogenet Cell Genet 70(1-2):143-4, 1995. e-Pub 1995. PMID: 7736780.
Lee CG, Jenkins NA, Gilbert DJ, Copeland NG, O'Brien WE. Cloning and analysis of gene regulation of a novel LPS-inducible cDNA. Immunogenetics 41(5):263-70, 1995. e-Pub 1995. PMID: 7721348.
Trauth K, Mutschler B, Jenkins NA, Gilbert DJ, Copeland NG, Klempnauer KH. Mouse A-myb encodes a trans-activator and is expressed in mitotically active cells of the developing central nervous system, adult testis and B lymphocytes. EMBO J 13(24):5994-6005, 1994. e-Pub 1994. PMID: 7813437.
Szpirer C, Molne M, Antonacci R, Jenkins NA, Finelli P, Szpirer J, Riviere M, Rocchi M, Gilbert DJ, Copeland NG, et al.. The genes encoding the glutamate receptor subunits KA1 and KA2 (GRIK4 and GRIK5) are located on separate chromosomes in human, mouse, and rat. Proc Natl Acad Sci U S A 91(25):11849-53, 1994. e-Pub 1994. PMID: 7527545.
Himmelbauer H, Harvey RP, Copeland NG, Jenkins NA, Silver LM. High-resolution genetic analysis of a deletion on mouse chromosome 17 extending over the fused, tufted, and homeobox Nkx2-5 loci. Mamm Genome 5(12):814-6, 1994. e-Pub 1994. PMID: 7894168.
Newton G, Weremowicz S, Morton CC, Copeland NG, Gilbert DJ, Jenkins NA, Lawler J. Characterization of human and mouse cartilage oligomeric matrix protein. Genomics 24(3):435-9, 1994. e-Pub 1994. PMID: 7713493.
Ishikawa H, Silos SA, Tamai K, Copeland NG, Gilbert DJ, Jenkins NA, Uitto J. cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen. Mamm Genome 5(12):803-4, 1994. e-Pub 1994. PMID: 7894164.
Yamin M, Gorn AH, Flannery MR, Jenkins NA, Gilbert DJ, Copeland NG, Tapp DR, Krane SM, Goldring SR. Cloning and characterization of a mouse brain calcitonin receptor complementary deoxyribonucleic acid and mapping of the calcitonin receptor gene. Endocrinology 135(6):2635-43, 1994. e-Pub 1994. PMID: 7988453.
George A, Gui J, Jenkins NA, Gilbert DJ, Copeland NG, Veis A. In situ localization and chromosomal mapping of the AG1 (Dmp1) gene. J Histochem Cytochem 42(12):1527-31, 1994. e-Pub 1994. PMID: 7983353.
Kelner GS, Kennedy J, Bacon KB, Kleyensteuber S, Largaespada DA, Jenkins NA, Copeland NG, Bazan JF, Moore KW, Schall TJ, et al.. Lymphotactin: a cytokine that represents a new class of chemokine. Science 266(5189):1395-9, 1994. e-Pub 1994. PMID: 7973732.
Kirschner MA, Copeland NG, Gilbert DJ, Jenkins NA, Amara SG. Mouse excitatory amino acid transporter EAAT2: isolation, characterization, and proximity to neuroexcitability loci on mouse chromosome 2. Genomics 24(2):218-24, 1994. e-Pub 1994. PMID: 7698742.
Gautam M, Mudd J, Copeland NG, Gilbert DJ, Jenkins NA, Merlie JP. Characterization and mapping of the Rapsn gene encoding the 43-kDa acetylcholine receptor-associated protein. Genomics 24(2):366-9, 1994. e-Pub 1994. PMID: 7698761.
Hemesath TJ, Steingrimsson E, McGill G, Hansen MJ, Vaught J, Hodgkinson CA, Arnheiter H, Copeland NG, Jenkins NA, Fisher DE. microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. Genes Dev 8(22):2770-80, 1994. e-Pub 1994. PMID: 7958932.
Miao GG, Smeyne RJ, D'Arcangelo G, Copeland NG, Jenkins NA, Morgan JI, Curran T. Isolation of an allele of reeler by insertional mutagenesis. Proc Natl Acad Sci U S A 91(23):11050-4, 1994. e-Pub 1994. PMID: 7972007.
Fletcher FA, Renshaw B, Hollingsworth T, Baum P, Lyman SD, Jenkins NA, Gilbert DJ, Copeland NG, Davison BL. Genomic organization and chromosomal localization of mouse Eplg2, a gene encoding a binding protein for the receptor tyrosine kinase elk. Genomics 24(1):127-32, 1994. e-Pub 1994. PMID: 7896266.
Terajima M, Matsui Y, Copeland NG, Gilbert DJ, Jenkins NA, Obinata M. Structural organization of the mouse glycophorin A gene. J Biochem 116(5):1105-10, 1994. e-Pub 1994. PMID: 7896738.
Lee CG, Gilbert DJ, O'Brien WE, Jenkins NA, Copeland NG. Localization of a novel, LPS-inducible member of the thymidylate kinase family to mouse chromosome 12. Mamm Genome 5(11):742-3, 1994. e-Pub 1994. PMID: 7873892.
Steingrimsson E, Moore KJ, Lamoreux ML, Ferre-D'Amare AR, Burley SK, Zimring DC, Skow LC, Hodgkinson CA, Arnheiter H, Copeland NG, et al.. Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences. Nat Genet 8(3):256-63, 1994. e-Pub 1994. PMID: 7874168.
Kavety B, Jenkins NA, Fletcher CF, Copeland NG, Morgan JI. Genomic structure and mapping of precerebellin and a precerebellin-related gene. Brain Res Mol Brain Res 27(1):152-6, 1994. e-Pub 1994. PMID: 7877445.
Moore KJ, Swing DA, Copeland NG, Jenkins NA. The murine dilute suppressor gene encodes a cell autonomous suppressor. Genetics 138(2):491-7, 1994. e-Pub 1994. PMID: 7828830.
Ashar HR, Benson KF, Jenkins NA, Gilbert DJ, Copeland NG, Chada KK. Ifg, Gli, Mdm1, Mdm2, and Mdm3: candidate genes for the mouse pg locus. Mamm Genome 5(10):608-11, 1994. e-Pub 1994. PMID: 7849395.
Rothnagel JA, Longley MA, Bundman DS, Naylor SL, Lalley PA, Jenkins NA, Gilbert DJ, Copeland NG, Roop DR. Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3. Genomics 23(2):450-6, 1994. e-Pub 1994. PMID: 7835895.
Kirschner MA, Arriza JL, Copeland NG, Gilbert DJ, Jenkins NA, Magenis E, Amara SG. The mouse and human excitatory amino acid transporter gene (EAAT1) maps to mouse chromosome 15 and a region of syntenic homology on human chromosome 5. Genomics 22(3):631-3, 1994. e-Pub 1994. PMID: 8001975.
Copeland NG, Jenkins NA, Harvey RP. The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively. Genomics 22(3):655-6, 1994. e-Pub 1994. PMID: 8001981.
Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. Genes Dev 8(14):1613-26, 1994. e-Pub 1994. PMID: 7958843.
Yamamoto K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, Jenkins NA, Copeland NG, Silvennoinen O, Ihle JN. Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol 14(7):4342-9, 1994. e-Pub 1994. PMID: 8007943.
Buxton RS, Wheeler GN, Pidsley SC, Marsden MD, Adams MJ, Jenkins NA, Gilbert DJ, Copeland NG. Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18. Genomics 21(3):510-6, 1994. e-Pub 1994. PMID: 7959727.
Spring J, Goldberger OA, Jenkins NA, Gilbert DJ, Copeland NG, Bernfield M. Mapping of the syndecan genes in the mouse: linkage with members of the myc gene family. Genomics 21(3):597-601, 1994. e-Pub 1994. PMID: 7959737.
Kou K, James PL, Clemmons DR, Copeland NG, Gilbert DJ, Jenkins NA, Rotwein P. Identification of two clusters of mouse insulin-like growth factor binding protein genes on chromosomes 1 and 11. Genomics 21(3):653-5, 1994. e-Pub 1994. PMID: 7525452.
Avraham KB, Givol D, Avivi A, Yayon A, Copeland NG, Jenkins NA. Mapping of murine fibroblast growth factor receptors refines regions of homology between mouse and human chromosomes. Genomics 21(3):656-8, 1994. e-Pub 1994. PMID: 7959747.
Chen XS, Kurre U, Jenkins NA, Copeland NG, Funk CD. cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases. J Biol Chem 269(19):13979-87, 1994. e-Pub 1994. PMID: 8188678.
Mallo M, Steingrimsson E, Copeland NG, Jenkins NA, Gridley T. Genomic organization, alternative polyadenylation, and chromosomal localization of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex. Genomics 21(1):194-201, 1994. e-Pub 1994. PMID: 7916324.
Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, Buchberg AM, Jenkins NA, Parada LF, Copeland NG. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev 8(9):1019-29, 1994. e-Pub 1994. PMID: 7926784.
Hess EJ, Collins KA, Copeland NG, Jenkins NA, Wilson MC. Deletion map of the coloboma (Cm) locus on mouse chromosome 2. Genomics 21(1):257-61, 1994. e-Pub 1994. PMID: 7916325.
Salinas PC, Fletcher C, Copeland NG, Jenkins NA, Nusse R. Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells. Development 120(5):1277-86, 1994. e-Pub 1994. PMID: 8026336.
Bae SC, Ogawa E, Maruyama M, Oka H, Satake M, Shigesada K, Jenkins NA, Gilbert DJ, Copeland NG, Ito Y. PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials. Mol Cell Biol 14(5):3242-52, 1994. e-Pub 1994. PMID: 8164679.
Muglia LJ, Jenkins NA, Gilbert DJ, Copeland NG, Majzoub JA. Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells. J Clin Invest 93(5):2066-72, 1994. e-Pub 1994. PMID: 8182138.
Uchida N, Shimamura K, Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M. Mouse alpha N-catenin: two isoforms, specific expression in the nervous system, and chromosomal localization of the gene. Dev Biol 163(1):75-85, 1994. e-Pub 1994. PMID: 8174789.
Swendeman SL, Spielholz C, Jenkins NA, Gilbert DJ, Copeland NG, Sheffery M. Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2. J Biol Chem 269(15):11663-71, 1994. e-Pub 1994. PMID: 8157699.
Storm EE, Huynh TV, Copeland NG, Jenkins NA, Kingsley DM, Lee SJ. Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily. Nature 368(6472):639-43, 1994. e-Pub 1994. PMID: 8145850.
Kou K, Jenkins NA, Gilbert DJ, Copeland NG, Rotwein P. Organization, expression, and chromosomal location of the mouse insulin-like growth factor binding protein 5 gene. Genomics 20(3):412-8, 1994. e-Pub 1994. PMID: 7518410.
Clegg CH, Koeiman NR, Jenkins NA, Gilbert DJ, Copeland NG, Neubauer MG. Structural features of the murine gene encoding the RI beta subunit of cAMP-dependent protein kinase. Mol Cell Neurosci 5(2):153-64, 1994. e-Pub 1994. PMID: 8032683.
Lock LF, Gilbert DJ, Street VA, Migeon MB, Jenkins NA, Copeland NG, Tempel BL. Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome. Genomics 20(3):354-62, 1994. e-Pub 1994. PMID: 8034307.
Bellacosa A, Datta K, Bear SE, Patriotis C, Lazo PA, Copeland NG, Jenkins NA, Tsichlis PN. Effects of provirus integration in the Tpl-1/Ets-1 locus in Moloney murine leukemia virus-induced rat T-cell lymphomas: levels of expression, polyadenylation, transcriptional initiation, and differential splicing of the Ets-1 mRNA. J Virol 68(4):2320-30, 1994. e-Pub 1994. PMID: 8139017.
Hamel CP, Jenkins NA, Gilbert DJ, Copeland NG, Redmond TM. The gene for the retinal pigment epithelium-specific protein RPE65 is localized to human 1p31 and mouse 3. Genomics 20(3):509-12, 1994. e-Pub 1994. PMID: 8034329.
Brown A, Copeland NG, Gilbert DJ, Jenkins NA, Rossant J, Kothary R. The genomic structure of an insertional mutation in the dystonia musculorum locus. Genomics 20(3):371-6, 1994. e-Pub 1994. PMID: 8034309.
Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76(6):969-76, 1994. e-Pub 1994. PMID: 7511063.
Ito Y, Seto Y, Brannan CI, Copeland NG, Jenkins NA, Fukunaga R, Nagata S. Structural analysis of the functional gene and pseudogene encoding the murine granulocyte colony-stimulating-factor receptor. Eur J Biochem 220(3):881-91, 1994. e-Pub 1994. PMID: 8143742.
Wymore RS, Korenberg JR, Kinoshita KD, Aiyar J, Coyne C, Chen XN, Hustad CM, Copeland NG, Gutman GA, Jenkins NA, et al.. Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13. Genomics 20(2):191-202, 1994. e-Pub 1994. PMID: 8020965.
Martin JF, Miano JM, Hustad CM, Copeland NG, Jenkins NA, Olson EN. A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing. Mol Cell Biol 14(3):1647-56, 1994. e-Pub 1994. PMID: 8114702.
Justice MJ, Morse HC 3rd, Jenkins NA, Copeland NG. Identification of Evi-3, a novel common site of retroviral integration in mouse AKXD B-cell lymphomas. J Virol 68(3):1293-300, 1994. e-Pub 1994. PMID: 8107195.
Luetteke NC, Phillips HK, Qiu TH, Copeland NG, Earp HS, Jenkins NA, Lee DC. The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev 8(4):399-413, 1994. e-Pub 1994. PMID: 8125255.
Chang NC, Jenkins NA, Gilbert DJ, Copeland NG, Chang YH, Chen WM, Chang AC. Assignment of two alpha 2 adrenoceptor subtype genes to murine chromosomes. Neurosci Lett 167(1-2):105-8, 1994. e-Pub 1994. PMID: 8177505.
DeGregori J, Russ A, von Melchner H, Rayburn H, Priyaranjan P, Jenkins NA, Copeland NG, Ruley HE. A murine homolog of the yeast RNA1 gene is required for postimplantation development. Genes Dev 8(3):265-76, 1994. e-Pub 1994. PMID: 8314081.
Ziegler SF, Levin SD, Johnson L, Copeland NG, Gilbert DJ, Jenkins NA, Baker E, Sutherland GR, Feldhaus AL, Ramsdell F. The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex. J Immunol 152(3):1228-36, 1994. e-Pub 1994. PMID: 8301128.
Edelhoff S, Ayer DE, Zervos AS, Steingrimsson E, Jenkins NA, Copeland NG, Eisenman RN, Brent R, Disteche CM. Mapping of two genes encoding members of a distinct subfamily of MAX interacting proteins: MAD to human chromosome 2 and mouse chromosome 6, and MXI1 to human chromosome 10 and mouse chromosome 19. Oncogene 9(2):665-8, 1994. e-Pub 1994. PMID: 8290278.
Ceci JD, Matsuda Y, Grubber JM, Jenkins NA, Copeland NG, Chapman VM. Interspecific backcrosses provide an important new tool for centromere mapping of mouse chromosomes. Genomics 19(3):515-24, 1994. e-Pub 1994. PMID: 8188294.
Jenkins NA, Rothe H, Gilbert DJ, Copeland NG, Kolb H. Mapping of the gene for inducible nitric oxide (NO) synthase of mouse macrophages to chromosome 11, close to Evi-2, nu, and Idd-4. Genomics 19(2):402-4, 1994. e-Pub 1994. PMID: 7514570.
Perez JL, Shen X, Finkernagel S, Sciorra L, Jenkins NA, Gilbert DJ, Copeland NG, Wong TW. Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain. Oncogene 9(1):211-9, 1994. e-Pub 1994. PMID: 8302582.
Morishige K, Takahashi N, Findlay I, Koyama H, Zanelli JS, Peterson C, Jenkins NA, Copeland NG, Mori N, Kurachi Y. Molecular cloning, functional expression and localization of an inward rectifier potassium channel in the mouse brain. FEBS Lett 336(3):375-80, 1993. e-Pub 1993. PMID: 8282096.
MacNeil I, Kennedy J, Godfrey DI, Jenkins NA, Masciantonio M, Mineo C, Gilbert DJ, Copeland NG, Boyd RL, Zlotnik A. Isolation of a cDNA encoding thymic shared antigen-1. A new member of the Ly6 family with a possible role in T cell development. J Immunol 151(12):6913-23, 1993. e-Pub 1993. PMID: 8258699.
Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75(5):1027-38, 1993. e-Pub 1993. PMID: 8252616.
Ahouse JJ, Hagerman CL, Mittal P, Gilbert DJ, Copeland NG, Jenkins NA, Simister NE. Mouse MHC class I-like Fc receptor encoded outside the MHC. J Immunol 151(11):6076-88, 1993. e-Pub 1993. PMID: 7504013.
Rutherford MS, Rock CO, Jenkins NA, Gilbert DJ, Tessner TG, Copeland NG, Jackowski S. The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16. Genomics 18(3):698-701, 1993. e-Pub 1993. PMID: 8307580.
Wilkie TM, Chen Y, Gilbert DJ, Moore KJ, Yu L, Simon MI, Copeland NG, Jenkins NA. Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors. Genomics 18(2):175-84, 1993. e-Pub 1993. PMID: 8288218.
Okazaki T, Yoshida BN, Avraham KB, Wang H, Wuenschell CW, Jenkins NA, Copeland NG, Anderson DJ, Mori N. Molecular diversity of the SCG10/stathmin gene family in the mouse. Genomics 18(2):360-73, 1993. e-Pub 1993. PMID: 8288240.
Cerretti DP, Nelson N, Kozlosky CJ, Morrissey PJ, Copeland NG, Gilbert DJ, Jenkins NA, Dosik JK, Mock BA. The murine homologue of the human interleukin-8 receptor type B maps near the Ity-Lsh-Bcg disease resistance locus. Genomics 18(2):410-3, 1993. e-Pub 1993. PMID: 8288247.
Brott BK, Alessandrini A, Largaespada DA, Copeland NG, Jenkins NA, Crews CM, Erikson RL. MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues. Cell Growth Differ 4(11):921-9, 1993. e-Pub 1993. PMID: 8297798.
Gorbea CM, Marchand P, Jiang W, Copeland NG, Gilbert DJ, Jenkins NA, Bond JS. Cloning, expression, and chromosomal localization of the mouse meprin beta subunit. J Biol Chem 268(28):21035-43, 1993. e-Pub 1993. PMID: 8407940.
Copeland NG, Gilbert DJ, Jenkins NA, Nadeau JH, Eppig JT, Maltais LJ, Miller JC, Dietrich WF, Steen RG, Lincoln SE. Genome maps IV 1993. Wall chart. Science 262(5130):67-82, 1993. e-Pub 1993. PMID: 8211131.
Goodwin RG, Din WS, Davis-Smith T, Anderson DM, Gimpel SD, Sato TA, Maliszewski CR, Brannan CI, Copeland NG, Jenkins NA, et al.. Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor. Eur J Immunol 23(10):2631-41, 1993. e-Pub 1993. PMID: 8405064.
Gearing DP, Druck T, Huebner K, Overhauser J, Gilbert DJ, Copeland NG, Jenkins NA. The leukemia inhibitory factor receptor (LIFR) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13. Genomics 18(1):148-50, 1993. e-Pub 1993. PMID: 8276403.
Webb GC, Jenkins NA, Largaespada DA, Copeland NG, Fernandez CS, Bowtell DD. Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively. Genomics 18(1):14-9, 1993. e-Pub 1993. PMID: 8276400.
Harada N, Santos-Argumedo L, Chang R, Grimaldi JC, Lund FE, Brannan CI, Copeland NG, Jenkins NA, Heath AW, Parkhouse RM, et al.. Expression cloning of a cDNA encoding a novel murine B cell activation marker. Homology to human CD38. J Immunol 151(6):3111-8, 1993. e-Pub 1993. PMID: 8376770.
Matsunami H, Miyatani S, Inoue T, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M. Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene. J Cell Sci 106 ( Pt 1):401-9, 1993. e-Pub 1993. PMID: 8270638.
Gupta K, Copeland NG, Gilbert DJ, Jenkins NA, Gray DA. Unp, a mouse gene related to the tre oncogene. Oncogene 8(8):2307-10, 1993. e-Pub 1993. PMID: 8336951.
Hodgkinson CA, Moore KJ, Nakayama A, Steingrímsson E, Copeland NG, Jenkins NA, Arnheiter H. Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell 74(2):395-404, 1993. e-Pub 1993. PMID: 8343963.
Rawlings DJ, Saffran DC, Tsukada S, Largaespada DA, Grimaldi JC, Cohen L, Mohr RN, Bazan JF, Howard M, Copeland NG, et al.. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science 261(5119):358-61, 1993. e-Pub 1993. PMID: 8332901.
Smith CA, Gruss HJ, Davis T, Anderson D, Farrah T, Baker E, Sutherland GR, Brannan CI, Copeland NG, Jenkins NA, et al.. CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell 73(7):1349-60, 1993. e-Pub 1993. PMID: 8391931.
Law CL, Torres RM, Sundberg HA, Parkhouse RM, Brannan CI, Copeland NG, Jenkins NA, Clark EA. Organization of the murine Cd22 locus. Mapping to chromosome 7 and characterization of two alleles. J Immunol 151(1):175-87, 1993. e-Pub 1993. PMID: 8100843.
Godfrey P, Rahal JO, Beamer WG, Copeland NG, Jenkins NA, Mayo KE. GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function. Nat Genet 4(3):227-32, 1993. e-Pub 1993. PMID: 8395283.
McKenzie AN, Li X, Largaespada DA, Sato A, Kaneda A, Zurawski SM, Doyle EL, Milatovich A, Francke U, Copeland NG, et al.. Structural comparison and chromosomal localization of the human and mouse IL-13 genes. J Immunol 150(12):5436-44, 1993. e-Pub 1993. PMID: 8099936.
Li K, Christiano AM, Copeland NG, Gilbert DJ, Chu ML, Jenkins NA, Uitto J. cDNA cloning and chromosomal mapping of the mouse type VII collagen gene (Col7a1): evidence for rapid evolutionary divergence of the gene. Genomics 16(3):733-9, 1993. e-Pub 1993. PMID: 8325648.
Tessarollo L, Tsoulfas P, Martin-Zanca D, Gilbert DJ, Jenkins NA, Copeland NG, Parada LF. trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues. Development 118(2):463-75, 1993. e-Pub 1993. PMID: 8223273.
Gorski DH, LePage DF, Patel CV, Copeland NG, Jenkins NA, Walsh K. Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells. Mol Cell Biol 13(6):3722-33, 1993. e-Pub 1993. PMID: 8098844.
Jiang W, Sadler PM, Jenkins NA, Gilbert DJ, Copeland NG, Bond JS. Tissue-specific expression and chromosomal localization of the alpha subunit of mouse meprin A. J Biol Chem 268(14):10380-5, 1993. e-Pub 1993. PMID: 7683677.
Young HA, Jenkins NA, Copeland NG, Simek S, Lerman MI, Zbar B, Glenn G, Ortaldo JR, Anderson SK. Localization of a novel natural killer triggering receptor locus to human chromosome 3p23-p21 and mouse chromosome 9. Genomics 16(2):548-9, 1993. e-Pub 1993. PMID: 8314596.
Yokoyama T, Copeland NG, Jenkins NA, Montgomery CA, Elder FF, Overbeek PA. Reversal of left-right asymmetry: a situs inversus mutation. Science 260(5108):679-82, 1993. e-Pub 1993. PMID: 8480178.
Okamoto K, Wakamiya M, Noji S, Koyama E, Taniguchi S, Takemura R, Copeland NG, Gilbert DJ, Jenkins NA, Muramatsu M, et al.. A novel class of murine POU gene predominantly expressed in central nervous system. J Biol Chem 268(10):7449-57, 1993. e-Pub 1993. PMID: 8463278.
Gilbert DJ, Neumann PE, Taylor BA, Jenkins NA, Copeland NG. Susceptibility of AKXD recombinant inbred mouse strains to lymphomas. J Virol 67(4):2083-90, 1993. e-Pub 1993. PMID: 8383230.
Komuro I, Schalling M, Jahn L, Bodmer R, Jenkins NA, Copeland NG, Izumo S. Gtx: a novel murine homeobox-containing gene, expressed specifically in glial cells of the brain and germ cells of testis, has a transcriptional repressor activity in vitro for a serum-inducible promoter. EMBO J 12(4):1387-401, 1993. e-Pub 1993. PMID: 8096811.
Porter BE, Justice MJ, Copeland NG, Jenkins NA, Hunter DD, Merlie JP, Sanes JR. S-laminin: mapping to mouse chromosome 9 and expression in the linked mutants tippy and ducky. Genomics 16(1):278-81, 1993. e-Pub 1993. PMID: 8486374.
Heusel JW, Scarpati EM, Jenkins NA, Gilbert DJ, Copeland NG, Shapiro SD, Ley TJ. Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene. Blood 81(6):1614-23, 1993. e-Pub 1993. PMID: 8453108.
Tsui FW, Tsui HW, Mok S, Mlinaric I, Copeland NG, Gilbert DJ, Jenkins NA, Siminovitch KA. Molecular characterization and mapping of murine genes encoding three members of the stefin family of cysteine proteinase inhibitors. Genomics 15(3):507-14, 1993. e-Pub 1993. PMID: 8468045.
Allen RC, Armitage RJ, Conley ME, Rosenblatt H, Jenkins NA, Copeland NG, Bedell MA, Edelhoff S, Disteche CM, Simoneaux DK, et al.. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science 259(5097):990-3, 1993. e-Pub 1993. PMID: 7679801.
Mano H, Mano K, Tang B, Koehler M, Yi T, Gilbert DJ, Jenkins NA, Copeland NG, Ihle JN. Expression of a novel form of Tec kinase in hematopoietic cells and mapping of the gene to chromosome 5 near Kit. Oncogene 8(2):417-24, 1993. e-Pub 1993. PMID: 7678927.
Gartner J, Kearns W, Rosenberg C, Pearson P, Copeland NG, Gilbert DJ, Jenkins NA, Valle D. Localization of the 70-kDa peroxisomal membrane protein to human 1p21-p22 and mouse 3. Genomics 15(2):412-4, 1993. e-Pub 1993. PMID: 8449508.
Wilson JB, Ferguson MW, Jenkins NA, Lock LF, Copeland NG, Levine AJ. Transgenic mouse model of X-linked cleft palate. Cell Growth Differ 4(2):67-76, 1993. e-Pub 1993. PMID: 8494785.
del Amo FF, Gendron-Maguire M, Swiatek PJ, Jenkins NA, Copeland NG, Gridley T. Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch. Genomics 15(2):259-64, 1993. e-Pub 1993. PMID: 8449489.
Goldsborough AS, Healy LE, Copeland NG, Gilbert DJ, Jenkins NA, Willison KR, Ashworth A. Cloning, chromosomal localization and expression pattern of the POU domain gene Oct-11. Nucleic Acids Res 21(1):127-34, 1993. e-Pub 1993. PMID: 8441607.
Copeland NG, Gilbert DJ, Li K, Sawamura D, Giudice GJ, Chu ML, Jenkins NA, Uitto J. Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes. Genomics 15(1):180-1, 1993. e-Pub 1993. PMID: 8432531.
Taguchi T, Bellacosa A, Zhou JY, Gilbert DJ, Lazo PA, Copeland NG, Jenkins NA, Tsichlis PN, Testa JR. Chromosomal localization of the Ox-44 (CD53) leukocyte antigen gene in man and rodents. Cytogenet Cell Genet 64(3-4):217-21, 1993. e-Pub 1993. PMID: 8404042.
Li YS, Hoffman RM, Le Beau MM, Espinosa R 3rd, Jenkins NA, Gilbert DJ, Copeland NG, Deuel TF. Characterization of the human pleiotrophin gene. Promoter region and chromosomal localization. J Biol Chem 267(36):26011-6, 1992. e-Pub 1992. PMID: 1464612.
Leff SE, Brannan CI, Reed ML, Ozcelik T, Francke U, Copeland NG, Jenkins NA. Maternal imprinting of the mouse Snrpn gene and conserved linkage homology with the human Prader-Willi syndrome region. Nat Genet 2(4):259-64, 1992. e-Pub 1992. PMID: 1303276.
Cattanach BM, Barr JA, Evans EP, Burtenshaw M, Beechey CV, Leff SE, Brannan CI, Copeland NG, Jenkins NA, Jones J. A candidate mouse model for Prader-Willi syndrome which shows an absence of Snrpn expression. Nat Genet 2(4):270-4, 1992. e-Pub 1992. PMID: 1303278.
Nett MA, Cerretti DP, Berson DR, Seavitt J, Gilbert DJ, Jenkins NA, Copeland NG, Black RA, Chaplin DD. Molecular cloning of the murine IL-1 beta converting enzyme cDNA. J Immunol 149(10):3254-9, 1992. e-Pub 1992. PMID: 1431103.
Barker CS, Bear SE, Keler T, Copeland NG, Gilbert DJ, Jenkins NA, Yeung RS, Tsichlis PN. Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma. J Virol 66(11):6763-8, 1992. e-Pub 1992. PMID: 1404614.
Yi T, Gilbert DJ, Jenkins NA, Copeland NG, Ihle JN. Assignment of a novel protein tyrosine phosphatase gene (Hcph) to mouse chromosome 6. Genomics 14(3):793-5, 1992. e-Pub 1992. PMID: 1427910.
Kingsley DM, Bland AE, Grubber JM, Marker PC, Russell LB, Copeland NG, Jenkins NA. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF beta superfamily. Cell 71(3):399-410, 1992. e-Pub 1992. PMID: 1339316.
Brannan CI, Bedell MA, Resnick JL, Eppig JJ, Handel MA, Williams DE, Lyman SD, Donovan PJ, Jenkins NA, Copeland NG. Developmental abnormalities in Steel17H mice result from a splicing defect in the steel factor cytoplasmic tail. Genes Dev 6(10):1832-42, 1992. e-Pub 1992. PMID: 1383087.
Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M. Genomic structure and chromosomal mapping of the mouse N-cadherin gene. Proc Natl Acad Sci U S A 89(18):8443-7, 1992. e-Pub 1992. PMID: 1528849.
Gorman DM, Itoh N, Jenkins NA, Gilbert DJ, Copeland NG, Miyajima A. Chromosomal localization and organization of the murine genes encoding the beta subunits (AIC2A and AIC2B) of the interleukin 3, granulocyte/macrophage colony-stimulating factor, and interleukin 5 receptors. J Biol Chem 267(22):15842-8, 1992. e-Pub 1992. PMID: 1386365.
Foroni L, Boehm T, White L, Forster A, Sherrington P, Liao XB, Brannan CI, Jenkins NA, Copeland NG, Rabbitts TH. The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development. J Mol Biol 226(3):747-61, 1992. e-Pub 1992. PMID: 1507224.
Karls U, Muller U, Gilbert DJ, Copeland NG, Jenkins NA, Harbers K. Structure, expression, and chromosome location of the gene for the beta subunit of brain-specific Ca2+/calmodulin-dependent protein kinase II identified by transgene integration in an embryonic lethal mouse mutant. Mol Cell Biol 12(8):3644-52, 1992. e-Pub 1992. PMID: 1321343.
Copeland NG, Gilbert DJ, Chretien M, Seidah NG, Jenkins NA. Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes. Genomics 13(4):1356-8, 1992. e-Pub 1992. PMID: 1354647.
Cole TJ, Copeland NG, Gilbert DJ, Jenkins NA, Schutz G, Ruppert S. The mouse CREB (cAMP responsive element binding protein) gene: structure, promoter analysis, and chromosomal localization. Genomics 13(4):974-82, 1992. e-Pub 1992. PMID: 1387109.
Degen SJ, Gilbert DJ, Jenkins NA, Copeland NG. Assignment of the gene coding for hepatocyte growth factor-like protein to mouse chromosome 9. Genomics 13(4):1368-9, 1992. e-Pub 1992. PMID: 1354648.
Brannan CI, Gilbert DJ, Ceci JD, Matsuda Y, Chapman VM, Mercer JA, Eisen H, Johnston LA, Copeland NG, Jenkins NA. An interspecific linkage map of mouse chromosome 15 positioned with respect to the centromere. Genomics 13(4):1075-81, 1992. e-Pub 1992. PMID: 1354638.
Disteche CM, Brannan CI, Larsen A, Adler DA, Schorderet DF, Gearing D, Copeland NG, Jenkins NA, Park LS. The human pseudoautosomal GM-CSF receptor alpha subunit gene is autosomal in mouse. Nat Genet 1(5):333-6, 1992. e-Pub 1992. PMID: 1363815.
Ludwig T, Ruther U, Metzger R, Copeland NG, Jenkins NA, Lobel P, Hoflack B. Gene and pseudogene of the mouse cation-dependent mannose 6-phosphate receptor. Genomic organization, expression, and chromosomal localization. J Biol Chem 267(17):12211-9, 1992. e-Pub 1992. PMID: 1376319.
Kim JM, Brannan CI, Copeland NG, Jenkins NA, Khan TA, Moore KW. Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes. J Immunol 148(11):3618-23, 1992. e-Pub 1992. PMID: 1350294.
Avraham KB, Prezioso VR, Chen WS, Lai E, Sladek FM, Zhong W, Darnell JE Jr, Jenkins NA, Copeland NG. Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3 alpha, HNF-3 beta, HNF-3 gamma, and HNF-4. Genomics 13(2):264-8, 1992. e-Pub 1992. PMID: 1612587.
Lock LF, Pines J, Hunter T, Gilbert DJ, Gopalan G, Jenkins NA, Copeland NG, Donovan PJ. A single cyclin A gene and multiple cyclin B1-related sequences are dispersed in the mouse genome. Genomics 13(2):415-24, 1992. e-Pub 1992. PMID: 1535334.
Cebra-Thomas JA, Tsai JY, Pilder SH, Copeland NG, Jenkins NA, Silver LM. Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting. Genomics 13(2):444-6, 1992. e-Pub 1992. PMID: 1612602.
MacGregor TM, Copeland NG, Jenkins NA, Giguere V. The murine gene for cellular retinoic acid-binding protein type II. Genomic organization, chromosomal localization, and post-transcriptional regulation by retinoic acid. J Biol Chem 267(11):7777-83, 1992. e-Pub 1992. PMID: 1313808.
Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356(6367):314-7, 1992. e-Pub 1992. PMID: 1372394.
Shapiro SD, Griffin GL, Gilbert DJ, Jenkins NA, Copeland NG, Welgus HG, Senior RM, Ley TJ. Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase. J Biol Chem 267(7):4664-71, 1992. e-Pub 1992. PMID: 1537850.
Spitkovsky DD, Royer-Pokora B, Delius H, Kisseljov F, Jenkins NA, Gilbert DJ, Copeland NG, Royer HD. Tissue restricted expression and chromosomal localization of the YB-1 gene encoding a 42 kD nuclear CCAAT binding protein. Nucleic Acids Res 20(4):797-803, 1992. e-Pub 1992. PMID: 1542575.
Watanabe-Fukunaga R, Brannan CI, Itoh N, Yonehara S, Copeland NG, Jenkins NA, Nagata S. The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol 148(4):1274-9, 1992. e-Pub 1992. PMID: 1371136.
Jackson IJ, Chambers DM, Tsukamoto K, Copeland NG, Gilbert DJ, Jenkins NA, Hearing V. A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus. EMBO J 11(2):527-35, 1992. e-Pub 1992. PMID: 1537334.
Moore KJ, D'Amore-Bruno MA, Korfhagen TR, Glasser SW, Whitsett JA, Jenkins NA, Copeland NG. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics 12(2):388-93, 1992. e-Pub 1992. PMID: 1346779.
Spence SE, Gilbert DJ, Harris BS, Davisson MT, Copeland NG, Jenkins NA. Genetic localization of Hao-1, blind-sterile (bs), and Emv-13 on mouse chromosome 2. Genomics 12(2):403-4, 1992. e-Pub 1992. PMID: 1310954.
Haefliger JA, Bruzzone R, Jenkins NA, Gilbert DJ, Copeland NG, Paul DL. Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping. J Biol Chem 267(3):2057-64, 1992. e-Pub 1992. PMID: 1370487.
Kahn T, Friesl H, Copeland NG, Gilbert DJ, Jenkins NA, Gissmann L, Kramer J, zur Hausen H. Molecular cloning, analysis, and chromosomal localization of a mouse genomic sequence related to the human papillomavirus type 18 E5 region. Mol Carcinog 6(2):88-99, 1992. e-Pub 1992. PMID: 1326990.
Singh G, Kaur S, Stock JL, Jenkins NA, Gilbert DJ, Copeland NG, Potter SS. Identification of 10 murine homeobox genes. Proc Natl Acad Sci U S A 88(23):10706-10, 1991. e-Pub 1991. PMID: 1683707.
Singh G, Supp DM, Schreiner C, McNeish J, Merker HJ, Copeland NG, Jenkins NA, Potter SS, Scott W. legless insertional mutation: morphological, molecular, and genetic characterization. Genes Dev 5(12A):2245-55, 1991. e-Pub 1991. PMID: 1748282.
Askew DS, Bartholomew C, Buchberg AM, Valentine MB, Jenkins NA, Copeland NG, Ihle JN. His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia. Oncogene 6(11):2041-7, 1991. e-Pub 1991. PMID: 1682866.
Sun XH, Copeland NG, Jenkins NA, Baltimore D. Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins. Mol Cell Biol 11(11):5603-11, 1991. e-Pub 1991. PMID: 1922066.
Lawler J, Duquette M, Ferro P, Copeland NG, Gilbert DJ, Jenkins NA. Characterization of the murine thrombospondin gene. Genomics 11(3):587-600, 1991. e-Pub 1991. PMID: 1774063.
Kwon BS, Chintamaneni C, Kozak CA, Copeland NG, Gilbert DJ, Jenkins N, Barton D, Francke U, Kobayashi Y, Kim KK. A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12. Proc Natl Acad Sci U S A 88(20):9228-32, 1991. e-Pub 1991. PMID: 1924386.
Matthews W, Jordan CT, Gavin M, Jenkins NA, Copeland NG, Lemischka IR. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci U S A 88(20):9026-30, 1991. e-Pub 1991. PMID: 1717995.
Skalnik DG, Dorfman DM, Perkins AS, Jenkins NA, Copeland NG, Orkin SH. Targeting of transgene expression to monocyte/macrophages by the gp91-phox promoter and consequent histiocytic malignancies. Proc Natl Acad Sci U S A 88(19):8505-9, 1991. e-Pub 1991. PMID: 1656446.
Oettinger HF, Streeter H, Lose E, Copeland NG, Gilbert DJ, Justice MJ, Jenkins NA, Mohandas T, Bernfield M. Chromosome mapping of the murine syndecan gene. Genomics 11(2):334-8, 1991. e-Pub 1991. PMID: 1769649.
Jenkins NA, Mattei MG, Gilbert DJ, Linard CG, Mbikay M, Chretien M, Copeland NG. Assignment of secretogranin I locus to mouse chromosome 2 by in situ hybridization and interspecific backcross analysis. Genomics 11(2):479-80, 1991. e-Pub 1991. PMID: 1685143.
Keshet E, Lyman SD, Williams DE, Anderson DM, Jenkins NA, Copeland NG, Parada LF. Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development. EMBO J 10(9):2425-35, 1991. e-Pub 1991. PMID: 1714375.
Hogan A, Heyner S, Charron MJ, Copeland NG, Gilbert DJ, Jenkins NA, Thorens B, Schultz GA. Glucose transporter gene expression in early mouse embryos. Development 113(1):363-72, 1991. e-Pub 1991. PMID: 1765007.
Tominaga S, Jenkins NA, Gilbert DJ, Copeland NG, Tetsuka T. Molecular cloning of the murine ST2 gene. Characterization and chromosomal mapping. Biochim Biophys Acta 1090(1):1-8, 1991. e-Pub 1991. PMID: 1832015.
Hatta M, Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M. Genomic organization and chromosomal mapping of the mouse P-cadherin gene. Nucleic Acids Res 19(16):4437-41, 1991. e-Pub 1991. PMID: 1886768.
Benovic JL, Onorato JJ, Arriza JL, Stone WC, Lohse M, Jenkins NA, Gilbert DJ, Copeland NG, Caron MG, Lefkowitz RJ. Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family. J Biol Chem 266(23):14939-46, 1991. e-Pub 1991. PMID: 1869533.
Siracusa LD, Alvord WG, Bickmore WA, Jenkins NA, Copeland NG. Interspecific backcross mice show sex-specific differences in allelic inheritance. Genetics 128(4):813-21, 1991. e-Pub 1991. PMID: 1916246.
Bressan A, Somma MP, Lewis J, Santolamazza C, Copeland NG, Gilbert DJ, Jenkins NA, Lavia P. Characterization of the opposite-strand genes from the mouse bidirectionally transcribed HTF9 locus. Gene 103(2):201-9, 1991. e-Pub 1991. PMID: 1889746.
Pritchard MA, Baker E, Whitmore SA, Sutherland GR, Idzerda RL, Park LS, Cosman D, Jenkins NA, Gilbert DJ, Copeland NG, et al.. The interleukin-4 receptor gene (IL4R) maps to 16p11.2-16p12.1 in human and to the distal region of mouse chromosome 7. Genomics 10(3):801-6, 1991. e-Pub 1991. PMID: 1679753.
Brannan CI, Lyman SD, Williams DE, Eisenman J, Anderson DM, Cosman D, Bedell MA, Jenkins NA, Copeland NG. Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains. Proc Natl Acad Sci U S A 88(11):4671-4, 1991. e-Pub 1991. PMID: 1711207.
Kuo SS, Mellentin JD, Copeland NG, Gilbert DJ, Jenkins NA, Cleary ML. Structure, chromosome mapping, and expression of the mouse Lyl-1 gene. Oncogene 6(6):961-8, 1991. e-Pub 1991. PMID: 2067848.
Goodwin RG, Anderson D, Jerzy R, Davis T, Brannan CI, Copeland NG, Jenkins NA, Smith CA. Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor. Mol Cell Biol 11(6):3020-6, 1991. e-Pub 1991. PMID: 1645445.
Cox RD, Copeland NG, Jenkins NA, Lehrach H. Interspersed repetitive element polymerase chain reaction product mapping using a mouse interspecific backcross. Genomics 10(2):375-84, 1991. e-Pub 1991. PMID: 2071145.
Siracusa LD, Rosner MH, Vigano MA, Gilbert DJ, Staudt LM, Copeland NG, Jenkins NA. Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome. Genomics 10(2):313-26, 1991. e-Pub 1991. PMID: 1676977.
Perkins AS, Fishel R, Jenkins NA, Copeland NG. Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein. Mol Cell Biol 11(5):2665-74, 1991. e-Pub 1991. PMID: 2017172.
Allen JD, Lints T, Jenkins NA, Copeland NG, Strasser A, Harvey RP, Adams JM. Novel murine homeo box gene on chromosome 1 expressed in specific hematopoietic lineages and during embryogenesis. Genes Dev 5(4):509-20, 1991. e-Pub 1991. PMID: 1672660.
Kaelbling M, Eddy R, Shows TB, Copeland NG, Gilbert DJ, Jenkins NA, Klinger HP, O'Hara B. Localization of the human gene allowing infection by gibbon ape leukemia virus to human chromosome region 2q11-q14 and to the homologous region on mouse chromosome 2. J Virol 65(4):1743-7, 1991. e-Pub 1991. PMID: 1672162.
Christy BA, Sanders LK, Lau LF, Copeland NG, Jenkins NA, Nathans D. An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene. Proc Natl Acad Sci U S A 88(5):1815-9, 1991. e-Pub 1991. PMID: 2000388.
Mercer JA, Seperack PK, Strobel MC, Copeland NG, Jenkins NA. Novel myosin heavy chain encoded by murine dilute coat colour locus. Nature 349(6311):709-13, 1991. e-Pub 1991. PMID: 1996138.
Perkins AS, Mercer JA, Jenkins NA, Copeland NG. Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development. Development 111(2):479-87, 1991. e-Pub 1991. PMID: 1893871.
Jenkins NA, Justice MJ, Gilbert DJ, Chu ML, Copeland NG. Nidogen/entactin (Nid) maps to the proximal end of mouse chromosome 13 linked to beige (bg) and identifies a new region of homology between mouse and human chromosomes. Genomics 9(2):401-3, 1991. e-Pub 1991. PMID: 1672300.
Ceci JD, Kovatch RM, Swing DA, Jones JM, Snow CM, Rosenberg MP, Jenkins NA, Copeland NG, Meisler MH. Transgenic mice carrying a murine amylase 2.2/SV40 T antigen fusion gene develop pancreatic acinar cell and stomach carcinomas. Oncogene 6(2):323-32, 1991. e-Pub 1991. PMID: 1705690.
Copeland NG, Silan CM, Kingsley DM, Jenkins NA, Cannizzaro LA, Croce CM, Huebner K, Sims JE. Chromosomal location of murine and human IL-1 receptor genes. Genomics 9(1):44-50, 1991. e-Pub 1991. PMID: 1672292.
Siracusa LD, Jenkins NA, Copeland NG. Identification and applications of repetitive probes for gene mapping in the mouse. Genetics 127(1):169-79, 1991. e-Pub 1991. PMID: 1673105.
Freeman M, Ashkenas J, Rees DJ, Kingsley DM, Copeland NG, Jenkins NA, Krieger M. An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors. Proc Natl Acad Sci U S A 87(22):8810-4, 1990. e-Pub 1990. PMID: 1978939.
Budarf M, Huebner K, Emanuel B, Croce CM, Copeland NG, Jenkins NA, D'Andrea AD. Assignment of the erythropoietin receptor (EPOR) gene to mouse chromosome 9 and human chromosome 19. Genomics 8(3):575-8, 1990. e-Pub 1990. PMID: 1962754.
Copeland NG, Gilbert DJ, Cho BC, Donovan PJ, Jenkins NA, Cosman D, Anderson D, Lyman SD, Williams DE. Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles. Cell 63(1):175-83, 1990. e-Pub 1990. PMID: 1698554.
Mercer JA, Jenkins NA, Copeland NG. Lack of ecotropic virus involvement in induction of lymphomas in DBA/2J mice by 7,12-dimethylbenz(a)anthracene. J Virol 64(10):5199-203, 1990. e-Pub 1990. PMID: 2168996.
Buchberg AM, Cleveland LS, Jenkins NA, Copeland NG. Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway. Nature 347(6290):291-4, 1990. e-Pub 1990. PMID: 2169593.
Buchberg AM, Bedigian HG, Jenkins NA, Copeland NG. Evi-2, a common integration site involved in murine myeloid leukemogenesis. Mol Cell Biol 10(9):4658-66, 1990. e-Pub 1990. PMID: 2167436.
Cawthon RM, O'Connell P, Buchberg AM, Viskochil D, Weiss RB, Culver M, Stevens J, Jenkins NA, Copeland NG, White R. Identification and characterization of transcripts from the neurofibromatosis 1 region: the sequence and genomic structure of EVI2 and mapping of other transcripts. Genomics 7(4):555-65, 1990. e-Pub 1990. PMID: 2117566.
Justice MJ, Siracusa LD, Gilbert DJ, Heisterkamp N, Groffen J, Chada K, Silan CM, Copeland NG, Jenkins NA. A genetic linkage map of mouse chromosome 10: localization of eighteen molecular markers using a single interspecific backcross. Genetics 125(4):855-66, 1990. e-Pub 1990. PMID: 1975791.
Viskochil D, Buchberg AM, Xu G, Cawthon RM, Stevens J, Wolff RK, Culver M, Carey JC, Copeland NG, Jenkins NA, et al.. Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus. Cell 62(1):187-92, 1990. e-Pub 1990. PMID: 1694727.
Moore KJ, Swing DA, Copeland NG, Jenkins NA. Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations. Genetics 125(2):421-30, 1990. e-Pub 1990. PMID: 2379821.
de Lapeyriere O, Rosnet O, Benharroch D, Raybaud F, Marchetto S, Planche J, Galland F, Mattei MG, Copeland NG, Jenkins NA, et al.. Structure, chromosome mapping and expression of the murine Fgf-6 gene. Oncogene 5(6):823-31, 1990. e-Pub 1990. PMID: 2193291.
Tsichlis PN, Lee JS, Bear SE, Lazo PA, Patriotis C, Gustafson E, Shinton S, Jenkins NA, Copeland NG, Huebner K, et al.. Activation of multiple genes by provirus integration in the Mlvi-4 locus in T-cell lymphomas induced by Moloney murine leukemia virus. J Virol 64(5):2236-44, 1990. e-Pub 1990. PMID: 1691313.
Mercer JA, Lee KH, Nexo BA, Jenkins NA, Copeland NG. Mechanism of chemical activation of expression of the endogenous ecotropic murine leukemia provirus Emv-3. J Virol 64(5):2245-9, 1990. e-Pub 1990. PMID: 2157883.
Ceci JD, Kingsley DM, Silan CM, Copeland NG, Jenkins NA. An interspecific backcross linkage map of the proximal half of mouse chromosome 14. Genomics 6(4):673-8, 1990. e-Pub 1990. PMID: 1971251.
Siracusa LD, Silan CM, Justice MJ, Mercer JA, Bauskin AR, Ben-Neriah Y, Duboule D, Hastie ND, Copeland NG, Jenkins NA. A molecular genetic linkage map of mouse chromosome 2. Genomics 6(3):491-504, 1990. e-Pub 1990. PMID: 1970329.
Strobel MC, Seperack PK, Copeland NG, Jenkins NA. Molecular analysis of two mouse dilute locus deletion mutations: spontaneous dilute lethal20J and radiation-induced dilute prenatal lethal Aa2 alleles. Mol Cell Biol 10(2):501-9, 1990. e-Pub 1990. PMID: 2300051.
Kingsley DM, Rinchik EM, Russell LB, Ottiger HP, Sutcliffe JG, Copeland NG, Jenkins NA. Genetic ablation of a mouse gene expressed specifically in brain. EMBO J 9(2):395-9, 1990. e-Pub 1990. PMID: 2303033.
Justice MJ, Silan CM, Ceci JD, Buchberg AM, Copeland NG, Jenkins NA. A molecular genetic linkage map of mouse chromosome 13 anchored by the beige (bg) and satin (sa) loci. Genomics 6(2):341-51, 1990. e-Pub 1990. PMID: 2307475.
Lunsford RD, Jenkins NA, Kozak CA, Liang LF, Silan CM, Copeland NG, Dean J. Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins. Genomics 6(1):184-7, 1990. e-Pub 1990. PMID: 1968044.
Ceci JD, Justice MJ, Lock LF, Jenkins NA, Copeland NG. An interspecific backcross linkage map of mouse chromosome 8. Genomics 6(1):72-9, 1990. e-Pub 1990. PMID: 1968046.
Skalnik DG, Dorfman DM, Perkins AS, Jenkins NA, Copeland NG, Orkin SH. Targeting of transgene expression to monocytes by cytochrome b heavy chain gene 5'-flanking sequences induces histiocytic malignancies. Trans Assoc Am Physicians 103:129-36, 1990. e-Pub 1990. PMID: 2132524.
Ceci JD, Siracusa LD, Jenkins NA, Copeland NG. A molecular genetic linkage map of mouse chromosome 4 including the localization of several proto-oncogenes. Genomics 5(4):699-709, 1989. e-Pub 1989. PMID: 2574141.
Young HA, Komschlies KL, Ciccarone V, Beckwith M, Rosenberg M, Jenkins NA, Copeland NG, Durum SK. Expression of human IFN-gamma genomic DNA in transgenic mice. J Immunol 143(7):2389-94, 1989. e-Pub 1989. PMID: 2506285.
Bear SE, Bellacosa A, Lazo PA, Jenkins NA, Copeland NG, Hanson C, Levan G, Tsichlis PN. Provirus insertion in Tpl-1, an Ets-1-related oncogene, is associated with tumor progression in Moloney murine leukemia virus-induced rat thymic lymphomas. Proc Natl Acad Sci U S A 86(19):7495-9, 1989. e-Pub 1989. PMID: 2552446.
Kingsley DM, Jenkins NA, Copeland NG. A molecular genetic linkage map of mouse chromosome 9 with regional localizations for the Gsta, T3g, Ets-1 and Ldlr loci. Genetics 123(1):165-72, 1989. e-Pub 1989. PMID: 2572508.
Regnier DC, Kozak CA, Kingsley DM, Jenkins NA, Copeland NG, Langdon WY, Morse HC 3rd. Identification of two murine loci homologous to the v-cbl oncogene. J Virol 63(9):3678-82, 1989. e-Pub 1989. PMID: 2760978.
Petropoulos CJ, Rosenberg MP, Jenkins NA, Copeland NG, Hughes SH. The chicken skeletal muscle alpha-actin promoter is tissue specific in transgenic mice. Mol Cell Biol 9(9):3785-92, 1989. e-Pub 1989. PMID: 2779567.
Buchberg AM, Jenkins NA, Copeland NG. Localization of the murine macrophage colony-stimulating factor gene to chromosome 3 using interspecific backcross analysis. Genomics 5(2):363-7, 1989. e-Pub 1989. PMID: 2676841.
Siracusa LD, Buchberg AM, Copeland NG, Jenkins NA. Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus. Genetics 122(3):669-79, 1989. e-Pub 1989. PMID: 2759422.
Propst F, Vande Woude GF, Jenkins NA, Copeland NG, Lee BK, Hunt PA, Eicher EM. The Mos proto-oncogene maps near the centromere on mouse chromosome 4. Genomics 5(1):118-23, 1989. e-Pub 1989. PMID: 2570024.
Buchberg AM, Brownell E, Nagata S, Jenkins NA, Copeland NG. A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human. Genetics 122(1):153-61, 1989. e-Pub 1989. PMID: 2567264.
Bartholomew C, Morishita K, Askew D, Buchberg A, Jenkins NA, Copeland NG, Ihle JN. Retroviral insertions in the CB-1/Fim-3 common site of integration activate expression of the Evi-1 gene. Oncogene 4(5):529-34, 1989. e-Pub 1989. PMID: 2542863.
Mock BA, Nordan RP, Justice MJ, Kozak C, Jenkins NA, Copeland NG, Clark SC, Wong GG, Rudikoff S. The murine Il-6 gene maps to the proximal region of chromosome 5. J Immunol 142(4):1372-6, 1989. e-Pub 1989. PMID: 2563387.
Spence SE, Gilbert DJ, Swing DA, Copeland NG, Jenkins NA. Spontaneous germ line virus infection and retroviral insertional mutagenesis in eighteen transgenic Srev lines of mice. Mol Cell Biol 9(1):177-84, 1989. e-Pub 1989. PMID: 2927391.
Hill RE, Jones PF, Rees AR, Sime CM, Justice MJ, Copeland NG, Jenkins NA, Graham E, Davidson DR. A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1. Genes Dev 3(1):26-37, 1989. e-Pub 1989. PMID: 2565278.
Copeland NG, Lock LF, Spence SE, Moore KJ, Swing DA, Gilbert DJ, Jenkins NA. Spontaneous germ-line ecotropic murine leukemia virus infection: implications for retroviral insertional mutagenesis and germ-line gene transfer. Prog Nucleic Acid Res Mol Biol 36:221-34, 1989. e-Pub 1989. PMID: 2544009.
Lock LF, Keshet E, Gilbert DJ, Jenkins NA, Copeland NG. Studies of the mechanism of spontaneous germline ecotropic provirus acquisition in mice. EMBO J 7(13):4169-77, 1988. e-Pub 1988. PMID: 2854055.
Moore KJ, Seperack PK, Strobel MC, Swing DA, Copeland NG, Jenkins NA. Dilute suppressor dsu acts semidominantly to suppress the coat color phenotype of a deletion mutation, dl20J, of the murine dilute locus. Proc Natl Acad Sci U S A 85(21):8131-5, 1988. e-Pub 1988. PMID: 3141922.
Morishita K, Parker DS, Mucenski ML, Jenkins NA, Copeland NG, Ihle JN. Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines. Cell 54(6):831-40, 1988. e-Pub 1988. PMID: 2842066.
Moore KJ, Swing DA, Rinchik EM, Mucenski ML, Buchberg AM, Copeland NG, Jenkins NA. The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln. Genetics 119(4):933-41, 1988. e-Pub 1988. PMID: 3410303.
Mucenski ML, Bedigian HG, Shull MM, Copeland NG, Jenkins NA. Comparative molecular genetic analysis of lymphomas from six inbred mouse strains. J Virol 62(3):839-46, 1988. e-Pub 1988. PMID: 2828679.
Propst F, Rosenberg MP, Oskarsson MK, Russell LB, Nguyen-Huu MC, Nadeau J, Jenkins NA, Copeland NG, Vande Woude GF. Genetic analysis and developmental regulation of testis-specific RNA expression of Mos, Abl, actin and Hox-1.4. Oncogene 2(3):227-33, 1988. e-Pub 1988. PMID: 2895445.
Keshet E, Rosenberg MP, Mercer JA, Propst F, Vande Woude GF, Jenkins NA, Copeland NG. Developmental regulation of ovarian-specific Mos expression. Oncogene 2(3):235-40, 1988. e-Pub 1988. PMID: 3353114.
Mucenski ML, Taylor BA, Copeland NG, Jenkins NA. Chromosomal location of Evi-1, a common site of ecotropic viral integration in AKXD murine myeloid tumors. Oncogene Res 2(3):219-33, 1988. e-Pub 1988. PMID: 2897103.
Copeland NG, Jenkins NA, Nexo B, Schultz AM, Rein A, Mikkelsen T, Jorgensen P. Poorly expressed endogenous ecotropic provirus of DBA/2 mice encodes a mutant Pr65gag protein that is not myristylated. J Virol 62(2):479-87, 1988. e-Pub 1988. PMID: 2826810.
Seperack PK, Strobel MC, Corrow DJ, Jenkins NA, Copeland NG. Somatic and germ-line reverse mutation rates of the retrovirus-induced dilute coat-color mutation of DBA mice. Proc Natl Acad Sci U S A 85(1):189-92, 1988. e-Pub 1988. PMID: 3422417.
Mucenski ML, Taylor BA, Ihle JN, Hartley JW, Morse HC 3rd, Jenkins NA, Copeland NG. Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors. Mol Cell Biol 8(1):301-8, 1988. e-Pub 1988. PMID: 2827004.
Buchberg AM, Bedigian HG, Taylor BA, Brownell E, Ihle JN, Nagata S, Jenkins NA, Copeland NG. Localization of Evi-2 to chromosome 11: linkage to other proto-oncogene and growth factor loci using interspecific backcross mice. Oncogene Res 2(2):149-65, 1988. e-Pub 1988. PMID: 2851124.
Strobel MC, Seperack PK, Moore KJ, Copeland NG, Jenkins NA. The dilute coat-color locus of mouse chromosome 9. Prog Clin Biol Res 256:297-305, 1988. e-Pub 1988. PMID: 3368491.
Mucenski ML, Taylor BA, Copeland NG, Jenkins NA. Characterization of somatically acquired ecotropic and mink cell focus-forming viruses in lymphomas of AKXD recombinant inbred mice. J Virol 61(9):2929-33, 1987. e-Pub 1987. PMID: 3039180.
Siracusa LD, Russell LB, Eicher EM, Corrow DJ, Copeland NG, Jenkins NA. Genetic organization of the agouti region of the mouse. Genetics 117(1):93-100, 1987. e-Pub 1987. PMID: 3666442.
Siracusa LD, Russell LB, Jenkins NA, Copeland NG. Allelic variation within the Emv-15 locus defines genomic sequences closely linked to the agouti locus on mouse chromosome 2. Genetics 117(1):85-92, 1987. e-Pub 1987. PMID: 2822532.
Mucenski ML, Gilbert DJ, Taylor BA, Jenkins NA, Copeland NG. Common sites of viral integration in lymphomas arising in AKXD recombinant inbred mouse strains. Oncogene Res 2(1):33-48, 1987. e-Pub 1987. PMID: 3505665.
Buchberg AM, Taylor BA, Jenkins NA, Copeland NG. Chromosomal localization of Emv-16 and Emv-17, two closely linked ecotropic proviruses of RF/J mice. J Virol 60(3):1175-8, 1986. e-Pub 1986. PMID: 2878091.
Mucenski ML, Taylor BA, Jenkins NA, Copeland NG. AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas. Mol Cell Biol 6(12):4236-43, 1986. e-Pub 1986. PMID: 3025647.
Rinchik EM, Russell LB, Copeland NG, Jenkins NA. Molecular genetic analysis of the dilute-short ear (d-se) region of the mouse. Genetics 112(2):321-42, 1986. e-Pub 1986. PMID: 3000867.
Jenkins NA, Copeland NG. High frequency germline acquisition of ecotropic MuLV proviruses in SWR/J-RF/J hybrid mice. Cell 43(3 Pt 2):811-9, 1985. e-Pub 1985. PMID: 3000616.
Taylor BA, Rowe L, Jenkins NA, Copeland NG. Chromosomal assignment of two endogenous ecotropic murine leukemia virus proviruses of the AKR/J mouse strain. J Virol 56(1):172-5, 1985. e-Pub 1985. PMID: 2993648.
Hutchison KW, Copeland NG, Jenkins NA. Dilute-coat-color locus of mice: nucleotide sequence analysis of the d+2J and d+Ha revertant alleles. Mol Cell Biol 4(12):2899-904, 1984. e-Pub 1984. PMID: 6098826.
Bedigian HG, Johnson DA, Jenkins NA, Copeland NG, Evans R. Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice. J Virol 51(3):586-94, 1984. e-Pub 1984. PMID: 6088784.
Wejman JC, Taylor BA, Jenkins NA, Copeland NG. Endogenous xenotropic murine leukemia virus-related sequences map to chromosomal regions encoding mouse lymphocyte antigens. J Virol 50(1):237-47, 1984. e-Pub 1984. PMID: 6321791.
Copeland NG, Bedigian HG, Thomas CY, Jenkins NA. DNAs of two molecularly cloned endogenous ecotropic proviruses are poorly infectious in DNA transfection assays. J Virol 49(2):437-44, 1984. e-Pub 1984. PMID: 6319743.
Copeland NG, Hutchison KW, Jenkins NA. Excision of the DBA ecotropic provirus in dilute coat-color revertants of mice occurs by homologous recombination involving the viral LTRs. Cell 33(2):379-87, 1983. e-Pub 1983. PMID: 6305507.
Bedigian HG, Copeland NG, Jenkins NA, Salvatore K, Rodick S. Emv-13 (Akv-3): a noninducible endogenous ecotropic provirus of AKR/J mice. J Virol 46(2):490-7, 1983. e-Pub 1983. PMID: 6188864.
Copeland NG, Jenkins NA, Lee BK. Association of the lethal yellow (Ay) coat color mutation with an ecotropic murine leukemia virus genome. Proc Natl Acad Sci U S A 80(1):247-9, 1983. e-Pub 1983. PMID: 6296870.
Jenkins NA, Copeland NG, Taylor BA, Lee BK. Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J Virol 43(1):26-36, 1982. e-Pub 1982. PMID: 6287001.
Jenkins NA, Copeland NG, Taylor BA, Bedigian HG, Lee BK. Ecotropic murine leukemia virus DNA content of normal and lymphomatous tissues of BXH-2 recombinant inbred mice. J Virol 42(2):379-88, 1982. e-Pub 1982. PMID: 6283161.
Jenkins NA, Copeland NG, Taylor BA, Lee BK. Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome. Nature 293(5831):370-4, 1981. e-Pub 1981. PMID: 6268990.
Copeland NG, Jenkins NA, Cooper GM. Integration of Rous sarcoma virus DNA during transfection. Cell 23(1):51-60, 1981. e-Pub 1981. PMID: 6260381.
Copeland NG, Zelenetz AD, Copper GM. Transformation by subgenomic fragments of Rous sarcoma virus DNA. Cell 19(4):863-70, 1980. e-Pub 1980. PMID: 6247072.
Copeland NG, Cooper GM. Transfection by DNAs of avian erythroblastosis virus and avian myelocytomatosis virus strain MC29. J Virol 33(3):1199-202, 1980. e-Pub 1980. PMID: 6245270.
Cooper GM, Copeland NG, Zelenetz AD, Krontiris T. Transformation of NIH-3T3 mouse cells by avian retroviral DNAs. Cold Spring Harb Symp Quant Biol 44 Pt 2,:1169-76, 1980. e-Pub 1980. PMID: 6253192.
Copeland NG, Zelenetz AD, Cooper GM. Transformation of NIH/3T3 mouse cells by DNA of Rous sarcoma virus. Cell 17(4):993-1002, 1979. e-Pub 1979. PMID: 226269.
Copeland NG, Cooper GM. Transfection by exogenous and endogenous murine retrovirus DNAs. Cell 16(2):347-56, 1979. e-Pub 1979. PMID: 222457.

Review Articles

Takeda H, Jenkins NA, Copeland NG. Identification of cancer driver genes using Sleeping Beauty transposon mutagenesis. Cancer Sci, 2021. e-Pub 2021. PMID: 33783919.
Levine AJ, Jenkins NA, Copeland NG. The Roles of Initiating Truncal Mutations in Human Cancers: The Order of Mutations and Tumor Cell Type Matters. Cancer Cell 35(1):10-15, 2019. e-Pub 2019. PMID: 30645969.
Mann KM, Ying H, Juan J, Jenkins NA, Copeland NG. KRAS-related proteins in pancreatic cancer. Pharmacol Ther 168:29-42, 2016. e-Pub 2016. PMID: 27595930.
Mann MB, Jenkins NA, Copeland NG, Mann KM. Sleeping Beauty mutagenesis: exploiting forward genetic screens for cancer gene discovery. Curr Opin Genet Dev 24:16-22, 2014. e-Pub 2014. PMID: 24657532.
Copeland NG, Jenkins NA. Harnessing transposons for cancer gene discovery. Nat Rev Cancer 10(10):696-706, 2010. e-Pub 2010. PMID: 20844553.
Copeland NG, Jenkins NA. Deciphering the genetic landscape of cancer--from genes to pathways. Trends Genet 25(10):455-62, 2009. e-Pub 2009. PMID: 19818523.
Matesic LE, Copeland NG, Jenkins NA. Itchy mice: the identification of a new pathway for the development of autoimmunity. Curr Top Microbiol Immunol 321:185-200, 2008. e-Pub 2008. PMID: 18727493.
Steingrimsson E, Copeland NG, Jenkins NA. Mouse coat color mutations: from fancy mice to functional genomics. Dev Dyn 235(9):2401-11, 2006. e-Pub 2006. PMID: 16691561.
Dupuy AJ, Jenkins NA, Copeland NG. Sleeping beauty: a novel cancer gene discovery tool. Hum Mol Genet 15 Spec No 1:R75-9, 2006. e-Pub 2006. PMID: 16651372.
Steingrimsson E, Copeland NG, Jenkins NA. Melanocyte stem cell maintenance and hair graying. Cell 121(1):9-12, 2005. e-Pub 2005. PMID: 15820674.
Asefa B, Klarmann KD, Copeland NG, Gilbert DJ, Jenkins NA, Keller JR. The interferon-inducible p200 family of proteins: a perspective on their roles in cell cycle regulation and differentiation. Blood Cells Mol Dis 32(1):155-67, 2004. e-Pub 2004. PMID: 14757431.
Steingrimsson E, Copeland NG, Jenkins NA. Melanocytes and the microphthalmia transcription factor network. Annu Rev Genet 38:365-411, 2004. e-Pub 2004. PMID: 15568981.
Copeland NG, Jenkins NA, Court DL. Recombineering: a powerful new tool for mouse functional genomics. Nat Rev Genet 2(10):769-79, 2001. e-Pub 2001. PMID: 11584293.
Qi CF, Hori M, Taddesse-Heath L, Jenkins NA, Copeland NG, Shen H, Torrey TA, Hartley JW, Chattopadhyay SK, Fredrickson TN, Morse HC. Diffuse large-cell and "true" histiocytic lymphomas of mice. Curr Top Microbiol Immunol 252:301-5, 2000. e-Pub 2000. PMID: 11125488.
O'Brien SJ, Menotti-Raymond M, Murphy WJ, Nash WG, Wienberg J, Stanyon R, Copeland NG, Jenkins NA, Womack JE, Marshall Graves JA. The promise of comparative genomics in mammals. Science 286(5439):458-62, 479-81, 1999. e-Pub 1999. PMID: 10521336.
Copeland NG, Jenkins NA. Myeloid leukemia: disease genes and mouse models. Prog Exp Tumor Res 35:53-63, 1999. e-Pub 1999. PMID: 10377751.
Lopez-Rodriguez C, Aramburu J, Rakeman AS, Copeland NG, Gilbert DJ, Thomas S, Disteche C, Jenkins NA, Rao A. NF-AT5: the NF-AT family of transcription factors expands in a new direction. Cold Spring Harb Symp Quant Biol 64:517-26, 1999. e-Pub 1999. PMID: 11233530.
Fletcher CF, Copeland NG, Jenkins NA. Genetic analysis of voltage-dependent calcium channels. J Bioenerg Biomembr 30(4):387-98, 1998. e-Pub 1998. PMID: 9758334.
Bedell MA, Jenkins NA, Copeland NG. Mouse models of human disease. Part I: techniques and resources for genetic analysis in mice. Genes Dev 11(1):1-10, 1997. e-Pub 1997. PMID: 9000047.
Bedell MA, Largaespada DA, Jenkins NA, Copeland NG. Mouse models of human disease. Part II: recent progress and future directions. Genes Dev 11(1):11-43, 1997. e-Pub 1997. PMID: 9000048.
Largaespada DA, Brannan CI, Shaughnessy JD, Jenkins NA, Copeland NG. The neurofibromatosis type 1 (NF1) tumor suppressor gene and myeloid leukemia. Curr Top Microbiol Immunol 211:233-9, 1996. e-Pub 1996. PMID: 8585954.
Dietrich WF, Copeland NG, Gilbert DJ, Miller JC, Jenkins NA, Lander ES. Mapping the mouse genome: current status and future prospects. Proc Natl Acad Sci U S A 92(24):10849-53, 1995. e-Pub 1995. PMID: 7479896.
Perry WL, Copeland NG, Jenkins NA. The molecular basis for dominant yellow agouti coat color mutations. Bioessays 16(10):705-7, 1994. e-Pub 1994. PMID: 7980472.
Copeland NG, Jenkins NA, Gilbert DJ, Eppig JT, Maltais LJ, Miller JC, Dietrich WF, Weaver A, Lincoln SE, Steen RG. A genetic linkage map of the mouse: current applications and future prospects. Science 262(5130):57-66, 1993. e-Pub 1993. PMID: 8211130.
O'Brien SJ, Womack JE, Lyons LA, Moore KJ, Jenkins NA, Copeland NG. Anchored reference loci for comparative genome mapping in mammals. Nat Genet 3(2):103-12, 1993. e-Pub 1993. PMID: 8499943.
Justice MJ, Jenkins NA, Copeland NG. Recombinant inbred mouse strains: models for disease study. Trends Biotechnol 10(4):120-6, 1992. e-Pub 1992. PMID: 1368097.
Copeland NG, Jenkins NA. Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet 7(4):113-8, 1991. e-Pub 1991. PMID: 2068781.
Lock LF, Jenkins NA, Copeland NG. Mutagenesis of the mouse germline using retroviruses. Curr Top Microbiol Immunol 171:27-41, 1991. e-Pub 1991. PMID: 1667628.
Copeland NG, Jenkins NA. Retroviral integration in murine myeloid tumors to identify Evi-1, a novel locus encoding a zinc-finger protein. Adv Cancer Res 54:141-57, 1990. e-Pub 1990. PMID: 2105003.
Jenkins NA, Strobel MC, Seperack PK, Kingsley DM, Moore KJ, Mercer JA, Russell LB, Copeland NG. A retroviral insertion in the dilute (d) locus provides molecular access to this region of mouse chromosome 9. Prog Nucleic Acid Res Mol Biol 36:207-20, 1989. e-Pub 1989. PMID: 2544008.
Copeland NG, Buchberg AM, Gilbert DJ, Jenkins NA. Recombinant inbred mouse strains: models for studying the molecular genetic basis of myeloid tumorigenesis. Curr Top Microbiol Immunol 149:45-57, 1989. e-Pub 1989. PMID: 2543543.
Jenkins NA, Copeland NG. Transgenic mice in cancer research. Important Adv Oncol:61-77, 1989. e-Pub 1989. PMID: 2651297.
Jenkins NA, Copeland NG. Retroviral DNA content of the mouse genome. Birth Defects Orig Artic Ser 23(3):109-22, 1987. e-Pub 1987. PMID: 3307932.
Copeland NG, Jenkins NA. Eukaryotic transposable elements: probes for identifying and studying genes important in mammalian development. Birth Defects Orig Artic Ser 23(3):123-35, 1987. e-Pub 1987. PMID: 2820527.

Neal G. Copeland, Ph.D.

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Neal G. Copeland, Ph.D.

About Dr. Neal G. Copeland

Present Title & Affiliation

Primary Appointment

Education & Training

Degree-Granting Education

Postgraduate Training

Honors & Awards

Selected Publications

Peer-Reviewed Articles

Review Articles

Other Articles

Patient Reviews

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