Osama Mohamad, M.D., P.h.D.
Department of GU Radiation Oncology, Division of Radiation Oncology
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Genitourinary Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2014 | Emory University, Atlanta, GA, USA, PHD, Stem Cells and Regenerative Neuroscience (MSTP program) |
| 2014 | Emory University, Atlanta, GA, USA, MD, (MSTP program) |
| 2008 | American University of Beirut, Beirut, LBN, BS, Biology |
Postgraduate Training
| 2018-2019 | Chief Resident, Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX |
| 2017-2018 | Visiting Clinician and Researcher, Carbon Ion Therapy, National Institute of Radiological Sciences, Hospital of Charged Particle Therapy, Chiba |
| 2015-2019 | Clinical Residency, Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX |
| 2014-2015 | Clinical Internship, Transitional Year Program, University of Hawaii, Honolulu, HI |
| 2011-2012 | HHMI Fellowship, Certificate Program in Clinical and Translational Research, Emory University, Atlanta, GA |
Board Certifications
| 2021 | American Board of Radiology |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Lichter KE, Charbonneau K, Sabbagh A, Witztum A, Chuter R, Anand C, Thiel CL, Mohamad O. Evaluating the Environmental Impact of Radiation Therapy Using Life Cycle Assessments: A Critical Review. Int J Radiat Oncol Biol Phys 117(3):554-567, 2023. e-Pub 2023. PMID: 37172916.
- Silverwood S, Lichter K, Conway A, Drew T, McComas KN, Zhang S, Gopakumar GM, Abdulbaki H, Smolen KA, Mohamad O, Grover S. Distance Traveled by Patients Globally to Access Radiotherapy: A Systematic Review. Int J Radiat Oncol Biol Phys. e-Pub 2023. PMID: 37949324.
- Baskin A, Cowan JE, Braun A, Lonergan PE, Mohamad O, Washington SL, Zhao S, Broering JM, Cooperberg MR, Breyer BN, Carroll PR. Long-term complications and health-related quality of life outcomes after radical prostatectomy with or without subsequent radiation treatment for prostate cancer. Urol Oncol 41(10):429.e9-429.e14, 2023. e-Pub 2023. PMID: 37407420.
- Sabbagh A, Washington SL, Tilki D, Hong JC, Feng J, Valdes G, Chen MH, Wu J, Huland H, Graefen M, Wiegel T, Böhmer D, Cowan JE, Cooperberg M, Feng FY, Roach M, Trock BJ, Partin AW, D'Amico AV, Carroll PR, Mohamad O. Development and External Validation of a Machine Learning Model for Prediction of Lymph Node Metastasis in Patients with Prostate Cancer. Eur Urol Oncol 6(5):501-507, 2023. e-Pub 2023. PMID: 36868922.
- Shaheen H, Salans MA, Mohamad O, Coleman PW, Ahmed S, Roach M. Age 70 +/- 5 Years and Cancer Specific Outcomes after Treatment of Localized Prostate Cancer: A Systematic Review. Int J Radiat Oncol Biol Phys. e-Pub 2023. PMID: 37788716.
- Mohamad O, Zamboglou C, Zilli T, Murthy V, Aebersold DM, Loblaw A, Guckenberger M, Shelan M. Safety of Ultrahypofractionated Pelvic Nodal Irradiation in the Definitive Management of Prostate Cancer: Systematic Review and Meta-analysis. Int J Radiat Oncol Biol Phys. e-Pub 2023. PMID: 37863241.
- Lonergan PE, Baskin A, Greenberg SA, Mohamad O, Washington SL, Zhao S, Cowan JE, Broering JM, Nguyen HG, Cooperberg MR, Breyer BN, Carroll PR. The Long-term Incidence and Quality of Life Outcomes Associated With Treatment-Related Toxicities of External Beam Radiotherapy for Prostate Cancer. Urology 178:114-119, 2023. e-Pub 2023. PMID: 37244430.
- Sabbagh A, Tilki D, Feng J, Huland H, Graefen M, Wiegel T, Böhmer D, Hong JC, Valdes G, Cowan JE, Cooperberg M, Feng FY, Mohammad T, Shelan M, D'Amico AV, Carroll PR, Mohamad O. Multi-institutional Development and External Validation of a Machine Learning Model for the Prediction of Distant Metastasis in Patients Treated by Salvage Radiotherapy for Biochemical Failure After Radical Prostatectomy. Eur Urol Focus. e-Pub 2023. PMID: 37507248.
- Sadighian M, Hakam N, Amend G, Shaw NM, Tahir P, Allen IE, Nabavizadeh B, Holler J, Shibley W, Li KD, Abbasi B, Bell A, Mohamad O, Breyer BN. Radiation-induced Fistulas in Patients With Prior Pelvic Radiotherapy for Prostate Cancer: A Systematic Review and Meta-analysis. Urology 176:121-126, 2023. e-Pub 2023. PMID: 36963666.
- Sabbagh A, Weiss J, Tawk B, Mohammed MA, Abdulbaki H, Moraes FY, Grover S, Yap ML, Zubizarreta E, Lievens Y, Rodin D, Mohamad O. Hypofractionation Adoption in Prostate Cancer Radiotherapy: Results of an International Survey. JCO Glob Oncol 9:e2300046, 2023. PMID: 37319396.
- Tilki D, Chen MH, Wu J, Huland H, Graefen M, Mohamad O, Cowan JE, Feng FY, Carroll PR, D'Amico AV. Prostate-Specific Antigen Level at the Time of Salvage Therapy After Radical Prostatectomy for Prostate Cancer and the Risk of Death. J Clin Oncol 41(13):2428-2435, 2023. e-Pub 2023. PMID: 36857638.
- Spratt DE, Tang S, Sun Y, Huang HC, Chen E, Mohamad O, Armstrong AJ, Tward JD, Nguyen PL, Lang JM, Zhang J, Mitani A, Simko JP, DeVries S, van der Wal D, Pinckaers H, Monson JM, Campbell HA, Wallace J, Ferguson MJ, Bahary JP, Schaeffer EM, NRG Prostate Cancer AI Consortium, Sandler HM, Tran PT, Rodgers JP, Esteva A, Yamashita R, Feng FY. Artificial Intelligence Predictive Model for Hormone Therapy Use in Prostate Cancer. Res Sq, 2023. e-Pub 2023. PMID: 37131691.
- Kwon DH, Shakhnazaryan N, Shui D, Hong JC, Mohamad O, de Kouchkovsky I, Borno HT, Bose R, Chou J, Desai A, Fong L, Friedlander TW, Koshkin VS, Aggarwal RR, Feng FY, Hope TA, Small EJ. Serial stereotactic body radiation therapy for oligometastatic prostate cancer detected by novel PET-based radiotracers. Urol Oncol 41(3):145.e7-145.e15, 2023. e-Pub 2022. PMID: 36435709.
- Esteva A, Feng J, van der Wal D, Huang SC, Simko JP, DeVries S, Chen E, Schaeffer EM, Morgan TM, Sun Y, Ghorbani A, Naik N, Nathawani D, Socher R, Michalski JM, Roach M, Pisansky TM, Monson JM, Naz F, Wallace J, Ferguson MJ, Bahary JP, Zou J, Lungren M, Yeung S, Ross AE, NRG Prostate Cancer AI Consortium, Sandler HM, Tran PT, Spratt DE, Pugh S, Feng FY, Mohamad O. Author Correction: Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials. NPJ Digit Med 6(1):27, 2023. e-Pub 2023. PMID: 36813827.
- Mushonga M, Weiss J, Liu ZA, Nyakabau AM, Mohamad O, Tawk B, Moraes FY, Grover S, Yap ML, Zubizarreta E, Lievens Y, Rodin D. Hypofractionation in Breast Cancer Radiotherapy Across World Bank Income Groups: Results of an International Survey. JCO Glob Oncol 9:e2200127, 2023. PMID: 36706350.
- Ni L, Chen K, Phuong C, Sabbagh AR, Wong AC, Mohamad O, Hsu IC. Outcomes of salvage high dose-rate brachytherapy with or without pelvic external beam radiotherapy in patients with palpable local recurrence of prostate cancer after radical prostatectomy. Brachytherapy 22(3):304-309, 2023. e-Pub 2023. PMID: 36623988.
- Chen D, Song M, Mohamad O, Yu SP. Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells. BMC Cancer 14:716, 2014. e-Pub 2014. PMID: 25255962.
- Wei S, Sun J, Li J, Wang L, Hall CL, Dix TA, Mohamad O, Wei L, Yu SP. Acute and delayed protective effects of pharmacologically induced hypothermia in an intracerebral hemorrhage stroke model of mice. Neuroscience 252:489-500, 2013. e-Pub 2013. PMID: 23912033.
- Drury-Stewart D, Song M, Mohamad O, Guo Y, Gu X, Chen D, Wei L. Highly efficient differentiation of neural precursors from human embryonic stem cells and benefits of transplantation after ischemic stroke in mice. Stem Cell Res Ther 4(4):93, 2013. e-Pub 2013. PMID: 23928330.
- Song M, Mohamad O, Chen D, Yu SP. Coordinated development of voltage-gated Na+ and K+ currents regulates functional maturation of forebrain neurons derived from human induced pluripotent stem cells. Stem Cells Dev 22(10):1551-63, 2013. e-Pub 2013. PMID: 23259973.
- Mohamad O, Song M, Wei L, Yu SP. Regulatory roles of the NMDA receptor GluN3A subunit in locomotion, pain perception and cognitive functions in adult mice. J Physiol 591(1):149-68, 2013. e-Pub 2012. PMID: 23006484.
- Song M, Mohamad O, Gu X, Wei L, Yu SP. Restoration of intracortical and thalamocortical circuits after transplantation of bone marrow mesenchymal stem cells into the ischemic brain of mice. Cell Transplant 22(11):2001-15, 2013. e-Pub 2012. PMID: 23069268.
- Mohamad O, Drury-Stewart D, Song M, Faulkner B, Chen D, Yu SP, Wei L. Vector-free and transgene-free human iPS cells differentiate into functional neurons and enhance functional recovery after ischemic stroke in mice. PLoS One 8(5):e64160, 2013. e-Pub 2013. PMID: 23717557.
- Mohamad O, Yu SP, Chen D, Ogle M, Song M, Wei L. Efficient neuronal differentiation of mouse ES and iPS cells using a rotary cell culture protocol. Differentiation 86(4-5):149-58, 2013. e-Pub 2014. PMID: 24480155.
- Majumder A, Banerjee S, Harrill JA, Machacek DW, Mohamad O, Bacanamwo M, Mundy WR, Wei L, Dhara SK, Stice SL. Neurotrophic effects of leukemia inhibitory factor on neural cells derived from human embryonic stem cells. Stem Cells 30(11):2387-99, 2012. PMID: 22899336.
- Choi KE, Hall CL, Sun JM, Wei L, Mohamad O, Dix TA, Yu SP. A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice. FASEB J 26(7):2799-810, 2012. e-Pub 2012. PMID: 22459147.
- Li J, Yu S, Lu Z, Mohamad O, Wei L. N-methyl-D-aspartate receptor subtype 3A promotes apoptosis in developing mouse brain exposed to hyperoxia. Neural Regen Res 7(4):273-7, 2012. PMID: 25806068.
- Mohamad O, Chen D, Zhang L, Hofmann C, Wei L, Yu SP. Erythropoietin reduces neuronal cell death and hyperalgesia induced by peripheral inflammatory pain in neonatal rats. Mol Pain 7:51, 2011. e-Pub 2011. PMID: 21777449.
- Drury-Stewart D, Song M, Mohamad O, Yu SP, Wei L. Small molecule promoted feeder free and adherent differentiation of functional neurons from human embryonic and induced pluripotent stem cells. J Stem Cells 6(1):1-7, 2011. PMID: 22997841.
- Li Y, Yu SP, Mohamad O, Genetta T, Wei L. Sublethal transient global ischemia stimulates migration of neuroblasts and neurogenesis in mice. Transl Stroke Res 1(3):184-96, 2010. PMID: 21792374.