Pablo C. Okhuysen, M.D., FACP, FIDSA
Department of Infectious Diseases, Infection Control, and Employee Health, Division of Internal Medicine
About Dr. Pablo C. Okhuysen
I have over 30 years’ experience in the study of enteric infectious diseases. I trained as a physician-scientist in Infectious Diseases at The University of Texas Medical School. I am a past Director of the NIH NCRR funded General Clinical Research Center at UT Health/Memorial Hermann Hospital and co-lead the joint UT Houston Medical School NIH CTSA-funded Center for Clinical and Translational Sciences.
I have conducted clinical and translational research in subjects with norovirus infection, travelers’ diarrhea, cryptosporidiosis and HIV and received the Oswald Avery Award for Early Accomplishment from the Infectious Diseases Society of America in 2007. I have gained extensive laboratory research experience in the characterization of bacterial agents of diarrhea, host immune response and genetic susceptibility to enteric infection, as well as with clinical trials with antibiotic and antiviral agents, human experimental challenge studies with enteropathogens and studied naturally acquired intestinal infections in US travelers to developing countries. In 2013, I joined MD Anderson Cancer Center and have established a laboratory dedicated to the study of enteropathogens in patients with cancer. I participate in the NIH funded U19 Genomic Centers for Infectious Diseases Program carrying out studies on enteric pathogens the microbiome in patients with cancer. I also participate in an NIH funded U19 Novel, Alternative Model Systems for Enteric Diseases Program examining host-enteropathogen interactions using human intestinal stem cell derived organoids. I am an active member of the NIH funded Texas Medical Center Digestive Diseases Center.
I am Director for the Onco-Transplant Infectious Diseases Fellowship Program at MDACC and site Program Director for the UT McGovern Medical School /MDACC and the Baylor College of Medicine Infectious Diseases Fellowship Programs.
Present Title & Affiliation
Primary Appointment
Professor, Department of Infectious Diseases, Infection Control and Employee Health, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Fellowship Program Director, Department of Infectious Diseases, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Professor, Division of Infectious Diseases, The University of Texas Medical School, Houston, TX
Adjunct Professor, Department of Epidemiology, Human Genetics and Environmental Health, The University of Texas School of Public Health, Houston, TX
Adjunct Professor of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX
Research Interests
Education & Training
Degree-Granting Education
| 1988 | Universidad Autonoma de Guadalajara, Guadalajara, MEX, MD, Medicine |
Postgraduate Training
| 1991-1994 | Clinical Fellowship, Infectious Diseases, The University of Texas Medical School at Houston, Houston, TX |
| 1989-1991 | Clinical Residency, Internal Medicine, The University of Texas Medical School at Houston, Houston, TX |
| 1988-1989 | Clinical Internship, Internal Medicine, Cook County Hospital, Chicago, IL |
Licenses & Certifications
| 1994 | American Board of Internal Medicine - Infectious Diseases |
| 1994 | American Board of Internal Medicine |
Experience & Service
Faculty Academic Appointments
Associate Faculty, UT Health and MD Anderson Cancer Center, Graduate School of Biological Sciences, Houston, TX, 2010 - 2015
Administrative Appointments/Responsibilities
Program Director Onco-Transplant Infectious Diseases Fellowship, Department of Infectious Diseases, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - Present
Site Program Director - Infectious Diseases, Baylor College of Medicine, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - Present
Site Program Director - McGovern Medical School, Infectious Diseases Fellowship Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - Present
Co-Program Director, Clinical and Translational Research Center (NIH Clinical and Translational Sciences Award-CTSA), The University of Texas Health Science Center, Houston, TX, 2006 - 2009
Program Director, University Clinical Research Center (NIH General Clinical Research Center-GCRC), The University of Texas Medical School at Houston, Houston, TX, 2002 - 2010
Program Director, Infectious Diseases Fellowship Program, The University of Texas Medical School at Houston, Houston, TX, 2002 - 2009
Associate Program Director, Infectious Diseases Fellowship Program, The University of Texas Medical School at Houston, Houston, TX, 1999 - 2002
Minority Clinical Associate Physician, The University of Texas Medical School at Houston, Houston, TX, 1994 - 1997
Other Professional Positions
Member - Internal Medicine Education Committee, UT MD Anderson Cancer Center, Houston, 2020 - Present
Lead, MDACC Clostridium difficile Task Force, Houston, TX, 2016 - Present
Attending Physician, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - Present
Attending Physician, Thomas Street Clinic. Harris County Hospital District, Houston, TX, 1995 - 1997
Attending Physician, The University of Texas Infectious Diseases Clinic, UT Physicians, Houston, TX, 1994 - 2013
Attending Physician, Internal Medicine and Infectious Diseases Services. Lyndon B. Johnson General Hospital, Harris County Hospital District, Houston, TX, 1994 - 2013
Attending Physician, Internal Medicine and Infectious Diseases Services. Memorial Hermann Hospital – Texas Medical Center, Houston, TX, 1994 - 2013
Staff Physician, Harris County Early Intervention HIV Clinic, Harris County Texas Medical Center Clinic, Houston, TX, 1993 - 1994
Institutional Committee Activities
Member, Academic Review Committee, The University of Texas MD Anderson Cancer Center, 2022 - Present
Senator, MD Anderson Cancer Center Faculty Senate, 2016 - Present
Member, Graduate Medical Education, 2015 - Present
Member, Internal Medicine Faculty Review Committee. The University of Texas Medical School at Houston TX, 2005 - 2012
Member, Infection Control Committee. Memorial Hermann Hospital, Houston TX, 2005 - 2013
Member, Medical School Research Committee. The University of Texas Medical School at Houston TX, 2003 - 2008
Member, Infectious Diseases Subcommittee Memorial Hermann Hospital System, Houston TX, 2003 - 2009
Member, Faculty Research Advisory Committee. The University of Texas Health Science Center at Houston TX, 2003 - 2008
Member, Graduate Medical Education Committee. The University of Texas Medical School at Houston TX, 1999 - 2009
Member, Scientific Advisory Committee, University Clinical Research Center at Memorial Hermann Hospital at Houston TX, 1998 - 2002
Member, Institutional Biosafety Committee. The University of Texas Health Science Center Houston TX, 1998 - 2003
Member, Faculty Senate Committee. The University of Texas Medical School at Houston TX, 1998 - 2000
Member, Infectious Diseases Committee, The University of Texas Health Science Center Houston TX, 1996 - 1998
Member, Faculty Student Relations Committee. The University of Texas Health Science Center Houston TX, 1996 - 1999
Consultantships
Member, Board of Scientific Counselors, National Center for Infectious Diseases of the Center for Diseases Control and Prevention, Atlanta GA, 2003 - 2005
Honors & Awards
| 2020 - 2021 | Teacher of the Year Award, Infectious Diseases Fellows MDACC/BCM |
| 2018 | Faculty Excellence in Education, Division of Internal Medicine, UT MDACC |
| 2018 | Division of Internal Medicine Excellence in Education, MDACC |
| 2015 - 2016 | Teacher of the Year Award, Infectious Diseases Fellows MDACC/BCM |
| 2013 - 2014 | Teacher of the Year Award, Infectious Diseases Fellows MDACC/BCM |
| 2012 | Dean's Excellence Award, The University of Texas Medical School at Houston |
| 2011 | Teacher of the Year Award, UTHSC/MDACC ID Fellows |
| 2009 | America's Top Physicians, Guide to America’s Top Physicians |
| 2007 | AOA Honors Medical Society, Delta Chapter |
| 2007 | Oswald Avery Award, Infectious Diseases Society of America |
| 2003 | Honors in International and National Research, The University of Texas Health Science Center at Houston |
| 2001 | Dean's Excellence Award, The University of Texas Medical School at Houston |
| 2000 - Present | Fellow Infectious Diseases Society of America, Infectious Diseases Society of America |
| 1999 | Dean's Excellence Award, The University of Texas Medical School at Houston |
| 1999 - Present | Fellow American College of Physicians, American College of Physicians-American Society of Internal Medicine |
| 1998 | Dean's Excellence Award, The University of Texas Medical School at Houston |
| 1996 | Dean's Excellence Award, The University of Texas Medical School at Houston |
| 1995 | Dean's Excellence Award, The University of Texas Medical School at Houston |
| 1989 | Honors Mention for Clinical Excellence, Cook County Hospital, Chicago IL |
Professional Memberships
Grant & Contract Support
| Date: | 2021 - 2022 |
| Title: | Catalytic RNAs as selective therapeutics for pathogenic microbes in consortia |
| Funding Source: | John Dunn Collaborative Center |
| Role: | Co-Principal Investigator |
| Date: | 2021 - 2026 |
| Title: | Human Biomimetics for Mucosal Infections |
| Funding Source: | NIH/NIAID |
| Role: | Co-Investigator |
| ID: | 2 U19 AI116497-06 |
| Date: | 2020 - 2026 |
| Title: | The Autonomous Monitoring United with living Electronic Therapies (AMULET) |
| Funding Source: | Department of Defense (DOD) |
| Role: | Co-Investigator |
| Date: | 2020 - 2023 |
| Title: | Epidemiology, Clinical features, Metagenomics and Molecular Markers of Infectious Diarrhea due to Multiple Enteropathogens in Cancer and Immunocompromised Patients |
| Funding Source: | BioFire Inc |
| Role: | Principal Investigator |
| Date: | 2020 - 2025 |
| Title: | Understanding and translating the direct and indirect effefcts of the microbiome on treatment response in HPV+ anal cancer (PQ10) |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| ID: | 1R01CA241999-01 |
| Date: | 2020 - 2026 |
| Title: | Assessing the immunomodulatory Role of Commensal and Patogenic Microbiota in HPV mediated cancers |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| Date: | 2019 - 2024 |
| Title: | Mucosal determinants of Cryptosporidium infection |
| Funding Source: | NIH/NIAID |
| Role: | Principal Investigator-MDACC |
| ID: | Application U19 319671 |
| Date: | 2018 - 2019 |
| Title: | Association between timing and choice of antimicrobial therapy for Stenotrophomonas maltophilia |
| Funding Source: | Melinta Pharmaceuticals |
| Role: | Principal Investigator |
| Date: | 2017 - 2021 |
| Title: | BE GONE trial: beans to enrich the gut of obese colorectal cancer survivors |
| Funding Source: | American Cancer Society (ACS) |
| Role: | Co-Investigator |
| ID: | 506778 |
| Date: | 2017 - 2022 |
| Title: | Effects of a dry bean intervention on host-gut microbiota interactions in obese colorectal adenoma patients |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| ID: | R01 12251569 |
| Date: | 2017 - 2018 |
| Title: | Clinical risk factors and microbiology biomarkers associated with Clostridium difficile associated diarrhea (CDAD) severity, recurrence and outcomes in cancer patients |
| Funding Source: | Merck, Co |
| Role: | Co-Principal Investigator |
| Date: | 2015 - 2020 |
| Title: | Emerging Novel Enteroid Models for Understanding Human Enteric Disease |
| Funding Source: | NIH/NIAID |
| Role: | Consultant |
| ID: | AI 116497-01 |
| Date: | 2010 - 2015 |
| Title: | Severe Enteric Disease: Pathogenesis and Response |
| Funding Source: | NIH DMID |
| Role: | Principal Investigator |
| ID: | AI 090873: U19 |
| Date: | 2007 - 2013 |
| Title: | Evaluation of Control Measures Against Diseases Other Than AIDS: Part C – Enteric Challenges Studies |
| Funding Source: | NIH/NIAID |
| Role: | Co-Investigator |
| ID: | N01-AI-25465 |
| Date: | 2006 - 2011 |
| Title: | Center For Clinical and Translational Sciences (CCTS) |
| Funding Source: | NIH/NCRR |
| Role: | Co-Director |
| ID: | 1 UL1 RR024148 |
| Date: | 2006 - 2011 |
| Title: | SCCOR in Thoracic Aortic Aneurysms and Dissections – Core F |
| Funding Source: | NIH |
| Role: | Co-Investigator |
| ID: | 5P50HL083794-02 |
| Date: | 2006 - Present |
| Title: | General Clinical Research Center (GCRC), later subsumed to the CTSA |
| Funding Source: | NIH/NCRR |
| Role: | Program Director |
| ID: | MCAOM01RR02558 |
| Date: | 2004 - 2009 |
| Title: | Health, Education and Discovering Science and Careers |
| Funding Source: | SEPA NCRR Phase I/II |
| Role: | Co-Investigator |
| ID: | R25 RR020543 |
| Date: | 2003 - 2007 |
| Title: | Gene polymorphisms that predispose to infectious diarrhea |
| Funding Source: | NIH DMID |
| Role: | Principal Investigator |
| ID: | R01 AI54948-01 |
| Date: | 2002 - 2004 |
| Title: | Infectivity and virulence of Cryptosporidium non-parvum species in healthy adult volunteers |
| Funding Source: | US Environmental Protection Agency |
| Role: | Co-Principal Investigator |
| Date: | 2000 - 2003 |
| Title: | Infectivity and virulence of Cryptosporidium genotype 1/H oocysts in healthy adults |
| Funding Source: | US Environmental Protection Agency |
| Role: | Co-Principal Investigator |
| Date: | 1998 - 2002 |
| Title: | Subcontract from Tufts University: Establish a correlative dose-response model for human cryptosporidiosis |
| Funding Source: | US Food and Drug Administration |
| Role: | Principal Investigator |
| ID: | FDU 001621-01 |
| Date: | 1997 - 1998 |
| Title: | In vitro and in vivo effect of BMS 193033 on Murine Cryptosporidiosis |
| Funding Source: | Bristol Myers Squibb |
| Role: | Co-Investigator |
| Date: | 1997 - 1998 |
| Title: | C. parvum: Mucosal Response in Healthy Hosts and HIV/AIDS Grant |
| Funding Source: | NIH DMID |
| Role: | Co-Investigator |
| Date: | 1997 - 2006 |
| Title: | Subcontract Baylor College of Medicine Intestinal Cytokines in Human Cryptosporidiosis |
| Funding Source: | NIH DMID |
| Role: | Principal Investigator |
| ID: | R01 AI 41735-01 |
| Date: | 1995 - 1998 |
| Title: | Virulence Factors in C. parvum and Infective Dose in Humans |
| Funding Source: | US Environmental Protection Agency |
| Role: | Co-Investigator |
| ID: | R824759-01-0 |
| Date: | 1994 - 1997 |
| Title: | The Arginine Aminopeptidase of C. parvum, Characterization and Importance in Human Infection |
| Funding Source: | NIH/NCRR |
| Role: | Minority Clinical Associate Physician |
| ID: | MCAOM01RR02558-09 |
Selected Publications
Peer-Reviewed Articles
- Francisco DMA, Zhang L, Jiang Y, Olvera A, Adachi J, Guevara EY, Aitken SL, Garey KW, Peterson CB, Do KA, Dillon R, Obi EN, Jenq R, Okhuysen PC. Risk Factors Associated with Severe Clostridioides difficile Infection in Patients with Cancer. Infect Dis Ther 12(1):209-225, 2023. e-Pub 2022. PMID: 36443547.
- Schwabkey ZI, Wiesnoski DH, Chang CC, Tsai WB, Pham D, Ahmed SS, Hayase T, Ortega Turrubiates MR, El-Himri RK, Sanchez CA, Hayase E, Frenk Oquendo AC, Miyama T, Halsey TM, Heckel BE, Brown AN, Jin Y, Raybaud M, Prasad R, Flores I, McDaniel L, Chapa V, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Fowler S, Conner M, McHugh K, Graf T, Jensen VB, Peterson CB, Do KA, Zhang L, Shi Y, Wang Y, Galloway-Pena JR, Okhuysen PC, Daniel-MacDougall CR, Shono Y, Burgos da Silva M, Peled JU, van den Brink MRM, Ajami N, Wargo JA, Reddy P, Valdivia RH, Davey L, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin RE, Shelburne SA, Molldrem JJ, Jamal MA, Karmouch JL, Jenq RR. Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Sci Transl Med 16(14):eabo3445, 2022. e-Pub 2022. PMID: 36383683.
- Karpinets TV, Wu X, Solley T, El Alam MB, Sims TT, Yoshida-Court K, Lynn E, Ahmed-Kaddar M, Biegert G, Yue J, Song X, Sun H, Petrosino JF, Mezzari MP, Okhuysen P, Eifel PJ, Jhingran A, Lin LL, Schmeler KM, Ramondetta L, Ajami N, Jenq RR, Futreal A, Zhang J, Klopp AH, Colbert LE. Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure. BMC Cancer 22(1):945, 2022. e-Pub 2022. PMID: 36050658.
- Liu C, Amin R, Shatila M, Short N, Altan M, Shah A, Alhalabi O, Okhuysen P, Thomas AS, Wang Y. Clinical characteristics and outcomes of tyrosine kinase inhibitor-related lower GI adverse effects. J Cancer Res Clin Oncol. e-Pub 2022. PMID: 36030431.
- Menon VK, Okhuysen PC, Chappell CL, Mahmoud M, Mahmoud M, Meng Q, Doddapaneni H, Vee V, Han Y, Salvi S, Bhamidipati S, Kottapalli K, Weissenberger G, Shen H, Ross MC, Hoffman KL, Cregeen SJ, Muzny DM, Metcalf GA, Gibbs RA, Petrosino JF, Sedlazeck FJ. Fully resolved assembly of Cryptosporidium parvum. Gigascience 11, 2022. PMID: 35166336.
- Vasavada S, Panneerselvam K, Amin R, Varatharajalu K, Okhuysen PC, Oliva ICG, Wang J, Grivas P, Thomas AS, Wang Y. Clostridioides difficile infection in cancer patients receiving immune checkpoint inhibitors. Ann Gastroenterol 35(4):393-399, 2022. e-Pub 2022. PMID: 35784625.
- Panneerselvam K, Szafron D, Amin RN, Wei D, Tan D, Altan M, Okhuysen PC, Shatila M, Raju GS, Thomas AS, Wang Y. Cytomegalovirus infection among patients with cancer receiving immune checkpoint inhibitors. Ann Gastroenterol 35(5):522-531, 2022. e-Pub 2022. PMID: 36061160.
- Ma W, Gong Z, Abu-Sbeih H, Peng Y, Peng F, Zou F, Charabaty A, Okhuysen PC, McQuade JL, Altan M, Zhang HC, Thomas AS, Wang Y. Outcomes of Immune Checkpoint Inhibitor-Related Diarrhea or Colitis in Cancer Patients with Superimposed Gastrointestinal Infections. Am J Clin Oncol 44(8):402-408, 2021. PMID: 34107499.
- Kondapi DS, Ramani S, Estes MK, Atmar RL, Okhuysen PC. Norovirus in Cancer Patients: A review. Open Forum Infect Dis 14(8):ofab126, 2021. e-Pub 2021. PMID: 34189156.
- Viola GM, Malek AE, Rosen LB, DiNardo AR, Nishiguchi T, Okhuysen PC, Holland SM, Kontoyiannis DP. Disseminated cryptococcosis and anti-granulocyte-macrophage colony-stimulating factor autoantibodies: An underappreciated association. Mycoses 64(6):576-582, 2021. e-Pub 2021. PMID: 33476401.
- Yepez Guevara EA, Aitken SL, Olvera AV, Carlin L, Fernandes KE, Bhatti MM, Garey KW, Adachi J, Okhuysen PC. Clostridioides difficile infection in cancer and immunocompromised patients: Relevance of a two-step diagnostic algorithm and infecting ribotypes on clinical outcomes. Clin Infect Dis 72(10):e460-e465, 2021. e-Pub 2020. PMID: 32803229.
- Olvera A, Carter H, Rajan A, Carlin LG, Yu X, Zeng XL, Shelburne S, Bhatti M, Blutt SE, Shroyer NF, Jenq R, Estes MK, Maresso A, Okhuysen PC. Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients. Clin Infect Dis 18(72):e620-e629, 2021. e-Pub 2021. PMID: 32930708.
- Gogia B, Young AL, O'Brien BJ, Okhuysen PC, Kumar VA. Bihemispheric Cortical Infarcts in an Adult Secondary to Escherichia coli K1 Meningitis. Case Rep Neurol 13(2):572-577, 2021. e-Pub 2021. PMID: 34720964.
- Handley G, Hasbun R, Okhuysen P. Human herpesvirus 6 and central nervous system disease in oncology patients: A retrospective case series and literature review. J Clin Virol 136:104740, 2021. e-Pub 2021. PMID: 33548682.
- Ali H, Khurana S, Ma W, Peng Y, Jiang ZD, DuPont H, Zhang HC, Thomas AS, Okhuysen P, Wang Y. Safety and efficacy of fecal microbiota transplantation to treat and prevent recurrent Clostridioides difficile in cancer patients. J Cancer 12(21):6498-6506, 2021. e-Pub 2021. PMID: 34659541.
- Chakravarti D, Hu B, Baoli Hu, Mao X, Rashid A, Li J, Liao WT, Whitley EM, Dey P, Hou, P, Chang A, Wang G, Spring DJ, Deng, P, Zhao D, Liang X, Lan Z, Lin Y, Sarkar S, Terranova C, Deribe YL, Li J, Blutt SE, Okhuysen P, Zhang J, Sanchez EV, Nielsen OH, Dupont A, Younes M, Patel KR, Shroyer NF, Rai K, Estes MK, Wang YA, Bertuch AA, DePinho RA. Telomere dysfunction activates YAP1 to 1 drive tissue inflammation. Nature Communications. e-Pub 2020.
- Rajan A, Poole N, Carter H, Clark J, Green S, Criss ZK, Robertson MJ, Karandikar U, Magalef-Catala M, Jain N, Wilson RL, Shroyer N, Blutt S, Coarfa C, Song X, Prassad BVV, Amieva MR, Grande-Allen J, Estes MK, Okhuysen, PC, Maresso AW. Enteroaggregative E. coli adherence to human heparin sulfated proteoglycans drives segment and host specific responses to infection. PloS Pathog 16(9). e-Pub 2020.
- Gómez-Sandoval JN, Okhuysen P,Mondragón-Flores R, Escalona-Montaño AR, Magdalena Aguirre-García M. Cellular Identification and In Silico Characterization of Protein Phosphatase 2C (PP2C) of Cryptosporidium parvum. Acta Parasitol 65(9):704-715, 2020. e-Pub 2020.
- Mitra A, Grossman Biegert GW, Delgado AY, Karpinets TV, Solley TN, Mezzari MP, Yoshida-Court K, Petrosino JF, Mikkelson MA, Lin L, Eifel P, Zhang J, Ramondetta LM, Jhingran A, Sims TT, Schmeler K, Okhuysen P, Colbert LE, Klopp AH. Microbial Diversity and Composition Is Associated with Patient-Reported Toxicity during Chemoradiation Therapy for Cervical Cancer. Int J Radiat Oncol Biol Phys 107:163-71. e-Pub 2020. PMID: 31987960.
- Abu-Sbeih H, Ali FS, Chen E, Mallepally N, Luo W, Lu Y, Foo WC, Qiao W, Okhuysen PC, Adachi JA, Hachem RY, Altan M, Jenq RR, Wang Y. Neutropenic Enterocolitis: Clinical Features and Outcomes. Dis Colon Rectum 63(3):381-388. e-Pub 2019. PMID: 31842164.
- Zhang X, Browman G, Siu W, Basen-Engquist KM, Hanash SM, Hoffman KL, Okhuysen PC, Scheet P, Petrosino JF, Kopetz S, Daniel CR. The BE GONE trial study protocol: a randomized crossover dietary intervention of dry beans targeting the gut microbiome of overweight and obese patients with a history of colorectal polyps or cancer. BMC Cancer 19(1):1233, 2019. e-Pub 2019. PMID: 31852462.
- Kuhlmann FM, Martin J, Hazen TH, Vickers TJ, Pashos M, Okhuysen PC, Gómez-Duarte OG, Cebelinski E, Boxrud D, Del Canto F, Vidal R, Qadri F, Mitreva M, Rasko DA, Fleckenstein JM. Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli. PLoS Negl Trop Dis 13(11):e0007825. e-Pub 2019. PMID: 31756188.
- Abu-Sbeih H, Tang T, Ali FS, Luo W, Neelapu SS, Westin JR, Okhuysen PC, Foo WC, Curry JL, Richards DM, Ge PS, Wang Y. Gastrointestinal Adverse Events Observed After Chimeric Antigen Receptor T-Cell Therapy. Am J Clin Oncol 42(10):789-796, 2019. PMID: 31478934.
- Abu-Sbeih H, Herrera LN, Tang T, Altan M, Chaftari AP, Okhuysen PC, Jenq RR, Wang Y. Impact of antibiotic therapy on the development and response to treatment of immune checkpoint inhibitor-mediated diarrhea and colitis. J Immunother Cancer 7(1):242, 2019. e-Pub 2019. PMID: 31488205.
- Galloway-Peña, JR, Peterson CV, Malik F, Sahasrabhojane PV, Shah DP, Brumlow CE, Carlin LG, Chemaly RF, Im JS, Rondon G, Alousi A, Jenq R, Kontoyiannis DK, Shpall EJ, Shelburne SA, Okhuysen PC.. Fecal Microbiome, Metabolites, and Stem Cell Transplant Outcomes: A Single-Center Pilot Study. Open Forum Infectious Diseases, 2019. e-Pub 2019.
- Wang EW, Bhatti M, Cantu S, Okhuysen PC. Diagnosis of Yersinia enterocolitica in Cancer Patients with Diarrhea in the Era of Molecular Diagnostics for Gastrointestinal Infections. Open Forum Infectious Diseases, 2019. e-Pub 2019.
- Abu-Sbeih H, Choi K, Tran CN, Wang X, Lum P, Shuttlesworth G, Stroehlein JR, Okhuysen PC, Wang Y. Recurrent Clostridium difficile infection is associated with treatment failure and prolonged illness in cancer patients. Eur J Gastroenterol Hepatol 31(1):128-134, 2019. PMID: 30339561.
- Yalamanchili H, Dandachi D, Okhuysen PC. Use and Interpretation of Enteropathogen Multiplex Nucleic Acid Amplification Tests in Patients With Suspected Infectious Diarrhea. Gastroenterol Hepatol (N Y) 14(11):646-652, 2018. PMID: 30538605.
- Rajan A, Vela L, Zeng XL, Yu X, Shroyer N, Blutt SE, Poole NM, Carlin LG, Nataro JP, Estes MK, Okhuysen PC, Maresso AW. Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids. MBio 9(1), 2018. e-Pub 2018. PMID: 29463660.
- Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science 359(6371):97-103, 2018. e-Pub 2017. PMID: 29097493.
- Chao AW, Bhati M, DuPont HL, Nataro J, Carlin L, Okhuysen P.. Clinical Features and Molecular Epidemiology of Diarrheagenic Escherichia coli Pathotypes Identified by Fecal Gastrointestinal Multiplex Nucleic Acid Amplification in Patients with Cancer and Diarrhea. Diagn Microbiol Infect Dis 89:235-240. e-Pub 2017.
- Chappell CL, Darkoh C, Shimmin L, Farhana N, Kim DK, Okhuysen PC, et al.. Fecal Indole as a Biomarker of Susceptibility to Cryptosporidium Infection. Infect Immun 84(8):2299-306, 2016.
- Ghosh N, Malik FA, Daver RG, Vanichanan J, Okhuysen PC.. Viral associated diarrhea in immunocompromised and cancer patients at a large comprehensive cancer center: a 10-year retrospective study. Infect Dis (Lond) 13:1-7, 2016.
- Darkoh C, Chappell C, Gonzales C, Okhuysen P. A Rapid and Specific Method for the Detection of Indole in Complex Biological Samples. Appl Environ Microbiol. e-Pub 2015. PMID: 26386049.
- Mocroft A, Lundgren JD, Ross M, Law M, Reiss P, Kirk O, Smith C, Wentworth D, Neuhaus J, Fux CA, Moranne O, Morlat P, Johnson MA, Ryom L, D:A:D study group, Royal Free Hospital Clinic Cohort, INSIGHT study group, SMART study group, ESPRIT study group. Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study. PLoS Med 12(3):e1001809, 2015. e-Pub 2015. PMID: 25826420.
- Chappell CL, Okhuysen PC, Langer-Curry RC, Lupo PJ, Widmer G, Tzipori S. Cryptosporidium muris: Infectivity and Illness in Healthy Adult Volunteers. Am J Trop Med Hyg, 2014.
- Mahale P, Okhuysen PC, Torres HA. Does chemotherapy cause viral relapse in cancer patients with hepatitis C infection successfully treated with antivirals?. Clin Gastroenterol Hepatol 12(6):1051-4, 2014.
- Nordell AD, McKenna M, Borges ÁH, Duprez D, Neuhaus J, Neaton JD; INSIGHT SMART, ESPRIT Study Groups; SILCAAT Scientific Committee. Severity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulation. J Am Heart Assoc 3(3), 2014. PMID: 24870935.
- Borges AH, O'Connor JL, Phillips AN, Baker JV, Vjecha MJ, Losso MH, Klinker H, Lopardo G, Williams I, Lundgren JD; INSIGHT SMART Study Group; ESPRIT Study Group; SILCAAT Scientific Committee. Factors associated with D-dimer levels in HIV-infected individuals. PLoS One 9(3), 2014. PMID: 24626096.
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- Bjerk SM, Baker JV, Emery S, Neuhaus J, Angus B, Gordin FM, Pett SL, Stephan C, Kunisaki KM; INSIGHT SMART Study Group. Biomarkers and bacterial pneumonia risk in patients with treated HIV infection: a case-control study. PLoS One 8(2):e56249, 2013. PMID: 23457535.
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- Flores-Figueroa J, Okhuysen PC, von Sonnenburg F, DuPont HL, Libman MD, Keystone JS, Hale DC, Burchard G, Han PV, Wilder-Smith A, Freedman DO, GeoSentinel Surveillance Network. Patterns of illness in travelers visiting Mexico and Central America: the GeoSentinel experience. Clin Infect Dis 53(6):523-31, 2011. e-Pub 2011. PMID: 21832261.
- Flores J, Dupont HL, Jiang ZD, Okhuysen PC, Melendez-Romero JH, Gonzalez-Estrada A, Carrillo I, Paredes M. A randomized, double-blind, pilot study of rifaximin 550 mg versus placebo in the prevention of travelers' diarrhea in Mexico during the dry season. J Travel Med 18(5):333-6, 2011. e-Pub 2011. PMID: 21896097.
- Chappell CL, Okhuysen PC, Langer-Curry RC, Akiyoshi DE, Widmer G, Tzipori S. Cryptosporidium meleagridis: infectivity in healthy adult volunteers. Am J Trop Med Hyg 85(2):238-42, 2011. PMID: 21813841.
- Cozzi-Lepri A, French MA, Baxter J, Okhuysen P, Plana M, Neuhaus J, Landay A, INSIGHT SMART study group. Resumption of HIV replication is associated with monocyte/macrophage derived cytokine and chemokine changes: results from a large international clinical trial. AIDS 25(9):1207-17, 2011. PMID: 21505304.
- Mohamed JA, DuPont HL, Flores J, Palur H, Nair P, Jiang ZD, Guo D, Belkind-Gerson J, Okhuysen PC. Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to Mexico. Clin Infect Dis 52(11):1332-41, 2011. PMID: 21596674.
- Paredes-Paredes M, Okhuysen PC, Flores J, Mohamed JA, Padda RS, Gonzalez-Estrada A, Haley CA, Carlin LG, Nair P, DuPont HL. Seasonality of diarrheagenic Escherichia coli pathotypes in the US students acquiring diarrhea in Mexico. J Travel Med 18(2):121-5, 2011. e-Pub 2011. PMID: 21366796.
- Villa NA, Okhuysen PC, Flores-Figueroa J, Jiang ZD, Belkind-Gerson J, Paredes M, Mohamed JA, Nair P, Carlin L, DuPont HL. Campylobacter jejuni is not an important pathogen as a cause of diarrhea in US travelers to Mexico. J Travel Med 18(1):56-8, 2011. e-Pub 2010. PMID: 21199144.
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- Flores J, DuPont HL, Paredes-Paredes M, Aguirre-Garcia MM, Rojas A, Gonzalez A, Okhuysen PC. Pilot study of whole-blood gamma interferon response to the Vibrio cholerae toxin B subunit and resistance to enterotoxigenic Escherichia coli-associated diarrhea. Clin Vaccine Immunol 17(5):879-81, 2010. e-Pub 2010. PMID: 20219880.
- Koo HL, Ajami NJ, Jiang ZD, Neill FH, Atmar RL, Ericsson CD, Okhuysen PC, Taylor DN, Bourgeois AL, Steffen R, DuPont HL. Noroviruses as a cause of diarrhea in travelers to Guatemala, India, and Mexico. J Clin Microbiol 48(5):1673-6, 2010. e-Pub 2010. PMID: 20305012.
- Martinez-Sandoval F, Ericsson CD, Jiang ZD, Okhuysen PC, Romero JH, Hernandez N, Forbes WP, Shaw A, Bortey E, DuPont HL. Prevention of travelers' diarrhea with rifaximin in US travelers to Mexico. J Travel Med 17(2):111-7, 2010. PMID: 20412178.
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- INSIGHT-SMART Study Group. Martinez E, Visnegarwala F, Grund B, Thomas A, Gibert C, Shlay J, Drummond F, Pearce D, Edwards S, Reiss P, El-Sadr W, Carr A. The effects of intermittent, CD4-guided antiretroviral therapy on body composition and metabolic parameters. AIDS 24(3):353-363, 2010.
- Flores J, Okhuysen PC. Genetics of susceptibility to infection with enteric pathogens. Curr Opin Infect Dis 22(5):471-6, 2009. PMID: 19633551.
- INSIGHT-ESPRIT Study Group. Abrams D, Levy Y, Losso MH, Babiker A, Collins G, Cooper DA, Darbyshire J, Emery S, Fox L, Gordin F, Lane HC, Lundgren JD, Mitsuyasu R, Neaton JD, Phillips A, Routy JP, Tambussi G, Wentworth D. Interleukin-2 therapy in patients with HIV infection. N Engl J Med 361(16):1548-1559, 2009.
- INSIGHT-SMART Study Group. Rodger AJ, Fox Z, Lundgren JD, Kuller LH, Boesecke C, Gey D, Skoutelis A, Goetz MB, Phillips AN. Activation and coagulation biomarkers are independent predictors of the development of opportunistic disease in patients with HIV infection. J Infect Dis 200(6):973-983, 2009.
- INSIGHT-SMART Study Group. Grund B, Peng G, Gibert CL, Hoy JF, Isaksson RL, Shlay JC, Martinez E, Reiss P, Visnegarwala F, Carr AD. Continuous antiretroviral therapy decreases bone mineral density. AIDS 23(12):1519-1529, 2009.
- Mohamed JA, DuPont HL, Jiang ZD, Flores J, Carlin LG, Belkind-Gerson J, Martinez-Sandoval FG, Guo D, White AC, Okhuysen PC. A single-nucleotide polymorphism in the gene encoding osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli, is associated with an increased risk of nonsecretory bacterial diarrhea in North American travelers to Mexico. J Infect Dis 199(4):477-85, 2009. PMID: 19128145.
- Flores J, Okhuysen PC. Enteroaggregative Escherichia coli infection. Curr Opin Gastroenterol 25(1):8-11, 2009. PMID: 19114769.
- INSIGHT-SMART Study Group. Mocroft A, Wyatt C, Szczech L, Neuhaus J, El-Sadr W, Tracy R, Kuller L, Shlipak M, Angus B, Klinker H, Ross M. Interruption of antiretroviral therapy is associated with increased plasma cystatin C. AIDS 23(1):71-82, 2009.
- Nallapareddy SR, Singh KV, Okhuysen PC, Murray BE. A functional collagen adhesin gene, acm, in clinical isolates of Enterococcus faecium correlates with the recent success of this emerging nosocomial pathogen. Infect Immun 76(9):4110-9, 2008. e-Pub 2008. PMID: 18591238.
- Flores J, DuPont HL, Lee SA, Belkind-Gerson J, Paredes M, Mohamed JA, Armitige LY, Guo DC, Okhuysen PC. Influence of host interleukin-10 polymorphisms on development of traveler's diarrhea due to heat-labile enterotoxin-producing Escherichia coli in travelers from the United States who are visiting Mexico. Clin Vaccine Immunol 15(8):1194-8, 2008. e-Pub 2008. PMID: 18579697.
- Nair P, Mohamed JA, DuPont HL, Figueroa JF, Carlin LG, Jiang ZD, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC. Epidemiology of cryptosporidiosis in North American travelers to Mexico. Am J Trop Med Hyg 79(2):210-4, 2008. PMID: 18689626.
- Grimes KA, Mohamed JA, Dupont HL, Padda RS, Jiang ZD, Flores J, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC. PCR-based assay using occult blood detection cards for detection of diarrheagenic Escherichia coli in specimens from U.S. travelers to Mexico with acute diarrhea. J Clin Microbiol 46(7):2227-30, 2008. e-Pub 2008. PMID: 18480224.
- Lupo PJ, Langer-Curry RC, Robinson M, Okhuysen PC, Chappell CL. Cryptosporidium muris in a Texas canine population. Am J Trop Med Hyg 78(6):917-21, 2008. PMID: 18541769.
- Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF, Okhuysen PC, Guerrero NH, Martinez-Sandoval FG, Meléndez-Romero JH, Jiang ZD, Asturias EJ, Halpern J, Torres OR, Hoffman AS, Villar CP, Kassem RN, Flyer DC, Andersen BH, Kazempour K, Breisch SA, Glenn GM. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet 371(9629):2019-25, 2008. PMID: 18554712.
- Flores J, DuPont HL, Jiang ZD, Belkind-Gerson J, Mohamed JA, Carlin LG, Padda RS, Paredes M, Martinez-Sandoval JF, Villa NA, Okhuysen PC. Enterotoxigenic Escherichia coli heat-labile toxin seroconversion in US travelers to Mexico. J Travel Med 15(3):156-61, 2008. PMID: 18494692.
- Huang DB, Brown EL, DuPont HL, Cerf J, Carlin L, Flores J, Belkind-Gerson J, Nataro JP, Okhuysen PC. Seroprevalence of the enteroaggregative Escherichia coli virulence factor dispersin among USA travellers to Cuernavaca, Mexico: a pilot study. J Med Microbiol 57(Pt 4):476-9, 2008. PMID: 18349368.
- Carr A, Grund B, Neuhaus J, El-Sadr WM, Grandits G, Gibert C, Prineas RJ and SMART study Investigators. Asymptomatic myocardial ischaemia in HIV-infected adults. AIDS(22):257-267, 2008.
- Strategies for Management of Antiretroviral Therapy Study Group. Emery S, Neuhaus JA, Phillips AN, Babiker A, Cohen CJ, Gatell JM, Girard PM, Grund B, Law M, Losso MH, Palfreeman A, Wood R. Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART study. J Infect Dis(197):1133-1144, 2008.
- SMART Study Group. El-Sadr WM, Grund B, Neuhaus J, Babiker A, Cohen CJ, Darbshire J, Emery S, Lundgren JD, Philips A, Neaton JD. Risk of Opportunistic Disease and Death after Re-initiating Continous Antiretroviral Therapy in Patients with HIV Previously Receiving Episodic therapy: A randomized Trial. Ann Intern Med(149):289-299, 2008.
- SMART Study Group. A, Cohen C, Neuhaus J, Baxter J, Emery S, Hirschel B, Hullsiek KH, Stephan C, Lundgren J Fox Z, Phillips. Viral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen. AIDS 12(22):2279-2289, 2008.
- Planque S, Mitsuda Y, Taguchi H, Salas M, Morris MK, Nishiyama Y, Kyle R, Okhuysen P, Escobar M, Hunter R, Sheppard HW, Hanson C, Paul S. Characterization of gp120 hydrolysis by IgA antibodies from humans without HIV infection. AIDS Res Hum Retroviruses 23(12):1541-54, 2007. PMID: 18160012.
- Huang DB, Mohamed JA, Nataro JP, DuPont HL, Jiang ZD, Okhuysen PC. Virulence characteristics and the molecular epidemiology of enteroaggregative Escherichia coli isolates from travellers to developing countries. J Med Microbiol 56(Pt 10):1386-92, 2007. PMID: 17893178.
- Ericsson CD, DuPont HL, Okhuysen PC, Jiang ZD, DuPont MW. Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin alone. J Travel Med 14(5):312-9, 2007. PMID: 17883462.
- Jiang ZD, Garey KW, Price M, Graham G, Okhuysen P, Dao-Tran T, LaRocco M, DuPont HL. Association of interleukin-8 polymorphism and immunoglobulin G anti-toxin A in patients with Clostridium difficile-associated diarrhea. Clin Gastroenterol Hepatol 5(8):964-8, 2007. e-Pub 2007. PMID: 17618838.
- Aguirre-García MM, Okhuysen PC. Cryptosporidium parvum: identification and characterization of an acid phosphatase. Parasitol Res 101(1):85-9, 2007. e-Pub 2007. PMID: 17252269.
- Mohamed JA, DuPont HL, Jiang ZD, Belkind-Gerson J, Figueroa JF, Armitige LY, Tsai A, Nair P, Martinez-Sandoval FJ, Guo DC, Hayes P, Okhuysen PC. A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to Mexico. Clin Infect Dis 44(7):945-52, 2007. e-Pub 2007. PMID: 17342646.
- Dupont HL, Jiang ZD, Belkind-Gerson J, Okhuysen PC, Ericsson CD, Ke S, Huang DB, Dupont MW, Adachi JA, De La Cabada FJ, Taylor DN, Jaini S, Martinez Sandoval F. Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone. Clin Gastroenterol Hepatol 5(4):451-6, 2007. e-Pub 2007. PMID: 17382603.
- Wang HC, Dann SM, Okhuysen PC, Lewis DE, Chappell CL, Adler DG, White AC. High levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity. Infect Immun 75(1):481-7, 2007. e-Pub 2006. PMID: 17043107.
- Mohamed JA, Huang DB, Jiang ZD, DuPont HL, Nataro JP, Belkind-Gerson J, Okhuysen PC. Association of putative enteroaggregative Escherichia coli virulence genes and biofilm production in isolates from travelers to developing countries. J Clin Microbiol 45(1):121-6, 2007. e-Pub 2006. PMID: 17093030.
- DuPont HL, Haake R, Taylor DN, Ericsson CD, Jiang ZD, Okhuysen PC, Steffen R. Rifaximin treatment of pathogen-negative travelers' diarrhea. J Travel Med 14(1):16-9, 2007. PMID: 17241249.
- The ESPRIT Research Group. Predictors of CD4 count change over 8 months of follow up in HIV-1-infected patients with a CD4 count>/=300 cells/muL who were assigned to 7.5 MIU interleukin-2. HIV Med(8):112-123, 2007.
- Chappell CL, Okhuysen PC, Langer-Curry R, Widmer G, Akiyoshi DE, Tanriverdi S, Tzipori S. Cryptosporidium hominis: experimental challenge of healthy adults. Am J Trop Med Hyg 75(5):851-7, 2006. PMID: 17123976.
- Huang DB, Mohanty A, DuPont HL, Okhuysen PC, Chiang T. A review of an emerging enteric pathogen: enteroaggregative Escherichia coli. J Med Microbiol 55(Pt 10):1303-11, 2006. PMID: 17005776.
- Huang DB, Nataro JP, DuPont HL, Kamat PP, Mhatre AD, Okhuysen PC, Chiang T. Enteroaggregative Escherichia coli is a cause of acute diarrheal illness: a meta-analysis. Clin Infect Dis 43(5):556-63, 2006. e-Pub 2006. PMID: 16886146.
- Ko G, Jiang ZD, Okhuysen PC, DuPont HL. Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to Noroviruses. J Med Virol 78(6):825-8, 2006. PMID: 16628572.
- Jiang ZD, DuPont HL, Garey K, Price M, Graham G, Okhuysen P, Dao-Tran T, LaRocco M. A common polymorphism in the interleukin 8 gene promoter is associated with Clostridium difficile diarrhea. Am J Gastroenterol 101(5):1112-6, 2006. PMID: 16573784.
- The Strategies for Management of Antiretroviral Therapy (SMART) Study Group. CD4+ Count-Guided Interruption of Antiretroviral Treatment. N. Engl J Med(355):2283-2296, 2006.
- Okhuysen PC. Current concepts in travelers' diarrhea: epidemiology, antimicrobial resistance and treatment. Curr Opin Infect Dis 18(6):522-6, 2005. PMID: 16258326.
- DuPont HL, Jiang ZD, Okhuysen PC, Ericsson CD, de la Cabada FJ, Ke S, DuPont MW, Martinez-Sandoval F. Antibacterial chemoprophylaxis in the prevention of traveler's diarrhea: evaluation of poorly absorbed oral rifaximin. Clin Infect Dis 41 Suppl 8:S571-6, 2005. PMID: 16267721.
- Ko G, Garcia C, Jiang ZD, Okhuysen PC, Belkind-Gerson J, Glass RI, DuPont HL. Noroviruses as a cause of traveler's diarrhea among students from the United States visiting Mexico. J Clin Microbiol 43(12):6126-9, 2005. PMID: 16333110.
- Mohr JF, McKinnon PS, Peymann PJ, Kenton I, Septimus E, Okhuysen PC. A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone. Pharmacotherapy 25(10):1303-9, 2005. PMID: 16185173.
- Okhuysen PC, Chappell CL, Lewis DE, Robinson P, White AC. Treatment of chronic cryptosporidiosis in AIDS with rIL-12 induces an immune response associated with improvement but severe side-effects. AIDS 19(12):1333-4, 2005. PMID: 16052094.
- DuPont HL, Jiang ZD, Okhuysen PC, Ericsson CD, de la Cabada FJ, Ke S, DuPont MW, Martinez-Sandoval F. A randomized, double-blind, placebo-controlled trial of rifaximin to prevent travelers' diarrhea. Ann Intern Med 142(10):805-12, 2005. PMID: 15897530.
- Kjos SA, Jenkins M, Okhuysen PC, Chappell CL. Evaluation of recombinant oocyst protein CP41 for detection of cryptosporidium-specific antibodies. Clin Diagn Lab Immunol 12(2):268-72, 2005. PMID: 15699421.
- Huang DB, Chappell C, Okhuysen PC. Cryptosporidiosis in children. Semin Pediatr Infect Dis 15(4):253-9, 2004. PMID: 15494949.
- Okhuysen PC, Jiang ZD, Carlin L, Forbes C, DuPont HL. Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico. Am J Gastroenterol 99(9):1774-1778, 2004. PMID: 15330917.
- Roberts JC, Singh KV, Okhuysen PC, Murray BE. Molecular epidemiology of the fsr locus and of gelatinase production among different subsets of Enterococcus faecalis isolates. J Clin Microbiol 42(5):2317-2320, 2004. PMID: 15131223.
- Huang DB, DuPont HL, Jiang ZD, Carlin L, Okhuysen PC. Interleukin-8 response in an intestinal HCT-8 cell line infected with enteroaggregative and enterotoxigenic Escherichia coli. Clin Diagn Lab Immunol 11(3):548-551, 2004. PMID: 15138180.
- Okhuysen PC, Rogers GA, Crisanti A, Spano F, Huang DB, Chappell CL, Tzipori S. Antibody response of healthy adults to recombinant thrombospondin-related adhesive protein of cryptosporidium 1 after experimental exposure to cryptosporidium oocysts. Clin Diagn Lab Immunol 11(2):235-238, 2004. PMID: 15013968.
- Huang DB, Okhuysen PC, Jiang ZD, DuPont HL. Enteroaggregative Escherichia coli: an emerging enteric pathogen. Am J Gastroenterol 99(2):383-389, 2004. PMID: 15046233.
- White AC, Robinson P, Okhuysen PC. Human studies provide insight into the pathogenesis, immunology, and treatment of cryptosporidiosis. Clin Infect Dis 37(7):989; author reply 989-90, 2003. PMID: 13130414.
- Jiang ZD, Okhuysen PC, Guo DC, He R, King TM, DuPont HL, Milewicz DM. Genetic susceptibility to enteroaggregative Escherichia coli diarrhea: polymorphism in the interleukin-8 promotor region. J Infect Dis 188(4):506-511, 2003. e-Pub 2003. PMID: 12898436.
- Robinson P, Okhuysen PC, Chappell CL, Weinstock JV, Lewis DE, Actor JK, White AC. Substance P expression correlates with severity of diarrhea in cryptosporidiosis. J Infect Dis 188(2):290-6, 2003. e-Pub 2003. PMID: 12854086.
- Alcantara CS, Yang CH, Steiner TS, Barrett LJ, Lima AA, Chappell CL, Okhuysen PC, White AC, Guerrant RL. Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis. Am J Trop Med Hyg 68(3):325-8, 2003. PMID: 12685639.
- Millership JJ, Chappell C, Okhuysen PC, Snowden KF. Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae. J Parasitol 88(5):843-848, 2002. PMID: 12435118.
- Chappell CL, Okhuysen PC. Cryptosporidiosis. Curr Opin Infect Dis 15(5):523-527, 2002. PMID: 12686887.
- Okhuysen PC, Chappell CL. Cryptosporidium virulence determinants--are we there yet?. Int J Parasitol 32(5):517-525, 2002. PMID: 11943224.
- Padda RS, Tsai A, Chappell CL, Okhuysen PC. Molecular cloning and analysis of the Cryptosporidium parvum aminopeptidase N gene. Int J Parasitol 32(2):187-97, 2002. PMID: 11812496.
- Teunis PF, Chappell CL, Okhuysen PC. Cryptosporidium dose response studies: variation between isolates. Risk Anal 22(1):175-183, 2002. PMID: 12017359.
- Okhuysen PC, Rich SM, Chappell CL, Grimes KA, Widmer G, Feng X, Tzipori S. Infectivity of a Cryptosporidium parvum isolate of cervine origin for healthy adults and interferon-gamma knockout mice. J Infect Dis 185(9):1320-1325, 2002. e-Pub 2002. PMID: 12001050.
- Teunis PF, Chappell CL, Okhuysen PC. Cryptosporidium dose-response studies: variation between hosts. Risk Anal 22(3):475-485, 2002. PMID: 12088227.
- Nannini EC, Okhuysen PC. HIV1 and the gut in the era of highly active antiretroviral therapy. Curr Gastroenterol Rep 4(5):392-398, 2002. PMID: 12228041.
- Millership JJ, Chappell CL, Okhuysen PC, Snowden KF. Characterization of a cytosolic aminopeptidase from Encephalitozoon intestinalis. Parasitology(124 Pt 1):1-7, 2002. PMID: 11811798.
- Robinson P, Okhuysen PC., Chappell CL., Lewis DE, Shahab I, Janecki A, White, AC, Jr. Expression of Tumor Necrosis Factor Alpha and Interleukin 1β in Jejuna of Volunteers after Experimental Challenge with Cryptosporidium parvum Correlates with Exposure but Not with Symptoms. Infect. Immun(69):1172-1174, 2001.
- Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Lahoti S, White AC Jr. Expression of Il-15 and Il-4 in INF-γ-Independent control of experimental human Cryptosporidium parvum infection. Cytokine(15):39-46, 2001.
- Okhuysen PC, Robinson P, Nguyen MT, Nannini EC, Lewis DE, Janecki A, Chappell CL, White AC Jr. Jejunal cytokine response in AIDS patients with chronic cryptosporidiosis and during immune reconstitution. AIDS(15):802-804, 2001.
- Messner MJ, Chappell CL, Okhuysen, PC. Risk Assessment for Cryptosporidium: A Hierarchical Bayesian Analysis of Human Dose Response Data. Water Research(35):3934-3940, 2001.
- Millership JJ, Didier ES, Okhuysen PC, Maddry JA, Kwong CD, Chen X, Snowden KF. In Vitro and in vivo Evaluation of aminopeptidase inhibitors as antimicrosporidial therapies. J. Eukariot Microbiol:95S-98S, 2001.
- Dasgupta, A. Okhuysen PC. Pharmacokinetic and other drug interactions in patients with AIDS. Ther Drug Monit(23):591-605, 2001.
- White AC, Robinson P, Okhuysen PC, Lewis DE, Shahab I, Lahoti S, DuPont HL, Chappell CL. Interferon-gamma Expression in Jejunal Biopsies in Experimental Human Cryptosporidiosis Correlates with Prior Sensitization and Control of Oocyst Excretion. J Infect Dis(181):701-709, 2000.
- Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Lahoti S, White, Jr, AC. TGF-β1 is expressed in the jejunum after experimental human Cryptosporidium parvum infection. Infect Immun(68):5405-5407, 2000.
- Dann MS, Okhuysen PC, DuPont HL, Chappell CL. Fecal antibody response to Cryptosporidium parvum in healthy volunteers. Infect and Immun(68):5068-5074, 2000.
- Chappell, CL, Okhuysen, PC, Sterling CR, Wang C, Jakubowski W, DuPont HL. Infectivity of Cryptosporidium parvum in Healthy Adults with Pre-Existing Anti-C. parvum IgG. Am. J. Trop. Med. Hyg(60):157-164, 1999.
- Okhuysen PC, Chappell CL, Crabb JH, Sterling CR, DuPont HL. Virulence of Three Distinct Cryptosporidium parvum Isolates for Healthy Adults. J Infect Dis(180):1275-1281, 1999.
- Okhuysen PC, DuPont HL, Chappell CL, Sterling CR, Jakubowski W. Susceptibility and serologic response of Healthy Adults to Reinfection With Cryptosporidium parvum. Infect Immun(66):441-443, 1998.
- Okhuysen PC, Chappell CL, Crabb J, Valdez LM, Douglass E, HL DuPont. Prophylactic Effect of Bovine Anti-Cryptosporidium Hyperimmune Colostrum Immunoglobulin in Healthy Volunteers Challenged with C. parvum. Clin Infect Dis(22):1324-1329, 1998.
- Moss DM, Lammie PJ, Chappell CL, Okhuysen PC, Hightower AW, Arrowood MJ, DuPont HL. The Antibody response to 27- 17-, and 15-kDa Cryptosporidium Antigens following Experimental Infection in Humans. J Infect Dis(178):827-833, 1998.
- Valdez LM, Schwab P, Okhuysen PC, Rakita RM. Paradoxical Subcutaneous Tuberculosis Abscess. Clin Infect Dis(24):734, 1997.
- Okhuysen PC. Onchocerciasis in an Expatriate Living in Cameroon. J Travel Medicine(4):11-13, 1997.
- Valdez LM, Hang D, Okhuysen PC, Chappell CL. Flow Cytometric Detection of Cryptosporidium Oocysts in Human Stool Samples. J Clin Microbiol(35):2013-2017, 1997.
- Chappell CL, Okhuysen PC, Sterling CS, DuPont HL. Cryptosporidium parvum: Intensity of Infection and Oocyst Excretion Patterns in Healthy Volunteers. J Infect Dis(173):232-236, 1996.
- Coque TM, Tomayko JF, Ricke SC, Okhuysen PC, Murray BE. Vancomycin Resistant Enterococci from Nosocomial, Community and Animal Sources in the Unites States. Antimicrobial Agents and Chemotherapy(40):2605-2609, 1996.
- Okhuysen PC, Chappell CL, Kettner C, Sterling CR. Cryptosporidium parvum Metalloaminopeptidase Inhibitors Prevent in Vitro Excystation. Antimicrobial Agents and Chemotherapy(40):2781-2784, 1996.
- Okhuysen PC, Jiang X, Yee L, Johnson PC, Estes MK. Viral Shedding and Fecal IgA Response after Norwalk Virus Infection. J Infect Dis(171):566-569, 1995.
- DuPont HL, Chappell CL, Sterling CR, Okhuysen PC, Rose J, Jakubowski W. The Infectivity of Cryptosporidium parvum for Adult Humans. N. Engl. J. Med(322):855-859, 1995.
- Okhuysen PC, DuPont HL, Ericsson CD, Marani S, Martinez-Sandoval FG, Olesen MA, Ravelli GP. Zaldaride Maleate, a New Calmodulin Antagonist Versus Loperamide in the Treatment of Travelers' Diarrhea, a Placebo Controlled Trial. Clin Infect Dis(21):341-344, 1995.
- Okhuysen PC, Rex J, Fife C, Kapusta M.. Successful Treatment of Renal and Soft Tissue Apophysomyces elegans Infection in a Normal Host. Clin Infect Dis(29):329-331, 1994.
- Scerpella E, Okhuysen PC, Mathewson JJ, Guerrant RL, Latimer E, Lyerly D, Ericsson CD. Utility of a Rapid Latex Agglutination Test for Lactoferrin for Predicting Infection Due to Invasive Enteropathogens. J Travel Med(3):68-71, 1994.
- Okhuysen PC, DuPont HL, Sterling CR, Chappell CL. Arginine Aminopeptidase, an Integral Membrane Protein of the Cryptosporidium parvum Sporozoite. Infect Immun(62):4667-4670, 1994.
- Okhuysen PC, Singh KV, Murray BE. Susceptibility of Beta-Lactamase Producing Enterococci to Piperacillin/Tazobactam. Diagn Micro and Infect Dis(17):219-224, 1993.
- Okhuysen PC, Flores F, DuPont HL, Flores-Lopez JJ, Mathewson JJ, Perez-Castell F. A Comparative Study of Furazolidone and Placebo in Addition to Oral Rehydration Therapy in the Treatment of Infantile Gastroenteritis. Scan J Gastroentrol(24s):39-46, 1989.
- Gudiol C, Hicklen RS, Okhyusen PC, Malek AE, Kontoyiannis DP. Infections simulating immune checkpoint inhibitor toxicities: Uncommon and deceptive. Open Forum Infectious Diseases.
- EA Yepez-Guevara, Francisco DM, Aitken SL, Olvera AV, Carlin L, Fernandes K, Wang Y, Shelburne S, Jenq RR, Garey K, Dillon R, Obi EN, Adachi JA, Okhuysen PC. Fecal markers of inflammation and burden of Clostridioides difficile infection in cancer and immunocompromised patients. Clin Infect Dis.
Invited Articles
- Flores J, Okhuysen PC. Enteroaggregative Escherichia coli infection. Curr Opin Gastroenterol 25(1):8-11, 2009. PMID: 19114769.
- Flores J, Okhuysen PC. Genetics of susceptibility to infection with enteric pathogens. Curr Opin Infect Dis 22(5):471-476, 2009.
- Okhuysen, PC. Travelers’ Diarrhea. New insights. J Clin Gastroenterol, 2007.
- Okhuysen PC. Current concepts in travelers' diarrhea: epidemiology, antimicrobial resistance and treatment. Curr Opin Infect Dis 18(6):522-526, 2005.
- Huang DB, Chappell C, Okhuysen PC. Cryptosporidiosis in children. Semin Pediatr Infect Dis 15(4):253-259, 2004.
- Okhuysen, PC. Chappell CL. Virulence determinants in Cryptosporidium. Are we there yet?. Int J Parasitol(32):517-525, 2002.
- Chappell CL, Okhuysen PC. Cryptosporidiosis. Current Opinion in Infectious Diseases(15):253-259, 2002.
- Okhuysen, PC. Traveler’s diarrhea due to Intestinal Protozoa. Clin Inf Dis(33):110-114, 2001.
- 4. Okhuysen PC, White AC Jr. Related Articles, Parasitic infections of the intestines. Curr Opin Infect Dis 12(5):467-472, 1999.
- Okhuysen PC, Ericsson CD. Travelers' Diarrhea. Current Concepts in Gastroenterology(9):103-106, 1993.
- Okhuysen PC, Ericsson CD. Travelers' Diarrhea. Current Concepts in Gastroenterology(8):110-114, 1992.
- Okhuysen PC, Ericsson CD. Travelers' Diarrhea. Prevention and Treatment. Med Clin N Am(6):1357-1373, 1992.
Professional Educational Materials
- . Improving Management and Optimizing Treatment for the HIV Positive Population. Mediimax Communications, 2004.
- . Consultant to Rice University - MedMyst - Malaria interactive software (An NIH/CDC funded Science Education Partnership Award SEPA), 2004.
Abstracts
- Abu-Sbeih H, Irshad Q, Wang X, Okhuysen PC, Lum P, Shuttlesworth G, Stroehlein J, Wang Y. Multiple recurrent Clostridium difficine infection is associated with treatment failure and prolonged illness in cancer patients. Programs and abstracts of the 2018 Digestive Diseases Week, June 4, 2018, Chicago, IL, 2018.
- E. Yepez Guevara, H. Yalamanchili, A. Chao, K. Garey, M. Bhatti, S.. Relevance of Clostridium difficile ribotype 014-20 in cancer patients with diarrhea. Program and Abstracts of the 28th European Congress on Clinical Microbiology and Infectious Diseases, Madrid, Spain, April 16-18, 2018. e-Pub 2018.
- Wang W, Okhuysen PC. Yersinia enterocolitica infections in Cancer Patients: A Case Series. Program and Abstracts IDWeek, San Francisco, CA, October 2-17, 2018, 2018.
- Okhuysen P, Olvera A,. Characterization of enteropathogenic Escherichia coli (EPEC) in cancer patients with diarrhea. Program and Abstracts IDWeek, San Francisco, CA, October 2-7, 2018, 2018.
- Yepez E, Yalamanchili H, Chao A, Garey K, Bhatti M, Aitken S, Okhuysen P. Ribotypes matter. Significance of Clostridium difficile ribotypes in Cancer patients with diarrhea. Program and Abstracts IDWeek 2017, Abstract 1265. October 4-8, San Diego, CA, 2017.
- Chao A, Yalamanchili H, Yepez E, Bhatti M, Aitken S, Okhuysen PC. Line of Service-Specific Performance and Antibiotic Prescription Habits following Introduction of a Two Step Diagnostic Approach using NAAT Followed by Enzyme Immunoassay in Cancer Patietns with Suspected Clostridium difficile Infection. Program and Abstracts IDWeek 2017, Abstract 1286. October 4-8, San Diego, CA, 2017.
- Yalamanchili H, Chao A, Yepez E, Aitken S, Bhatti M, Okhuysen PC. Risk Factors and Clinical Outcomes of Cancer Patients with Clostridium difficile Associated Diarrhea Co-infected with a second pathogen. Program and Abstracts IDWeek 2017, Abstract 1185. October 4-8, San Diego, CA, 2017.
- Chao A, Bhatti M, Carlin L, Okhuysen PC. Clinical characteristics and molecular epidemiology of diarrhoeagenic Escherichia coli in cancer patients. Program and Abstracts European Congress of Clinical Microbiology and Infectious Diseases 2017, Vienna, Austria, 2017.
- Farida Malik, MD, Natasha Ghosh, MPH, Pablo Okhuysen, MD, FIDSA, Roshni Daver, MBBS, MD, Jakapat Vanichanan, MD, Lily Carlin, BS. Clinical and Epidemiological Characteristics of Viral Associated Diarrhea (VAD) in Immunocompromised and Cancer Patients at MD Anderson Cancer Center (MDACC) 2005-2014. Programs and Abstracts ID Week 2016(1215), 2016.
- Malik FA, Okhuysen PC, Alousi A, Shpall EJ, Shelburne SA, Petrosino JF, Rezvani K, Ajami NJ, Ghosh N, Carlin LG, Chemaly RF. Fecal Indole Correlates With Loss of Microbiome Diversity in Hematopoietic Stem Cell Transplant (HSCT) Recipients With and Without Intestinal Graft Versus Host Disease (iGVHD). Programs and Abstracts of the Infectious Diseases Society of America Annual Meeting, Presentation 700, Session 116, San Diego CA, 2015.
- Daver RG, Shewale J, Lindsay B, Oundo J, Ochieng B, Saha D, Breimen R, Antonio M, Panchalingam S, Volcik K, Grove-Gaona M, Stine OC, Nataro JP, Kaper J, Levine MM, Kotloff KL, Okhuysen PC. Host Gene Polymorphisms and Susceptibility to Bacterial Enteropathogens in Children Living in Gambia and Kenya. Programs and Abstracts of the American Society for Tropical Medicine and Hygiene 63rd annual meeting, New Orleans LA, 2014.
- Daver RG, Shewale J, Lindsay B, Oundo J, Ochieng B, Saha D, Breimen R, Antonio M, Panchalingam S, Volcik K, Grove-Gaona M, Stine OC, Nataro JP, Kaper J, Levine MM, Kotloff KL, Okhuysen PC. Host Gene Polymorphisms and Susceptibility to Viral Enteropathogens in Children Living in The Gambia and Kenya. ID Week Programs and Abstracts of the Infectious Diseases Society of America Annual Meeting, Philadelphia PA, 2014.
- DuPont HL, Okhuysen PC, Chappell CL. Controlled Human Infection Studies in the Development of Vaccines and Therapeutics. The Wellcome Trust, 2013.
- Okhuysen PC, Lewis DE, Carlin LG, Orozco AF, Gomez DM, Raynor MJ, Jiang ZD and DuPont HL. Analysis of diffusely adhering Escherichia coli (DAEC) and enteroaggregative E. coli (EAEC) adherence to HEp-2 cells by flow cytometry reveals distinct patterns of attachment and cell death caused by isolates from visitors to Mexico and India with travelers’ diarrhea. 49th Infectious Diseases Society of America Annual Meeting, Boston MA, 2011.
- Cozzi-Lepri A, French M, Baxter J, Okhuysen PC, Plana M, Nehaus J, Landay, A. Resumption of HIV replication in SMART Study patients is associated with monocyte/macrophage derived cytokine and chemokine changes in addition to CD4+ T cell decline. Conference on Retrovirus and Opportunistic Infections (CROI), Boston MA, 2011.
- Flores J, Gonzalez-Estrada A, DuPont HL, Paredes-Paredes M, Mohamed JA, Carlin L, Okhuysen PC. Dispersin Expression by Non-Enteroaggregative Escherichia coli Isolated from US Travelers with Acute Diarrhea Visiting Mexico. Programs and Abstracts of the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Philadelphia PA, 2009.
- Flores J, Okhuysen PC, Belkind-Gerson J, Gonzalez-Estrada A, Paredes-Paredes M, Mohamed JA, Carlin L, Haley CA, DuPont HL. Incidence of Diarrheagenic Escherichia coli in US Travelers with Acute Diarrhea Visiting Mexico; Emergence of Enteropathogenic E. coli (EPEC) and Enterohemorrhagic E. coli (EHEC) as Causal Agents. Programs and Abstracts of the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Philadelphia PA, 2009.
- Flores J, DuPont HL, Belkind-Gerson J, Paredes M, Aguirre M, Rojas A, Okhuysen PC. Whole Blood Gamma Interferon Response to Cholera Toxin B and Resistance to Travelers’ Diarrhea. A Pilot Study of Cellular Immunity and ETEC Diarrhea (Poster 1615). Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC (Poster 1615), 2008.
- Haley CC, DuPont HL, Paredes M, Flores J, Mohamed JA, Belkind-Gerson J, Jiang ZD, Gonzalez A, Martinez Sandoval FG, Okhuysen PC. Prevalence of STEC Associated Diarrhea in US travelers to Mexico. Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC, 2008.
- Paredes M, DuPont HL, Belkind-Gerson J, Flores J, Carlin L, Mohamed JA, Gonzalez-Estrada A, Nair P, Okhuysen PC. Seasonal Influence on the Occurrence of Traveler’s Diarrhea due to Diarrheagenic E. coli. Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC (Poster 1613), 2008.
- Okhuysen PC, Flores J, Mohamed JA, J Belkind-Gerson, Jiang ZD, Nair P, FG Martinez Sandoval FG and DuPont HL. Gene Polymorphisms in Molecules involved in the innate immune response to Lipopolysaccharide (LPS) Predispose to Diarrhea in US Travelers to Mexico. Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC, 2008.
- Mohamed JA, DuPont HL, Jiang ZD, Tsai A, Flores J, Belkind-Gerson J, Martinez Sandoval FG, Guo DC, Okhuysen PC. A single nucleotide Polymorphism in the Osteoprotegerin Gene is associated with Traveler’s Diarrhea. Programs and Abstracts of the 45th Infectious Diseases Society of America Annual Meeting, San Diego CA, 2007.
- Nair P, DuPont HL, Mohamed JA, Flores J, Jiang ZD, Belkind-Gerson J, Martinez-Sandoval F, Okhuysen Nair P, HL DuPont, JA Mohamed, J Flores, ZD Jiang, J Belkind-Gerson, F Martinez-Sandoval, Okhuysen PC. Epidemiology of Cryptosporidiosis in North American Travelers to Mexico. Program and Abstracts of the 45th Infectious Diseases Society of America Annual Meeting, San Diego CA, 2007.
- Flores J, DuPont HL, Jiang ZD, Belkind-Gerson J, Tsai A, Mohamed JA, Martinez-Sandoval FG, Guo DC, Okhuysen PC. Influence of Host IL-10 Polymorphism on the Development of Traveler’s Diarrhea. Program and Abstracts of the 45th Infectious Diseases Society of America Annual Meeting, San Diego CA, 2007.
Book Chapters
- Malek A and Okhuysen PC. Infectious Diseases. In: Managing Immunotherapy Related Organ Toxicities. 1. Springer Nature Switzerland AG: Cham, Switzerland, 2022.
- DuPont, HL, Okhuysen PC. Shigella and enteroinvasive E. coli. In: Principles and Practice of Infectious Diseases. Ninth. Elsevier: Philadelphia Pennsylvania, 2019.
- Rex, J and Okhuysen PC. Sporotrichosis. In: Principles and Practice of Infectious Diseases. Ninth. Elsevier: Philadelphia, 2019.
- DuPont HL and Okhuysen PC. Approach to the Patient with Suspected Enteric Infection. In: Goldman and Cecil Medicine. 26th. Elsevier: Philadelphia, 2019.
- Rex JH, Okhuysen PC. Sporotrichosis. In: Principles and Practice of Infectious Diseases, Eighth Edition. Eight Edition. Churchill Livingstone: New York, 2014.
- Rex JH, Okhuysen PC. Sporotrichosis. In: Principles and Practice of Infectious Diseases, Seventh Edition. Seventh. Churchill Livingstone: New York, 2009.
- Okhuysen PC, Lee SA, Guerrant RL. Genetic Susceptibility to Enteric Infections; Implications for Endemic and Travelers’ Diarrhea. In: Travelers’ Diarrhea Textbook, 2nd Edition. 2nd. Becker: Lewinston NY, 153-158, 2007.
- Petry WA, Snider C, Okhuysen PC. The parasitic pathogens. In: Travelers’ Diarrhea Textbook. 2nd edition. 2nd. Becker: Lewinston NY, 31-42, 2007.
- Rex JH, Okhuysen PC. Sporotrichosis. In: Principles and Practice of Infectious Diseases, Sixth Edition. Sixth. Churchill Livingstone: New York, 2984-2988, 2005.
- Mead JR, Okhuysen PC. Rationale approaches to treating Cryptosporidium, Cyclospora, Giardia and Entamoeba. In: World Class Parasites: Volume 8. Kluwer Academic: Norwell MA, 2004.
- Okhuysen PC, White AC. Parasites. In: Traveler’s Diarrhea. Becker: Lewinston NY, 47-57, 2003.
- Chappell, CL, Okhuysen PC. Cryptosporidiosis. In: North American Parasitic Zoonoses. Kluwer Academic: Norwell MA, 113-128, 2002.
- Ostrosky L, Okhuysen PC. Acute Infectious Diarrhea. In: Conn’s Current Therapy. Sauders WB, 12-18, 2001.
- Chappell CL, Okhuysen PC. Cryptosporidiosis in Healthy Volunteers. In: Cryptosporidium: The Analytical Challenge. Royal Society of Chemistry: London, 62-72, 2001.
- Okhuysen PC. Chappell CL. Intestinal Protozoa. In: Textbook of Internal Medicine, Fourth Edition. Fourth. Lippincott Raven: New York, 2000.
- Okhuysen PC. Central and Mainland America. In: Textbook of Travel Medicine, Second edition, 67, 2000.
- Rex JR, Okhuysen PC. Sporotrichosis. In: Principles and Practice of Infectious Diseases. Fifth. Churchill Livingston: New York, 2695-2698, 1999.
- Marshall GD, Okhuysen PC. HIV Infection: Diagnosis and Early Management. In: Current Practice of Medicine. Current Medicine: Phillip, PA, 1999.
- Okhuysen PC, Chappell, CL. Intestinal Protozoa. In: Textbook of Internal Medicine, Third Edition. Third. Lippincott Raven: New York, 1791-1794, 1997.
Letters to the Editor
- Cabada MM, Okhuysen PC, White AC Jr. Enteropathogens and chronic illness in returning travelers. N Engl J Med 369: 783, 2013.
- Okhuysen PC, Crane JK, Pappas J. St. Louis Encephalitis in Patients With Human Immunodeficiency Virus Infection. Clin Infect Dis: 140-141, 1993.
Patient Reviews
CV information above last modified February 02, 2023