Meet Patrick Lin, M.D.
Patrick P. Lin, M.D.
Department of Orthopaedic Oncology, Division of Surgery
About Dr. Lin
Dr. Patrick Lin is a Professor in the Department of Orthopaedic Oncology at The University of Texas MD Anderson Cancer Center in Houston, Texas. He specializes in the field of limb salvage through basic and clinical research in sarcomas and tumors involving connective tissue. Dr. Lin’s research addresses both the fundamental biology of tumors as well as the biomechanical challenges of restoring large skeletal defects. He has published more than 100 manuscripts in peer-reviewed journals and has edited two textbooks. Dr. Lin has received multiple grants for sarcoma-related research and has presented at numerous conferences and symposiums.
Present Title & Affiliation
Primary Appointment
Professor, Department of Orthopedic Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Clinical Professor, Department of Orthopaedic Surgery, University of Texas - Houston Health Science Center, Houston, TX
Clinical Assistant Professor, Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX
Education & Training
Degree-Granting Education
1990 | Stanford University School of Medicine, Stanford, CA, USA, MD, Medicine |
1984 | Harvard University, Cambridge, MA, USA, BA, Biochemical Sciences |
Postgraduate Training
1996-1998 | Clinical Fellowship, Orthopaedic Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY |
1991-1996 | Clinical Residency, Orthopaedic Surgery, University of North Carolina Hospitals, Chapel Hill, NC |
1990-1991 | Clinical Internship, General Surgery, University of North Carolina Hospitals, Chapel Hill, NC |
Board Certifications
2001 | American Board of Orthopaedic Surgery |
Experience & Service
Academic Appointments
Associate Professor, Department of Orthopedic Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, 2004 - 2015
Assistant Professor, Department of Orthopedic Oncology, Division of Surgery, University of Texas M.D. Anderson Cancer Center, Houston, TX, 1998 - 2004
Administrative Appointments/Responsibilities
Director of Research, Department of Surgical Oncology, Section of Orthopaedic Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 2001 - Present
Director of Physician Assistants and Nurse Practitioners, Department of Surgical Oncology, Section of Orthopaedic Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX, 2000 - 2001
Designer and Manager of Internet Web Page, Department of Surgical Oncology, Section of Orthopaedic Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX, 1999 - 2001
Other Appointments/Responsibilities
Volunteer Faculty Member, University of Texas-Houston Health Science Center, Houston, TX, 2002 - Present
Instructor, University of North Carolina School of Medicine, Chapel Hill, NC, 1992 - 1992
Institutional Committee Activities
Member, Minimally Invasive and New Technologies in Oncologic Surgery (MINTOS), 2023 - Present
Member, Division of Surgery Basic & Translational Research Committee, 2019 - Present
Member, Division of Surgery Promotion and Tenure Committee, 2016 - Present
Member, Pelvic Sarcoma Center of Excellence Committee, 2016 - 2018
Member, Clinical Competency Committee of the Musculoskeletal Oncology Fellowship, 2014 - Present
Member, Chondrosarcoma Workgroup, 2012 - Present
Member, Synovial Sarcoma Workgroup, 2012 - Present
Member, Osteosarcoma/Ewing Sarcoma Workgroup, 2012 - Present
Member, Study Section Review Committee for the Sister Institution Network Funding Program, 2011 - 2016
Member, Safety Committee, Perioperative Enterprise, 2010 - 2017
Member, Value Analysis Team, Perioperative Enterprise, 2008 - Present
Member, Clinical Research Committee I, 2005 - 2007
Member, Clinical Research Committee II, 2004 - 2005
Member, Briscoe PA Award Committee, 2003 - 2003
Alternate Member, Operating Room Committee, 2003 - 2006
Honors & Awards
2020 | Outstanding Author Award, Chinese Clinical Oncology |
2016 | Surgeon Educator of the Year Award, MD Anderson Cancer Center Perioperative Nurse Residency Program |
2013 | Top Doctor, Southeast Texas, Castle Connolly |
2013 | Best Doctor, Orthopedic Surgery, Best Doctors |
2012 | U.S. News Top Orthopedic Surgeon, U.S. News & World Report |
2011 | Best Doctor, Orthopedic Surgery, Best Doctors |
2008 | Top Doctor, Castle Connolly |
1996 | American Orthopaedic Association-Zimmer Resident Research Award |
1987 | Radiation Research Society Student Travel |
1983 | Phi Beta Kappa |
1981 | Harvard Detur Prize |
1980 | National Merit Scholarship |
1980 | High School Valedictorian |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Hirase T, Rowan C, Jacob T, Vemu SM, Aflatooni JO, Patel SS, Satcher RL, Lin PP, Moon BS, Lewis VO, Marco RAW, Bird JE. Percutaneous cementation for improvement of pain and function for osteolytic pelvic metastasis: A systematic review. J Am Acad Orthop Surg 32(14):e726-e736, 2024.
- Roland CL, Nassif Haddad EF, Keung EZ, Wang WL, Lin PP, et al. A randomized, non-comparative phase 2 study of neoadjuvant immune-checkpoint blockade in retroperitoneal dedifferentiated liposarcoma and extremity/truncal undifferentiated pleomorphic sarcoma. Nat Cancer 5(4):625-641, 2024. PMID: 38351182.
- Mueller MA, Mericli AF, Roubaud MS, Liu J, Adelman D, Lewis VO, Lin PP, Hanasono MM. Comparing fibula flap insetting techniques for pediatric oncologic extremity reconstruction. Plast Reconstr Surg 153(3):636e-643e, 2024. PMID: 37166051.
- Johnson JD, Satcher RL, Feng L, Lewis VO, Moon BS, Bird JE, Lin PP. What is the prosthetic survival after resection and intercalary endoprosthetic reconstruction for diaphyseal bone metastases of the humerus and femur?. Clin Orthop Relat Res 481(11):2200-2210, 2023. PMID: 37185204.
- Roubaud MS, Hassan AM, Shin A, Mericli AF, Adelman DM, Hagan K, Popat K, Lin P, Moon B, Lewis VO. Outcomes of targeted muscle reinnervation and regenerative peripheral nerve interfaces for chronic pain control in the oncologic amputee population. J Am Coll Surg 237(4):644-654, 2023.
- Vemu SM, Al Farii H, Bird JE, Lin PP, Lewis VO, Patel SS. The use of photodynamic bone stabilization to tamponade bleeding in a pathologic humeral shaft fracture: A case report. J Orthop Case Rep 13(9):137-143, 2023. PMID: 37753123.
- Pourebrahim R, Heinz Montoya R, Alaniz Z, Ostermann L, Lin PP, Liu B, Ayoub E, Burks JK, Andreeff M. Mdm2/p53 levels in bone marrow mesenchymal stromal cells are essential for maintaining the hematopoietic niche in response to DNA damage. Cell Death Dis 14(6):371, 2023. PMID: 37353528.
- Witt RG, Voss RK, Chiang YJ, Nguyen S, Scally CP, Lin PP, Torres KE, Moon BS, Satcher RL, Hunt KK, Bird JE, Feig BW, Lewis VO, Roland CL, Keung EZ. Practice pattern variability in the management of regional lymph node metastasis in extremity and trunk soft tissue sarcoma (ETSTS): A survey of the Society of Surgical Oncology (SSO) and Musculoskeletal Tumor Society (MSTS) Membership. Ann Surg Oncol 30(6):3668-3676, 2023. PMID: 36723723.
- Mericli AF, Asaad M, Lewis VO, Lin PP, Goodenough CJ, Adelman DM, Oates SD, Hanasono MM. Free fibula flap for extremity oncologic defects: Factors influencing union and functional outcomes. Plast Reconstr Surg 151(4):885-896, 2023. PMID: 36729822.
- Guadagnolo BA, Bassett RL, Mitra D, Farooqi A, Hempel C, Dorber C, Willis T, Wang WL, Ratan R, Somaiah N, Benjamin RS, Torres KE, Hunt KK, Scally CP, Keung EZ, Satcher RL, Bird JE, Lin PP, Moon BS, Lewis VO, Roland CL, Bishop AJ. Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open label, single-arm, phase 2 trial. Lancet Oncol 23(12):1547-57, 2022.
- Li B, Li G, Yan X, Zhu D, Lin PP, Wang Z, Qu H, He X, Fu Y, Zhu X, Lin P, Zhang J, Li X, Dai H, Chen H, Poznansky MC, Lin N, Ye Z. Fresh tissue multi-omics profiling reveals immune classification and suggests immunotherapy candidates for conventional chondrosarcoma. Clin Cancer Res 27(23):6543-6558, 2021. PMID: 34426437.
- El Beaino M, Wang W-L, Alaraj SF, Gugala Z, Lin PP. Osteofibrous dysplasia and adamantinoma: A summary of diagnostic challenges and surgical techniques. Surg Oncol 38:101626, 2021. PMID: 34280695.
- Patel RR, Lupo PJ, Bishop AJ, Lin PP, Delclos GL, Lazar AJ, Benjamin RS, Araujo DM. Synovial sarcoma of the hand and foot: An institutional review. Am J Clin Oncol 44(7):361-368, 2021. PMID: 33927134.
- Costelloe CM, Lin PP, Chuang HH, Amini B, Chainitikun S, Yu TK, Ueno NT, Murphy Jr, WA, Madewell JE. Bone metastases: Mechanisms of the metastatic process, imaging and therapy. Semin Utrasound CT and MRI 42(2):164-183, 2021. PMID: 33814103.
- Boyce-Fappiano D, Guadagnolo BA, Ratan R, Wang WL, Wagner MJ, Patel S, Livingston JA, Lin PP, Diao K, Mitra D, Farooqi A, Lazar AJ, Roland CL, Bishop AJ. Evaluating the soft tissue sarcoma paradigm for the local management of extraskeletal Ewing sarcoma. The Oncologist 26(3):250-260, 2021. PMID: 33289298.
- Liu J, Fan Z, El Beaino M, Lewis VO, Moon BS, Satcher RL, Bird JE, Frink SJ, Lin PP. Surgical drainage after limb salvage surgery and endoprosthetic reconstruction: is 30 mL/day critical?. J Orthop Surg Res 16(1):137, 2021. PMID: 33588915.
- Flint JH, Conley AP, Rubin ML, Feng L, Lin PP, Moon B, Bird J, Satcher RL, Lewis VO. Clear cell chondrosarcoma: Clinical characteristics and outcomes in 15 patients. Sarcoma 2020:6 pages, 2020.
- El Beaino M, Rassy E, Hadid B, Araujo DM, Pavlidis N, Lin PP. Synovial sarcoma: A complex disease with multifaceted signaling and epigenetic landscapes. Current Oncol Rep 22(12):124, 2020. PMID: 33025259.
- Nemir S, Mericli AF, Adelman DM, Liu J, Feig BW, Lin PP, Roubaud MS. A reconstructive algorithm of oncologic defects of the upper trunk and shoulder girdle: Factors predicting complexity and outcomes. J Surg Oncol 122(2):283-292, 2020. PMID: 32363601.
- El Beaino M, Jupiter DC, Assi T, El Rassy E, Lazar A, Araujo D, Lin P. Diagnostic value of TLE1 in synovial sarcoma: A systematic review and meta-analysis. Sarcoma 2020:6 pages, 2020. PMID: 32322158.
- El Beaino M, Liu J, Wasylishen AR, Pourebrahim R, Migut A, Bessellieu BJ, Huang K, Lin PP. Loss of Stag2 cooperates with EWS-FLI1 to transform murine mesenchymal stem cells. BMC Cancer 20:Article Number 3, 2020. PMID: 31898537.
- Heng M, Gupta A, Bishop A, Chung PW, Healey JH, Vaynrub M, Rose PS, Houdek MT, Lin PP, Bishop AJ, Hornicek FJ, Chen YL, Lozano-Calderon S, Holt GE, Han I, Biau D, Niu X, Bernthal NM, Ferguson PC, Wunder JS, Japanese Musculoskeletal Oncology Group (JMOG), Soft Tissue Osteosarcoma International Collaborative (STOICl. The role of chemotherapy and radiotherapy in localized extraskeletal osteosarcoma. Eur J Cancer 125:130-141, 2020. PMID: 31806415.
- Bishop AJ, Bird JE, Conley AP, Roland CL, Moon BS, Satcher RL, Livingston JA, Patel S, Wang WL, Lazar AJ, Lewis VO, Lin PP, Guadagnolo BA. Extraskeletal myxoid chondrosarcomas: Combined modality therapy with both radiation and surgery improves local control. Am J Clin Oncol 42(10):744-748, 2019. PMID: 31436747.
- Xue R, Lewis VO, Moon BS, Lin PP. Local recurrence of Ewing sarcoma: Is wide excision acceptable treatment?. J Surg Oncol 120(4):746-752, 2019. PMID: 31286523.
- Nguyen QN, Chun SG, Chow E, Komaki R, Liao Z, Zacharia R, Szeto BK, Welsh JW, Hahn SM, Fuller CD, Moon BS, Bird JE, Satcher R, Lin PP, Jeter M, O'Reilly MS, Lewis VO. Single-Fraction stereotactic vs. conventional multifraction radiotherapy for pain relief in patients with predominantly nonspine bone metastases: A randomized phase 2 trial. JAMA Oncol 5(6):872-878, 2019. PMID: 3102139.
- Wallace MT, Lin PP, Bird JE, Moon BS, Satcher RL, Lewis VO. The accuracy and clinical utility of intraoperative frozen section analysis in open biopsy of bone. J Am Acad Orthop Surg 27(11):410-417, 2019. PMID: 30379758.
- El Beaino M, Liu J, Lewis VO, Lin PP. Do early results of proximal humeral allograft-prosthetic composite reconstructions persist at 5-year followup?. Clin Orthop Relat Res 477(4):758-765, 2019. PMID: 30811366.
- El Beaino M, Liu J, Lin PP. Modular endoprosthetic implant for maximizing residual limb length: A case report. Prosthet Orthot Int 43(1):123-126, 2019. PMID: 30319024.
- Chafey DH, Lewis VO, Satcher RL, Moon BS, Lin PP. Is a cephalomedullary nail durable treatment for patients with metastatic peritrochanteric disease?. Clin Orthop Relat Res 476(12):2392-2401, 2018. PMID: 30299285.
- Pan T, Lin SC, Yu KJ, Yu G, Song JH, Lewis VO, Bird JE, Moon B, Lin PP, Tannir NM, Jonasch E, Wood CG, Gallick GE, Yu-Lee LY, Lin SH, Satcher RL. BIGH3 promotes osteolytic lesions in renal cell carcinoma bone metastasis by inhibiting osteoblast differentiation. Neoplasia 20(1):32-43, 2018.
- Pourebrahim R, Zhang Y, Liu B, Gao R, Xiong S, Lin PP, McArthur MJ, Ostrowski MC, Lozano G. Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein. Genes Dev 31(18):1847-1857, 2017. PMID: 29021240.
- El Beaino M, Araujo DM, Lazar AJ, Lin PP. Synovial sarcoma: Advances in diagnosis and treatment identification of new biologic targets to improve multimodal therapy. Ann Surg Oncol 24(8):2145-2154, 2017. PMID: 28397189.
- Gopalakrishnan V, Amini B, Wagner MJ, Nowell EN, Lazar AJ, Lin PP, Benjamin RS, Araujo DM. Synovial sarcoma of the head and neck: A single institution review. Sarcoma:8 pages, 2017. PMID: 28655993.
- McConnell M, Kumar R, Amini B, Lin PP, Wang WL. Calcified synovial metastasis in the knee from renal cell carcinoma: a case report. Skeletal Radiol 46(1):123-127, 2017. PMID: 27761602.
- Moon BS, Dunbar DJ, Lin PP, Satcher RL, Bird JE, Lewis VO. Is it appropriate to treat sarcoma metastases with intramedullary nailing?. Clin Orthop Relat Res 475(1):212-217, 2017.
- Bird JE, Morse LJ, Feng L, Wang WL, Lin PP, Moon BS, Lazar AJ, Satcher RL, Madewell JE, Lewis VO. Non-Radiographic risk factors differentiating atypical lipomatous tumors from lipomas. Front Oncol 6:197, 2016. PMID: 27713864.
- El Beaino ME, Araujo DM, Gopalakrishnan V, Lazar AJ, Lin PP. Prognosis of T1 synovial sarcoma depends upon surgery by oncologic surgeons. J Surg Oncol 114(4):490-494, 2016. PMID: 27220538.
- Kim Y-I, Kang HG, Kim JH, Kim S-K, Lin PP, Kim HS. Closed intramedullary nailing with percutaneous cement augmentation for long bone metastases. Bone Joint J 98-B(5):703-709, 2016.
- Bishop AJ, Zagars GK, Allen P, Moon BS, Lin PP, Lewis VO, Guadagnolo BA. Treatment-related fractures after combined modality therapy for soft-tissue sarcomas of the proximal lower extremity: Can the risk be mitigated?. Pract Radiat Oncol 6(3):194-200, 2016. PMID: 27126136.
- Etchebehere M, Lin PP, Bird JE, Satcher RL, Moon BS, Yu J, Li L, Lewis VO. Patellar resurfacing: Does it affect outcomes of distal femoral replacement after distal femoral resection?. J Bone Joint Surg Am 98(7):544-551, 2016. PMID: 27053582.
- Etchebehere M, Lin PP, Moon BS, Yu J, Li L, Lewis VO. Patellar height decreasing after distal femur endoprosthesis reconstruction does not affect functional outcome. J Arthroplasty 31(2):442-445, 2016. PMID: 26601638.
- Morse LJ, Lin PP. Groin and medial thigh pain in a 17-year old girl. (DOI: 10.1007/s11999-015-4628-8). Clin Orthop Relat Res 474(2):594-599, 2016. PMID: 26573321.
- Kotwal S, Moon B, Lin P, Satcher R, Lewis V. Total humeral endoprosthetic replacement following excision of malignant bone tumors. Sarcoma:9 pages, 2016. PMID: 27042158.
- Arteau A, Lewis VO, Moon BS, Satcher RL, Bird JE, Lin PP. Tibial growth disturbance following distal femoral resection and expandable endoprosthetic reconstruction. J Bone Joint Surg 97(22):1877, 2015. PMID: 26582624.
- Fan Z, Patel S, Lewis VO, Guadagnolo BA, Lin PP. Should high-grade extraosseous osteosarcoma be treated with multimodality therapy like other soft tissue sarcomas?. Clin Orthop Relat Res 473(11):3604-3611, 2015. PMID: 26197952.
- Tseng WW, Zhou S, To CA, Thall PF, Lazar AJ, Pollock RE, Lin PP, Cormier JN, Lewis VO, Feig BW, Hunt KK, Ballo MT, Patel S, Pisters PW. Phase I adaptive dose-finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high-risk extremity and trunk soft tissue sarcoma. Cancer 121(20):3659-3667, 2015. PMID: 26177983.
- Lin PP, Kang HG, Kim YI, Kim JH, Kim HS. Minimally invasive surgery for femoral neck fractures using bone cement infusible hollow-perforated screw in high-risk patients with advanced cancer. Surg Oncol 24(3):226-231, 2015. PMID: 26051408.
- Bishop AJ, Zagars GK, Moon BS, Lin PP, Lewis VO, Guadagnolo BA. Combined limb-sparing surgery and radiation therapy to treat sarcomas of the hands and feet: Long-term cancer outcomes and morbidity. Int J Radiat Oncol Biol Phys 92(5):1060-1068, 2015. PMID: 26194681.
- Nazarian A, Entezari V, Zurakowski D, Calderon N, Hipp JA, Villa-Camacho JC, Lin PP, Cheung FH, Aboulafia AJ, Turcotte R, Anderson ME, Gebhardt MC, Cheng EY, Terek RM, Yaszemski M, Damron TA, Snyder BD. Treatment planning and fracture prediction in patients with skeletal metastasis with CT-based rigidity analysis. Clin Cancer Res 21(11):2514-2519, 2015.
- Pan HY, Mahajan A, Daw Bitar, N, Ludwig JA, Hess KR, Morani A, Wang WL, Lin PP, Paulino AD. Prognostic factors and patterns of relapse in Ewing sarcoma patients treated with chemotherapy and R0 resection. Intl J Radiat Oncol Biol Phys 92(2):349-357, 2015.
- Sensarma A, Madewell JE, Meis JM, Kumar R, Lin PP, Amini B. Regression of an enchondroma: A case report and proposed etiology. Skeletal Radiol 44(5):739-742, 2015.
- Moon B, Lin P, Satcher R, Bird J, Lewis V. Intramedullary nailing of femoral diaphyseal metastases: Is it necessary to protect the femoral neck?. Clin Orthop Relat Res 473(4):1499-1502, 2015. PMID: 25424158.
- Janku F, Vibat CRT, Kosco K, Holley VR, Cabrilo G, Meric-Bernstam F, Stepanek VM, Lin PP, Leppin L, Hassaine L, Poole JC, Kurzrock R, Erlander MG. BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease. Oncotarget 5(11):3607-3610, 2014. PMID: 25003820.
- Takeuchi A, Lewis VO, Satcher RL, Moon BS, Lin PP. What are the factors that affect survival and relapse after local recurrence of osteosarcoma?. Clin Orthop Relat Res 472(10):3188-3195, 2014. PMID: 24980644.
- Krygier J, Lewis VO, Cannon C, Satcher RL, Moon BS, Lin PP. Operative management of metastatic melanoma in bone may require en bloc resection of disease. Clin Orthop Relat Res 472(10):3196-3203, 2014. PMID: 24989125.
- Kawaguchi A, Sun T, Lin PP, Deavers M, Harun N, Lewis VO. Does ifosfamide therapy improve survival of patients with dedifferentiated chondrosarcoma?. Clin Orthop Relat Res 472(3):983-989, 2014. PMID: 24197392.
- Kawaguchi S, Weiss I, Lin PP, Huh WW, Lewis VO. Radiation therapy is associated with fewer recurrences in mesenchymal chondrosarcoma. Clin Orthop Relat Res 472(3):856-864, 2014. PMID: 23709273.
- Satcher RL, Lin P, Huran N, Feng L, Moon B, Lewis VO. The benefit of surgical management of colorectal carcinoma bone metastases. J Solid Tumors 3(6):27-37, 2013.
- Moon BS, Gilbert NF, Cannon CP, Lin PP, Lewis VO. Distal femur allograft prosthetic composite reconstruction for short proximal femur segments following tumor resection. Adv Orthop:5 pages, 2013. PMID: 24349792.
- Xing Z, Moon BS, Satcher RL, Lin PP, Lewis VO. A long femoral stem is not always required in hip arthroplasty for patients with proximal femur metastases. Clin Orthop Relat Res 471(5):1622-1627, 2013. PMID: 23361930.
- Satcher RL, Lin P, Harun N, Moon B, Feng L, Lewis VO. Surgical management of appendicular skeletal metastases in thyroid carcinoma. Int J Surg Oncol:12 pages. e-Pub 2012.
- Chen LL, Chen X, Choi H, Sang H, Chen LC, Zhang H, Gouw L, Andtbacka RH, Chan BK, Rodesch CK, Jimenez A, Cano P, Jones KA, Oyedeji CO, Martins T, Hill HR, Schumacher J, Willmore C, Scaife CL, Ward JH, Morton K, Randall RL, Lazar AJ, Patel S, Trent JC, Frazier ML, Lin P, Jensen P, Benjamin RS. Exploiting antitumor immunity to overcome relapse and improve remission duration. Cancer Immunol and Immunother 61(7):1113-1124, 2012. PMID: 22198309.
- Lin PP, Alfawareh MD, Takeuchi A, Moon BS, Lewis VO. Sixty percent 10-year survival of patients with chondrosarcoma after local recurrence. Clin Orthop Relat Res 470(3):670-676, 2012. PMID: 21918803.
- Wang WL, Datz D, Araujo DM, Ravi V, Ludwig JA, Trent JC, Patel SR, Lin PP, Guadagnolo A, Lopez-Terrada D, Dei Tos AP, Lewis VO, Lev D, Pollock RE, Zagars GK, Benjamin RS, Madewell JE, Lazar AJ. Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and preoperative radiation therapy. Clin Sarcoma Res 2:25-32, 2012. PMID: 23272660.
- Moon B, Lin P, Satcher R, Lewis V. Simultaneous nailing of skeletal metastases: Is the mortality really that high?. Clin Orthop Relat Res 469(8):2367-2370, 2011. PMID: 21328019.
- Kim JH, Kang HG, Kim JR, Lin PP, Kim HS. Minimally invasive surgery of humeral metastasis using flexible nails and cement in high-risk patients with advanced cancer. Surgical Oncology 20(1):e32-e37, 2011. PMID: 20870403.
- Lin PP, Wang Y, Lozano G. Mesenchymal stem cells and the origin of Ewing's sarcoma. Sarcoma: 8 pages, 2011. PMID: 20953407.
- Merriman DJ, Deavers MT, Czerniak B, Lin PP. Massive desmoplastic fibroblastoma with scapular invasion - A case report. Orthopedics 33(8), 2010. PMID: 20704102.
- Lin PP, Pandey MK, Jin F, Raymond AK, Akiyama H, Lozano G. Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice. Carcinogenesis 30(10):1789-1795, 2009. PMID: 19635748.
- Gupta GR, Yasko AW, Lewis VO, Cannon CP, Raymond AK, Pate S, Lin PP. Risk of local recurrence after deltoid-sparing resection for osteosarcoma of the proximal humerus. Cancer 115:3767-3773, 2009. PMID: 19517468.
- Gilbert NF, Yasko AW, Oates SD, Lewis VO, Cannon CP, Lin PP. Allograft-prosthetic composite reconstruction of the proximal part of the tibia. An analysis of the early results. J Bone Joint Surg Am 91(7):1646-56, 2009. PMID: 19571087.
- Ofek G, Willard VP, Koay EJ, Hu JC, Lin P, Athanasiou KA. Mechanical characterization of differentiated human embryonic stem cells. J Biomech Eng 131(6):061011, 2009. PMID: 19449965.
- Barnea Y, Lin P, Reece G. Modified tibial turn-up fillet flap for repair of extensive composite defects of the thigh. Ann Plast Surg 62:170-172, 2009. PMID: 19158528.
- Lahat G, Dhuka AR, Lahat S, Lazar AJ, Lewis VO, Lin PP, Feig B, Cormier JN, Hunt KK, Pisters PW, Pollock RE, Lev D. Complete soft tissue sarcoma resection is a viable treatment option for select elderly patients. Ann Surg Onc 16:2579-2586, 2009. PMID: 19557478.
- Lin PP, Pandey MK, Jin F, Xiong S, Deavers M, Parant JM, Lozano GM. EWS-FLI-1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model. Cancer Res 68:8968-8975, 2008. PMID: 18974141.
- Cannon CP, Lin PP, Lewis VO, Yasko AY. Management of radiation-associated fractures. J Am Acad Orthop Surg 16:541-549, 2008. PMID: 18768711.
- Lin PP, Brown C, Raymond AK, Deavers MT, Yasko AW. Aneurysmal bone cysts recur at juxtaphyseal locations in skeletally immature patients. Clin Orthop Relat Res 466(3):722-728, 2008. PMID: 18202898.
- Pisters PW, Pollock RE, Lewis VO, Yasko AW, Cormier JN, Respondek PM, Feig BW, Hunt KK, Lin PP, Zagars G, Wei C, Ballo MT. Long-term results of prospective trial of surgery alone with selective use of radiation for patients with T1 extremity and trunk soft tissue sarcomas. Ann Surg 246:675-682, 2007.
- Lin PP, Mirza AN, Lewis VO, Cannon CP, Tu SM, Tannir NM, Yasko AW. Patient survival after surgery for osseous metastases from renal cell carcinoma. J Bone Joint Surg Am 89:1794-1801, 2007.
- Normand, AN, Cannon CP, Lewis VO, Lin PP, Yasko AW. Curettage of biopsy-diagnosed grade 1 periacetabular chondrosarcoma. Clin Orthop Relat Res 459:146-149, 2007.
- Yasko AW, Rutledge J, Lewis VO, Lin PP. Disease-and recurrence-free survival after surgical resection of solitary bone metastases of the pelvis. Clin Orthop Relat Res 459:128-132, 2007.
- Cannon CP, Lin PP, Lewis VO, Yasko AW. Acetabular outcome after hip hemiarthroplasty in patients with tumors. Clin Orthop Relat Res 457:183-187, 2007.
- Costelloe CM, Kumar R, Yasko AW, Murphy WA, Stafford RJ, Lewis VO, Lin PP, Madewell JE. Imaging characteristics of locally recurrent tumors of bone. Am J Roentgenol 188:855-863, 2007.
- Lin PP, Jaffe N, Herzog CE, Costelloe CM, Deavers MT, Kelly JS, Patel SR, Madewell JE, Lewis VO, Cannon CP, Benjamin RS, Yasko AW. Chemotherapy response is an important predictor of local recurrence in Ewing's sarcoma. Cancer 109:603-611, 2007.
- Lin PP, Pino ED, Normand AN, Deavers MT, Cannon CP, Ballo MT, Pisters PW, Pollock RE, Lewis VO, Zagars GK, Yasko AW. Periosteal margin in soft-tissue sarcoma. Cancer 109:598-602, 2007.
- Pan T, Fengshuo L, Hao X, Wang S, Lin PP et al. BIGH3 mediates apoptosis and gap junction failure in osteocytes during renal cell carcinoma bone metastasis progression. Cancer Lett. PMID: 38849015.
- Kim M, Maldonado JA, Pandey P, El Alam MB, Lin PP, et al. Single-fraction radiation retreatment for bone metastases: role of a rapid access clinic. BMJ Support Palliat Care.
- McChesney GR, Al Farii H, Singleterry S, Lewis VO, Moon BS, Satcher RL, Bird JE, Lin PP. Can periprosthetic joint infection of tumor prostheses be controlled with debridement, antibiotics, and implant retention?. Clin Orthop Relat Res. PMID: 38991232.
- Patel RR, Delclos GL, DeSantis SM, Cannell MB, Lupo PJ, Lin PP, Araujo DM. Epidemiological trends of synovial sarcoma by primary tumor sites in the US from 2000 to 2020. Cancer Epidemiology. PMID: 39048411.
Manuals, Teaching Aids, Other Teaching Publications
- Randall L, Aboulafia A, Morris C, Lin P (Section Editor), Benevenia J, Holt G. Orthopaedic Knowledge Update: Musculoskeletal Tumors 3. American Academy of Orthopaedic Surgeons: Rosemont, 2014.
Other Articles
- Singh R, Madewell J, Rao P, Bean G, Czerniak B, Lin P Intraosseous lipoma with subsequent esophageal carcinoma metastasis. Open J Med Imaging 2:64-67, 2012.
- Lin PP, Moussallem CD, Deavers MT Secondary chondrosarcoma. J Am Acad Orthop Surg 18(10):608-615, 2010.
- Gilbert NF, Cannon CP, Lin PP, Lewis VO Soft tissue sarcoma. J Am Acad Orthop Surg 17:40-47, 2009.
- Cannon CP, Mirza AN, Lin PP, Lewis VO, Yasko AW Proximal femoral endoprosthesis for the treatment of metastatic disease. Orthopedics (Online) 31:361, 2008.
- Costelloe CM, Yasko AW, Murphy WA, Kumar R, Lewis VO, Lin PP, Stafford J, Madewell JE MRI of locally recurrent soft tissue tumors of the musculoskeletal system. The Internet Journal of Radiology 5(2), 2007.
Book Chapters
- Dirk SM, Lin P, Buerger S, Cicotte KN, Reece G, Hedberg-Dirk E. Biomimetic approaches to peripheral neuroprosthetic interfaces (Volume 1: Bioinspired Materials). In: Handbook of Biomimetics and Bioinspiration. World Scientific Publishing Co: Singapore, 121-151, 2014.
- Costelloe CM, Ueno NT, Lin PP, Yu TK, Hayashi N, Madewell JE. Bone metastases. In: Oncologic Imaging: A Multidisciplinary Approach. Elsevier: Philadelphia, 591-609, 2012.
- Lin PP. Sarcomas of bone. In: Advanced Therapy in Surgical Oncology. BC Decker, Inc: Canada, 617-635, 2008.
- Lin PP, Healey JH. Sarcomas of bone. In: Surgical Oncology, Contemporary Principles & Practice. McGraw-Hill: New York, 1015-1053, 2001.
Books (edited and written)
- Lin, PP. Bone Sarcoma. In: MD Anderson Cancer Care Series. Ed(s) Lin PP, Patel S. Springer: New York, 2013.
- Wilson FC, Lin PP, editors. General Orthopaedics. MacGraw-Hill, 1997.
Grant & Contract Support
Title: | A genome-wide screen for cooperating mutations in Ewing sarcoma |
Funding Source: | Children Sarcoma Initiative and the Triumph Over Kid Cancer Foundation |
Role: | Principal Investigator |