Peiying Yang, MS, PhD
Department of Palliative, Rehabilitation and Integrative Medicine, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Professor, Department of Palliative, Rehabilitation, and Integrative Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1997 | University of Maine, Orono, Maine, US, Nutritional Biochemistry, Ph.D |
| 1990 | Beijing University of Traditional Chinese Medicine, Beijing, CN, Pharmacology, M.S |
| 1987 | Beijing University of Traditional Chinese Medicine, Beijing, CN, Traditional Chinese Medicine, BS |
Postgraduate Training
| 1998-2004 | Postdoctoral Fellowship, The University of Texas MD Anderson Cancer Center, Houston |
Experience & Service
Faculty Academic Appointments
Associate Professor, Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2023
Assistant Professor, Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2016
Assistant Professor, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - 2013
Assistant Professor, Department of General Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - 2015
Faculty, The University of Texas Graduate School of Biomedical Science, Houston, TX, 2007 - 2015
Assistant Professor, Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006 - 2008
Assistant Professor, Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006 - 2008
Instructor, Department of Experimental Therapeutics, UT MD Anderson Cancer Center, Houston, TX, 2003 - 2006
Other Professional Positions
Consultantships, ReHeva Biosciences Inc, Dublin, OH, USA, 2022 - Present
Consultantships, Anhui JinChan Biochemistry Sharing Inc, Anhui, P.R. China, 2009 - 2014
Senior Project Manager of Pharmaceutical Development Center, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007 - 2008
Consultantships, Phoenix Biotechnology, San Antonio, 2004 - Present
Director of R&D and Formulation, International Nutraceutical Corporation, Ogden, UT, 1997 - 1998
Extramural Institutional Committee Activities
Co-Chair, Faculty Senate Welfare Committee, The University of Texas MD Anderson Cancer Center, 2022 - Present
Member, Mid-Career Faculty Committee, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, Faculty Senate Welfare Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Member, Faculty Senate Research Affair Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2018 - 2021
Ex-Officio Member, Focus on Junior Faculty Steering Committee, The University of Texas MD Anderson Cancer Center, 2017 - Present
Member, Bionutrition Research Core Retreat Committee, The University of Texas MD Anderson Cancer Center, 2015
Member, Faculty Academic Review Committee (FARC), The University of Texas MD Anderson Cancer Center, 2015 - 2018
Member, Review Committee for DoCM Faculty Recognition and Award Program, The University of Texas MD Anderson Cancer Center, 2013
Member, Multidisciplinary Research Advisory Committee, The University of Texas MD Anderson Cancer Center, 2013 - 2016
Member, International Oncology Center for TCM, The University of Texas MD Anderson Cancer Center, 2005 - 2015
Editorial Activities
Associate Editor, Inflammation Pharmacology, 2022 - Present
Editorial Board Member, Holistic Integrative Oncology, 2022 - Present
Editorial Board Member, Longhua Chinese Medicine, 2020 - Present
Honorary Member, Oncology Reports, 2020 - Present
Editorial Board Member, Oncology Report, 2020 - Present
Editorial Board Member, Journal of Current Research: Integrative Medicine, 2017 - Present
Associate Editor, Journal of Integrative Cancer Therapy, 2012 - Present
Editorial Advisory Board, Pharmaceutical Crops, 2010
Honors & Awards
| 2004 | Prostate Cancer Research Program Award |
| 1995 | Gordon E. Ramsdell Scholarship |
| 1995 | Merna Monroe Kappa Omicron Nu Scholarship |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2023. Targeting Myc signaling in cancer with mistletoe lectin. Houston, Texas, US.
- 2022. A role of cardiac glycoside in glioblastoma multiforme. Conference. A role of cardiac glycoside in glioblastoma multiforme. Houston, TX, US.
- 2021. Integrative Medicine and Cancer. Conference. Integrative Medicine and Cancer. Houston, TX, US.
- 2021. The Role of Natural Products in Cancer Care. Conference. The Role of Natural Products in Cancer Care. Houston, TX, US.
- 2020. Sugar and Breast Cancer: What we have learned. Conference. Sugar and Breast Cancer: What we have learned. Houston, TX, US.
- 2019. Sugar and Breast Cancer: What we have learned. Conference. Sugar and Breast Cancer: What we have learned. Houston, TX, US.
- 2019. Sugar and Breast Cancer: What we have learned. Energy Balance Seminar. Conference. Sugar and Breast Cancer: What we have learned. Energy Balance Seminar. Houston, TX, US.
- 2019. AISS: A Note to My Younger Self - Panel Session with Postdocs. Conference. AISS: A Note to My Younger Self - Panel Session with Postdocs. Houston, TX, US.
- 2018. Natural Product Drug Discover: From Bedside to Bench. Conference. Natural Product Drug Discover: From Bedside to Bench. Houston, TX, US.
- 2018. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Conference. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Houston, TX, US.
- 2017. Dietary sugar and cancer. Conference. Dietary sugar and cancer. Houston, TX, US.
- 2017. Diet and cancer. Conference. Diet and cancer. Houston, TX, US.
- 2017. Lifestyle and cancer updates, Prostate Cancer Active Surveillance Support Group Meeting. Conference. Lifestyle and cancer updates, Prostate Cancer Active Surveillance Support Group Meeting. Houston, TX, US.
- 2017. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Conference. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Houston, TX, US.
- 2016. Nutrition and cancer_updates. Conference. Nutrition and cancer_updates. Houston, TX, US.
- 2016. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Conference. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Houston, TX, US.
- 2015. Dietary sucrose induces tumorigenesis in mammary gland partially through 12-lipoxygenase pathway. Conference. Dietary sucrose induces tumorigenesis in mammary gland partially through 12-lipoxygenase pathway. Houston, TX, US.
- 2015. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Conference. Preclinical evaluation of natural products or nutritional supplements as Chemotherapeutic or Chemopreventive Agents. Houston, TX, US.
- 2015. Mistletoe extract inhibits the proliferation of human hepatocellular carcinoma cells by targeting c-Myc signaling and cancer cell metabolism. Conference. Mistletoe extract inhibits the proliferation of human hepatocellular carcinoma cells by targeting c-Myc signaling and cancer cell metabolism. Houston, TX, US.
- 2015. The Benefits and Risks of Nutritional Supplements-Updates. Conference. The Benefits and Risks of Nutritional Supplements-Updates. Houston, TX, US.
- 2014. Bioactive Lipids and Cancer. Conference. Bioactive Lipids and Cancer. Houston, TX, US.
- 2014. Bioactive lipids and cancer. Conference. Bioactive lipids and cancer. Houston, TX, US.
- 2014. Huachansu and Herb Medicine in Cancer Care. Conference. Huachansu and Herb Medicine in Cancer Care. Houston, TX, US.
- 2013. Integrative Oncology and healthy lifestyle. Conference. Integrative Oncology and healthy lifestyle. Houston, TX, US.
- 2012. Chemopreventive effect of omega-3 fatty acids in lung cancer. Conference. Chemopreventive effect of omega-3 fatty acids in lung cancer. Houston, TX, US.
- 2012. Preclinical Research Overview. Conference. Preclinical Research Overview. Houston, TX, US.
- 2012. The benefit and risks of nutritional supplements for cancer management. Conference. The benefit and risks of nutritional supplements for cancer management. Houston, TX, US.
- 2012. Bioactive Lipids, natural products and cancer management. Conference. Bioactive Lipids, natural products and cancer management. Houston, TX, US.
- 2012. Changes in eicosanoid metabolism in malignant disease: An approach to control of cancers. Conference. Changes in eicosanoid metabolism in malignant disease: An approach to control of cancers. Houston, TX, US.
- 2011. Health lifestyle and cancer prevention. Conference. Health lifestyle and cancer prevention. Houston, TX, US.
- 2011. The Benefit and Risks of Nutritional Supplements. Conference. The Benefit and Risks of Nutritional Supplements. Houston, TX, US.
- 2011. Natural Products and Cancer Management. Conference. Natural Products and Cancer Management. Houston, TX, US.
Regional Presentations
- 2021. Research on microgreen. Maestros and Mentors Masterclass: Moonflower Farms Edition. Faculty Vitality & Engagement. Conference. Research on microgreen. Maestros and Mentors Masterclass: Moonflower Farms Edition. Faculty Vitality & Engagement, US.
- 2017. Not So Sweet: The Effect of Sugar in Cancer Progression. Conference. Not So Sweet: The Effect of Sugar in Cancer Progression, US.
- 2011. Sweet gum Extract inhibits the proliferation of prostate cancer through dual inhibition of PI3K/Akt and mtor pathways. Conference. Sweet gum Extract inhibits the proliferation of prostate cancer through dual inhibition of PI3K/Akt and mtor pathways, US.
National Presentations
- 2022. From bedside to the bench: mechanistic study of Chinese Medicine in cancer treatment. Conference. From bedside to the bench: mechanistic study of Chinese Medicine in cancer treatment. (Virtual), US.
- 2022. Therapeutic potential of mistletoe extract in liver cancer. Conference. Therapeutic potential of mistletoe extract in liver cancer. (Virtual), US.
- 2022. Nutrition and cancer: how eating will impact your cancer. Conference. Nutrition and cancer: how eating will impact your cancer. (Virtual), US.
- 2020. Compound Kushen Injection Prevents Radiation-Induced Pneumonitis and its potential mechanism. Conference. Compound Kushen Injection Prevents Radiation-Induced Pneumonitis and its potential mechanism. (Virtual), US.
- 2018. Mistletoe Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma By Targeting c-Myc Signaling. Conference. Mistletoe Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma By Targeting c-Myc Signaling. Cleveland, OH, US.
- 2018. Fraxini and Mistletoe Lectins Inhibit the Proliferation of Hepatocellular Carcinoma by Promoting Proteasomal Degradation of c-Myc,-. Conference. Fraxini and Mistletoe Lectins Inhibit the Proliferation of Hepatocellular Carcinoma by Promoting Proteasomal Degradation of c-Myc,-. Italy, US.
- 2017. Cancer Cell Metabolism Revealed by Direct Sample Analysis with MALDI Mass Spectrometry. Poster Presentation. Conference. Cancer Cell Metabolism Revealed by Direct Sample Analysis with MALDI Mass Spectrometry. Poster Presentation. Waltham, MD, US.
- 2017. Career Development in Integrative Oncology - Panel discussion and Q&A. Conference. Career Development in Integrative Oncology - Panel discussion and Q&A. Chicago, IL, US.
- 2016. Development of natural products for cancer prevention and treatment. Conference. Commemorating conference for Clinical Research Center for Traditional Medicine. Daejeon.
- 2016. Molecular Mechanisms and Clinical evaluation of omega-3 fatty acids in cancer. Conference. Natural Product Workshop. Washington, DC, US.
- 2015. Dietary sugar induces tumorigenesis in mammary gland partially through 12 lipoxygenase pathways. Poster Presentation. Conference. Dietary sugar induces tumorigenesis in mammary gland partially through 12 lipoxygenase pathways. Poster Presentation. Philadelphia, PA, US.
- 2015. Cyclooxygenase-2 knockout inhibits K-Ras induced lung carcinogenesis. Poster Presentation. Conference. Cyclooxygenase-2 knockout inhibits K-Ras induced lung carcinogenesis. Poster Presentation. Philadelphia, PA, US.
- 2015. Integrative Medicine: An Evidence-Based Approach. Conference. LACE. Houston, TX, US.
- 2015. Mistletoe Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cells by Induction of Apoptosis and Down Regulation of c-MYC. Poster Presentation. Conference. AACR Special Conference on Myc Oncogene. San Diego, US.
- 2014. Na,K-ATPase in GI cancer. Conference. Na,K-ATPase in GI cancer. Baltimore, MD, US.
- 2014. Direct Identification of Omega-3/6 Fatty Acid Incorporated Phosphatidylcholine in Mouse Serum and Tissue by MALDI-MS and LC-MS Based Metabolic Profiling. Poster Presentation. Conference. Direct Identification of Omega-3/6 Fatty Acid Incorporated Phosphatidylcholine in Mouse Serum and Tissue by MALDI-MS and LC-MS Based Metabolic Profiling. Poster Presentation. Baltimore, MD, US.
- 2014. Mistletoe extract inhibits the proliferation of human hepatocellular carcinoma cells by induction of apoptosis. Poster Presentation. Conference. Mistletoe extract inhibits the proliferation of human hepatocellular carcinoma cells by induction of apoptosis. Poster Presentation. San Diego, CA, US.
- 2014. Zyflamend, a multi-herbal product, inhibits the growth of triple negative breast cancer cells. Poster Presentation. Conference. Zyflamend, a multi-herbal product, inhibits the growth of triple negative breast cancer cells. Poster Presentation. San Diego, CA, US.
- 2013. Chemopreventive effect of omega-3 fatty acid, EPA, in non-small cell lung cancer through formation of PGE3 and inhibition of PI3Kinase/mTOR pathways. Poster Presentation. Conference. Chemopreventive effect of omega-3 fatty acid, EPA, in non-small cell lung cancer through formation of PGE3 and inhibition of PI3Kinase/mTOR pathways. Poster Presentation. Washington DC, MD, US.
- 2013. Respiratory Motion Management for High-Precision Small Animal Irradiation. Poster Presentation. Conference. Respiratory Motion Management for High-Precision Small Animal Irradiation. Poster Presentation. Washington DC, MD, US.
- 2013. PBO-05204, a supercritical CO2 extract of Nerium Oleander, inhibits the growth of human pancreatic cancer in a Panc-1 orthotopic model by down regulation of PI3K/mTOR pathways. Poster Presentation. Conference. PBO-05204, a supercritical CO2 extract of Nerium Oleander, inhibits the growth of human pancreatic cancer in a Panc-1 orthotopic model by down regulation of PI3K/mTOR pathways. Poster Presentation. Washington DC, MD, US.
- 2013. Celecoxib inhibits the growth of IBC tumors by suppressing the regulation of cancer stem-like cells by Nodal. Poster Presentation. Conference. Celecoxib inhibits the growth of IBC tumors by suppressing the regulation of cancer stem-like cells by Nodal. Poster Presentation. San Antonio, TX, US.
- 2012. Huachansu inhibits proliferation of Non-Hodgkins lymphoma cells by induction of apoptosis. Conference. Huachansu inhibits proliferation of Non-Hodgkins lymphoma cells by induction of apoptosis, US.
- 2012. MALDI mass spectrometric imaging reveals differential lipid metabolism in cancer. Poster Presentation. Conference. MALDI mass spectrometric imaging reveals differential lipid metabolism in cancer. Poster Presentation, US.
- 2012. inflammatory pathways as an effective therapeutic approach to suppress tumorigenicity and prevent metastasis in inflammatory breast cancer. Poster Presentation. Conference. inflammatory pathways as an effective therapeutic approach to suppress tumorigenicity and prevent metastasis in inflammatory breast cancer. Poster Presentation. Chicago, IL, US.
- 2012. EPA derived PGE3 inhibits proliferation and angiogenesis of non-small cell lung cancer A549 cells though the EGFR and MAKinase pathways. Poster Presentation. Conference. EPA derived PGE3 inhibits proliferation and angiogenesis of non-small cell lung cancer A549 cells though the EGFR and MAKinase pathways. Poster Presentation. Chicago, IL, US.
- 2012. Huachansu inhibits proliferation of non-Hodgkin lymphoma cells by inducation of apoptosis. Poster Presentation. Conference. Huachansu inhibits proliferation of non-Hodgkin lymphoma cells by inducation of apoptosis. Poster Presentation. Chicago, IL, US.
- 2011. Development of Chansu Products for Cancer Treatment. Conference. NCI, US.
- 2010. Sweet gum extract inhibits proliferation of prostate cancer PC3 cells through suppression of mTOR pathway, but through MAPK pathways in DU145 cells. Poster Presentation. Conference. Sweet gum extract inhibits proliferation of prostate cancer PC3 cells through suppression of mTOR pathway, but through MAPK pathways in DU145 cells. Poster Presentation, US.
- 2009. The effect of homeopathic remedies on proliferation of breast cancer cells. Conference. The effect of homeopathic remedies on proliferation of breast cancer cells, US.
- 2009. The anti-angiogenic activity of sweet leaf tea extract is mediated by the down-regulation of bFGF and VEGF receptor. Poster Presentation. Conference. The anti-angiogenic activity of sweet leaf tea extract is mediated by the down-regulation of bFGF and VEGF receptor. Poster Presentation. Denver, CO, US.
- 2008. Oleandrin –mediated inhibition of human tumor cell proliferation: importance of Na,K-ATPase alpha subunits as drug target. Poster Presentation. Conference. Oleandrin –mediated inhibition of human tumor cell proliferation: importance of Na,K-ATPase alpha subunits as drug target. Poster Presentation. San Diego, CA, US.
- 2008. Huachanusu inhibits growth of human pancreatic cancer Panc-1 and BxPC3 xenograft tumors. Poster Presentation. Conference. Huachanusu inhibits growth of human pancreatic cancer Panc-1 and BxPC3 xenograft tumors. Poster Presentation. San Diego, CA, US.
- 2008. Sweet gum extract inhibits proliferation of prostate cancer through dual inhibition of PI3K/Akt and mTOR pathways. Poster Presentation. Conference. Sweet gum extract inhibits proliferation of prostate cancer through dual inhibition of PI3K/Akt and mTOR pathways. Poster Presentation. San Diego, CA, US.
- 2006. The involvement of Na,K-ATPase in Huachansu mediated pancreatic cancer cell death. Conference. Traditional Chinese Medicine and Cancer Research: Fostering Collaborations; Advancing the Science, US.
- 2006. Anti-proliferative activity of Huachansu, a toad skin extract, against human malignant melanoma cells. Poster Presentation. Conference. 97th AACR Annual Meeting. Washington, DC, US.
- 2006. Conjugated linoleic acid inhibits COX2 transcription in mouse skin through the peroxisome proliferators-activated receptor α. Poster Presentation. Conference. 97th AACR Annual Meeting. Washington DC, US.
- 2006. Antitumor activity of fish oils in human lung cancer is associated with altered formation of PGE2 and PGE3. Poster Presentation. Conference. 97th AACR Annual Meeting. Washington DC, US.
- 2006. Modulation of 7,12-dimethylbenz[a] anthrancene (DMBA) induced oral carcinogenesis in hamster cheek pouch by the 5-lipoxygenase/leukotriene A4 hydrolase/leukotriene B4 pathway of Arachidonic acid metabolism. Poster Presentation. Conference. 97th AACR Annual Meeting. Washington DC, US.
- 2006. 15-lipoxygenase-1 induction of terminal differentiation and apoptosis in human colonic epithelial cells. Poster Presentation. Conference. 97th AACR Annual Meeting. Washington, DC, US.
- 2005. LC/MS/MS based determination of tissue inflammation profiles: simultaneous determination of COX and LOX derived bioactive lipids. Poster Presentation. Conference. LC/MS/MS based determination of tissue inflammation profiles: simultaneous determination of COX and LOX derived bioactive lipids. Poster Presentation. San Francisco, CA, US.
- 2004. A LC/MS/MS method to analyze tissue eicosanoids: application to EPA-mediated alterations of prostaglandin metabolism. Poster Presentation. Conference. A LC/MS/MS method to analyze tissue eicosanoids: application to EPA-mediated alterations of prostaglandin metabolism. Poster Presentation. Orlando, FL, US.
- 2003. Inhibition of human lung tumor cell proliferation by prostaglandin E3: a COX-2 product derived from fish oil EPA. Oral Presentation. Conference. Inhibition of human lung tumor cell proliferation by prostaglandin E3: a COX-2 product derived from fish oil EPA. Oral Presentation. Washington, DC, US.
- 2002. Relative formation of PGE2 and PGE3 by eicosapentaenoic acid (EPA ) and docosahexaenoic acid (DHA) in human lung cancer cells. Poster Presentation. Conference. Relative formation of PGE2 and PGE3 by eicosapentaenoic acid (EPA ) and docosahexaenoic acid (DHA) in human lung cancer cells. Poster Presentation. San Diego, CA, US.
- 2001. Use of LC/MS/MS to determine celecoxib-mediated alterations of eicosanoid metabolism in human lung cancer. Poster Presentation. Conference. Use of LC/MS/MS to determine celecoxib-mediated alterations of eicosanoid metabolism in human lung cancer. Poster Presentation, US.
International Presentations
- 2023. Update on natural compounds for cancer prevention and symptom management. Invited. San Diego, US.
- 2023. Protective effect of Compound Kushen Injection in Radiation Induced Mucositis. Invited. Nara, JP.
- 2022. PBI-05204, a supercritical CO2 extract of Nerium oleander, suppresses the stemness of glioblastoma stem cells by inhibiting GRP-78 and CD44, Oral Presentation. Conference. PBI-05204, a supercritical CO2 extract of Nerium oleander, suppresses the stemness of glioblastoma stem cells by inhibiting GRP-78 and CD44, Oral Presentation. Scottdale, US.
- 2021. Fraction B from catfish epidermal secretions kills pancreatic cancer cells, inhibits CD 44 expression and stemness, and alters cancer cell metabolism. Oral presentation. Conference. Fraction B from catfish epidermal secretions kills pancreatic cancer cells, inhibits CD 44 expression and stemness, and alters cancer cell metabolism. Oral presentation. Baltimore, US.
- 2019. Not so sweet: the impact of added sugar in breast cancer development and progression. Conference. Not so sweet: the impact of added sugar in breast cancer development and progression. Beijing, CN.
- 2019. Compound Kushen Injection prevents radiation-induced pneumonitis. Conference. Compound Kushen Injection prevents radiation-induced pneumonitis. New York, US.
- 2019. Quxie capsule inhibits the colon tumor growth partially through Foxo1 mediated apoptosis and immune modulation. Conference. Quxie capsule inhibits the colon tumor growth partially through Foxo1 mediated apoptosis and immune modulation. New York, US.
- 2019. Targeting Myc pathway with herbal medicine in liver cancer and melanoma. Conference. Targeting Myc pathway with herbal medicine in liver cancer and melanoma. Tokyo, JP.
- 2019. The development of Traditional Chinese Medicine for cancer care through international collaboration. Conference. The development of Traditional Chinese Medicine for cancer care through international collaboration. Hangzhou, CN.
- 2019. The development of traditional Chinese medicine and targeted therapy in cancer care. Conference. The development of traditional Chinese medicine and targeted therapy in cancer care. Beijing, CN.
- 2018. Exploring the preclinical evaluation method of TCM in Cancer. Conference. Exploring the preclinical evaluation method of TCM in Cancer. Beijing, CN.
- 2018. Development of herbal medicine as a targeted anticancer therapy-preclinical and translational experience. Conference. Development of herbal medicine as a targeted anticancer therapy-preclinical and translational experience. Shanghai, CN.
- 2018. The preclinical research approach on managing colorectal cancer with Traditional Chinese Medicine. Conference. The preclinical research approach on managing colorectal cancer with Traditional Chinese Medicine. Beijing, CN.
- 2018. Dietary Sugar Induces Tumorigenesis in Mammary Gland Partially through 12-Lipoxygenase and Immune Modulations. Oral presentation. Conference. Dietary Sugar Induces Tumorigenesis in Mammary Gland Partially through 12-Lipoxygenase and Immune Modulations. Oral presentation. Baltimore, US.
- 2017. Natural Products and Nutritional Supplements in Cancer Management – Updates. Conference. Natural Products and Nutritional Supplements in Cancer Management – Updates. Chicago, US.
- 2017. Mistletoe Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cells By Targeting c-Myc Signaling and Metabolism. Conference. Mistletoe Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cells By Targeting c-Myc Signaling and Metabolism. Taiyuan, CN.
- 2017. Dietary Sugar Induces Tumorigenesis in Mammary Gland Partially through 12-Lipoxygenase and Immune Modulations. Oral Presentation. Conference. Dietary Sugar Induces Tumorigenesis in Mammary Gland Partially through 12-Lipoxygenase and Immune Modulations. Oral Presentation. Zurich, CH.
- 2016. Development of mistletoe extract for hepatocellular carcinoma treatment- from bedside to bench. Conference. 2015 International Symposium of Integrative Oncology.
- 2016. The effect of dietary sugar on the chemotherapeutic potential in breast cancer. Oral Presentation. Conference. The effect of dietary sugar on the chemotherapeutic potential in breast cancer. Oral Presentation. Miami, US.
- 2016. Dietary sugar promotes tumorigenesis in mammary gland partially through 12- lipoxygenase pathway. Conference. Dietary sugar promotes tumorigenesis in mammary gland partially through 12- lipoxygenase pathway. Athens, GR.
- 2016. Anti-proliferative Activities of lipid fraction of extract from the Skin of the Catfish Arius Bilineatus, Valenciennes. Poster Presentation. Conference. Anti-proliferative Activities of lipid fraction of extract from the Skin of the Catfish Arius Bilineatus, Valenciennes. Poster Presentation. Chamonix, FR.
- 2016. Mistletoe and hepatocellular carcinoma. Conference. Mistletoe and hepatocellular carcinoma. Rosenfeld, DE.
- 2015. Fraxini inhibits human hepatocellular carcinoma cells growth and liver tumor development through targeting c-Myc signaling and downstream metabolisms. Oral Presentation. Conference. Fraxini inhibits human hepatocellular carcinoma cells growth and liver tumor development through targeting c-Myc signaling and downstream metabolisms. Oral Presentation. Boston, US.
- 2015. Dietary sugar induces tumorigenesis in mammary gland partially through 12 lipoxygenase pathways. Oral Presentation (Best of SIO). Conference. Dietary sugar induces tumorigenesis in mammary gland partially through 12 lipoxygenase pathways. Oral Presentation (Best of SIO). Boston, US.
- 2015. Traditional Chinese Medicine for cancer - can preclinical research of TCM improve the translational potential of TCM?. Conference. Traditional Chinese Medicine for cancer - can preclinical research of TCM improve the translational potential of TCM?. Dalian, CN.
- 2015. The antitumor efficacy of Botanical Drug PBI-05204 in pancreatic cancer – preclinical and clinical development. Oral Presentation. Conference. The antitumor efficacy of Botanical Drug PBI-05204 in pancreatic cancer – preclinical and clinical development. Oral Presentation. Shanghai, CN.
- 2015. Prostaglandin E3 Metabolism and Cancer. Conference. Prostaglandin E3 Metabolism and Cancer. Beijing, CN.
- 2015. Dietary sugar induces tumorigenesis in mammary gland partially through 12 lipoxygenase pathways. Oral Presentation. Conference. 14th Bioactive Lipids, Inflammation and Cancer International Conference. Budapest, HU.
- 2014. Na+/K+-ATPase α1 Subunit, A Novel Target for Hepatocellular Carcinoma. Poster Presentation. Conference. Na+/K+-ATPase α1 Subunit, A Novel Target for Hepatocellular Carcinoma. Poster Presentation. Houston, US.
- 2014. Mistletoe Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cells By Induction of Apoptosis And Down Regulation of C-MYC. Oral Presentation. Conference. Mistletoe Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cells By Induction of Apoptosis And Down Regulation of C-MYC. Oral Presentation. Houston, US.
- 2014. Investigations into the use of quantitative image features to predict tumor phenotype and treatment outcome in lung tumors. Poster Presentation. Conference. Investigations into the use of quantitative image features to predict tumor phenotype and treatment outcome in lung tumors. Poster Presentation. Vancouver, CA.
- 2013. Development of Chansu Products for Cancer Treatment - The Journey Continues. Conference. Development of Chansu Products for Cancer Treatment - The Journey Continues, CN.
- 2013. PBI-05204, A Supercritical CO2 Extract of Nerium Oleander, inhibits the growth of human pancreatic cancer in PANC-1 Orthotopic Model by down-regulation of PI3K/MTOR Pathway. Oral Presentation. Conference. PBI-05204, A Supercritical CO2 Extract of Nerium Oleander, inhibits the growth of human pancreatic cancer in PANC-1 Orthotopic Model by down-regulation of PI3K/MTOR Pathway. Oral Presentation. Vancouver, CA.
- 2012. Comparative Analysis of the Bufonis Venenum by Extraction Methods using Tlc, Hplc, And Lc-ms. Poster Presentation. Conference. Society of Integrative Oncology 9th International Conference. Albuquerque, US.
- 2012. Essential fatty acids in the prevention of non-small cell lung cancer. Conference. Society for Integrative Oncology. Albuquerque, US.
- 2012. EPA derived PGE3 inhibits proliferation and angiogenesis of non-small cell lung cancer A549 cells through inhibition of mTOR pathway. Poster Presentation. Conference. EPA derived PGE3 inhibits proliferation and angiogenesis of non-small cell lung cancer A549 cells through inhibition of mTOR pathway. Poster Presentation. Paris, FR.
- 2011. Cellular location and expression of Na, K-ATPase alpha3 subunits affect the anti-proliferative activity of oleandrin. Oral Presentation. Conference. Cellular location and expression of Na, K-ATPase alpha3 subunits affect the anti-proliferative activity of oleandrin. Oral Presentation. Cleveland, US.
- 2011. Prostate 5LX inhibits proliferation of prostate cancer cells through alteration of the inflammation pathways. Oral Presentation. Conference. Society of Integrative Oncology 8th International Conference. Cleveland, US.
- 2011. Preclinical evaluation of natural products or nutritional supplements as chemotherapeutic or chemopreventive agents. Conference. Preclinical evaluation of natural products or nutritional supplements as chemotherapeutic or chemopreventive agents. Beijing, CN.
- 2010. Sweet gum extract inhibits the proliferation of prostate cancer through dual inhibition of PI3K/AKT and mTOR pathways. Oral Presentation (Best of the SIO). Conference. Society of Integrative Oncology 7th International Conference. New York, US.
- 2009. The effect of homeopathic remedies on proliferation of breast cancer cells. Oral Presentation. Conference. The effect of homeopathic remedies on proliferation of breast cancer cells. Oral Presentation. New York, US.
- 2008. Targeted Botanical Drugs for Cancer Treatment, from Natural Herbs to the Bedside. Conference. Targeted Botanical Drugs for Cancer Treatment, from Natural Herbs to the Bedside, US.
- 2007. Huachansu inhibits growth of human pancreatic cancer Panc-1 and BxPC3 xenograft tumors. Oral Presentation (Best of SIO). Conference. SIO 4th International Conference. San Francisco, US.
- 2007. Antitumor Activity of Fish Oils against Human Lung Cancer Is Associated with Altered Formation of PGE2 And PGE3 And Regulation of AKT Phosphorylation. Oral Presentation. Conference. 10th Bioactive Lipids, Inflammation and Cancer. Montreal, CA.
- 2006. Phase I study of Huachansu in hepatocellular carcinoma, non-small cell lung cancer, and pancreatic cancer. Oral Presentation. Conference. SIO 3rd International Conference. Boston, US.
- 2006. Antitumor activity of fish oils against lung cancer is associated with altered formation of PGE2 and PGE3 and regulation of AKT phosphorylation. Oral Presentation (Best of SIO). Conference. Antitumor activity of fish oils against lung cancer is associated with altered formation of PGE2 and PGE3 and regulation of AKT phosphorylation. Oral Presentation (Best of SIO). Boston, US.
Formal Peers
- 2022. Natural Products for the Development of Novel Anticancer Therapies. Invited.
- 2022. The Impact of Dietary Sugar on Breast Cancer. Invited, AU.
- 2022. Traditional Medicine in Cancer Care Preclinical Perspective. Invited, IL.
- 2019. Natural Products for the Development of Novel Anticancer Therapies. Invited, US.
- 2018. Botanical Drugs in Cancer Treatment. Invited, RO.
- 2017. Not So Sweet: The Effect of Sugar in Cancer Development and Progression. Invited, US.
- 2013. Fish oil derived omega-3 fatty acids and lung cancer prevention. Invited, US.
- 2011. Fish oil/natural products and non-Hodgkin lymphoma. Invited, US.
- 2011. Nutritional Supplements and Cancer: Risk and Benefits. Invited, US.
- 2011. Role of Natural Products in Cancer Prevention and Treatment. Invited, US.
- 2010. Development of targeted natural product in cancer prevention and treatment. Invited. Beijing, CN.
- 2010. Anti-inflammatory activity of wholemega and lifeshield immunity-restoring the balance of lipid mediators. Invited, CR.
- 2009. Fish Oil Supplements As Targeted Preventive or. Invited, NY, US.
Grant & Contract Support
| Date: | 2023 - 2026 |
| Title: | Biologically Active Fractions and Components of Lipids and Proteins, their Anti-diabetic, Anti-Inflammatory, Anti-Cancer, Neurological and Wound Healing Activities in Preparations from the Skin of a Catfish (Arius Bilineatus, Val.) |
| Funding Source: | Kuwait Foundation for the Advancement of Science |
| Role: | Co-PI |
| Date: | 2023 - 2026 |
| Title: | Added sugar as a dietary risk factor for the breast cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP230342 |
| Date: | 2023 - 2028 |
| Title: | Combination therapy to treat cancer related fatigue |
| Funding Source: | Rising Tide Foundation |
| Role: | Collaborator |
| Date: | 2022 - 2027 |
| Title: | Biobehavioral Effects and Mechanisms of Tele-Health Delivery of Lifestyle Interventions for Overweight Women with Breast Cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2022 - 2027 |
| Title: | Electronic cigarette uptake and health impact among cancer patients and survivors motivated to reduce combustible cigarette smoking |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | 1R01CA277768-01 |
| Date: | 2022 - 2026 |
| Title: | Pre-IND Development of polymeric micelles with dual drug payloads for HCC therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | R01CA257842-01A1 |
| Date: | 2021 - 2025 |
| Title: | Prevention of radiation induced lung injury with a botanical product: Inflammatory and immunological mechanisms |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2021 - 2024 |
| Title: | Targeting 12-LOX in sugar induced breast cancer progression |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | R01 CA273255-01 |
| Date: | 2021 - 2026 |
| Title: | Development of Polymeric Micelles with Dual Drug Payloads for HCC Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2021 - 2022 |
| Title: | Evidence-based Natural Product to Improve Treatment Outcomes in Triple Negative Breast Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2020 - 2024 |
| Title: | Biofield Therapy in Oncology: Modulation of Tumor Biology in Pancreatic and Liver Cancer |
| Funding Source: | Emerald Gate Charitable Trust |
| Role: | Co-PI |
| ID: | LS2020-00058378 |
| Date: | 2020 - 2025 |
| Title: | The potential risks and benefits of electronic cigarettes to older smokers at high risk for lung cancer |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | R01CA238478-A1 |
| Date: | 2020 - 2022 |
| Title: | Influence of Medicinal Mushrooms on Human Xenobiotic Metabolizing Enzymes and Transporters |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | R21 |
| Date: | 2020 - 2023 |
| Title: | The potential risks and benefits to adult smokers of switching to a fourth generation electronic cigarette |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | R01DA050966 |
| Date: | 2020 - 2025 |
| Title: | Comprehensive Lifestyle Intervention versus Conventional Health Coaching for Overweight Women with Breast Cancer: Mechanisms and Biobehavioral Outcomes |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2019 - 2024 |
| Title: | Therapeutic potential and immune mechanisms involved with Euphorbia tirucalli in cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2019 - 2022 |
| Title: | Chemoprevention of hepatocellular carcinoma by deactivation of hepatic stellate cells |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-PI |
| Date: | 2019 - 2024 |
| Title: | An EPA-based targeted therapy for triple-negative breast cancer |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Date: | 2019 - 2024 |
| Title: | Development of Chinese herbal medicine for cancer care, |
| Funding Source: | Zhendong Pharmaceutical Inc |
| Role: | PI |
| ID: | LS2019-00007868-GS |
| Date: | 2019 - 2021 |
| Title: | Chemoprevention of Hepatocellular Carcinoma by Disrupting Crosstalk Between c-Myc-expressing Hepatocytes and Hepatic Stellate Cells |
| Funding Source: | Duncan Family Institute for Cancer Prevention and Risk Assessment Seed-funding Research Program |
| Role: | Co-PI |
| Date: | 2019 - 2022 |
| Title: | Antitumor effect of mistletoe in hepatocellular carcinoma via downregulation of Myc signaling and metabolism |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP19036 |
| Date: | 2018 - 2023 |
| Title: | Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family Caregivers, |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | 1R37CA231522-01 |
| Date: | 2018 - 2025 |
| Title: | The effect of the CA102N in the growth of syngeneic mouse colon cancer CT26 model via inflammation and immune modulation |
| Funding Source: | Holy Stone Health Care Inc |
| Role: | PI |
| ID: | LS2018-00055832-GS |
| Date: | 2018 - 2021 |
| Title: | Determination of Therapeutic Effect of Kushen Injection in Lung Tumor and Radiation Inducted Pneumonitis |
| Funding Source: | Zhendong Pharmaceutical Co |
| Role: | PI |
| ID: | LS2017-00054546-GS |
| Date: | 2017 - 2022 |
| Title: | 12-LOX molecular targeting to prevent dietary sucrose induced breast cancer progression |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2017 - 2021 |
| Title: | The Therapeutic Effect of Mistletoe in Hepatocellular Carcinoma by targeting c-Myc |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2017 - 2018 |
| Title: | Reduced sugar feeding study in woman with early stage breast cancer. (This grant is in response to a special RFA on dietary sugar and health) |
| Funding Source: | Laura and John Arnold Foundation |
| Role: | Co-PI |
| Date: | 2017 - 2020 |
| Title: | Evaluation of the Anti-Proliferative and Chemopreventive activity of Pomi-T and its active compounds in Breast and Prostate cancer. (Grant request and scientific protocol approved. Waiting for legal to finalize the SRA) |
| Funding Source: | Helsinn Integrative Care |
| Role: | PI |
| Date: | 2016 - 2018 |
| Title: | Safety Analysis of Anvirzel (hot water extract of Nerium Oleander in mice) |
| Funding Source: | Nerium Biotechnology |
| Role: | PI |
| Date: | 2016 - 2017 |
| Title: | Determination of Biophoton on Modulation of Tumor Biology in Lung Cancer |
| Funding Source: | Bosarge Family Foundation |
| Role: | PI |
| Date: | 2016 - 2021 |
| Title: | 15-LOX-1 Regulation of Resolving Generation to Modulate Colon Cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | R01CA195686 |
| Date: | 2016 - 2018 |
| Title: | The role of protein kinases in NSAIDs elicited breast cancer chemoprevention |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2016 - 2021 |
| Title: | Examining the Effects of Sugar in Promoting the Development of Breast Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2016 - 2021 |
| Title: | 15-LOX-1 modulation of colon cancer promotion by Linoleic acid |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2016 |
| Title: | Alteration of glycerophospholipid metabolism, one of the mechanisms of targeting Na-K-ATPase apha1 subunit in hepatocellular carcinoma treatment |
| Funding Source: | American Association for Cancer Research (AACR) |
| Role: | Mentor |
| Date: | 2015 - 2020 |
| Title: | Metabolomic Impact of Ginger Components on Ulcerative Colitis |
| Funding Source: | NIH/NCCAM |
| Role: | Collaborator |
| Date: | 2015 - 2016 |
| Title: | Determination of the Effect of EMF in Human Breast Cancer Cells and Breast Cancer Orthotopic Models |
| Funding Source: | Applied Photon Medical Technologies |
| Role: | PI |
| Date: | 2015 - 2018 |
| Title: | The Therapeutic Effect of Mistletoe in Hepatocellular Carcinoma by Targeting cMyc |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| Date: | 2015 - 2019 |
| Title: | Composition of steroids and other lipid fractions and proteins, their anti-inflammatory, anti-cancer activities in preparations from the skin of the Arabian Gulf catfish (Arius bilineatus, Valenciennes) |
| Funding Source: | Kuwait National Science Foundation |
| Role: | Co-PI |
| Date: | 2015 - 2018 |
| Title: | Mechanisms of DHA and EPA differential effects on colon cancer chemoprevention |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | RP150195 |
| Date: | 2014 - 2015 |
| Title: | Personalized Integrative Oncology: Targeted Approaches for Optimal Outcomes |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2014 - 2017 |
| Title: | PPAR-delta Regulation of Wnt/B-catenin to Drive Colon Cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| Date: | 2014 - 2017 |
| Title: | Cardiac glycosides and pancreatic cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| Date: | 2014 - 2016 |
| Title: | 15-LOX-1 Requirement for Colon Cancer Chemoprevention by EPA |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Date: | 2014 - 2016 |
| Title: | Targeting the adrenergic receptors for breast cancer prevention |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2014 - 2016 |
| Title: | Regulation of Breast Cancer by Refined Sugar |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2014 - 2016 |
| Title: | Cardiac Glycosides and Pancreatic Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2014 - 2016 |
| Title: | Mistletoe and Hepatocellular Carcinoma |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2014 - 2016 |
| Title: | (PQC5) Early Detection Pancreatic Cancer by Hyperpolarized Silicon Nanoparticles |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | 1R21CA185536-01 |
| Date: | 2013 - 2014 |
| Title: | Novel Molecular Imaging Agents for Her2 positive Breast Cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | HHSN261201300065C |
| Date: | 2013 - 2015 |
| Title: | Oral Paclitaxel Solubilized and Bioenhanced by Food Compounds for Cancer Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5R21CA164408-02 |
| Date: | 2013 - 2015 |
| Title: | Zyflamend and breast cancer prevention |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2013 - 2015 |
| Title: | Research Answers to NCIs Provocative Questions - Group C |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2013 - 2018 |
| Title: | The Role of Bioactive Lipids in Inflammation and Cancer |
| Funding Source: | NIH/NCI |
| Role: | Core Leader |
| ID: | 7 P01 CA077839-13 |
| Date: | 2013 - 2014 |
| Title: | A Natural Micellar Formulation to Reduce Side Effects of Etoposide Chemotherapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1-R21-AT006582-01 |
| Date: | 2012 - 2015 |
| Title: | Chemopreventive Effect of Modified Citrus Pectin in Colon Cancer Animal Model |
| Funding Source: | EcoNugenics |
| Role: | PI |
| Date: | 2012 - 2017 |
| Title: | Meditation for the Treatment of Cognitive Dysfunction after Chemotherapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2012 - 2017 |
| Title: | The role of inflammation on inflammatory breast cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2012 - 2014 |
| Title: | The MDACC Community Clinical Oncology Research Base Program |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5 U10 CA45809-25 |
| Date: | 2012 - 2020 |
| Title: | Community-Based, Phase III Trial of Acupuncture to Treat Chronic Xerostomia |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5R01CA160880-02 |
| Date: | 2012 - 2013 |
| Title: | Prostaglandins and inflammation in colon cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-PI |
| ID: | RP100960 |
| Date: | 2011 - 2018 |
| Title: | The Effect of Sugar in Breast Tumorigenesis and Metastases |
| Funding Source: | Leighton and Linda Steward Foundation |
| Role: | PI |
| Date: | 2011 - 2012 |
| Title: | The role of tryptophan metabolism in the chronic fatigue experienced by chronic myelogenous leukemia (CML) survivors |
| Funding Source: | MDACC Institutional Research Grant (IRG) |
| Role: | Co-PI |
| Date: | 2011 - 2013 |
| Title: | Natural nano-platform for delivering soluble and stable chemopreventive curcumin |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1 R21 AT006582-01 |
| Date: | 2011 - 2016 |
| Title: | Placebo Controlled trial of acupuncture to prevent radiation-induced xerostomia |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5R01CA148707 03 |
| Date: | 2010 - 2013 |
| Title: | Role of Nerium Oleander Extract and Oleandrin on Glioblastoma |
| Funding Source: | Accelerate Brain Cancer Cure Foundation |
| Role: | PI |
| Date: | 2010 - 2014 |
| Title: | Chemopreventive effect of fish oil derived EPA in lung cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 4 R01 CA144053-04 |
| Date: | 2010 - 2015 |
| Title: | A Phase I Study of Sublingual Anvirzel (Nerium oleander) in Advanced Non-Small Cell Lung Cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5 U10 CA045809-24 |
| Date: | 2009 - 2013 |
| Title: | Fish oil (N-3 fatty acids) and Non-Hodgkin's Lymphoma |
| Funding Source: | Gabrielle Angel Foundation |
| Role: | PI |
| ID: | 02-03-02133 |
| Date: | 2009 - 2014 |
| Title: | 15-LOX-1 Effects on Colitis and Colon Cancer |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | 5R01CA106577-05 |
| Date: | 2009 - 2012 |
| Title: | Anti-inflammatory and anticancer activity of Prostate-5Lx and |
| Funding Source: | New Chapter |
| Role: | PI |
| ID: | LS2009-00027076JW |
| Date: | 2008 - 2021 |
| Title: | Antitumor efficacy and relevant mechanism of natural product based on Bufo Bufo toad |
| Funding Source: | Anhui Jinchan Biochemistry Sharers Corp |
| Role: | PI |
| ID: | LS2007-0021289EB |
| Date: | 2008 - 2010 |
| Title: | Antiangiogenic properties of sweet leaf tea extract |
| Funding Source: | NIH/NCCAM |
| Role: | Co-PI |
| ID: | 1R21AT002882-01A2 |
| Date: | 2008 - 2010 |
| Title: | Sweet Leaf Tea and Antiangiogenesis |
| Funding Source: | NIH/NCCAM |
| Role: | Principal Investigator-MDACC |
| ID: | 1R21AT002882 |
| Date: | 2008 - 2011 |
| Title: | Sweet Gum Extract and Late Stage Prostate Cancer |
| Funding Source: | NIH/NCCAM |
| Role: | PI |
| ID: | 1R21AT004514-01A1 |
| Date: | 2008 - 2010 |
| Title: | Sweet Gum Extract and Late Stage Prostate Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 5R21AT4514-2 |
| Date: | 2005 - 2011 |
| Title: | International Center of TCM for Cancer |
| Funding Source: | NCI-DHHS-NIH |
| Role: | Co-I |
| ID: | 1 U19 CA121503 02 |
| Date: | 2004 - 2025 |
| Title: | Biochemical Pharmacology Studies of Anvirzel and Related Natural Products |
| Funding Source: | Phoenix Biotechnology |
| Role: | PI |
| ID: | LS2004 00012124HM 01 |
| Title: | Targeting HCC Cancer Stem Cells |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
Selected Publications
Peer-Reviewed Articles
- Robinson JD, Cui Y, Karam-Hage M, Blalock JA, Shete S, Kypriotakis G, Yang P, Cinciripini PM. Standardized research electronic cigarette acceptability among adult men and women who smoke combustible cigarettes. Psych of Addictive Behaviors. e-Pub 2025. PMID: 41051837.
- Zuo X, Kiyasu Y, Liu Y, Deguchi Y, Liu F, Moussalli M, Tan L, Wei B, Wei D, Yang P, Shureiqi I. Colorectal 15-Lipoxygenase-1 as a Host Factor Determining the Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Colorectal Tumorigenesis in Mice. CMGH 19(12), 2025. PMID: 40818741.
- Cohen, L, Delorme, A, Cusimano, A, Chakraborty Patra, S, Nguyen, P, Deng, D, Iqbal, S, Nelson, M, Wei, D, Fields, C, Yang, P. Examining the effects of biofield therapy through simultaneous assessment of electrophysiological and cellular outcomes. Scientific reports 14(1), 2024. e-Pub 2024. PMID: 39622875.
- Chakraborty Patra, S, Wei, D, Tran, M, Lang Jr, FF, Newman, RA, Yang, P. PBI-05204, a supercritical CO2 extract of Nerium oleander, suppresses glioblastoma stem cells by inhibiting GRP78 and inducing programmed necroptotic cell death. Neoplasia (United States) 54, 2024. e-Pub 2024. PMID: 38823209.
- Gouda MA, Shunyakova J, Naing A, Dumbrava E, Hong DS, Yuan Y, Yang P, Myers A, Liang Y, Peng J, Karp D, Tsimberidou AM, Rodon J, Yap TA, Piha-Paul SA, Meric-Bernstam F, Fu S. A phase I study of TAK-659 and paclitaxel in patients with taxane-refractory advanced solid tumors. ESMO Open. e-Pub 2024. PMID: 38914452.
- Fields, C, Cohen, L, Cusimano, A, Chakraborty Patra, S, Nguyen, P, Deng, D, Iqbal, S, Nelson, M, Wei, D, Delorme, A, Yang, P. Search for Entanglement between Spatially Separated Living Systems. Biophysica 4(2):168-181, 2024. e-Pub 2024.
- Cohen L, Danhauer SC, Garcia M, Dressler EV, Rosenthal DI, Chambers MS, Cusimano A, Brown W, Ochoa JM, Yang P, Chiang JS, Gordon O, Crutcher R, Kim JK, Russin MP, Lukenbill J, Porosnicu M, Yost KJ, Weaver KE, Lesser GJ. Acupuncture for Chronic Radiation-Induced Xerostomia in Head and Neck Cancer. JAMA Netw Open. e-Pub 2024. PMID: 38739392.
- Wei, D, Wang, L, Liu, Y, Hafley, M, Tan, L, Lorenzi, PL, Yang, P, Zuo, X, Bresalier, R. Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression. Digestive diseases and sciences 68(7):3043-3058, 2023. e-Pub 2023. PMID: 37071246.
- Zhang, CC, Liu, SY, Liu, J, Yang, P, Lin, HS, Zhang, Y. Lung cancer treatment in traditional chinese medicine. World Journal of Traditional Chinese Medicine 9(3):297-306, 2023. e-Pub 2023.
- Wei, D, Chen, D, Mou, H, Chakraborty Patra, S, Wei, B, Tan, L, Lorenzi, PL, Qian, X, Yang, P. Targeting Glutamine Metabolism with a Novel Naþ/Kþ-ATPase Inhibitor RX108 in Hepatocellular Carcinoma. Molecular cancer therapeutics 22(6):693-705, 2023. e-Pub 2023. PMID: 36780187.
- Shatat MA, Gauthier B, Yoon S, Yuan E, Yang P, Narla G, Dowlati A, Lee RT. Mistletoe Lectin Inhibits Growth of Myc-amplified Small Cell Lung Cancer. Cancer Med. e-Pub 2023. PMID: 36562288.
- Narayanan S, Rozman de Mores A, Cohen L, Anwar M, Lazar F, Hicklen R, Lopez G, Yang P, Bruera E. Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Current Oncology Reports, 2023. e-Pub 2023.
- Wei D, Chen D, Mou H, Chakraborty S, Wei B, Tan L, Lorenzi P, Qian X, Yang P. Targeting Glutamine Metabolism with a Novel Na+/K+-ATPase Inhibitor RX108 in Hepatocellular Carcinoma. Molecular Cancer Therapeutics. e-Pub 2023.
- Gunther, J, Chadha, AS, Guha, S, Raju, GS, Maru, DM, Munsell, M, Jiang, Y, Yang, P, Felix, E, Clemons, M, Mathew, GG, Singh, PK, Skibber, JM, Rodriguez-Bigas, MA, Chang, GJ, Eng, C, Delclos, ME, Crane, C, Das, P, Krishnan, S. A phase II randomized double blinded trial evaluating the efficacy of curcumin with pre-operative chemoradiation for rectal cancer. Journal of Gastrointestinal Oncology 13(6):2938-2950, 2022. e-Pub 2022. PMID: 36636059.
- Vaccaro, S, Rossetti, A, Porrazzo, A, Camero, S, Cassandri, M, Pomella, S, Tomaciello, M, Macioce, G, Pedini, F, Barillari, G, Marchese, C, Rota, R, Cenci, G, Tombolini, M, Newman, RA, Yang, P, Codenotti, S, Fanzani, A, Megiorni, F, Festuccia, C, Minniti, G, Gravina, GL, Vulcano, F, Milazzo, L, Marampon, F. The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo. Frontiers in Pharmacology 13, 2022. e-Pub 2022. PMID: 36532747.
- Epner M, Yang P, Wagner R, Cohen L. Understanding the Link Between Sugar and Cancer: An Examination of the Preclinical and Clinical Evidence. Cancers, 2022. e-Pub 2022.
- Vaccaro S, Rossetti A, Porrazzo A, Camero S, Cassandri M, Pomella S, Tomaciella M, Macioce G, Pedini F, Barillari G, Marchese C, Rota R, Cenci G, Tombolini M, Newman R, Yang P, Codenotti S, Fanzani A, Megiorni F, Festuccia C, Minniti G, Gravina G, Vulcano F, Milazzo L, Marapon F. The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo. Frontiers in Pharmacology, 2022. e-Pub 2022.
- Shatat M, Gauthier B, Yoon S, Yuan E, Yang P, Narla G, Dowlati A, Lee R. Mistletoe lectin inhibits growth of Myc-amplified small-cell lung cancer. Cancer medicine 12(7):8378-8387, 2022. e-Pub 2022. PMID: 36562288.
- Yang P, Zuo X, Advani S, Wei B, Malek J, Day RS, Shureiqi I. Celecoxib Colorectal Bioavailability and Chemopreventive Response in Familial Adenomatous Polyposis Patients. Cancer Prev Res (Phila) 15(4):217-224, 2022. e-Pub 2021. PMID: 34610992.
- Colapietro A, Yang P, Rossetti A, Mancini A, Vitale F, Chakraborty S, Martellucci S, Marampon F, Mattei V, Gravina G, Iorio R, Newman R, Festuccia C. The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Is Synergistic with Radiotherapy in Models of Human Glioblastoma. Frontiers in Pharmacology 13, 2022. e-Pub 2022. PMID: 35401175.
- Bowers LW, Glenny EM, Bunjala A, Lanman NA, Goldbaum A, Himbert C, Montgomery SA, Yang P, Roper J, Ulrich CM, Dannenberg AJ, Coleman MF, Hursting SD. Weight loss and/or sulindac mitigate obesity-associated transcriptome, microbiome, and protumor effects in a murine model of colon cancer. Cancer Prev Res 15(8):481-495, 2022. e-Pub 2022. PMID: 35653548.
- Gunther J, Chadha A, Guha S, Raju G, Maru D, Munsell M, Jiang Y, Yang P, Felix E, Clemons M, Mathew G, Singh P, Skibber J, Rodrigues-Bigas M, Chang G, Eng C, Delclos M, Crane C, Das P, Krishnan S. A phase II randomized double blinded trial evaluating the efficacy of curcumin with pre-operative chemoradiation for rectal cancer. Journal of Gastrointestinal Oncology, 2022. e-Pub 2022.
- Bui D, Yin T, Duan S, Wei B, Yang P, Wong SJ, You M, Singh R, Hu M. Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer. J Nat Prod 84(9):2486-2495, 2021. e-Pub 2021. PMID: 34463097.
- Cata JP, Patiño M, Lacagnina MJ, Li J, Gorur A, Agudelo-Jimenez R, Wei B, Hagberg CA, Dougherty PM, Shureiqi I, Yang P, Grace PM. A rat model to investigate quality of recovery after abdominal surgery. Pain Rep 6(2):e943, 2021. e-Pub 2021. PMID: 34235345.
Review Articles
- Narayanan, S, de Mores, AR, Cohen, L, Anwar, MM, Lazar, F, Hicklen, RS, Lopez, G, Yang, P, Bruera, E. Medicinal Mushroom Supplements in Cancer. Current oncology reports 25(6):569-587, 2023. e-Pub 2023. PMID: 36995535.
- Epner, M, Yang, P, Wagner, R, Cohen, L. Understanding the Link between Sugar and Cancer. Cancers 14(24), 2022. e-Pub 2022. PMID: 36551528.
Other Articles
- Cohen, L, Delorme, A, Cusimano, A, Chakraborty Patra, S, Nguyen, P, Deng, D, Iqbal, S, Nelson, M, Wei, D, Fields, C, Yang, P Author Correction. Scientific reports 15(1), 2025. PMID: 40113910.
- Bresalier RS, Shaheen NJ, Hernandez M, Buttar N, Marcon N, Wani S, Muthusamy R, Falk G, Johnson TT, Yang P, Huo X, Castille TA, Della'Zanna G, Richmond E, Lee J, Brown P, Souza R Effect of Aspirin on Biomarkers of Barrett’s Esophagus After Successful Eradication with Radiofrequency Ablation. Dig Dis Sci. PMID: 39934623.
- Cohen L, Delorme A, Cusimano A, Chakraborty S, Nguyen P, Deng D, Iqbal S, Nelson M, Wei D, Fields C, Yang P Examining the effects of biofieldtherapy through simultaneousassessment of electrophysiologicaland cellular outcomes. Scientific Reports.
- Subbaramaiah, K, Howe, LR, Zhou, XK, Yang, P, Hudis, C, Kopelovich, L, Dannenberg, AJ Erratum. Cancer Prevention Research 15(6):411, 2022. PMID: 35652223.
- Subbaramaiah, K, Howe, LR, Bhardwaj, P, Du, B, Gravaghi, C, Yantiss, RK, Zhou, XK, Blaho, VA, Hla, T, Yang, P, Kopelovich, L, Hudis, C, Dannenberg, AJ Erratum. Cancer Prevention Research 15(6):413, 2022. PMID: 35652231.
Abstracts
- Colapietro A, Yang P, Rosetti A, Mancini A, Vital F, Martellu S, Marampon F, Matte V, Gravina GL, Newman RA, Festuccia C. The botanical drug PBI-05204, a supercritical CO₂ extract of Nerium oleander, augments the antitumor efficacy of radiotherapy in treatment of human glioblastoma. Cancer Res 82(12):6307, 2022. e-Pub 2022.
- Chakraborty S, Wei DY, and Yang P. PBI-05204, a supercritical CO2 extract of Nerium Oleander, suppresses the stemness of glioblastoma stem cells and inhibits Shh-Gli1-NANOG axis. Cancer Res 82(12):5075, 2022. e-Pub 2022.
- Chakraborty S, Zuo X, Hedge V, Tran M, Jiang Y, Wei B, Gagea M, Sastry J, Yang P. Dietary sugar promotes breast tumorigenesis partially through upregulating 12 lipoxygenase/PPARd signaling and remodeling breast tumor microenvironment. Cancer Res 82(12):5954, 2022. e-Pub 2022.
- Yang P, Chakraborty S, Nguyen P, Cui M, Cusimano A, Wei DY, Sarah Prinsloo S, and Cohen L. Biofield therapy suppressed the growth of human pancreatic cancer cells by modulation of cell cycle and cell voltage potentials. Cancer Res 82(12):5382, 2022. e-Pub 2022.
- Wei DY, Wang L, Liu Y, Hafley MA, Tan L, Lorenzi PL, Yang P, Zuo X, and Bresalier RS. Activation of vitamin D/VDR signaling reverses gemcitabine resistance of pancreatic cancer cells through inhibition of MUC1 expression. Cancer Res 82(12):6367, 2022. e-Pub 2022.
- Rubinstein A, Yang J, Martin R, Kingsley C, Cerda J, Michel K, Zhang J, Tailor R, Pan T, Yang P, Hazle J, Court L. Respiratory Motion Management for High-Precision Small Animal Irradiation. AACR proceeding, 2013. e-Pub 2013.
- Pirman D, Menter D, Efuet E, Yang P. MALDI mass spectrometric imaging reveals differential lipid metabolism in cancer. 60 ASMS Conference Proceeding, 2012. e-Pub 2012.
Book Chapters
- Newman, RA, Felix, E, Pang, J, Yang, P, Madden, T. Analysis of bioactive lipids by LC/MS/MS –free fatty acid and their methyl esters. In: HPLC of Acyl Fatty Acids. HNB, 473-498, 2005.
- St Pyrek J, Aggarval SK, Barboza P, Goodman JP, Yang PY. Metabolites of nuatigenin ((22S,25S)22,25-epoxy-3-beta,26-dihydroxy-furost-5-ene) accumulate in the bile of rabbits fed oats. In: Adv Exp Med Biol. Plenum Press, 443-458, 1996.
- Du Y, Li XN, Yang P, Newman RA. A role for cardiac glycosides in GBM therapy. In: Glioblastoma – Current Evidences.
Patents
- Liu Z, Yang P, Newman RA. Sweet gum fruit extract as a therapeutic agent. Patent Number: 60/939,143.
- Hassan JM, Yang P. Method for treating cancer. Patent Number: 10,751,376.
- Collin P, Yang P, Newman RA. Method to inhibit lipoxygenase and cancer cell proliferation. Patent Number: 60/194, 863.
- Method of determining the probability of a therapeutic response in cancer therapy with cardiac glycoside. Patent Number: 20130324485.
- A natural composition for anti-angiogenesis and anti-obesity. Patent Number: 12/761,798.
- Compositions and Methods for Modulating Lipid Composition. Patent Number: 15170548.0-1456.
- Method for treating oral cancers with herbal compositions. Patent Number: 7,744,931.
- Natural Composition to Decrease Effects of a High Fat Diet. Patent Number: 9,072,762.
Patient Reviews
CV information above last modified March 12, 2026