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      Pramod N. Nehete Image

      Pramod N. Nehete, PHD

      Department of Comparative Medicine, Division of Discovery Science

      About Dr. Pramod N. Nehete

      Dr. Nehete's research program is translational and directly applicable to improvement of human health using nonhuman primates as a model.  His research program in cellular immunology and vaccine development includes a range of diversified projects in which he actively collaborates with faculty from within the department and institution and outside of the institution.  Dr. Nehete's research focuses on mucosal immune responses and identifying suitable adjuvants for use in vaccine/therapeutics against infectious agents such as human immunodeficiency virus (HIV), Polyomavirus and Zika virus.  His research interest is using a novel nanochannel system for sustained delivery and studying of innate immunity stimulation via TLR9 on cerebral amyloid angioplasty using nonhuman primates.  Dr. Nehete has over twenty years of experience working in the area of vaccine development employing various animal models including nonhuman primate models.
      Read More

      Present Title & Affiliation

      Primary Appointment

      Professor, Comparative Medicine, Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, Bastrop, TX

      Associate Member, Comparative Medicine, The University of Texas MD Anderson Cancer Center, Bastrop, TX

      Education & Training

      Degree-Granting Education

      1989University of Poona, Pune, IN, Ph.D. in Biochemistry
      1978G.B. Pant University of Agriculture and Technology, Pantnager, IN, M.S. in Biochemistry
      1975Vikram University, Ujjain, IN, BS in Biology/Chemistry

      Postgraduate Training

      1975-1977Graduate Research Assistant, G.B. Pant University of Agriculture and Technology, Pantnager

      Experience & Service

      Faculty Academic Appointments

      Associate Professor, Comparative Medicine, Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, Bastrop, TX, 2006 - 2020

      Assistant Professor, Comparative Medicine, Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, Bastrop, TX, 1995 - 2006

      Not specified, Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1993 - 1995

      Not specified, Sarabhai Research Center, Baroda, 1978 - 1990

      Editorial Activities

      Editor, AIDS Research and Treatment, 2017 - Present

      Editor, Journal of Sexually Transmitted Diseases, 2012 - Present

      Honors & Awards

      1975 - 1977Fellowship, Center for Scientific and Industrial Research (CSIR)
      1972 - 1975National Scholarship, Government of India

      Professional Memberships

      American Association of Immunologists

      1997 - Present

      American Association for Advancement of Science

      1995 - Present

      Grant & Contract Support

      Date: 2022 - 2027
      Title:Innate Immunity Stimulation Effects on Biomarkers, Cognition and the Vascular Amyloid Proteome in a Squirrel Monkey Model of Sporadic CAA
      Funding Source:NIH/NCI
      Role:CO-I
      Date: 2022 - 2027
      Title:Cancer Immune-Interception in a Spontaneous Non-Human Primate Model of Lynch Syndrome
      Funding Source:NIH/NCI
      Role:Collaborator
      Date: 2022 - 2027
      Title:Ultra-Long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure
      Funding Source:NIH/NCI
      Role:Co-PI
      ID:1R01AI165372-01A1

      Selected Publications

      Peer-Reviewed Articles

      1. Nehete, PN, Nehete, BP, Chitta, S. Virus Protein-Specific Immune Responses in Selective Depletion of Lymphocyte Populations Using Monoclonal Antibodies in Bolivian Squirrel Monkeys (Saimiri boliviensis boliviensisv). Viral Immunology 38(1):12-22, 2025. e-Pub 2025. PMID: 39745246.
      2. Mulholland MM, Nehete BP, DeLise A, Achorn AM, Pytka LM, Nehete PN. Age-associated alterations in immune and inflammatory responses in captive olive baboons (Papio anubis). Front Aging, 2025. e-Pub 2025.
      3. Chitta, S, Nehete, BP, DeLise, A, Simmons, JH, Nehete, PN. Reactivity of HLADR antibody manifests expression of surface MHC II molecules on peripheral blood T lymphocytes in new world monkeys. Immunity, inflammation and disease 12(6), 2024. e-Pub 2024. PMID: 38923761.
      4. Pons-Faudoa, FP, Di Trani, N, Capuani, S, Facchi, I, Wood, AM, Nehete, BP, DeLise, A, Sharma, S, Shelton, K, Bushman, LR, Chua, CX, Ittmann, MM, Kimata, JT, Anderson, PL, Nehete, PN, Arduino, RC, Grattoni, A. Antiviral potency of long-acting islatravir subdermal implant in SHIV-infected macaques. Journal of Controlled Release 366:18-27, 2024. e-Pub 2024. PMID: 38142963.
      5. Mulholland, MM, Nehete, BP, DeLise, A, Achorn, AM, Pytka, LM, Nehete, PN. Age-associated alterations in immune and inflammatory responses in captive olive baboons ( Papio anubis). Frontiers in Aging 5:1511370, 2024. e-Pub 2024.
      6. Nehete, BP, DeLise, A, Nehete, PN. Identification of Specific Cell Surface Markers on Immune Cells of Squirrel Monkeys (Saimiri sciureus). Journal of immunology research 2024, 2024. e-Pub 2024. PMID: 38566886.
      7. Chitta S, Nehete BP, DeLise AB, Simmons JH, Nehete PN. Reactivity of HLADR antibody manifests expression of surface MHC II molecules on peripheral blood T lymphocytes in new world monkeys. Inflammation and Disease 12(6):e1318, 2024. e-Pub 2024.
      8. Nehete BP, DeLise A, Nehete PN. Identification of specific cell surface markers on immune cells of Squirrel Monkeys (Saimiri sciureus). Immunol Res:8215195, 2024. e-Pub 2024.
      9. Nehete PN, Nehete BP, Chitta S. Virus protein-specific immune responses in selective depletion of lymphocyte populations using monoclonal antibodies in Bolivian squirrel monkeys (Saimiri boliviensis bolieviensis). Viral Immunol, 2024. e-Pub 2024.
      10. Pons-Faudoa FP, Di Trani N, Capuani S, Campa-Carranza JN, Nehete B, Sharma S, Shelton KA, Bushman LR, Abdelmawla F, Williams M, Roon L, Nerguizian D, Chua CYX, Ittmann MM, Nichols JE, Kimata JT, Anderson PL, Nehete PN, Arduino RC, Grattoni A. Long-acting refillable nanofluidic implant confers protection against SHIV infection in nonhuman primates. Sci Transl Med 15(702), 2023. e-Pub 2023.
      11. Pons-Faudoa FP, Di Trani N, Capuani S, Hernandez N, Wood AM, Nehete B, Niles J, Shelton KA, Kezar S, Bushman LR, Chua CYX, Ittmann MM, Anderson PL, Nehete PN, Arduino RC, Nichols JE, Grattoni A. Changes in local tissue microenvironment in response to subcutaneous long-acting delivery of tenofovir alafenamide in rats and non-human primates. J Control Release 358(358):116-127, 2023. e-Pub 2023. PMID: 37120032.
      12. Pons-Faudoa, FP, Trani, ND, Capuani, S, Campa-Carranza, JN, Nehete, BP, Sharma, S, Shelton, K, Bushman, LR, Abdelmawla, F, Williams, M, Roon, L, Nerguizian, D, Chua, CX, Ittmann, MM, Nichols, J, Kimata, JT, Anderson, PL, Nehete, PN, Arduino, RC, Grattoni, A. Long-acting refillable nanofluidic implant confers protection against SHIV infection in nonhuman primates. Science translational medicine 15(702), 2023. e-Pub 2023. PMID: 37379369.
      13. Di Trani N, Pons-Faudoa FP, Sizovs A, Shelton KA, Marzinke MA, Nehete PN, Grattoni A. Extending drug release from implants via transcutaneous refilling with solid therapeutics. Adv Ther, 2022. e-Pub 2022. PMID: 35815229.
      14. Paez-Mayorga J, Campa-Carranza JN, Capuani S, Hernandez N, Liu H, Chua C, Pons-Faudoa F, Malgir G, Alvarez B, Niles J, Argueta L, Shelton K, Kezar S, Nehete P, Berman D, Willman M, Li X, Ricordi C, Nichols J, Gaber A, Kenyon N, Grattoni A. Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats. Nat Commun 13(1):7951, 2022. e-Pub 2022. PMID: 36572684.
      15. Patel AG, Karimi S, Nehete PN, Nehete BP, Murray S, Levine DT, Soliman MT, Llanos M, Hopkins WD, Williams LE, Wisniewski T, Scholtzova H. Chronic treatment study using class C CpG ODN in aged nonhuman primate model of sporadic CAA (Saimiri boliviensis boliviensis). Alzheimer's Dement 18, 2022. e-Pub 2022.
      16. Khuroo T, Dharani S, Mohamed E, Immadi S, Wu Z, Khan M, Lu D, Nehete P, Rahman Z. Ultra-long acting prodrug of dolutegravir and delivery system - Physicochemical, pharmacokinetic and formulation characterizations. Int J of Pharm 607, 2021. e-Pub 2021.
      17. Patel AG, Nehete PN, Krivoshik SR, Pei X, Cho EL, Nehete BP, Ramani MD, Shao Y, Williams LE, Wisniewski T, Scholtzova H. Innate immunity stimulation via CpG oligodeoxynucleotides ameliorates Alzheimer's disease pathology in aged squirrel monkeys. Brain 144(7):2146-2165, 2021. e-Pub 2021. PMID: 34128045.
      18. Pons-Feudoa FP, Sizovs A, Shelton KA, Momin Z, Niles JA, Bushman LR, Xu J, Chua CYX, Nichols JE, Demaria S, Ittmann MM, Hawkins T, Rooney JF, Marzinke MA, Kimata JT, Anderson PL, Nehete PN, Arduino RC, Ferrari M, Sastry KJ, Grattoni A. Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV-challenged nonhuman primates. Adv Ther 4(3), 2021. e-Pub 2021. PMID: 33997267.
      19. Genovese TS, Ramadane D, Kingsley C, Nehete PN, Patel AG, Leung J, Tibensky M, Rusinek H, Gray SB, Williams LE, Zaim-Wadghiri Y, Wisniewski T, Scholtzova H. MRI longitudinal and cross-sectional monitoring of amyloid pathology in non-human primates. Alzheimer's Dement(17), 2021. e-Pub 2021.
      20. Patel AG, Nehete PN, Nehete BP, Karimi SG, Genovese TS, Debure L, Drittel BD, Guttman DE, Williams LE, Wisniewski T, Scholtzova H. Evaluation of Class C CpG ODN efficacy and safety profile in a squirrel monkey model of AD pathology. Alzheimer's Dement 17, 2021. e-Pub 2021.
      21. Pons-Faudoa F, Trani N, Sizovs A, Shelton K, Momin Z, Bushman L, Xu J, Lewis D, Demaria S, Hawkins T, Rooney J, Marzinke M, Kimata J, Anderson P, Nehete P, Arduino R, Sastry K, Grattoni A. Viral Load Reduction in SHIV-Positive Nonhuman Primates via Long-Acting Subcutaneous Tenofovir Alafenamide Fumarate Release from a Nanofluidic Implant. Pharmaceutics 12(10):1-16, 2020. e-Pub 2020. PMID: 33080776.
      22. Paez-Mayorga J, Capuani S, Farina M, Lotito ML, Niles JA, Salazar HF, Rhudy J, Esnaola L, Chua CYX, Taraballi F, Corradetti B, Shelton KA, Nehete PN, Nichols JE, Grattoni A. Enhanced in vivo vascularization of 3D printed cell encapsulation device using platelet-rich plasma and mesenchymal stem cells. Adv Healthc Mater, 2020. e-Pub 2020. PMID: 32864893.
      23. Sizovs A, Pons-Faudoa F, Malgir G, Shelton K, Bushman L, Chau C, Anderson P, Nehete P, Sastry K, Grattoni A. Trans-urocanic acid enhances tenofovir alafenamide stability for long-acting HIV applications. Int J Pharm 587, 2020. e-Pub 2020. PMID: 32663582.
      24. Paez-Mayorga, J, Capuani S, Farina M, Lotito, ML, Niles JA, Salazar HF, Rhudy J, Esnaola L, Taraballi F, Corradetti B, Shelton K, Nehete PN, Nichols JE, Grattoni A. Enhanced In Vivo Vascularization of 3D‐Printed Cell Encapsulation Device Using Platelet‐Rich Plasma and Mesenchymal Stem Cells. Adv Healthcare Materials, 2020. e-Pub 2020.
      25. Magden ER, Nehete BP, Chitta S, Williams LE, Simmons JH, Abee CR, Nehete PN. Comparative analysis of cellular immune responses in conventional and SPF olive baboons (Papio anubis). Comp Med 70(2):160-169, 2020. e-Pub 2020. PMID: 32014083.
      26. Nehete PN, Williams LE, Chitta S, Nehete BP, Patel AG, Ramani MD, Wisniewski T, Scholtzova H. Class C CpG oligodeoxynucleotide immunomodulatory response in aged squirrel monkey (Saimiri Boliviensis Boliviensis). Front Aging Neurosci:12-36, 2020. e-Pub 2020. PMID: 32194391.
      27. Pons-Faudoa F, Sizovs A, Shelton K, Momin Z, Niles J, Bushman L, Xu J, Chua C, Nichols J, Demaria S, Ittmann M, Hawkins T, Rooney J, Marzinke M, Kimata J, Anderson P, Nehete P, Arduino R, Ferrari M, Sastry KJ, Grattoni A. Preventive Efficacy of a Tenofovir Alafenamide Fumarate Nanofluidic Implant in Shiv-Challenged Nonhuman Primates. Advtherap, 2020. e-Pub 2020.
      28. Genovese TS, Ramadane D, Kingsley C, Nehete PN, Nehete BP, Patel AG, Rusinek H, Williams LE, Zaim-Wadghiri Y, Wisniewski T, Scholtzova H. Neuroimaging of amyloid pathology in a nonhuman primate model of sporadic CAA. Alzheimer's Dement 16, 2020. e-Pub 2020.
      29. Shelton KA, Nehete BP, Chitta S, Williams LE, Schapiro SJ, Simmons J, Abee CR, Nehete PN. Effects of transportation and relocation on immunologic measures in cynomolgus macaques (Macaca fascicularis). J Am Assoc Lab Ani Sci 58(6):774-782, 2019. e-Pub 2019. PMID: 31604484.
      30. Matchett WE, Anguiano-Zarate SS, Nehete PN, Shelton K, Nehete BP, Yang G, Haigwood NL, Sastry JK, Barry MA. Divergent HIV-1-directed immune responses generated by systemic and mucosal immunization with replicating single-cycle adenoviruses in rhesus macaques. Journal of Virology 93(10), 2019. e-Pub 2019. PMID: 30842321.
      31. Couturier J, Orozco AF, Liu H, Budhiraja S, Siwak EB, Nehete PN, Sastry JK, Rich AP, Lewis DE. Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells. Virology Journal 16(1):22, 2019. e-Pub 2019. PMID: 30786885.
      32. Milich KM, Koestler BJ, Simmons JH, Nehete PN, DiFiore A, Williamsw LE, Dudley JP, Vanchiere J, Payne SM. Methods for detecting Zika virus in feces: A case study in captive squirrel monkeys (Saimiri boliviensis boliviensis). PLoS One 13(12), 2018. e-Pub 2018. PMID: 30571742.
      33. Nehete PN, Wilkerson GK, Nehete BP, Chitta S, Ruiz JC, Scholtzova H, Williams LE, Abee CR, Vanchiere JA. Cellular Immune Responses in Peripheral Blood Lymphocytes of Giardia Infected Squirrel Monkey (Saimiri boliviensis boliviensis) Treated with Fenbendazole. PLoS One 13(11), 2018. e-Pub 2018. PMID: 30412580.
      34. Chua C, Jain P, Ballerini A, Bruno G, Hood R, Gupte M, Gao S, DiTrani N, Susnjar A, Shelton K, Bushman L, Folci M, Filguerira C, Marzinke M, Anderson P, Hu M, Nehete P, Arduino R, Grattoni A. Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis. J Control Release 286:315-325, 2018. e-Pub 2018. PMID: 30092254.
      35. Anguiano-Zarate SS, Matchett WE, Nehete P, Sastry JK, Marzi A, Barry MA. A replicating single-cycle adenovirus vaccine against ebola virus. J Infect Dis, 2018. e-Pub 2018. PMID: 29982595.
      36. Filgueira CS, Bruno G, Smith ZW, Chua CYX, Ballerini A, Folci M, Gilbert AL, Jain P, Sastry JK, Nehete PN, Shelton KA, Hill LR, Ali A, Youker KA, Grattoni A. Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study. Biomed Microdevices, 2018. e-Pub 2018. PMID: 29916059.
      37. Gurung S, Dubaut JP, Nadeau H, Hyatt K, Reuter N, Nehete B, Wolf RF, Nehete P, Dittmer DP, Myers DA, Papin JF. Translational model of zika virus disease in baboons. J Virol, 2018. e-Pub 2018. PMID: 29875247.
      38. Couturier J, Winchester LC, Suliburk JW, Wilkderson GK, Podany AT, Agarwal N, Xuan Chua CY, Nehete PN, Nehete BP, Grattoni A, Sastry JK, Fletcher CV, Lake JE, Balasubramanyan A, Lewis DE. Adipocytes impair efficacy of antiretroviral therapy. Antiviral Res 154:140-148, 2018. e-Pub 2018. PMID: 29630975.
      39. Nehete PN, Abee CR, Wilkerson GK, Weaver SC, Brady AG, Vasilakis N, Roundy CM, Baze WB, Williams LW, Azar SR, Ruiz JC, Vanchiere JA, McClure GB, Keuhl TJ, Rossi SL, Simmons JH, Rogers DL. Experimental Zika Virus Infection of Neotropical Primates. Am J Trop Med Hyg 98(1):173-177, 2018.
      40. Dorta-Estremera S, Nehete PN, Yang G, He H, Nehete BP, Shelton KK, Barry MA, Sastry KJ. Minimally invasive monitoring of CD4 T cells at multiple mucosal tissues after intranasal vaccination in rhesus macaques. PLoS One 8(12), 2017. e-Pub 2017. PMID: 29220358.
      41. Vanchiere JA, Ruiz JC, Brady AG, Kuehl TJ, Williams LE, Baze WB, Wilkerson GK, Nehete PN, McClure GB, Rogers DL, Rossi SL, Azar SR, Roundy CM, Weaver SC, Vasilakis N, Simmons JH, Abee CR. Experimental Zika Virus Infection of Neotropical Primates. Am J Trop Med Hyg, 2017. e-Pub 2017. PMID: 29182145.
      42. Nehete PN, Magden ER, Nehete BP, Williams LE, Abee CR, Sastry KJ. Age- and Sex-associated Differences in Phenotypic and Functional Characteristics of Peripheral Blood Lymphocytes in Chimpanzees (Pan troglodytes). J Am Assoc Lab Anim Sci 56(5):509-519, 2017. e-Pub 2017. PMID: 28903821.
      43. Nehete PN, Nehete BP, Chitta S, Williams LE, Abee CR. Phenotypic and Functional Characterization of Peripheral Blood Lymphocytes from Various Age- and Sex-Specific Groups of Owl Monkeys (Aotus nancymaae). Comp Med 67(1):67-78, 2017. e-Pub 2017. PMID: 28222841.
      44. Couturier J, Agarwal N, Nehete PN, Baze WB, Barry MA, Sastry JK, Balasubramanyam A, Lewis DE. Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques. Retrovirology, 2016. e-Pub 2016. PMID: 27117277.

      Other Articles

      1. Nehete PN, Koestler BJ, Simmons JH, Nehete PN, Di Fiore A, Williams LE Methods for detecting Zika virus in feces: A case study in captive squirrel monkeys (Saimiri boliviensis boliviensis). PLoS One 13(12), 2018. PMID: 30571742.

      Abstracts

      1. Karimi S, Patel AG, Nehete PN, Debure L, Wang F, Botello RR, Chanine G, Zhang Q, Shao Y, Mulholland MM, Gray SB, Hopkins WD, Wisniewski T, Scholtzova H. Assessment of fluid biomarker profiles across disease continuum in a nonhuman primate model of sporadic CAA. Alzheimer's & Dementia 20(Suppl 2), 2024. e-Pub 2024.
      2. Patel AG, Soliman MT, Ficaro L, Nehete BP, Karimi S, Wang F, Kim H, Williams LE, Nehete PN, Jones DR, Wisniewski T, Scholtzova H. Assessment of the brain metabolome following innate immunity stimulation in a nonhuman primate model of sporadic CAA. Alzheimer's & Dementia 20(Suppl 2), 2024. e-Pub 2024.
      3. Patel AG, Karimi S, Nehete PN, Nehete BP, Murray S, Debure L, Soliman MT, Szabo J, Levine DT, Williams LE, Gray SB, Hopkins WD, Wisniewski T, Scholtzova H. Evaluation of biomarker, behavioral and immunostimulatory profiles following treatment with Class C CpG ODN in a nonhuman primate model of sporadic CAA. Alzheimer's & Dementia 19(S21), 2023. e-Pub 2023.
      4. Karimi S, Patel AG, Nehete BP, Nehete PN, Debure L, Levine DT, Cho O, Rami D, Soliman MT, Llanos M, Gray SB, Hopkins WD, Wisniewski T, Scholtzova H. Age-associated biomarker profiles in a nonhuman primate model of sporadic CAA. Alzheimers & Dementia 19(S21), 2023. e-Pub 2023.
      5. Patel A, Nehete PN, Salaymeh N, Nehete BP, Karimi S, Debure L, Zhang Q, Wang F, Pytka LM, Shao Y, Mulholland MM, Hopkins WD, Wisniewski T, Scholtzova H. Age-related changes in fluid biomarkers and cognitive abilities in a non-human primate model of AD pathology. AAIC Conference.
      6. Genovese TS, Ramadane D, Kingsley C, Nehete PN, Patel AG, Leung J, Tibensky M, Rusinek H, Gray SB, Williams LE, Zaim-Wadghiri Y, Scholtzova H. MRI longitudinal and cross-sectional monitoring of amyloid pathology in nonhuman primates. The 24th Alzheimer's Association International Conference.
      7. Patel AG, Nehete PN, Nehete BP, Karimi SG, Genovese TS, Debure L, Drittel BD, Guttman DE, Williams LE, Wisniewski T, Scholtzova H. Evaluation of Class C CpG ODN efficacy and safety profile in a squirrel monkey model of AD pathology. The 24th Alzheimer's Association International Conference.
      8. Salaymeh N, Karimi S, Patel A, Nehete PN, Nehete BP, Debure L, Wang F, Botello RR, Chahine G, Chen A, Zhang Q, Shao Y, Gray SB, Mulholland MM, Hopkins WD, Wisniewski T, Scholtzova H. Assessment of fluid biomarker profiles across disease continuum in a nonhuman primate model of sporadic CAA. NYU Neurology Symposium.
      9. Patel A, Soliman MT, Ficaro L, Nehete BP, Karimi S, Wang F, Kim H, Botello RR, Chahine G, Williams LE, Nehete PN, Jones DR, Wisniewski T, Scholtzova H. Assessment of the brain metabolome following innate immunity stimulation in a nonhuman primate model of sporadic CAA. NYU Neurology Symposium.
      10. Patel A, Nehete PN, Nehete BP, Salaymeh N, Karami S, Debure L, Wang F, Williams L, Mulholland MM, Hopkins WD, Wisniewski T, Scholtzova H. Evaluation of the efficacy and safety of TLR9 stimulation in a nonhuman primate model of sporadic cerebral amyloid angiopathy. IMMUNOLOGY2025.
      11. Salaymeh N, Patel A, Nehete PN, Nehete BP, Debure L, Wang F, Ryckman B, Pytka LM, Swain J, Hopkins WD, Mulholland MM, Wisniewski T, Scholtzova H. Innate immunity stimulation effects on biofluid/imaging biomarkers and cognition in a nonhuman primate model of sporadic AD pathology. AAIC Conference.

      Patents

      1. Use of a Composition Comprising a Peptide for the Inhibition of HIV. Patent Number: European Serial # 9911207.2107, 8/17/99. MDA87-009CIP4 EP. Patent # 671947.
      2. Compositions and Methods for Eliciting Immune or Anti-Infective Response (a) Enhancement and Systemic Spread of Virus-Specific CTL Responses Mediated by Mixtures of Helper T-Cell and CTL Inducing Peptides. Patent Number: US 7319000.
      3. Methods and Compositions for Eliciting Ctotoxic T-lymphocyte Responses Against Viruses. Patent Number: Australian Serial # 32339/93, filed 12/2/93. MDA87-009CIP4 AU Patent No. 666160.
      4. HIV-Specific T-Cell Induction. Patent Number: US SN 09/440,772, filed 1/16/99. MDA97-036 US. US Patent # 6656471 B1.
      5. HIV Specific T-Cell Induction. Patent Number: US 7,306,804,B2.
      6. Prophylaxis and Therapy of Acquired Immunodeficiency Syndrome. Patent Number: USSN 07/410,727, filed 9/20/89. MDA87-009 US CIP1, Patent # 5,128,319.
      7. CD4 Peptides for Binding to Viral Envelope Proteins. Patent Number: US SN: 08/115,171, Feb 18, 1997. MDA93-013 US. Patent # 5,603,933.
      8. Methods and Compositions for the Priming of Specific Cytoxic T-Lymphocyte Response. Patent Number: US SN 07/0800,932, filed 12/2/91. MDA87-009CIP2 US Patent # 6210,873 B1.
      9. HIV-Specific T-Cell Induction. Patent Number: Canadian counterpart patent application based on International Patent Application No. PCT/US99/27185 and US SN 60/0108,563 and 60/115,175, Patent no. 2,350,911.
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