Qing H. Meng, Ph.D.
Department of Laboratory Medicine, Division of Pathology-Lab Medicine Div
Present Title & Affiliation
Primary Appointment
Professor, Department of Laboratory Medicine, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, Department of Clinical Chemistry and Special Chemistry Laboratories, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, Department of Postdoctoral Clinical Chemistry Fellowship Program, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1999 | University of Helsinki, Helsinki, FIN, PHD, Medical Sciences |
| 1985 | Xuzhou Medical University, Jiangsu, CHN, MD, Medicine |
Postgraduate Training
| 2013-2014 | Faculty Leadership Academy, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2010-2011 | Leadership and Management Succession Program, Saskatoon Health Region, Saskatoon |
| 2001-2003 | Clinical Chemistry, Postdoctoral Training Program, McMaster University, Hamilton |
| 1999-2001 | Research Fellowship, Postdoctoral Training, University of Toronto, Toronto |
Board Certifications
| 2004 | American Board of Clinical Chemistry (Lifetime) |
| 2004 | Canadian Academy of Clinical Biochemistry |
Experience & Service
Academic Appointments
Director, Department of Pathology/Laboratory Medicine, Division of Clinical Biochemistry Laboratories, Royal University Hospital, Saskatoon Health Region, College of Medicine, University of Saskatchewan, Saskatoon, 2011 - 2012
Clinical Professor, Department of Pathology/Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, 2010 - 2011
Associate Director, Department of Pathology/Laboratory Medicine, Division of Clinical Biochemistry Laboratories, Royal University Hospital, Saskatoon Health Region, Saskatoon, 2008 - 2011
Clinical Associate Professor, Department of Pathology/Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, 2008 - 2010
Clinical Biochemist, Department of Pediatric Laboratory Medicine, Division of Pathology/Lab Medicine, The Hospital for Sick Children, Toronto, 2006 - 2008
Assistant Professor, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, 2006 - 2008
Assistant Professor, Department of Pathology/Laboratory Medicine, University of Saskatchewan, Saskatoon, 2003 - 2006
Clinical Biochemist, Department of Pathology/Laboratory Medicine, Royal University Hospital, Saskatoon Health Region, Saskatoon, 2003 - 2006
Administrative Appointments/Responsibilities
Postdoctoral Fellow / Clinical Chemistry Diploma Program, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, 2001 - 2003
Postdoctoral Fellow, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, 1999 - 2001
Ph.D. Candidate, Department of Departments of Medicine and Clinical Chemistry, Helsinki Central Hospital, Faculty of Medicine, University of Helsinki, Helsinki, 1995 - 1999
Research Associate, Department of Pharmacology and Toxicology, Faculty of Medicine, University of Helsinki, Helsinki, 1993 - 1995
Physician (medicine and cardiology), Department of Medicine, Second People's Hospital of Lianyungang, Jiangsu, 1987 - 1993
Pediatrician, Department of Pediatrics, Second People's Hospital of Lianyungang, Jiangsu, 1985 - 1987
Other Appointments/Responsibilities
Faculty, College of Graduate Studies, University of Saskatchewan, Saskatoon, 2004 - 2012
Honors & Awards
| 2017 | Clinical Chemist Recognition Award, AACC |
| 2015 | Clinical Chemist Recognition Award, AACC |
| 2014 | President's Recognition for Faculty Excellence, MD Anderson Cancer Center |
| 2014 | Patient Safety Abstract Award, AACC |
| 2013 | Research Excellence Award, CSCC |
| 2013 | Clinical Chemist Recognition Award, AACC |
| 2013 | Outstanding Speaker Award, AACC |
| 2012 | Excellence in Research and Best Abstract Award, AACC Nutrition Division |
| 2012 | Clinical Chemist Recognition Award, AACC |
| 2011 | Critical and Point-of-Care Testing Division and the Van Slyke Foundation Research Grant Award, AACC |
| 2011 | International Exchange Grant Award, CSCC |
| 2011 | Rocky Mountain Section Scholarship, AACC |
| 2010 | Clinical Chemist Recognition Award, AACC |
| 2008 | Best Poster Award, AACC Division of Animal Clinical Chemistry |
| 2008 | Distinguished Abstract Award (x2), NACB |
| 2008 | Saskatchewan Health Grants |
| 2007 | Clinical Chemist Recognition Award, AACC |
| 2006 | Distinguished Abstract Award, NACB |
| 2003 | Research Award, Dutkevich Memorial Trust Fund (McMaster University) |
| 2003 | Clinical Chemists Travel Award, Ontario Society |
| 2002 | Best Poster Award, Canadian Society of Clinical Chemists |
| 2002 | Clinical Chemists Award, Canadian Society |
| 1998 | Spring-light Shining Project Award, Ministry of Education of China |
| 1998 | Conference Travel Award, University of Helsinki |
| 1997 | Chancellor's Research Award, University of Helsinki |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Li J, Ma J, Wagar EA, Liang D, Meng QH. A rapid ultra-performance LC-MS/MS assay for determination of serum unbound fraction of voriconazole in cancer patients. Clin Chim Acta 486:36-41. e-Pub 2018. PMID: 30016626.
- Huang F, Chen Z, Chen H, Lu W, Xie S, Meng QH, Wu Y, Xia D. Cypermethrin Promotes Lung Cancer Metastasis via Modulation of Macrophage Polarization by Targeting MicroRNA-155/Bcl6. Toxicol Sci 163(2):454-465, 2018. PMID: 29471534.
- Bai F, Zhou H, Ma M, Guan C, Lyu J, Meng QH. A novel RNA sequencing-based miRNA signature predicts with recurrence and outcome of hepatocellular carcinoma. Mol Oncol 12(7):1125-1137, 2018. e-Pub 2018. PMID: 29719937.
- Genzen JR, Murray DL, Abel G, Meng QH, Baltaro RJ, Rhoads DD, Delgado JC, Souers RJ, Bashleben C, Keren DF, Ansari MQ. Screening and Diagnosis of Monoclonal Gammopathies: An International Survey of Laboratory Practice. Arch Pathol Lab Med 142(4):507-515, 2018. e-Pub 2017. PMID: 29266967.
- Wang JF, Pu X, Zhang X, Chen K, Xi Y, Wang J, Mao X, Zhang J, Heymach JV, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Meng QH, Shaw KR, Eterovic AK, Fang B. Variants with a low allele frequency detected in genomic DNA affect the accuracy of mutation detection in cell-free DNA by next-generation sequencing. Cancer 124(5):1061-1069, 2018. e-Pub 2017. PMID: 29178133.
- Cao L, Lee CH, Ning J, Handy BC, Wagar EA, Meng QH. Combination of prostate cancer antigen 3 and prostate-specific antigen improves diagnostic accuracy in men at risk of prostate cancer. Arch Pathol Lab Med. e-Pub 2018. PMID: 29547000.
- Booth RA, McCudden CR, Balion CM, Blasutig IM, Bouhtiauy I, Rodriguez-Capote K, Catomeris P, Chan PC, Chen Y, Collier C, Hauff K, Kalra J, Li D, Lin DC, Lou AH, Meng QH, Morrison T, Pasic MD, Qureshi M, Randell E, Sohn KY, Thakur V, Thomas D, Thoni A, Tomalty C, Yang L, Zamkanei M. Candidate recommendations for protein electrophoresis reporting from the Canadian Society of Clinical Chemists Monoclonal Gammopathy Working Group. Clin Biochem 51:10-20, 2018. e-Pub 2017. PMID: 29061378.
- Li C, Zheng X, Li W, Bai F, Lyu J, Meng QH. Serum miR-486-5p as a diagnostic marker in cervical cancer: with investigation of potential mechanisms. BMC Cancer 18(1):61, 2018. e-Pub 2018. PMID: 29316891.
- Li H, Meng QH, Noh H, Somaiah N, Torres KE, Xia X, Batth IS, Joseph CP, Liu M, Wang R, Li S. Cell-surface vimentin-positive macrophage-like circulating tumor cells as a novel biomarker of metastatic gastrointestinal stromal tumors. Oncoimmunology 7(5):e1420450, 2018. e-Pub 2018. PMID: 29721368.
- Li C, Lyu J, Meng QH. MiR-93 Promotes Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer Cells by Activating the PI3K/Akt Pathway via Inhibition of LKB1/PTEN/CDKN1A. J Cancer 8(5):870-879, 2017. e-Pub 2017. PMID: 28382150.
- Liu X, Meng QH, Ye Y, Hildebrandt MA, Gu J, Wu X. Prognostic significance of pretreatment serum levels of albumin, LDH and total bilirubin in patients with non-metastatic breast cancer. Carcinogenesis 36(2):243-248, 2015. e-Pub 2014. PMID: 25524924.
- Meng QH, Wagar EA. Pseudohyperkalemia: A New Twist on an Old Phenomenon. Crit Rev Clin Lab Sci 16(2):1-11, 2015. e-Pub 2014. PMID: 25319088.
- Meng QH, Wagar EA. Laboratory approaches for the diagnosis and assessment of hypercalcemia. Crit Rev Clin Lab Sci 20(3):1-13, 2015. e-Pub 2014. PMID: 25327435.
- Gan R, Yang Y, Yang X, Zhao L, Lu J, Meng QH.. Downregulation of miR-221/222 enhances sensitivity of breast cancer cells to tamoxifen through upregulation of TIMP3. Cancer Gene Ther 21(7):290-296, 2014. e-Pub 2014. PMID: 24924200.
- Meng QH, Wagar EA. Severe hypophosphatemia in a 79-year-old man. Clin Chem 60(7):928-931, 2014. PMID: 24973428.
- Meng QH, Handy B, Wagar E.. A Case of Green Blood. Clinical Chemistry 60(4):695-696, 2014. PMID: 24682689.
- Meng QH, Wagar EA.. An Unusual Case of Severe Hypophosphatemia. Clinical Chemistry 60:928-931, 2014.
- Meng QH, Xu E, Hildebrandt MA, Liang D, Lu K, Ye Y, Wagar EA, Wu X. Genetic variants in the fibroblast growth factor pathway as potential markers of ovarian cancer risk, therapeutic response, and clinical outcome. Clin Chem 60(1):222-232, 2014. e-Pub 2013. PMID: 24146310.
- Yang X, Yang Y, Gan R, Zhao L, Li W, Zhou H, Wang X, Lu J, Meng QH. Down-regulation of mir-221 and mir-222 restrain prostate cancer cell proliferation and migration that is partly mediated by activation of SIRT1. PLoS One 9(6):e98833, 2014. e-Pub 2014. PMID: 24892674.
- Chen M, Calin G, Meng QH.. Circulating microRNA as promising tumor biomarkers: opportunities and challenges for the clinical laboratory. Advances in Clinical Chemistry 67:189-214, 2014.
- Meng QH, Handy B, Wagar EA.. It's not easy being blue-green. Ann Lab Med 33(6):457-458, 2013. e-Pub 2013. PMID: 24205497.
- Estey MP, Cohen AH, Colantonio DA, Chan MK, Marvasti TB, Randell E, Delvin E, Cousineau J, Grey V, Greenway D, Meng QH, Jung B, Bhuiyan J, Seccombe D, Adeli K.. CLSI-based Transference of the CALIPER Database of Pediatric Reference Intervals from Abbott to Beckman, Ortho, Roche and Siemens Clinical Chemistry Assays: Direct Validation Using Reference Samples from the CALIPER Cohort. Clin Biochem 46(13-14):1197-1219, 2013. e-Pub 2013. PMID: 23578738.
- Bo J, Li W, Chen Z, Wadden DG, Randell E, Zhou H, Lu J, Meng QH.. D-lactate: a novel contributor to metabolic acidosis and high anion gap in diabetic ketoacidosis. Clin Chem 59(9):1406-1407, 2013. e-Pub 2013. PMID: 23836843.
- Meng QH, Handy B, Wagar EA.. Confirmatory Testing of Urine Ketones and Bilirubin: Still Necessary?. Arch Pathol Lab Med 137(8):1028-1029, 2013. PMID: 23899056.
- Wang Y, Chen Z, Chen J, Pan J, Zhang W, Pan Q, Ding H, Lin X, Wen X, Li Y, Meng Q.. The diagnostic value of apolipoprotein E in malignant pleural effusion associated with non-small cell lung cancer. Clin Chim Acta 421:230-235, 2013. e-Pub 2013. PMID: 23523589.
- Zhang J, Xie D, Zhou H, Fan R, Zhang L, Li C, Jin S, Meng QH, Lu J.. The -590C/T polymorphism in the IL-4 gene and the risk of cancer: a meta-analysis. Tumour Biology 34:2261-2268, 2013.
Editorials
- Meng QH. Mass Spectrometry Applications in Clinical Diagnostics. Journal of Clinical and Experimental pathology, 2013.
Grant & Contract Support
| Title: | The Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) |
| Funding Source: | Canadian Institute of Health Research (CIHR) |
| Role: | Co-Investigator |
| Title: | Zhejiang Provincial Natural Science Foundation ¥100,000 (CNY) |
| Funding Source: | Zhejiang Provincial Natural Science Foundation |
| Role: | Investigator |
| Title: | AACC Critical and Point-of-Care Testing Division and the Van Slyke |
| Funding Source: | AACC Critical and Point-of-Care Testing Division and the Van Slyke |
| Role: | Investigator |
| Title: | CALIPER: Closing the Gaps in Pediatric Reference Intervals |
| Funding Source: | Canadian Institute of Health Research (CIHR) |
| Role: | Co-Investigator |
| Title: | BioNEMS - Biological Nano Electrical Mechanical System |
| Funding Source: | Saskatchewan Health Research Foundation |
| Role: | Co-Investigator |
| Title: | Heart and Stroke Foundation of Canada |
| Funding Source: | Heart and Stroke Foundation of Canada (Ontario & Saskatchewan) |
| Role: | Investigator |
| Title: | Protective Role of Hydrogen Sulfide in Atherosclerosis |
| Funding Source: | Canada Foundation for Innovation (CFI) |
| Role: | Investigator |
| Title: | Role of H2S in Atherosclerosis and Thrombosis |
| Funding Source: | Saskatchewan Health Research Foundation |
| Role: | Investigator |
| Title: | Protective Role of H2S in the Development and Progression of Atherosclerosis and Stenosis |
| Funding Source: | Heart and Stroke Foundation of Canada (Saskatchewan) |
| Role: | Investigator |
| Title: | Royal University Hospital Foundation Fund |
| Funding Source: | Royal University Hospital Foundation |
| Role: | Co-Investigator |
| Title: | Establishment of Pediatric Reference on Roche Cobas System |
| Funding Source: | College of Medicine, University of Saskatchewan |
| Role: | Investigator |
| Title: | Royal University Hospital Foundation Fund |
| Funding Source: | Royal University Hospital Foundation |
| Role: | Investigator |
| Title: | Dean's Fund |
| Funding Source: | University of Toronto |
| Role: | Investigator |
| Title: | Start-up Operating Grant-Department of Laboratory Medicine and Pathobiology |
| Funding Source: | University of Toronto |
| Role: | Investigator |
| Title: | Charles Hollenberg Summer Studentship Program |
| Funding Source: | Banting and Best Diabetes Centre |
| Role: | Supervisor |
| Title: | Start-up Operation Grant |
| Funding Source: | Hospital for Sick Children |
| Role: | Investigator |
| Title: | Supplemental Capital Equipment Start-up Fund |
| Funding Source: | University of Saskatchewan |
| Role: | Investigator |
| Title: | Health Quality Council Innovation Fund |
| Funding Source: | Health Quality Council Innovation Fund (Saskatchewan) |
| Role: | Investigator |
| Title: | Royal University Hospital Foundation Innovation Fund |
| Funding Source: | Royal University Hospital Foundation |
| Role: | Investigator |
| Title: | Start-up Operation Grant |
| Funding Source: | University of Saskatchewan |
| Role: | Investigator |
| Title: | Start-up Operating Grant Capital Equipment |
| Funding Source: | University of Saskatchewan |
| Role: | Investigator |
| Title: | Start-up Operating Grant |
| Funding Source: | College of Medicine, University of Saskatchewan |
| Role: | Investigator |
| Title: | Chancellor's Research Grant |
| Funding Source: | University of Helsinki |
| Role: | Investigator |
| Title: | 350th Anniversary Foundation Grant |
| Funding Source: | University of Helsinki |
| Role: | Investigator |
| Title: | Chancellor's Research Grant |
| Funding Source: | University of Helsinki |
| Role: | Investigator |
| Title: | MD Anderson Start-Up Finds |
| Funding Source: | M D Anderson Cancer Center |
| Role: | Principal Investigator-MDACC |
| Title: | U54 Partnership for Excellence in Cancer Research |
| Funding Source: | National Cancer Institute (NCI) |
| Role: | Co-Investigator |
| Title: | Multivariate Prediction of Prostate Cancer in Puerto Rican and African American Men |
| Funding Source: | Beckman Coulter Grant |
| Role: | Co-Investigator |
| Title: | High Sensitivity Troponin T to monitor doxorubicin-induced cardiotoxicity (RD001857) |
| Funding Source: | Roche Diagnostic Grant |
| Role: | Co-Investigator |
Patient Reviews
CV information above last modified January 18, 2023