Qiong Gan, M.D., Ph.D

Peer-Reviewed Articles

1. Han, J, Ding, Y, Gan, Q, Sweeney, K, Huang, X, Hameed, N, Weissferdt, A, Wang, Y, Peng, Y, Sun, H. TRPS1 and GATA3 expression in BRG1/SMARCA4-deficient malignant neoplasms. Hum Pathol 177, 2026. e-Pub 2026. PMID: 42398545.
2. Gan Q. GATA3 and TRPS1 Expression in Follicular Dendritic Cell Sarcoma, 2026. e-Pub 2026. PMID: 42631924.
3. Yamashita, K, Kwiatkowski, E, Sewastjanow-Silva, M, Rogers, JE, Yoshimura, K, Pizzi, M, Gan, Q, Li, JJ, Waters, R, Murphy, MB, Iwatsuki, M, Hofstetter, WL, Chen, A, Yuan, Y, Ajani, JA. Clinical Machine Learning Model for Predicting Pathological Complete Response in Patients with Esophageal and Gastroesophageal Junction Adenocarcinoma After Trimodality Therapy. Ann Surg Oncol 33(8):7133-7141, 2026. e-Pub 2026. PMID: 42002713.
4. Fan, Y, Vykoukal, JV, Song, S, Pizzi, M, Zou, G, Yoshimura, K, Jin, J, Katayama, H, Calin, GA, Waters, R, Gan, Q, Wang, L, Hanash, S, Dhar, SS, Ajani, JA. Protocol for isolating patient-derived ascites cells and extracellular vesicles from gastric cancer peritoneal metastases. STAR Protocols 6(4), 2025. e-Pub 2025. PMID: 41105517.
5. Ahmed, MS, Klippel-Almaraz, D, Amin, SE, Sura, GH, Kundu, UR, Yu, W, Stewart, JM, Gan, Q, Krishnamurthy, S. Utility of whole-slide imaging for rapid evaluation of thyroid FNA. Cancer Cytopathology 133(9), 2025. e-Pub 2025. PMID: 40889104.
6. Song, S, Fan, Y, Zou, G, Huo, L, Kumar, J, Li, Y, Wang, R, Dai, E, Jin, J, Scott, AW, Shao, SH, Pizzi, M, Vykoukal, JV, Katayama, H, Hanash, S, Calin, GA, Zhang, X, Lee, MG, Wang, Z, Lo, Y, Gan, Q, Waters, R, Yin, F, Wang, L, Cheng, X, Ajani, JA, Dhar, SS. KAP1 promotes gastric adenocarcinoma progression by activating Hippo/YAP1 signaling via binding to HNRNPAB. Cancer Letters 621, 2025. e-Pub 2025. PMID: 40189014.
7. Thomas K, Trinh H, Fei A, Khazai L, Sun H, Gan QJ. Cytologic features of angiosarcoma in fluid specimens: A retrospective study of 22 cases. Cancer Cytopathol 133(3):e70004, 2025. e-Pub 2025. PMID: 39992713.
8. Yoshimura K, Zou G, Fan Y, Yamashita K, Wang L, Wu J, Wang R, Shao S, Scott AW, Jin J, Pizzi MP, Yao X, Brown CA, Wang L, Gan Q, Waters RE, Yin F, Song S, Dhar SS, Ajani JA. HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer. Cancer Lett 610:217354, 2025. e-Pub 2025. PMID: 39603381.
9. Fan Y, Song S, Pizzi MP, Zou G, Vykoukal JV, Yoshimura K, Jin J, Calin GA, Waters RE, Gan Q, Wang L, Hanash S, Dhar SS, Ajani JA. Exosomal Galectin-3 promotes peritoneal metastases in gastric adenocarcinoma via microenvironment alterations. iScience 28(1):111564, 2025. e-Pub 2025. PMID: 39811647.
10. Gan Q, Ding Y, Wu Y, Zhang Y, Meng QH, Ding QQ, Lu H, Shelburne SA, Ehlers RA 2nd, Han XY. Infections Due to Corynebacterium kroppenstedtii With Focus on Granulomatous Lobular Mastitis for Tissue Specificity, Pathogenesis, Bacteriologic Workup, and Treatment. Arch Pathol Lab Med 149(9):812-821, 2025. e-Pub 2025. PMID: 39800878.
11. Mir, M, Soto, F, Gomez, PA, Arroyo, RR, Suresh, A, Su, A, Gan, Q, Stewart, J, Adachi, R, Balachandran, D, Bashoura, L, Casal, RF, Dickey, BF, Eapen, GA, Evans, S, Grosu, HB, Jimenez, C, Lin, J, Ost, D, Sabath, BF, Shannon, VR, Naing, A, Gao, J, Wu, J, Suresh, K, Faiz, S, Altan, M, Sheshadri, A. Bronchoalveolar lavage cell percentages as diagnostic markers of immune checkpoint inhibitor pneumonitis. Frontiers in Medicine 12, 2025. e-Pub 2025. PMID: 40529125.
12. Sakshi FNU, Mallikarjuna VS, Stewart JM, Gan Q. Extramedullary Hematopoiesis in Serous Cavity Fluids: A Closer Look at This Rare Phenomenon With Diagnostic Pitfalls and Prognostic Significance. Diagn Cytopathol 53(4):167-172, 2024. e-Pub 2024. PMID: 39704045.
13. Davaro E, Rohra P, Kundu U, Gan Q. Bilateral Cystic Endosalpingiosis in Cervical Lymph Nodes Mimicking Metastatic Papillary Thyroid Carcinoma Morphologically on Cytology: A Case Report and Literature Review of Diagnostic Challenges. Diagn Cytopathol, 2024. e-Pub 2024. PMID: 39679640.
14. Sewastjanow-Silva M, Kwiatkowski E, Yamashita K, Abdelhakeem A, Yoshimura K, Vicentini ER, Pizzi MP, Jin J, Fan Y, Zou G, Wang L, Yin F, Dhar SS, Blum Murphy M, Mares JE, Li JJ, Gan Q, Waters RE, Rogers JE, Ajani JA. Three biomarkers (HER2, PD-L1, and microsatellite status) in a large cohort of metastatic gastroesophageal adenocarcinomas: The MD Anderson Cancer Center experience. Int J Cancer 155(12):2277-2286, 2024. e-Pub 2024. PMID: 38995150.
15. Donthi D, Donthi D, Gan Q, Gan Q, Ding QQ, Ding QQ, Krishnamurthy S, Krishnamurthy S. Trichorhinophalangeal syndrome 1 expression in breast and nonbreast metastases from Mullerian, lung, gastrointestinal tract, and pancreatic primary tumors by immunohistochemistry with cytology cell block specimens. Cancer Cytopathol 132(12):799-808, 2024. e-Pub 2024. PMID: 39264831.
16. Hara, Y, Baba, Y, Oda, E, Harada, K, Yamashita, K, Toihata, T, Kosumi, K, Iwatsuki, M, Miyamoto, Y, Tsutsuki, H, Gan, Q, Waters, R, Komohara, Y, Sawa, T, Ajani, JA, Baba, H. Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers. British journal of cancer 131(5):797-807, 2024. e-Pub 2024. PMID: 38992099.
17. Yamashita K, Sewastjanow-Silva M, Yoshimura K, Rogers JE, Rosa Vicentini E, Pool Pizzi M, Fan Y, Zou G, Li JJ, Blum Murphy M, Gan Q, Waters RE, Wang L, Ajani JA. SMARCA4 Mutations in Gastroesophageal Adenocarcinoma: An Observational Study via a Next-Generation Sequencing Panel. Cancers (Basel) 16(7), 2024. e-Pub 2024. PMID: 38610978.
18. Gong B, Li D, Zhang Y, Kusko R, Lababidi S, Cao Z, Chen M, Chen N, Chen Q, Chen Q, Dai J, Gan Q, Gao Y, Guo M, Hariani G, He Y, Hou W, Jiang H, Kushwaha G, Li JL, Li J, Li Y, Liu LC, Liu R, Liu S, Meriaux E, Mo M, Moore M, Moss TJ, Niu Q, Patel A, Ren L, Saremi NF, Shang E, Shang J, Song P, Sun S, Urban BJ, Wang D, Wang S, Wen Z, Xiong X, Yang J, Yin L, Zhang C, Zhang R, Bhandari A, Cai W, Eterovic AK, Megherbi DB, Shi T, Suo C, Yu Y, Zheng Y, Novoradovskaya N, Sears RL, Shi L, Jones W, Tong W, Xu J. Extend the benchmarking indel set by manual review using the individual cell line sequencing data from the Sequencing Quality Control 2 (SEQC2) project. Sci Rep 14(1):7028, 2024. e-Pub 2024. PMID: 38528062.
19. Laberiano-Fernandez C, Gan Q, Wang SM, Tamegnon A, Wistuba I, Yoon E, Roy-Chowdhuri S, Parra ER. Exploratory pilot study to characterize the immune landscapes of malignant pleural effusions and their corresponding primary tumors from patients with breast carcinoma and lung adenocarcinoma. J Am Soc Cytopathol 13(3):161-173, 2024. e-Pub 2024. PMID: 38519275.
20. Fakhri NL, Gan Q. Desmoplastic Small Round Cell Tumor Involving Serous Fluid: Cytologic Features and Diagnostic Pitfalls A Series of 8 Cases. Am J Clin Pathol 160(4):417-424, 2023. e-Pub 2023. PMID: 37289439.
21. Rodriguez JJ, Gan Q, Kundu U. A cytopathological tale of a pediatric renal tumor. Diagn Cytopathol 51(9):584-586, 2023. e-Pub 2023. PMID: 37338161.
22. Lizarraga Madrigal D, Cabrera Charleston M, Khan A, Eapen G, Kalhor N, Gan Q, Grosu H. Pulmonary Sclerosing Pneumocytomas Mimicking Lung Cancer. Cureus 15(4):e37395, 2023. e-Pub 2023. PMID: 37182004.
23. Najjar S, Gan Q, Stewart J, Sneige N. The utility of claudin-4 versus MOC-31 and Ber-EP4 in the diagnosis of metastatic carcinoma in cytology specimens. Cancer Cytopathol 131(4):245-253, 2023. e-Pub 2023. PMID: 36522809.
24. Rohra P, Ding C, Yoon EC, Gan Q. A pilot study: Comparison of TRPS1 and GATA3 immunoperoxidase staining using cytologic smears in entities reportedly positive for GATA3. Cancer Cytopathol 130(12):930-938, 2022. e-Pub 2022. PMID: 35790088.
25. Gan Q, Caraway NP, Ding C, Stewart JM. Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration. Am J Clin Pathol 158(2):242-248, 2022. e-Pub 2022. PMID: 35311939.
26. Yoon EC, Wang G, Parkinson B, Huo L, Peng Y, Wang J, Salisbury T, Wu Y, Chen H, Albarracin CT, Resetkova E, Middleton LP, Krishnamurthy S, Gan Q, Sun H, Huang X, Shen T, Chen W, Parwani AV, Sahin AA, Li Z, Ding Q. TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma. Hum Pathol 125:97-107, 2022. e-Pub 2022. PMID: 35413381.
27. Gan Q, Roy-Chowdhuri S, Duose DY, Stewart JM, Coronel E, Bhutani MS, Lee JH, Weston B, Ge PS, Ross WA, Maitra A. Adequacy evaluation and use of pancreatic adenocarcinoma specimens for next-generation sequencing acquired by endoscopic ultrasound-guided FNA and FNB. Cancer Cytopathol 130(4):275-283, 2022. e-Pub 2022. PMID: 34905283.
28. Wang J, Wang WL, Sun H, Huo L, Wu Y, Chen H, Gan Q, Meis JM, Maloney N, Lazar AJ, Yoon EC, Albarracin CT, Krishnamurthy S, Middleton LP, Resetkova E, Yu W, Tan D, Lu W, Solis Soto LM, Wang S, Wistuba II, Parwani AV, Prieto VG, Sahin AA, Li Z, Ding Q. Expression of TRPS1 in phyllodes tumor and sarcoma of the breast. Hum Pathol 121:73-80, 2022. e-Pub 2022. PMID: 35063444.
29. Hou T, Liu Z, Gan Q, Debnam JM, Krishnamurthy S. Clinical and cytopathological features of suspected thyroglossal duct cysts and neoplasms arising from them: A large series from a referral cancer center. Cancer Cytopathol 130(1):72-79, 2022. e-Pub 2022. PMID: 34529338.
30. Hao D, He S, Harada K, Pizzi MP, Lu Y, Guan P, Chen L, Wang R, Zhang S, Sewastjanow-Silva M, Abdelhakeem A, Shanbhag N, Bhutani M, Han G, Lee JH, Zhao S, Weston B, Blum Murphy M, Waters R, Estrella JS, Roy-Chowdhuri S, Gan Q, Lee JS, Peng G, Hanash SM, Calin GA, Song X, Zhang J, Song S, Wang L, Ajani JA. Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma. Gut 70(11):2055-2065, 2021. e-Pub 2021. PMID: 33334899.
31. Song S, Xu Y, Huo L, Zhao S, Wang R, Li Y, Scott AW, Pizzi MP, Wang Y, Fan Y, Harada K, Jin J, Ma L, Yao X, Shanbhag ND, Gan Q, Roy-Chowdhuri S, Badgwell BD, Wang Z, Wang L, Ajani JA. Patient-derived cell lines and orthotopic mouse model of peritoneal carcinomatosis recapitulate molecular and phenotypic features of human gastric adenocarcinoma. J Exp Clin Cancer Res 40(1):207, 2021. e-Pub 2021. PMID: 34162421.
32. Ai D, Yao J, Yang F, Huo L, Chen H, Lu W, Soto LMS, Jiang M, Raso MG, Wang S, Bell D, Liu J, Wang H, Tan D, Torres-Cabala C, Gan Q, Wu Y, Albarracin C, Hung MC, Meric-Bernstam F, Wistuba II, Prieto VG, Sahin AA, Ding Q. TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer. Mod Pathol 34(4):710-719, 2021. e-Pub 2021. PMID: 33011748.
33. Chin KE, Kwon D, Gan Q, Ramalingam PX, Wistuba II, Prieto VG, Aung PP. Transition From a Standard to a Hybrid On-Site and Remote Anatomic Pathology Training Model During the Coronavirus Disease 2019 (COVID-19) Pandemic. Arch Pathol Lab Med 145(1):22-31, 2021. e-Pub 2021. PMID: 32937659.
34. Porteus C, Gan Q, Gong Y, Pantanowitz L, Henderson-Jackson E, Saeed-Vafa D, Mela N, Peterson D, Ahmad N, Ahmed A, Bui M. Sclerosing epithelioid fibrosarcoma: cytologic characterization with histologic, immunohistologic, molecular, and clinical correlation of 8 cases. J Am Soc Cytopathol 9(6):513-519, 2020. e-Pub 2020. PMID: 32624384.
35. Hou T, Stewart JM, Lee JH, Gan Q. Solid Tumor Metastases to the Pancreas Diagnosed Using Fine-Needle Aspiration. Am J Clin Pathol 154(5):692-699, 2020. e-Pub 2020. PMID: 32651950.
36. Hou T, Gan Q, Joseph CT, Sun X, Gong Y. Insulinoma-associated protein 1 immunostaining for various types of neuroendocrine tumors on FNA smears. Cancer Cytopathol 128(10):725-732, 2020. e-Pub 2020. PMID: 32573984.
37. Gan Q, Edeiken BS, Chen MM, Grubbs EG, Busaidy NL, Zafereo M, Perrier ND, Gule-Monroe MD, Krishnamurthy S. Utility of subcategorization of atypia of undetermined significance/follicular lesion of undetermined significance category in ultrasound-guided thyroid fine-needle aspiration in a large referral cancer center. J Am Soc Cytopathol 8(6):309-316, 2019. e-Pub 2019. PMID: 31526696.
38. Gan Q, Stewart JM, Valik E, Eapen G, Caraway NP. Cytologic Evaluation of Positron Emission Tomography-Computed Tomography-Positive Lymph Nodes Sampled by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Experience at a Large Cancer Center. Arch Pathol Lab Med 143(10):1265-1270, 2019. e-Pub 2019. PMID: 31063012.
39. Gan Q, Joseph CT, Guo M, Zhang M, Sun X, Gong Y. Utility of NKX3.1 Immunostaining in the Detection of Metastatic Prostatic Carcinoma on Fine-Needle Aspiration Smears. Am J Clin Pathol 152(4):495-501, 2019. e-Pub 2019. PMID: 31175351.
40. Gan Q, Crumley S, Broaddus RR. Molecular Modifiers of Hormone Receptor Action: Decreased Androgen Receptor Expression in Mismatch Repair Deficient Endometrial Endometrioid Adenocarcinoma. Int J Gynecol Pathol 38(1):44-51, 2019. e-Pub 2019. PMID: 29210800.
41. Eppelheimer CN, Marti JL, Eisenberg A, Gan Q, Shabalova R, Cohen JM, Fulop T. A Case of Secondary Angiosarcoma of the Breast after Breast-conserving Surgery and Radiation: Review of Radiologic and Pathologic Findings. J Clin Imaging Sci 5:45, 2015. e-Pub 2015. PMID: 26430538.
42. Buono KD, Vadlamuri D, Gan Q, Levison SW. Leukemia inhibitory factor is essential for subventricular zone neural stem cell and progenitor homeostasis as revealed by a novel flow cytometric analysis. Dev Neurosci 34(5):449-62, 2012. e-Pub 2012. PMID: 23258129.
43. Gan Q, Thiébaud P, Thézé N, Jin L, Xu G, Grant P, Owens GK. WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2. J Biol Chem 286(24):21853-64, 2011. e-Pub 2011. PMID: 21531708.
44. Jin L, Gan Q, Zieba BJ, Goicoechea SM, Owens GK, Otey CA, Somlyo AV. The actin associated protein palladin is important for the early smooth muscle cell differentiation. PLoS One 5(9):e12823, 2010. e-Pub 2010. PMID: 20877641.
45. Yoshida T, Gan Q, Franke AS, Ho R, Zhang J, Chen YE, Hayashi M, Majesky MW, Somlyo AV, Owens GK. Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation. J Biol Chem 285(27):21175-84, 2010. e-Pub 2010. PMID: 20439457.
46. Deaton RA, Gan Q, Owens GK. Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle. Am J Physiol Heart Circ Physiol 296(4):H1027-37, 2009. e-Pub 2009. PMID: 19168719.
47. Cherepanova OA, Pidkovka NA, Sarmento OF, Yoshida T, Gan Q, Adiguzel E, Bendeck MP, Berliner J, Leitinger N, Owens GK. Oxidized phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration. Circ Res 104(5):609-18, 2009. e-Pub 2009. PMID: 19168440.
48. Yoshida T, Gan Q, Owens GK. Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids. Am J Physiol Cell Physiol 295(5):C1175-82, 2008. e-Pub 2008. PMID: 18768922.
49. Gan Q, Yoshida T, Li J, Owens GK. Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression. Circ Res 101(9):883-92, 2007. e-Pub 2007. PMID: 17823374.
50. Yoshida T, Gan Q, Shang Y, Owens GK. Platelet-derived growth factor-BB represses smooth muscle cell marker genes via changes in binding of MKL factors and histone deacetylases to their promoters. Am J Physiol Cell Physiol 292(2):C886-95, 2007. e-Pub 2007. PMID: 16987998.

Invited Articles

1. Yu WD, Gan Q, Gong Y. The Yokohama System for Reporting Breast Cytopathology. Journal of Clinical and Translational Pathology, 2023. e-Pub 2023.
2. Gan Q, Roy-Chowdhuri S. Specimen Considerations in Molecular Oncology Testing. Clin Lab Med 42(3):367-383, 2022. e-Pub 2022. PMID: 36150817.
3. Chasen NN, Wang JR, Gan Q, Ahmed S. Imaging of Cervical Lymph Nodes in Thyroid Cancer: Ultrasound and Computed Tomography. Neuroimaging Clin N Am 31(3):313-326, 2021. e-Pub 2021. PMID: 34243866.

Review Articles

1. Li, JJ, Rogers, JE, Waters, R, Gan, Q, Blum Murphy, M, Ajani, JA. Evolution of Therapeutics for Locally Advanced Upper Gastrointestinal Adenocarcinoma. Cancers 17(8), 2025. e-Pub 2025. PMID: 40282483.
2. Rogers JE, Gan Q, Waters RE, Horak AA, Ajani JA. Targeted and combination immunotherapies using biologics for gastric cancer: the state-of-the-art. Expert Opin Biol Ther 24(10):1005-1015, 2024. e-Pub 2024. PMID: 39315517.
3. Kundu U, Gan Q, Donthi D, Sneige N. The Utility of Fine Needle Aspiration (FNA) Biopsy in the Diagnosis of Mediastinal Lesions. Diagnostics (Basel) 13(14), 2023. e-Pub 2023. PMID: 37510144.
4. Yu, W, Gan, Q, Gong, Y. The Yokohama System for Reporting Breast Cytopathology. Journal of Clinical and Translational Pathology 3(2):99-105, 2023. e-Pub 2023.
5. Yu, W, Gan, Q, Gong, Y. The Yokohama System for Reporting Breast Cytopathology. Journal of Clinical and Translational Pathology 3(2):99-105, 2023. e-Pub 2023.
6. Velez-Perez A, Abuharb B, Bammert CE, Landon G, Gan Q. Detection of non-haematolymphoid malignancies in bronchoalveolar lavages-A cancer centre's 10 year experience. Cytopathology 33(4):449-453, 2022. e-Pub 2022. PMID: 35077018.
7. Gan Q, Roy-Chowdhuri S. Small but powerful: the promising role of small specimens for biomarker testing. J Am Soc Cytopathol 9(5):450-460, 2020. e-Pub 2020. PMID: 32507626.
8. Gan Q, Yoshida T, McDonald OG, Owens GK. Concise review: epigenetic mechanisms contribute to pluripotency and cell lineage determination of embryonic stem cells. Stem Cells 25(1):2-9, 2007. e-Pub 2007. PMID: 17023513.

Other Articles

1. Mir, M, Soto, F, Gomez, PA, Arroyo, RR, Suresh, A, Su, A, Gan, Q, Stewart, J, Adachi, R, Balachandran, D, Bashoura, L, Casal, RF, Dickey, BF, Eapen, GA, Evans, S, Grosu, HB, Jimenez, C, Lin, J, Ost, D, Sabath, BF, Shannon, VR, Naing, A, Gao, J, Wu, J, Suresh, K, Faiz, S, Altan, M, Sheshadri, A Correction. Frontiers in Medicine 12, 2025. PMID: 40641984.

Abstracts

1. Gan Q. Utility of Whole Slide Imaging for Evaluation of Thyroid Fine Needle Aspiration: A Multi-reader Prospective Study. USCAP 113th Annual Meeting.
2. Gan Q. Angiosarcoma in Fluids: A Review of Cytologic Features in 22 Patients. USCAP 113th Annual Meeting.

Book Chapters

1. Gan Q, Yang J, Heymann JJ, Roy-Chowdhuri S. Diagnostic category: Atypical. In: WHO Reporting System for Pancreaticobiliary Cytopathology. 1st. International Agency for Research on Cancer (IARC), 2023.

Letters to the Editor

1. Wang, WJ, Jeffrey Medeiros, L, Tang, G, Garces, S, Guo, CC, Gan, Q, Li, S, Lin, P, Wang, W, Xu, J. CD30+ High Grade Neoplasm With Expression of β-HCG and T-Cell Markers. Pathol Int 76: e70120, 2026.