Rebecca E Waters, D.O.
Department of Anatomical Pathology, Division of Pathology-Lab Medicine Div
About Dr. Rebecca E Waters
As a gastrointestinal pathologist, I have a broad background in anatomic pathology with specific training and expertise in gastrointestinal, hepatic and pancreaticobiliary pathology. In addition to my clinical duties, I am involved in multiple research projects with our colleagues in gastrointestinal oncology. Most recently, my investigative and collaborative efforts have focused on potential biomarkers for early diagnosis, treatment effectiveness, and tumor progression in gastric and gastroesophageal cancers.
Present Title & Affiliation
Primary Appointment
Associate Professor, Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2013 | University of North Texas Health Science Center - Texas College of Osteopathic Medicine, Fort Worth, Texas, US, Osteopathic Medicine, Doctor of Osteopathic Medicine |
| 2007 | Texas A&M University, College Station, Texas, US, Nutrition, BS |
Postgraduate Training
| 2024-2024 | Leadership, MD Anderson Quality College: Six Sigma Yellow Belt Certification, MD Anderson Cancer Center, Houston, Texas |
| 2024-2024 | Leadership, MD Anderson Quality College: Essentials of Quality Improvement, MD Anderson Cancer Center, Houston, Texas |
| 2021-2021 | Leadership, Stanford WellMD Center's Physician Well-Being Director Course, Stanford University School of Medicine WellMD & WellPhD Center, Palo Alto, California |
| 2018-2018 | Leadership, Engaged Leadership Academy, College of American Pathologists, Chicago, Illinois |
| 2018-2019 | Clinical Fellowship, Gastrointestinal, Hepatic and Pancreaticobiliary Pathology, Cleveland Clinic, Cleveland, Ohio |
| 2017-2018 | Clinical Fellowship, Surgical Pathology, Mayo Clinic, Rochester, Minnesota |
| 2013-2017 | Clinical Residency, Anatomic/Clinical Pathology, University of Texas Medical Branch, Galveston, Texas |
Licenses & Certifications
| 2017 | Anatomic Pathology, American Board of Pathology |
| 2017 | Texas Medical Board |
| 2016 | Minnesota Board of Medical Practice |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2025
Administrative Appointments/Responsibilities
Division Wellness Lead, Division of Pathology and Laboratory Medicine, MD Anderson Cancer Center Division Wellness Leads Council, Houston, TX, 2020 - Present
Other Professional Positions
Advisor, Gastric/Gastroesophageal Junction Cancer Committee, Astellas, Houston, TX, 2021 - 2023
Delegate for state of Texas, College of American Pathologists House of Delegates, Houston, TX, 2020 - Present
Committee member, College of American Pathologists Digital Pathology Committee, Chicago, IL, 2015 - 2017
Intramural Institutional Committee Activities
Member, MD Anderson Faculty Wellness Collaborative, MD Anderson Cancer Center, 2026 - Present
Chair, MD Anderson GI Pathology Fellowship Program Evaluation Committee, MD Anderson Cancer Center, 2024 - Present
Chair, MD Anderson Division of Pathology and Laboratory Medicine Wellness Working Group Committee, MD Anderson Cancer Center, 2023 - Present
Member, MD Anderson Professional Wellness Academic Consortium (PWAC) Survey Sub-committee, MD Anderson Cancer Center, 2021 - 2023
Representative, Department of Pathology, MD Anderson Junior Faculty Committee, MD Anderson Cancer Center, 2020 - 2026
Division Wellness Lead, Division of Pathology and Laboratory Medicine, MD Anderson Faculty Wellness Program, MD Anderson Cancer Center, 2020 - Present
Member, MD Anderson GI Pathology Fellowship Program Evaluation Committee, MD Anderson Cancer Center, 2019 - Present
Member, MD Anderson GI Pathology Fellowship Clinical Competency Committee, MD Anderson Cancer Center, 2019 - Present
Honors & Awards
| 2026 - Present | 2026 Nominee: MD Anderson Faculty Wellness Collaborative (FWC), MD Anderson Cancer Center |
| 2026 - Present | 2026 Nominee: Stress First Aid (SFA), MD Anderson Cancer Center |
| 2024 | Nominee: MD Anderson Faculty Academic Career Development Academy, MD Anderson Cancer Center |
| 2023 | Recognized for pathology career with article : A “Whole Person Approach” to Histology, Today's Clinical Lab |
| 2023 | Excellence in Safety Award: Safety Hero of the Month, MD Anderson Cancer Center |
| 2021 | Excellence in Safety Award: Safety Hero of the Month, MD Anderson Cancer Center |
| 2021 | Stanford WellMD Center Physician Wellness Director Course, Stanford University |
| 2020 | Departmental Representative, MDACC Junior Faculty Committee, Representative for Department, MD Anderson Cancer Center |
| 2018 | Nominee: Engaged Leadership Academy, College of American Pathologists |
| 2016 | Excellence in Research Award, University of Texas Medical Branch -Galveston Department of Pathology |
| 2016 | The Edward S. Reynolds Award in Research, University of Texas Medical Branch -Galveston Department of Pathology |
| 2015 | The Edward S. Reynolds Award in Research, University of Texas Medical Branch Department of Pathology |
| 2013 | Medical Student Research Award, University of North Texas Health Science Center Research Appreciation Day |
| 2012 | Complementary & Alternative Medicine Research Grant with National Institute of Health, University of North Texas Health Science Center |
| 2010 | Sigma Sigma Phi Honorary Osteopathic Service Society Inductee, University of North Texas Health Science Center |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2025. Discussion of Case 5: Amphicrine Carcinoma and its Mimics. Invited. William O. Russell Annual Conference: Nuts and Bolts in Surgical Pathology. Houston, Texas, US.
- 2025. Molecular Pathology of Gastric and Gastroesophageal Junctional Cancer. Invited. Astrazeneca Scientific Workshop: Management of Resectable and Advanced Gastric/GEJ Adenocarcinomas. Houston, Texas, US.
- 2025. Clinical decision-making for gastric/GEJ cancer: Present and Future. Panelist. Astrazeneca Scientific Workshop: Management of Resectable and Advanced Gastric/GEJ Adenocarcinomas. Houston, Texas, US.
- 2024. Addressing Physician Burnout: A Focus on the Field of Pathology and Laboratory Medicine. Conference. Grand Rounds, Division of Pathology and Laboratory Medicine Grand Rounds. Houston, TX, US.
- 2022. Role of Pathology in Work-Up of Colorectal Cancer. Conference. Bayer & MD Anderson Education Seminar. Houston, TX, US.
- 2014. Thyroid Follicular Adenoma with Insular and Trabecular Patterns: A Case Report. Poster. Texas Society of Pathologists 2014 Annual Meeting. Houston, TX, US.
Regional Presentations
- 2023. Pathology Career Panel Discussion. Invited. University of Texas Medical Branch Careers in Pathology Conference. Galveston, TX, US.
- 2016. Investigating predictive models based on circulating cell-free INK4A DNA methylation alpha-fetoprotein, platelet count, and age for diagnosis and prognosis of hepatocellular carcinoma (poster presentation). Poster. Texas Society of Pathologists 2016 Annual Meeting. Dallas, TX, US.
- 2015. Digital Pathology - Current Experiences and Future Prospectives. Conference. Department of Pathology Grand Rounds. Galveston, TX, US.
- 2015. Anatomic distribution of smoking related interstitial fibrosis (SRIF) in lung lobectomy/pneumonectomy specimens (poster presentation). Poster. Texas Society of Pathologists 2015 Annual Meeting. San Antonio, TX, US.
- 2013. Soy Phytoestrogens Enhance Neurogenesis in the Rat Sub-Ventricular Zone (poster presentation). Poster. Research Appreciation Day. Ft. Worth, TX, US.
National Presentations
- 2026. Neighborhood analyses in nerve fiber-associated tumor regions in hereditary diffuse gastric cancer [abstract]. Poster. American Association for Cancer Research Annual Meeting 2026. Philadelphia, Pennsylvania, US.
- 2026. Spatially organized transcriptional programs and tumor-stroma interfaces shape immunotherapy response in microsatellite instability-high gastrointestinal cancers. Poster. American Association for Cancer Research Annual Meeting 2026. Philadelphia, Pennsylvania, US.
- 2025. Transcriptomic Programs Associated to Different Histological Stages in the Pathogenesis of Hereditary Diffuse Gastric Cancer. Conference. USCAP. Boston, MA, US.
- 2025. Rectal Cancer: A Pathologist’s Perspective for Radiology. Invited. Society of Abdominal Radiology Annual 2025 meeting. Tucson, AZ, US.
- 2023. Greatest GI Pathology Cases of 2023. Invited. Virtual presentation, US.
- 2023. Accurate Assessment for Colorectal Cancer Diagnosis and Staging: Challenging and Emerging Concepts (Podium presentation). Conference. American Society of Clinical Pathology 2023 Annual Meeting. Long beach, CA, US.
- 2023. Finding Your Career Fit. Invited. College of American Pathologists Webinar- New In Practice Pathologists. Chicago, IL, US.
- 2022. Unifocal Peritoneal Malignant Mesothelioma as Initial Presentation of Lynch Syndrome: A Case Report and Brief Review (poster presentation). Poster. American Society of Clinical Pathology (ASCP) 2022 Annual Meeting. Chicago, IL, US.
- 2019. Post-neoadjuvant pancreatic ductal adenocarcinoma tumor burden, not tumor size, may predict outcome (poster presentation). Poster. United State and Canadian Academy of Pathology 2019 Annual Meeting. National Harbor, MD, US.
- 2016. Investigating predictive models based on circulating cell-free INK4A DNA methylation alpha-fetoprotein, platelet count, and age for diagnosis and prognosis of hepatocellular carcinoma (poster presentation). Poster. United State and Canadian Academy of Pathology 2016 Annual Meeting. Seattle, WA, US.
- 2015. Anatomic distribution of smoking related interstitial fibrosis (SRIF) in lung lobectomy/pneumonectomy specimens (poster presentation). Poster. United State and Canadian Academy of Pathology 2015 Annual Meeting. Boston, MD, US.
- 2014. Human Papillomavirus presence in extragenital squamous cell carcinoma in situ of the skin (poster presentation). Poster. American Society of Dermatopathology 2014 Annual Meeting. Chicago, IL, US.
International Presentations
- 2026. Enhancing Multidisciplinary Care in Rectal Cancer Care. Panelist. MD Anderson- Madrid Colorectal Program Collaboration. Madrid, ES.
- 2025. Challenging and Emerging Concepts in Colorectal Cancer Assessment. Invited. XXXII Congreso Nacional de la SEAP-IAP (32nd National Congress of the Spanish Society of Pathological Anatomy). San Sebastian, ES.
- 2025. New and Upcoming Biomarkers in Adenocarcinoma of the GI Tract. Invited. XXXII Congreso Nacional de la SEAP-IAP (32nd National Congress of the Spanish Society of Pathological Anatomy). San Sebastian, ES.
- 2018. Atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma in patients <40 years: a study of 103 patients (poster presentation). Poster. United State and Canadian Academy of Pathology 2018 Annual Meeting. Vancouver, CA.
Formal Peers
- 2024. Grand Rounds: Addressing Physician Burnout: A Focus on the Field of Pathology and Laboratory Medicine. Houston, Texas, US.
- 2023. Greatest GI Pathology Cases of 2023. Invited, US.
- 2023. University of Texas Medical Branch Career Panel Discussion for Pathology Residents and Fellows (panelist). Invited. Galveston, TX, US.
- 2023. Finding Your Career Fit, webinar (panelist). Invited. Chicago, IL, US.
- 2016. Investigating predictive models based on circulating cell-free INK4A DNA methylation alpha-fetoprotein, platelet count, and age for diagnosis and prognosis of hepatocellular carcinoma. Invited. Houston, TX, US.
Grant & Contract Support
| Date: | 2022 - Present |
| Title: | GPCR-kinase 3 (GRK3) as novel therapeutic target in advanced gastric adenocarcinoma |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | R01CA272906 |
| Date: | 2020 - 2023 |
| Title: | A Retrospective Study of Prevalence and Prognostic Association of Claudin 18.2 (CLDN18.2) Expression in Gastric and Gastroesophageal junction adenocarcinoma patients; Astellas |
| Funding Source: | Astellas |
| Role: | Collaborator |
| ID: | 2019-1254 |
Selected Publications
Peer-Reviewed Articles
- Zou G, Yoshimura K, Fan Y, Zeng L, Bhati AS, Vanpariya BR, Dai E, Yamashita K, Wang L, Wu J, Shao S, Scott AW, Jin J, Pizzi MP, Yao X, Brown CA, Cao F, Wang R, Han X, Li J, Chen H, Wang P, Wang L, Liu B, Zhou J, Lo YH, Gan Q, Waters R, Yin F, Song S, Ajani JA, Dhar SS. Pharmacologic Inhibition of SOX9-CDK4 by CYD-4-61 Impairs Gastric Adenocarcinoma Growth and Amplifies Anti-PD-1 Response. Cancer Lett, 2026. e-Pub 2026. PMID: 42567470.
- Blum Murphy MA, Xiao L, Sewastjanow-Silva M, Wang X, Badgwell BD, Mansfield PF, Ikoma N, Pabon CM, Lee JH, Bhutani MS, Weston B, Coronel E, Smith GL, Holliday EB, Tian J, Barabrah AM, Das P, Minsky BD, Waters RE, Estrella JS, Li JJ, Ajani JA. Perioperative Nivolumab and Ipilimumab with Chemotherapy and Chemoradiation for Resectable Gastric and Gastroesophageal Junction Adenocarcinoma: A Phase 1/2 Non-Randomized Clinical Trial. Cancers 18(14):2198, 2026. e-Pub 2026. PMID: 42512265.
- Yamashita K, Kwiatkowski E, Sewastjanow-Silva M, Rogers JE, Yoshimura K, Pizzi MP, Gan Q, Li JJ, Waters RE, Murphy MB, Iwatsuki M, Hofstetter WL, Chen A, Yuan Y, Ajani JA. Clinical Machine Learning Model for Predicting Pathological Complete Response in Patients with Esophageal and Gastroesophageal Junction Adenocarcinoma After Trimodality Therapy. Ann Surg Oncol 33(8):7133-7141, 2026. e-Pub 2026. PMID: 42002713.
- Sewastjanow-Silva M, Oh M, Chang L, Ganguli A, Rogers JE, Waters RE, Vicentini ER, Yamashita K, Totev TI, Wu EQ, Yang H, Iwata K, Ajani JA. Symptom Burden and Healthcare Resource Use in Patients With Claudin 18.2–Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma: A Retrospective Review. Clinical Medicine Insights: Oncology 20:1-13, 2026. e-Pub 2026. PMID: 41919275.
- Shui L, Liu Y, Lubo Julio IC, Clemenceau JR, Hoi XP, Dai Y, Lu W, Min J, Khan K, Roemer B, Jiang M, Waters RE, Colbert K, Maitra A, Wintermark M, Yuan Y, Chan KS, Hwang TH, Mansfield PF, Davis J, Solis Soto LM, Wang L, Li L, Li Z. UniST: A Unified Computational Framework for 3D Spatial Transcriptomics Reconstruction. bioRxiv, 2026. e-Pub 2026. PMID: 41889901.
- Fan Y, Vykoukal JV, Song S, Pizzi MP, Zou G, Yoshimura K, Jin J, Katayama H, Calin GA, Waters RE, Gan Q, Wang L, Hanash S, Dhar SS, Ajani JA. Protocol for isolating patient-derived ascites cells and extracellular vesicles from gastric cancer peritoneal metastases. STAR Protoc 6(4):104133, 2025. e-Pub 2025. PMID: 41105517.
- Xian, W, Wang, S, Xie, J, Yamamoto, Y, Khorrami, M, Zhang, Y, Montes, RC, Desales, C, Khorrami, M, Mory, Z, Hoffman, A, Su, A, Nguyen, C, Davies, P, Stephan, C, Pan, S, Wu, W, Liu, Y, Siegelman, J, Waters, R, Ross, WA, Song, S, Metersky, ML, Beer, DG, Crum, CP, Stewart, AJ, Vincent, M, Russell, R, Izard, RA, Ho, KY, Hung-Sen Lai, J, Bachovchin, WW, Ajani, JA, McKeon, FD. Evolution of Esophageal Adenocarcinoma From Precursor Lesion Stem Cells. Gastroenterology 169(2):277-293.e4, 2025. e-Pub 2025. PMID: 40090599.
- Song, S, Fan, Y, Zou, G, Huo, L, Kumar, J, Li, Y, Wang, R, Dai, E, Jin, J, Scott, AW, Shao, SH, Pizzi, M, Vykoukal, JV, Katayama, H, Hanash, S, Calin, GA, Zhang, X, Lee, MG, Wang, Z, Lo, Y, Gan, Q, Waters, R, Yin, F, Wang, L, Cheng, X, Ajani, JA, Dhar, SS. KAP1 promotes gastric adenocarcinoma progression by activating Hippo/YAP1 signaling via binding to HNRNPAB. Cancer Letters 621, 2025. e-Pub 2025. PMID: 40189014.
- Yoshimura, K, Zou, G, Fan, Y, Yamashita, K, Wang, L, Wu, J, Wang, R, Shao, SH, Scott, AW, Jin, J, Pizzi, M, Yao, X, Brown, CA, Wang, L, Gan, Q, Waters, R, Yin, F, Song, S, Dhar, SS, Ajani, JA. HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer. Cancer Letters 610, 2025. e-Pub 2025. PMID: 39603381.
- Fan, Y, Song, S, Pizzi, M, Zou, G, Vykoukal, JV, Yoshimura, K, Jin, J, Calin, GA, Waters, R, Gan, Q, Wang, L, Hanash, S, Dhar, SS, Ajani, JA. Exosomal Galectin-3 promotes peritoneal metastases in gastric adenocarcinoma via microenvironment alterations. iScience 28(1), 2025. e-Pub 2025. PMID: 39811647.
- Sewastjanow-Silva M, Kwiatkowski E, Yamashita K, Abdelhakeem A, Yoshimura K, Vicentini ER, Pizzi MP, Jin J, Fan Y, Zou G, Wang L, Yin F, Dhar SS, Blum Murphy M, Mares JE, Li JJ, Gan Q, Waters RE, Rogers JE, Ajani JA. Three biomarkers (HER2, PD-L1, and microsatellite status) in a large cohort of metastatic gastroesophageal adenocarcinomas: The MD Anderson Cancer Center experience. Int J Cancer 155(12):2277-2286, 2024. e-Pub 2024. PMID: 38995150.
- Hara, Y, Baba, Y, Oda, E, Harada, K, Yamashita, K, Toihata, T, Kosumi, K, Iwatsuki, M, Miyamoto, Y, Tsutsuki, H, Gan, Q, Waters, R, Komohara, Y, Sawa, T, Ajani, JA, Baba, H. Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers. British journal of cancer 131(5):797-807, 2024. e-Pub 2024. PMID: 38992099.
- Cheng X, Dai E, Wu J, Flores NM, Chu Y, Wang R, Dang M, Xu Z, Han G, Liu Y, Chatterjee D, Hu C, Ying J, Du Y, Yang L, Guan X, Mo S, Cao X, Pei G, Jiang J, Lu X, Benitez AM, Waters RE, Pizzi MP, Shanbhag N, Fan Y, Peng F, Hanash SM, Calin G, Futreal A, Song S, Yee C, Mazur PK, Qin JJ, Ajani JA, Wang L. Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response. Gastroenterology 167(7):1345-1357, 2024. e-Pub 2024. PMID: 39097198.
- Waters R, Sewastjanow-Silva M, Yamashita K, Abdelhakeem A, Iwata KK, Moran D, Elsouda D, Guerrero A, Pizzi M, Vicentini ER, Shanbhag N, Ta A, Chatterjee D, Ajani JA. Retrospective Study of Claudin 18 Isoform 2 Prevalence and Prognostic Association in Gastric and Gastroesophageal Junction Adenocarcinoma. JCO Precision Oncology 8:p.e2300543-e2300543, 2024. e-Pub 2024. PMID: 38781542.
- Sewastjanow-Silva M, Xiao L, Gonzalez GN, Wang X, Hofstetter W, Swisher S, Mehran R, Sepesi B, Bhutani MS, Weston B, Coronel E, Waters RE, Rogers JE, Smith J, Lyons L, Reilly N, Yao JC, Ajani JA, Murphy MB. Chemotherapy Plus Atezolizumab Pre- and Post-Resection in Localized Esophageal or Gastroesophageal Junction Adenocarcinomas: A Phase I/II Single-Arm Study. Cancers (Basel) 16(7), 2024. e-Pub 2024. PMID: 38611056.
- Yamashita K, Sewastjanow-Silva M, Yoshimura K, Rogers JE, Rosa Vicentini E, Pool Pizzi M, Fan Y, Zou G, Li JJ, Blum Murphy M, Gan Q, Waters RE, Wang L, Ajani JA. SMARCA4 Mutations in Gastroesophageal Adenocarcinoma: An Observational Study via a Next-Generation Sequencing Panel. Cancers (Basel) 16(7), 2024. e-Pub 2024. PMID: 38610978.
- Pabon, CM, Xiao, L, Badgwell, BD, Mansfield, PF, Ikoma, N, Sewastjanow-Silva, M, Lee, JH, Bhutani, M, Weston, B, Coronel, E, Smith, GL, Holliday, EB, Tian, J, Das, P, Minsky, B, Waters, R, Estrella, JS, Li, JJ, Ajani, JA, Blum Murphy, M. Neoadjuvant dual checkpoint inhibition followed by immune-chemoradiation in patients with resectable gastric adenocarcinoma. Journal of Clinical Oncology 42(16), 2024. e-Pub 2024.
- Booth AL, Voltaggio L, Waters R, Goldblum J, Feely MM, Agostini-Vulaj D, Pezhouh M, Gonzalez RS. Lobular capillary hemangioma (pyogenic granuloma) of the gastrointestinal tract: Clinicopathologic analysis of 34 cases. Am J Clin Pathol 160(4):411-416, 2023. e-Pub 2023. PMID: 37289424.
- Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, Wang S, Huo L, Wang Y, Wang R, Pool Pizzi M, Ma L, Shao S, Sewastjanow-Silva M, Waters R, Chatterjee D, Liu B, Shanbhag N, Peng G, Calin GA, Mazur PK, Hanash SM, Ishizawa J, Hirata Y, Nagano O, Wang Z, Wang L, Xian W, McKeon F, Ajani JA, Song S. Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment. Gut 72(4):624-637, 2023. e-Pub 2023. PMID: 36002248.
- Rogers JE, Sewastjanow D Silva M, Waters RE, Ajani JA. Pharmaceutical advances in the treatment of gastric adenocarcinoma. Expert Opin Pharmacother 23(5):611-621, 2022. e-Pub 2022. PMID: 35098851.
- Sewastjanow-Silva, M, Yamashita, K, Rosa Vicentini, E, Hirschmann, M, Pizzi, M, Trail, A, Waters, R, Rogers, JE, Ajani, JA. Nivolumab with or without chemotherapy for metastatic gastroesophageal cancers and future perspectives. Expert review of anticancer therapy 22(11):1177-1181, 2022. e-Pub 2022. PMID: 36266061.
- Hao D, He S, Harada K, Pizzi MP, Lu Y, Guan P, Chen L, Wang R, Zhang S, Sewastjanow-Silva M, Abdelhakeem A, Shanbhag N, Bhutani M, Han G, Lee JH, Zhao S, Weston B, Blum Murphy M, Waters R, Estrella JS, Roy-Chowdhuri S, Gan Q, Lee JS, Peng G, Hanash SM, Calin GA, Song X, Zhang J, Song S, Wang L, Ajani JA. Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma. Gut 70(11):2055-2065, 2021. e-Pub 2021. PMID: 33334899.
- Abdelhakeem AA, Wang X, Waters R, Patnana M, Estrella JS, Blum Murphy M, Trail AM, Lu Y, Devine CE, Ikoma N, Das P, Badgwell BD, Rogers JE, Ajani JA. Preoperatively Treated Diffuse-Type Gastric Adenocarcinoma: Glucose vs. Other Energy Sources Substantially Influence Prognosis and Therapy Response. Cancers (Basel) 13(3):1-10, 2021. e-Pub 2021. PMID: 33498613.
- Waters R, Horvai A, Greipp P, John I, Demicco EG, Dickson BC, Tanas MR, Larsen BT, Ud Din N, Creytens DH, Bahrami A, Doyle LA, Jo VY, Al-Ibraheemi A, Thway K, Jenkins SM, Siontis B, Folpe A, Fritchie K. Atypical lipomatous tumour/well-differentiated liposarcoma and de-differentiated liposarcoma in patients aged = 40 years: a study of 116 patients. Histopathology 75(6):833-842, 2019. e-Pub 2019. PMID: 31471922.
- Obeid RA, Hoppe DJ, Dafashy TJ, Waters R, Tarry SE. Cholesterol Granuloma of the Abdominal Wall: An Unusual Finding in the Setting of Renal Cell Carcinoma. Urol Case Rep 13:160-161, 2017. e-Pub 2017. PMID: 28593146.
- Waters R, Xie Y, Dong J, Huang G, Soloway R, Hadidi K, Lohman E, Hu P. Investigating Predictive Models Based on Circulating Cell-free INK4A DNA Methylation, Alpha-fetoprotein, Platelet Count, and Age for Diagnosis and Prognosis of Hepatocellular Carcinoma. J Clin Pathol Microbes 1(1):1-6, 2016. e-Pub 2016.
- Waters R, Agarwal A, Tan D. A Case Report of Colonic Perforation Caused by Cytomegalovirus-induced Colitis. Am J Digest Dis 2(2):106-110, 2015. e-Pub 2015.
- Chao C, Buteau A, Waters R, Boroumand N. Metastatic Carcinoma Arising From Fibroadenoma of the Breast. Int J Cancer Oncol 1(1):1-3, 2014. e-Pub 2014.
Review Articles
- Bhosale H, Shah R, Morani R, Waters R, Chu L, Virarkar M. Gallbladder neuroendocrine neoplasms: a review. Abdominal Radiology 51(5):2341-2352, 2025. e-Pub 2025. PMID: 41021016.
- Li, JJ, Rogers, JE, Waters, R, Gan, Q, Blum Murphy, M, Ajani, JA. Evolution of Therapeutics for Locally Advanced Upper Gastrointestinal Adenocarcinoma. Cancers 17(8), 2025. e-Pub 2025. PMID: 40282483.
- Rogers JE, Gan Q, Waters RE, Horak AA, Ajani JA. Targeted and combination immunotherapies using biologics for gastric cancer: the state-of-the-art. Expert Opin Biol Ther 2024(4):1-11, 2024. e-Pub 2024. PMID: 39315517.
- Vulasala SS, Virarkar M, Gopireddy D, Waters R, Alkhasawneh A, Awad Z, Maxwell J, Ramani N, Kumar S, Onteddu N, Morani AC. Small Bowel Neuroendocrine Neoplasms-A Review. J Comput Assist Tomogr 48(4):563-576, 2024. e-Pub 2024. PMID: 38110305.
- Padmanabhan Nair Sobha R, Jensen CT, Waters R, Calimano-Ramirez LF, Virarkar MK. Appendiceal Neuroendocrine Neoplasms: A Comprehensive Review. J Comput Assist Tomogr 48(4):545-562, 2024. e-Pub 2024. PMID: 37574653.
- Daoud T, Morani AC, Waters R, Bhosale P, Virarkar MK. Diagnostic Approaches to Neuroendocrine Neoplasms of Unknown Primary Site. J Comput Assist Tomogr 48(4):588-600, 2024. e-Pub 2024. PMID: 37876246.
- Menendez-Santos M, Gonzalez-Baerga C, Taher D, Waters R, Virarkar M, Bhosale P. Endometrial Cancer: 2023 Revised FIGO Staging System and the Role of Imaging. Cancers 16(10):1869, 2024. e-Pub 2024. PMID: 38791948.
- Menendez-Santos, M, Gonzalez-Baerga, C, Taher, D, Waters, R, Virarkar, M, Bhosale, PR. Endometrial Cancer. Cancers 16(10), 2024. e-Pub 2024. PMID: 38791948.
- Rogers JE, Yamashita K, Sewastjanow-Silva M, Trail A, Waters RE, Ajani J. Human Epidermal Growth Factor Receptor-2 Gastric Adenocarcinoma: Expanding Therapy of a Recognized Target. Cancers (Basel) 15(21), 2023. e-Pub 2023. PMID: 37958354.
- Rogers JE, Yamashita K, Sewastjanow-Silva M, Rosa Vicentini E, Waters R, Ajani JA. Nivolumab combination therapy as first-line treatments for unresectable, advanced or metastatic esophageal squamous cell carcinoma. Expert Rev Anticancer Ther 23(6):565-571, 2023. e-Pub 2023. PMID: 37122102.
- Li JJ, Rogers JE, Yamashita K, Waters RE, Blum Murphy M, Ajani JA. Therapeutic Advances in the Treatment of Gastroesophageal Cancers. Biomolecules 13(5), 2023. e-Pub 2023. PMID: 37238666.
- Calimano-Ramirez LF, Daoud T, Gopireddy DR, Morani AC, Waters R, Gumus K, Klekers AR, Bhosale PR, Virarkar MK. Pancreatic acinar cell carcinoma: A comprehensive review. World J Gastroenterol. 2022 Oct 28;28(40):5827-5844 28(40):5827-5844, 2022. e-Pub 2022. PMID: 36353206.
- Virarkar M, Vulasala SS, Gopireddy D, Morani AC, Daoud T, Waters R, Bhosale P. Neuroendocrine Neoplasms of the Female Genitourinary Tract: A Comprehensive Overview. Cancers (Basel) 14(13), 2022. e-Pub 2022. PMID: 35804996.
- Virarkar M, Vulasala SS, Morani AC, Waters R, Gopireddy DR, Kumar S, Bhosale P, Lall C. Neuroendocrine Neoplasms of the Gynecologic Tract. Cancers (Basel) 14(7):1835, 2022. e-Pub 2022. PMID: 35406607.
- Rogers JE, Sewastjanow-Silva M, Waters RE, Ajani JA. Esophageal cancer: emerging therapeutics. Expert Opin Ther Targets 26(2):107-117, 2022. e-Pub 2022. PMID: 35119973.
Professional Educational Materials
- Waters R. Gastrointestinal Pathology Society Case of the month (July 2020). Gastrointestinal Pathology Society, 2020.
- Waters R, Fritchie K. Mayo Clinic Pathways Weekly Pathology Case Study [Blog Post], 2016.
Abstracts
- Han X, Yamashita K, Pizzi MP, Cho KS, Dai E, Yu K, Liu Y, Dai Y, Chu T, Sewastjanow-Silva M, Yoshimura H, Fan Y, Waters R, Gan Q, Yin F, Dhar SS, Martins I, Willis J, Murphy MB, Li J, Badgwell BD, Morris VK, Overman MJ, Wang L, Ajani JA. Spatially organized transcriptional programs and tumor-stroma interfaces shape immunotherapy response in microsatellite instability-high gastrointestinal cancers [abstract]. Cancer Research 2026(86):4947, 2026. e-Pub 2026.
- Lubo Julio IC, Liu Y, Hernandez S, Serrano AG, Lu W, Kostousov L, Barnes S, Khan K, Colbert K, Chu Y, Liu Y, Waters R, Davis JL, Mansfield PF, Wang L, Solis Soto LM. Neighborhood analyses in nerve fiber-associated tumor regions in hereditary diffuse gastric cancer [abstract]. Cancer Res 2026 Cancer Res 2026;86(7 Suppl):Abstract nr 6229, 2024. e-Pub 2024.
- Sewastjanow M, Yamashita K, Iwata K, Moran D, Elsouda D, Pizzi M, Vicentini, Shanbhag N, Ta A, Waters R, Chatterjee D, Ajani J. Claudin 18.2 Expression Prevalence, Prognostication, and Clinical Variables in Gastric and Gastroesophageal Junction Adenocarcinoma Patient Samples. Cancer Res 83(2023):2141, 2023. e-Pub 2023.
- Muftah AA, Waters R, Wang L, Zhang HC. Vanishing Bile Duct Syndrome in the Setting of Newly Diagnosed Hodgkin Lymphoma. The American Journal of Gastroenterology 117(10S):p e1992-e1993, October 2022, 2022. e-Pub 2022.
- Waters R, Taggart M, Malpica A, Mansfield P, Raghav K. Unifocal Peritoneal Malignant Mesothelioma as Initial Presentation of Lynch Syndrome: A Case Report and Brief Review. American Journal of Clinical Pathology, Volume 158, Issue Supplement_1, November 2022, Page S69 158(1):S69, 2022. e-Pub 2022.
- Taherian M, Waters R, Foo WC, Maru D, Abraham S, Rashid A, Wang H, Wei D, Taggart M, Chatterjee D. Blinded Histologic Review to Classify Grade 3 Pancreatic Epithelial Neuroendocrine Neoplasms Shows Only Slight Correlation Among Experienced Gastrointestinal Pathologists. USCAP 2022 Abstracts: Pancreas, Gallbladder, Ampulla, and Extra-Hepatic Biliary Tree (1111-1144). Modern Pathology, suppl.2. 2022/03//;35:1317-1354, 2022. e-Pub 2022. PMID: 35302097.
- Tong YT, Foo WC, Waters RE, Rashid A, Abraham S, Chatterjee D, Taggart MW. Defining Amphicrine Carcinoma of the Gastrointestinal Tract: A Single Institutional Experience. Mod Pathol 35(2022):493-639, 2022. e-Pub 2022. PMID: 35302089.
- Bakhshwin A, Waters R, Plesec T. Gastric Margin Status at Frozen Section: Discrepancies between Representative Vs. in Total Sections. Mod Pathol 32(2019):1-164, 2019. e-Pub 2019. PMID: 30886291.
- Waters R, Horvai A, Greipp P, John I, Demicco EG, Dickson BC, Tanas MR, Larsen BT, Ud Din N, Creytens DH, Bahrami A, Doyle LA, Jo VY, Al-Ibraheemi A, Folpe A, Fritchie K. Atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma in patients <40 years: A study of 103 patients. Mod Pathol 31(2018):18-41, 2018. e-Pub 2018. PMID: 29551782.
- Waters R, Xie Y, Huang G, et al. Investigating Predictive Models Based on Circulating Cell-free INK4A DNA Methylation, Alpha-fetoprotein, Platelet Count, and Age for Diagnosis and Prognosis of Hepatocellular Carcinoma. Mod Pathol 29(2016):427A, 2016. e-Pub 2016.
- Waters R, Singh G, Eltorky M, Nishi S. Anatomic Distribution of Smoking Related Interstitial Fibrosis (SRIF) in Lung Lobectomy/ Pneumonectomy Specimens. Modern Pathology 28(2015):492A, 2015. e-Pub 2015.
- Waters RE, McHugh K, Fang M, Gu D, Lu H, Shi J, Downs-Kelly E, Roopkumar J, Sohai D, Allende D. Post-neoadjuvant Pancreatic Ductal Adenocarcinoma: Tumor burden, not tumor size, may predict outcome. Mod Pathol 32(2019):1-60. PMID: 30886283.
Book Chapters
- Waters R. Pleural Effusions. In: Pathology of Pleura and Mediastinum. Springer, 2018.
- Waters R. Viral Infections, Pleural. In: Pathology of Pleura and Mediastinum. Springer, 2018.
- Waters RE. The Stomach. In: College of American Pathologists Manual of Gastrointestinal, Liver and Pancreatobiliary Pathology. College of American Pathologists.
Books (edited and written)
- Hipp J, Bauer T, Bui M, Cornish T, Evans A, Glassy E, McGee R, Murphy D, O'Neill D, Pantanowitz L, Parwani A, Rampy B, Salama M, Waters R. College of American Pathologists Pathology Resource Guide: Digital Pathology. College of American Pathologists, 2017.
- Hipp J, Bauer T, Bui M, Cornish T, Evans A, Glassy E, Murphy D, Pantanowitz L, Parwani A, Rampy B, Salama M, Waters R. College of American Pathologists Pathology Resource Guide: Digital Pathology. College of American Pathologists, 2016.
Patient Reviews
CV information above last modified August 27, 2026