Robert L. Satcher, M.D., Ph.D.
Department of Orthopaedic Oncology, Division of Surgery
About Dr. Robert L. Satcher
Dr. Robert L. Satcher is an Associate Professor in the Department of Orthopaedic Oncology at The University of Texas MD Anderson Cancer Center in Houston, Texas. He specializes in the treatment of skeletal metastatic disease, soft tissue sarcoma, technology applications for improving surgical outcomes, teleoncology, and intra operative navigation. Dr. Satcher is a former Astronaut, having served as a mission specialist who visited the International Space Station. Dr. Satcher is leading institutional efforts to establish the clinical enterprise for virtual care at MDACC. Additionally, his work with MD Anderson’s Global Oncology enterprise is focused on building relationships with international healthcare partners that will lead to the construction of a Cancer Center in sub-Saharan Africa. Dr. Satcher co-founded the eHealth Research Institute (eHRI), a collaborative endeavor between Rice University, the National Space Biomedical Research Institute, and MD Anderson Cancer Center, to bring together physicians with academic and industry researchers to improve access to specialized health care using the latest in research and technology. Dr. Satcher is a member of numerous professional organizations including the American Academy of Orthopaedic Surgery, Musculoskeletal Tumor Society, National Comprehensive Cancer Network, American Telemedicine Association, American Association of Cancer Research, Doctors United in Medical Missions, and the Orthopaedic Research Society.
Present Title & Affiliation
Primary Appointment
Professor, Department of Orthopaedic Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas
Associate Professor, Department of Orthopedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Adjunct Professor, Ken Kennedy Institute of Information Technology, Rice University, Houston, TX
Education & Training
Degree-Granting Education
| 1994 | Harvard Medical School, Boston, Massachusetts, US, MD |
| 1993 | Massachusetts Institute of Technology, Boston, Massachusetts, US, Chemical Engineering, Ph.D |
| 1986 | Massachusetts Institute of Technology, Cambridge, Massachusetts, US, Chemical Engineering, BS |
Postgraduate Training
| 2008-2008 | Robotic Arm Training Fellowship, Japanese Space Agency, JAXA, Tskuba |
| 2008-2010 | Extravehicular Activity Training, Neutral Buoyancy Laboratory, NASA - Johnson Space Center, Houston, Texas |
| 2007-2007 | Astronaut Training, Robotic Arm Training Fellowship, Canadian Space Agency, Quebec |
| 2004-2006 | Astronaut Candidate Basic Training, NASA - Johnson Space Center, Houston, Texas |
| 2000-2001 | Clinical Fellowship, Orthopaedic Oncology Surgery Clinical, Enneking Fellow, University of Florida - Shands Hospital Center, Gainesville, Florida |
| 1997-2000 | Research Fellowship, Bone Biology and Endocrinology Laboratory, UCSF, San Francisco, California |
| 1997-1998 | Research Fellowship, Bone Biology and Cellular Biomechanics, University of California - Berkeley and UCSF, Berkeley, California |
| 1995-2000 | Clinical Residency, Orthopaedic Surgery Resident, University of California, San Francisco, California |
| 1994-1995 | General Surgery Internship, Intern, University of California, San Francisco, California |
| 1993-1994 | Research Fellowship, Vascular Pathology and Fluid Dynamics, Harvard Medical School, MA and MIT, Cambridge, Massachusetts |
| 1993-1993 | Clinical Fellowship, Surgery and Internal Medicine, Schweitzer Fellow, Albert Schweitzer Hospital, Lambarane |
| 1984-1985 | Engineer Internship, Polymer Chemistry, DuPont Internship, El DuPont deNemours & Co, Camden, South Carolina |
| 1982-1983 | Engineer Internship, Rheological Studies of Polymer Melts, Polymer Products Division, DuPont Internship, El DuPont deNemours & Co, Camden, South Carolina |
Licenses & Certifications
| 2019 | Drug Enforcement Agency |
| 2013 | American Board of Orthopaedic Surgery |
| 2005 | Texas Medical License |
| 2003 | American Board of Orthopaedic Surgery |
| 2001 | Illinois Medical License |
| 1996 | Medical Board of California |
| 1995 | National Board of Medical Examiners |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Department of Orthopedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2017
Clinical Assistant Professor, Department of Orthopaedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007 - 2011
NASA Mission Specialist Astronaut, NASA - Johnson Space Center, Houston, TX, 2004 - 2011
Assistant Professor, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 2002 - 2008
Assistant Professor, Department of Orthopaedic Surgery, Children's Memorial Hospital, Chicago, IL, 2001 - 2008
Attending Physician, Department of Orthopaedic Oncology, Northwestern Memorial Hospital - Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 2001 - 2008
Assistant Professor, Department of Orthopaedic Surgery, Northwestern University, The Feinberg School of Medicine, Chicago, IL, 2001 - 2008
Adjunct Professor, Department of Institute for Bionanotechnology in Medicine, Northwestern University Medical Center, Chicago, IL, 2001 - 2008
Instructor, Department of Orthopaedic Surgery, University of Florida - Shands Hospital, Gainesville, FL, 2000 - 2001
Other Professional Positions
Chairman, Board of Trustees, Voorhees College, Denmark, SC, 2016 - 2020
User Panel Member, National Space Biomedical Research Institute, Houston, TX, 2013 - 2019
Board Member, ConvergeUS, Washington, DC, 2012 - 2014
Vice Chairman, Board of Trustees, Voorhees College, Denmark, SC, 2011 - 2016
District IV Representative, National Selection Committee, Massachusetts Institute of Technology Alumni Association, Cambridge, MA, 2008 - 2011
Co-chairman, Faculty Diversity Advisory Panel, Massachusetts Institute of Technology, Cambridge, MA, 2002
Orthopaedic Surgery Representative, Tumor Board, Children's Memorial Hospital, Chicago, IL, 2001 - 2004
Director, Sarcoma Board, Northwestern Memorial Hospital, Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 2001 - 2004
Director, Faculty Diversity Self Study, Harvard Medical School, Boston, MA, 1993
Member, Course Evaluation Committee, Massachusetts Institute of Technology, Cambridge, MA, 1992
Member, Steering Committee, Harold Amos Biomedical Sciences Committee, Harvard Medical School, Boston, MA, 1990 - 1994
Member, Harvard - MIT Health Sciences and Technology Admissions Committee, Harvard Medical School (HMS), Boston, MA, 1989 - 1993
Extramural Institutional Committee Activities
Member, Diversity, Equity and Inclusion Committee, Division of Surgery, The University of Texas MD Anderson Cancer Center, 2021 - 2023
Officer, Quality Improvement Officer, Orthopaedic Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Executive Committee, Virtual Care and Access, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, International Virtual Care Development Committee, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, Search Committee for Division Head, Clinical Pathology, The University of Texas MD Anderson Cancer Center, 2020 - Present
Officer, Safety and Quality, Orthopaedic Oncology, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, Innovation Steering Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Member, Credentials Committee for the Medical Staff, The University of Texas MD Anderson Cancer Center, 2017
Senator, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2016 - 2020
Member, Faculty Academic Review Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Faculty Representative, Sarcoma Survivorship Committee, Dept. of Orthopaedic Oncology, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, eHealth Advisory Board, eHealth Technology Program, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Pelvic Sarcoma of Excellence Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Division of Surgery Cancer Network Operations Committee, The University of Texas MD Anderson Cancer Center, 2014 - Present
Member, Division of Surgery Educational Initiatives Committee, The University of Texas MD Anderson Cancer Center, 2012 - Present
Africa Committee, Global Academic Programs and Business Development, The University of Texas MD Anderson Cancer Center, 2011 - Present
Chairman, Telemedicine and Telesurgery for Regional Care Centers, The University of Texas MD Anderson Cancer Center, 2011 - 2018
Editorial Activities
Editor, Regenerative Engineering and Transnational Medicine, 2015 - Present
Honors & Awards
| 2021 - 2024 | AIMBE College of Fellows, American Institute for Medical and Biological Engineering |
| 2020 - 2021 | 1000 Inspiring Black Scientists in America, Cell Mentor: The Community of Scholars |
| 2020 - 2024 | Association of Bone and Joint Surgeon Member, Association of Bone and Joint Surgeons |
| 2015 | AT&T’s 2015 African American History Calendar |
| 2015 | 28 Days Game Changers Past & Present, AT&T |
| 2014 | The HistoryMakers |
| 2014 | AICHE MAC Eminent Engineer Award, Georgia Aerospace Inc |
| 2013 | Business/Civic Leadership Forum Fellow, Center for Houston's Future |
| 2013 | First Annual Strong Men & Women in Virginia History, Library of Virginia and Dominion Energy |
| 2012 | Honorary Doctorate of Science, Voorhees College |
| 2012 | Honorary Doctorate of Science, St. Paul's College |
| 2010 | Finalist, Tuskegee University Presidency Search |
| 2009 | Mission Specialist Astronaut, STS - 129/ULF3 Space Shuttle Atlantis Mission |
| 2009 | American-British-Canadian (ABC) Fellow, American Orthopaedic Association (AOA) |
| 2008 | Selected for "America's Top Surgeons", Consumers' Research Council of America |
| 2008 | Selected for Who's Who, Black Houston |
| 2008 | Leadership Fellows Program, Class of 2008-2009, AAOS |
| 2004 | Crain's 40 under 40 Laureate, Crain's Business Journal, Chicago, IL |
| 2002 - 2003 | Career Development Award, Orthopaedic Research and Education Foundation |
| 1997 | Merck - UNCF Scholar, Merck - UNCF Postdoctoral Fellowship, Merck, Inc |
| 1991 | Best Research Award for "The Distribution of fluid forces on arterial endothelial cells", American Society of Mechanical Engineers |
| 1986 | Albert G. Hill Award, Dean of Engineering Award, Massachusetts Institute of Technology |
| 1985 | Monsanto Award, Dean of Engineering Award for highest GPA, Massachusetts Institute of Technology |
| 1985 | Tau Beta Pi Engineering Honor Society, Massachusetts Institute of Technology |
| 1984 | National Merit Scholar, Summer Education Enrichment Program Scholar, Medical College of Georgia |
| 1982 - 1986 | Scholastic Collegiate Scholarships, DuPont de Nemours Inc |
| 1982 | Valedictorian, Denmark-Olar High School |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2022. Panelist. Conference. UT MD Anderson Cancer Network. Houston, TX, US.
- 2022. Space Medicine and Surgery. Conference. UT McGovern School of Medicine. Houston, TX, US.
- 2022. Opening Keynote Speaker. Conference. UT MD Anderson Cancer Center. Houston, TX, US.
- 2022. Black Men in White Coats Panel Presentation. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2022. You Never Know Who You Will Inspire: A Candid Discussion with STS-129 Mission Specialists. Conference. Space Center Houston. Houston, TX, US.
- 2022. Black History Month: TikTok Series. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2022. One former NASA astronaut's view on what is next in space exploration. Conference. PBS News Hour. Houston, TX, US.
- 2021. Black History Month: Celebrating Excellence. Conference. University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2020. Space Center Houston: Virtual Camp Out. Conference. Space Center Houston. Houston, TX, US.
- 2020. Black History Month Heroes: Retired Astronaut Dr. Robert Satcher. Conference. Fox 26's Isiah Carey's "The Isiah Factor" TV show. Houston, TX, US.
- 2019. Mentoring to Medicine: Joint Symposium for MD Anderson Cancer Center and 100 Black Men of Houston. Conference. MD Anderson & 100 Black Men of Houston. Houston, TX, US.
- 2019. Invited Panelist: Beyond the Game: Successful choices for life. Conference. Yates High School - Jonathan Martin w/Fox 26 News. Houston, TX, US.
- 2019. Invited Panelist: 2019 Boule Western Regional Conference, Social Action Seminar. Conference. Nu Boule. Houston, TX, US.
- 2018. Blasting off to new heights--careers in STEM. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2017. Reciprocal Technology Transfer Between Space and Terrestrial Industry. Conference. SpaceCom Conference. Houston, TX, US.
- 2017. Changes in Cancer Care resulting from the Affordable Care Act. Conference. University of Houston. Houston, TX, US.
- 2015. Telemedicine and Cancer Care. Conference. Medical World Americas Conference and Expo. Houston, TX, US.
- 2014. Keynote Address: Countermeasures to preserve musculoskeletal health in zero gravity. Conference. BioScience Research Center; Rice Univeristy. Houston, TX, US.
- 2014. Technology: the Use of eHealth for Cancer Care at a Distance. Conference. Baylor College of Medicine. Houston, TX, US.
- 2014. Keynote Address. Conference. Channelview High School. Houston, TX, US.
- 2013. Houston's Evolving Transnational Research Hub. Conference. Texas CEO Magazine. Houston, TX, US.
- 2013. eHealth Research Institute Overview. Conference. BioScience Research Collaborative. Houston, TX, US.
- 2013. Osteocyte Biology in Space Workshop. Conference. The Rolanette and Berdon Lawrence Bone Disease Program of Texas, BCM and MD Anderson Cancer Center. Houston, TX, US.
- 2013. Challenges for Increasing Access to Cancer Care in the Digital Era Using Telemedicine. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2012. Operating rooms and orbits: medical and surgical care for astronauts. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2012. Featured speaker, Teamwork in exploration. Conference. Rice University and MD Anderson Cancer Center. Houston, TX, US.
- 2012. Robotics, Medicare, and Space Exploration. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2012. Invited Lecture: Overview of the Telehealth Research Institute. Conference. Greater Houston Partnership. Houston, TX, US.
- 2012. Guest Lecture: Why would you do that? An Oncologist experience with space flight?. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2012. The Future of Telemedicine. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2011. Keynote Address - Challenges and Solutions in Medicine in the 21st Century. Conference. The Health Museum. Houston, TX, US.
- 2011. Keynote Address. Conference. Houston Orthopaedic Society. Houston, TX, US.
- 2010. Invited Panelist: International Space Medicine Summit 2010, Highest Priorities for Countermeasures Research. Conference. James A. Baker III Institute for Public Policy, Rice University. Houston, TX, US.
- 2009. Keynote Address: STS-129: What does an orthopaedic surgeon do in outer space?. Conference. Korean American Medical Association. Houston, TX, US.
- 2009. Pan American Robotic Oncology Symposium (PAROS), Keynote Address: Current Status of Robotic Oncology: Where Are We and Where Are We Going. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2007. Cell-cell contact regulates MTA1 and other genes in prostate cancer bone metastasis formation. Conference. MD Anderson Cancer Center. Houston, TX, US.
- 2006. Orthopaedic Surgery Grand Rounds: Musculoskeletal Health in Space Flight. Conference. Baylor College of Medicine. Houston, TX, US.
Regional Presentations
- 2022. OITE COURSE 15. Conference. JRGOS. Townson, MD, US.
- 2021. Article: Experts in oncology help advise NASA on space radiation health standard for astronauts. Conference. Healio, US.
- 2021. Presentation: Space Flight, the ISS & Finding ways to solve today's problems. Conference. Middle School Summer Engineering Academy. Virtual Presentation, US.
- 2020. Maintaining Human Experience in a New Era of Virtual Connection in Healthcare. Conference. The Beryl Institute, US.
- 2020. ARTICLE on www.thegrio.com: NASA almost sent first Black man into space, new documentary reveals. Conference. The Grio, US.
- 2020. 'Black In Space' Explores NASA's Small Steps And Giant Leaps Toward Equality. Conference. NPR (National Public Radio, Inc.), US.
- 2018. Osteoblast Inhibition Promotes Osteolytic Lesions In Renal Cell Bone Metastasis. Conference. Orthopaedic Research Society. New Orleans, LA, US.
- 2017. Improving Health and Wellness: Addressing Community, Caution and Change. Conference. 100 Black Men. New Orleans, LA, US.
- 2014. Orthopaedics and Astronauts: An Evolving Story. Conference. University of Texas Medical Branch at Galveston. Galveston, TX, US.
- 2014. Using Innovative Information Technology to Advance Cancer Survivorship Research. Conference. MD Anderson Cancer Center, TX, US.
- 2010. Keynote Address. Conference. Surgical Innovations 2010, Expanding Surgical Frontiers. Austin, TX, US.
- 2008. Keynote Address. Conference. National Institute of Science and Beta Kappa Chi Scientific Honor Society, 65th Annual Meeting. Dallas, TX, US.
National Presentations
- 2022. Orthopedics and Orbits. Conference. 64th Annual Rocky Mountain Traumatological Society. Virtual Presentation, US.
- 2021. Targeting the Osteogenic Niche for Preventing Kidney Cancer Bone Metastasis Progression. Invited. Kidney Cancer Research Summit 2021. Philadelphia, PA, US.
- 2021. Renal cell carcinoma bone metastasis treatment resistance is partly dependent on osteocyte apoptosis. Conference. MSTS Annual Meeting. Baltimore, MD, US.
- 2021. Denosumab and Bisphosphonates did not improve Patient Survival after Bone Surgery for Metastatic Renal Cell Carcinoma. Conference. MSTS Annual Meeting. Baltimore, MD, US.
- 2021. En Bloc Resection and Intercalary Endoprosthetic Reconstruction for Palliative Treatment of Patients with Diaphyseal Long Bone Metastases. Conference. MSTS Annual Meeting. Baltimore, MD, US.
- 2021. Long Bone Allograft Reconstructions after Oncologic Resection: Does Degree of Cortical Contact Affect Healing Time?. Conference. MSTS Annual Meeting. Baltimore, MD, US.
- 2021. Denosumab and Bisphosphonates did not improve Patient Survival after Bone Surgery for Metastatic Renal Cell Carcinoma. Conference. ASBMR 2021 Annual Meeting. San Diego, CA, US.
- 2020. Telemedicine and Telesurgery in Cancer Care. Invited. Virtual Healthcare in the Mainstream Symposium, US.
- 2020. Teamwork, Innovation, and Transcendence. Invited. Vertex Pharmaceuticals, US.
- 2020. Journey and Power of Teamwork. Invited. Twitter. Houston, TX, US.
- 2018. Medical care for deep space exploration. Conference. Bibb County Medical Society. Macon, GA, US.
- 2018. High Grade Intramedullary Osteosarcoma: Does Histologic Subtype Affect Outcome. Invited. Musculoskeletal Tumor Society. New York, NY, US.
- 2017. Osteoblast inhibition is a novel mechanism for development of osteolytic lesions in renal cell bone metastasis. Invited. Musculoskeletal Tumor Society. Denver, CO, US.
- 2017. Outcomes for reamer irrigator aspirator (RIA)use in metastatic femoral intramedullary nails compared to standard reamer. Invited. Musculoskeletal Tumor Society. Denver, CO, US.
- 2016. The Role of Osteoblasts in the Osteolyctic Bone Metastasis of Renal ell Carcinoma. Conference. Musculoskeletal Tumor Society. Detroit, MI, US.
- 2016. Telemedicine and Social Media for Cancer Cacre. Invited. American Academy of Orthopaedic Surgeons. Orlando, FL, US.
- 2016. Outcomes of Distal Femur Replacement with or without Patellar Resurfacing After Resection of the Distal Femur. Invited. American Academy of Orthopaedic Surgeons. Orlando, FL, US.
- 2015. The Outcome of patients with metastatic giant cell tumor of bone. Invited. Connective Tissue Oncology Society. Salt Lake City, UT, US.
- 2014. The Accuracy and Clinical Utility of Intraoperative Frozen Section Analysis in Open Biopsy of Bone. Invited. Muskuloskeletal Tumor Society. Houston, TX, US.
- 2014. The Treatment of Diaphyseal Femur Fractures in the metastatic renal cell carcinoma. Invited. Muskuloskeletal Tumor Society. Houston, TX, US.
- 2014. Chondrosarcoma of the Sacrum: A review of 27 cases at a single institution. Conference. Muskuloskeletal Tumor Society. Houston, TX, US.
- 2014. Non-Radiographic Risk Factors Differentiating Atypical Lipomatous Tumors and Lipomas. Invited. Muskuloskeletal Tumor Society. Houston, TX, US.
- 2014. The Bone Metastatic Potential of 786-O Renal Cell Carcinoma Cells is Increased by Cadherin 11 Expression and Growth in 3D Culture. Invited. Muskuloskeletal Tumor Society. Houston, TX, US.
- 2014. Case Unknowns and Presentation. Invited. Muskuloskeletal Tumor Society. Houston, TX, US.
- 2014. Taskforce Member: Health Care and Social Media. Invited. Facebook. San Francisco, CA, US.
- 2014. The Bone Metastatic Potential of 786-0 Renal Cell Carcinoma Cells is Increased by Cadherin 11 Expression and Growth in 3D Culture. Invited. Global Academic Programs 2014. Seoul.
- 2014. Challenges and Opportunities for the delivery of Cancer Care using Teleoncology. Invited. Global Academic Programs 2014. Seoul.
- 2013. Schweitzer Leadership Award Ceremony and Conference. Invited. Keynote Address. Boston, MA, US.
- 2013. High Mechanical Failure Rate of Repiphysis Expandable Endoprotsthesis. Conference. Musculoskeletal Tumor Society Annual Meeting. San Francisco, CA, US.
- 2013. Limb Salvage/Septic and Other Complications. Invited. Musculoskeletal Tumor Society Annual Meeting. San Francisco, CA, US.
- 2013. Radiation and Chemotherapy for Extraosseous osteosarcoma. Conference. Musculoskeletal Tumor Society Annual Meeting. San Francisco, CA, US.
- 2013. Tibial Growth Disturbance Following Distal Femur Resection with Expandable Endoprosthesis Reconstruction. Conference. Musculoskeletal Tumor Society Annual Meeting. San Francisco, CA, US.
- 2013. Increased Expression of Cadherin 11 in Bone-Derived 786-O Renal Cell Carcinoma Cells. Conference. Musculoskeletal Tumor Society Annual Meeting. San Francisco, CA, US.
- 2013. Intramedullary nailing of femoral diaphyseal metastases: Is it really necessary to protect the femoral neck?. Conference. Musculoskeletal Tumor Society Annual Meeting. San Francisco, CA, US.
- 2012. Keynote Address, The future of robotic surgery. Invited. RAMSES. Tampa, FL, US.
- 2012. Modular endoprosthetic replacement in limb salvage for malignant distal humeral tumors. Invited. Musculoskeletal Tumor Society Meeting. Tampa, FL, US.
- 2012. Total humeral endoprosthetic replacement following excision of malignant bone tumors. Invited. Musculoskeletal Tumor Society Meeting. Tampa, FL, US.
- 2012. Durability of cephalomedullary nail fixation for treatment of metastatic peritrochanteric femoral lesions. Invited. Musculoskeletal Tumor Society Meeting. Tampa, FL, US.
- 2012. Skeletal and extraskeletal mesenchymal chondrosarcoma: A review of 37 cases. Invited. Musculoskeletal Tumor Society Meeting. Tampa, FL, US.
- 2012. Dedifferentiated chondrosarcoma: A single institution review of 41 cases. Invited. Musculoskeletal Tumor Society Meeting. Tampa, FL, US.
- 2011. Hip Arthroplasty for Proximal Femur Metastases: Does the Length of Stem Matter?. Invited. 2011 Combined Meeting of the CTOS and the MSTS. Chicago, IL, US.
- 2011. Distal Femoral Allograft Composite Reconstruction for Short Proximal Femur Segments Following Sarcoma Resection. (Poster Presentation). Invited. 2011 Combined Meeting of the CTOS and the MSTS. Chicago, IL, US.
- 2011. Recurrence Factors of Pelvic Malignant Bone Tumors (Poster Presentation). Invited. 2011 Combined Meeting of the CTOS and the MSTS. Chicago, IL, US.
- 2011. Poster Presentation, Size Variation of Extremity Atypical Lipomatous Tumors Versus Lipomas. Invited. Combined Meeting of the CTOS and MSTS. Chicago, IL, US.
- 2011. DVT Prophylaxis with Dalteparin for Malignant Tumor Resection. Invited. . American Academy of Orthopaedic Surgeon Annual Meeting. San Diego, CA, US.
- 2011. MIT Scholars Keynote Address: Reducing racial disparities in Stem (Science, Technology, Engineering, and Math). Invited. Massachusetts Institute of Technology. Cambridge, MA, US.
- 2011. Keynote Address. Invited. Vanderbilt University, Martin Luther King Lecture. Nashville, TN, US.
- 2011. Keynote Address: Diversity in space exploration. Invited. Northwestern University Medical Center 32nd Annual MLK Commemoration. Chicago, IL, US.
- 2010. Keynote Address: An alumni perspective on space, medicine, and astronauts. Invited. Harvard Medical School, National Dean’s Council Celebration. Boston, MA, US.
- 2010. Keynote Address. Invited. 20th Annual Baltimore Limb Deformity Course. Baltimore, MD, US.
- 2010. 2010 Joseph M. Healey Address: Bone metastasis. Invited. University of Connecticut School of Medicine and Dental Medicine Convocation, University of Connecticut Health Center. Farmington, CT, US.
- 2010. Keynote Address, Amgen Scholars Symposium. Invited. UCLA. Los Angeles, CA, US.
- 2008. An Experience in Structural Pelvic Allograft Reconstruction after Resection of Malignant Pelvic Bone Tumors. Invited. Musculoskeletal Tumor Society Annual Meeting. Phoenix, AZ, US.
- 2007. Hemangioendothelioma of Bone – Surgical Outcome. Invited. Musculoskeletal Tumor Society 2007 Annual Meeting. St. Louis, MO, US.
- 2007. Keynote address. Conference. 2007 J. R. Gladden Orthopaedic Society Luncheon. San Diego, CA, US.
- 2007. Racial and Ethnic Disparities in Musculoskeletal Health, Issues, Myths and Intervention. Conference. 2007 Annual Meeting of American Academy of Orthopaedic Surgeons. San Diego, CA, US.
- 2006. Keynote address - Leadership in Orthopaedic Surgery: Impacts, Pitfalls, and Challenges. Invited. 2006 Orthopaedic Research and Education Foundation Luncheon for Trustees. Chicago, IL, US.
- 2006. Stromal epithelial crosstalk in prostate cancer bone metastasis modified specific gene test compared to the interaction in primary tumor. Invited. Podium presentation, Orthopaedic Research Society. Chicago, IL, US.
- 2005. Role of physical contact between prostate cancer cells and osteoblasts in prostate cancer bone metastases. Invited. Podium presentation, Musculoskeletal Tumor Society Annual Meeting. Nashville, TN, US.
- 2004. Osteoprogenitor stem cells repel to pulsatile stress in vitro. Invited. American Society for Bone and Mineral Research. Seattle, WA, US.
- 2004. The Influence of Sex and Gender on Musculoskeletal Health, Hunt Valley, MD. Presentation title: Prostate Cancer to Bone: An Under-investigated Problem. Invited. American Academy of Orthopaedic Surgeons (AAOS), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the Office of Research in Women’s Health (ORWH), US.
- 2004. Self-assembling nanofiber matrix for bone regeneration. Invited. American Chemical Society National Meeting. Anaheim, CA, US.
- 2004. The effects of physical contact in cancer bone metastases detected in a novel micropatterned co-culture system. Invited. American Chemical Society National Meeting. Anaheim, CA, US.
- 2003. Surgical consideration in the treatment of cancer patients. Invited. Contemporary Issues in Cancer Rehabilitation, Rehabilitation Institute of Chicago. Chicago, IL, US.
- 2003. Studying cell-cell contact in bone metastasis using a novel co-culture system. Invited. symposium presentation at Musculoskeletal Tumor Society, Annual Meeting. Chicago, IL, US.
- 2003. Hormonal Regulation of Bone Metastases in Breast Cancer. Invited. podium presentation at Musculoskeletal Tumor Society, Annual Meeting. Chicago, IL, US.
- 2001. Reconstruction following resection of tumors about the pelvis. Invited. Connective Tissue Oncology Society, US.
- 2001. Osteoprogenitor cells respond to pulsatile shear stress in vitro. Invited. Bioengineering Seminar, University of California, San Diego Dept. of Bioengineering. San Diego, CA, US.
- 2000. The use of motor evoked potentials to monitor sciatic nerve status during revision total hip arthroplasty. Invited. Presented at The Hip Society Meeting. Boston, MA, US.
- 2000. Osteoblasts in Culture Respond to In Vitro Pulsatile Fluid Flow with Short Term Increases in PGE2 and Long Term Increases in Cell Proliferation. Invited. American Society of Bone and Mineral Research. 22nd Annual Meeting, US.
- 1994. Shear stress induced changes in actin cytoskeleton of endothelial cells. Invited. Annual fall meeting of Biomedical Engineering Society. Tempe, AZ, US.
- 1992. Electron microscopic studies of structural changes in endothelial cells resulting from shear stress. Invited. Presented at the Winter Annual Meeting of the American Society of Mechanical Engineers. Anaheim, CA, US.
- 1991. Structural changes in endothelial cells resulting from shear stress. Invited. Presented at the winter meeting of the Society of Biophysics and Biotheology. Rochester, NY, US.
- 1990. A hypothesis: how arterial cells resist fluid shear stress. Invited. Conference of the Division of Fluid Dynamics, American Physical Society, Cornell University. Ithaca, NY, US.
International Presentations
- 2022. Practice Patterns in the Management of Regional Lymph Node Metastasis in Soft Tissue Sarcoma: A Survey of The Society of Surgical Oncology and Musculoskeletal Tumor Society Membership. Conference. Connective Tissue Oncology Society Annual Meeting. Vancouver, CA.
- 2022. Practice Patterns in the Management of Regional Lymph Node Metastasis in Soft Tissue Sarcoma: A Survey of The Society of Surgical Oncology and Musculoskeletal Tumor Society Membership. Conference. The Connective Tissue Oncology Society. Vancouver, CA.
- 2022. Orthopaedics, Orbits, and Operating Rooms: Translational Applications for Telemedicine and Telesurgery in Cancer Care. Conference. The Association of Bone and Joint Surgeons. Venice, IT.
- 2022. Keynote Speaker: Space Medicine. Invited. International Gastric Cancer Congress 2022. Houston, US.
- 2021. Restoring Hope and Health Across the African Diaspora: Black Health and Wellness Matter. Invited. NMA Community and Public Health Section. New Orleans (Virtual), US.
- 2019. Panel Discussion: Space Medicine and Prevention and Treatment of Diseases. Invited. International Peace Alliance (Space), Chinese Society of Astronautics and China High-Tech Industrialization Association. Zhuhai City, CN.
- 2019. Leveraging technology to improve surgical care for cancer patients. Invited. RAMSES. Cartagena, CO.
- 2018. Clear cell chondrosarcoma: clinical characteristics and treatment outcomes in 19 patients. Conference. Connective Tissue Oncology Society. Rome, IT.
- 2018. High grade intermedullary osteosarcoma: does histologic subtype affect outcome?. Conference. Connective Tissue Oncology Society. Rome, IT.
- 2017. Lessons from NASA: A journey towards becoming a high reliability organization. Invited. Global Conference on Perioperative Medicine. Houston, US.
- 2017. BIGH3 inhibits osteoblasts in renal cell carcinoma bone metastasis. Conference. International Society of Limb Salvage (ISOLS). Kanazawa, JP.
- 2016. Teleoncology in developing countries: MD Anderson Initiatives in Digital Health and Telemedicine. Invited. China International Telemedicine Summit. Beijiing, CN.
- 2016. BIGH3 is a unique and novel mechanism of osteolysis in kidney cancer bone metastasis. Invited. Connective Tissue Oncology Society, PT.
- 2016. Role of osteoblasts in osteolytic bone metastaisis of renal cell carcinoma. Invited. Metastasis Research Society, CN.
- 2016. The use of mobile devices for patient follow-up in Ethiopia. Invited. 10th Annual Stop Cervical, Breast, and Prostate Cancer in Africa Conference. Addis Abbaba, ET.
- 2016. A mobile phone platform for cancer patient evaluation and follow up in SubSaharan Africa. Conference. Global Academic Programs (GAP 2016), BR.
- 2014. Intramedullary Nailing of Femoral Diaphyseal Metastases: Is it Really Necessary to Protect the Femoral Neck?. Conference. Southern Orthopaedic Association Annual Meeting. Beaver Creek, US.
- 2014. Teleoncology: Improving Cancer Care Access with Technology. Invited. The 8th SCCA (Stop Cervical, Breast and Prostate Cancer in Africa) Conference. Namibia, ZA.
- 2013. Using eHealth for cancer care delivery at a distance. Conference. AORTIC. Durban, ZA.
- 2013. Increased expression of Cadherin-11 in Bone-derived 786-O Renal Cell Carcinoma Cells. Invited. International Society of Limb Salvage, IT.
- 2013. Postradiation Osteosarcoma of the Pelvis. Invited. International Society of Limb Salvage, IT.
- 2013. Total humerus endoprosthetic replacement following resection of malignant bone tumors. Conference. Western Orthopaedic Association. Lake Tahoe, US.
- 2011. Simultaneous intramedullary nailing of skeletal metastases. Invited. Southern Orthopaedic Association Annual Meeting. Big Island, US.
- 2011. Presidential Guest Speaker: Orbital Orthopaedics: Reflections on Musculoskeletal Health and Space Exploration. Invited. American Orthopaedic Association, Annual Meeting. Boston, US.
- 2010. Keynote Address: Working for a Healthier World. Invited. Ronald McDonald House Scholars Annual Gala. Los Angeles, US.
- 2009. Keynote Address: Musculoskeletal Aspects of Astronaut Training and Space Flight. Invited. University of California, San Francisco (UCSF), 2nd International Conference, Advances in Orthopaedic Osseointegration. San Francisco, US.
- 2007. The Role of Metastasis-Associated Protein1 (MTA1) in Prostate Cancer Bone Metastases. Invited. Skeletal Complications of Malignancy V (Joint Symposium of The Paget Foundation and The Univ. of Michigan Medical School). Philadelphia, US.
- 2006. Stromal-epithelial crosstalk in prostate cancer bone metastasis. Conference. Podium presentation, 6th International Meeting of Cancer Induced Bone Disease. San Antonio, US.
- 2006. Cell-cell contact regulated genes and pathways in prostate bone metastasis formation. Conference. Podium presentation, 11th International Congress of Metastasis Research Society. Tokushima, JP.
- 2006. Estrogen regulated metastasis-associated genes in breast cancer metastasis to bone. Invited. 11th International Congress of Metastasis Research Society. Tokushima, JP.
- 2006. The Astronaut training experience at NASA. Invited. Annual meeting of the Centre for Australian Space Education and the Australian Science Teachers Association. Adelaide, AU.
- 2005. Physical contact between prostate cancer cells and osteoblasts regulated genes associated with tumor metastasis and osteogenesis. Invited. Podium presentation 2005 Orthopaedics Research Society 51st Annual Meeting. Washington, US.
- 2004. Cell to cell contact regulated genes in prostate cancer bone metastases. Invited. 2004 American Association for Cancer Research 95th Annual Meeting. Orlando, US.
- 2003. Both cell-cell contact and soluble factors mediate early events in the formation skeletal metastasis. Invited. 4th International Conference in Cancer Induced Bone Diseases, Paget Foundation. San Antonio, US.
- 2003. Contact induced gene regulation in co-cultures of metastastic cancer cells and bone cells using a novel in vitro system. Invited. Connective Tissue Society, 9th Annual Meeting. Barcelona, ES.
- 2003. Quantifying the role of cell-cell contact for establishing bone metastasis using a novel co-culture system. Invited. American Association for Cancer Research, 94th Annual Meeting. Washington, US.
- 1998. Long term anabolic response of bone cells to mechanical loading in vitro. Invited. 1998 2nd Joint meeting of the American Society of Bone and Mineral Research-International Bone and Mineral Society. San Francisco, US.
- 1990. Endothelial cell structure resulting from fluid shear stress. Invited. Frist World Congress of Biomechanics, UCSD. La Jolla, US.
Formal Peers
- 2023. Space Medicine and Orbital Orthopedics. Visiting. Durham, NC, US.
- 2022. BIGH3 Promotes Bone Destruction in RCC Bone Metastasis Progression. Visiting. Kansas City, KS, US.
- 2022. Orthopaedics and Orbits. Visiting. Kansas City, KS, US.
- 2022. Opening Keynote Speaker. Visiting. Winthrop, WA, US.
- 2022. Musculoskeletal Oncology Update. Visiting. Austin, TX, US.
- 2022. Musculoskeletal Oncology Update. Invited. Austin, TX, US.
- 2021. Orbits, Orthopaedics, Operating Rooms, and Oncology. Visiting. Baltimore, MD, US.
- 2020. Keynote Speaker: Explore, Find Answers, and Do More. Invited. Virtual Presentation, US.
- 2020. Keynote Speaker: Orbits & Operating Rooms. Visiting. Los Angeles (virtual presentation), CA, US.
- 2020. Keynote Speaker: Be Well, Do Good, and Contribute to the Benefit of All. Visiting. Boston (virtual presentation), MA, US.
- 2020. The relevance of race, diversity, and inclusion in challenging times: Observations from orbit…. Invited. Boston, MA, US.
- 2020. Courageous Leadership. Invited. Naples, FL, US.
- 2019. Keynote Address: From HST '94 to ISS. Visiting. Boston, MA, US.
- 2019. Keynote Address: Renal Cell Bone Metastasis: New Insights into Pathologic Mechanism. Visiting. Phoenix, AZ, US.
- 2017. Renal cell bone metastasis. Visiting. New Orleans, LA, US.
- 2017. Keynote Address, Leadership in Education. Invited. Columbia, SC, US.
- 2017. Keynote Address, Conversation with Hidden Figures. Invited. Houston, TX, US.
- 2017. A brief history of African Americans at NASA. Visiting. San Jose, CA, US.
- 2017. Diversity in Space Exploration. Visiting. Bentonville, AR, US.
- 2016. Keynote Address: Musculoskeletal health in space flight. Visiting. Birmingham, AL, US.
- 2016. Keynote Address: The role of the bone microenvironment in bone metastasis formation. Visiting. Seattle, WA, US.
- 2016. Keynote Address/Fellow's Orientation Day. Invited. Washington, DC, US.
- 2016. Nontraditional Postgraduate Opportunities. Invited. Chicago, IL, US.
- 2016. Identification of bone derived factors in metastatic renal cell carcinoma. Visiting. Duarte, CA, US.
- 2016. Panelist. Invited. Texarkana, TX, US.
- 2015. Orthopaedics in Orbit: The Final Frontier for Orthopaedics. Invited. San Francisco, CA, US.
- 2015. e-Health Tools for Use by Cancer Patients and Care Givers. Invited. Houston, TX, US.
- 2014. Three dimensional (3D) culture of prostate and renal cell bone metastasis. Visiting. Springfield, IL, US.
- 2014. The Bone Metastatic Potential of 786-0 Renal Cell Carcinoma Cells is Increased by Cadherin 11 Expression and Growth in 3D Culture. Invited. Springfield, IL, US.
- 2014. Challenges and Opportunities for the delivery of Cancer Care using Teleoncology. Visiting. Springfield, IL, US.
- 2014. Orthopaedics and Astronauts: An Evolving Story. Visiting. Springfield, IL, US.
- 2014. Metastatic bone disease in renal cell carcinoma. Visiting. Springfield, IL, US.
- 2013. Five Must Knows To Get Successful VC Funding. Invited. Houston, TX, US.
- 2013. Opening Address: The use of telemedicine and telesurgery in cancer care. Invited. Houston, TX, US.
- 2013. Opening Address: Overview of the Telehealth Research Institute. Invited. Houston, TX, US.
- 2013. Keynote Address: Healthcare equity: how far have we come?. Visiting. Milwaukee, WI, US.
- 2012. Keynote Address: The Value of Education. Visiting. Blue Bell, PA, US.
- 2012. Keynote Address: Telemedicine for improving access to specialized health care. Invited. Bethesda, MD, US.
- 2012. Get out of your comfort zone. Visiting. Denmark, SC, US.
- 2012. Keynote Address: Malignant tumor of bone. Invited. Brisbane, AU.
- 2012. Chairman's Panel Featured Speaker: Global Warming: Fact or Fiction. Invited. Heron Island, Queensland, AU.
- 2012. Ethnic Disparities in Cancer Care. Visiting. Columbia, SC, US.
- 2012. Grand Rounds Medical University of South Carolina Department of Orthopedic Surgey: Prostate cancer bone metastasis: gene expression and molecular pathways. Invited. Charleston, SC, US.
- 2012. Grand Rounds University of Tennessee: Surgical Management of Metastatic Bone Disease. Invited. Chattanooga, TN, US.
- 2012. Keynote Address: Robotics and Space Exploration. Visiting. College, MD, US.
- 2012. Keynote Address: Ethnicity as prognostic factor among patients with sarcoma. Visiting. Durham, NC, US.
- 2011. Keynote Lecture - Teamwork in Cancer Care. Invited. Chicago, IL, US.
- 2011. Musculoskeletal Health in Astronauts. Visiting. New Haven, CT, US.
- 2011. Keynote Address - Aiming high and achieving your goals. Invited. New Orleans, LA, US.
- 2011. Grand Rounds - Harvard Combined Orthopaedic Surgery: Musculoskeletal Health in Astronaut. Invited. Boston, MA, US.
- 2011. Don't Be Afraid. Visiting. Tallahassee, FL, US.
- 2011. Telemedicine and Space Exploration. Visiting. Worcester, MA, US.
- 2011. Is space exploration worth the risk?. Visiting. Washington, DC, US.
- 2011. Grand Rounds: Bone Mineral Changes during long duration space flight. Invited. New York, NY, US.
- 2010. Space Exploration: what does the future hold?. Visiting. Orangeburg, SC, US.
- 2008. Orthopedic Surgery Grand Rounds: Musculoskeletal Health in Spaceflight. Invited. Charlottesville, VA, US.
- 2008. Orthopedic Surgery Grand Rounds: Reconstruction of the pelvis after resection of tumors about the acetabulum. Invited. Detroit, MI, US.
- 2008. Leadership and Education: The best of times and the worst of times. Visiting. Blue Bell, PA, US.
- 2008. Metastatic bone disease in prostate cancer. Visiting. Orlando, FL, US.
- 2008. Keynote Speaker. Invited. Honolulu, HI, US.
- 2007. Impacts, pitfalls, and challenges of leadership in health care. Visiting. Baltimore, MD, US.
- 2007. NASA and the Future of Space Exploration. Invited. Chicago, IL, US.
- 2007. A tribute to NASA African American Astronauts: Past and Present. Invited. Berrien Springs, MI, US.
- 2006. The Exploration Vision for NASA. Invited. College Park, MD, US.
- 2006. Perspectives on Space Exploration. Invited. Adelaide, AU.
- 2006. From Harvard to NASA: An Alumni Perspective on Space, Medicine, and Astronauts. Visiting. Boston, MA, US.
- 2004. Heterotypic contact between osteoblasts and PC3 cells regulates bone metastasis formation. Invited. Newark, DE, US.
- 2001. Effects of physical forces on cultured cells. Visiting. San Diego, CA, US.
- 1999. Effects of pulsatile shear stress on osteoblast in vitro. Visiting. Berkeley, CA, US.
- 1998. The effects of mechanical forces on osteoblasts in vitro. Visiting. Berkeley, CA, US.
- 1997. Parallel Plate flow chamber for pulsatile flow fields. Visiting. Berkeley, CA, US.
- 1996. Mechanics of endothelial cells. Invited, CA, US.
Grant & Contract Support
| Date: | 2022 - 2023 |
| Title: | Mapping Cellular Interplay of the Osteocyte Connectome in Metastatic Renal Cell Carcinoma Interplay of the Osteocyte Connectome in Metastatic Renal Cell |
| Funding Source: | UT School of Dentistry Research Accelerator Grant |
| Role: | Co-PI |
| Date: | 2022 - 2026 |
| Title: | Next Generation Rat Models of ER+ Breast Cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | R01 CA271498-01 |
| Date: | 2020 - 2022 |
| Title: | Targeting the osteogenic niche for preventing kidney cancer bone metastasis progression |
| Funding Source: | Department of Defense (DOD) |
| Role: | PI |
| ID: | FP00009364 |
| Date: | 2020 |
| Title: | Establishment and validation of bone metastasis PDX/PDO models for better translational research |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2020 |
| Title: | Renal cell carcinoma, osteocyte death and bone osteolysis: engineering approaches to conquering bone metastasis |
| Funding Source: | NIH/NIBIB |
| Role: | PI |
| ID: | GRANT13010739 |
| Date: | 2019 - 2020 |
| Title: | Bridge Funding: Improved therapy for kidney cancer bone metastasis based on targeting osteoblast inhibition |
| Funding Source: | MD Anderson Cancer Center |
| Role: | PI |
| ID: | KC170029 |
| Date: | 2017 - 2020 |
| Title: | Study of BIGH3 inhibition of bone formation as a novel mechanism for osteolysis in treatment resistant kidney cancer bone metastasis |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Principal Investigator-MDACC |
| ID: | RP170414 |
| Date: | 2016 - 2017 |
| Title: | Knowledge Gap: BIGH3 inhibition of osteoblasts is a novel mechanism of osteolysis in kidney cancer bone metastasis |
| Funding Source: | The University of Texas, MD Anderson Cancer Center |
| Role: | PI |
| Date: | 2016 - 2020 |
| Title: | Adipose and bone marrow stroma as determinants of metastatic cancer progression |
| Funding Source: | Department of Defense (DOD) |
| Role: | Co-PI |
| ID: | PC160254 |
| Date: | 2016 - 2019 |
| Title: | BIGH3 inhibition of osteoblasts is a novel mechanism of osteolysis in kidney cancer bone metastasis |
| Funding Source: | Orthopaedic Research and Education Foundation |
| Role: | PI |
| Date: | 2016 - 2019 |
| Title: | Multidisciplinary Research Grant - Department of Translational Research |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | Co-PI |
| Date: | 2015 - 2019 |
| Title: | Using telemonitoring to optimize the mobility of cancer survivors with skeletal metastases after surgery to preserve limb function |
| Funding Source: | The University of Texas MD Anderson Cancer Center Cancer Survivorship Research RFA |
| Role: | PI |
| Date: | 2014 - 2016 |
| Title: | de novo Therapy resistance from prostate cancer metastasis-induced bone formation |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | Principal Investigator-MDACC |
| Date: | 2014 |
| Title: | R. Lee Clark Fellowship Grant Proposal |
| Funding Source: | The University of Texas M.D. Anderson Cancer Center |
| Role: | Principal Investigator-MDACC |
| Date: | 2012 |
| Title: | NO TITLE PROVIDED |
| Funding Source: | John S. Dunn Foundation Collaborative Research Award |
| Role: | PI |
| Date: | 2011 - 2014 |
| Title: | NO TITLE PROVIDED |
| Funding Source: | ATT Telesurgery Grant |
| Role: | Co-I |
| Date: | 2008 - 2011 |
| Title: | Robert Wood Johnson Foundation |
| Funding Source: | Robert Wood Johnson Foundation |
| Role: | PI |
| Date: | 2005 - 2010 |
| Title: | Nanotechnology Strategies for growth of bones and teeth |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | R01-DE015920-01A1 |
| Date: | 2004 - 2006 |
| Title: | SPORE in prostate cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2003 - 2005 |
| Title: | Robert Wood Johnson Foundation |
| Funding Source: | Robert Wood Johnson Foundation |
| Role: | PI |
| Date: | 2003 - 2004 |
| Title: | Estrogen and selective receptor modulators (SERMS) in breast cancer metastases to bone |
| Funding Source: | Avon Foundation |
| Role: | Co-I |
| Date: | 2002 - 2003 |
| Title: | The use of mechanical forces to influence stem cell growth and development for the production of bone substitutes |
| Funding Source: | Orthopedic Research and Education Foundation, Zimmer Career Development Award |
| Role: | PI |
| Date: | 2002 - 2003 |
| Title: | Role of cell contact in prostate skeletal metastasis |
| Funding Source: | Robert H. Lurie Comprehensive Cancer Center, SPORE in prostate cancer |
| Role: | PI |
| Date: | 2001 - 2002 |
| Title: | Stem cell growth and Differentiation is influenced by mechanical forces |
| Funding Source: | Children's Research Foundation, Children's Memorial Hospital |
| Role: | PI |
| Date: | 1997 - 1999 |
| Title: | NO TITLE PROVIDED |
| Funding Source: | Merck/UNCF Biomedical Foundation |
| Role: | PI |
| Date: | 1985 |
| Title: | In Vivo study of the use of antibiotic loaded biodegradable matrices in the treatment of osteomyelitis |
| Funding Source: | MIT Undergraduate Research Grant |
| Role: | Co-I |
| Title: | Renal Cell Carcinoma Bone Metastasis |
| Funding Source: | UAE Charitable Donation |
| Role: | PI |
| Title: | Inhibition of osteoblast differentiation by BIGH3 in osteolytic renal cell carcinoma bone metastasis |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Principal Investigator-MDACC |
| Title: | Osteocyte Apoptosis Induced by Colonizing Tumor Cells Precedes Osteolysis during Renal Cell Carcinoma Bone Metastasis Progression |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator-MDACC |
| ID: | FP00009094 |
| Title: | Targeting Treatment-Refractory Osteolysis in ccRCC Metastasis Associated with BIGH3-Induced Bone Anabolic Failure |
| Funding Source: | Department of Defense (DOD) |
| Role: | PI |
| Title: | Osteolytic bone metastasis in treatment resistant kidney cancer |
| Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
| Role: | PI |
| ID: | CA160089 |
| Title: | Improved therapy for kidney cancer bone metastasis based on targeting osteoblast inhibition |
| Funding Source: | Department of Defense (DOD) |
| Role: | PI |
| ID: | KC170029 |
| Title: | Adipose and marrow stroma foster prostate cancer bone metastasis |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| ID: | RP180219 |
| Title: | Improving breast cancer patient surveillance and treatment in Ethiopia using a smartphone platform |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Principal Investigator-MDACC |
| Title: | An anabolic strategy for targeted therapy for kidney cancer bone metastasis |
| Funding Source: | Department of Defense (DOD) |
| Role: | Principal Investigator-MDACC |
| ID: | FP0000665 |
| Title: | Treating osteolysis in renal cell carcinoma bone metastasis by targeting osteoblast inhibition |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | FP00003605 |
Selected Publications
Peer-Reviewed Articles
- Han Y, Sarkar H, Xu Z, Lopez-Darwin S, Wei Y, Hang X, Liu F, Tran K, Wang W, Miller JM, DeCoste CJ, Blohm DS, Satcher RL, Zhang XH, Kang Y. Tumors hijack macrophages for iron supply to promote bone metastasis and anemia. Cell 188(22):6335-6354.e26, 2025. e-Pub 2025. PMID: 40907490.
- Liu, F, Ding, Y, Xu, Z, Hao, X, Pan, T, Miles, G, Wang, S, Wu, YH, Liu, J, Bado, I, Zhang, W, Wu, L, Gao, Y, Yu, L, Edwards, DG, Chan, HL, Aguirre, S, Dieffenbach, MW, Chen, E, Shen, Y, Hoffman, D, Becerra-Dominguez, L, Rivas, C, Chen, X, Wang, H, Gugala, Z, Satcher, R, Zhang, XH. Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization. Cell Genomics 5(7), 2025. e-Pub 2025.
- Liu F, Ding Y, Xu Z, Hao X, Pan T, Miles G, Wang S, Wu YH, Liu J, Bado IL, Zhang W, Wu L, Gao Y, Yu L, Edwards DG, Chan HL, Aguirre S, Dieffenbach MW, Chen E, Shen Y, Hoffman D, Becerra Dominguez L, Rivas CH, Chen X, Wang H, Gugala Z, Satcher RL, Zhang XH. Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization. Cell Genom 5(7):100888, 2025. e-Pub 2025. PMID: 40412393.
- Han Y, Sarkar H, Xu Z, Lopez-Darwin S, Wei Y, Hang X, Liu F, Tran K, Wang W, Miller JM, DeCoste CJ, Blohm D, Satcher RL, Zhang XH, Kang Y. Niche Macrophages Recycle Iron to Tumor Cells and Foster Erythroblast Mimicry to Promote Bone Metastasis and Anemia. bioRxiv, 2025. e-Pub 2025. PMID: 41031013.
- Biermann JS, Hirbe A, Ahlawat S, Bernthal NM, Binitie O, Boles S, Brigman B, Callan AK, Cipriano C, Cranmer LD, Davis J, Donnelly E, Ferguson M, Graham A, Groundland J, Hess M, Hiniker SM, Hoover-Regan ML, Hornick JL, Jonard B, Kuechle JB, Lindskog D, Mayerson JL, McGarry SV, Morris CD, Olson D, Rose PS, Santana VM, Satcher RL, Schwartz H, Shulman RM, Thorpe SW, Wilky BA, Wustrack RL, Yoon J, Hang LE, Jones F, Sansone N, Lyons M. Bone Cancer, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology. J Natl Compr Canc Netw 23(4), 2025. e-Pub 2025. PMID: 40203873.
- Bishop, AJ, Mitra, D, Farooqi, AS, Swanson, DM, Hempel, C, Willis, T, Pearlnath, C, Wang, W, Ratan, R, Somaiah, N, Benjamin, RS, Torres, KE, Hunt, KK, Scally, CP, Keung, EZ, Satcher, R, Bird, JE, Lin, PP, Moon, BS, Lewis, VO, Roland, CL, Guadagnolo, BA. Moderately hypofractionated, preoperative radiotherapy in patients with soft tissue sarcomas (HYPORT-STS). Cancer 131(1), 2025. e-Pub 2025. PMID: 39192597.
- McChesney GR, Al Farii H, Singleterry S, Lewis VO, Moon BS, Satcher RL, Bird JE, Lin PP. Can Periprosthetic Joint Infection of Tumor Prostheses Be Controlled With Debridement, Antibiotics, and Implant Retention?. Clin Orthop Relat Res 483(1):49-58, 2025. e-Pub 2025. PMID: 38991232.
- Pan, T, Liu, F, Hao, X, Wang, S, Wasi, M, Song, J, Lewis, VO, Lin, PP, Moon, BS, Bird, JE, Panaretakis, T, Lin, S, Wu, D, Farach-Carson, MC, Wang, L, Zhang, N, An, Z, Zhang, XH, Satcher, R. BIGH3 mediates apoptosis and gap junction failure in osteocytes during renal cell carcinoma bone metastasis progression. Cancer Letters 596, 2024. e-Pub 2024. PMID: 38849015.
- Hirase, T, Rowan, C, Jacob, T, Vemu, SM, Aflatooni, JO, Patel, SS, Satcher, R, Lin, PP, Moon, BS, Lewis, VO, Marco, RA, Bird, JE. Percutaneous Cementation for Improvement of Pain and Function for Osteolytic Pelvic Metastasis. Journal of the American Academy of Orthopaedic Surgeons 32(14):e726-e736, 2024. e-Pub 2024. PMID: 38709827.
- Kim, M, Maldonado, JA, Pandey, P, El Alam, MB, Kouzy, R, Christopherson, KM, Minsky, B, Nugyen, QN, Grosshans, DR, Lin, LL, Mitchell, MP, Klopp, AH, Lee, PP, Bird, JE, Satcher, R, Lewis, VO, Lin, PP, Tang, C, Koong, A, Moon, BS, Colbert, LE. Single-fraction radiation retreatment for bone metastases. BMJ Supportive and Palliative Care 14(e2), 2024. e-Pub 2024. PMID: 38843933.
- Paindelli, C, Parietti, V, Barrios, S, Shepherd, P, Pan, T, Wang, W, Satcher, R, Logothetis, CJ, Navone, NM, Campbell, M, Mikos, AG, Dondossola, E. Bone mimetic environments support engineering, propagation, and analysis of therapeutic response of patient-derived cells, ex vivo and in vivo. Acta Biomaterialia 178:83-92, 2024. e-Pub 2024. PMID: 38387748.
- Hirase, T, McChesney, GR, Garvin, L, Tappa, KK, Satcher, R, Mericli, AF, Rhines, LD, Bird, JE. Advances in Virtual Cutting Guide and Stereotactic Navigation for Complex Tumor Resections of the Sacrum and Pelvis. Bioengineering 10(12), 2023. e-Pub 2023. PMID: 38135933.
- Johnson, JD, Satcher, R, Feng, L, Lewis, VO, Moon, BS, Bird, JE, Lin, PP. What Is the Prosthetic Survival After Resection and Intercalary Endoprosthetic Reconstruction for Diaphyseal Bone Metastases of the Humerus and Femur?. Clinical orthopaedics and related research 481(11):2200-2210, 2023. e-Pub 2023. PMID: 37185204.
- Witt, RG, Voss, RK, Chiang, YJ, Nguyen, S, Scally, CP, Lin, PP, Torres, KE, Moon, BS, Satcher, R, Hunt, KK, Bird, JE, Feig, BW, Lewis, VO, Roland, CL, Keung, EZ. ASO Visual Abstract. Annals of surgical oncology 30(6):3679-3680, 2023. e-Pub 2023. PMID: 36826618.
- Witt RG, Voss RK, Chiang YJ, Nguyen S, Scally CP, Lin PP, Torres KE, Moon BS, Satcher RL, Hunt KK, Bird JE, Feig BW, Lewis VO, Roland CL, Keung EZ. Practice Pattern Variability in the Management of Regional Lymph Node Metastasis in Extremity and Trunk Soft Tissue Sarcoma: A Survey of the Society of Surgical Oncology and Musculoskeletal Tumor Society Membership. Ann Surg Oncol 30(6):3668-3676, 2023. e-Pub 2023. PMID: 36723723.
- Zhang W, Xu Z, Hao X, He T, Li J, Shen Y, Liu K, Gao Y, Liu J, Edwards DG, Muscarella AM, Wu L, Yu L, Xu L, Chen X, Wu YH, Bado IL, Ding Y, Aguirre S, Wang H, Gugala Z, Satcher RL, Wong STC, Zhang XH. Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells. Cancer Discov 13(2):474-495, 2023. e-Pub 2023. PMID: 36287038.
- Guadagnolo BA, Bassett RL, Mitra D, Farooqi A, Hempel C, Dorber C, Willis T, Wang WL, Ratan R, Somaiah N, Benjamin RS, Torres KE, Hunt KK, Scally CP, Keung EZ, Satcher RL, Bird JE, Lin PP, Moon BS, Lewis VO, Roland CL, Bishop AJ. Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open-label, single-arm, phase 2 trial. Lancet Oncol 23(12):1547-1557, 2022. e-Pub 2022. PMID: 36343656.
- Satcher RL. CORR Insights®: What Factors Are Associated with Local Metastatic Lesion Progression after Intramedullary Nail Stabilization?. Clin Orthop Relat Res 480(5):946-948, 2022. e-Pub 2022. PMID: 35302531.
- Pan T, Lin SC, Lee YC, Yu G, Song JH, Pan J, Titus M, Satcher RL, Panaretakis T, Logothetis C, Yu-Lee LY, Lin SH. Statins reduce castration-induced bone marrow adiposity and prostate cancer progression in bone. Oncogene 40(27):4592-4603, 2021. e-Pub 2021. PMID: 34127814.
- Liu J, Fan Z, El Beaino M, Lewis VO, Moon BS, Satcher RL, Bird JE, Frink SJ, Lin PP. Surgical drainage after limb salvage surgery and endoprosthetic reconstruction: is 30 mL/day critical?. J Orthop Surg Res 16(1):137, 2021. e-Pub 2021. PMID: 33588915.
- Kumar R, Lefkowitz RA, Agaram NP, Amini B, Satcher RL, Wang WL. Spindle Cell Lipoma Revisited: Common and Unusual Magnetic Resonance Imaging Findings in 54 Patients With New Observations. J Comput Assist Tomogr 45(4):564-570, 2021. e-Pub 2021. PMID: 34270478.
- Callan AK, Singleterry S, Czerniak BA, Selber JC, Satcher RL. Total tibial allograft reconstruction for adamantinoma: a case report with 2 year follow up. JBJS Case Connect 10(4):e20.00046, 2020. e-Pub 2020. PMID: 33449546.
- Pan T, Martinez M, Hubka KM, Song JH, Lin SC, Yu G, Lee YC, Gallick GE, Tu SM, Harrington DA, Farach-Carson MC, Lin SH, Satcher RL. Cabozantinib reverses renal cell carcinoma mediated osteoblast inhibition in three-dimensional co-culture in vitro and reduces bone osteolysis in vivo. Mol Cancer Ther 19(6):1266-1278, 2020. e-Pub 2020. PMID: 32220969.
- Bishop AJ, Bird JE, Conley AP, Roland CL, Moon BS, Satcher RL, Livingston JA, Patel S, Wang WL, Lazar AJ, Lewis VO, Lin PP, Guadagnolo BA. Extraskeletal Myxoid Chondrosarcomas: Combined Modality Therapy With Both Radiation and Surgery Improves Local Control. Am J Clin Oncol 42(10):744-748, 2019. e-Pub 2019. PMID: 31436747.
- Elhammali A, Milgrom SA, Amini B, Gunther JR, Yoder A, Ludmir EB, Moon B, Weber DM, Thomas SK, Garg N, Manasanch EE, Patel KK, Orlowski RZ, Lee HC, Bird JE, Satcher R, Lin P, Pinnix CC, Dabaja BS. Postoperative Radiotherapy for Multiple Myeloma of Long Bones: Should the Entire Rod Be Treated?. Clin Lymphoma Myeloma Leuk 19(8):e465-e469, 2019. e-Pub 2019. PMID: 31133526.
- Wallace MT, Lin PP, Bird JE, Moon BS, Satcher RL, Lewis VO. The Accuracy and Clinical Utility of Intraoperative Frozen Section Analysis in Open Biopsy of Bone. J Am Acad Orthop Surg 27(11):410-417, 2019. e-Pub 2019. PMID: 30379758.
- Chafey DH, Lewis VO, Satcher RL, Moon BS, Lin PP. Is a Cephalomedullary Nail Durable Treatment for Patients With Metastatic Peritrochanteric Disease?. Clin Orthop Relat Res 476(12):2392-2401, 2018. e-Pub 2018. PMID: 30299285.
- Pan T, Lin SC, Yu KJ, Yu G, Song JH, Lewis VO, Bird JE, Moon BS, Lin PP, Tannir NM, Jonash E, Wood CG, Gallick GE, Yu-Lee LY, Lin SH, Satcher RL. BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation. Neoplasia 20(1):32-43, 2018. e-Pub 2018.
- Yu KJ, Li JK, Lee YC, Yu G, Lin SC, Pan T, Satcher RL, Titus MA, Yu-Lee LY, Weng WH, Gallick GE, Lin SH. Cabozantinib-induced osteoblast secretome promotes survival and migration of metastatic prostate cancer cells in bone. Oncotarget 8(43):74987-75006, 2017. e-Pub 2017. PMID: 29088840.
- Bilen MA, Pan T, Lee YC, Lin SC, Yu G, Pan J, Hawke D, Pan BF, Vykoukal J, Gray K, Satcher RL, Gallick GE, Yu-Lee LY, Lin SH. Proteomics Profiling of Exosomes from Primary Mouse Osteoblasts under Proliferation versus Mineralization Conditions and Characterization of Their Uptake into Prostate Cancer Cells. J Proteome Res 16(8):2709-2728, 2017. e-Pub 2017. PMID: 28675788.
- Farach-Carson CM, Lin SH, Nalty T, Satcher RL. Sex Differences and Bone Metastases of Breast, Lung, and Prostate Cancers: Do Bone Homing Cancers Favor Feminized Bone Marrow?. Frontiers in Oncology 7(163), 2017. e-Pub 2017.
- Satcher RL. Postpartum treatment of metastatic recurrent giant cell tumor of the capitate bone of the wrist. The American Journal of Orthopedics 46(4):E269-275, 2017. e-Pub 2017.
- Kalra S, Verma J, Atkinson BJ, Matin SF, Wood CG, Karam JA, Lin SH, Satcher RL, Tamboli P, Sircar K, Rao P, Corn PG, Tannir NM, Jonasch E. Outcomes of Patients With Metastatic Renal Cell Carcinoma and Bone Metastases in the Targeted Therapy Era. Clin Genitourin Cancer 15(3):363-370, 2017. e-Pub 2017. PMID: 28216278.
- Moon BS, Dunbar DJ, Lin PP, Satcher RL, Bird JE, Lewis VO. Is It Appropriate to Treat Sarcoma Metastases With Intramedullary Nailing?. Clin Orthop Relat Res 475(1):212-217, 2017. e-Pub 2017. PMID: 27804017.
- Etchebehere M, Lin PP, Bird JE, Satcher RL, Moon BS, Yu J, Li L, Lewis VO. Patellar Resurfacing: Does It Affect Outcomes of Distal Femoral Replacement After Distal Femoral Resection?. J Bone Joint Surg Am 98(7):544-51, 2016. e-Pub 2016. PMID: 27053582.
- Kotwal S, Moon B, Lin P, Satcher R, Lewis V. Total Humeral Endoprosthetic Replacement following Excision of Malignant Bone Tumors. Sarcoma 2016:6318060, 2016. e-Pub 2016. PMID: 27042158.
- Bird JE, Morse LJ, Feng L, Wang WL, Lin PP, Moon BS, Lazar AJ, Satcher RL, Madewell JE, Lewis VO. Non-Radiographic Risk Factors Differentiating Atypical Lipomatous Tumors from Lipomas. Front Oncol 6:197, 2016. e-Pub 2016. PMID: 27713864.
- Arteau A, Lewis VO, Moon BS, Satcher RL, Bird JE, Lin PP. Tibial Growth Disturbance Following Distal Femoral Resection and Expandable Endoprosthetic Reconstruction. J Bone Joint Surg Am 97(22):e72, 2015. e-Pub 2015. PMID: 26582624.
- Lee YC, Lin SC, Yu G, Cheng CJ, Liu B, Liu HC, Hawke DH, Parikh NU, Varkaris A, Corn P, Logothetis C, Satcher RL, Yu-Lee LY, Gallick GE, Lin SH. Identification of Bone-Derived Factors Conferring De Novo Therapeutic Resistance in Metastatic Prostate Cancer. Cancer Res 75(22):4949-59, 2015. e-Pub 2015. PMID: 26530902.
- Satcher RL, Pan T, Bilen MA, Li X, Lee YC, Ortiz A, Kowalczyk AP, Yu-Lee LY, Lin SH. Cadherin-11 endocytosis through binding to clathrin promotes cadherin-11-mediated migration in prostate cancer cells. J Cell Sci. e-Pub 2015. PMID: 26519476.
- Pan T, Fong EL, Martinez M, Harrington DA, Lin SH, Farach-Carson MC, Satcher RL. Three-dimensional (3D) culture of bone-derived human 786-O renal cell carcinoma retains relevant clinical characteristics of bone metastases. Cancer Lett. e-Pub 2015. PMID: 26004343.
- Moon B, Lin P, Satcher R, Bird J, Lewis V. Intramedullary nailing of femoral diaphyseal metastases: is it necessary to protect the femoral neck?. Clin Orthop Relat Res 473(4):1499-502, 2015. e-Pub 2015. PMID: 25424158.
- Krygier JE, Lewis VO, Cannon CP, Satcher RL, Moon BS, Lin PP. Operative Management of Metastatic Melanoma in Bone May Require En Bloc Resection of Disease. Clin Orthop Relat Res 472(10):3196-203, 2014. e-Pub 2014. PMID: 24989125.
- Takeuchi A, Lewis VO, Satcher RL, Moon BS, Lin PP. What Are the Factors That Affect Survival and Relapse After Local Recurrence of Osteosarcoma. Clin Orthop Relat Res 472(10):3188-95, 2014. e-Pub 2014. PMID: 24980644.
- Satcher RL, Pan T, Cheng C, Lee Y, Lin S, Yu G, Li X, Hoang A, Tamboli P, Jonasch E, Gallick G, Lin S. Cadherin-11 in Renal Cell Carcinoma Bone Metastasis. PLOS ONE 9(2):1-10. e-Pub 2014.
- Satcher RL, Lin PP, Huran N, Fen L, Moon BS, Lewis VO. The benefit of surgical management of colorectal carcinoma bone metastases. Journal of Solid Tumors 3(6):27-37, 2013. e-Pub 2013.
- Lee YC, Bilen MA, Yu G, Lin SC, Huang CF, Ortiz A, Cho H, Song JH, Satcher RL, Kuang J, Gallick GE, Yu-Lee LY, Huang W, Lin SH. Inhibition of Cell Adhesion by an Anti-cadherin 11 Antibody Prevents Bone Metastasis. Mol Cancer Res. e-Pub 2013. PMID: 23913163.
- Xing Z, Moon BS, Satcher RL, Lin PP, Lewis VO. A long femoral stem is not always required in hip arthroplasty for patients with proximal femur metastases. Clin Orthop Relat Res 471(5):1622-7, 2013. e-Pub 2013. PMID: 23361930.
- Satcher RL, Bamidele O, Lin PP, Lin SH, Moon BS, Hernandez M, Lewis VO, Chilton J. Racial disparities in survival outcomes of prostate cancer patients after surgery for bone metastases. Journal of Cancer Therapy 4:27-36, 2013. e-Pub 2013.
- Satcher RL, Lin P, Harun N, Feng L, Moon BS, Lewis VO. Surgical management of appendicular skeletal metastases in thyroid carcinoma. Int J Surg Oncol 2012:417086, 2012. e-Pub 2012. PMID: 23304478.
- Lee YC, Cheng CJ, Bilen MA, Lu JF, Satcher RL, Yu-Lee LY, Gallick GE, Maity SN, Lin SH. BMP4 promotes prostate tumor growth in bone through osteogenesis. Cancer Res 71(15):5194-203, 2011. e-Pub 2011. PMID: 21670081.
- Moon B, Lin P, Satcher R, Lewis V. Simultaneous nailing of skeletal metastases: is the mortality really that high?. Clin Orthop Relat Res 469(8):2367-70, 2011. e-Pub 2011. PMID: 21328019.
- Kai L, Wang J, Ivanovic M, Chung YT, Laskin WB, Schulze-Hoepfner F, Mirochnik Y, Satcher RL, Levenson AS. Targeting prostate cancer angiogenesis through metastasis-associated protein 1 (MTA1). Prostate 71(3):268-80, 2011. e-Pub 2011. PMID: 20717904.
- Mata A, Geng Y, Henrikson KJ, Aparicio C, Stock SR, Satcher RL, Stupp SI. Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix. Biomaterials 31(23):6004-12, 2010. e-Pub 2010. PMID: 20472286.
- Zhang S, Wang J, Bilen MA, Lin SH, Stupp SI, Satcher RL. Modulation of prostate cancer cell gene expression by cell-to-cell contact with bone marrow stromal cells or osteoblasts. Clin Exp Metastasis 26(8):993-1004, 2009. e-Pub 2009. PMID: 19787436.
- Kai L, Wang J, Chung YT, Jerrett J, Laskin W, Huang CC, Satcher RL, Levenson AS. Metastasis-associated protein 1 as a potential biomarker and target for the management of prostate cancer bone metastases. The Journal Of Urology 179(4):390-390, 2008. e-Pub 2008.
- Levenson AS, Wang J, Chung Y, Romanchuk JJ, Laskin WB, Huang C, Satcher RL. The role of metastasis-associated protein 1 (MTA1) in prostate cancer bone metastases. Clinical & Experimental Metastasis 25:42-42, 2008. e-Pub 2008.
- Sargeant TD, Guler MO, Oppenheimer SM, Mata A, Satcher RL, Dunand DC, Stupp SI. Hybrid bone implants: self-assembly of peptide amphiphile nanofibers within porous titanium. Biomaterials 29(2):161-71, 2008. e-Pub 2008. PMID: 17936353.
- Levenson AS, Wang J, Chung YT, Romanchuk JJ, Satcher RL. Estrogen regulated metastasis-associated genes in breast cancer bone metastases. Clinical & Experimental Metastasis 24(4):283-284, 2007. e-Pub 2007.
- Wang J, Jarrett J, Huang CC, Satcher RL, Levenson AS. Identification of estrogen-responsive genes involved in breast cancer metastases to the bone. Clin Exp Metastasis 24(6):411-22, 2007. e-Pub 2007. PMID: 17593529.
- Wang J, Levenson AS, Satcher RL. Identification of a unique set of genes altered during cell-cell contact in an in vitro model of prostate cancer bone metastasis. Int J Mol Med 17(5):849-56, 2006. e-Pub 2006. PMID: 16596270.
- Levenson AS, Thurn KE, Simons LA, Veliceasa D, Jarrett J, Osipo C, Jordan VC, Volpert OV, Satcher RL, Gartenhaus RB. MCT-1 oncogene contributes to increased in vivo tumorigenicity of MCF7 cells by promotion of angiogenesis and inhibition of apoptosis. Cancer Res 65(23):10651-6, 2005. e-Pub 2005. PMID: 16322206.
- Levenson AS, Thurn TE, Veliceasa D, Jerrett J, Osipo C, Jordan V, Ov V, Satcher RL, Gartenhaus RB. Overexpression of MCTA oncogene contributes to increased tumurogenicity of MCF7 breast cancer cells. Cancer Research 65(23):10651 - 6, 2005. e-Pub 2005.
- Satcher RL, Dvorkin K, Levenson AS, Vandenbroek T, Stupp SI. Gene expression in cancer cells is influenced by contact with bone cells in a novel coculture system that models bone metastasis. Clin Orthop Relat Res(426):54-63, 2004. e-Pub 2004. PMID: 15346052.
- Garcia ND, Morasch MD, Sam AD, Satcher RL, Blum MG, Fullerton DA. Inferior vena cava thrombus removal using hypothermic circulatory arrest in two patients with osteosarcoma. Ann Vasc Surg 17(6):686-9, 2003. e-Pub 2003. PMID: 14738095.
- Satcher RL, Noss RS, Yingling CD, Ressler J, Ries M. The use of motor-evoked potentials to monitor sciatic nerve status during revision total hip arthroplasty. J Arthroplasty 18(3):329-32, 2003. e-Pub 2003. PMID: 12728425.
- Satcher RL, Levenson AS, Dvorkin K, Stupp SI. Quantifying the role of cell-cell contact for establishing bone metastasis using a novel co-culture system. Proceeding of the American Association for Cancer Research 44(55), 2003. e-Pub 2003.
- Satcher, RL, O'Donnell R, Johnston JO. Reconstruction of the pelvis following resection of malignant tumors about the acetabulum. Clinical Orthopaedics and Related Research 1(408), 2003. e-Pub 2003.
- Nauman EA, Satcher RL, Keaveny TM, Halloran BP, Bikle DD. Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE(2) but no change in mineralization. J Appl Physiol 90(5):1849-54, 2001. e-Pub 2001. PMID: 11299276.
- Allred DR, Carlton JM, Satcher RL, Long JA, Brown WC, Patterson PE, O'Connor RM, Stroup SE. The ves multigene family of B. bovis encodes components of rapid antigenic variation at the infected erythrocyte surface. Mol Cell 5(1):153-62, 2000. e-Pub 2000. PMID: 10678177.
- Satcher RL. African Americans and orthopaedic surgery. A resident's perspective. Clin Orthop Relat Res(362):114-6, 1999. e-Pub 1999. PMID: 10335289.
- Nauman EA, Risic KJ, Keaveny TM, |BSatcher RL. Quantitative assessment of steady and pulsatile flow fields in a parallel plate flow chamber. Ann Biomed Eng 27(2):194-9, 1999. e-Pub 1999. PMID: 10199696.
- Nauman EA, Chang WCW, Satcher RL, Keaveny TM. Microscale Engineering applications in bone adaption. Microscale Thermophysical Engineering 2:139-172, 1998. e-Pub 1998.
- Satcher R, Dewey CF, Hartwig JH. Mechanical remodeling of the endothelial surface and actin cytoskeleton induced by fluid flow. Microcirculation 4(4):439-53, 1997. e-Pub 1997. PMID: 9431512.
- Satcher RL, Dewey CF. Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton. Biophys J 71(1):109-18, 1996. e-Pub 1996. PMID: 8804594.
- Satcher RL, Dewey CF. Mechanical properties of actin cytoskeleton of endothelial cells. Annals of Biomedical Engineering 23(Supplement 1):s-26, 1995. e-Pub 1995.
- Laurencin CT, Gerhart T, Witschger P, Satcher R, Domb A, Rosenberg AE, Hanff P, Edsberg L, Hayes W, Langer R. Bioerodible polyanhydrides for antibiotic drug delivery: in vivo osteomyelitis treatment in a rat model system. J Orthop Res 11(2):256-62, 1993. e-Pub 1993. PMID: 8483038.
- Satcher RL, Bussolari SR, Gimbrone MA, Dewey CF. The distribution of fluid forces on model arterial endothelium using computational fluid dynamics. J Biomech Eng 114(3):309-16, 1992. e-Pub 1992. PMID: 1522724.
- Kemp AK, Singleterry S, Huynh TT, Lewis VO, Satcher RL. Treatment outcomes for atraumatic acute compartment syndrome in orthopaedic oncology patients. JBJS.
Invited Articles
- Flint JH, Conley AP, Rubin M, Feng L, Lin PP, Moon B, Bird J, Satcher RL, Lewis VO. Clear Cell Chondrosarcoma: Clinical Characteristics and Outcomes in 15 Patients. Sarcoma 2020(Article ID 2386191):1-6, 2020. e-Pub 2020.
- Biermann JS, Chow W, Reed DR, Lucas D, Adkins DR, Agulnik M, Benjamin RS, Brigman B, Budd GT, Curry WT, Didwania A, Fabbri N, Hornicek FJ, Kuechle JB, Lindskog D, Mayerson J, McGarry SV, Million L, Morris CD, Movva S, O'Donnell RJ, Randall RL, Rose P, Santana VM, Satcher RL, Schwartz H, Siegel HJ, Thornton K, Villalobos V, Bergman MA, Scavone JL. NCCN Guidelines Insights: Bone Cancer, Version 2.2017. J Natl Compr Canc Netw 15(2):155-167, 2017. e-Pub 2017. PMID: 28188186.
- Biermann JS, Adkins DR, Agulnik M, Benjamin RS, Brigman B, Butrynski JE, Cheong D, Chow W, Curry WT, Frassica DA, Frassica FJ, Hande KR, Hornicek FJ, Jones RL, Mayerson J, McGarry SV, McGrath B, Morris CD, O'Donnell RJ, Randall RL, Santana VM, Satcher RL, Siegel HJ, von Mehren M, Bergman MA, Sundar H. Bone cancer. J Natl Compr Canc Netw 11(6):688-723, 2013. e-Pub 2013. PMID: 23744868.
- Biermann JS, Adkins DR, Benjamin RS, Brigman B, Chow W, Conrad EU, Frassica DA, Frassica FJ, George S, Hande KR, Hornicek FJ, Letson GD, Mayerson J, McGarry SV, McGrath B, Morris CD, O'Donnell RJ, Randall RL, Santana VM, Satcher RL, Siegel HJ, Somaiah N, Yasko AW, Cancer Panel NCCNB. Bone cancer. J Natl Compr Canc Netw 8(6):688-712, 2010. e-Pub 2010. PMID: 20581300.
- Satcher R. An orthopaedic surgeon in space: an interview with Robert Satcher, MD, PhD. Interview by Tony Peregrin. Bull Am Coll Surg 95(4):11-5, 2010. e-Pub 2010. PMID: 21456425.
- Biermann JS, Adkins D, Benjamin R, Brigman B, Chow W, Conrad EU, Frassica D, Frassica FJ, George S, Healey JH, Heck R, Letson GD, Mayerson J, McGarry SV, O'Donnell RJ, Patt J, Randall RL, Santana V, Satcher RL, Schmidt RG, Siegel HJ, Wong MK, Yasko AW, Cancer Network NC. Bone cancer. J Natl Compr Canc Netw 5(4):420-37, 2007. e-Pub 2007. PMID: 17442233.
- Biermann JS, Baker LH, Benjamin R, Brigman B, Chow W, Conrad EU, Frassica D, Frassica FJ, George S, Healey JH, Heck R, Letson GD, Mayerson J, Neff J, O'Donnell RJ, Randall RL, Santana V, Satcher RL, Schmidt RG, Siegel HJ, Wong MK, Yasko AW, Cancer Network NC. Bone cancer clinical practice guidelines. J Natl Compr Canc Netw 3(2):124-40, 2005. e-Pub 2005. PMID: 19817025.
- Satcher, RL. What factors are associated with local metastatic lesion progression after intramedullary nail stabilization. CORR Insights.
Review Articles
- Satcher RL, Zhang XH. Evolving cancer-niche interactions and therapeutic targets during bone metastasis. Nat Rev Cancer 22(2):85-101, 2022. e-Pub 2022. PMID: 34611349.
- Brozovich A, Garmezy B, Pan T, Wang L, Farach-Carson MC, Satcher RL. All bone metastases are not created equal: Revisiting treatment resistance in renal cell carcinoma. J Bone Oncol 31:100399, 2021. e-Pub 2021. PMID: 34745857.
- Patton KT, Satcher RL, Laskin WB. Capillary hemangioblastoma of soft tissue: report of a case and review of the literature. Hum Pathol 36(10):1135-9, 2005. e-Pub 2005. PMID: 16226115.
Professional Educational Materials
- Maldonado JA, Colbert LE, Gomez MM, Todd SE, Christopherson KM, Ning MS, Grosshans DR, Lin LL, Reddy JP, Bird J, Satcher R, Lewis V, Tang C, Koong AC, Gomez DR. Rapid Access Multidisciplinary Bone Metastases Clinic Decreases Financial Toxicity for Patients Undergoing Palliative Radiation. Elsevier: International Journal of Radiation Oncology*Biology*Physics, 2019.
- Elhammali A, Dabaja B, Gunther JR, Yoder AK, Moon B, Weber D, Thomas S, Andraos T, Garg N, Amini B, Manasanch EE, Patel K, Orlowski R, Lee H, Bird J, Satcher R, Lin P, Pinnix CC, Milgrom SA. Involved Site vs Extended Field Radiation Therapy for Multiple Myeloma of Long Bones after Internal Fixation. Elsevier: International Journal of Radiation Oncology*Biology*Physics, 2018.
- Conley A, Satcher R, Wang W, Lazar AJ, Fox PS, Moon BS, Bird J, Lin P, Araujo DM. Clinical Characteristics and Treatment Outcomes of Clear Cell Chondrosarcomas: MD Anderson Cancer Center Seriew. Journal of Clinical Oncology, 2015.
- Satcher RL. 393143 Space Travel Experience of a Chemical Engineer. Conference: 14 AIChE Annual Meeting, 2014.
- Chung YT, Wang J, Romanchuk JJ, Satcher RL, Levenson AS. Tumor-bone interaction through the ER alpha and ER beta signaling pathways in breast cancer bone metastases. Cancer Treatment Reviews, 2006.
Abstracts
- Garmezy B, Brozovich A, Feng L, Deveza L, Satcher RL. Bone-targeted therapy in patients with renal cell carcinoma bone metastases undergoing palliative surgery. Journal of Clinical Oncology (ASCO) 39(15_suppl.e16572). e-Pub 2021.
- Kim M, Maldonado JA, Alam MB, Pandey P, Nguyen QN, Moon B, Bird J, Satcher R, Lewis V, Lin P, Tang C, Koong AC, Colbert L. Retreatment after Single Fraction Palliative Bone Metastasis Treatment in the Modern Era. International Journal of Radiation Oncology*Biology*Physics 108(3):e177-e178, 2020. e-Pub 2020.
- Maldonado JA, Kim M, Pandey P, Todd S, Christopherson KM, Ning MS, Grosshans DR, Lin LL, Reddy J, Bird JE, Satcher RL, Lewis VO, Tang C, Koong AC, Colbert LE. Use of a rapid access multidisciplinary bone metastases clinic to decrease financial toxicity for patients undergoing single-fraction palliative radiation. Journal of Clinical Oncology (ASCO) 38(29 suppl):24, 2020. e-Pub 2020.
- Pan T, Martinez M, Hubka KM, Song JH, Lin S, Yu G, Lee Y, Gallick GE, Tu S, Harrington DA, Farach-Carson MC, Lin S, Satcher RL. Cabozantinib Reverses Renal Cell Carcinoma–mediated Osteoblast Inhibition in Three-dimensional Coculture In Vitro and Reduces Bone Osteolysis In Vivo. AACR Journal: Molecular Cancer Therapeutics 19(6), 2020. e-Pub 2020.
- Bishop AJ, Bird J, Conley AP, Roland CL, Moon B, Satcher R, Livingston JA, Wang WL, Lazar A, Lewis V, Lin P, Guadagnolo BA. Combined Radiation Therapy and Surgery Results in Improved Local Control for Patients with Extraskeletal Myxoid Chondrosarcomas Which Translates into Lower Risk of Distant Metastases. International Journal of Radiation Oncology*Biology*Physics 105(1):E803, 2019. e-Pub 2019.
- Nguyen QN, Chun SG, Chow E, Komaki R, Liao Z, Zacharia R, Szeto BK, Welsh JW, Hahn SM, Fuller CD, Moon BS, Bird JE, Satcher R, Lin PP, Jeter M, O'Reilly MS, Lewis VO. Single-Fraction Stereotactic vs Conventional Multifraction Radiotherapy for Pain Relief in Patients With Predominantly Nonspine Bone Metastases: A Randomized Phase 2 Trial. JAMA Oncol 5(6):872-878, 2019. e-Pub 2019. PMID: 31021390.
- Colbert LE, Gomez M, Todd S, Tang C, Christopherson K, Grosshans DR, Lin LL, Bird JE, Moon B, Satcher
. Implementation of a rapid access multidisciplinary bone metastases clinic to improve access to care at a large cancer center. Journal of Clinical Oncology 36(34 suppl), 2018. e-Pub 2018. - Lewis VO, DeComas AM, Wen S, Lin PP, Moon BS, Satcher RL, Pollock RE, Thall P. Abstract A63: Outcome disparities in high-grade soft tissue sarcomas: A comprehensive cancer center's experience. Cancer Epidemiology Biomarkers & Prevention 20(10_Supplement), 2011. e-Pub 2011.
- Wang J, Levenson AS, Jarrett J, Laskin WB, Satcher RL. Metastasis Associated Protein 1 (MTA1) was highly expressed and localized in nucleus in prostate cancer bone metastasis. ASBMR, Honolulu, HI, 2007. e-Pub 2007.
- Gupta GR, Cannon CP, Lin PP, Satcher RL, Lewis VO. Hemangioendothelioma of Bone-Surgical Outcme. Musculoskeletal Tumor Society 2007 Annual Meeting, 2007. e-Pub 2007.
- Wang J, Levenson AS, Satcher RL. Stromal-epithelial crosstalk in prostate cancer bone metastasis. Cancer Treatment Reviews 32:S14, 2006. e-Pub 2006.
- Wang J, Levenson AS, Thurn KE, Simons LA, Satcher RL. Gene expression regulated by physical contact between prostate cancer cells and osteoblasts in a heterotypic co-culture system. Journal of Bone and Mineral Research 19:S370, 2004. e-Pub 2004.
- Wang J, Levenson AS, Thurn KE, Simons LA, Satcher RL. Cell proliferation and gene expression were regulated by contact between prostate cancer cells PC3 and primary osteoblasts in different stages of bone metastasis. Proceeding of the American Association for Cancer Research 45:790, 2004. e-Pub 2004.
- Satcher, RL. Orthopaedics, Orbits, and Operating Rooms: Translational Applications for Telemedicine and Telesurgery in Cancer Care. ABJS 2021 Annual Meeting.
- Guadagnolo B, Mitra D, Farooqi A, Hempel C, Dorber C, Mathai R, Willis T, Wang W, Ratan R, Somaiah N, Torres KE, Hunt KK, Scally CP, Keung EZ, Satcher R, Bird J, Lin PP, Moon BS, Lewis VO, Roland CL, Bishop AJ. Prospective single-arm controlled trial of 3-week-course hypofractionated preoperative radiotherapy for soft tissue sarcoma of the extremity or trunk. ESTRO.
Book Chapters
- Satcher, RL. Future of telemedicine. In: Teleneurology: Complete Guide to Implementing Telemedicine and Telebehavioral Health into Your Practice. Elsevier, 181-191, 2021.
- Satcher, RL. Benign Fibrous Tumors. In: Orthopaedic Knowledge Update: Musculoskeletal Tumors 4, 2019.
- Satcher R. Bone Metastasis. In: Encyclopedia of Cancer, 568-573, 2017.
- Frink SJ, Satcher RL. Miscellaneous Benign Soft-Tissue Tumors. In: Orthopaedic Knowledge Update: Musculoskeletal Tumors 3, 287-293, 2014.
- Satcher, RL. Benign Fibrous Tumors. In: Orthopaedic Knowledge Update: Musculoskeletal Tumors. 3, 275-280, 2014.
- Cooper CR, Satcher RL, Gurski L, van Golen KL. Mechanism of metastasis to bone: The role of bone marrow endothelium. In: Bone and Cancer. Springer, 57-72, 2008.
- MacDonald L, Walterhouse D, Satcher RL. Pediatric Bone Tumors. In: Just the Facts in Pediatrics. 1st. McGraw-Hill, 381, 2004.
Books (edited and written)
- Zhao, M, Aintablian, H, Satcher, R, Daneshjou, R, Rosenbach, M. Dermatologic Considerations for Spaceflight and Space Exploration, 2024.
- Satcher, Robert L. National Academies of Sciences, Engineering, and Medicine. The National Academies Press, 2021.
Patient Reviews
CV information above last modified March 30, 2026