Top

Rosa F. Hwang, M.D., F.A.C.S.

Department of Breast Surgical Oncology, Division of Surgery

About Dr. Hwang

As a physician-scientist with fellowship training in surgical oncology, I have an extensive clinical and translational research background in pancreatic cancer and breast cancer. For the past 9 years, my laboratory research has focused on the role of the tumor-associated stroma in pancreatic cancer. For these studies, I use the CCSG resources extensively including the following Core facilities: Genetically Engineered Mouse Facility, Monoclonal Antibody Core, Flow Cytometry and Cellular Imaging, Research Animal Support Facility, Sequencing and Microarray, Tissue Biospecimen and Pathology and the Research Histopathology facility. For my clinical and translational studies in breast cancer, I have used the Biostatistics Resource Group on a regular basis. I depend on these facilities for my academic efforts and I anticipate using these resources in the future.

Meet Rosa Hwang, M.D.

Featured Articles

Illustration of female doctor looking at patient's chest Xray

What is a double mastectomy?

Present Title & Affiliation

Primary Appointment

Co-Lead, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas

Professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Associate Medical Director for Surgery, Department of Nellie B. Connally Breast Center, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1993	University of Maryland at Baltimore, Baltimore, Maryland, US, MD
1989	University of Maryland, College Park, Maryland, US, Zoology and Psychology, BS

Postgraduate Training

2001-2002	Research Fellowship, Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas
2000-2003	Fellowship, Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
1995-1997	Research Fellow, Gene Therapy Laboratories, The University of Southern California-Keck School of Medicine, Los Angeles, California
1993-2000	Resident, General Surgery, The University of Southern California-Keck School of Medicine, Los Angeles, California

Licenses & Certifications

2015	Drug Enforcement Administration
2003	American Board of Surgery
2000	Texas
1994	California

Experience & Service

Faculty Academic Appointments

Associate Professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2018

Associate Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2018

Assistant Professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2004 - 2010

Assistant Professor, Department of Surgical Oncology, University of California, San Diego, San Diego, CA, 2003 - 2004

Administrative Appointments/Responsibilities

Member, Service Line Executive Committee, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present

Co-Lead, Breast Service Line, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present

Section Chief, Clinical Operations, Department of Breast Surgical Oncology, UT MD Anderson Cancer Center, Houston, TX, 2020 - Present

Associate Medical Director for Surgery, Department of Nellie B. Connally Breast Center, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - Present

Residency Program Director, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - 2010

Other Professional Positions

Member, Scientific Advisory Board and Co-Founder, Stellanova Therapeutics Inc, Houston, TX, 2020 - Present

Member, National Academies of Sciences, Engineering, and Medicine; Committee on Diagnosing and Treating Adult Cancers, Washington DC, DC, 2019 - 2021

Consultant, Intuitive Surgical Inc, California, 2017 - Present

Consultant, Physicians Network, MD Anderson Physicians Network, Houston, Texas, 2016 - Present

Member, Society of Surgical Oncology’s (SSO) Annual Cancer Symposium, Houston, TX, 2016 - Present

Member, SSO-Breast Disease Site Working Group, Rosemont, IL, 2016 - Present

Membership Committee Member, Society of University Surgeons, Los Angeles, CA, 2014 - 2017

Breast Content Expert, Society of Surgical Oncology (SSO) - SCORE Committee, Rosemont, IL, 2014 - Present

Committee Member Education Committee, Association for Academic Surgery (AAS), Los Angeles, CA, 2011 - 2013

Committee Member, The Pancreas Club, Inc, Planning Committee 46th Annual Pancreas Club Meeting, San Diego, CA, Carol Stream, IL, 2011

Member, American Society of Breast Surgeons (ASBS) Publications Committee, Columbia, MD, 2009 - Present

Member, AACR Tumor Microenvironment Working Group, Houston, TX, 2008 - Present

Reviewer, Program Committee, Society for Surgery of the Alimentary Tract (SSAT) Annual Meeting, Washington, DC, 2007

Reviewer, Program Committee, Society for Surgery of the Alimentary Tract (SSAT) Annual Meeting, Washington, DC, 2007 - 2008

Member, Society for Surgery of the Alimentary Tract (SSAT), Houston, TX, 2006 - Present

Member, American Pancreatic Association (APA), Houston, TX, 2005 - Present

Cancer Liaison, American College of Surgeons Commission on Cancer, VA San Diego Healthcare System, San Diego, CA, 2004

Extramural Institutional Committee Activities

Member, Navigation Workstream Core Team, Breast Service Line, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2022 - Present

Member, Upstream Capacity Management Core Team, Breast Service Line, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2022 - Present

Committee Member, Minimally Invasive Surgery Taskforce, Division of Surgery, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2021 - Present

Member, Access Redesign Medical Practice Core Team, Breast Service Line, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2021 - Present

Member, Breast Service Line Launch, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2020 - Present

Member, Breast Center Steering Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2018 - Present

Member, Cancer Staging Workgroup, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017

Committee Member, OR Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - Present

Committee Member, Value Analysis Team, Division of Surgery, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - 2024

Member, Epic Education Task Force, Division of Surgery, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - 2020

Member, Division of Surgery EPIC Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2016 - 2020

Member, Faculty Academic Review Committee (FARC), The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2015 - 2016

Member, TissueStation Review Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2015 - 2022

Specialty Group Matter Expert (SME) for Breast, EHR Officer, Department of Surgical Oncology, The University of Texas, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2014 - 2020

Associate Member, Office of Protocol Research - Institutional Review Board 2, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2013 - 2015

Member, Surgical Innovation Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2013

Member, Breast Tissue Oversight Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2012 - 2012

Alternate Member, Institutional Tissue Utilization Committee (iTUC), The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2011 - 2013

Committee Member, Computerized Provider Order Entry (CPOE) Steering Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2010 - 2011

Primary Member, Breast Tissue Oversight Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2010 - 2013

Committee Member, Breast Cancer Screening Guidelines Development Team, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2009 - Present

Member, Clinical Research Committee (CRC), The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2008 - 2011

Member, Biospecimen Repository Advisory Committee (BRAC) - Pancreas Bank, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2008 - 2010

Voting Member, Clinical Effectiveness Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2007 - 2013

Organizing Committee Member, Breast Cancer Research Group Retreat, Triple Negative/Basal-Like Breast Cancers, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2006

Director, Pancreas Satellite Tissue Bank, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2005 - 2010

Editorial Activities

Editorial Board Member, Annals of Surgical Oncology, Breast Oncology Section, 2024 - Present

Editorial Board Member, Scientific Reports, a Nature Research journal, 2015 - Present

Honors & Awards

2022 - 2024	TMCi (Texas Medical Center Innovation) Accelerator for Cancer Therapeutics Program
2022	AIM-HI Women’s Initiative Luncheon & Award Ceremony, 2022 Global Summit on Cancer Research and Entrepreneurship
2020	Faculty Honoree Award for Clinical Quality Improvement, The University of Texas MD Anderson Cancer Center - President's Recognition of Faculty Excellence
2017	Best Doctors in America, Best Doctors
2013	Conquer Cancer Foundation of American Society of Clinical Oncology (ASCO) Merit Award given to Elizabeth FitzSullivan, M.D., Surgical Breast Fellow (supervising faculty, RF Hwang, M.D.), Conquer Cancer Foundation Board of Directors and the Breast Cancer Symposium Program Committee
2012	American Society of Clinical Oncology (ASCO) Conquer Cancer Foundation Merit Award given to Lisa Allen, M.D., Surgical Breast Fellow (supervising faculty, RF Hwang, M.D.), American Society of Clinical Oncology (ASCO) Conquer Cancer Foundation Board of Directors and the Breast Cancer Symposium Program Committee
2011	American Association for Cancer Research (AACR) Scholar-in-Training Award given to Sarah Gainer, M.D. Surgical Breast Fellow (supervising faculty, RF Hwang, M.D.), American Association for Cancer Research (AACR)
2011	Certificate of Excellence, Laboratory Investigation Journal
2010	Marquis Who's Who
2009	Marquis Who's Who in America
2008	Trainee Travel Award for Oral Abstract Presented at "The Chronic Pancreatitis to Pancreatic Cancer Continuum", American Pancreatic Association (Awardee-Armando Rivera, Ph.D.; Supervising Faculty-RF Hwang, MD
2008	America's Top Oncologists, Consumer's Research Council of America
2006	Teaching Award, The University of Texas MD Anderson Cancer Center for Biomedical Engineering
2006 - 2010	Career Development Award, The University of Texas M. D. Anderson Cancer Center Pancreas SPORE Career Development Award (5P20 CA101936), Principal Investigator, The role of tumor-associated stroma in the regulation of pancreatic cancer progression, $50,000 ($50,000/year)
2006 - 2009	Career Development Award, Society for Surgery of the Alimentary Tract (SSAT), Principal, Investigator, Tumor-stromal interactions in the regulation of pancreatic cancer progression, $100,000 ($50,000/year)
2006	Awardee, American Association for Cancer Research Minority Scholar Award in Cancer Research, American Association of Cancer Research
2005	Teaching Award, The University of Texas MD Anderson Cancer Center for Biomedical Engineering
2002	Awardee, Research Fellowship, Method in Clinical Cancer Research Workshop, American Association for Cancer Research/American Society for Clinical Oncology
2001	Awardee, Research Fellowship, Molecular Biology and Clinical Oncology Workshop, American Association for Cancer Research/American Society for Clinical Oncology
1989	Phi Sigma Honor Society
1989	Phi Beta Kappa
1984	Maryland Distinguished Scholar

Professional Memberships

Society for Immunotherapy of Cancer (SITC)

2018 - Present

SSO Breast Disease Site Work Group

2016 - Present

National Institutes of Health/National Cancer Institute (NIH/NCI)

2012 - Present

The Society of University Surgeons

2011 - Present

Harris County Medical Society

2009 - Present

Texas Medical Association

2009 - Present

American Society of Breast Disease

2008 - Present

The Association for Surgical Education

2008 - Present

South Texas Chapter of the American College of Surgeons

2008 - 2011

The American Society of Breast Surgeons

2007 - Present

American College of Surgeons Oncology Group

2006 - Present

Society for Surgery of the Alimentary Tract

2006 - Present

American Pancreatic Association

2005 - Present

American Society of Clinical Oncology

2003 - Present

Association for Academic Surgery

2003 - Present

Pancreas Club

2002 - Present

American Association for Cancer Research

2001 - Present

American College of Surgeons

2000 - Present

Society of Graduate Surgeons of the Los Angeles County/University of Southern California Medical Center

2000 - Present

Society of Surgical Oncology

2000 - Present

Phi Beta Kappa

1989 - Present

Selected Presentations & Talks

Local Presentations

2023. Advances in Breast Conserving Surgery: The Critical Role of Tumor Localization. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
2022. “Innovation in Cancer Therapeutics—Odyssey of a Surgeon-Scientist.”. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
2019. The Multidimensional Role of DKK3 in Cancer. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
2017. “ Breast Conservation with Oncoplastic Reconstruction: Operative and Oncologic Outcomes”. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.

Regional Presentations

2006. The influence of tumor-associated stroma on pancreatic cancer progression. Conference. The University of Texas MD Anderson Cancer Center. Round Top, TX, US.

National Presentations

2025. Developing Robotic-Assisted Mastectomy in the U.S.: From Clinical Need to Surgical Innovation. Invited. North American Surgical Oncology Graduates (NASOG). Houston, Texas, US.
2025. Translating Discovery to Impact: Navigating Biotech Entrepreneurship as an Academic Surgeon. Invited. North American Surgical Oncology Graduates (NASOG). Houston, Texas, US.
2025. Robotic-Assisted Mastectomy. Invited. 5th Surgical Oncology Advanced Practitioner (SOAP) Conference. Houston, Texas, US.
2025. Skipping Surgery: DCIS Treatment Redefined. Invited. 21st Oncology Update: Advances and Controversies Conference. Steamboat, Colorado, US.
2025. Breast Cancer Case Presentations. Panelist. 21st Oncology Update: Advances and Controversies Conference. Steamboat Springs, Colorado, US.
2024. Robotic-Assisted Nipple Sparing Mastectomy: Current Status and Future Directions. Invited. 20th Oncology Updates: Advances and Controversies Conference. Steamboat Springs, Colorado, US.
2023. Breast Cancer Case Presentations. Panelist. 19th Oncology Update: Advances and Controversies. Steamboat Springs, CO, US.
2023. Robotic Skin Sparing Mastectomy and Reconstruction. Invited. Oral Presentation. Steamboat Springs, CO, US.
2022. Update on Robotic NSM. Invited. Breast Cancer Care: Innovation, Disruptive Technologies, and Early Adopters 2022 Tomorrow’s Technologies Today. Rochester, MN, US.
2022. Robotic Mastectomy—the Skeptical Surgeon. Invited. Session: Updates in Nipple Sparing and Robotic Mastectomy. Dallas, TX, US.
2020. Breast Cancer - Case Presentations. Panelist. 18th Oncology Update: Advances and Controversies. Steamboat Springs, CO, US.
2019. Neutralization of Stromal Dickkopf-3 (DKK3) Inhibits Tumor Progression and Prolongs Survival in Pancreatic Adenocarcinoma. Conference. The Society of Surgical Oncology 72nd Annual Cancer Symposium. San Diego, CA, US.
2019. Breast Cancer - Case Presentations. Panelist. 17th Oncology Update: Advances and Controversies. Steamboat Springs, CO, US.
2018. Breast Cancer - Case Presentations. Panelist. 16th Oncology Update: Advances and Controversies. Steamboat Springs, CO, US.
2017. Cost and complication burden of oncoplastic breast conservation compared to other treatment options in women with breast cancer. Conference. 18th Annual Meeting. Las Vegas, NV, US.
2017. Targeting Stromal-Derived Dickkopf-3 (DKK3) for The Treatment of Pancreatic Ductal Adenocarcinoma (PDAC). Conference. AACR Annual Meeting. Washington, DC, US.
2017. Breast Cancer - Case Presentations. Panelist. 15th Oncology Update: Advances and Controversies. Steamboat Springs, CO, US.
2016. Operative and Oncologic Outcomes in 9,861 Patients with Operable Breast Cancer: Single Institution Analysis of Breast Conservation with Oncoplastic Reconstruction. Conference. Annual American Society of Breast Surgeons Meeting. Dallas, TX, US.
2014. A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072. Conference. oral presentation at the American Society of Breast Surgeons 15th Annual Meeting. Las Vegas, NV, US.
2013. Role of stellate cell activation in PDAC. Conference. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Cancer Institute (NCI). Bethesda, MD, US.
2012. Pancreatic Stellate Cells and Metastasis - Scientific Session. Conference. Digestive Disease Week (DDW) 2012. San Diego, CA, US.
2012. Blocking tumor-stromal interactions in pancreatic cancer by targeting stromal-cell derived Dickkopf-3 (DKK3). Conference. 7th Annual Academic Surgical Congress. Las Vegas, NV, US.
2010. Stellate cell-derived Dickkopf-3 (DKK3) induces PDAC tumor progression and chemoreistance. Conference. 41st. Annual Meeting of the American Pancreatic Association. Chicago, IL, US.
2009. Pancreatic stellate cells secrete the WNT inhibitor DKK3, Oral Presentation. Conference. 40th Anniversary Meeting of the American Pancreatic Association and Japan Pancreas Society. Honolulu, HI, US.
2009. Expression profile of pancreatic cancer-associated fibroblasts is distinct from carcinoma cells, Oral Presentation. Conference. The Society of Surgical Oncology 62nd. Annual Cancer Symposium. Phoenix, AZ, US.
2008. Tumor-associated pancreatic stellate cells stimulate angiogenesis in vitro and in an orthotopic model of pancreatic cancer, Oral Presentation. Conference. The Chronic Pancreatitis to Pancreatic Cancer Continuum. Chicago, IL, US.
2008. Incidental cystic lesions of the pancreas: multidisciplinary management of 350 patients, Oral Presentation. Conference. 94th Annual Clinical Congress, American College of Surgeons. San Francisco, CA, US.
2008. Tumor-stromal interactions in the regulation of pancreatic cancer progression, Oral Presentation,. Conference. 49th Annual SSAT Annual Business Meeting. San Diego, CA, US.
2008. Decision making for radiation therapy in patients treated with neoadjuvant therapy, Oral Presentation. Invited. 8th Annual Oncology Update: Advances and Controversies. Park City, UT, US.
2007. Effect on pancreatic tumor-associated stellate cells on pancreatic tumor growth, metastasis and angiogenesis, Oral Presentation. Conference. 98th Annual American Association for Cancer Research Meeting. Los Angeles, CA, US.
2006. Pancreatic cancer-associated stromal cells promote tumor progression and angiogenesis, Oral Presentation. Conference. 40th Annual Pancreas Club Meeting. Los Angeles, CA, US.
2006. Low local-regional failure rates in selected breast cancer patients with tumor-positive sentinel nodes who do not undergo completion axillary dissection, Oral Presentation. Invited. 6th Annual Oncology Update: Advances and Controversies. Park City, UT, US.
2005. Low local-regional failure rates in selected breast cancer patients with tumor-positive sentinel nodes who do not undergo completion axillary dissection, Poster Presentation. Invited. 28th Annual Breast Cancer Symposium. San Antonio, TX, US.
2005. Pancreatic Biospecimen Bank at M. D. Anderson Cancer Center. Invited. National Cancer Institute SPORE Investigators' Workshop. Washington, DC, US.
2005. Effects of Src inhibition in stroma and pancreatic cancer, Oral Presentation. Conference. Society of Surgical Oncology 58th Annual Cancer Symposium. Atlanta, GA, US.
2004. Role of Src in pancreatic cancer and tumor-associated stroma, Poster Presentation. Conference. American Association for Cancer Research/Lustgarten Foundation for Pancreatic Cancer Research, Pancreatic Cancer 2004-Advances and Challenges Conference. San Francisco, CA, US.
2004. Visualization of tumor-host interaction and angiogenesis in orthotopic models of human pancreatic cancer by dual-color fluorescence imaging, Poster Presentation. Conference. 95th Annual Meeting of the American Association for Cancer Research. Orlando, FL, US.
2004. The role of laparoscopic colon resection, Oral Presentation. Invited. University of California, San Diego, 27th Annual Postgraduate Assembly in Surgery. San Diego, CA, US.
2003. Targeted therapy of human pancreatic cancer with RPR127963E, a novel inhibitor of platelet-derived growth factor receptor, in an orthotopic nude mouse model, Oral Presentation. Conference. Society of Surgical Oncology 56th Annual Cancer Symposium. Los Angeles, CA, US.
2002. Targeted therapy of human pancreatic cancer with STI571 (Gleevec) in an orthotopic nude mouse mode, Oral Presentation. Conference. 85th Annual Clinical Congress of the American College of Surgeons. San Francisco, CA, US.
2002. Targeted therapy of human pancreatic cancer with STI571 (Gleevec) in an orthotopic nude mouse model, Poster Presentation. Invited. Pancreas Club Meeting. San Francisco, CA, US.
2002. PEG-interferon-a inhibits tumor growth and improves survival in an orthotopic model of pancreatic cancer, Poster Presentation. Conference. 93rd Annual Meeting of the American Association for Cancer Research. San Francisco, CA, US.
2002. Clinicopathologic factors predicting involvement of nonsentinel axillary nodes in women with breast cancer, Oral Presentation. Conference. Plenary Session, Society of Surgical Oncology 55th Annual Meeting. Denver, CO, US.
2001. Advanced reformatting techniques for multi-slice CT data for planning of surgical treatment in patients with hepatobiliary or pancreatic cancer, Poster Presentation. Invited. Radiological Society of North America 87th Scientific Assembly and Annual Meeting. Chicago, IL, US.
1998. Gene therapy of primary and metastatic pancreas cancer with intraperitoneal retroviral vector bearing wild type p53 gene, Oral Presentation. Conference. Society of University Surgeons 59th Annual Meeting. Milwaukee, WI, US.
1998. Antisense cyclin G1 bearing retroviral vectors as novel treatment for pancreatic cancer, Oral Presentation. Conference. Society of University Surgeons 40th Annual University Surgical Residents' Conference. Milwaukee, WI, US.
1997. In vivo effect of enhanced Herpes simplex thymidine kinase gene expression on pancreas cancer cells using a tetracycline-responsive expression system, Poster Presentation. Conference. American Association for the Study of Liver Diseases 48th Annual Meeting. Chicago, IL, US.
1996. Enhancement of bystander killing in gene therapy for gastrointestinal cancers. Invited. Society of Clinical Surgery 153rd Meeting. Los Angeles, CA, US.
1996. Carotenoids enhance gap junction-mediated bystander effects of the HSV-tk suicide vector, Poster Presentation. Conference. Cold Spring Harbor Laboratories Gene Therapy Meeting. Cold Spring Harbor, NY, US.
1996. Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral HS-tk vector supernatant and ganciclovir. Conference. American Surgical Association 116th Annual Meeting. Phoenix, AZ, US.

International Presentations

2024. Robotic-Assisted Mastectomy: On the Horizon in the U.S. Invited. 12th Annual Symposium Robotic Assisted Microsurgical & Endoscopic Society (RAMSES). Singapore, SG.
2024. Charting a Course in Academic Surgery: Balancing Clinical Care, Research, Leadership and Innovation. Invited. Department of Surgery Grand Rounds, SG.
2023. Robotic-Assisted Nipple Sparing Mastectomy: Current State and Future Directions. Invited. 12th Annual Symposium Robotic Assisted Microsurgical & Endoscopic Society (RAMSES). Istanbul, TR.
2022. Robotic-assisted nipple sparing mastectomy: A Conscious Evolution in the U.S. Invited. 11th Annual Symposium Robotic Assisted Microsurgical & Endoscopic Society (RAMSES). Orlando, US.
2022. Robotic Mastectomy—the Skeptical Surgeon. Invited. Session: Updates in Nipple Sparing and Robotic Mastectomy. Dallas, US.
2019. Neutralization of Stromal Dickkopf-3 (DKK3) Inhibits Tumor Progression and Prolongs Survival in Pancreatic Adenocarcinoma. Invited. The Society of Surgical Oncology 72nd Annual Cancer Symposium. San Diego, US.
2017. Targeting Stromal-Derived Dickkopf-3 (DKK3) for The Treatment of Pancreatic Ductal Adenocarcinoma (PDAC). Invited. AACR Annual Meeting. Washington, US.
2014. Surgical Management of Axillary Lymph Nodes in Breast Cancer: Evolving approaches. Invited. 2014 Hangzhou International Symposium of Oncology (HISO). Hangzhou, CN.
2012. Hedgehog signaling in pancreatic cancer is dependent on stellate cells in a paracrine fashion. Invited. American Pancreatic Association/ International Association of Pancreatology (APA/IAP) Joint Annual Meeting. Miami, US.
2011. The role of immortalized PSCs in cell biology the pancreas. Invited. StellaTUM - Consensus Meeting on Pancreatic Stellate Cells, Tehnische Universitat Munchen. Munich, DE.
2011. The role of PSCs in tumor progression and resistance to therapy. Invited. StellaTUM - Consensus Meeting on Pancreatic Stellate Cells, Tehnische Universitat Munchen. Munich, DE.
2010. Stellate cell-derived Dickkopf-3 (DKK3) induces PDAC tumor progression and chemoreistance. Invited. 41st. Annual Meeting of the American Pancreatic Association. Chicago, US.
2010. Surgical therapy for breast cancer. Invited. Cancer Hospital, Fudan University. Shanghai, CN.
2010. Surgical therapy for breast cancer, 2nd. International Breast Cancer Symposium. Invited. Jiangsu Cancer Hospital, Fudan University, Shanghai. Nanjing, CN.
2009. Pancreatic stellate cells secrete the WNT inhibitor DKK3, Oral Presentation. Invited. 40th Anniversary Meeting of the American Pancreatic Association and Japan Pancreas Society. Honolulu, US.
2009. Breast malignancies: interactive multidisciplinary case discussions. Invited. Medical Chapter of the AUB Alumni Association in joint sponsorship with The Cleveland Clinic Foundation. Beirut, LB.
2009. Expression profile of pancreatic cancer-associated fibroblasts is distinct from carcinoma cells, Oral Presentation. Invited. The Society of Surgical Oncology 62nd. Annual Cancer Symposium. Phoenix, US.
2008. Tumor-associated pancreatic stellate cells stimulate angiogenesis in vitro and in an orthotopic model of pancreatic cancer, Oral Presentation. Invited. The Chronic Pancreatitis to Pancreatic Cancer Continuum. Chicago, US.
2007. Effect on pancreatic tumor-associated stellate cells on pancreatic tumor growth, metastasis and angiogenesis, Oral Presentation. Invited. 98th Annual American Association for Cancer Research Meeting. Los Angeles, US.
2005. Effects of Src inhibition in stroma and pancreatic cancer, Oral Presentation. Invited. Society of Surgical Oncology 58th Annual Cancer Symposium. Atlanta, US.
2004. Role of Src in pancreatic cancer and tumor-associated stroma, Poster Presentation. Invited. American Association for Cancer Research/Lustgarten Foundation for Pancreatic Cancer Research, Pancreatic Cancer 2004-Advances and Challenges Conference. San Francisco, US.
2004. Visualization of tumor-host interaction and angiogenesis in orthotopic models of human pancreatic cancer by dual-color fluorescence imaging, Poster Presentation. Invited. 95th Annual Meeting of the American Association for Cancer Research. Orlando, US.
2003. Targeted therapy of human pancreatic cancer with RPR127963E, a novel inhibitor of platelet-derived growth factor receptor, in an orthotopic nude mouse model, Oral Presentation. Invited. Society of Surgical Oncology 56th Annual Cancer Symposium. Los Angeles, US.
2002. PEG-interferon-a inhibits tumor growth and improves survival in an orthotopic model of pancreatic cancer, Poster Presentation. Invited. 93rd Annual Meeting of the American Association for Cancer Research. San Francisco, US.
2002. Clinicopathologic factors predicting involvement of nonsentinel axillary nodes in women with breast cancer, Oral Presentation. Invited. Plenary Session, Society of Surgical Oncology 55th Annual Meeting. Denver, US.
2002. Antitumor effect of PEG-IFNa in an orthotopic model of pancreas cancer, Poster Presentation. Invited. International Symposium on Anti-Angiogenic Agents. Dallas, US.
1997. In vivo effect of enhanced Herpes simplex thymidine kinase gene expression on pancreas cancer cells using a tetracycline-responsive expression system, Poster Presentation. Invited. American Association for the Study of Liver Diseases 48th Annual Meeting. Chicago, US.
1996. Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral HS-tk vector supernatant and ganciclovir. Invited. American Surgical Association 116th Annual Meeting. Phoenix, US.

Formal Peers

2022. Nipple Sparing Mastectomy. Visiting. Houston, TX, US.
2021. Commission on Cancer, Breast Surgery Standards, Division of Surgery Town Hall. Visiting. Houston, TX, US.
2021. Consensus guidelines for surgical margins in DCIS and invasive carcinoma. Visiting. Houston, TX, US.
2021. Predicting Response to Novel DKK3-Targeted Therapy for Pancreatic Cancer, GI SPORE DRP Project Presentations. Visiting. Houston, TX, US.
2021. Updates on Management of Triple Negative Breast Cancer, Journal Club, Department of Breast Surgical Oncology. Visiting. Houston, TX, US.
2021. Current issues in radiation for breast cancer. Visiting. Houston, TX, US.
2020. Role of oncoplastic reconstruction following breast conserving surgery. Visiting. Houston, TX, US.
2020. Consensus guidelines for surgical margins in DCIS and invasive carcinoma. Visiting. Houston, TX, US.
2020. Role of oncoplastic reconstruction following breast conserving surgery. Visiting. Houston, TX, US.
2020. Robotic-Assisted Nipple Sparing Mastectomy, Innovation Initiatives, Division of Surgery Grand Rounds. Visiting. Houston, TX, US.
2019. Elucidating the Role of DKK3 in TNBC, Triple Negative Breast Cancer Working Group. Visiting. Houston, TX, US.
2019. Review of consensus guidelines for surgical margins in DCIS and invasive carcinoma. Visiting. Houston, TX, US.
2019. The Multi-Dimensional Role of DKK3 in Cancer, Department of Cancer Biology Seminar Series. Visiting. Houston, TX, US.
2019. Targeting Stromal DKK3 in PDAC: the Promise and the Peril, Pancreas Cancer Working Group. Visiting. Houston, TX, US.
2019. Role of oncoplastic reconstruction following breast conserving surgery. Visiting. Houston, TX, US.
2018. Review of Consensus Guidelines for Surgical Margins in DCIS and Invasive Carcinoma. Visiting. Houston, TX, US.
2018. Breast conservation with oncoplastic reconstruction: comparison of surgical approaches. Invited. Saginaw, MI, US.
2017. Discussion of DCIS and Margins. Visiting. Houston, TX, US.
2017. Surgical considerations in neoadjuvant treatment of breast cancer. Invited. Saginaw, MI, US.
2017. Review of Consensus Guidelines on Surgical Margins for Patients with DCIS. Visiting. Houston, TX, US.
2016. “Finishing Fellowship: Transitioning to an Independent Academic Career”. Visiting. Houston, TX, US.
2016. BCT with Oncoplastic Reconstruction—Preliminary Cost Analysis of Local Therapy for Breast Cancer. Visiting. Houston, TX, US.
2014. Current Status of The Pancreas Biospecimen Collection and Future/Ongoing Efforts. Visiting. Houston, TX, US.
2013. Pancreatic stellate cells: biology and clinical relevance. Visiting. Houston, TX, US.
2013. NAC sparing mastectomy reconstruction. Visiting. Houston, TX, US.
2013. Nodal staging of breast cancer - current status and evolving approaches. Visiting. Houston, TX, US.
2013. Targeting PDAC-associated stroma. Visiting. Houston, TX, US.
2012. Sentinel lymph node involvement in breast cancer patients after total mastectomy: Is completion axillary node dissection necessary?. Visiting. Houston, TX, US.
2012. SLN surgery in the setting of neoadjuvant chemotherapy. Visiting. Houston, TX, US.
2011. The use of nomograms in the management of breast cancer. Visiting. Houston, TX, US.
2011. The use of nomograms in the surgical management of breast cancer. Visiting. Houston, TX, US.
2011. Nomograms and other predictive tools in breast cancer. Visiting. Houston, TX, US.
2011. Hedgehog signaling in tumor-stromal interactions in pancreatic cancer. Visiting. Houston, TX, US.
2010. Pro-con debate: elderly patients with breast cancer should be offered state of the art treatment. Visiting. Houston, TX, US.
2010. Lymph node involvement in breast cancer: current status of evaluation and treatment with emerging controversies. Visiting. Houston, TX, US.
2010. Significant changes in the molecular profile of pancreatic cancer with neoadjuvant therapy. Visiting. Houston, TX, US.
2010. Data on the profiling of human pancreas tumor samples after neoadjuvant treatment. Visiting. Houston, TX, US.
2010. Borderline resectable pancreatic cancer. Invited. Hackensack, NJ, US.
2010. Journal Club--Impact and management of small volume metastases in breast cancer. Visiting. Houston, TX, US.
2010. Sentinel lymph node biopsy for breast cancer: Current management and emerging controversies. Visiting. Houston, TX, US.
2010. Minimally invasive ablative techniques for breast cancer. Visiting. Houston, TX, US.
2009. Hedgehog signaling in tumor-stromal interactions in pancreatic cancer. Visiting. Waltham, MA, US.
2009. Management of small volume metastases. Visiting. Houston, TX, US.
2009. The influence of race on triple negative breast cancer. Visiting. Houston, TX, US.
2009. Benign breast lesions - diagnosis and management. Visiting. Houston, TX, US.
2009. Invasive lobular breast cancer. Visiting. Houston, TX, US.
2009. Detection of DCIS: current status and evolving controversies. Visiting. Houston, TX, US.
2009. Modeling tumor-stroma interactions with stellate cells. Visiting. Houston, TX, US.
2009. Surgical decision making for early stage breast cancer. Visiting. Houston, TX, US.
2009. Molecular profiles of pancreatic cancer associated with outcome and treatment effects. Visiting. Houston, TX, US.
2008. Sentinel node biopsy for breast cancer. Invited. Cy-Fair, TX, US.
2008. Sentinel lymph node biopsy: complications and controversies. Visiting. Houston, TX, US.
2008. Targeted therapy for pancreatic cancer. Visiting. Houston, TX, US.
2008. Sentinel lymph node surgery for breast cancer; current concepts and controversies. Visiting. Houston, TX, US.
2008. Sentinel node surgery for breast cancer: predictive models. Visiting. Houston, TX, US.
2008. Interesting case discussions: breast swelling. Visiting. Houston, TX, US.
2008. Influence of the tumor microenvironment on pancreas cancer. Visiting. Houston, TX, US.
2008. Tumor Banking, Database Development. Invited. Worcester, MA, US.
2007. Surgical options for breast cancer. Visiting. Houston, TX, US.
2007. Surgical options for breast cancer. Visiting. Houston, TX, US.
2007. Sentinel lymph node biopsy for breast cancer: current approach and continuing controversies. Invited. Iowa City, IA, US.
2006. Sentinel biopsy and axillary dissection for breast cancer. Visiting. Houston, TX, US.
2006. The influence of stromal factors on the progression of pancreatic cancer. Visiting. Houston, TX, US.
2006. Overview of the pancreas biospecimen collection at M. D. Anderson Cancer Center. Visiting. Houston, TX, US.
2006. Controversies in sentinel lymph node surgery for breast cancer. Visiting. Houston, TX, US.
2006. Tissue acquisition and distribution core. Visiting. Houston, TX, US.
2005. Current controversies in the surgical management of breast cancer patients with a positive sentinel lymph node. Visiting. Houston, TX, US.
2005. Tumor-stromal interactions in pancreatic cancer. Visiting. Houston, TX, US.
2004. Angiogenesis: targeted cancer therapy, Oral Presentation. Invited. San Diego, CA, US.
2003. Recent advances in tumor markers, Oral Presentation. Invited. San Diego, CA, US.
1996. Effect of intraperitoneal delivery of retroviral Herpes simplex thymidine kinase vector and ganciclovir on metastatic pancreas cancer, Poster Presentation. Invited. Gaithersburg, MD, US.
1996. Retinoids enhance gap junction-mediated bystander effects of the Herpes simplex thymidine kinase (HS-tk) suicide vector, Poster Presentation. Invited. Los Angeles, CA, US.

Less

Grant & Contract Support

Date:	2023 - Present
Title:	A Prospective, Multicenter Randomized Controlled Trial (RCT) of the da Vinci® SP™ Surgical System vs Open Surgery in Nipple Sparing Mastectomy (NSM) Procedures
Funding Source:	Intuitive Surgical
Role:	PI

Date:	2023 - 2026
Title:	Enhancing Immune Responses in Pancreatic Cancer by Stromal Inhibition of HIF2
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Collaborator
ID:	FP00014098_Res1; RP230224

Date:	2023 - 2027
Title:	The Role of HIF2 in Pancreatic Ductal Adenocarcinoma
Funding Source:	NIH/NCI
Role:	Co-I
ID:	R01CA269565-01A1

Date:	2022 - 2024
Title:	Development of DKK3-Targeted Therapeutic Antibodies for Cancer
Funding Source:	NIH/NCI
Role:	Co-I

Date:	2022 - 2023
Title:	Development of DKK3-Targeted Therapeutic Antibodies for Cancer, SEED Awards for Product Development Research
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Collaborator and Co-Founder
ID:	DP220028

Date:	2022 - 2026
Title:	BC210331: Role of DKK3 in Triple Negative Breast Cancer Tumor Progression and Resistance to Therapy
Funding Source:	Department of Defense (DOD)
Role:	PI
ID:	W81XWH-22-1-0097

Date:	2021 - 2022
Title:	GI SPORE DRP: Therapeutic Targeting of DKK3 in Pancreatic Cancer and Response to Chemotherapy
Funding Source:	NIH/NCI
Role:	PI
ID:	P50CA221707-03

Date:	2021 - 2021
Title:	Therapeutic Targeting of Dikkopf 3 (DKK3) for Triple Negative Breast Cancer
Funding Source:	The University of Texas MD Anderson Cancer Center Adverse Incident Bridge Funds
Role:	PI

Date:	2020 - 2023
Title:	A Retrospective, Multicenter Study of Open Nipple Sparing Mastectomy (NSM)
Funding Source:	Intuitive Surgical, 2020-0381
Role:	PI

Date:	2020 - 2027
Title:	A Prospective, Multicenter Investigation of the da Vinci® Xi™ Surgical System in Nipple Sparing Mastectomy (NSM) Procedures
Funding Source:	Intuitive Surgical/MDACC Institutional Research Grant, 2019-1258
Role:	PI

Date:	2020 - 2022
Title:	Development of DKK3-Targeted Therapy to Overcome Treatment Resistance in Triple Negative Breast Cancer
Funding Source:	Emerson Collective Cancer Research Fund
Role:	PI
ID:	691244

Date:	2020 - 2023
Title:	Therapeutic Targeting of Dikkopf 3 (DKK3) for Triple Negative Breast Cancer
Funding Source:	Department of Defense (DOD)
Role:	PI
ID:	BC1914686

Date:	2020 - 2021
Title:	Pilot Study Evaluating the Feasibility of Robotic-Assisted Nipple Sparing Mastectomy
Funding Source:	Institutional Research Grant
Role:	PI

Date:	2019 - 2022
Title:	The Role of DKK3 in the Immune Microenvironment of Pancreatic Cancer
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	PI
ID:	RP190331

Date:	2018 - 2019
Title:	Development of Therapeutic Antibodies Targeting DKK3 for the Treatment of Pancreatic Cancer
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	PI
ID:	Early Translational Research Award

Date:	2018 - 2013
Title:	Targeting DKK3 for the Treatment and Prevention of Pancreatic Cancer
Funding Source:	NIH/NCI
Role:	PI

Date:	2017 - 2019
Title:	Inhibition of Stromal-Derived DKK3 to Enhance the Response of Pancreatic Cancer to Immunotherapy
Funding Source:	NIH/NCI
Role:	PI
ID:	1-R21-CA218495-01

Date:	2017 - 2019
Title:	Stromal DKK3 and Pancreatic Cancer Resistance to Immunotherapy
Funding Source:	CRI Clinic and Laboratory Integration Program(CLIP)
Role:	PI

Date:	2016 - 2017
Title:	Targeting DKK3 in the Tumor Microenvironment for the Treatment of Pancreatic Cancer, Bayer Innovation and Discovery Grant
Funding Source:	American Association for Cancer Research (AACR)
Role:	PI

Date:	2015 - 2015
Title:	Overcoming pancreatic cancer resistance to immunotherapy by targeting stromal DKK3
Funding Source:	UTMDACC Institutional Research Grant
Role:	PI

Date:	2015 - 2016
Title:	"Dkk3 blockade to inhibit pancreatic cancer progression and overcome resistance to therapy"
Funding Source:	Elsa U. Pardee Foundation
Role:	PI

Date:	2014 - 2017
Title:	Other Internal Funding (Provost Funds)
Funding Source:	The University of Texas MD Anderson Cancer Center
Role:	PI

Date:	2014 - 2015
Title:	DKK3 blockade to inhibit pancreatic cancer progression and overcome resistance to therapy
Funding Source:	The University of Texas MD Anderson Cancer Center - Knowledge Gaps
Role:	PI

Date:	2014 - 2015
Title:	Project 2 - Modulation of pancreatic cancer immune resistance by pancreatic stellate cells
Funding Source:	MD Anderson Support Grant Multidisciplinary Research Program (MRP)
Role:	Project Leader
ID:	P30CA016672

Date:	2013 - 2014
Title:	Effort, Targeting stromal-derived dikkopf-3 (DKK3) for the prevention and treatment of pancreatic adenocarcinoma
Funding Source:	The University of Texas MD Anderson Cancer Center - Knowledge Gaps
Role:	PI

Date:	2013 - 2015
Title:	Targeting stellate cells for therapy and prevention of pancreatic cancer
Funding Source:	Pancreatic Cancer Action Network (PanCAN)-American Association for Cancer Research (AACR) Innovative Grant
Role:	PI

Date:	2013 - 2014
Title:	Effort, Banking of Normal and Malignant Specimens (Tissue and Blood) from Patients with Pancreatic Adenocarcinoma for The Cancer Genome Atlas (TCGA) Project
Funding Source:	Leidos Biomedical Research
Role:	PI
ID:	Task Order Award (BOA) 13XS034

Date:	2013 - 2016
Title:	Effort, Development of stroma-targeted peptides by phage display selection for therapy and prevention of pancreatic cancer
Funding Source:	The University of Texas MD Anderson Cancer Center Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research
Role:	PI

Date:	2012 - 2012
Title:	Effort, Stroma-targeted therapy of pancreatic cancer: DKK3 inhibition
Funding Source:	IRG - UT MD Anderson Cancer Center
Role:	PI

Date:	2012 - 2013
Title:	Compact permanent magnet MRI system for use in barrier facility
Funding Source:	NIH/NCRR
Role:	Major User

Date:	2012 - 2012
Title:	Effort, Targeting Stromal Dkk3 in Pancreatic Cancer
Funding Source:	Lustgarten Foundation
Role:	PI

Date:	2011 - 2014
Title:	Effort, A Phase II trial exploring the success of cryoablation therapy in the treatment of invasive breast carcinoma
Funding Source:	Brigham and Women's Hospital
Role:	PI
ID:	ACOSOGZ1072 01

Date:	2011 - 2012
Title:	Stromal DKK3 in the chemoresistance of pancreatic cancer
Funding Source:	Metastasis Research Center
Role:	PI

Date:	2011 - 2016
Title:	Effort, The role of stroma-derived Dickkopf-3 (DKK3) in pancreatic cancer resistance to chemotherapy
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Project Leader
ID:	RP110588

Date:	2011 - 2014
Title:	Effort, Conditional ablation of stellate cells to determine their role in pancreatitis and pancreatic cancer
Funding Source:	NIH/NCI
Role:	PI
ID:	2R21CA155650-02

Date:	2011 - 2012
Title:	Effort, Cryoablation treatment of invasive breast carcinoma after chemotherapy
Funding Source:	Hamill Foundation Breast Cryoablation Research Funds
Role:	PI

Date:	2011 - 2013
Title:	Anti-VEGF therapy as a driver of malignant progression of pancreatic cancer
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Collaborator

Date:	2010 - 2015
Title:	Effort, Texas Center for Cancer Nanomedicine
Funding Source:	NIH/NCI
Role:	Co-I
ID:	4U54CA151668-04

Date:	2010 - 2015
Title:	Theranostic Nanoparticles for Targeted Treatment of Pancreatic Cancer
Funding Source:	Emory University
Role:	Collaborator
ID:	3U01CA151810-03

Date:	2010 - 2015
Title:	Effort, The role of the stroma-derived Wnt mediator Dickkopf-3 (DKK3) in pancreatic cancer resistance to therapy
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Co-I
ID:	RP101313

Date:	2010 - 2012
Title:	Effort, Stellate cell-specific targeting in pancreatic cancer
Funding Source:	Pancreatic Cancer Action Network-AACR Innovative Grants
Role:	PI

Date:	2010 - 2012
Title:	Effort, Role of putative Wnt inhibitor Dickkopf-3 in pancreatic tumor-stroma interactions
Funding Source:	NIH/NCI
Role:	PI
ID:	1R21CA149693-01

Date:	2010 - 2012
Title:	Effort, A Phase II trial exploring the success of cryoablation therapy in the treatment of invasive breast carcinoma
Funding Source:	American College of Surgeons (ACS)
Role:	PI
ID:	ACOSOGZ1072 01

Date:	2010 - 2011
Title:	Effort, Wnt signaling in pancreatic cancer associated-stroma
Funding Source:	Lustgarten Foundation
Role:	PI
ID:	RFP10-113

Date:	2010 - 2013
Title:	Effort, The role of periostin in tumor-stromal interactions in pancreatic cancer
Funding Source:	American Cancer Society (ACS)
Role:	PI

Date:	2010 - 2010
Title:	Effort, Determination of the fate of stellate cells in pancreatic cancer
Funding Source:	Lustgarten Foundation
Role:	PI
ID:	RPF10-114

Date:	2009 - 2011
Title:	Effort, Characterization of Dickkopf-3 (DKK3) and the Wnt signaling pathway in the tumor microenvironment of pancreatic cancer
Funding Source:	American Cancer Society Institutional Research Grant
Role:	PI

Date:	2009 - 2015
Title:	Effort, Stromal periostin in pancreatitis and pancreas cancer
Funding Source:	NIH/NCI
Role:	PI
ID:	5K08CA138912-05

Date:	2009 - 2011
Title:	Effort, Hedgehog signaling in tumor-stromal interactions in pancreatic cancer
Funding Source:	AstraZeneca
Role:	PI

Date:	2007 - 2012
Title:	Effort, A preclinical model for pancreatic tumorigenesis: targeting mTor pathway
Funding Source:	NIH/NCI
Role:	Collaborator

Date:	2006 - 2010
Title:	Effort, The role of tumor-associated stroma in the regulation of pancreatic cancer progression
Funding Source:	The University of Texas M. D. Anderson Cancer Center Pancreas SPORE Career Development Award
Role:	PI
ID:	5P20 CA101936

Date:	2006 - 2009
Title:	Effort, Tumor-stromal interactions in the regulation of pancreatic cancer progression
Funding Source:	Society for Surgery of the Alimentary Tract
Role:	PI

Date:	2006 - 2008
Title:	Effort, Diabetes and impaired glucose tolerance in cancer patients
Funding Source:	The University of Texas M. D. Anderson Cancer Center Multidisciplinary Research Program
Role:	Collaborator

Date:	2006 - 2008
Title:	Effort, The effect of S100P on tumor-stromal interactions in pancreatic cancer
Funding Source:	National Pancreas Foundation
Role:	PI

Date:	2005 - 2006
Title:	Effort, Expansion of a multidisciplinary pancreas database
Funding Source:	The University of Texas M.D. Anderson Faculty Oversight Committee for Database Development
Role:	Co-I

Date:	2005 - 2008
Title:	Effort, The role of S100P in tumor-stroma interactions in pancreatic adenocarcinoma
Funding Source:	Texas Federation of Business and Professional Women
Role:	PI

Date:	2003 - 2010
Title:	Effort, Tissue Procurement and Distribution Core C
Funding Source:	The University of Texas M. D. Anderson Cancer Center SPORE in Pancreatic Cancer
Role:	Co-Leader
ID:	5P20 CA101936-05

Date:	2003 - 2004
Title:	Effort, The role of Src in pancreatic cancer
Funding Source:	University of California Academic Senate Grant
Role:	PI

Title:	Modulation of the microenvironment to improve immunotherapy for pancreatic cancer
Funding Source:	The University of Texas MD Anderson Cancer Center Pancreas Moon Shot
Role:	Principal Investigator-MDACC

Selected Publications

Peer-Reviewed Articles

Wanis KN, Mitchell MP, Giordano SH, Litton JK, Shaitelman SF, Tamirisa N, Bedrosian I, Dong W, Shen Y, Hunt KK, Singh P, Sun SX, Caudle AS, Kuerer HM, Meric-Bernstam F, Hwang RF, Adesoye T. Implications of omitting sentinel lymph node biopsy on adjuvant decision making for patients with small breast cancers. Cancer 131(11):e35910, 2025. e-Pub 2025. PMID: 40433858.
Wanis KN, Dong W, Shen Y, Meric-Bernstam F, Adesoye T, Kuerer HM, Caudle AS, Tamirisa N, DeSnyder SM, Sun SX, Bedrosian I, Singh P, Cox SE, Hunt KK, Hwang RF. Predicting pathologic >/=N2 disease in women with breast cancer. NPJ Breast Cancer 11(1):46, 2025. e-Pub 2025. PMID: 40404657.
Weaver OO, Contreras A, Cohen EO, Guirguis MS, Kapoor MM, Scoggins ME, Hwang RF, Candelaria RP, Yang WT, Dennison JB, Sun J, Whitman GJ. Assessment of Pectoralis muscle invasion using combined DBT and contrast-enhanced mammography: Retrospective multi-reader study. Curr Probl Diagn Radiol, 2025. e-Pub 2025. PMID: 40288929.
Kuerer HM, Valero V, Smith BD, Krishnamurthy S, Diego EJ, Johnson HM, Lin H, Shen Y, Lucci A, Shaitelman SF, Mitchell MP, Boughey JC, White RL, Hunt KK, Yang WT, Rauch GM, Study Group ER. Selective Elimination of Breast Surgery for Invasive Breast Cancer: A Nonrandomized Clinical Trial. JAMA Oncol 11(5):529-534, 2025. e-Pub 2025. PMID: 40152443.
Kozlova N, Cruz KA, Doh HM, Ruzette AA, Willis NA, Hong SM, Gonzalez RS, Vyas M, Selfors LM, Dreyer S, Upstill-Goddard R, Faia KL, Wenglowsky S, Close J, Beutel AK, Jutric Z, Oliphant MUJ, Thapa B, Taylor MS, Mustonen V, Mangalath P, Halbrook CJ, Grossman JE, Hwang RF, Clohessy JG, Ruskamo S, Kursula P, Petrova B, Kanarek N, Cole PA, Chang DK, Norrelykke SF, Scully R, Muranen T. A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance. bioRxiv, 2025. e-Pub 2025. PMID: 39896456.
Saito, Y, Xiao, Y, Yao, J, Li, Y, Liu, W, Yuzhalin, A, Shyu, YM, Li, H, Yuan, X, Li, P, Zhang, Q, Li, Z, Wei, Y, Yin, X, Zhao, J, Kariminia, SM, Wu, Y, Wang, J, Yang, JX, Xia, W, Sun, Y, Jho, EH, Chiao, PJ, Hwang, RF, Ying, H, Wang, H, Zhao, Z, Maitra, A, Hung, MC, DePinho, RA, Yu, D. Targeting a chemo-induced adaptive signaling circuit confers therapeutic vulnerabilities in pancreatic cancer. Cell Discovery 10(1), 2024. e-Pub 2024. PMID: 39468013.
Huang ML, Lane DL, Chang Sen LQ, Candelaria RP, Kuerer HM, Hunt KK, Akay C, Lim B, Shaitelman S, Hwang RF, Chen H, Katta R, Santiago L. Defining Breast Cryoablation Treatment Success: A Guide for the Curative and Palliative Treatment of Breast Cancer. Acad Radiol 31(12):4759-4771, 2024. e-Pub 2024. PMID: 39107186.
Wanis K, Goetz L, So A, Glencer AC, Sun SX, Teshome M, Resetkova E, Hwang RF, Hunt KK, Candelaria RP, Huo L, Singh P. The Prevalence of Sentinel Lymph Node Positivity and Implications for the Utility of Frozen Section Diagnosis Following Neoadjuvant Systemic Therapy in Patients with Clinically Node‑Negative HER2‑Positive or Triple‑Negative Breast Cancer. Annals of Surgical Oncology 31(11):7339-7346, 2024. PMID: 39048903.
Yu D, Saito Y, Xiao Y, Yao J, Li Y, Liu W, Yuzhalin A, Shyu YM, Li H, Yuan X, Li P, Zhang Q, Li Z, Wei Y, Yin X, Zhao J, Kariminia S, Wu YC, Wang J, Yang J, Xia W, Sun Y, Jho E, Chiao P, Hwang R, Ying H, Wang H, Zhao Z, Maitra A, Hung MC, DePinho R. Targeting a chemo-induced adaptive signaling circuit confers therapeutic vulnerabilities in pancreatic cancer. Cell Discovery 10(1):109, 2024. e-Pub 2024. PMID: 39468013.
Wanis KN, Goetz L, So A, Glencer AC, Sun SX, Teshome M, Resetkova E, Hwang RF, Hunt KK, Candelaria RP, Huo L, Singh P. ASO Visual Abstract: The Prevalence of Sentinel Lymph Node Positivity and Implications for the Utility of Frozen Section Diagnosis Following Neoadjuvant Systemic Therapy in Patients with Clinically Node-Negative HER2-Positive or Triple-Negative Breast Cancer. Ann Surg Oncol. e-Pub 2024. PMID: 39107599.
Wanis KN, Goetz L, So A, Glencer AC, Sun SX, Teshome M, Resetkova E, Hwang RF, Hunt KK, Candelaria RP, Huo L, Singh P. The Prevalence of Sentinel Lymph Node Positivity and Implications for the Utility of Frozen Section Diagnosis Following Neoadjuvant Systemic Therapy in Patients with Clinically Node-Negative HER2-Positive or Triple-Negative Breast Cancer. Ann Surg Oncol. e-Pub 2024. PMID: 39048903.
Schaverien MV, Singh P, Smith BD, Qiao W, Akay CL, Bloom ES, Chavez-MacGregor M, Chu CK, Clemens MW, Colen JS, Ehlers RA, Hwang RF, Joyner MM, Largo RD, Mericli AF, Mitchell MP, Shuck JW, Tamirisa N, Tripathy D, Villa MT, Woodward WA, Zacharia R, Kuerer HM, Hoffman KE. Premastectomy Radiotherapy and Immediate Breast Reconstruction: A Randomized Clinical Trial. JAMA Netw Open 7(4):e245217, 2024. e-Pub 2024. PMID: 38578640.
Murthy D, Attri KS, Shukla SK, Thakur R, Chaika NV, He C, Wang D, Jha K, Dasgupta A, King RJ, Mulder SE, Souchek J, Gebregiworgis T, Rai V, Patel R, Hu T, Rana S, Kollala SS, Pacheco C, Grandgenett PM, Yu F, Kumar V, Lazenby AJ, Black AR, Ulhannan S, Jain A, Edil BH, Klinkebiel DL, Powers R, Natarajan A, Hollingsworth MA, Mehla K, Ly Q, Chaudhary S, Hwang RF, Wellen KE, Singh PK. Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis. Nat Cell Biol 26(4):613-627, 2024. e-Pub 2024. PMID: 38429478.
Burns, HR, McCarter, JH, King, BW, Yu, JZ, Hwang, RF. Robotic-Assisted Nipple Sparing Mastectomy. Seminars in Plastic Surgery 37(3):176-183, 2024. e-Pub 2024. PMID: 38444956.
Lee JS, Hwang RF. Special Populations/Extremes of Breast Cancer. Surgical Council on Resident Education (SCORE), 2024. e-Pub 2024.
Farley C, Hwang RF. ASO Author Reflections: Preoperative Assessment of Nodal Burden in Breast Cancer. Ann Surg Oncol 31(1):382-383, 2024. e-Pub 2024. PMID: 37861935.
Farley C, Bassett R, Meric-Bernstam F, Bedrosian I, Caudle A, DeSnyder S, Hunt K, Kuerer H, Singh P, Sun S, Tamirisa N, Teshome M, Hwang RF. To Dissect or Not to Dissect: Can We Predict the Presence of Four or More Axillary Lymph Node Metastases in Postmenopausal Women with Clinically Node-Negative Breast Cancer?. Ann Surg Oncol 30(13):8327-8334, 2023. e-Pub 2023. PMID: 37670121.
Zaveri S, Everidge S, FitzSullivan E, Hwang R, Smith BD, Lin H, Shen Y, Lucci A, Teshome M, Sun SX, Hunt KK, Kuerer HM. ASO Visual Abstract: Extremely Low Incidence of Local-Regional Recurrences Observed among T1-2N1 (one or two Positive SLNs) Breast Cancer Patients Receiving Upfront Mastectomy without Completion Axillary Node Dissection. Ann Surg Oncol 30(12):7141-7142, 2023. e-Pub 2023. PMID: 37612547.
Zaveri S, Everidge S, FitzSullivan E, Hwang R, Smith BD, Lin H, Shen Y, Lucci A, Teshome M, Sun SX, Hunt KK, Kuerer HM. Extremely Low Incidence of Local-Regional Recurrences Observed Among T1-2 N1 (1 or 2 Positive SLNs) Breast Cancer Patients Receiving Upfront Mastectomy Without Completion Axillary Node Dissection. Ann Surg Oncol 30(12):7015-7025, 2023. e-Pub 2023. PMID: 37458948.
Johnson HM, Lin H, Shen Y, Diego EJ, Krishnamurthy S, Yang WT, Smith BD, Valero V, Lucci A, Sun SX, Shaitelman SF, Mitchell MP, Boughey JC, White RL, Rauch GM, Kuerer HM, Study Group ER. Patient-Reported Outcomes of Omission of Breast Surgery Following Neoadjuvant Systemic Therapy: A Nonrandomized Clinical Trial. JAMA Netw Open 6(9):e2333933, 2023. e-Pub 2023. PMID: 37707811.
Cooney RA, Saal ML, Geraci KP, Maynard C, Cleaver O, Hoang ON, Moore TT, Hwang RF, Axelrod JD, Vladar EK. A WNT4 and DKK3 driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis. J Cell Sci 136(16), 2023. e-Pub 2023. PMID: 37505110.
Kumar K, Kanojia D, Bentrem DJ, Hwang RF, Butchar JP, Tridandapani S, Munshi HG. Targeting BET proteins decreases hyaluronidase-1 in pancreatic cancer. Cells 12(11), 2023. e-Pub 2023. PMID: 37296612.
Kuerer, HM, Smith, B, Krishnamurthy, S, Yang, WT, Valero, V, Shen, Y, Lin, Y, Lucci, A, Boughey, JC, White, RL, Diego, EJ, Rauch, GM, Moseley, T, van la Parra, RF, Adrada, BE, Leung, J, Sun, SX, Teshome, M, Miggins, MV, Hunt, KK, DeSnyder, SM, Ehlers II, RA, Hwang, RF, Colen, JS, Arribas, E, Samiian, L, Lesnikoski, BA, Piotrowski, MJ, Bedrosian, I, Chong, CD, Correa Refinetti, AP, Huang, ML, Candelaria, RP, Loveland-Jones, C, Mitchell, MP, Shaitelman, SF. Eliminating breast surgery for invasive breast cancer in exceptional responders to neoadjuvant systemic therapy. The lancet oncology 23(12):1517-1524, 2022. e-Pub 2022. PMID: 36306810.
Garcia-Bermudez J, Badgley MA, Prasad S, Baudrier L, Liu Y, La K, Soula M, Williams RT, Yamaguchi N, Hwang RF, Taylor LJ, de Stanchina E, Rostandy B, Alwaseem H, Molina H, Bar-Sagi D, Birsoy K. Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia. Nat Metab 4(6):724-738, 2022. e-Pub 2022. PMID: 35726024.
Boukovalas S, Liu J, Asaad M, Schaverien MV, Akay C, Garvey PB, Hwang RF, Offodile AC. Relationship Between Financial Toxicity and Surgical Treatment for Early-Stage Breast Cancer: A Propensity Score-Matched Comparison of Breast-Conserving Therapy and Mastectomy. J Am Coll Surg 233(3):445-456.e2, 2021. e-Pub 2021. PMID: 34111529.
Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker. Nat Cell Biol 23(6):631-641, 2021. e-Pub 2021. PMID: 34108659.
Mancinelli G, Torres C, Krett N, Bauer J, Castellanos K, McKinney R, Dawson D, Guzman G, Hwang R, Grimaldo S, Grippo P, Jung B. Role of stromal activin A in human pancreatic cancer and metastasis in mice. Sci Rep 11(1):7986, 2021. e-Pub 2021. PMID: 33846512.
Singh P, Tevis SE, Hall CS, Meas S, Hwang RF, Lucci A. Correlation of circulating or disseminated tumor cells with the Oncotype DX Recurrence Score. Breast Cancer Res Treat 184(3):683-687, 2020. e-Pub 2020. PMID: 32888140.
Singh P, Scoggins ME, Sahin AA, Hwang RF, Kuerer HM, Caudle AS, Mittendorf EA, Thompson AM, Bedrosian I, Teshome M, DeSnyder SM, Meric-Bernstam F, Hunt KK. Effectiveness and Safety of Magseed-localization for Excision of Breast Lesions: A Prospective, Phase IV Trial. Ann Surg Open 1(2), 2020. e-Pub 2020. PMID: 34017965.
Principe DR, Narbutis M, Kumar S, Park A, Viswakarma N, Dorman MJ, Kamath SD, Grippo PJ, Fishel ML, Hwang RF, Thummuri D, Underwood PW, Munshi HG, Trevino JG, Rana A. Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy. Cancer Res 80(15):3101-3115, 2020. e-Pub 2020. PMID: 32238357.
Hanson SE, Kapur SK, Garvey PB, Hernandez M, Clemens MW, Hwang RF, Dryden MJ, Butler CE. Oncologic Safety and Surveillance of Autologous Fat Grafting following Breast Conservation Therapy. Plast Reconstr Surg 146(2):215-225, 2020. e-Pub 2020. PMID: 32740564.
Schaverien MV, Kuerer HM, Caudle AS, Smith BD, Hwang RF, Robb GL. Outcomes of Volume Replacement Oncoplastic Breast-Conserving Surgery Using Chest Wall Perforator Flaps: Comparison with Volume Displacement Oncoplastic Surgery and Total Breast Reconstruction. Plast Reconstr Surg 146(1):14-27, 2020. e-Pub 2020. PMID: 32590634.
Hwang RF, Hunt KK. The Emergence of Robotic-assisted Breast Surgery: Proceed With Caution. Ann Surg 271(6):1013-1015, 2020. e-Pub 2020. PMID: 32398613.
Thomas AL, Castellanos K, Mancinelli G, Xia Y, Bauer J, Yazici C, Fantuzzi G, Hwang RF, Krett NL, Papachristou GI, Whitcomb DC, Jung B. Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index. Clin Transl Gastroenterol 11(5), 2020. e-Pub 2020. PMID: 32358238.
Sun S, van la Parra RFD, Rauch GM, Checka C, Tadros AB, Lucci A, Teshome M, Black D, Hwang RF, Smith BD, Krishnamurthy S, Valero V, Yang WT, Kuerer HM. Patient Selection for Clinical Trials Eliminating Surgery for HER2-Positive Breast Cancer Treated with Neoadjuvant Systemic Therapy. Ann Surg Oncol 26(10):3071-3079, 2019. e-Pub 2019. PMID: 31342361.
Weiss A, Lin H, Babiera GV, Bedrosian I, Shaitelman SF, Shen Y, Kuerer HM, Mittendorf EA, Caudle AS, Hunt KK, Hwang RF. Evolution in practice patterns of axillary management following mastectomy in patients with 1-2 positive sentinel nodes. Breast Cancer Res Treat 176(2):435-444, 2019. e-Pub 2019. PMID: 31025270.
Auciello FR, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, Tumanov S, Allen-Petersen BL, Link J, Kendsersky ND, Vringer E, Schug M, Novo D, Hwang RF, Evans RM, Nixon C, Dorrell C, Morton JP, Norman JC, Sears RC, Kamphorst JJ, Sherman MH. A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression. Cancer Discov 9(5):617-627, 2019. e-Pub 2019. PMID: 30837243.
Tevis SE, Bassett R, Bedrosian I, Barcenas CH, Black DM, Caudle AS, DeSnyder SM, Fitzsullivan E, Hunt KK, Kuerer HM, Lucci A, Meric-Bernstam F, Mittendorf EA, Park K, Teshome M, Thompson AM, Hwang RF. OncotypeDX Recurrence Score Does Not Predict Nodal Burden in Clinically Node Negative Breast Cancer Patients. Ann Surg Oncol 26(3):815-820, 2019. e-Pub 2019. PMID: 30556120.
Tadros AB, Smith BD, Shen Y, Lin H, Krishnamurthy S, Lucci A, Barcenas CH, Hwang RF, Rauch G, Santiago L, Strom EA, DeSnyder SM, Yang WT, Black DM, Albarracin CT, Chavez-MacGregor M, Hunt KK, Kuerer HM. Ductal Carcinoma In Situ and Margins <2?mm: Contemporary Outcomes With Breast Conservation. Ann Surg 269(1):150-157, 2019. e-Pub 2019. PMID: 28742682.
Alexander MS, O'Leary BR, Wilkes JG, Gibson AR, Wagner BA, Du J, Sarsour E, Hwang RF, Buettner GR, Cullen JJ. Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer. Radiat Res 191(1):43-51, 2019. e-Pub 2019. PMID: 30376411.
Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, Ramachandran V, Arumugam T, Niehrs C, Wang H, Chiao P, Ling J, Curran MA, Maitra A, Hung MC, Lee JE, Logsdon CD, Hwang RF. Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma. Sci Transl Med 10(464), 2018. e-Pub 2018. PMID: 30355799.
Ebine K, Kumar K, Pham TN, Shields MA, Collier KA, Shang M, DeCant BT, Urrutia R, Hwang RF, Grimaldo S, Principe DR, Grippo PJ, Bentrem DJ, Munshi HG. Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells. Sci Rep 8(1):13225, 2018. e-Pub 2018. PMID: 30185888.
Weiss A, Mittendorf EA, DeSnyder SM, Hwang RF, Bea V, Bedrosian I, Hoffman K, Adrade B, Sahin AA, Kuerer HM, Hunt KK, Caudle AS. Expanding Implementation of ACOSOG Z0011 in Surgeon Practice. Clin Breast Cancer 18(4):276-281, 2018. e-Pub 2018. PMID: 29100726.
Kuerer HM, Rauch GM, Krishnamurthy S, Adrada BE, Caudle AS, DeSnyder SM, Black DM, Santiago L, Hobbs BP, Lucci A, Gilcrease M, Hwang RF, Candelaria RP, Chavez-MacGregor M, Smith BD, Arribas E, Moseley T, Teshome M, Miggins MV, Valero V, Hunt KK, Yang WT. A Clinical Feasibility Trial for Identification of Exceptional Responders in Whom Breast Cancer Surgery Can Be Eliminated Following Neoadjuvant Systemic Therapy. Ann Surg 267(5):946-951, 2018. e-Pub 2018. PMID: 28549010.
Orozco CA, Martinez-Bosch N, Guerrero PE, Vinaixa J, Dalotto-Moreno T, Iglesias M, Moreno M, Djurec M, Poirier F, Gabius HJ, Fernandez-Zapico ME, Hwang RF, Guerra C, Rabinovich GA, Navarro P. Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk. Proc Natl Acad Sci U S A 115(16):E3769-E3778, 2018. e-Pub 2018. PMID: 29615514.
Chakravarthy D, Muñoz AR, Su A, Hwang RF, Keppler BR, Chan DE, Halff G, Ghosh R, Kumar AP. Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1. Cancer Lett 419:103-115, 2018. e-Pub 2018. PMID: 29414301.
Akay CL, Albarracin C, Torstenson T, Bassett R, Mittendorf EA, Yi M, Kuerer HM, Babiera GV, Bedrosian I, Hunt KK, Hwang RF. Factors impacting the accuracy of intra-operative evaluation of sentinel lymph nodes in breast cancer. Breast J 24(1):28-34, 2018. e-Pub 2018. PMID: 28608612.
. Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma. Cancer Cell 32(2):185-203.e13, 2017. e-Pub 2017. PMID: 28810144.
Tadros AB, Yang WT, Krishnamurthy S, Rauch GM, Smith BD, Valero V, Black DM, Lucci A, Caudle AS, DeSnyder SM, Teshome M, Barcenas CH, Miggins M, Adrada BE, Moseley T, Hwang RF, Hunt KK, Kuerer HM. Identification of Patients With Documented Pathologic Complete Response in the Breast After Neoadjuvant Chemotherapy for Omission of Axillary Surgery. JAMA Surg 152(7):665-670, 2017. e-Pub 2017. PMID: 28423171.
Gomez-Chou SB, Swidnicka-Siergiejko AK, Badi N, Chavez-Tomar M, Lesinski GB, Bekaii-Saab T, Farren MR, Mace TA, Schmidt C, Liu Y, Deng D, Hwang RF, Zhou L, Moore T, Chatterjee D, Wang H, Leng X, Arlinghaus RB, Logsdon CD, Cruz-Monserrate Z. Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment. Cancer Res 77(10):2647-2660, 2017. e-Pub 2017. PMID: 28249896.
FitzSullivan E, Bassett RL, Kuerer HM, Mittendorf EA, Yi M, Hunt KK, Babiera GV, Caudle AS, Black DM, Bedrosian I, Reyna C, Teshome M, Meric-Bernstam F, Hwang R. Outcomes of Sentinel Lymph Node-Positive Breast Cancer Patients Treated with Mastectomy Without Axillary Therapy. Ann Surg Oncol 24(3):652-659, 2017. e-Pub 2017. PMID: 27822630.
Roy I, Boyle KA, Vonderhaar EP, Zimmerman NP, Gorse E, Mackinnon AC, Hwang RF, Franco-Barraza J, Cukierman E, Tsai S, Evans DB, Dwinell MB. Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma. Lab Invest 97((3))::302-317,, 2017. e-Pub 2017. PMID: 28092365.
Kumar K, DeCant BT, Grippo PJ, Hwang RF, Bentrem DJ, Ebine K, Munshi HG. BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo. JCI Insight 2(3):e88032, 2017. e-Pub 2017. PMID: 28194432.
Wang Y, Hsu JM, Kang Y, Wei Y, Lee PC, Chang SJ, Hsu YH, Hsu JL, Wang HL, Chang WC, Li CW, Liao HW, Chang SS, Xia W, Ko HW, Chou CK, Fleming JB, Wang H, Hwang RF, Chen Y, Qin J, Hung MC. Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation. Cancer Res 76(23):7049-7058, 2016. e-Pub 2016. PMID: 27758883.
Ware MJ, Keshishian V, Law JJ, Ho JC, Favela CA, Rees P, Smith B, Mohammad S, Hwang RF, Rajapakshe K, Coarfa C, Huang S, Edwards DP, Corr SJ, Godin B, Curley SA. Generation of an in vitro 3D PDAC stroma rich spheroid model. Biomaterials 108:129-42, 2016. e-Pub 2016. PMID: 27627810.
Carter SA, Lyons GR, Kuerer HM, Bassett RL, Oates S, Thompson A, Caudle AS, Mittendorf EA, Bedrosian I, Lucci A, DeSnyder SM, Babiera G, Yi M, Baumann DP, Clemens MW, Garvey PB, Hunt KK, Hwang RF. Operative and Oncologic Outcomes in 9861 Patients with Operable Breast Cancer: Single-Institution Analysis of Breast Conservation with Oncoplastic Reconstruction. Ann Surg Oncol 23(10):3190-8, 2016. e-Pub 2016. PMID: 27406093.
Simmons RM, Ballman KV, Cox C, Carp N, Sabol J, Hwang RF, Attai D, Sabel M, Nathanson D, Kenler A, Gold L, Kaufman C, Han L, Bleznak A, Stanley Smith J, Holmes D, Fornage B, Le-Petross C, Hoda S, McCall L, Hunt KK, investigators A. A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072. Ann Surg Oncol 23(8):2438-45, 2016. e-Pub 2016. PMID: 27221361.
Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature 536(7617):479-83, 2016. e-Pub 2016. PMID: 27509858.
Fayanju OM, Mayo TL, Spinks TE, Lee S, Barcenas CH, Smith BD, Giordano SH, Hwang RF, Ehlers RA, Selber JC, Walters R, Tripathy D, Hunt KK, Buchholz TA, Feeley TW, Kuerer HM. Value-Based Breast Cancer Care: A Multidisciplinary Approach for Defining Patient-Centered Outcomes. Ann Surg Oncol 23(8):2385-90, 2016. e-Pub 2016. PMID: 26979306.
Principe DR, DeCant B, Diaz AM, Mangan RJ, Hwang R, Lowy A, Shetuni BB, Sreekumar BK, Chung C, Bentrem DJ, Munshi HG, Jung B, Grippo PJ, Bishehsari F. PEDF inhibits pancreatic tumorigenesis by attenuating the fibroinflammatory reaction. Oncotarget 7(19):28218-34, 2016. e-Pub 2016. PMID: 27058416.
Principe DR, DeCant B, Mascariñas E, Wayne EA, Diaz AM, Akagi N, Hwang RF, Pasche B, Dawson DW, Fang D, Bentrem DJ, Munshi HG, Jung B, Grippo PJ. TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis. Cancer Res 76(9):2525-39, 2016. e-Pub 2016. PMID: 26980767.
Caudle AS, Yang WT, Krishnamurthy S, Mittendorf EA, Black DM, Gilcrease MZ, Bedrosian I, Hobbs BP, DeSnyder SM, Hwang RF, Adrada BE, Shaitelman SF, Chavez-MacGregor M, Smith BD, Candelaria RP, Babiera GV, Dogan BE, Santiago L, Hunt KK, Kuerer HM. Improved Axillary Evaluation Following Neoadjuvant Therapy for Patients With Node-Positive Breast Cancer Using Selective Evaluation of Clipped Nodes: Implementation of Targeted Axillary Dissection. J Clin Oncol 34(10):1072-8, 2016. e-Pub 2016. PMID: 26811528.
Zhao J, Wu C, Abbruzzese J, Hwang RF, Li C. Cyclopamine-loaded core-cross-linked polymeric micelles enhance radiation response in pancreatic cancer and pancreatic stellate cells. Mol Pharm 12(6):2093-100, 2015. e-Pub 2015. PMID: 25936695.
Caudle AS, Yang WT, Mittendorf EA, Black DM, Hwang RF, Hobbs B, Hunt KK, Krishnamurthy S, Kuerer HM. Selective surgical localization of axillary lymph nodes containing metastases in patients with breast cancer: a prospective feasibility trial. JAMA Surg 150(2):137-43, 2015. e-Pub 2015. PMID: 25517573.
Gonzalez-Villasana V, Rodriguez-Aguayo C, Arumugam T, Cruz-Monserrate Z, Fuentes-Mattei E, Deng D, Hwang RF, Wang H, Ivan C, Garza RJ, Cohen E, Gao H, Armaiz-Pena GN, Del C Monroig-Bosque P, Philip B, Rashed MH, Aslan B, Erdogan MA, Gutierrez-Puente Y, Ozpolat B, Reuben JM, Sood AK, Logsdon C, Lopez-Berestein G. Bisphosphonates Inhibit Stellate Cell Activity and Enhance Antitumor Effects of Nanoparticle Albumin Bound-Paclitaxel in Pancreatic Ductal Adenocarcinoma. Mol Cancer Ther 13(11):2583-94, 2014. e-Pub 2014. PMID: 25193509.
Haynes AB, Bloom ES, Bedrosian I, Kuerer HM, Hwang RF, Munsell MF, Chemaly RF, Graviss LS, Caudle AS, Hunt KK, Tereffe W, Shaitelman SF, Babiera GV. Timing of Infectious Complications Following Breast-Conserving Therapy with Catheter-Based Accelerated Partial Breast Irradiation. Ann Surg Oncol 21(8):2512-6, 2014. e-Pub 2014. PMID: 24736987.
Meric-Bernstam F, Akcakanat A, Chen H, Sahin A, Tarco E, Carkaci S, Adrada BE, Singh G, Do KA, Garces ZM, Mittendorf E, Babiera G, Bedrosian I, Hwang RF, Krishnamurthy S, Symmans WF, Gonzalez-Angulo AM, Mills GB. Influence of biospecimen variables on proteomic biomarkers in breast cancer. Clin Cancer Res 20(14):3870-83, 2014. e-Pub 2014. PMID: 24895461.
Martínez-Bosch N, Fernández-Barrena MG, Moreno M, Ortiz-Zapater E, Munné-Collado J, Iglesias M, André S, Gabius HJ, Hwang RF, Poirier F, Navas C, Guerra C, Fernández-Zapico ME, Navarro P. Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation. Cancer Res 74(13):3512-24, 2014. e-Pub 2014. PMID: 24812270.
Goicoechea SM, García-Mata R, Staub J, Valdivia A, Sharek L, McCulloch CG, Hwang RF, Urrutia R, Yeh JJ, Kim HJ, Otey CA. Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts. Oncogene 33(10):1265-73, 2014. e-Pub 2014. PMID: 23524582.
Caudle AS, Yi M, Hoffman KE, Mittendorf EA, Babiera GV, Hwang RF, Meric-Bernstam F, Sahin AA, Hunt KK. Impact of Identification of Internal Mammary Sentinel Lymph Node Metastasis in Breast Cancer Patients. Ann Surg Oncol 21(1):60-5, 2014. e-Pub 2014. PMID: 24046126.
Fitzsullivan E, Lari SA, Smith B, Caudle AS, Krishnamurthy S, Lucci A, Mittendorf EA, Babiera GV, Black DM, Wagner JL, Bedrosian I, Woodward W, Gainer SM, Hwang RF, Meric-Bernstam F, Hunt KK, Kuerer HM. Incidence and consequence of close margins in patients with ductal carcinoma in situ treated with mastectomy: Is further therapy warranted?. Ann Surg Oncol 20(13):4103-12, 2013. e-Pub 2013. PMID: 23975313.
Bhosale P, Balachandran A, Wang H, Wei W, Hwang RF, Fleming JB, Varadhachary G, Charnsangavej C, Tamm E. CT imaging features of acinar cell carcinoma and its hepatic metastases. Abdom Imaging 38(6):1383-90, 2013. e-Pub 2013. PMID: 23232580.
Shields MA, Ebine K, Sahai V, Kumar K, Siddiqui K, Hwang RF, Grippo PJ, Munshi HG. Snail cooperates with KrasG12D to promote pancreatic fibrosis. Mol Cancer Res 11(9):1078-87, 2013. e-Pub 2013. PMID: 23761168.
Ma Y, Hwang RF, Logsdon CD, Ullrich SE. Dynamic mast cell-stromal cell interactions promote growth of pancreatic cancer. Cancer Res 73(13):3927-37, 2013. e-Pub 2013. PMID: 23633481.
Charo C, Holla V, Arumugam T, Hwang RF, Yang P, Dubois RN, Menter DG, Logsdon CD, Ramachandran V. Prostaglandin E2 regulates pancreatic stellate cell activity via the EP4 receptor. Pancreas 42(3):467-74, 2013. e-Pub 2013. PMID: 23090667.
Yi M, Kuerer HM, Mittendorf EA, Hwang RF, Caudle AS, Bedrosian I, Meric-Bernstam F, Wagner JL, Hunt KK. Impact of the American College of Surgeons Oncology Group Z0011 criteria applied to a contemporary patient population. J Am Coll Surg 216(1):105-13, 2013. e-Pub 2013. PMID: 23122536.
Overman MJ, Zhang J, Kopetz S, Davies M, Jiang ZQ, Stemke-Hale K, Rümmele P, Pilarsky C, Grützmann R, Hamilton S, Hwang RF, Abbruzzese JL, Varadhachary G, Broom B, Wang H. Correction: Gene Expression Profiling of Ampullary Carcinomas Classifies Ampullary Carcinomas into Biliary-Like and Intestinal-Like Subtypes That Are Prognostic of Outcome. PLoS One 8(7), 2013. e-Pub 2013. PMID: 23776447.
Kong AL, Tereffe W, Hunt KK, Yi M, Kang T, Weatherspoon K, Mittendorf EA, Bedrosian I, Hwang RF, Babiera GV, Buchholz TA, Meric-Bernstam F. Impact of internal mammary lymph node drainage identified by preoperative lymphoscintigraphy on outcomes in patients with stage I to III breast cancer. Cancer 118(24):6287-96, 2012. e-Pub 2012. PMID: 22648744.
Alvarado R, Lari SA, Roses RE, Smith BD, Yang W, Mittendorf EA, Arun BK, Lucci A, Babiera GV, Wagner JL, Caudle AS, Meric-Bernstam F, Hwang RF, Bedrosian I, Hunt KK, Kuerer HM. Biology, treatment, and outcome in very young and older women with DCIS. Ann Surg Oncol 19(12):3777-84, 2012. e-Pub 2012. PMID: 22622473.
Alvarado R, Yi M, Le-Petross H, Gilcrease M, Mittendorf EA, Bedrosian I, Hwang RF, Caudle AS, Babiera GV, Akins JS, Kuerer HM, Hunt KK. The role for sentinel lymph node dissection after neoadjuvant chemotherapy in patients who present with node-positive breast cancer. Ann Surg Oncol 19(10):3177-84, 2012. e-Pub 2012. PMID: 22772869.
Hwang RF, Moore TT, Hattersley MM, Scarpitti M, Yang B, Devereaux E, Ramachandran V, Arumugam T, Ji B, Logsdon CD, Brown JL, Godin R. Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer. Mol Cancer Res 10(9):1147-57, 2012. e-Pub 2012. PMID: 22859707.
Kim MP, Truty MJ, Choi W, Kang Y, Chopin-Lally X, Gallick GE, Wang H, McConkey DJ, Hwang RF, Logsdon C, Abbruzzesse J, Fleming JB. Molecular Profiling of Direct Xenograft Tumors Established from Human Pancreatic Adenocarcinoma After Neoadjuvant Therapy. Ann Surg Oncol 19 Suppl 3:395-403, 2012. e-Pub 2012. PMID: 21701930.
Wagner JL, Fearmonti R, Hunt KK, Hwang RF, Meric-Bernstam F, Kuerer HM, Bedrosian I, Crosby MA, Baumann DP, Ross MI, Feig BW, Krishnamurthy S, Hernandez M, Babiera GV. Prospective evaluation of the nipple-areola complex sparing mastectomy for risk reduction and for early-stage breast cancer. Ann Surg Oncol 19(4):1137-44, 2012. e-Pub 2012. PMID: 21979111.
Yi M, Meric-Bernstam F, Kuerer HM, Mittendorf EA, Bedrosian I, Lucci A, Hwang RF, Crow JR, Luo S, Hunt KK. Evaluation of a breast cancer nomogram for predicting risk of ipsilateral breast tumor recurrences in patients with ductal carcinoma in situ after local excision. J Clin Oncol 30(6):600-7, 2012. e-Pub 2012. PMID: 22253459.
Erkan M, Adler G, Apte MV, Bachem MG, Buchholz M, Detlefsen S, Esposito I, Friess H, Gress TM, Habisch HJ, Hwang RF, Jaster R, Kleeff J, Klöppel G, Kordes C, Logsdon CD, Masamune A, Michalski CW, Oh J, Phillips PA, Pinzani M, Reiser-Erkan C, Tsukamoto H, Wilson J. StellaTum: current consensus and discussion on pancreatic stellate cell research. Gut 61(2):172-8, 2012. e-Pub 2012. PMID: 22115911.
Mittendorf EA, Hunt KK, Boughey JC, Bassett R, Degnim AC, Harrell R, Yi M, Meric-Bernstam F, Ross MI, Babiera GV, Kuerer HM, Hwang RF. Incorporation of sentinel lymph node metastasis size into a nomogram predicting non-sentinel lymph node involvement in breast cancer patients with a positive sentinel lymph node. Ann Surg 255(1):109-15, 2012. e-Pub 2012. PMID: 22167004.
Stokes JB, Adair SJ, Slack-Davis JK, Walters DM, Tilghman RW, Hershey ED, Lowrey B, Thomas KS, Bouton AH, Hwang RF, Stelow EB, Parsons JT, Bauer TW. Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment. Mol Cancer Ther 10(11):2135-45, 2011. e-Pub 2011. PMID: 21903606.
Krantz SB, Shields MA, Dangi-Garimella S, Cheon EC, Barron MR, Hwang RF, Rao MS, Grippo PJ, Bentrem DJ, Munshi HG. MT1-MMP cooperates with KrasG12D to promote pancreatic fibrosis through increased TGF-{beta} signaling. Mol Cancer Res 9(10):1294-304, 2011. e-Pub 2011. PMID: 21856775.
Caudle AS, Hunt KK, Kuerer HM, Meric-Bernstam F, Lucci A, Bedrosian I, Babiera GV, Hwang RF, Ross MI, Feig BW, Hoffman K, Litton JK, Sahin AA, Yang W, Hortobagyi GN, Buchholz TA, Mittendorf EA. Multidisciplinary Considerations in the Implementation of the Findings from the American College of Surgeons Oncology Group (ACOSOG) Z0011 Study: A Practice-Changing Trial. Ann Surg Oncol 18(9):2407-12, 2011. e-Pub 2011. PMID: 21327455.
Arumugam T, Brandt W, Ramachandran V, Moore TT, Wang H, May FE, Westley BR, Hwang RF, Logsdon CD. Trefoil factor 1 stimulates both pancreatic cancer and stellate cells and increases metastasis. Pancreas 40(6):815-22, 2011. e-Pub 2011. PMID: 21747314.
Yi M, Buchholz TA, Meric-Bernstam F, Bedrosian I, Hwang RF, Ross MI, Kuerer HM, Luo S, Gonzalez-Angulo AM, Buzdar AU, Symmans WF, Feig BW, Lucci A, Huang EH, Hunt KK. Classification of ipsilateral breast tumor recurrences after breast conservation therapy can predict patient prognosis and facilitate treatment planning. Ann Surg 253(3):572-9, 2011. e-Pub 2011. PMID: 21209588.
Valero V, Kong AL, Hunt KK, Yi M, Hwang RF, Meric-Bernstam F, Bedrosian I, Ross MI, Babiera GV, Litton JK, Mittendorf EA. Sentinel lymph node dissection is technically feasible in older breast cancer patients. Clin Breast Cancer 10(6):477-82, 2010. e-Pub 2010. PMID: 21147692.
Sharma R, Bedrosian I, Lucci A, Hwang RF, Rourke LL, Qiao W, Buchholz TA, Kronowitz SJ, Krishnamurthy S, Babiera GV, Gonzalez-Angulo AM, Meric-Bernstam F, Mittendorf EA, Hunt KK, Kuerer HM. Present-Day Locoregional Control in Patients with T1 or T2 Breast Cancer with 0 and 1 to 3 Positive Lymph Nodes After Mastectomy Without Radiotherapy. Ann Surg Oncol 17(11):2899-908, 2010. e-Pub 2010. PMID: 20443145.
Kang T, Yi M, Hunt KK, Mittendorf EA, Babiera GV, Kuerer H, Bedrosian I, Hwang RF, Lucci A, Meric-Bernstam F. Does blue dye contribute to success of sentinel node mapping for breast cancer?. Ann Surg Oncol 17(Suppl 3):280-5, 2010. e-Pub 2010. PMID: 20853047.
Yi M, Giordano SH, Meric-Bernstam F, Mittendorf EA, Kuerer HM, Hwang RF, Bedrosian I, Rourke L, Hunt KK. Trends in and outcomes from sentinel lymph node biopsy (SLNB) alone vs. SLNB with axillary lymph node dissection for node-positive breast cancer patients: experience from the SEER database. Ann Surg Oncol 17(Suppl 3):343-51, 2010. e-Pub 2010. PMID: 20853057.
Bose D, Tamm E, Liu J, Marcal L, Balachandran A, Bhosale P, Fleming JB, Lee JE, Evans DB, Hwang RF. Multidisciplinary management strategy for incidental cystic lesions of the pancreas. J Am Coll Surg 211(2):205-215, 2010. e-Pub 2010. PMID: 20670858.
Song S, Duan X, Hwang RF, Hafley M, Guha S, Logsdon CD, Bresalier RS. 132 Galectin-3 Induces Human Pancreatic Stellate Cell Activation and IL-8 Production via NF-kB Signaling. Gastroenterology 138(5). e-Pub 2010.
Silberfein EJ, Hunt KK, Broglio K, Shen J, Sahin A, Le-Petross H, Oh J, Litton J, Hwang RF, Mittendorf EA. Clinicopathologic factors associated with involved margins after breast-conserving surgery for invasive lobular carcinoma. Clin Breast Cancer 10(1):52-8, 2010. e-Pub 2010. PMID: 20133259.
Goicoechea SM, Bednarski B, Stack C, Cowan DW, Volmar K, Thorne L, Cukierman E, Rustgi AK, Brentnall T, Hwang RF, McCulloch CA, Yeh JJ, Bentrem DJ, Hochwald SN, Hingorani SR, Kim HJ, Otey CA. Isoform-specific upregulation of palladin in human and murine pancreas tumors. PLoS One 5(4):e10347, 2010. e-Pub 2010. PMID: 20436683.
Hunt KK, Yi M, Mittendorf EA, Guerrero C, Babiera GV, Bedrosian I, Hwang RF, Kuerer HM, Ross MI, Meric-Bernstam F. Sentinel lymph node surgery after neoadjuvant chemotherapy is accurate and reduces the need for axillary dissection in breast cancer patients. Ann Surg 250(4):558-564, 2009. e-Pub 2009. PMID: 19730235.
Katz MH, Wang H, Fleming JB, Sun CC, Hwang RF, Wolff RA, Varadhachary G, Abbruzzese JL, Crane CH, Krishnan S, Vauthey JN, Abdalla EK, Lee JE, Pisters PW, Evans DB. Long-term survival after multidisciplinary management of resected pancreatic adenocarcinoma. Ann Surg Oncol 16(4):836-847, 2009. e-Pub 2009. PMID: 19194760.
Krishnamurthy S, Meric-Bernstam F, Lucci A, Hwang RF, Kuerer HM, Babiera G, Ames FC, Feig BW, Ross MI, Singletary E, Hunt KK, Bedrosian I. A prospective study comparing touch imprint cytology, frozen section analysis and rapid cytokeratin immunostain for intraoperative evaluation of axillary sentinel lymph nodes in breast cancer. Cancer 115(7):1555-1562, 2009. e-Pub 2009. PMID: 19195040.
Yi M, Meric-Bernstam F, Middleton LP, Arun BK, Bedrosian I, Babiera GV, Hwang RF, Kuerer HM, Yang W, Hunt KK. Predictors of contralateral breast cancer in patients with unilateral breast cancer undergoing contralateral prophylactic mastectomy. Cancer 115(5):962-971, 2009. e-Pub 2009. PMID: 19172584.
Ramachandran V, Arumugam T, Langley R, Hwang RF, Vivas-Mejia P, Sood AK, Lopez-Berestein G, Logsdon CD. The ADMR Receptor Mediates the Effects of Adrenomedullin on Pancreatic Cancer Cells and on Cells of the Tumor Microenvironment. PLoS One 4(10):e7502, 2009. e-Pub 2009. PMID: 19847298.
Liang JJ, Wang H, Rashid A, Tan TH, Hwang RF, Hamilton SR, Abbruzzese JL, Evans DB, Wang H. Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma. Clin Cancer Res 14(21):7043-7049, 2008. e-Pub 2008. PMID: 18981001.
Yi M, Krishnamurthy S, Kuerer HM, Meric-Bernstam F, Bedrosian I, Ross MI, Ames FC, Lucci A, Hwang RF, Hunt KK. Role of primary tumor characteristics in predicting positive sentinel lymph nodes in ductal carcinoma in situ or microinvasive breast cancer. Am J Surg 196(1):81-87, 2008. e-Pub 2008. PMID: 18436181.
Yi M, Meric-Bernstam F, Ross MI, Akins JS, Hwang RF, Lucci A, Kuerer HM, Babiera GV, Gilcrease MZ, Hunt KK. How many sentinel lymph nodes are enough during sentinel lymph node dissection for breast cancer?. Cancer 113(1):30-37, 2008. e-Pub 2008. PMID: 18457326.
Hwang RF, Wang H, Lara A, Gomez H, Chang T, Sieffert N, Moon Y, Ram S, Zimmerman S, Lee JH, Pisters PW, Tamm EP, Fleming JB, Abbruzzese JL, Evans DB. Development of an integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer. Ann Surg Oncol 15(5):1356-1366, 2008. e-Pub 2008. PMID: 18256882.
Katz MH, Pisters PW, Evans DB, Sun CC, Lee JE, Fleming JB, Vauthey JN, Abdalla EK, Crane CH, Wolff RA, Varadhachary GR, Hwang RF. Borderline resectable pancreatic cancer: the importance of this emerging stage of disease. J Am Coll Surg 206(5):833-846, 2008. e-Pub 2008. PMID: 18471707.
Khalifeh IM, Albarracin C, Diaz LK, Symmans FW, Edgerton ME, Hwang RF, Sneige N. Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma. Am J Surg Pathol 32(4):544-552, 2008. e-Pub 2008. PMID: 18300793.
Hwang RF, Moore T, Arumugam T, Ramachandran V, Amos KD, Rivera A, Ji B, Evans DB, Logsdon CD. Cancer-associated stromal fibroblasts promote pancreatic tumor progression. (Highlighted Article). Cancer Res 68(3):918-926, 2008. e-Pub 2008. PMID: 18245495.
Hwang RF, Gonzalez-Angulo AM, Yi M, Buchholz TA, Meric-Bernstam F, Kuerer HM, Babiera GV, Tereffe W, Liu DD, Hunt KK. Low local-regional failure rates in selected breast cancer patients with tumor-positive sentinel nodes who do not undergo completion axillary dissection. Cancer 110(4):723-730, 2007. e-Pub 2007. PMID: 17587208.
Ramachandran V, Arumugam T, Hwang RF, Greenson JK, Simeone DM, Logsdon CD. Adrenomedullin is expressed in pancreatic cancer and stimulates cell proliferation and invasion in an autocrine manner via the adrenomedullin receptor (ADMR). Cancer Res 67(6):2666-2675, 2007. e-Pub 2007. PMID: 17363587.
Baruch AC, Wang H, Staerkel GA, Evans DB, Hwang RF, Krishnamurthy S. Immunocytochemical study of the expression of mesothelin in fine-needle aspiration biopsy specimens of pancreatic adenocarcinoma. Diagn Cytopathol 35(3):143-147, 2007. e-Pub 2007. PMID: 17304533.
Raut CP, Tseng JF, Sun CC, Cleary KR, Wang H, Wolff RA, Abbruzzese JF, Varadhachary G, Tamm EP, Crane CH, Gomez HF, Hwang RF, Vauthey JN, Abdalla EK, Lee JE, Pisters PWT, Evans DB. Impact of resection status on pattern of failure and survival after pancreaticoduodenectomy for pancreatic adenocarcinoma. Ann Surg 246(1):52-60, 2007. e-Pub 2007. PMID: 17592291.
Boughey JC, Ross MI, Babiera GV, Bedrosian I, Feig BW, Hwang RF, Kuerer HM, Hunt KK. Sentinel lymph node surgery in locally recurrent breast cancer. Clin Breast Cancer 7(3):248-253, 2006. e-Pub 2006. PMID: 16942642.
Lambert LA, Ayers GD, Hwang RF, Hunt KK, Ross MI, Kuerer HM, Singletary SE, Babiera GV, Ames FC, Feig B, Lucci A, Krishnamurthy S, Meric-Bernstam F. Validation of a breast cancer nomogram for predicting nonsentinel lymph node metastases after a positive sentinel node biopsy. Ann Surg Oncol 13(3):310-320, 2006. e-Pub 2006. PMID: 16463073.
Rosenkranz KM, Bedrosian I, Feng L, Hunt KK, Hartman K, Lucci A, Meric-Bernstam F, Kuerer HM, Singletary ES, Hwang RF, Feig B, Ross M, Ames F, Babiera GV. Breast cancer in the very elderly: treatment patterns and complications in a tertiary cancer center. Am J Surg 192(4):541-544, 2006. e-Pub 2006. PMID: 16978971.
Garmy-Susini B, Jin H, Zhu Y, Sung RJ, Hwang RF, Varner J. Integrin alpha4beta1-VCAM-1-mediated adhesion between endothelial and mural cells is required for blood vessel maturation. J Clin Invest 115(6):1542-1551, 2005. e-Pub 2005. PMID: 15902308.
Parker B, Garmy-Susini B, Jin H, Zhu Y, Sung R, Hwang RF. Clues to targeting integrin-VCAM interactions in tumor angiogenesis. Cancer Biology and Therapy 4(6):618, 2005. e-Pub 2005.
Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ. Inhibition of platelet-derived growth factor reception phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. (Cover Article). Clin Cancer Res 9(17):6534-6544, 2003. e-Pub 2003. PMID: 14695158.
Solorzano CC, Hwang RF, Baker CH, Bucana CD, Pisters PW, Evans DB, Killion JJ, Fidler IJ. Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. Clin Cancer Res 9(5):1858-1867, 2003. e-Pub 2003. PMID: 12738744.
Hwang RF, Krishnamurthy S, Hunt KK, Mirza N, Ames FC, Feig B, Kuerer HM, Singletary SE, Babiera G, Meric F, Akins JS, Neely J, Ross MI. Clinicopathologic factors predicting involvement of nonsentinel axillary nodes in women with breast cancer. Ann Surg Oncol 10(3):248-254, 2003. e-Pub 2003. PMID: 12679309.
Hwang RF, Gordon EM, Anderson WF, Parekh D. Gene therapy for primary and metastatic pancreatic cancer with intraperitoneal retroviral vector bearing the wild-type p53 gene. Surgery 124(2):143-150; discussion 150-151, 1998. e-Pub 1998. PMID: 9706132.
Yang L, Hwang RF, Chiang Y, Gordon EM, Anderson WF, Parekh D. Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex thymidine kinase gene. Clin Cancer Res 4(3):731-741, 1998. e-Pub 1998. PMID: 9533543.
Yang L, Hwang RF, Pandit L, Gordon EM, Anderson WF, Parekh D. Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir. Ann Surg 224(3):405-414; discussion 414-417, 1996. e-Pub 1996. PMID: 8813269.
Mizuno T, Cloyd JM, Omichi K, Okuno M, Yamashita S, Lillemoe HA, Chun YS, Conrad C, Tzeng CW, Wei SH, Thomas A, Ueno N, Valero V, Giordano SH, Kuerer HM, Hunt KK, Bedrosian I, Caudle AS, Hwang RF, Meric- Bernstam F, Vauthey JN, Barcenas CB. Association between systemic therapy followed by hepatic resection and overall survival in patients with isolated breast cancer liver metastases. Journal of Clinical Oncology.
Murthy D, Attri K, Shukla S, Chaika N, Wang D, Thakur R, Dasgupta A, King R, He C, Mulder S, Souchek J, Gebregiworgis T, Rai V, Rana S, Kollala S, Pacheco C, Grandgenett P, Yu F, Kumar V, Lazenby A, Black A, Klinkebiel D, Powers R, Natarajan A, Hollingsworth M, Mehla K, Ly Q, Hwang R, Wellen KE, Singh P. Selective Dependence on Stromal Acetate-induced Polyamine Metabolism Provides Unique Therapeutic Opportunities in Pancreatic Cancer. Nature Cell Biology.

Invited Articles

Fornage BD, Hwang RF. Current status of imaging-guided percutaneous ablation of breast cancer. AJR Am J Roentgenol 203(2):442-8, 2014. e-Pub 2014. PMID: 25055283.
Hwang RF. Commentary on: Novel factors to improve prediction of nodal positivity in patients with clinical T1/T2 breast cancers. Breast Diseases: A Year Book Quarterly 25(2):137-138, 2014. e-Pub 2014.
Hwang RF. Commentary on: A simple nomogram to evaluate the risk of nonsentinel node metastases in breast cancer patients with minimal sentinel node involvement. Breast Diseases: A Year Book Quarterly 23(3):260-261, 2012. e-Pub 2012.
Sharma R, Wagner JL, Hwang RF. Ablative therapies of the breast. Surg Oncol Clin N Am 20(2):317-339, 2011. e-Pub 2011. PMID: 21377586.
Hwang RF. Commentary on: Axillary recurrence is low in patients with breast cancer who do not undergo completion axillary lymph node dissection for micrometastases in sentinel lymph nodes. Am Surg 76:1088-1091, 2010. Breast Diseases: A Year Book Quarterly 22(4):396-397, 2011. e-Pub 2011.
Hwang RF, Giuliano A, Sahin A, Feldman S, Van Zee K. Regional management of breast cancer: Highlights from the 11th Annual Meeting of the American Society of Breast Surgeons, Las Vegas, NV. Ann Surg Oncol 17(Suppl 3):S226-S229, 2010. e-Pub 2010. PMID: 20853037.
Hwang RF. Commentary on: Predictors to assess non-sentinel lymph node status in breast cancer patients with sentinel lymph node metastasis. Breast Diseases: A Year Book Quarterly 20(4):417, 2010. e-Pub 2010.
Hwang RF. Commentary on: Validation of a nomogram to predict the risk of nonsentinel lymph node metastases in breast cancer patients with a positive sentinel node biopsy: validation of the MSKCC breast nomogram. Breast Diseases: A Year Book Quarterly 21(1):58, 2010. e-Pub 2010.
Hwang RF. Commentary on: Nomogram for the predicting of having four or more involved nodes for sentinel lymph node-positive breast cancer. Breast Diseases: A Year Book Quarterly 20(1):68, 2009. e-Pub 2009.
Hwang RF. Commentary on: Evaluation of a breast cancer nomogram for prediction of nonsentinel lymph node positivity. Eur J Surg Oncol 31:958-964, 2005. Breast Diseases: A Year Book Quarterly 17:380-381, 2007. e-Pub 2007.
Hwang RF. Commentary on: The incidence and significance of micrometastases in lymph nodes of patients with ductal carcinoma in situ and T1a carcinoma of the breast. Eur J Surg Oncol 32:502-506, 2006. Breast Diseases: A Year Book Quarterly 18:80, 2007. e-Pub 2007.
Hwang RF. Commentary on: Differences in sentinel lymph node pathology protocols lead to differences in surgical strategy in breast cancer patients. Ann Surg Oncol 2006; 13: 1466-1473. Breast Diseases: A Year Book Quarterly 18:382, 2007. e-Pub 2007.
Hwang RF. Commentary on: The significance of one positive axillary node. Eur J Surg Oncol 32:139-142, 2006. Breast Diseases: A Year Book Quarterly 17:383-384, 2007. e-Pub 2007.
Hwang RF. Commentary on: Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer. Breast J 11:338-343, 2005. Breast Diseases: A Year Book Quarterly 17:174, 2006. e-Pub 2006.
Hwang RF. Commentary on: Ratio on positive to total number of sentinel nodes predicts nonsentinel node status in breast cancer patients. Breast J 11:248-253, 2005. Breast Diseases: A Year Book Quarterly 17:74-75, 2006. e-Pub 2006.
Hwang RF. Commentary on: The impact of nonvisualization of sentinel nodes of lymphoscintigraphy in breast cancer. Ann Surg Oncol 7:1-6, 2005. Breast Diseases: A Year Book Quarterly 17:79, 2006. e-Pub 2006.
Hwang RF. Commentary on: The effect of sentinel node tumor burden on nonsentinel node status and recurrence rates in breast cancer. Ann Surg Oncol 12:705-711, 2005. Breast Diseases: A Year Book Quarterly 17:171, 2006. e-Pub 2006.
Hwang RF, Evans DB. CA19-9 and CA 125 markers in the differential diagnosis of pancreatic mass lesions. Arch Surg 141:974, 2006. e-Pub 2006.
Hwang RF, Varner J. The role of integrins in tumor angiogenesis. Hematol Oncol Clin North Am 18(5):991-1006, 2004. e-Pub 2004. PMID: 15474331.
Hwang RF. Commentary on: Extracapsular extension of the sentinel lymph node metastasis: a predictor of nonsentinel node tumor burden. Ann Surg 2003; 237: 607-613. Breast Diseases: A Year Book Quarterly 15:66-67, 2004. e-Pub 2004.
Hwang RF, Hunt K. Experimental approaches to soft tissue sarcoma. Surgical Oncology Clinics of North America 12(2):499-521, 2003. e-Pub 2003. PMID: 12916466.

Review Articles

Chu CK, Hanson SE, Hwang RF, Wu LC. Oncoplastic partial breast reconstruction: concepts and techniques. Gland Surg 10(1):398-410, 2021. e-Pub 2021. PMID: 33633998.
Hanson SE, Kapur SK, Hwang RF, Dryden MS. Autologous fat grafting in breast reconstruction: implications for follow-up and surveillance. Gland Surg 10(1):487-493, 2021. e-Pub 2021. PMID: 33634006.
Van Leeuwen BL, Rosenkranz KM, Feng LL, Bedrosian I, Hartmann K, Hunt KK, Kuerer HM, Ross M, Singletary SE, Babiera GV, Surgical Oncology DO, MD Anderson Cancer Center - Collaborators: Feig B, Ames F, Hwang RF, Lucci A, Meric-Bernstam F. The effect of under-treatment of breast cancer in women 80 years of age and older. Crit Rev Oncol Hematol 79(3):315-20, 2011. e-Pub 2011. PMID: 20655242.
Katz MH, Mortenson MM, Wang H, Hwang RF, Tamm EP, Staerkel G, Lee JH, Evans DB, Fleming JB. Diagnosis and management of cystic neoplasms of the pancreas: an evidence-based approach. J Am Coll Surg 207(1):106-120, 2008. e-Pub 2008. PMID: 18589369.
Katz MH, Hwang RF, Fleming JB, Evans DB. Tumor-node-metastasis staging of pancreatic adenocarcinoma. CA Cancer J Clin 58(2):111-125, 2008. e-Pub 2008. PMID: 18272835.
Hwang RF, Hunt KK. Experimental approaches to treatment of soft tissue sarcoma. Surg Oncol Clin N Am 12(2):499-521, 2003. e-Pub 2003. PMID: 12916466.

Professional Educational Materials

Hwang RF, Oates S. Skin-Sparing Mastectomy with Immediate Free-TRAM Reconstruction; Video Clip for "Kuerer's Breast Surgical Oncology". McGraw-Hill Professional, 2010.
Song S, RF| MD. Galectin-3 Mediates Tumor-stromal interactions by activating Pancreatic Stellate Cell and promoting Cytokine/Chemokine production. Gastroenterology Editorial Office.

Editorials

Yi M, Kuerer H, Mittendorf EA, Hwang RF, Caudle AS, Bedrosian I, Meric-Bernstam F, Wagner JL, Hunt KK. Impact of the American College of Surgeons Oncology Group Z0011 criteria applied to a contemporary patient population. J Am Coll Surg 216(1):105-13, 2013. PMID: 23122536.

Abstracts

Hwang RF. Cost and complication burden of oncoplastic breast conservation compared to other treatment options in women with breast cancer. The American Society of Breast Surgeons, 2017. e-Pub 2017.
Kuerer H, Tadros A, Hwang RF. Eliminating Axillary Surgery in Exceptional Responders to Neoadjuvant Chemotherapy (NCT) with Documented Pathologic Complete Response in the Breast. Oral Presentation at the Society of Surgical Oncology Meeting (SSO), 2017. e-Pub 2017.
Srinivasan A, Fornage B, Sneige N, Hwang RF, Huong L. Breast Ablative Therapy: Back to the Future. Oral Presentation, SBI/ACR Breast Imaging Symposium 2016, Austin, TX, 2016. e-Pub 2016.
Oluwadamilola FM, Mayo TL, Spinks TE, LeeS, Barcenas CB, Smith BD, Giordano SG, Hwang RF, Ehlers RA, Selber JC, Walters RC, Tripathy D, Hunt KK, Thomas AB, Feeley TW, Henry KM. Implementing Value-Based Cancer Care: A Multidisciplinary Approach to Defining Breast Cancer Outcomes. 2016 ASCO Quality Care Symposium, 2016. e-Pub 2016.
Ross MI, Bedrosian I, Black DM, Mittendorf EA, Caudle AS, Babiera GV, Hwang RF, Meric-Bernstam F, Grissom CB, Brulotte M, Andtbacka RHI. A phase I clinical trial of VST-1001 (dilute fluorescein) in lymphatic mapping and sentinel lymph node localization in clinically node negative breast cancer, Poster Presentation;San Antonio Breast Cancer Symposium 2015, 2015. e-Pub 2015.
Simmons R, Ballman K, Cox C, Carp N, Sabol J, Hwang RF, Attai D, Sabel M, Nathanson D, Kenler A, Gold L, Kaufman C, Han L, Bleznak A, Smith JS, Holmes D, Tafra L, Dudak M, Weinberg S, Kinney M, Le-Petross C, Hoda S, Buchholz T, Cormier J, Lindeman W, McCall L, Watson M, GreenB, Hunt K. A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072. Oral presentation at the American Society of Breast Surgeons 15th Annual Meeting, 2014. e-Pub 2014.
Munoz AR, Gong J, Chakravarthy D, Hwang RF, Payton-Stewart F, Chan DE, Freeman JW, Ghosh R, Kumar AP. Targeting the STAT3/NF-kB signaling axis through combination treatment with nexrutine & gemcitabine for pancreatic cancer. Oral Presentation, American Association for Cancer Research (AACR) Special Conference on: Pancreatic Cancer: Innovations in Research and Treatment, New Orleans, LA, 2014. e-Pub 2014.
Shen MC, Bloom E, Shaitelman SF, Wei C, Haynes AB, Mittendorf EA, Kuerer HM, Bedrosian I, Hwang RF, Hunt KK, Tereffe W, Strom E, Babiera GV. Comparison of infectious complications between breast conserving therapy with cathetered-based accelerated partial irradiation and whole breast irradiation. Poster Presentation, 36th Annual San Antonio Breast Cancer Symposium (SABCS), San Antonio, TX, 2013. e-Pub 2013.
Principe DR, Bauer J, Mascarinas W, Hwang RF, Jung B, Grippo PJ. Therapeutic implications of compartmental TGFb signaling. Poster Presentation, 44th Annual Meeting of the American Pancreatic Association (APA), Miami, FL, 2013. e-Pub 2013.
FitzSullivan E, Kuerer HM, Bassett RL, Mittendorf EA, Yi M, Hunt K, Babiera G, Caudle AS, Black DM, Bedrosian I, Meric-Bernstam F, Hwang RF. Outcomes of sentinel lymph node-positive breast cancer patients treated with mastectomy with axillary therapy. Poster Presentation, American Society of Clinical Oncology (ASCO) Breast Cancer Symposium, San Francisco, CA. J Clin Oncol 31(26 Suppl (Sep. 10 Suppl)):53, 2013. e-Pub 2013.
Chakravarthy D, Gong J, Kumar AP, Hwang RF. Targeting pancreatic cancer stroma with Palmatine, a novel compound from herbal supplement. Poster Presentation, Annual Meeting of the American Association for Cancer Research (AACR), Washington, DC, 2013. e-Pub 2013.
Gonzalez-Villasana V, Rodriguez-Aguayo C, Arumugam T, Cruz-Monserrate Z, Deng D, Funentes-Mattei E, Hwang RF, Wang H, Pena Armaiz GN, Aslan B, Gutierrez-Puente Y, Sood AK, Logsdon C, Lopez-Berestein G. Targeting pancreatic stellate cells (PSC) to treat pancreatic cancer. Poster Presentation, Annual Meeting of the American Association for Cancer Research (AACR) Washington, DC, 2013. e-Pub 2013.
FitzSullivan E, Lari SA, Smith B, Caudel AS, Krishnamurthy S, Lucci A, Mittendorf EA, Babiera G, Black S, Wagner JL, Bedrosian I, Woodward W, Gainer SM, Hwang RF, Meric-Bernstam F, Hunt K, Kuerer HM. Incidence and consequence of close margins for ductal carcinoma in situ treated with mastectomy. Oral Presentation, 66th Annual Society of Surgical Oncology (SSO) Cancer Symposium, National Harbor, MD, Ann Surg Oncol 20(1 Suppl):S9, 2013. e-Pub 2013.
Haynes AB, Bloom ES, Bedrosian I, Kuerer HM, Hwang RF, Caudle AS, Hunt KK, Tereffe W, Shaitelman SF, Babiera GV. Timing of infectious complications following breast conserving therapy using catheter-based accelerated partial breast irradiation. Poster Presentation, 35th Annual San Antonio Breast Cancer Symposium (SABCS) Meeting, San Antonio, TX, 2012. e-Pub 2012.
Hwang RF, Moore T, Mertens Hattersley M, Scarpitti M, Yang B, Devereaux E, Ramachandran V, Arumugam T, Ji B, Logsdon CD, Brown JL, Godin R. Hedgehog signaling in pancreatic cancer is dependent on stellate cells in a paracrine fashion, Oral Presentation, American Pancreatic Association (APA)/International Association of Pancreatology (IAP) Joint Annual Meeting, Miami, FL. Pancreas 41(8):1368, 2012. e-Pub 2012.
Charo C, Holla V, Arumugam T, Hwang RF, Yang P, Dubois RN, Menter DG, Logsdon CD, Ramachandran V. PGE2 regulates pancreatic stellate cell activity via the EP4 receptor, American Pancreatic Association (APA)/International Association of Pancreatology (IAP) Joint Annual Meeting, Miami, FL. Pancreas 41(8):1352, 2012. e-Pub 2012.
Arumugam T, Fujii T, Haojie H, Hwang RF, Ramachandran V, Logsdon CD. Interleukin-8 (IL-8) expression is a surrogate marker for effects of gemcitabine on pancreatic ductal adenocarcinoma (PDAC) cells, American Pancreatic Association (APA)/International Association of Pancreatology Annual Meeting, Miami, FL. Pancreas 41(8):1347, 2012. e-Pub 2012.
Allen LR, Gadgil PV, Bassett Jr R, Hunt K, Mittendorf EA, Yi M, Babiera G, Kuerer HM, Ross MI, Bedrosian I, Meric-Bernstam F, Hwang RF. Nomogram to predict sentinel lymph node involvement in patients with clinically node-negative breast cancer receiving neoadjuvant chemotherapy. Poster Discussion Session, American Society of Clinical Oncology (ASCO) Breast Cancer Symposium, San Francisco, CA. J Clin Oncol 30(27 Suppl):150, 2012. e-Pub 2012.
Yi M, Mittendorf EA, Hwang RF, Babiera GV, Kuerer HM, Crow J, Lange R, Shah R, Hunt K. Are mastectomy rates really increasing? Experiences from a single institution and a population-based database. Poster Presentation, American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago, IL, 2012. e-Pub 2012.
Yi M, Le-Petross H, Gilcrease M, Mittendorf EA, Bedrosian I, Meric-Bernstam F, Hwang RF, Caudle AS, Akins JS, Kuerer HM, Hunt KK. Is sentinel lymph node biopsy accurate after neoadjuvant chemotherapy in patients who present with node positive breast cancer?. Poster Presentation, American Society of Breast Surgeons' 13th Annual Meeting (ASBS), Phoenix, AZ, 2012. e-Pub 2012.
Akay C, Whitsell T, Albarracin C, Hunt KK, Bassett R, Mittendorf EA, Yi M, Sahin A, Krishnamurthy, Kuerer H, Meric-Bernstam F, Babiera GV, Bedrosian I, Hwang RF. Intraoperative sentinel lymph node evaluation is accurate after neoadjuvant therapy for breast cancer. Poster Presentation, 65th Annual Cancer Symposium Society of Surgical Oncology (SSO), Orlando, FL. Ann Surg Oncol 19(Suppl 1):S86, 2012. e-Pub 2012.
Alvarado R, Lari SA, Roses RE, Smith BD, Yang W, Mittendorf EA, Arun BK, Lucci A, Babiera GV, Wagner JL, Caudle AS, Meric-Bernstam F, Hwang RF, Bedorsian I, Hunt KK, Kuerer HM. Biology, treatment, and outcome in very young and older women with DCIS. Poster Presentation, 65th Annual Cancer Symposium Society of Surgical Oncology (SSO), Orlando, FL. Ann Surg Oncol 19(Suppl 1):S58, 2012. e-Pub 2012.
Hwang RF. Blocking tumor-stromal interactions in pancreatic cancer by targeting stromal cell-derived Dickkopf-3 (DKK3). Poster Presentation, 7th Annual Academic Surgical Congress, Las Vegas, NV, 2012. e-Pub 2012.
Gainer SM, Mittendorf EA, Hunt KK, Bassett RL, Yi M, Meric-Bernstam F, Ross MI, Babiera GV, Kuerer HM, Caudle AS, Hwang RF. Nomogram incorporating SLN metastasis size provides the most accurate prediction of non-SLN involvement in breast cancer patients. Poster Presentation, 34th Annual Meeting San Antonio Breast Cancer Symposium (SABCS), San Antonio, TX. Cancer Res 71(Suppl 24):39S, 2011. e-Pub 2011.
Veerapong J, Boughey J, Mittendorf E, Harrell R, Bassett R, Ross M, Yi M, Meric-Bernstam F, Babiera G, Kuerer H, Lucci A, Bedrosian I, Brodt J, Jakub J, Hunt K, Hwang RF. A validated risk assessment of sentinel lymph node involvement in breast cancer patients. Poster Presentation, 64th Annual Society of Surgical Oncology Cancer Symposium (SSO), San Antonio, TX. Ann Surg Oncol 18(Suppl 1):S59, 2011. e-Pub 2011.
Abdel-Rahman S, Le-Petross H, Whitman GJ, Meric-Bernstam F, Babiera GV, Hunt KK, Hwang RF, Lucci A, Feig BW, Ross MI, Mittendorf EA, Kuerer HM, Bedrosian I. Prospective study to evaluate surgical impact and cost of routine preoperative breast MRI in women with invasive lobular carcinoma. Oral Presentation, 64th Annual Cancer Symposium Society of Surgical Oncology (SSO), San Antonio, TX. Ann Surg Oncol 18(Suppl 1):S16, 2011. e-Pub 2011.
Mittendorf EA, Boughey JC, Degnim AC, Harrell R, Bassett R, Yi M, Meric-Bernstam F, Ross MI, Babiera GV, Kuerer HM, Lucci A, Bedrosian I, Hunt KK, Hwang RF. Size matters: incorporation of sentinel lymph node (SLN) metastasis size into a nomogram predicting non SLN involvement in SLN positive breast cancer patients. 33rd. Annual San Antonio Breast Cancer Symposium (SABCS), San Antonio, TX. Cancer Res 70(24 Suppl; PD06-08):117S, 2010. e-Pub 2010.
Husted H, Moore T, Deng D, Ramachandran V, Arumugam T, Logsdon CD, Hwang RF. Stellate cell-derived Dickkopf-3 (DKK3) induces PDAC tumor progression and chemoreistance. Oral Presentation, 41st. Annual Meeting of the American Pancreatic Association, Chicago, IL. Pancreas 39(8):1324, 2010. e-Pub 2010.
Yi M, Meric-Bernstam F, Kuerer HM, Hwang RF, Bedrosian I, Mittendorf EA, Rourke L, Hunt KK. Role of completion axillary lymph node dissection of sentinel node-positive cancer patients. Oral and Poster Presentation, 11th Annual Meeting of the American Society of Breast Surgeons (ASBS), Las Vegas, NV, 2010. e-Pub 2010.
Ranjna S, Bedrosian I, Lucci A, Hwang RF, Rourke LL, Buchholz TA, Qiao W, Meric-Bernstam F, Gonzalez-Angula AM, Kronowitz SJ, Babiera GV, Mittendorf EA, Krishnamurthy S, Hunt KK, Kuerer HM. Present day local-regional recurrence rates (LRR) in patients with TI and T2 breast cancer (BC) with 0 and 1 to 3 lymph node (LN) metastases following mastectomy without radiation. Ann Surg Oncol 17(Suppl 1)(S20), 2010. e-Pub 2010.
Hwang RF, Rivera A, Husted H, Moore T, Ramachandran V, Arumugam T, Ji B, Logsdon CD. Targeting periostin in the tumor-associated stroma of pancreatic cancer. Oral Presentation, 5th Annual Academic Surgical Congress (ASC), San Antonio, TX, 2010. e-Pub 2010.
Husted H, Moore T, Ji B, Ramachandran V, Arumugam T, Logsdon CD, Hwang RF. Pancreatic stellate cells secrete the WNT inhibitor DKK3. Oral Presentation, 40th Anniversary Meeting of the American Pancreatic Association (APA) and Japan Pancreas Society, Honolulu, HI, 2009. e-Pub 2009.
Hwang RF, Evans DB, Coombes K, Logsdon CD. Gene expression profiling of pancreatic adenocarcinoma after neoadjuvant chemoradiation identifies potential markers of outcome. Poster Presentation, The American Association for Cancer Research (AACR), Denver, CO, 2009. e-Pub 2009.
Hwang RF, Moore T, Rivera A, Evans DB, Logsdon CB. Expression profile of pancreatic cancer-associated fibroblasts is distinct from carcinoma cells. Oral Presentation, 62nd. Annual Society of Surgical Oncology Cancer Symposium (SSO), Phoenix, AZ, 2009. e-Pub 2009.
Kong AL, Hunt KK, Warneke CL, Hwang RF, Meric-Bernstam F, Bedrosian I, Yi M, Ross MI, Babiera GV, Mittendorf EA. Sentinel node dissection (SLND) is technically feasible and accurate in older breast cancer patients. Poster Presentation, Ann Surg Oncol 16(12), 2009. e-Pub 2009.
Hwang RF, Moore T, Ramachandran V, Arumugam R, Rivera A, Logsdon CD. Pancreatic cancer-associated fibroblasts promote angiogenesis in vitro and in vivo. Oral Presentation, Gastrointestinal Cancers Symposium, San Francisco, CA, 2009. e-Pub 2009.
Rivera A, Moore T, Ramachandran V, Arumugam T, Logsdon CD, Hwang RF. Tumor-associated pancreatic stellate cells stimulate angiogenesis in vitro and in an orthotopic model of pancreatic cancer. Oral Presentation, American Pancreatic Association (APA), Chicago, IL, 2008. e-Pub 2008.
Bose D, Tamm E, Liu J, Kesmodel S, Lee JH, Gomez H, Fleming J, Evans DB, Hwang RF. Incidental cystic lesions of the pancrease: multidisciplinary management of 350 patients. Oral Presentation, 94th Annual Clinical Congress American College of Surgeons (ACS), San Francisco, CA, 2008. e-Pub 2008.
Kong AL, Hunt KK, Yi M, Weatherspoon K, Bedrosian I, Tereffe W, Hwang RF, Ross MI, Buchholz TA, Meric-Bernstam F. The impact of IMC nodal drainage on primary breast cancer outcome. Poster Presentation, American Society of Clinical Oncology (ASCO), Chicago, IL, 2008. e-Pub 2008.
Yi M, Meric-Bernstam F, Middleton LP, Arun BK, Bedrosian I, Babiera G, Hwang RF, Feig BW, Kuerer HM, Lucci A, Ross MI, Hunt KK. Predictors of contralateral breast cancer in patients with unilateral breast cancer. Poster Presentation, American Society of Breast Surgeons (ASBS), New York City, NY, 2008. e-Pub 2008.
Hwang RF. An integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer, 2nd Annual Academic Surgical Congress, Oral Presentation, Phoenix, AZ, 2007. e-Pub 2007.
Hwang RF, Moore T, Amos KD, Arumugam T, Ramachandran V, Logsdon C. Effect of pancreatic tumor-associated stellate cells on pancreatic tumor growth, metastasis and angiogenesis. Poster Presentation, 98th Annual Meeting of the American Association for Cancer Research (AACR), Los Angeles, CA, 2007. e-Pub 2007.
Katz MH, Wolff RA, Pisters PW, Sun CC, Evans DB, Varadhachary GR, Fleming JB, Hwang RF. Borderline resectable pancreatic cancer: the importance of this emerging stage of disease. Oral Presentation, Southern Surgical Association (SSA) Meeting, Hot Springs, VA, 2007. e-Pub 2007.
Arumugam T, Hwang RF, Moore TT, Wang H, Brandt W, Westley BR, Logsdon C. TFF1 is overexpressed early in pancreatic cancer and stimulates cancer cell invasion and stromal cell growth and migration. Oral Presentation, International Society of Gastrointestinal Oncology, Philadelphia, PA, 2007. e-Pub 2007.
Arumugam T, Hwang RF, Moore T, Wang H, Brandt W, Westley B, Logsdon C. TFF1 is over expressed early in pancreatic cancer in response to cancer-stromal interactions and stimulates cancer cell invasiveness. Poster Presentation, 98th Annual Meeting of the American Association for Cancer Research (AACR), Los Angeles, CA, 2007. e-Pub 2007.
Yi M, Hunt KK, Meric-Bernstam F, Bedrosian I, Hwang RF, Kuerer HM, Lucci A, Ross MI, Akins J, Babiera GV. Sentinel lymph node biopsy in patients with multicentric invasive breast cancer. Poster Presentation, American Society of Clinical Oncology (ASCO) Breast Meeting, San Francisco, CA, 2007. e-Pub 2007.
Rosenkranz KM, Hartman K, Ghonimi E, Kuerer HM, Singletary SE, Hunt KK, Meric-Bernstam F, Lucci A, Hwang RF, Feig B, Ross MI, Ames F, Babiera GV. Breast cancer in the very elderly: treatment patterns in a comprehensive cancer center, American Society of Breast Surgeons, Poster Presentation, Baltimore, MD, 2006. e-Pub 2006.
Killary AM, Frazier M, Lott S, Carter J, Stivers D, Chen J, Hwang RF, Abbruzzese J, Sens S. A functional genomic approach to biomarker discovery in pancreatic cancer, Presented as a Poster, NCI, Early Detection Research Network Steering Committee Meeting, Philadelphia, PA, 2006. e-Pub 2006.
Amos KD, Moore T, Arumugam T, Logsdon CD, Hwang RF. Pancreatic stellate cells promote malignant potential in pancreatic cancer, In: Proceedings of the 97th Annual Meeting of the American Association for Cancer Research; 2006 Apr 1-5; Washington, DC: AACR: Abstract 1679, 2006. e-Pub 2006.
Boughey JC, Khakpour N, Meric-Bernstam F, Ross MI, Hwang RF, Babiera GV. The routine use of sentinel lymph node surgery in prophylactic mastectomy is not warranted. Ann Surg Oncol 13:P64, 2006. e-Pub 2006.
Yi M, Meric-Bernstam F, Akins JS, Hwang RF, Lucci A, Babiera GV, Hunt KK. How many sentinel lymph nodes are enough during sentinel lymph node dissection for breast cancer?, 29th Annual San Antonio Breast Cancer Symposium, Poster Presentation, (Abstract # 2013). Breast Cancer Res Treat 100:S84, 2006. e-Pub 2006.
Tereffe W, Buchholz TA, Oh JL, Perkins GH, Strom EA, Woodward WA, Yu TK, Hunt KK, Hwang RF. Radiotherapy targeting of regional nodes in sentinel lymph node-positive breast cancer patients who do not undergo axillary dissection, 29th Annual San Antonio Breast Cancer Symposium, Oral Presentation, (Abstract # 4086). Breast Cancer Res Treat 100:S200, 2006. e-Pub 2006.
Hwang RF, Bucana C, Killion J, Evans D, Fidler IJ. Targeted therapy of human pancreatic cancer with STI571 (Gleevec) in an orthotopic nude mouse model. Ann Surg Onc 1:S23, 2003. e-Pub 2003.
Hwang RF, Bucana C, Killion J, Evans DB, Fidler IJ. Targeted therapy of human pancreatic cancer with RPR127963E, a novel inhibitor of platelet-derived growth factor receptor, in an orthotopic nude mouse model. J Am Coll Surgeons 195:S7, 2002. e-Pub 2002.
Gonzalez A, Gardner C, Mohite S, Sun J, Hwang RF, Bhosale P, Katz M, Qayyum A. Borderline Resectable Pancreatic Adenocarcinoma: Tumor Enhancement and Prognosis. Society of Abdominal Radiology.
Hwang RF. Borderline Resectable Pancreatic Adenocarcinoma: Tumor Enhancement and Prognosis. Society of Abdominal Radiology.
Hwang RF, Kopkash K, Piltin M, Jakub J, Aft R, Amersi F, Brooks A, Chiba A, Chung A, Elmore L, Farley C, Flanagan M, Hwang S, Javid S, Johnson J, Kadison A, Lal A, McCarty S, Rand J, Tseng J. Robotic-assisted nipple sparing mastectomy: multi-center clinical trials in progress in the U.S. SSO 2026 Annual Meeting.

Book Chapters

Moscol, G, Mitchell, MP, Hwang, RF. Breast Cancer, 227-257, 2024.
Burns HR, McCarter JH, King BW, Yu JZ, Hwang RF. Robotic-Assisted Nipple Sparing Mastectomy. In: Semin Plast Surg. 3, 176-183, 2023.
Hwang RF. Stromal Barriers to Delivery. In: Mass Transport of Nanocarriers. Pan Stanford Publishing Pte. Ltd, 83-95, 2013.
Fleming JB, Katz MHG, Hwang RF, Varadhachary GR. Pancreatic Cancer. In: 60 Years of Survival Outcomes at the University of Texas, M. D. Anderson Cancer Center. Springer, 119-132, 2013.
Bowels TL, Amos KD, Hwang RF, Fleming JB. Small Bowel Malignancies and Carcinoid Tumors. In: The M.D. Anderson Surgical Oncology Handbook, 5th Ed. 5th Edition. Wolters Kluwer, Lippincott Williams & Wilkins, 323-346, 2012.
Akay CL, Kuerer HM, Hwang RF. Sentinel Lymph Node Biopsy in Breast Cancer: The MD Anderson Cancer Center Approach. In: Advanced Therapy of Breast Disease, 3rd. Edition. 3rd. Edition. People's Medical Publishing House, 545-555, 2012.
Kong A, Hwang RF. Sentinel Lymph Node Biopsy: An Overview. In: Breast Medical Techniques and Interdisciplinary Management. Springer, 471-480, 2011.
Logsdon C, Ji B, Hwang RF. Novel Molecular Relationships Between Chronic Pancreatitis and Pancreatic Cancer. In: Handbook of Pancreatic Cancer. Springer, 285-315, 2009.
Hwang RF, Ross MI. Treatment Options and Surgical Techniques for Early-Stage Breast Cancer. In: Advanced Therapy in Surgical Oncology. 1. B.C. Decker, 489-501, 2007.
Hwang RF, Grau AM, Spitz FR, Bouvet M, Fuhrman GM, Berger DH. Pancreatic Adenocarcinoma. In: The M. D. Anderson Surgical Oncology Handbook. Lippincott Williams and Wilkins, 367-390, 2006.
Amos KD, Hwang RF. Small-Bowel Malignancies and Carcinoid Tumors. In: The M. D. Anderson Surgical Oncology Handbook. Lippincott Williams and Wilkins, 241-260, 2006.
Hwang RF, Robinson E, Cusack J, Tyler D. Small Bowel Malignancies and Carcinoid Tumors. In: The M.D. Anderson Surgical Oncology Handbook. Lippincott Williams and Wilkins, 193-214, 2002.
Hwang RF, Roseman B. Metastatic Cancer of Unknown Primary Site. In: The M.D. Anderson Surgical Oncology Handbook. Lippincott Williams and Wilkins, 409-424, 2002.
Hwang RF, Baril N, McGarvey M, Chiang M, Formenti S, Skinner K. Principles of Molecular Biology for Cancer Surgeons. In: Surgical Oncology: Multidisciplinary Approach to Difficult Problems. Oxford University Press, 1-43, 2002.
Hwang R. Caring for the Female Cancer Patient – Gynecologic Considerations. In: Surgical Management of Breast Cancer. Cambridge University Press.

Books (edited and written)

Blazer DG, Adjei AA, Akerley W, Bazan JG, Brooks GA, Bruner DW, Campbell GB, Damchek SM, Ganz PA, Hwang R, Keating N, Humar AJ, Nekhlyudov L, Schmitz K, Von Ah D. Diagnosing and Treating Adult Cancers and Associated Impairments, 2021.
Blazer DG, Adjei AA, Akerley W, Bazan JG, Brooks GA, Bruner DW, Campbell GB, Damchek SM, Gane PA, Hwang R, Keating N, Humar AJ, Nekhlyudov L, Schmitz K, Von Ah D. National Academies of Sciences, Engineering and Medicine. National Academies Press, 2021.

Letters to the Editor

Yi M, Meric-Bernstam F, Kuerer HM, Mittendorf EA, Bedrosian E, Lucci A, Hwang RF, Crow JR, Luo S, Hunt KK. Reply to K.J. Van Zee et al. J Clin Oncol 30: 3144-3145, 2012.

Less

CV information above last modified October 15, 2025

Rosa F. Hwang, M.D., F.A.C.S.

About Dr. Hwang

Featured Articles

What is a double mastectomy?

Present Title & Affiliation

Primary Appointment

Dual/Joint/Adjunct Appointment

Education & Training

Degree-Granting Education

Postgraduate Training

Licenses & Certifications

Experience & Service

Faculty Academic Appointments

Administrative Appointments/Responsibilities

Other Professional Positions

Extramural Institutional Committee Activities

Editorial Activities

Honors & Awards

Professional Memberships

Selected Presentations & Talks

Local Presentations

Regional Presentations

National Presentations

International Presentations

Formal Peers

Grant & Contract Support

Selected Publications

Peer-Reviewed Articles

Invited Articles

Review Articles

Professional Educational Materials

Other Articles

Editorials

Abstracts

Book Chapters

Books (edited and written)

Letters to the Editor

Patient Reviews

Request an Appointment

Related Links

Hwang Laboratory

Surgery

Breast Cancer

Pancreatic Cancer

Breast Surgical Oncology Department

Surgical Oncology Department

Surgery Division

Clinical Trials

Help #EndCancer

Give Now

Donate Blood

Shop MD Anderson