Rosalind P. Candelaria, M.D.
Department of Breast Imaging, Division of Diagnostic Imaging
About Dr. Candelaria
Rosalind Candelaria is a Professor at The University of Texas MD Anderson Cancer Center. Her interest centers on how imaging techniques can advance the detection, characterization, and management of breast cancer.
Present Title & Affiliation
Primary Appointment
Professor, Department of Breast Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Use of multimodality breast imaging in the diagnosis and staging of breast cancer
Use of imaging techniques for assessing treatment response in breast cancer
Use of imaging techniques for surveillance of patients with a history of breast cancer
Clinical Interests
Multimodality imaging of the breast and regional nodes
Education & Training
Degree-Granting Education
2004 | The University of Tennessee College of Medicine, Memphis, TN, USA, MD, Medicine |
Postgraduate Training
2009-2010 | Clinical Fellowship, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX |
2005-2009 | Clinical Residency, Diagnostic and Interventional Radiology, The University of Texas Medical School at Houston, Houston, TX |
2004-2005 | Clinical Internship, Preliminary Medicine, The University of Tennessee Health Science Center, Memphis, TN |
Board Certifications
2009 | American Board of Radiology |
Experience & Service
Academic Appointments
Associate Professor, Department of Breast Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2024
Associate Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2019
Associate Professor, Department of Diagnostic and Interventional Radiology, The University of Texas Medical School at Houston, Houston, TX, 2013 - 2023
Selected Publications
Peer-Reviewed Articles
- Musall BC, Adrada BE, Candelaria RP, Mohamed RMM, Abdelhafez AH, Son JB, Sun J, Santiago L, Whitman GJ, Moseley TW, Scoggins ME, Mahmoud HS, White JB, Hwang KP, Elshafeey NA, Boge M, Zhang S, Litton JK, Valero V, Tripathy D, Thompson AM, Yam C, Wei P, Moulder SL, Pagel MD, Yang WT, Ma J, Rauch GM. Quantitative apparent diffusion coefficients from peritumoral regions as early predictors of response to neoadjuvant systemic therapy in triple-negative breast cancer. J Magn Reson Imaging 56(6):1901-1909, 2022. e-Pub 2022. PMID: 35499264.
- Wu C, Jarrett AM, Zhou Z, Elshafeey N, Adrada BE, Candelaria RP, Mohamed RMM, Boge M, Huo L, White JB, Tripathy D, Valero V, Litton JK, Yam C, Son JB, Ma J, Rauch GM, Yankeelov TE. MRI-based digital models forecast patient-specific treatment responses to neoadjuvant chemotherapy in triple-negative breast cancer. Cancer Res 82(18):3394-3404, 2022. e-Pub 2022. PMID: 35914239.
- Huang ML, Hess K, Ma J, Santiago L, Scoggins ME, Arribas E, Adrada BE, Le-Petross HT, Leung JWT, Yang W, Geiser W, Candelaria RP. Prospective comparison of synthesized mammography with DBT and full-field digital mammography with DBT uncovers recall disagreements that may impact cancer detection. Acad Radiol 29(7):1039-1045, 2022. e-Pub 2021. PMID: 34538550.
- Yam C, Abuhadra N, Sun R, Adrada BE, Ding QQ, White JB, Ravenberg EE, Clayborn AR, Valero V, Tripathy D, Damodaran S, Arun BK, Litton JK, Ueno NT, Murthy RK, Lim B, Baez L, Li X, Buzdar AU, Hortobagyi GN, Thompson AM, Mittendorf EA, Rauch GM, Candelaria RP, Huo L, Moulder SL, Chang JT. Molecular characterization and prospective evaluation of pathological response and outcomes with neoadjuvant therapy in metaplastic triple-negative breast cancer. Clin Cancer Res 28(13):2878-2889, 2022. e-Pub 2022. PMID: 35507014.
- Candelaria RP, Adrada BE, Lane DL, Rauch GM, Moulder SL, Thompson AM, Bassett RL, Arribas EM, Le-Petross HT, Leung JWT, Spak DA, Ravenberg EE, White JB, Valero V, Yang WT. Midtreatment ultrasound descriptors as qualitative imaging biomarkers of pathologic complete response in patients with triple negative breast cancer. Ultrasound Med Biol 48(6):1010-1018, 2022. e-Pub 2022. PMID: 35300879.
- Jimenez JE, Abdelhafez A, Mittendorf EA, Elshafeey N, Yung JP, Litton JK, Adrada BE, Candelaria RP, White J, Thompson AM, Huo L, Wei P, Tripathy D, Valero V, Yam C, Hazle JD, Moulder SL, Yang WT, Rauch GM. A model combining pretreatment MRI radiomic features and tumor-infiltrating lymphocytes to predict response to neoadjuvant systemic therapy in triple-negative breast cancer. Eur J Radiol 149:110220, 2022. e-Pub 2022. PMID: 35193025.
- Abuhadra N, Sun R, Litton JK, Rauch GM, Yam C, Chang JT, Seth S, Bassett R, Lim B, Thompson AM, Mittendorf E, Adrada BE, Damodaran S, White J, Ravenberg E, Candelaria R, Arun B, Ueno NT, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim N, Sahin AA, Valero V, Symmans WF, Tripathy D, Moulder S, Huo L. Prognostic impact of high baseline stromal tumor-infiltrating lymphocytes in the absence of pathologic complete response in early-stage triple-negative breast cancer. Cancers (Basel) 14(5), 2022. e-Pub 2022. PMID: 35267631.
- Candelaria RP, Spak DA, Rauch GM, Huo L, Bassett RL, Santiago L, Scoggins ME, Guirguis MS, Patel MM, Whitman GJ, Moulder SL, Thompson AM, Ravenberg EE, White JB, Abuhadra NK, Valero V, Litton J, Adrada BE, Yang WT. BI-RADS ultrasound lexicon descriptors and stromal tumor-infiltrating lymphocytes in triple-negative breast cancer. Acad Radiol 29 Suppl 1:S35-S41, 2022. e-Pub 2021. PMID: 34272161.
- Irajizad E, Wu R, Vykoukal J, Murage E, Spencer R, Dennison JB, Moulder S, Ravenberg E, Lim B, Litton J, Tripathym D, Valero V, Damodaran S, Rauch GM, Adrada B, Candelaria R, White JB, Brewster A, Arun B, Long JP, Do KA, Hanash S, Fahrmann JF. Application of artificial intelligence to plasma metabolomics profiles to predict response to neoadjuvant chemotherapy in triple-negative breast cancer. Front Artif Intell 5:876100, 2022. e-Pub 2022. PMID: 36034598.
- Adrada BE, Candelaria R, Moulder S, Thompson A, Wei P, Whitman GJ, Valero V, Litton JK, Santiago L, Scoggins ME, Moseley TW, White JB, Ravenberg EE, Yang WT, Rauch GM. Early ultrasound evaluation identifies excellent responders to neoadjuvant systemic therapy among patients with triple-negative breast cancer. Cancer 127(16):2880-2887, 2021. e-Pub 2021. PMID: 33878210.
- Musall BC, Abdelhafez AH, Adrada BE, Candelaria RP, Mohamed RMM, Boge M, Le-Petross H, Arribas E, Lane DL, Spak DA, Leung JWT, Hwang KP, Son JB, Elshafeey NA, Mahmoud HS, Wei P, Sun J, Zhang S, White JB, Ravenberg EE, Litton JK, Damodaran S, Thompson AM, Moulder SL, Yang WT, Pagel MD, Rauch GM, Ma J. Functional tumor volume by fast dynamic contrast-enhanced MRI for predicting neoadjuvant systemic therapy response in triple-negative breast cancer. J Magn Reson Imaging 54(1):251-260, 2021. e-Pub 2021. PMID: 33586845.
- Nia ES, Huang ML, Sun SX, Mitchell MP, Myatt JP, Candelaria RP. The mammographic appearance of the BioMonitor implantable loop recorder. Clin Imaging 73:28-30, 2021. e-Pub 2020. PMID: 33296770.
- Guirguis MS, Adrada B, Santiago L, Candelaria R, Arribas E. Mimickers of breast malignancy: Imaging findings, pathologic concordance and clinical management. Insights Imaging 12(53), 2021. e-Pub 2021. PMID: 33877461.
- Nia ES, Adrada BE, Whitman GJ, Candelaria RP, Krishnamurthy S, Bassett RL, M Arribas E. MRI features of pseudoangiomatous stromal hyperplasia with histopathological correlation. Breast J 27(3):242-247, 2021. e-Pub 2021. PMID: 33393706.
- Abdelhafez AH, Musall BC, Adrada BE, Hess K, Son JB, Hwang KP, Candelaria RP, Santiago L, Whitman GJ, Le-Petross HT, Moseley TW, Arribas E, Lane DL, Scoggins ME, Leung JWT, Mahmoud HS, White JB, Ravenberg EE, Litton JK, Valero V, Wei P, Thompson AM, Moulder SL, Pagel MD, Ma J, Yang WT, Rauch GM. Tumor necrosis by pretreatment breast MRI: Association with neoadjuvant systemic therapy (NAST) response in triple-negative breast cancer (TNBC). Breast Cancer Res Treat 185(1):1-12, 2021. e-Pub 2020. PMID: 32920733.
- Bragg A, Candelaria R, Adrada B, Huang M, Rauch G, Santiago L, Scoggins M, Whitman G. Imaging of noncalcified ductal carcinoma in situ. J Clin Imaging Sci 11(34):34, 2021. e-Pub 2021. PMID: 34221643.
- Roy M, Teshome M, Damodaran S, Sahin AA, Khazai L, Arribas E, Candelaria RP, Scoggins ME, Lane DL, Giordano SH, Albarracin CT, Prieto VG, Nagarajan P. Male mammary Paget disease: A tale of 2 contrasting cases. Am J Dermatopathol 42(12):981-985, 2020. PMID: 33289978.
- Scoggins ME, Arun BK, Candelaria RP, Dryden MJ, Wei W, Son JB, Ma J, Dogan BE. Should abbreviated breast MRI be compliant with American College of Radiology requirements for MRI accreditation?. Magn Reson Imaging 72:87-94, 2020. e-Pub 2020. PMID: 32622851.
- Yalniz C, Meis JM, Wang WL, Huo L, Candelaria RP, Adrada BE, Lane D, Santiago L, Huang ML. Proliferative fasciitis mimicking sarcoma in the breast. Breast J 26(10):2072-2074, 2020. e-Pub 2020. PMID: 32854140.
- Candelaria RP, Adrada BE, Hess K, Santiago L, Lane DL, Thompson AM, Moulder SL, Huang ML, Arribas EM, Rauch GM, Leung JWT, Symmans WF, Valero V, Ravenberg EE, White JB, Yang WT. Axillary ultrasound during neoadjuvant systemic therapy in triple-negative breast cancer patients. Eur J Radiol 130:109170, 2020. e-Pub 2020. PMID: 32777736.
- Park KU, Weiss A, Rosso K, Yi M, Hunt K, Kuerer H, Hanson SE, Candelaria R, Tevis S, Thompson A. Use of mammographic measurements to predict complications after nipple-sparing mastectomy in BRCA mutation carriers. Ann Surg Oncol 27(2):367-372, 2020. e-Pub 2019. PMID: 31399819.
- Candelaria RP, Adrada BE, Wei W, Thompson AM, Santiago L, Lane DL, Huang ML, Arribas EM, Rauch GM, Symmans WF, Gilcrease MZ, Huo L, Lim B, Ueno NT, Moulder SL, Yang WT. Imaging features of triple-negative breast cancers according to androgen receptor status. Eur J Radiol 114:167-174, 2019. e-Pub 2019. PMID: 31005169.
- Speer ME, Huang ML, Dogan BE, Adrada BE, Candelaria RP, Hess KR, Hansakul P, Yang WT, Rauch GM. High risk breast lesions identified on MRI-guided vacuum assisted needle biopsy: Outcome of surgical excision and imaging follow-up. Br J Radiol 91(1090):20180300, 2018. e-Pub 2018. PMID: 29947265.
- Rauch GM, Kuerer HM, Adrada B, Santiago L, Moseley T, Candelaria RP, Arribas E, Sun J, Leung JWT, Krishnamurthy S, Yang WT. Biopsy feasibility trial for breast cancer pathologic complete response detection after neoadjuvant chemotherapy: Imaging assessment and correlation endpoints. Ann Surg Oncol 25(7):1953-1960, 2018. e-Pub 2018. PMID: 29667115.
- Kuerer HM, Rauch GM, Krishnamurthy S, Adrada BE, Caudle AS, DeSnyder SM, Black DM, Santiago L, Hobbs BP, Lucci A, Gilcrease M, Hwang RF, Candelaria RP, Chavez-MacGregor M, Smith BD, Arribas E, Moseley T, Teshome M, Miggins MV, Valero V, Hunt KK, Yang WT. A clinical feasibility trial for identification of exceptional responders in whom breast cancer surgery can be eliminated following neoadjuvant systemic therapy. Ann Surg 267(5):946-951, 2018. e-Pub 2017. PMID: 28549010.
- Santiago L, Candelaria RP, Huang ML. MR imaging-guided breast interventions: Indications, key principles, and imaging-pathology correlation. Magn Reson Imaging Clin N Am 26(2):235-246, 2018. e-Pub 2018. PMID: 29622128.
- Candelaria RP, Hansakul P, Thompson AM, Le-Petross H, Valero V, Bassett R, Huang ML, Santiago L, Adrada BE. Analysis of stereotactic biopsies performed on suspicious calcifications identified within 24 months after completion of breast conserving surgery and radiation therapy for early breast cancer: Can biopsy be obviated?. Am J Surg 215(4):693-698, 2018. e-Pub 2017. PMID: 28712671.
- Candelaria RP, Krishnamurthy S, Huang ML, Santiago L, Adrada BE. Imaging and pathological findings in a case of invasive squamous cell carcinoma of the breast. Breast J 24(2):203-204, 2018. e-Pub 2017. PMID: 28727282.
- Dogan BE, Scoggins ME, Son JB, Wei W, Candelaria R, Yang WT, Ma J. American College of Radiology-Compliant short protocol breast MRI for high-risk breast cancer screening: A prospective feasibility study. AJR Am J Roentgenol 210(1):1-8, 2018. e-Pub 2017. PMID: 29091003.
- Santiago L, Adrada BE, Huang ML, Wei W, Candelaria RP. Breast cancer neoplastic seeding in the setting of image-guided needle biopsies of the breast. Breast Cancer Res Treat 166(1):29-39, 2017. e-Pub 2017. PMID: 28730339.
- Huang ML, Hess K, Candelaria RP, Eghtedari M, Adrada BE, Sneige N, Fornage BD. Comparison of the accuracy of US-guided biopsy of breast masses performed with 14-gauge, 16-gauge and 18-gauge automated cutting needle biopsy devices, and review of the literature. Eur Radiol 27(7):2928-2933, 2017. e-Pub 2016. PMID: 27844099.
- Huang ML, Speer M, Dogan BE, Rauch GM, Candelaria RP, Adrada BE, Hess KR, Yang WT. Imaging-concordant benign MRI-guided vacuum-assisted breast biopsy may not warrant MRI follow-up. AJR Am J Roentgenol 208(4):1-7, 2017. e-Pub 2017. PMID: 28140609.
- Candelaria RP, Bassett RL, Symmans WF, Ramineni M, Moulder SL, Kuerer HM, Thompson AM, Yang WT. Performance of mid-treatment breast ultrasound and axillary ultrasound in predicting response to neoadjuvant chemotherapy by breast cancer subtype. Oncologist 22(4):394-401, 2017. e-Pub 2017. PMID: 28314842.
- Candelaria RP, Huang ML, Adrada BE, Bassett R, Hunt KK, Kuerer HM, Smith BD, Chavez-MacGregor M, Yang WT. Incremental cancer detection of locoregional restaging with diagnostic mammography combined with whole breast and regional nodal ultrasound in women with newly-diagnosed breast cancer. Acad Radiol 24(2):191-199, 2017. e-Pub 2016. PMID: 27955877.
- Shin K, Caudle AS, Kuerer HM, Santiago L, Candelaria RP, Dogan B, Leung J, Krishnamurthy S, Yang W. Radiologic mapping for targeted axillary dissection: Needle biopsy to excision. AJR Am J Roentgenol 207(6):1-8, 2016. e-Pub 2016. PMID: 27726422.
- He H, Plaxco JS, Wei W, Huo L, Candelaria RP, Kuerer HM, Yang WT. Incremental cancer detection using breast ultrasonography versus breast magnetic resonance imaging in the evaluation of newly diagnosed breast cancer patients. Br J Radiol 89(1065):20160401, 2016. e-Pub 2016. PMID: 27384241.
- Caudle AS, Yang WT, Krishnamurthy S, Mittendorf EA, Black DM, Gilcrease MZ, Bedrosian I, Hobbs BP, DeSnyder SM, Hwang RF, Adrada BE, Shaitelman SF, Chavez-MacGregor M, Smith BD, Candelaria RP, Babiera GV, Dogan BE, Santiago L, Hunt KK, Kuerer HM. Improved axillary evaluation following neoadjuvant therapy for patients with node-positive breast cancer using selective evaluation of clipped nodes: Implementation of targeted axillary dissection. J Clin Oncol 34(10):1072-8, 2016. e-Pub 2016. PMID: 26811528.
- Shaitelman SF, Tereffe W, Dogan BE, Hess KR, Caudle AS, Valero V, Stauder MC, Krishnamurthy S, Candelaria RP, Strom EA, Woodward WA, Hunt KK, Buchholz TA, Whitman GJ. Role of ultrasonography of regional nodal basins in staging triple-negative breast cancer and implications for local-regional treatment. Int J Radiat Oncol Biol Phys 93(1):102-10, 2015. e-Pub 2015. PMID: 26279028.
- Candelaria R, Fornage BD. Second-look US examination of MR-detected breast lesions. J Clin Ultrasound 39(3):115-21, 2011. e-Pub 2010. PMID: 21387324.
- Keembiyehetty CN, Candelaria RP, Majumdar G, Raghow R, Martinez-Hernandez A, Solomon SS. Paradoxical regulation of Sp1 transcription factor by glucagon. Endocrinology 143(4):1512-20, 2002. PMID: 11897710.
Invited Articles
- Huang ML, Adrada BE, Candelaria R, Thames D, Dawson D, Yang WT. Stereotactic breast biopsy: Pitfalls and pearls. Tech Vasc Interv Radiol 17(1):32-39, 2014. PMID: 24636329.
- Candelaria RP, Hwang L, Bouchard RR, Whitman GJ. Breast ultrasound: Current concepts. Semin Ultrasound CT MR 34(3):213-25, 2013. PMID: 23768888.
Abstracts
- Caudle AS, Yang WT, Mittendorf EA, Black DM, Gilcrease M, Bedrosian I, Hobbs BP, Candelaria RP, Babiera G, Dogan B, Santiago L, Hunt K, Krishnamurthy S, Kuerer HM. Assessment for residual nodal disease after neoadjuvant chemotherapy with image-guided surgery. J Clin Oncol 32(26 suppl), 2014.
Book Chapters
- Candelaria R. Fat-containing mass. In: Diagnostic Imaging: Breast. 2nd Edition. Amirsys, Inc: Canada, 4.14-4.19, 2013.
- Candelaria R. High-density mass. In: Diagnostic Imaging: Breast. 2nd Edition. Amirsys, Inc: Canada, 4.42-4.45, 2013.
- Candelaria R, Yang WT. Posterior enhancement (US). In: Diagnostic Imaging: Breast. 2nd Edition. Amirsys, Inc: Canada, 4.196-4.201, 2013.
- Candelaria R, Yang WT. Posterior shadowing (US). In: Diagnostic Imaging: Breast. 2nd Edition. Amirsys, Inc: Canada, 4.202-4.207, 2013.
Patient Reviews
CV information above last modified December 02, 2024