Jennifer R Wang, MD, PhD, ScM, FRCSC
Department of Head and Neck Surgery, Division of Surgery
About Dr. Jennifer R Wang
Dr. Wang is an Associate Professor in the Department of Head and Neck Surgery at MD Anderson Cancer Center. Her clinical practice is centered on providing the highest quality of care for patients with head and neck cancers. She practices within both the Head and Neck center and the Endocrine center. Dr. Wang is also a genetic epidemiologist, having completed a Clinician-Investigator Program with a Master of Science in Genetic Epidemiology from the Johns Hopkins Bloomberg School of Public Health. She leads a translational laboratory focused on head and neck cancer/thyroid cancer genomics.
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Assistant Professor, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas
Research Interests
Dr. Wang’s research focuses on incorporating genomic biomarkers with clinicopathologic features to predict outcomes in head and neck cancers. Dr. Wang has a special interest in examining genomic alterations in aggressive thyroid cancers in the context of tumor evolution, treatment resistance, and survival outcomes.
Clinical Interests
Education & Training
Degree-Granting Education
| 2023 | Johns Hopkins University, Baltimore, Maryland, US, Genetic Epidemiology, Ph.D |
| 2015 | Johns Hopkins University, Baltimore, Maryland, US, Master of Science, Genetic Epidemiology, ScM |
| 2010 | University of Toronto, Toronto, CA, MD |
| 2006 | McMaster University, Hamilton, CA, Bachelor of Health Sciences, BHSc |
Postgraduate Training
| 2018-2018 | Healthcare Leadership and Management, Johns Hopkins Carey Business School, Baltimore, Maryland |
| 2017-2018 | Clinical Fellowship, Advanced Head and Neck Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2013-2015 | Research Residency, Clinician Investigator Program, University of Toronto, Toronto |
| 2010-2017 | Clinical Residency, Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto |
Licenses & Certifications
| 2018 | Texas Medical Board |
| 2017 | Royal College of Physicians and Surgeons of Canada |
| 2010 | Medical Council of Canada |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2024
Administrative Appointments/Responsibilities
Associate Medical Director, Endocrine Center, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - Present
Institutional Committee Activities
Associate Member, Genetics and Epigenetics (G&E) Program, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, 2023 - Present
Member, Academic Review Committee, 2023 - Present
Member, Basic and Translational Research Committee, Division of Surgery, MD Anderson Cancer Center, 2023 - Present
Member, Faculty Senate, MD Anderson Cancer Center, 2022 - Present
Member, Physician Advisory Council, MD Anderson Cancer Center, 2019 - 2021
Voting Member, Data and Biospecimen Access Committee (DBAC), MD Anderson Cancer Center, 2019 - 2021
Member, Endocrine Center Steering Committee, MD Anderson Cancer Center, 2019 - Present
Member, Department of Head and Neck Surgery Clinical Operations Team (HNS COLT), MD Anderson Cancer Center, 2019 - Present
Member, Advisory Committee for the Appointment of the Chair of Otolaryngology-Head and Neck Surgery, University of Toronto, 2017
Member, Residency Selection Committee, University of Toronto, Department of Head and Neck, 2016 - 2018
Member, Undergraduate MD Program Admissions Committee, University of Toronto, Faculty of Medicine, 2015
Member, Clerkship Curriculum Review Committee (Ambulatory Community Experience), University of Toronto, 2008 - 2010
Honors & Awards
| 2025 | International Thyroid Congress Travel Grant, Latin American Thyroid Society |
| 2023 | First Place Poster Award, American Head & Neck Society (AHNS) 11th International Conference on Head and Neck Cancer |
| 2018 | Fellow, ECCO-AACR-EORTC-ESMO Methods in Clinical Cancer Research |
| 2018 | PhD Tuition Scholarship, Johns Hopkins Bloomberg School of Public Health |
| 2018 | ASCO Merit Award, Conquer Cancer the ASCO Foundation |
| 2018 | Conquer Cancer Foundation Merit Award, American Society of Clinical Oncology |
| 2017 | Sigma Xi The Scientific Research Honor Society |
| 2014 | Alando J. Ballantyne Resident Research Award, American Head and Neck Society |
| 2014 | Clinician Investigation Program Salary Award, Ontario Ministry of Health and Long-Term Care |
| 2014 | Joseph M. West Family Memorial Fund Scholarship, University of Toronto |
| 2014 | Master’s Tuition Scholarship, Johns Hopkins Bloomberg School of Public Health |
| 2014 | Raymond H.W. Ng Graduate Studies Award, University of Toronto |
| 2014 | William S. Fenwick Research Fellowship Award, University of Toronto |
| 2014 - 2015 | Chapnik, Freeman & Friedberg Clinician-Scientist Award, University of Toronto |
| 2013 | Poster Award: Head and Neck Surgery, Triological Society Annual Meeting at COSM |
| 2012 | Best Paper: Work Undertaken by PGY2 Residents During Clinical Rotations, Otolaryngology-Head and Neck Surgery, University of Toronto |
| 2010 | Hugh Barber Scholarship in Otolaryngology, University of Toronto |
| 2006 | Summa Cum Laude, McMaster University |
| 2005 | Senate Scholarship, McMaster University |
| 2004 - 2005 | Bachelor of Health Sciences Research Scholarship, McMaster University |
| 2002 - 2006 | Queen Elizabeth II Aiming for the Top Scholarship, Province of Ontario |
| 2002 | Golden Key International Honour Society |
| 2002 | McMaster Honour Award University Entrance Scholarship, McMaster University |
| 2002 | Rotary Youth Citizen Award, City of Guelph |
| 2002 | W.C. Wood University Entrance Scholarship, W.C. Wood University |
| 2002 - 2006 | Dean’s Honour List |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2019. De-Differentiated and Anaplastic Thyroid Cancer. Conference. MD Anderson Cancer Center Current Concepts in Head and Neck Cancer. Houston, TX, US.
National Presentations
- 2025. Determinants of Response to DTP in BRAFV600E Mutated ATC. Invited. ITOG 2025 Annual Meeting Program. Ann Arbor, Michigan, US.
- 2024. Updates in the Management of Medullary Thyroid Cancer. Invited. 2024 Current Concepts in Head and Neck Oncology. New York, NY, US.
- 2024. Panel Discussion on Thyroid Cancers. Invited. 2024 Current Concepts in Head and Neck Oncology. New York, NY, US.
- 2023. Anaplastic Thyroid Cancer: Translational Insights. Invited. Boston Head & Neck Cancer Symposium. Boston, MA, US.
- 2022. Interdisciplinary Management of an Oral Lesion (Case Presentations and Q & A Session). Invited. Oral Cancer Diagnosis and Treatment. Houston, TX, US.
- 2022. Head and Neck Clinical Exam. Invited. Oral Cancer Diagnosis and Treatment. Houston, TX, US.
- 2020. Fellowship Grand Rounds: Advances in Anaplastic Thyroid Carcinoma. Invited. University of Toronto. Virtual, US.
- 2019. Poster: Prior cancers among patients newly diagnosed with anaplastic thyroid carcinoma: prevalence and impact on survival. Conference. American Thyroid Association Conference 2019. Chicago, IL, US.
International Presentations
- 2025. Anaplastic Thyroid Cancer. Invited. 17th International Thyroid Congress. Rio de Janeiro, BR.
- 2025. Anaplastic Thyroid carcinoma: evolving biological understanding and treatment paradigms. Invited. Science Web 1Hr Seminar Series. Brussels, BE.
- 2024. Surgery for Advanced Thyroid Cancers. Invited. 27th Annual International ThyCa Conference. Houston, US.
- 2024. Symposium: Personalizing Thyroid Cancer Therapy - Dissecting the single cell landscape of thyroid cancer. Invited. ENDO 2024. Boston, US.
- 2024. Dissecting the Evolutionary Trajectory of Anaplastic Thyroid Carcinoma. Invited. 2024 IADR/AADOCR/CADR General Session. New Orleans, US.
- 2023. Driving Drug Discovery for Rare Cancers. Invited. The Mark Foundation Scientific Symposium 2023. New York, US.
- 2023. Panel Discussion: Question and Answer Session, Mike Tuttle, Moderator. Invited. 26th International ThyCa Conference. Denver, US.
Formal Peers
- 2021. International Thyroid Tumor Board. Invited, US.
- 2019. Neo-Adjuvant treatment of anaplastic thyroid cancer. Visiting. Salt Lake City, UT, US.
Grant & Contract Support
| Date: | 2022 - 2027 |
| Title: | Statistical methods for genomic analysis of heterogeneous tumors |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1 R01 CA268380-01A1 |
| Date: | 2021 - 2024 |
| Title: | Targeted Therapy Combined with Pembrolizumab in Anaplastic Thyroid Cancer: Two Phase II Clinical Trials |
| Funding Source: | Gateway For Cancer Research |
| Role: | Co-PI |
| Date: | 2020 - 2022 |
| Title: | Intratumor Heterogeneity in Anaplastic Thyroid Carcinoma: Implications for Treatment Resistance |
| Funding Source: | The Mark Foundation for Cancer Research, ASPIRE Grant |
| Role: | PI |
| Date: | 2019 - 2022 |
| Title: | Defining the Role of SWI/SNF Mutations in Anaplastic Thyroid Carcinoma |
| Funding Source: | American Thyroid Association and ThyCA: Thyroid Cancer Survivors’ Association (ThyCa) |
| Role: | PI |
| Date: | 2014 - 2015 |
| Title: | Chromatin Remodeling and Head and Neck Squamous Cell Carcinoma |
| Funding Source: | American Head and Neck Society Alando J. Ballantyne Resident Research Pilot Grant |
| Role: | PI |
| Title: | Expression of chromatin proteins in primary oral squamous cell carcinoma tumors |
| Funding Source: | Harry Barberian Research Grant |
| Role: | PI |
| Title: | Clonal hematopoiesis as a targetable mechanism of resistance to therapy in thyroid cancer |
| Funding Source: | NIH |
| Role: | Co-I |
| ID: | FP00024371 |
Selected Publications
Peer-Reviewed Articles
- Cabanillas, ME, Busaidy, NL, Gunn, GB, Iyer, PC, Ferrarotto, R, Gule-Monroe, MK, Maniakas, A, Williams, MD, Liu, S, Fellman, B, Spiotto, MT, Hamidi, S, Akhave, NS, Lee, A, Wang, RJ, De Sousa, LG, Marczyk, VR, Zafereo, M, Dadu, R. Adjuvant Pembrolizumab after Upfront Multimodal Therapy for Stage IVB Anaplastic Thyroid Cancer. Thyroid 35(7):763-770, 2025. e-Pub 2025. PMID: 40609521.
- Dagher SA, Learned KO, Dagher R, Wang JR, Zhao X, Hosseini SM, Maniakas A, Cabanillas ME, Busaidy NL, Dadu R, Iyer P, Zafereo ME, Khalaf AM. [18F]-Fluorodeoxyglucose Uptake as a Marker of Residual Anaplastic and Poorly Differentiated Thyroid Carcinoma Following BRAF-Targeted Therapy. AJNR Am J Neuroradiol 46(6):1260-1267, 2025. e-Pub 2025. PMID: 39572200.
- Wang JR, Mark Zafereo, Naifa Lamki Busaidy, Ramona Dadu, Priyanka C Lyer, Steven G Waguespack, Li Xu, Anastasios Maniakas, Victoria Banuchi, Stephen Yenzen Lai, Stephen B Chinn, Jessica Lyn Geiger, Kathleen Claire Kerrigan, Saad A Khan, Eric J Moore, Mabel M Ryder, Joseph Scharpf, Francis P Worden, Michelle D Williams, Maria E Cabanillas. Neoadjuvant pembrolizumab in combination with dabrafenib and trametinib (DTP) for BRAF V600E-mutated anaplastic thyroid cancer (BRAFm-ATC): A multicenter phase 2 trial. JCO 43(16_suppl):6008-6008, 2025. e-Pub 2025.
- Hamidi, S, Dadu, R, Iyer, PC, Busaidy, NL, Maniakas, A, Wang, RJ, Banuchi, VE, Hosseini, SM, Williams, MD, Zafereo, M, Cabanillas, ME. Circulating Tumor DNA as a Biomarker for Disease Surveillance in Anaplastic Thyroid Cancer. JCO Precision Oncology 9, 2025. e-Pub 2025. PMID: 40570261.
- Cabanillas, ME, Akhave, NS, Banuchi, VE, Busaidy, NL, Dadu, R, Ferrarotto, R, Gunn, GB, Hamidi, S, Hofmann, M, Hosseini, SM, Iyer, PC, Lai, SY, Lee, A, Maniakas, A, Ning, M, Spiotto, MT, Wang, RJ, Williams, MD, Zafereo, M. Reimagining the Therapeutic Approach for Anaplastic Thyroid Cancer. Thyroid 35(5):462-470, 2025. e-Pub 2025. PMID: 40388579.
- Li, S, Zheng, G, Xu, L, Goswami, M, Zafereo, M, Sherman, SI, Li, G, Sturgis, EM, Wang, RJ. Polygenic Score for Clinicopathologic Features and Survival Outcomes in Papillary Thyroid Carcinoma. JAMA Otolaryngology - Head and Neck Surgery 151(2):113-120, 2025. e-Pub 2025. PMID: 39602114.
- Castellanos LE, Zafereo ME, Sturgis EM, Wang JR, Ying AK, Waguespack SG. Pediatric Papillary Thyroid Carcinoma: Outcomes After Surgery Without Adjuvant Radioactive Iodine. J Clin Endocrinol Metab 110(2):e208-e217, 2025. e-Pub 2025. PMID: 39163248.
- Marczyk, VR, Fazeli, S, Dadu, R, Busaidy, NL, Iyer, PC, Hu, MI, Sherman, SI, Hamidi, S, Hosseini, SM, Williams, MD, Ahmed, S, Routbort, MJ, Luthra, R, Roy Chowdhuri, S, San Lucas, FA, Patel, KP, Hong, DS, Zafereo, M, Wang, RJ, Maniakas, A, Waguespack, SG, Cabanillas, ME. NTRK Fusion-Positive Thyroid Carcinoma. JCO Precision Oncology 9, 2025. e-Pub 2025. PMID: 39983078.
- Wang JR, Zafereo ME, Cabanillas ME, Wu CC, Xu L, Dai Y, Wang W, Lai SY, Henderson Y, Erasmus L, Williams MD, Joshu C, Ray D. The Association Between Thyroid Differentiation Score and Survival Outcomes in Papillary Thyroid Carcinoma. J Clin Endocrinol Metab 110(2):356-363, 2025. e-Pub 2025. PMID: 39087944.
- Bronk, JK, Augustyn, A, Mohamed, AS, Fuller, C, Garden, AS, Moreno, AC, Lee, A, Morrison, WH, Phan, J, Reddy, JP, Rosenthal, DI, Spiotto, MT, Frank, SJ, Dadu, R, Busaidy, NL, Zafereo, M, Wang, RJ, Maniakas, A, Ferrarotto, R, Iyer, PC, Cabanillas, ME, Gunn, GB. Patterns of loco-regional progression and patient outcomes after definitive-dose radiation therapy for anaplastic thyroid cancer. Radiotherapy and Oncology 202, 2025. e-Pub 2025. PMID: 39489425.
- Cabanillas ME, Dadu R, Ferrarotto R, Gule-Monroe M, Liu S, Fellman B, Williams MD, Zafereo M, Wang JR, Lu C, Ning M, McKinley BA, Woodman SE, Duose D, Gunn GB, Busaidy NL. Anti-Programmed Death Ligand 1 Plus Targeted Therapy in Anaplastic Thyroid Carcinoma: A Nonrandomized Clinical Trial. JAMA Oncol 10(12):1672-1680, 2024. e-Pub 2024. PMID: 39446377.
- John, E, Lesluyes, T, Baker, T, Tarabichi, M, Gillenwater, AM, Wang, RJ, Van Loo, P, Zhao, X. Reconstructing oral cavity tumor evolution through brush biopsy. Scientific reports 14(1), 2024. e-Pub 2024. PMID: 39343812.
- Li SZ, Zheng G, Xu L, Goswami M, Zafereo M, Sherman SI, Li G, Sturgis EM, Wang JR. Polygenic Score for Clinicopathologic Features and Survival Outcomes in Papillary Thyroid Carcinoma. JAMA Otolaryngol Head Neck Surg, 2024.
- Wang JR, Marczyk VR, Fazeli S, Dadu R, Busaidy NL, Iyer P, Hu MI, Sherman SI, Hamidi S, Hosseini SM, Williams MD, Ahmed S, Routbort MJ, Luthra R, Chowdhuri S, San Lucas FA, Patel KP, Hong DS, Zafereo M, Wang JR, Patel KP, Maniakas A, Waguespack SG. NTRK Fusion-Positive Thyroid Carcinoma: From Diagnosis to Targeted Therapy. JCO Precis Oncol. e-Pub 2024.
- Hamidi S, Iyer PC, Dadu R, Gule-Monroe MK, Maniakas A, Zafereo ME, Wang JR, Busaidy NL, Cabanillas ME. Checkpoint Inhibition in Addition to Dabrafenib/Trametinib for BRAFV600E Mutated Anaplastic Thyroid Carcinoma. Thyroid 34(3):336-346, 2024. e-Pub 2024. PMID: 38226606.
- Maniakas A, Sullivan A, Hu MI, Busaidy NL, Cabanillas ME, Dadu R, Waguespack SG, Fisher SB, Graham PH, Gross ND, Grubbs EG, Perrier ND, Wang JR, Gunn B, Garden AS, Megahed R, Navuluri S, Li X, Williams MD, Zafereo M. Decreasing utilization for postoperative radiation therapy in locoregionally advanced medullary thyroid cancer. Head Neck 46(2):328-335, 2024. e-Pub 2024. PMID: 38009416.
- Wang JR, Zafereo ME, Wang W, Joshu C, Ray D. Association of polygenic score with tumor molecular subtypes in papillary thyroid carcinoma. J Clin Endocrinol Metab 109(1):e306-e313, 2023. e-Pub 2023. PMID: 37453101.
- Lu L, Wang JR, Henderson YC, Bai S, Yang J, Hu M, Shiau CK, Pan T, Yan Y, Tran TM, Li J, Kieser R, Zhao X, Wang J, Nurieva R, Williams MD, Cabanillas ME, Dadu R, Busaidy NL, Zafereo M, Navin N, Lai SY, Gao R. Anaplastic transformation in thyroid cancer revealed by single cell transcriptomics. J Clin Invest 133(11), 2023. e-Pub 2023. PMID: 37053016.
- Zhao X, Wang JR, Dadu R, Busaidy NL, Xu L, Learned KO, Chasen NN, Vu T, Maniakas A, Eguia AA, Diersing J, Gross ND, Goepfert R, Lai SY, Hofmann MC, Ferrarotto R, Lu C, Gunn GB, Spiotto MT, Subbiah V, Williams MD, Cabanillas ME, Zafereo ME. Surgery after BRAF-directed therapy is associated with improved survival in BRAFV600E mutant anaplastic thyroid cancer: a single center retrospective cohort study. Thyroid 33(4):484-491, 2023. e-Pub 2023. PMID: 36762947.
- Chen YH, Cabanillas M, Sperling J, Xu L, Goswami M, Maniakas A, Williams MD, Lai SY, Busaidy N, Dadu R, Zafereo ME, Wang JR. Prior thyroid and non-thyroid cancer history do not significantly alter overall survival in patients diagnosed with anaplastic thyroid carcinoma. Thyroid 33(3):321-329, 2023. e-Pub 2023. PMID: 36511380.
- Shenson JA, Zafereo ME, Lee M, Contrera KJ, Feng L, Boonsripitayanon M, Gross N, Goepfert R, Maniakas A, Wang JR, Grubbs L, Vaporciyan A, Hofstetter W, Swisher S, Mehran R, Rice D, Sepesi B, Antonoff M, Cabanillas M, Busaidy N, Dadu R, Silver NL. Clinical outcomes of combined cervical and transthoracic surgical approaches in patients with advanced thyroid cancer. Head Neck 45(3):547-554, 2023. e-Pub 2023. PMID: 36524701.
- Contrera KJ, Gule-Monroe MK, Hu MI, Cabanillas ME, Busaidy NL, Dadu R, Waguespack SG, Wang JR, Maniakas A, Lai SY, Diersing J, Kwon M, Grubbs EG, Subbiah V, Williams MD, Zafereo ME. Neoadjuvant Selective RET Inhibitor for Medullary Thyroid Cancer: A Case Series. Thyroid 33(1):129-132, 2023. e-Pub 2023. PMID: 36503246.
- Cao S, Wang JR, Ji S, Yang P, Dai Y, Guo S, Montierth MD, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Viale A, Zhang J, Nykter M, Czerniak BA, Brown PH, Swanton C, Msaouel P, Maitra A, Kopetz S, Campbell P, Speed TP, Boutros PC, Zhu H, Urbanucci A, Demeulemeester J, Van Loo P, Wang W. Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. Nat Biotechnol 40(11):1624-1633, 2022. e-Pub 2022. PMID: 35697807.
- Wang JR, Montierth M, Xu L, Goswami M, Zhao X, Cote G, Wang W, Iyer P, Dadu R, Busaidy NL, Lai SY, Gross ND, Ferrarotto R, Lu C, Gunn GB, Williams MD, Routbort M, Zafereo ME, Cabanillas ME. Impact of Somatic Mutations on Survival Outcomes in Patients With Anaplastic Thyroid Carcinoma. JCO Precis Oncol 6:e2100504, 2022. e-Pub 2022. PMID: 35977347.
- Maniakas A, Henderson YC, Hei H, Peng S, Chen Y, Jiang Y, Ji S, Cardenas M, Chiu Y, Bell D, Williams MD, Hofmann MC, Scherer SE, Wheeler DA, Busaidy NL, Dadu R, Wang JR, Cabanillas ME, Zafereo M, Johnson FM, Lai SY. Novel anaplastic thyroid cancer PDXs and cell lines: Expanding preclinical models of genetic diversity. J Clin Endocrinol Metab 106(11):e4652-e4665, 2021. e-Pub 2021. PMID: 34147031.
- Qin Y, Wang JR, Wang Y, Iyer P, Cote GJ, Busaidy NL, Dadu R, Zafereo M, Williams MD, Ferrarotto R, Gunn GB, Wei P, Patel K, Hofmann MC, Cabanillas ME. Clinical Utility of Circulating Cell-free DNA Mutations in Anaplastic Thyroid Carcinoma. Thyroid 31(8):1235-1243, 2021. e-Pub 2021. PMID: 33599171.
- Henderson YC, Mohamed ASR, Maniakas A, Chen Y, Powell RT, Peng S, Cardenas M, Williams MD, Bell D, Zafereo ME, Wang JR, Scherer SE, Wheeler DA, Cabanillas ME, Hofmann MC, Johnson FM, Stephan CC, Sandulache V, Lai SY. A High-Throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma. J Clin Endocrinol Metab 39(5):599-608. e-Pub 2021. PMID: 34120183.
- Gao R, Bai S, Henderson YC, Lin Y, Schalck A, Yan Y, Kumar T, Hu M, Sei E, Davis A, Wang F, Shaitelman SF, Wang JR, Chen K, Moulder S, Lai SY, Navin NE. Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes. Nat Biotechnol 39(5):599-608, 2021. e-Pub 2021. PMID: 33462507.
- Jozaghi Y, Zafereo M, Williams MD, Gule-Monroe MK, Wang JR, Grubbs EG, Vaporciyan A, Hu MI, Busaidy N, Dadu R, Waguespack SG, Subbiah V, Cabanillas M. Neoadjuvant selpercatinib for advanced medullary thyroid cancer. Head Neck 43(1):E7-E12, 2021. e-Pub 2021. PMID: 33169506.
- Jiang Y, Yu K, Ji S, Shin SJ, Cao S, Montierth MD, Huang L, Kopetz S, Msaouel P, Wang JR, Kimmel M, Zhu H, Wang W. CliP: subclonal architecture reconstruction of cancer cells in DNA sequencing data using a penalized likelihood model. bioRxiv, 2021. e-Pub 2021.
- Wang JR, Cao S, Ji S, Yang P, Chen J, Montierth MD, Shen JP, Lee, JJ, Guerrero PA, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Vaile A, Zhang J, Maitra A, Kopetz S, Campbell P, Speed TP, Boutros PC, Urbanucci A, Zhu H, Demeulemeester J, Van Loo P, Wang W. Differing total mRNA expression shapes the molecular and clinical phenotype of cancer. bioRxiv, 2020. e-Pub 2020.
- Cabanillas ME, Dadu R, Iyer P, Wanland KB, Busaidy NL, Ying A, Gule-Monroe M, Wang JR, Zafereo M, Hofmann MC. Acquired Secondary RAS Mutation in BRAFV600E-Mutated Thyroid Cancer Patients Treated with BRAF Inhibitors. Thyroid 30(9):1288-1296, 2020. e-Pub 2020. PMID: 32216548.
- Maniakas A, Dadu R, Busaidy NL, Wang JR, Ferrarotto R, Lu C, Williams MD, Gunn GB, Hofmann MC, Cote G, Sperling J, Gross ND, Sturgis EM, Goepfert RP, Lai SY, Cabanillas ME, Zafereo M. Evaluation of Overall Survival in Patients With Anaplastic Thyroid Carcinoma, 2000-2019. JAMA Oncol 6(9):1397-1404, 2020. e-Pub 2020. PMID: 32761153.
- Anastasios Maniakas A, Mohamed A, Henderson Y, Hei H, Peng S, Bell D, Williams MD, Scherer S, Wheeler DA, Clayman GL, Zafereo M, Wang JR, Cabanillas ME, Stephan C, Johnson FM, Lai SY. In vivo drug response evaluation in anaplastic thyroid cancer patient-derived tumor xenografts following high-throughput screening. American Association for Cancer Research 80(16 Supplement):1662-1662, 2020. e-Pub 2020.
- Jozaghi Y, Zafereo ME, Perrier ND, Wang JR, Grubbs E, Gross ND, Fisher S, Sturgis EM, Goepfert RP, Lai SY, Best C, Busaidy NL, Cabanillas ME, Dadu R, Gagel RF, Habra MA, Hu MI, Jimenez C, Sherman SI, Thosani S, Varghese J, Waguespack SG, Weitzman S, Ying AK, Graham PH. Endocrine surgery in the Coronavirus disease 2019 pandemic: Surgical Triage Guidelines. Head Neck 42(6):1325-1328, 2020. e-Pub 2020. PMID: 32437031.
- Ren J, Xu W, Su J, Ren X, Cheng D, Chen Z, Bender N, Mirshams M, Habbous S, de Almeida JR, Perez-Ordonez B, Goldstein DP, Wang JR, Bratman SV, Huang SH, Jang R, Zhao Y, Waterboer T, Hung RJ, Liu G. Multiple imputation and clinico-serological models to predict human papillomavirus status in oropharyngeal carcinoma: An alternative when tissue is unavailable. Int J Cancer 146(8):2166-2174, 2020. e-Pub 2020. PMID: 31269236.
- Wang JR, Nurgalieva Z, Fu S, Tam S, Zhao H, Giordano SH, Hutcheson KA, Lewis CM. Utilization of rehabilitation services in patients with head and neck cancer in the United States: A SEER-Medicare analysis. Head Neck 41(9):3299-3308, 2019. e-Pub 2019. PMID: 31240808.
- Wang JR, Zafereo ME, Dadu R, Ferrarotto R, Busaidy NL, Lu C, Ahmed S, Gule-Monroe MK, Williams MD, Sturgis EM, Goepfert RP, Gross ND, Lai SY, Gunn GB, Phan J, Rosenthal DI, Fuller CD, Morrison WH, Iyer P, Cabanillas ME. Complete Surgical Resection Following Neoadjuvant Dabrafenib Plus Trametinib in BRAFV600E-Mutated Anaplastic Thyroid Carcinoma. Thyroid 29(8):1036-1043, 2019. e-Pub 2019. PMID: 31319771.
- Ren S, Gaykalova D, Wang JR, Guo T, Danilova L, Favorov A, Fertig E, Bishop J, Khan Z, Flam E, Wysocki PT, DeJong P, Ando M, Liu C, Sakai A, Fukusumi T, Haft S, Sadat S, Califano JA. Discovery and development of differentially methylated regions in human papillomavirus-related oropharyngeal squamous cell carcinoma. Int J Cancer 143(10):2425-2436, 2018. e-Pub 2018. PMID: 30070359.
- Tao Y, Sturgis EM, Huang Z, Wang Y, Wei P, Wang JR, Wei Q, Li G. TGFβ1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy. Clin Cancer Res 24(9):2225-2233, 2018. e-Pub 2018. PMID: 29463556.
- Gama RR, Song Y, Zhang Q, Brown MC, Wang JR, Habbous S, Tong L, Huang SH, O’Sullivan B, Waldron J, Xu W, Goldstein D, Liu G. Body mass index and prognosis in patients with head and neck cancer. Head & Neck 39(6):1226-1233, 2017. e-Pub 2017.
- Wang JR, Habbous S, Espin-Garcia O, Chen D, Huang SH, Simpson C, Xu W, Liu FF, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Goldstein DP, Liu G. Comorbidity and performance status as independent prognostic factors in patients with head and neck squamous cell carcinoma. Head Neck 38(5):736-42, 2016. e-Pub 2016. PMID: 25521753.
- Wang JR, Gramling SJ, Goldstein DP, Cheng D, Chen D, Azad AK, Tse A, Hon H, Chen Z, Mirshams M, Simpson C, Huang SH, Marquez S, O'Sullivan B, Liu FF, Roberts H, Xu W, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Reisman DN, Liu G. Association of two BRM promoter polymorphisms with head and neck squamous cell carcinoma risk. Carcinogenesis 34(5):1012-7, 2013. e-Pub 2013. PMID: 23322154.
- Wang, JR. Parnes LS. Superior semicircular canal dehiscence associated with external, middle, and inner ear abnormalities. The Laryngoscope 120(2):390-393, 2010. e-Pub 2010.
- Wang JR, Yuen HW, Shipp DB, Lin VYW, Chen JM, Nedzelski JM. Cochlear Implantation in Patients with Autoimmune Inner Ear Disease (Including Cogan's Syndrome): A Comparison with Age and Sex Matched Controls. The Laryngoscope 120(12):2478-2483, 2010. e-Pub 2010.
- Douketis J, Wang JR, Cuddy K, Wagler M, Kinnon K, Crowther M. The safety of coadministered continuous epidural analgesia and low-molecular-weight heparin after major orthopedic surgery: assessment of a standardized patient management protocol. Thromb haemost 96(3):387-9, 2006. e-Pub 2006.
Invited Articles
- Cabanillas ME, Ahmed S, Wang JR. Management of Anaplastic and Recurrent Differentiated Thyroid Cancer: Indications for Surgical Resection, Molecular Testing, and Systemic Therapy. Neuroimaging Clin N Am 31(3):359-366, 2021. e-Pub 2021. PMID: 34243870.
- Chasen NN, Wang JR, Gan Q, Ahmed S. Imaging of Cervical Lymph Nodes in Thyroid Cancer. Neuroimaging Clin N Am 31(3):313-326, 2021. e-Pub 2021. PMID: 34243866.
Review Articles
- Hamidi, S, Dadu, R, Zafereo, M, Ferrarotto, R, Wang, RJ, Maniakas, A, Gunn, GB, Lee, A, Spiotto, MT, Iyer, PC, Sousa, LG, Akhave, NS, Ahmed, S, Learned, KO, Lu, C, Lai, SY, Williams, MD, Hosseini, SM, Busaidy, NL, Cabanillas, ME. Initial Management of BRAF V600E-Variant Anaplastic Thyroid Cancer. JAMA Oncology 10(9):1264-1271, 2024. e-Pub 2024. PMID: 38990526.
- Hofmann MC, Kunnimalaiyaan M, Wang JR, Busaidy NL, Sherman SI, Lai S, Zafereo M, Cabanillas ME. Molecular Mechanisms of Resistance to Kinase Inhibitors in Thyroid Cancers. Endocr Relat Cancer 29(11):R173-R190, 2022. e-Pub 2022. PMID: 35975971.
- Head MD, Guidelines Consortium NST, members C, Maniakas A, Jozaghi Y, Zafereo ME, Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader ME, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, CMKL Y, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, De Luna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehdel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Wesson RA, Won A, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY. Head and neck surgical oncology in the time of a pandemic: Subsite-specific triage guidelines during the COVID-19 pandemic. Head Neck 42(6):1194-1201, 2020. e-Pub 2020. PMID: 32342541.
- Higgins KM, Wang JR. State of head and neck surgical oncology research--a review and critical appraisal of landmark studies. Head Neck 30(12):1636-42, 2008. e-Pub 2008. PMID: 18642286.
Other Articles
- Marczyk, VR, Fazeli, S, Dadu, R, Busaidy, NL, Iyer, PC, Hu, MI, Sherman, SI, Hamidi, S, Hosseini, SM, Williams, MD, Ahmed, S, Routbort, MJ, Luthra, R, Roy Chowdhuri, S, San Lucas, FA, Patel, KP, Hong, DS, Zafereo, M, Wang, RJ, Maniakas, A, Waguespack, SG, Cabanillas, ME Erratum. JCO Precision Oncology 9, 2025. PMID: 40632979.
- Kim, ST, Chu, Y, Misoi, MW, Suarez-Almazor, M, Tayar, JH, Lu, H, Buni, M, Kramer, J, Rodriguez, E, Hussain, Z, Neelapu, SS, Wang, RJ, Shah, AY, Tannir, NM, Campbell, M, Gibbons, DL, Cascone, T, Lu, C, Blumenschein, GR, Altan, M, Lim, B, Valero, V, Loghin, ME, Tu, J, Westin, SN, Naing, A, Garcia-Manero, G, Hassan, NA, Tawbi, H, Hwu, P, Oliva, IC, Davies, MA, Patel, SP, Zou, J, Futreal, A, Diab, A, Wang, L, Nurieva, R Author Correction. Nature communications 15(1), 2024. PMID: 38965214.
- Jozaghi Y, Chaudhri A, Zafereo M, Fellman B, Dadu R, Busaidy N, Iyer P, Williams M, Wang J, Roy-Chowdhuri S, Cabanillas M Immunohistochemical Testing versus Next Generation Sequencing for Identification of BRAF V600E Mutations in Clinical Practice for Anaplastic Thyroid Cancer. Thyroid.
Abstracts
- Han AY, Erasmus L, Zafereo ME, Lay SY, Maniakas A, Henderson Y, Zhao X, Wang JR. Mutant Papillary Thyroid Cancer With Loss Of Differentiation Is Characterized By Dysregulation In Metabolic Pathways. Poster presentation awarded first place at the American Head & Neck Society (AHNS) 11th International Conference of Head and Neck Cancer. JAMA Otolaryngology - Head & Neck Surgery, 2023. e-Pub 2023.
- Contrera KJ, Gule-Monroe MK, Cabanillas ME, Hu MI, Busaidy NL, Dadu R, Waguespack SG, Wang JR, Myers J, Grubbs EG, Subbiah V, Williams MD, Zafereo ME. Neoadjuvant selective RET inhibitor for Medullary Thyroid Cancer: A Case Series. American Head and Neck Society 2022 Annual Meeting, 2022. e-Pub 2022.
- Chen X, Wang JR, Henderson Y, Yan Y, Bai S, Kieser R, Hu M, Wang J, Navin N, Lai S, Gao R. Single cell transcriptome analysis maps dynamic epithelial mesenchymal transition and immunological remodeling in thyroid cancer progression. Cancer Research 81(13 Supplement):93, 2021. e-Pub 2021.
- Cabanillas ME, Dadu R, Ferrarotto R, Liu S, Fellman B, Gross ND, Gule-Monroe M, Lu C, Grosu H, Williams MD, Duose DY, Mallampati S, Dervin S, Mckenna EF, Wang JR, Zafereo ME, Busaidy N. Atezolizumab combinations with targeted therapy for anaplastic thyroid carcinoma (ATC). Journal of Clinical Oncology, 2020. e-Pub 2020.
- Wang JR, Cote G, Zafereo ME, Iyer P, Dadu R, Busaidy N, Gross ND, Sturgis E, Ferrarotto R, Lu C, Gunn GB, Myers J, Lai S, Williams M, Cabanillas M. Facilitating rapid precision oncology in anaplastic thyroid cancer: Clinical implications of next generation sequencing (NGS) mutation testing and impact on survival. Journal of Clinical Oncology, 2020. e-Pub 2020.
- Wang JR, Zafereo ME, Dadu R, Ferrarotto R, Busaidy NL, Lu C, Ahmed S, Williams MD, Sturgis EM, Goepfert RP, Gross ND, Lai SY, Gunn GB, Phan J, Rosenthal D, Morrison W, Iyer P, Cabanillas ME. Neoadjuvant targeted therapy followed by surgical resection in BRAFV600E-mutated anaplastic thyroid carcinoma. American Thyroid Association 2018 Annual Meeting, 2018. e-Pub 2018.
- Wang JR, Cote GJ, Zafereo M, Iyer PC, Dadu R, Busaidy NL, Gross ND, Sturgis E, Ferraroto R, Lu C, Gunn GB, Myers J, Lai SY, Williams MD, Cabanillas ME. Facilitating rapid precision oncology in anaplastic thyroid cancer: clinical implications for next generation sequencing (NGS) mutation testing and impact on survival. American Society of Clinical Oncology 2018 Annual Meeting, 2018. e-Pub 2018.
- Wang JR, Espin-Garcia O, Cheng D, Kong Q, Huang SH, Girgis H, Bruce J, Liu FF, O’Sullivan B, Waldron J, Weinreb I, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Goldstein DP, Bairati I, Meyer F, Xu W, Reisman D, Liu G. Germline variants in chromatin remodeling pathways and survival outcomes in patients with head and neck squamous cell carcinoma. Clinician Investigator Trainee Association of Canada & The Canadian Society for Clinical Investigation Annual Meeting, 2014. e-Pub 2014.
- Wang JR, Espin-Garcia O, Chen D, Chen D, Huang SH, Girgis H, Liu F, Xu W, Weinreb, I, Reisman DN, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Goldstein DP, Liu G. Two BRM promoter polymorphisms predict survival outcomes in patients with head and neck squamous cell carcinoma. IFHNOS 5th World Congress/American Head & Neck Society 2014 Annual Meeting, 2014. e-Pub 2014.
- Wang JR, Espin-Garcia O, Chen D, Chen D, Huang SH, O’Sullivan B, Liu F, Xu W, Reisman DN, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Goldstein DP, Liu G. Association of two BRM promoter polymorphisms with oropharyngeal squamous cell carcinoma survival. Poliquin Residents Competition, Canadian Society of Otolaryngology-Head and Neck Surgery, 2013. e-Pub 2013.
- Wang JR, Habbour S, Espin-Garcia O, Chen D, Huang S, Xu W, Liu F, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Goldstein DP, Liu G. Comorbidity and Performance Status Are Independent Prognostic Factors in Head and Neck Squamous Cell Carcinoma Patients. Triological Society Annual Meeting at COSM, 2013. e-Pub 2013.
- Wang JR, Goldstein DP, Liu G. Association of BRM Promoter Polymorphisms with Head and Neck Squamous Cell Carcinoma Risk. 21st Annual Percy Ireland Academic Day, Department of Otolaryngology-Head and Neck Surgery, University of Toronto, 2012. e-Pub 2012.
- Wang JR, Yuen HW, Shipp DB, Lin VYW, Chen JM, Nedzelski JM. Cochlear Implantation in Patients with Autoimmune Inner Ear Disease (Including Cogan's Syndrome): A Comparison with Age and Sex Matched Controls. The Triological Society Combined Sections Meeting, February 4, 2010, 2010. e-Pub 2010.
- Wang JR. Safety of Co-administered Low-Molecular-Weight Heparin and Continuous Epidural Analgesia after Orthopedic Surgery. 46th Annual Meeting of the American Society of Hematology, 2004. e-Pub 2004.
- Wang JR. Anaplastic Thyroid Cancer. 17th International Thyroid Congress.
- Wang JR. Single cell DNA sequencing of BRAF treatment resistant anaplastic thyroid cancer.
- Thennavan A, Tarabichi M, Wu P, Martin M, Lai S, Cabanillas M, Henderson Y, Busaidy N, Zafereo M, Dadu R, Navin N, Wang JR. Single cell DNA sequencing of BRAF treatment resistant Anaplastic Thyroid Cancer. American Association for Cancer Research (AACR) Annual Meeting 2024.
- Wang JR. Integrated Genomic Analysis Identifies Tumor Differentiation Status as a Crucial Determinant of Immune Infiltration and Potential Combinatorial Therapeutic Targets with Immunotherapy in Papillary Thyroid Carcinoma Patients. 2024 American Thyroid Association Annual Meeting.
- Wang JR. Characterization of the genomic landscape of BRAF-, RAS-, and fusion-negative thyroid carcinomas underscores the role of tumor suppressor genes.
Book Chapters
- Cabanillas ME, Wang JR. A Patient with BRAFV600E-Mutated Anaplastic Thyroid Cancer with Metastatic Disease. In: Thyroid Cancer. 1. Springer, 391-396, 2021.
- Cabanillas ME, Ahmed S, Wang JR. Management of Anaplastic and Recurrent Differentiated Thyroid Cancer. In: Thyroid and Parathyroid Imaging. Elsevier, 359, 2021.
- Wang JR. Benign Neoplasms of the Salivary Glands. In: Cummings Otolaryngology Head and Neck Surgery. 7. Elsevier, 2020.
- Wang JR, Bell D, Ferrarotto R, Weber RS, Su S. Malignant Salivary Tumors. Surgery of the Salivary Glands. In: Health Sciences. 1. Elsevier, 286-302, 2019.
- Fernandez V, Oyewumi M, Wang JR. The Head & Neck Exam. In: Essentials of Clinical Examination Handbook. 6, 2010.
- Wang JR, Eskander A, Campisi P. In: Otolaryngology Clerkship Courseware. University of Toronto, 2010.
- Eskander A, Marchie A, Wang JR. Otolaryngology. In: Toronto Notes 2010. 26. University of Toronto, 2010.
- Wang JR. Thrombosis in Children. In: Thrombosis: Your Personal Health Series. Key Porter Books, 2005.
Patient Reviews
CV information above last modified August 22, 2025