Sajad Khazal, MBBCH
Department of Pediatrics, Division of Pediatrics
Present Title & Affiliation
Primary Appointment
Medical Director, Department of Pediatrics Patient Care, Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Professor, Department of Pediatrics Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2002 | College of Medicine/University of Baghdad, Baghdad, IQ, Bachelor of Medicine and Surgery, M.B.Ch.B |
Postgraduate Training
| 2012-2015 | Clinical Fellowship, Pediatric Hematology and Oncology, Children’s Hospital Los Angeles, Los Angeles, California |
| 2011-2012 | Chief Resident, Pediatrics, The Brooklyn Hospital Center, Brooklyn, New York |
| 2009-2011 | Clinical Residency, General Pediatrics - Chief Resident, The Brooklyn Hospital Center, Brooklyn, New York |
| 2008-2009 | Clinical Internship, General Pediatrics, The Brooklyn Hospital Center, Brooklyn, New York |
| 2004-2006 | Clinical Residency, Department of Urology, College of Medicine/University of Baghdad/Medical City/Surgical Subspecialties Hospital, Baghdad |
| 2002-2004 | Clinical Internship, Al-Yarmouk Teaching Hospital, Baghdad |
Licenses & Certifications
| 2017 | The American Board of Pediatric Hematology Oncology |
| 2017 | Texas Medical License |
| 2011 | The American Board of Pediatrics |
| 2011 | California Medical License |
| 2011 | New York Medical License |
| 2011 | Connecticut Medical License |
Experience & Service
Faculty Academic Appointments
Associate Professor, Department of Pediatrics Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - 2023
Assistant Professor, Department of Pediatrics Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - 2022
Assistant Professor, Department of Pediatric Marrow and Blood Cell Transplantation Program, Albert Einstein College of Medicine of Yeshiva University Children’s Hospital at Montefiore, Bronx, NY, 2015 - 2017
Administrative Appointments/Responsibilities
Medical Director, Department of Pediatrics Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2023 - Present
Fellowship Program Director, Department of Pediatrics Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - Present
Chief Pediatric Hematology Oncology Fellow, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, 2014 - 2015
Extramural Institutional Committee Activities
Member of the Safety 365 Operational Priorities Taskforce, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Member, Pediatric Clinical Practice Committee, The University of Texas MD Anderson Cancer Center, 2018 - Present
Member of CARTOX Audit Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - 2020
Member of Focus on Junior Faculty Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - 2022
Editorial Activities
Review Editor, Frontiers in Pediatrics/Pediatric Hematology and Hematologic Malignancies, 2020
Honors & Awards
| 2022 | President's Recognition of Faculty Excellence in Education and Mentorship Advancement, MD Anderson Cancer Center |
| 2010 | Best Resident as a Teacher, The Brooklyn Hospital Center |
| 2009 | Resident of the Year, The Brooklyn Hospital Center |
| 2009 | Best Resident as a Teacher, The Brooklyn Hospital Center |
| 2003 | College Prize, Honor Student, College of Medicine, University of Baghdad |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2020. New Treatments for Sickle Cell Disease. Conference. UT Health. McGovern Medical School. Houston, TX, US.
International Presentations
- 2022. Role of Hematopoietic Stem Cell Transplantation and Immunotherapy in Ewing Sarcoma. Invited. National Cancer Institute, Cairo University & Children's Cancer Hospital Egypt (CCHE; 57357). Alexandria, EG.
Formal Peers
- 2021. Pediatric Grand Rounds “Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia. Update on Indications and Outcomes". Invited. Duarte, CA, US.
- 2016. Grand Rounds. Hematopoietic Stem Cell Transplantation: Cure for Sickle Cell Disease. Invited. Brooklyn, NY, US.
Grant & Contract Support
| Date: | 2013 - 2015 |
| Title: | Ruth L. Kirschstein National Research Service Award |
| Funding Source: | American Institute for Cancer Research (AICR) |
| Role: | Trainee |
| ID: | 5T32CA009659-19 |
Selected Publications
Peer-Reviewed Articles
- Fan, AE, Alqahtani, S, Garnes, ND, Tewari, P, Petropoulos, D, Khazal, SJ, Mahadeo, KM, DePriest, P, Sheikh, IN. Bezlotoxumab as Treatment for Recurrent/Chronic Clostridioides difficile Infection in Pediatric Stem Cell Transplant Recipients. Pediatric Blood and Cancer 72(10), 2025. e-Pub 2025. PMID: 40879561.
- Ragoonanan, D, Abdel-Azim, H, Sharma, A, Bhar, S, McArthur, J, Madden, R, Rahrig, A, Bajwa, R, Wang, J, Sun, V, Wright, M, Lassiter, R, Shoberu, B, Kawedia, J, Khazal, SJ, Mahadeo, KM. Retrospective analysis of veno-occlusive disease/sinusoidal obstruction syndrome in paediatric patients undergoing hematopoietic cell transplantation -a multicentre study. The Lancet Regional Health - Americas 33, 2024. e-Pub 2024. PMID: 38616918.
- Marcoux, C, Saliba, RM, Wallis, W, Khazal, SJ, Ragoonanan, D, Rondon, G, Tewari, P, Popat, UR, Oran, B, Olson, AL, Bashir, Q, Qazilbash, MH, Alousi, AM, Hosing, C, Nieto, Y, Al-Atrash, G, Marin, D, Rezvani, K, Khouri, IF, Srour, S, Champlin, RE, Shpall, E, Kebriaei, P. Incidence and risk factors of early onset VOD/SOS differ in younger vs older adults after stem cell transplantation. Blood Advances 8(5):1128-1136, 2024. e-Pub 2024. PMID: 38266155.
- Pasvolsky, O, Bassett Jr, R, Ghanem, S, Cuglievan, B, Tewari, P, Hosing, C, Srour, S, Ramdial, JL, Mahadeo, KM, Khazal, SJ, Petropoulos, D, Popat, UR, Qazilbash, MH, Kebriaei, P, Champlin, RE, Shpall, E, Nieto, Y. Characteristics and outcomes of children, adolescents and young adults with relapsed/refractory non-hodgkin lymphoma undergoing autologous stem cell transplant. BMC cancer 23(1), 2023. e-Pub 2023. PMID: 38124057.
- Nieto Y, Pasvolsky O, Bassett R, Ghanem S, Cuglievan B, Tewari P, Hosing C, Sr S, Ramdial J, Mahadeo K, Khazal S, Petropoulos D, Popat U, Qazilbash M, Kebriaei P, Champlin R, Shpall E. Characteristics and outcomes of children, adolescents and young adults with relapsed/refractory non-Hodgkin lymphoma undergoing autologous stem cell transplant. Res Sq, 2023. e-Pub 2023. PMID: 36798261.
- Sheikh IN, Alqahtani S, Ragoonanan D, Tewari P, Petropoulos D, Mahadeo KM, Popat U, Shpall EJ, Khazal S. Post-transplant cyclophosphamide after matched sibling and unrelated donor hematopoietic stem cell transplantation in pediatric patients with acute myeloid leukemia. Int J Mol Sci 23(15), 2022. e-Pub 2022. PMID: 35955881.
- Ariagno S, Ragoonanan D, Khazal S, Mahadeo KM, Cisneros GS, Zinter MS, Blacken RA, Mohan G, Lehmann LE, Ferdjallah A, Mara KC, Kohorst MA. Prior COVID-19 infection may increase risk for developing endothelial dysfunction following hematopoietic cell transplantation. Front Oncol 12:1000215, 2022. e-Pub 2022. PMID: 36733348.
- Ragoonanan D, Bhar S, Mohan G, Beltramo F, Khazal S, Hurley C, Andersen C, Margossian S, Neelapu SS, Shpall E, Gutierrez C, Tewari P, Shoberu B, Talleur A, McCall D, Nunez C, Cuglievan B, Tambaro FP, Petropoulos D, Abdel-Azim H, Mahadeo KM. A multicenter study of ICU resource utilization in pediatric, adolescent and young adult patients post CAR-T therapy. Front Oncol 12:1022901, 2022. e-Pub 2022. PMID: 36353531.
- Gibson A, Trabal A, McCall D, Khazal S, Toepfer L, Bell DH, Roth M, Mahadeo KM, Nunez C, Short NJ, DiNardo C, Konopleva M, Issa GC, Ravandi F, Jain N, Borthakur G, Kantarjian HM, Jabbour E, Cuglievan B. Venetoclax for children and adolescents with acute lymphoblastic leukemia and lymphoblastic lymphoma. Cancers (Basel) 14(1), 2021. e-Pub 2021. PMID: 35008312.
- Gaballa MR, Banerjee PP, Milton DR, Jiang X, Ganesh C, Khazal S, Nandivada V, Islam S, Kaplan M, Daher M, Basar R, Alousi A, Mehta RS, Alatrash G, Khouri IF, Oran B, Marin D, Popat UR, Olson AL, Tewari P, Jain N, Jabbour EJ, Ravandi F, Kantarjian HM, Chen K, Champlin RE, Shpall EJ, Rezvani K, Kebriaei P. Blinatumomab maintenance after allogeneic hematopoietic cell transplantation for b-lineage acute lymphoblastic leukemia. Blood. e-Pub 2021. PMID: 34914826.
- Gibson A, Ragoonanan D, Tewari P, Petropoulos D, Rodriguez N, DiNardo C, Mahadeo KM, Khazal S. Non-myeloablative umbilical cord blood transplantation for atypical dyskeratosis congenita. Pediatr Transplant:e14157. e-Pub 2021. PMID: 34626046.
- Ragoonanan D, Khazal S, Abdel-Azim H, McCall D, Cuglievan B, Tambaro FP, Ahmad AH, Rowan CM, Gutierrez C, Schadler K, Li S, Di Nardo M, Chi L, Gulbis AM, Shoberu B, Mireles ME, McArthur J, Kapoor N, Miller J, Fitzgerald JC, Tewari P, Petropoulos D, Gill JB, Duncan CN, Lehmann LE, Hingorani S, Angelo JR, Swinford RD, Steiner ME, Tejada FNH, Martin PL, Auletta J, Choi SW, Bajwa R, Garnes ND, Kebriaei P, Rezvani K, Wierda WG, Neelapu SS, Shpall EJ, Corbacioglu S, Mahadeo KM. Author correction: diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer. Nat Rev Clin Oncol 18(7):468, 2021. e-Pub 2021. PMID: 33731864.
- Khazal S, Kebriaei P. Hematopoietic cell transplantation for acute lymphoblastic leukemia: review of current indications and outcomes. Leuk Lymphoma:1-14. e-Pub 2021. PMID: 34080951.
- Nieto Y, Gruschkus S, Valdez BC, Jones RB, Anderlini P, Hosing C, Popat U, Qazilbash M, Kebriaei P, Alousi A, Saini N, Srour S, Rezvani K, Ramdial J, Barnett M, Gulbis A, Shigle TL, Ahmed S, Iyer S, Lee H, Nair R, Parmar S, Steiner R, Dabaja B, Pinnix C, Gunther J, Cuglievan B, Mahadeo K, Khazal S, Chuang H, Champlin R, Shpall EJ, Andersson BS. Improved outcomes of high-risk relapsed Hodgkin lymphoma patients after high-dose chemotherapy: a 15-year analysis. Haematologica. e-Pub 2021. PMID: 33951890.
- Tambaro FP, Ragoonanan D, Tewari P, Petropoulos D, Aung FM, Mahadeo KM, Khazal S. The role of granulocyte transfusions in optimizing candidacy for chimeric antigen receptor T-cell therapy in patients with treatment-refractory infections. J Pediatr Hematol Oncol. e-Pub 2021. PMID: 33625094.
- Dandoy CE, Rotz S, Alonso PB, Klunk A, Desmond C, Huber J, Ingraham H, Higham C, Dvorak CC, Duncan C, Schoettler M, Lehmann L, Cancio M, Killinger J, Davila B, Phelan R, Mahadeo KM, Khazal S, Lalefar N, Vissa M, Myers K, Wallace G, Nelson A, Khandelwal P, Bhatla D, Gloude N, Anderson E, Huo J, Roehrs P, Auletta JJ, Chima R, Lane A, Davies SM, Jodele S. A pragmatic multi-institutional approach to understanding transplant-associated thrombotic microangiopathy after stem cell transplant. Blood Adv 5(1):1-11, 2021. e-Pub 2021. PMID: 33570619.
- Brown BD, Tambaro FP, Kohorst M, Chi L, Mahadeo KM, Tewari P, Petropoulos D, Slopis JM, Sadighi Z, Khazal S. Immune effector cell associated neurotoxicity (ICANS) in pediatric and young adult patients following chimeric antigen receptor (CAR) T-cell therapy: Can we optimize early diagnosis?. Front Oncol 11:634445, 2021. e-Pub 2021. PMID: 33763368.
- Kohorst MA, Khazal S, Tewari P, Petropoulos D, Mescher B, Wang J, Mahadeo KM, Kelley JM. Transfusion reactions in pediatric and adolescent young adult haematology oncology and immune effector cell patients. EClinicalMedicine 26:100514, 2020. e-Pub 2020. PMID: 32964199.
- Tambaro FP, Khazal S, Nunez C, Ragoonanan D, Tewari P, Petropoulos D, Kebriaei P, Wierda WG, Mahadeo KM. Complete remission in refractory acute lymphoblastic leukemia using blinatumomab after failure of response to CD-19 chimeric antigen receptor T-cell therapy. Clin Case Rep 8(9):1678-1681, 2020. e-Pub 2020. PMID: 32983475.
- Ragoonanan D, Khazal S, Wang J, Payne A, Kohorst M, Harden A, Tewari P, Petropoulos D, Shoberu B, Kebriaei P, Mahadeo KM, Tambaro FP. Improved detection of sinusoidal obstructive syndrome using pediatric-AYA diagnostic criteria and severity grading. Bone Marrow Transplant 56(1):175-184, 2020. e-Pub 2020. PMID: 32665674.
- Harden A, Ragoonanan D, Anildes-Gubman D, McCall D, Faltus K, Featherston S, Shoberu B, Moffet JR, Petropoulos D, Khazal S, Razvi S, Mahadeo KM, Tewari P. Chimeric antigen receptor, teamwork, education, assessment, and management (CAR-TEAM): a simulation-based inter-professional education (IPE) intervention for management of car toxicities. Front Oncol 10:1227, 2020. e-Pub 2020. PMID: 32850365.
- Khazal S, Polishchuk V, Soffer G, Prinzing S, Gill J, Mahadeo KM. Allogeneic hematopoietic stem cell transplantation is associated with cure and durable remission of late-onset primary isolated central nervous system hemophagocytic lymphohistiocytosis. Pediatr Transplant 22(1), 2018. e-Pub 2018. PMID: 29239076.
- Adam E, Kim HN, Gang EJ, Schnair C, Lee S, Lee S, Khazal S, Kosoyan O, Konopleva M, Parekh C, Bhojwani D, Wayne AS, Abdel-Azim H, Heisterkamp N, Kim YM. The PI3Kδ inhibitor idelalisib inhibits homing in an in vitro and in vivo model of B ALL. Cancers (Basel) 9(9), 2017. e-Pub 2017. PMID: 28891959.
- Li L, Qi X, Sun W, Abdel-Azim H, Lou S, Zhu H, Prasadarao NV, Zhou A, Shimada H, Shudo K, Kim YM, Khazal S, He Q, Warburton D, Wu L. Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality. EMBO Mol Med 8(11):1340-1359, 2016. e-Pub 2016. PMID: 27737899.
- Polishchuk V, Khazal S, Berulava G, Roth M, Mahadeo KM. 5-azacitidine monotherapy followed by related haploidentical hematopoietic stem cell transplantation achieves durable remission in a pediatric patient with acute undifferentiated leukemia refractory to high-dose chemotherapy. Pediatr Blood Cancer 63(6):1111-2, 2016. e-Pub 2016. PMID: 26914221.
- Abdel-Azim H, Mahadeo KM, Zhao Q, Khazal S, Kohn DB, Crooks GM, Shah AJ, Kapoor N. Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection. Am J Hematol 90(11):1021-6, 2015. e-Pub 2015. PMID: 26242764.
Review Articles
- Cuglievan, B, Kantarjian, HM, Rubnitz, JE, Cooper, T, Zwaan, CM, Pollard, J, DiNardo, C, Kadia, TM, Guest, E, Short, NJ, McCall, DC, Daver, N, Nunez, CA, Haddad, FG, Garcia, MB, Bhalla, K, Maiti, A, Catueno, S, Fiskus, WC, Carter, BZ, Gibson, A, Roth, M, Khazal, SJ, Tewari, P, Abbas, HA, Bourgeois, W, Andreeff, M, Shukla, N, Truong, D, Connors, JS, Ludwig, JA, Stutterheim, J, Salzer, E, Juul-Dam, KL, Sasaki, K, Mahadeo, KM, Tasian, SK, Borthakur, G, Dickson, S, Jain, N, Jabbour, EJ, Meshinchi, S, Garcia-Manero, G, Ravandi, F, Stein, EM, Kolb, EA, Issa, GC. Menin inhibitors in pediatric acute leukemia. Leukemia 38(10):2073-2084, 2024. e-Pub 2024. PMID: 39179671.
- Cuglievan, B, Connors, JS, He, J, Khazal, SJ, Yedururi, S, Dai, J, Garces, S, Quesada, AE, Roth, M, Garcia, M, McCall, DC, Gibson, A, Ragoonanan, D, Petropoulos, D, Tewari, P, Nunez, CA, Mahadeo, KM, Tasian, SK, Lamble, AJ, Pawlowska, A, Hammond, DE, Maiti, A, Haddad, FG, Senapati, J, Daver, N, Gangat, N, Konopleva, M, Meshinchi, S, Pemmaraju, N. Blastic plasmacytoid dendritic cell neoplasm. Leukemia 37(9):1767-1778, 2023. e-Pub 2023. PMID: 37452102.
- Munir, F, Hardit, V, Sheikh, IN, Alqahtani, S, He, J, Cuglievan, B, Hosing, C, Tewari, P, Khazal, SJ. Classical Hodgkin Lymphoma. International journal of molecular sciences 24(12), 2023. e-Pub 2023. PMID: 37373245.
- He, J, Munir, F, Ragoonanan, D, Zaky, W, Khazal, SJ, Tewari, P, Fueyo-Margareto, J, Gomez-Manzano, C, Jiang, H. Combining CAR T Cell Therapy and Oncolytic Virotherapy for Pediatric Solid Tumors. Immuno 3(1):37-56, 2023. e-Pub 2023.
- Munir F, He J, Connors J, Garcia M, Gibson A, McCall D, Nunez C, Dinh CN, Robusto L, Roth M, Khazal S, Tewari P, Cuglievan B. Translational advances in the treatment of childhood acute lymphoblastic leukemia: narrative review of current and emerging molecular and immunotherapies. Transl Pediatr 12(3):487-502, 2023. e-Pub 2023. PMID: 37035397.
- Ragoonanan D, Sheikh IN, Gupta S, Khazal S, Tewari P, Petropoulos D, Li S, Mahadeo KM. The evolution of chimeric antigen receptor t-cell therapy in children, adolescents and young adults with acute lymphoblastic leukemia. Biomedicines 10(9), 2022. e-Pub 2022. PMID: 36140387.
- Sheikh IN, Elgehiny A, Ragoonanan D, Mahadeo KM, Nieto Y, Khazal S. Management of aggressive non-hodgkin lymphomas in the pediatric, adolescent, and young adult population: an adult vs. pediatric perspective. Cancers (Basel) 14(12), 2022. e-Pub 2022. PMID: 35740580.
- Di Nardo M, Ahmad AH, Merli P, Zinter MS, Lehman LE, Rowan CM, Steiner ME, Hingorani S, Angelo JR, Abdel-Azim H, Khazal S, Shoberu B, McArthur J, Bajwa R, Ghafoor S, Shah SH, Sandhu H, Moody K, Brown BD, Mireles ME, Steppan D, Olson T, Raman L, Bridges B, Duncan CN, Choi SW, Swinford R, Paden M, Fortenberry JD, Peek G, Tissieres P, De Luca D, Locatelli F, Corbacioglu S, Kneyber M, Franceschini A, Nadel S, Kumpf M, Loreti A, Wösten-Van Asperen R, Gawronski O, Brierley J, MacLaren G, Mahadeo KM. Extracorporeal membrane oxygenation in children receiving haematopoietic cell transplantation and immune effector cell therapy: an international and multidisciplinary consensus statement. Lancet Child Adolesc Health 6(2):116-128, 2022. e-Pub 2022. PMID: 34895512.
- Sheikh IN, Ragoonanan D, Franklin A, Srinivasan C, Zhao B, Petropoulos D, Mahadeo KM, Tewari P, Khazal S. Cardiac relapse of acute lymphoblastic leukemia following hematopoietic stem cell transplantation: a case report and review of literature. Cancers (Basel) 13(22), 2021. e-Pub 2021. PMID: 34830969.
- Ragoonanan D, Khazal S, Abdel-Azim H, McCall D, Cuglievan B, Tambaro FP, Ahmad AH, Rowan CM, Gutierrez C, Schadler K, Li S, Di Nardo M, Chi L, Gulbis AM, Shoberu B, Mireles ME, McArthur J, Kapoor N, Miller J, Fitzgerald JC, Tewari P, Petropoulos D, Gill JB, Duncan CN, Lehmann LE, Hingorani S, Angelo JR, Swinford RD, Steiner ME, Hernandez Tejada FN, Martin PL, Auletta J, Choi SW, Bajwa R, Dailey Garnes N, Kebriaei P, Rezvani K, Wierda WG, Neelapu SS, Shpall EJ, Corbacioglu S, Mahadeo KM. Diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer. Nat Rev Clin Oncol 18(7):435-453, 2021. e-Pub 2021. PMID: 33608690.
- Ragoonanan D, Khazal S, Mejia R, Ewing L, Durand JB, Bashoura L, Tayar J, Dailey Garnes N, Petropoulos D, Tewari P, Bhatti M, Ahmad AH, Cortes J, Razvi S, McBeth K, Swinford R, Shoberu B, Waseemuddin W, Chi L, Gill JB, Zaky W, Daw N, Gutierrez C, Tereffe W, Kebriaei P, Rezvani K, Shpall EJ, Champlin RE, Mahadeo KM. Case discussion and literature review: cancer immunotherapy, severe immune-related adverse events, multi-inflammatory syndrome, and severe acute respiratory syndrome coronavirus 2. Front Oncol 11:625707-625707, 2021. e-Pub 2021. PMID: 33614514.
- Khazal S, Kebriaei P. Debate: Transplant is still necessary in the era of targeted cellular therapy for acute lymphoblastic leukemia. Clin Lymphoma Myeloma Leuk 20(11):713-719, 2020. e-Pub 2020. PMID: 32694050.
- Kruse A, Abdel-Azim N, Kim HN, Ruan Y, Phan V, Ogana H, Wang W, Lee R, Gang EJ, Khazal S, Kim YM. Minimal residual disease detection in acute lymphoblastic leukemia. Int J Mol Sci 21(3), 2020. e-Pub 2020. PMID: 32033444.
- Mahadeo KM, Bajwa R, Abdel-Azim H, Lehmann LE, Duncan C, Zantek N, Vittorio J, Angelo J, McArthur J, Schadler K, Chan S, Tewari P, Khazal S, Auletta JJ, Choi SW, Shoberu B, Kalwak K, Harden A, Kebriaei P, Abe JI, Li S, Moffet JR, Abraham S, Tambaro FP, Kleinschmidt K, Richardson PG, Corbacioglu S, Lung Injury PA, Network SI, for Blood TPDWPOTES, Transplantation M. Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement. Lancet Haematol 7(1):e61-e72, 2020. e-Pub 2020. PMID: 31818728.
- Mahadeo KM, Khazal S, Abdel-Azim H, Fitzgerald JC, Taraseviciute A, Bollard CM, Tewari P, Duncan C, Traube C, McCall D, Steiner ME, Cheifetz IM, Lehmann LE, Mejia R, Slopis JM, Bajwa R, Kebriaei P, Martin PL, Moffet J, McArthur J, Petropoulos D, O'Hanlon Curry J, Featherston S, Foglesong J, Shoberu B, Gulbis A, Mireles ME, Hafemeister L, Nguyen C, Kapoor N, Rezvani K, Neelapu SS, Shpall EJ, Lung Injury PA, Network SI. Management guidelines for paediatric patients receiving chimeric antigen receptor T cell therapy. Nat Rev Clin Oncol 16(1):45-63, 2019. e-Pub 2019. PMID: 30082906.
Abstracts
- Kohorst MA, Mahadeo KM, Khazal SJ, Tewari P, Petropoulos D, Mescher B, Kelley JM. Transfusion Reactions in Pediatric and Young Adult Hematopoietic Stem Cell Transplant and Oncology Patients. Transplantation and Cellular Therapy 26(3):S149, 2020. e-Pub 2020.
- Nieto Y, Gruschkus SK, Jones RB, Valdez BC, Timmons M, Hosing C, Anderlini P, Kebriaei P, Popat UR, Qazilbash MH, Alousi AM, Srour SA, Saini N, Ramdial J, Im JS, Shpall EJ, Rezvani K, Gulbis A, Shigle TL, Mahadeo KM, Khazal S, Khouri IF, Dabaja BS, Pinnix CC, Gunther JR, Lee H, Ahmed S, Steiner RE, Iyer SP, Nair R, Parmar S, Cuglievan B, Maadani F, Rondon G, Champlin RE, Andersson BS. Factors Associated with the Improvement of Outcomes of High-Risk Relapsed Hodgkin Lymphoma (HL) Patients Receiving High-Dose Chemotherapy (HDC) and Autologous Stem-Cell Transplantation (ASCT): The MD Anderson Cancer Center Experience. Blood 136(Supplement_1):17-18, 2020. e-Pub 2020.
- Tambaro P, Mahadeo KM, Khazal SJ, Tewari P, Petropoulos D, Slopis JM, Brown BD, Sadighi Z. Immune Effector Cell Associated Neurotoxicity (ICANS) Among Pediatric and AYA Patients: MD Anderson Cancer Center Experience. Transplantation and Cellular Therapy 26(3):S316, 2020. e-Pub 2020.
- Brown B, Mahadeo K, Khazal S, Petropoulos D, Tewari P, Slopis J, Tambaro P, Sadighi AZ. IMMUNE EFFECTOR CELL ASSOCIATED NEUROTOXICITY (ICANS) AMONG PEDIATRIC AND AYA PATIENTS: MD ANDERSON CANCER CENTER EXPERIENCE. Neuro-Oncology 22(Supplement_2):ii116, 2020. e-Pub 2020.
- Harden A, Anildes-Gumba D, Ragoonanan D, McCall D, Khazal S, Featherston S, Faltus K, Shoberu B, Mahadeo KM, Razvi S, Tewari P. SIMULATION BASED EDUCATION FOR THE EVIDENCE BASED MANAGEMENT OF CHIMERIC ANTIGEN RECEPTOR -T CELL RELATED ENCEPHALOPATHY SYNDROME AND CYTOKINE RELEASE SYNDROME. Pediatric Blood & Cancer 66(S2):e27713, 2019. e-Pub 2019.
- Tambaro F, Ragoonanan D, Khazal S, Petropoulos D, Tewari P, Kebriaei P, Wierda W, Kohorst M, Mahadeo K. Sinusoidal Obstructive Syndrome Among Pediatric and Adolescent and Young Adult Patients: Analysis of Pediatric EBMT Diagnostic and Severity Criteria at MD Anderson. Blood 134(Supplement 1):4495-4495, 2019. e-Pub 2019.
- Dandoy CE, Rotz S, Alonso PB, Higham C, Dvorak CC, Duncan C, Schoettler M, Lehmann L, Cancio M, Killinger J, Davila B, Kasprzyk ZA, Phelan R, Mahadeo K, Khazal S, Steiner M, Smith A, Lalefar N, Vissa M, Bhatla D, Gloude N, Anderson E, Huo J, Roehrs P, Auletta J, Davies S, Chima R, Jodele S. Transplant associated thrombotic microangiopathy after transplant: A PBMTC/PALISI multi center collaborative. Pediatric Blood & Cancer 66(S2):e27713, 2019. e-Pub 2019.
- Batth IS, Zaky W, Khatua S, Daw NC, Mahadeo KM, Khazal S, Albert A, Huang W, Chen D, Gill JB, Kleinerman E, Gorlick R, Li S. Automated capture and analysis of circulating tumor cells across different types of tumors in pediatric cancer patients. Cancer Research 79(13 Supplement):1345, 2019. e-Pub 2019.
- McCall D, Featherston S, Curry JO, Khazal S, Mahadeo KM. Immune Effector Cell Transition to Standard of Care: The Children’s Cancer Hospital at MD Anderson Cancer Center Experience. Pediatric Blood & Cancer 65(S1):e27057, 2018. e-Pub 2018.
- Khazal S, Gill J, Gorlick R, Fernandez P, Benard E, and Mahadeo KM. High Dose Chemotherapy Followed By Autologous Stem Cell Rescue for High Risk Soft Tissue Sarcoma: Retrospective Review. Transplantation and Cellular Therapy 24(3):S138, 2018. e-Pub 2018.
- Khazal S, Fernandez P, Benard E, Shoberu B, Manwani D, and Mahadeo KM. Allogeneic Blood and Marrow Transplantation for Pediatric Patients with Sickle Cell Anemia: An Institutional Experience. Blood 130(Supplement 1):4581-4581, 2017. e-Pub 2017.
- Polishchuk V, Khazal S, Soffer G, Prinzing S, Gill J, and Mahadeo KM. Reduced Intensity Conditioning Followed By Allogeneic Hematopoietic Stem Cell Transplantation Resulted in Cure of a 15 Year Old Male with Primary Isolated CNS Late Onset Familial Hemophagocytic Lymphohistiocytosis. Transplantation and Cellular Therapy 22(3):S347 - S348, 2016. e-Pub 2016.
- Khazal S, Manwani D, and Mahadeo KM. Stable Mixed Donor Chimerism after Allogeneic Stem Cell Transplantation Using a Reduced Intensity Conditioning Regimen in a 4 Year Old Boy with Congenital Non Spherocytic Hemolytic Anemia Secondary to Hexokinase Deficiency. Transplantation and Cellular Therapy 22(3):S331, 2016. e-Pub 2016.
Book Chapters
- Khazal, SJ, Kebriaei, P. Allogeneic Hematopoietic Cell Transplantation for Patients With Acute Lymphoblastic Leukemia, 217-232, 2023.
- Khazal S, Ragoonanan D, Mahadeo AK. Care of the Critically Ill Pediatric Hematopoietic Cell Transplant Patient. In: Pediatric Critical Care Study Guide 2nd edition. 2nd. Springer International Publishing, 2021.
- Khazal, S, Mahadeo, K. Chimeric Antigen Receptor (CAR) T cell therapy. In: Pediatric Oncologic Critical Care. Springer, Cham, pp 2035-2047, 2018.
- Khazal S, Galvez Silva JR, Thakar M, Margolis D. Bone Marrow Failure. In: Bone Marrow Failure. In: Critical Care of The Pediatric Immunocompromised Hematology/Oncology Patient: An Evidence-Based Guide. Springer International Publishing AG, Cham, 2018.
- Gang E, Hinh C, Khazal S, Kim Y. Molecular Pathogenesis of ALL. In: Contemporary Management of Acute Lymphoblastic Leukemia. Jp Medical Ltd, 2014.
Letters to the Editor
- Okeleji, O, Khazal, SJ, Mahadeo, KM, Ragoonanan, D, Rodriguez, NI, DiNardo, C, Connors, JS, Petropoulos, D, Tewari, P, Sheikh, IN. Allogeneic Hematopoietic Stem Cell Transplant for an Unknown Inherited Bone Marrow Failure Syndrome With a Novel Compound Heterozygous Mutation. Pediatric Blood and Cancer 72, 2025.
- Sheikh, IN, Uwaezuoke, D, Okeleji, O, Quesada, AE, Herzog, CE, Ragoonanan, D, Tewari, P, Petropoulos, D, McCall, DC, Nunez, CA, Roth, M, Cuglievan, B, Khazal, SJ. Treatment of a Pediatric Patient with Core Binding Factor Acute Myeloid Leukemia Post-Cytotoxic Therapy With Cytarabine, Daunorubicin, and Gemtuzumab Followed by Stem Cell Transplantation. Pediatric Blood and Cancer 72, 2025.
- Ragoonanan D, Tambaro FP, Khazal SJ, Tewari P, Petropoulos D, Champlin R, Mahadeo KM. Cytokine release syndrome and complete remission of extra medullary acute lymphoblastic leukemia of the breast with CAR-T and radiation therapy. Pediatr Blood Cancer 68: e28839, 2021.
- Kohorst MA, Nunez CA, Tewari P, Petropoulos D, Mahadeo KM, Neelapu SS, Shpall EJ, Khazal S. Primary mediastinal large B-cell lymphoma in paediatric and adolescent patients: emerging questions in the era of immunotherapy. Br J Haematol 190: e114-e117, 2020.
- Khazal S, Ragoonanan D, Hosing C, Williams L, Medeiros LJ, Mahadeo KM, Thompson PA. Epstein - Barr virus specific cytotoxic T lymphocytes for the treatment of severe epstein-barr virus mucocutaneous ulcer. Br J Haematol 189: e33-e36, 2020.
- Khazal S, Polishchuk V, Manwani D, Gallagher PG, Prinzing S, Mahadeo KM. Allogeneic bone marrow transplantation for treatment of severe hemolytic anemia attributable to hexokinase deficiency. Blood 128: 735-7, 2016.
- Khazal S, Abdel-Azim H, Kapoor N, Mahadeo KM. Overcoming psychosocial and developmental barriers to blood and marrow transplantation (BMT) in an adolescent/young adult (AYA) transgender patient with chronic myelogenous leukemia. Pediatric Hematology and Oncology 31: 765-767, 2014.
- Hsieh YT, Gang EJ, Shishido SN, Kim HN, Pham J, Khazal S, Osborne A, Esguerra ZA, Kwok E, Jang J, Bonig H, Biediger RJ, Vanderslice P, Kim YM. Effects of the small-molecule inhibitor of integrin α4, TBC3486, on pre-B-ALL cells. Leukemia 28: 2101-2104, 2014.
Patient Reviews
CV information above last modified March 31, 2026