Salvador Alonso Martinez, MD

Peer-Reviewed Articles

1. Alonso Martinez, S, Chu, K, Granowsky, E, Rabanales, VS, Parsons, MJ, Gunasinghe, H, Shia, J, Yaeger, R, Dow, LE. Concurrent genetic and non-genetic resistance mechanisms to KRAS inhibition in colorectal cancer. Cancer cell 44(7):1368-1380.e8, 2026. e-Pub 2026. PMID: 42167227.
2. Villanueva, JW, Kwong, L, Han, T, Alonso Martinez, S, Shanahan, MT, Kanke, M, Dow, LE, Danko, CG, Sethupathy, P. Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival. BMC genomics 23(1), 2022. e-Pub 2022. PMID: 36457077.
3. Alonso Martinez S, Segal NH, Cercek A, Yaeger R, Stadler Z, Kemeny NE, Nusrat M, Shahrokni A, Connell L, Saltz LB. Simplified Graded Infusion Strategy for Mitigation of Oxaliplatin Hypersensitivity. Clin Colorectal Cancer 21(2):149-153, 2022. e-Pub 2022. PMID: 35125319.
4. Chang YT, Hernandez D, Alonso S, Gao M, Su M, Ghiaur G, Levis MJ, Jones RJ. Role of CYP3A4 in bone marrow microenvironment-mediated protection of FLT3/ITD AML from tyrosine kinase inhibitors. Blood Adv 3(6):908-916, 2019. e-Pub 2019. PMID: 30898762.
5. Alonso S, Hernandez D, Chang YT, Gocke CB, McCray M, Varadhan R, Matsui WH, Jones RJ, Ghiaur G. Hedgehog and retinoid signaling alters multiple myeloma microenvironment and generates bortezomib resistance. J Clin Invest 126(12):4460-4468, 2016. e-Pub 2016. PMID: 27775549.
6. Alonso S, Su M, Jones JW, Ganguly S, Kane MA, Jones RJ, Ghiaur G. Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes. Oncotarget 6(17):14905-12, 2015. e-Pub 2015. PMID: 25915157.
7. Su M, Alonso S, Jones JW, Yu J, Kane MA, Jones RJ, Ghiaur G. All-Trans Retinoic Acid Activity in Acute Myeloid Leukemia: Role of Cytochrome P450 Enzyme Expression by the Microenvironment. PLoS One 10(6):e0127790, 2015. e-Pub 2015. PMID: 26047326.

Review Articles

1. Alonso S, Dow LE. Engineering chromosome rearrangements in cancer. Dis Model Mech 14(9), 2021. e-Pub 2021. PMID: 34585724.
2. Alonso S, Saltz L. The Landmark Series: Chemotherapy for Non-Metastatic Colon Cancer. Ann Surg Oncol 28(2):995-1001, 2021. e-Pub 2021. PMID: 33230749.
3. Alonso S, Yilmaz OH. Nutritional Regulation of Intestinal Stem Cells. Annu Rev Nutr 38:273-301, 2018. e-Pub 2018. PMID: 29799767.
4. Alonso S, Jones RJ, Ghiaur G. Retinoic acid, CYP26, and drug resistance in the stem cell niche. Exp Hematol 54:17-25, 2017. e-Pub 2017. PMID: 28754309.

Other Articles

1. Bild, AH, Sangar, MC, McQuerry, JA, Ideker, T, Kopetz, S, Carey, L, Nath, A, Marcus, D, Regier, AA, Rashid, N, Barzilay, R, Winer, EP, Salgia, R, Malhotra, J, Gentles, A, Buetow, K, Mahmood, F, Markman, DW, Eddy, J, Afkhami, M, Alfaro-Munoz, KD, Alonso Martinez, S, Alpert, K, Anampa, J, Bafna, V, Balic, M, Balko, JM, Barzilay, R, Bates, S, Bekaii-Saab, T, Bernard-Pagan, V, Bild, A, Boland, GM, Borad, MJ, Buetow, K, Buhle, L, Burns, R, Cannon, TL, Carey, LA, Castelnovo, LF, Chen, R, Cianfrocca, M, Clark, A, Hamilton, SR, Kopetz, S, Maru, DM, Menter, DG, Raghav, KS, Rai, K, Tayob, N The ADAPT learning cancer treatment system. Cancer cell 44(3):449-454, 2026. PMID: 41512871.
2. Alonso Martinez, S, Raghav, KS, Morris, VK, Alfaro-Munoz, KD, Bekaii-Saab, T, Cannon, TL, Corcoran, RB, Duesbery, N, George, M, Hsu, D, Lieu, C, Maitra, A, Maru, DM, McQuerry, JA, Menter, DG, Mizrahi, JD, Ng, K, Parikh, AR, Rai, K, Sangar, MC, Shaw, KR, Shen, JP, Strickler, JH, Feehan, AD, Tam, A, Vetere, G, Yaeger, R, Yuan, Y, Shen, X, Bild, A, Kopetz, S Framework for cancer evolution profiling and interception in colorectal cancer. Cancer cell 44(3):455-459, 2026. PMID: 41512869.

Letters to the Editor

1. Hernandez D, Palau L, Norsworthy K, Anders NM, Alonso S, Su M, Petkovich M, Chandraratna R, Rudek MA, Smith BD, Jones RJ, Ghiaur G. Overcoming microenvironment-mediated protection from ATRA using CYP26-resistant retinoids. Leukemia 34: 3077-3081, 2020.