Samuel A. Shelburne, M.D., Ph.D.
Department of Infectious Diseases, Infection Control, and Employee Health, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Professor (Joint appointment), Department of Genomic Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX
Deputy Chair, Department of Infectious Diseases, The University of Texas MD Anderson Cancer Center, Houston, TX
Member, Department of Graduate Faculty, The University of Texas Graduate School of Biomedical Science at Houston, Houston, TX
Clinical Assistant Professor, Texas A&M Health Science Center of Medicine, College Station, TX
Adjunct Assistant Professor, Baylor College of Medicine, Houston, TX
Affiliate Member, Methodist Hospital Research Institute, Houston, TX
Dual/Joint/Adjunct Appointment
SHP Affiliate Graduate Faculty Member, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX
Member, Department of Graduate Faculty, The University of Texas Graduate School of Biomedical Science at Houston, Houston, TX
Clinical Assistant Professor, Texas A&M Health Science Center of Medicine, College Station, TX
Adjunct Assistant Professor, Baylor College of Medicine, Houston, TX
Affiliate Member, Methodist Hospital Research Institute, Houston, TX
Education & Training
Degree-Granting Education
| 2011 | Baylor College of Medicine, Houston, Texas, US, Ph.D. in Clinical Investigation |
| 2005 | Baylor College of Medicine, Houston, Texas, US, M.S. in Clinical Investigation |
| 1998 | University of Texas Medical Branch, Galveston, Texas, US, MD |
| 1994 | Princeton University, Princeton, New Jersey, US, AB in History of Art |
Postgraduate Training
| 2002-2005 | Clinical Fellowship, Infectious Diseases, Baylor College of Medicine, Houston, Texas |
| 2001-2002 | Chief Resident, Baylor College of Medicine, Houston, Texas |
| 1998-2001 | Clinical Internship, Internal Medicine, Baylor College of Medicine, Houston, Texas |
| 1998-2001 | Clinical Residency, Internal Medicine, Baylor College of Medicine, Houston, Texas |
Licenses & Certifications
| 2004 | American Board of Internal Medicine, Infectious Diseases |
| 2002 | American Board of Internal Medicine |
| 2001 | Medical |
Experience & Service
Faculty Academic Appointments
Associate Professor, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2018
Assistant Professor, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2008 - 2012
Assistant Professor, Baylor College of Medicine, Houston, TX, 2005 - 2008
Chief Medical Resident, Baylor College of Medicine, Houston, TX, 2001 - 2002
Administrative Appointments/Responsibilities
Deputy Chair, Department of Infectious Diseases, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - Present
Director, Genomic Infectious Diseases Research, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - Present
Other Professional Positions
Steering Committee, Antibiotic Resistance Leadership Group, Durham, NC, 2019 - Present
Steering Committee, Gulf Coast Consortium on Antimicrobial Resistance, Houston, TX, 2016 - Present
Leader, Microbiome Working Group, MD Anderson Cancer Center, Houston, TX, 2015 - Present
Organizer, MD Anderson Infectious Diseases Faculty Research Meeting, Houston, TX, 2011 - Present
Organizer, MD Anderson Infectious Diseases Journal Club, Houston, TX, 2010 - 2013
Interviewer, MD Anderson Infectious Diseases Fellowship, Houston, TX, 2008 - Present
Research Postdoctoral Fellow, James M. Musser Laboratory, The Methodist Hospital, Houston, TX, 2003 - 2005
Extramural Institutional Committee Activities
Member, Faculty Recruitment Panel, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Faculty Diversity Panel, The University of Texas MD Anderson Cancer Center, 2021 - 2023
Member, Department of Cardiology Search Committee, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Co-Director, Microbiome Core Facility, The University of Texas MD Anderson Cancer Center, 2018 - Present
Member, Clinical Research Advisory Committee, The University of Texas MD Anderson Cancer Center, 2017 - 2020
Member, Multidisciplinary Research Advisory Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, INTEREST Review Committee, The University of Texas MD Anderson Cancer Center, 2015 - Present
Chair, Division of Internal Medicine Research Committee, The University of Texas MD Anderson Cancer Center, 2013 - 2015
Member, Basic Study Section Review Committee-Institutional Research Grants Program, The University of Texas MD Anderson Cancer Center, 2011 - 2013
Vice-Chair, Division of Internal Medicine Research Committee, The University of Texas MD Anderson Cancer Center, 2011 - 2013
Member, Scientific Review Committee, The University of Texas MD Anderson Cancer Center, 2011 - 2021
Chair, Department of Infectious Diseases Basic Science Faculty Search Committee, The University of Texas MD Anderson Cancer Center, 2011 - Present
Member, Division of Internal Medicine Research Committee, The University of Texas MD Anderson Cancer Center, 2010 - 2011
Editorial Activities
Member of Editorial Review Board, Antimicrobial Agents and Chemotherapy, 2015 - Present
Member of Editorial Review Board, Journal of Infection, 2006 - Present
Honors & Awards
| 2019 | Outstanding Clinical Research Mentor, MD Anderson School of Health Professions |
| 2018 | Cyrus Scholar Award for Outstanding Basic Research, Division of Internal Medicine, MD Anderson Cancer Center |
| 2015 | Fellow, Infectious Diseases Society of America |
| 2015 | Finalist, Robert M. Chamberlain Distinguished Mentor Award, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center |
| 2014 - 2023 | R. Lee Clark Fellow, MD Anderson Cancer Center |
| 2013 | Cyrus Scholar Award Winner, MD Anderson Cancer Center |
| 2013 | Teaching Faculty of the Year Infectious Disease Fellowship Program, Baylor College of Medicine |
| 2011 | Basic Research Outstanding Poster Award, Division of Internal Medicine Research Symposium, MD Anderson Cancer Center |
| 2009 | Semi-Finalist, Cyrus Award, Division of Internal Medicine Research Retreat, MD Anderson Cancer Center |
| 2007 - 2011 | Travel Award, American Society for Clinical Investigation/American of Physicians Joint Meeting in Chicago |
| 2005 | Outstanding Research Award, Baylor College of Medicine |
| 2000 - 2002 | Baylor Graduate Medical Education Resident Teaching Award, Baylor College of Medicine |
| 1999 - 2000 | Outstanding Clinical Research Award, Baylor College of Medicine |
| 1999 - 2000 | Outstanding Resident Educator, Baylor College of Medicine |
| 1996 | Elected to AΦA as Junior Year Medical Student, University of Texas Medical Branch |
Professional Memberships
Selected Presentations & Talks
National Presentations
- 2019. Infectious Complications in Cancer Patients. Conference. Infectious Complications in Cancer Patients. Houston, TX, US.
- 2018. Infectious Complications in Cancer Patients. Conference. Infectious Complications in Cancer Patients. Houston, TX.
- 2017. The Impact of the Microbiome on Infectious Outcomes in Patients with Hematologic Malignancy. Conference. The Impact of the Microbiome on Infectious Outcomes in Patients with Hematologic Malignancy. Houston, TX, US.
- 2017. Infectious Complications in Cancer Patients. Conference. Infectious Complications in Cancer Patients. Houston, TX, US.
- 2017. Clinical Impact of Bacterial Whole Genome Sequencing: Lessons from the Front Line. Conference. Whole Genome Sequencing and Infectious Diseases Conference. Austin, TX, US.
- 2016. Insights into the Mycobiome of Patients with Acute Leukemia. Conference. Insights into the Mycobiome of Patients with Acute Leukemia. Boston, MA, US.
- 2015. Viridans group streptococci: Can the Clinical Microbiology Laboratory help?. Conference. Viridans group streptococci: Can the Clinical Microbiology Laboratory help?. San Diego, CA, US.
- 2014. Documentation of an Invasive Phenotype of Group A Streptococcus Arising During Human Infection Using Whole Genome Sequencing of Multiple Clinical Isolates From the Same Patient. Conference. Genomic Medicine Conference. Houston, TX, US.
- 2014. Integration of host genomics into infectious risk in AML patients: challenges and opportunities. Conference. ASM Event. Washington, DC, US.
- 2013. Personalized Cancer Therapy: A Primer on Molecular Genetics. Conference. Personalized Cancer Therapy: A Primer on Molecular Genetics. Houston, TX, US.
- 2005. Role of Maltodextrin Binding in Group A Streptococcus Pharyngitis. Conference. Role of Maltodextrin Binding in Group A Streptococcus Pharyngitis. Hamilton, MT, US.
- 2005. Role of Maltodextrin Binding in Group A Streptococcus Pharyngitis. Conference. Role of Maltodextrin Binding in Group A Streptococcus Pharyngitis. Toronto, US.
International Presentations
- 2022. Challenging Antimicrobial Resistance Cases in Immunocompromised Patients. Conference. Universidad El Bosque. Bogotá D.C, CO.
- 2016. The Next-Generation of Group A Streptococcal Research: More than Next-Generation Sequencing. Conference. Keynote Speaker. Toronto Invasive Bacterial Diseases Network-Education Day. Toronto, CA.
Formal Peers
- 2022. 5th Annual Texas Medical Center Antimicrobial Resistance and Stewardship Conference. Invited. Houston, TX, US.
- 2018. Genomic approaches to Infectious Diseases. Invited. Houston, TX, US.
- 2018. Genomic Approaches to Infectious Diseases Research. Invited. Dallas, TX, US.
- 2018. Identification of Clinically Significant Antimicrobial Resistance Genes in the Commensal Microbiota. Invited. Houston, TX, US.
- 2018. Insights into Infectious Diseases Generated by Genomic Approaches: Lessons from the Front Line. Invited. Houston, TX, US.
- 2017. Can Antimicrobial Stewardship Improve the Treatment of Cancer?. Visiting. Houston, TX, US.
- 2017. Clinical Impact of Bacterial Whole Genome Sequencing: Lessons from the Front Line. Invited. Austin, TX, US.
- 2017. Update and Future Directions of Microbiome Research in Leukemia Patients. Visiting. Houston, TX, US.
- 2017. Antimicrobial Resistance in Cancer Patients: A Perfect Storm. Invited. Houston, TX, US.
- 2016. How Large Scale Whole Genome Analyses of Bacteria are Changing our Understanding of Human Infectious Diseases. Invited. Houston, TX, US.
- 2016. Infectious Diseases and Personalized Medicine: A Return to Our Roots. Visiting. Houston, TX, US.
- 2015. What next-generation sequencing has taught us about streptococcal disease in humans: from microbial pathogenesis to vaccine implications. Visiting. Houston, TX, US.
- 2015. Novel insights into Group A Streptococcus host-pathogen interaction in the human oropharynx. Invited. Houston, TX, US.
- 2015. 8th Annual Catherine Mulvale, Surviving Strep-Strategies for Life Lecture. Invited. Toronto, Canada, CA.
- 2015. Harnessing the Microbiome to Improve the Health of the Cancer Patient. Visiting. Houston, TX, US.
- 2015. Harnessing the Microbiome to Improve the Care of the Cancer Patient. Visiting. Houston, TX, US.
- 2015. Using Molecular Epidemiology to Investigate Streptococcal Infections. Invited. Houston, TX, US.
- 2014. Analysis of Fluoroquinolone Resistance In Viridans Group Streptococci Causing Invasive Disease in Cancer Patients. Invited. Houston, US.
- 2014. Elucidation of the Changes in the Microbiome and its Role in Septicemia and Neutropenic Fever in Acute Myelogenous Leukemia Patients Undergoing Induction Remission Chemotherapy. Visiting. Houston, TX, US.
- 2013. Towards a Molecular Understanding of Streptococcal Pathogenesis. Invited. Houston, TX, US.
- 2012. How Phosphorylation Pathways Impact Streptococcal Pathogenesis. Invited. Durham, NC, US.
- 2012. New Insight on Streptococcal Infections. Visiting. Houston, TX, US.
- 2012. Towards a Molecular Understanding of Streptococcal Pathogenesis. Invited. Houston, TX, US.
- 2011. Using Single-Nucleotide Polymorphisms to Study Streptococcal Pathogenesis. Invited. Houston, TX, US.
- 2011. Identification and Characterization of Viridans Group Streptococci Causing Invasive Human Infection. Invited. Houston, TX, US.
- 2011. New Insights into Streptococcal Pathogenesis. Keynote Speaker. Invited. Galveston, TX, US.
- 2011. New Insights into the Molecular Basis of Streptococcal Pathogenesis. Invited. Houston, TX, US.
- 2011. New insights into the molecular basis of streptococcal pathogenesis. Invited, US.
- 2011. New insights in the the Epidemiology and the Pathogenesis of Streptococcal Infection. Visiting, US.
- 2011. Using single nucleotide polymorphisms to study streptococcal pathogenesis. Invited. Houston, TX, US.
- 2011. New insights into streptococcal pathogenesis. Invited. Galveston, TX, US.
- 2008. Update on Methicillin-Resistant Staphylococcus Aureus. Invited. Houston, TX, US.
- 2008. Novel avenues of investigation of group A Streptococcus pathogenesis. Invited. Houston, TX, US.
- 2008. Link Between Central Metabolism and Virulence in group A Streptococcus. Invited. Houston, TX, US.
- 2008. Antimicrobial Resistance in Staphylococci and Streptococci. Invited. Houston, TX, US.
- 2008. Methicillin-resistant Staphylococcus aureus: not just for hospitals. Visiting. Houston, TX, US.
- 2008. Methicillin-resistant Staphylococcus aureus: not just for hospitals. Invited. Houston, TX, US.
- 2008. Link between central metabolism and virulence in group A Streptococcus. Visiting, US.
- 2008. Novel avenues of investigation of group A Streptococcus pathogenesis. Visiting, US.
- 2008. Update on methicillin-resistant Staphylococcus Aureus. Visiting, US.
- 2008. Antimicrobial resistance in staphylococci and streptococci. Visiting, US.
- 2007. Recent Developments in the Epidemiology and Treatment of Gram-Positive Pathogens. Invited. Galveston, TX, US.
- 2007. Skin and soft tissue infections. Invited. Houston, TX, US.
- 2007. Skin and soft tissue infections. Visiting, US.
- 2007. New Insights into the pathogenesis of Group A Streptococcus Pharyngitis. Visiting, US.
- 2007. New insights in the treatment of gram-positive infections. Visiting, US.
- 2006. HIV/AIDS. Invited. Houston, TX, US.
- 2006. The Role of Polysaccharide Utilization in group A Streptococcus pharyngitis. Invited. Houston, TX, US.
- 2006. HIV for the Primary Care Physician. Invited. Houston, TX, US.
- 2006. Discussant, Clinical Pathologic Case Conference. Invited. Houston, TX, US.
- 2006. The role of polysaccharide utilization in group A Stretococcus pharyngitis. Visiting, US.
- 2006. HIV for the Primary Care Physician. Visiting, US.
- 2006. Analysis of Group A Streptococcus-saliva interaction. Visiting, US.
- 2006. Outpatient Management of HIV. Visiting, US.
- 2006. Chronic Fungal sinusitis. Invited. Houston, TX, US.
- 2005. Role of Maltodextrin binding in group A Streptococcus pharyngitis. Visiting, US.
- 2005. Group A Streptococcus Host-Pathogen Interaction in the Human Oropharynx. Visiting. Houston, TX, US.
- 2005. Group A Streptococcus Host-Pathogen Interaction in the Human Oropharynx. Invited. Houston, TX, US.
- 2005. Group A Streptococcus-saliva interaction. Visiting. Houston, TX, US.
- 2005. New Insights into Group A Streptococcus Pharyngitis. Visiting, US.
- 2005. Analysis of Group A Streptococcis-saliva interaction. Visiting, US.
- 2003. Proposal for a national trial for the prevention of immune reconstitution inflammatory syndrome. Invited. Miami, FL, US.
Grant & Contract Support
| Date: | 2024 - 2026 |
| Title: | Delineation of mechanisms underlying response regulator activation in group A Streptococcus |
| Funding Source: | NIH/NIAID |
| Role: | PI |
| ID: | 1R21AI177931-01A1 |
| Date: | 2022 - 2024 |
| Title: | NO TITLE PROVIDED |
| Funding Source: | NIH/NIAID |
| Role: | PI |
| ID: | R21AI168665 |
| Date: | 2022 - 2027 |
| Title: | Mechanisms and Impact of Anti-bacterial Resistance in Stenotrophomonas maltophilia |
| Funding Source: | University of North Carolina at Chapel Hill/NIH |
| Role: | Principal Investigator-MDACC |
| Date: | 2021 - 2024 |
| Title: | Impact of regulatory cross-talk on the pathophysiology of emergent acapsular group A streptococcus |
| Funding Source: | NIH/NIAID |
| Role: | PI |
| ID: | R21AI156202 |
| Date: | 2021 - 2023 |
| Title: | Role of β-lactamase encoding gene amplification in the development of non-carbapenemase producing, carbapenem-resistant Enterobacteriaceae |
| Funding Source: | NIH/NIAID |
| Role: | Principal Investigator-MDACC |
| ID: | 1R21AI151536-01A1 |
| Date: | 2021 - 2024 |
| Title: | Defining novel mechanisms of clonal emergence in Group A Streptococcus |
| Funding Source: | NIH/NIAID |
| Role: | PI |
| ID: | R21AI159059 |
| Date: | 2020 - 2025 |
| Title: | Dynamics of colonization and infection by multidrug-resistant pathogens in immunocompromised and critically ill patients (DYNAMITE) – CORE - FUSE |
| Funding Source: | NIH/NIAID |
| Role: | Principal Investigator-MDACC |
| ID: | 1P01AI152999-02 |
| Date: | 2020 - 2025 |
| Title: | Dynamics of colonization and infection by multidrug-resistant pathogens in immunocompromised and critically ill patients (DYNAMITE) – Project 2 |
| Funding Source: | NIH/NIAID |
| Role: | Principal Investigator-MDACC |
| ID: | 1P01AI152999-02 |
| Date: | 2019 - 2021 |
| Title: | Antibacterial Resistance Leadership Group (ARLG) |
| Funding Source: | NIH/NIAID |
| Role: | Scientific Expert |
| ID: | 5UM1AI104681 |
| Date: | 2019 - 2024 |
| Title: | Novel analysis of association between microbiome and treatment infection in AML |
| Funding Source: | NIH/NIAID |
| Role: | Co-I |
| ID: | R01AI143886 |
| Date: | 2019 - 2024 |
| Title: | Dissection of regulatory system mutations impacting acapsular group A streptococcal virulence |
| Funding Source: | NIH/NIAID |
| Role: | PI |
| ID: | R01AI144165 |
| Date: | 2019 - 2023 |
| Title: | Identifying Risk Factors for Antibiotic Resistance via Integration of Epidemiology and Metagenomics |
| Funding Source: | NIH/NIAID |
| Role: | Mentor |
| ID: | 1K01AI143881 |
| Date: | 2018 - 2020 |
| Title: | Impact of a novel emm-enn gene fusion event on epidemic behavior of group A streptococcus |
| Funding Source: | NIH/NIAID |
| Role: | Co-PI |
| ID: | 1R21AI142126-01 |
| Date: | 2018 - 2020 |
| Title: | Composition and temporal changes of the oral microbiome in head and neck cancer patients at high risk for oral mucositis |
| Funding Source: | NIH/NIDCR |
| Role: | Co-I |
| ID: | DE026837 |
| Date: | 2018 - 2020 |
| Title: | Novel mechanisms of emergence of hypervirulent group A Streptococcus |
| Funding Source: | NIH/NIAID |
| Role: | PI |
| ID: | R21AI142126-01 |
| Date: | 2018 - 2020 |
| Title: | Detection and Kinetics of clinically relevant antibiotic resistance in the commensal microbiota |
| Funding Source: | NIH/NIAID |
| Role: | Co-I |
| ID: | R21 AI33301 |
| Date: | 2017 - 2019 |
| Title: | Development of novel methodology to associate microbiome data with clinical outcomes |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | 1R03CA216030-01A1 |
| Date: | 2016 - 2021 |
| Title: | Role of response regulator phosphorylation in group A streptococcal pathogenesis |
| Funding Source: | NIH/NIAID |
| Role: | Investigator |
| ID: | R01AI125292 |
| Date: | 2015 - 2017 |
| Title: | Role of the Gastrointestinal Microbiome in the Care of the Cancer Patient, Multi-disciplinary research project |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Co-I |
| Date: | 2014 - 2017 |
| Title: | R.Lee Clark Fellow |
| Funding Source: | MD Anderson Cancer Center |
| Role: | PI |
| Date: | 2013 - 2017 |
| Title: | Integrated program in toxicity genomics in patients treated for acute Myelogenous Leukemia/Myelodysplastic Syndrome |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Co-I |
| Date: | 2011 - 2016 |
| Title: | Contribution of catabolite control protein A to group A streptococcal virulence |
| Funding Source: | NIH/NIAID |
| Role: | Principal Investigator-MDACC |
| ID: | R01 AI089891 |
| Date: | 2011 - Present |
| Title: | Optimizing management of enterococcal bacteriuria |
| Funding Source: | Veterans Administration |
| Role: | Co-I |
| Date: | 2010 - 2012 |
| Title: | Structure-function analysis of the streptococcal control of virulence regulator |
| Funding Source: | Institutional Research Grant |
| Role: | Principal Investigator-MDACC |
| Date: | 2009 - 2011 |
| Title: | The structural and functional basis for the contribution of catabolite protein A to group A streptococcal pathogenesis |
| Funding Source: | American Heart Association |
| Role: | Principal Investigator-MDACC |
| Date: | 2006 - 2010 |
| Title: | Analysis of Group A Streptococcus-saliva interaction |
| Funding Source: | NIH/NIAID |
| Role: | Principal Investigator-MDACC |
| ID: | K08-AI064564 |
| Date: | 2005 - 2009 |
| Title: | The Role of polysaccharide utilization in group A Streptococcus host-pathogen interaction |
| Funding Source: | American Heart Association |
| Role: | Principal Investigator-MDACC |
| ID: | 0765115Y |
| Date: | 2005 - 2006 |
| Title: | Analysis of Group A Streptococcus-saliva interaction. Mentored Clinical Investigator Career Development Award |
| Funding Source: | NIH/NIDA |
| Role: | Principal Investigator-MDACC |
| ID: | K08 AI 064564 |
| Date: | 2003 - 2005 |
| Title: | Institutional Research Training Grant |
| Funding Source: | NIH/NIAID |
| Role: | Trainee |
| Date: | 2002 - 2003 |
| Title: | Incidence and risk factors for immune reconstitution syndrome in HIV-infected patients |
| Funding Source: | Bristol-Meyers Squibb (BMS) HIV Fellow Grant |
| Role: | Principle Investigator-BCM |
| Title: | Hypervirulent Group A Streptococcus Emergence in an Acapsular Background is Associated with Marked Remodeling of the Bacterial Cell Surface |
| Funding Source: | Cyrus Award for Outstanding Basic Science Project |
| Role: | PI |
| Title: | Structure-function analysis of the role of the CcpA-HPr-HprK/P axis in group A streptococal pathogenesis as a prelude to novel antimicrobial drug discovery, Challenge Grant |
| Funding Source: | NIH/NIAID |
| Role: | Co-I |
| Title: | Identifying mechanisms by which two critical global regulators coordinate metabolism and virulence in the group A Streptococcus |
| Funding Source: | NIH/NIAID |
| Role: | PI |
| ID: | R21AI168665 |
Selected Publications
Peer-Reviewed Articles
- Wallach, I, Bernard, D, Nguyen, K, Ho, G, Morrison, A, Stecula, A, Rosnik, A, O’Sullivan, AM, Davtyan, A, Samudio, B, Thomas, B, Worley, B, Butler, B, Laggner, C, Thayer, D, Moharreri, E, Friedland, G, Truong, H, van den Bedem, H, Ng, HL, Stafford, K, Sarangapani, K, Giesler, K, Ngo, L, Mysinger, M, Ahmed, M, Anthis, NJ, Henriksen, N, Gniewek, P, Eckert, S, de Oliveira, S, Suterwala, S, PrasadPrasad, SK, Shek, S, Contreras, S, Hare, S, Palazzo, T, O’Brien, TE, Van Grack, T, Williams, T, Chern, TR, Kenyon, V, Lee, AH, Cann, AB, Bergman, B, Anderson, BM, Cox, BD, Warrington, JM, Sorenson, JM, Goldenberg, JM, Young, MA, DeHaan, N, Pemberton, RP, Schroedl, S, Abramyan, TM, Gupta, T, Mysore, V, Presser, A, Ferrando, A, Andricopulo, AD, Ghosh, A, Ayachi, AG, Mushtaq, A, Shaqra, AM, Toh, AL, Smrcka, AV, Ciccia, A, de Oliveira, AS, Sverzhinsky, A, de Sousa, AM, Agulnik, AI, Kushnir, A, Freiberg, AN, Statsyuk, AV, Gingras, AR, Degterev, A, Tomilov, A, Vrielink, A, Garaeva, AA, Bryant-Friedrich, A, Caflisch, A, Patel, AK, Rangarajan, AV, Matheeussen, A, Battistoni, A, Caporali, A, Chini, A, Ilari, A, Mattevi, A, Foote, AT, Trabocchi, A, Stahl, A, Herr, AB, Berti, A, Freywald, A, Reidenbach, AG, Lam, A, Cuddihy, AR, White, A, Taglialatela, A, Ojha, AK, Cathcart, AM, Motyl, AA, Borowska, A, D’Antuono, A, Hirsch, AK, Porcelli, AM, Minakova, A, Montanaro, A, Müller, A, Fiorillo, A, Virtanen, A, O’Donoghue, AJ, Del Rio Flores, A, Garmendia, AE, Pineda-Lucena, A, Panganiban, AT, Samantha, A, Chatterjee, AK, Haas, AL, Paparella, AS, John, AL, Prince, A, ElSheikh, A, Apfel, AM, Colomba, A, O’Dea, A, Diallo, BN, Ribeiro, BM, Bailey-Elkin, BA, Edelman, BL, Liou, B, Perry, BG, Chua, BK, Kováts, B, Englinger, B, Balakrishnan, B, Gong, B, Agianian, B, Pressly, B, Salas, BP, Duggan, BM, Geisbrecht, BV, Dymock, BW, Morten, BC, Hammock, B, Mota, BF, Dickinson, BC, Fraser, C, Lempicki, C, Novina, CD, Torner, C, Ballatore, C, Bon, C, Chapman, CJ, Partch, C, Chaton, CT, Huang, C, Yang, CY, Kahler, CM, Karan, C, Keller, C, Dieck, CL, Huimei, C, Liu, C, Peltier, C, Mantri, CK, Kemet, C, Müller, CE, Weber, C, Zeina, CM, Muli, CS, Morisseau, C, Alkan, C, Reglero, C, Loy, CA, Wilson, CM, Myhr, C, Arrigoni, C, Paulino, C, Santiago, C, Luo, D, Tumes, DJ, Keedy, DA, Lawrence, DA, Chen, D, Manor, D, Trader, DJ, Hildeman, DA, Drewry, DH, Dowling, DJ, Hosfield, DJ, Smith, DM, Moreira, D, Siderovski, DP, Shum, D, Krist, DT, Riches, DW, Ferraris, DM, Anderson, DH, Coombe, DR, Welsbie, D, Hu, D, Ortiz, D, Alramadhani, D, Zhang, D, Chaudhuri, D, Slotboom, DJ, Ronning, DR, Lee, D, Dirksen, D, Shoue, DA, Zochodne, DW, Krishnamurthy, D, Duncan, D, Glubb, DM, Gelardi, EM, Hsiao, EC, Lynn, EG, Silva, EB, Aguilera, E, Lenci, E, Abraham, ET, Lama, E, Mameli, E, Leung, E, Christensen, EM, Mason, ER, Petretto, E, Trakhtenberg, EF, Rubin, EJ, Strauss, E, Thompson, EW, Cione, E, Lisabeth, EM, Fan, E, Kroon, EG, Jo, E, García-Cuesta, EM, Glukhov, E, Gavathiotis, E, Yu, F, Xiang, F, Leng, F, Wang, F, Ingoglia, F, Akker, Fd, Borriello, F, Vizeacoumar, FJ, Luh, F, Buckner, FS, Vizeacoumar, F, Bdira, FB, Svensson, F, Rodriguez, GM, Bognár, G, Lembo, G, Zhang, G, Dempsey, G, Eitzen, G, Mayer, G, Greene, GL, Garcia, GA, Lukacs, GL, Prikler, G, Parico, GG, Colotti, G, De Keulenaer, GW, Cortopassi, G, Roti, G, Girolimetti, G, Fiermonte, G, Gasparre, G, Leuzzi, G, Dahal, G, Michlewski, G, Conn, GL, Stuchbury, GD, Bowman, GR, Popowicz, GM, Veit, G, de Souza, GE, Akk, G, Caljon, G, Alvarez, G, Rucinski, G, Lee, G, Cildir, G, Li, H, Breton, HE, Jafar-Nejad, H, Zhou, H, Moore, HP, Tilford, H, Yuan, H, Shim, H, Wulff, H, Hoppe, H, Chaytow, H, Tam, HK, Van Remmen, H, Xu, H, Debonsi, HM, Lieberman, HB, Jung, H, Fan, HY, Feng, H, Zhou, H, Kim, HJ, Greig, IR, Caliandro, I, Corvo, I, Arozarena, I, Mungrue, IN, Verhamme, IM, Qureshi, IA, Lotsaris, I, Cakir, I, Perry, JP, Kwiatkowski, J, Boorman, J, Ferreira, J, Fries, J, Kratz, JM, Miner, J, Siqueira-Neto, JL, Granneman, JG, Ng, J, Shorter, J, Voss, JH, Gebauer, JM, Chuah, J, Mousa, JJ, Maynes, JT, Evans, JD, Dickhout, JG, MacKeigan, JP, Jossart, JN, Zhou, J, Lin, J, Xu, J, Wang, J, Zhu, J, Liao, J, Xu, J, Zhao, J, Lin, J, Lee, J, Reis, J, Stetefeld, J, Bruning, JB, Bruning, JB, Coles, JG, Tanner, JJ, Pascal, JM, So, J, Pederick, JL, Costoya, JA, Rayman, JB, Maciag, JJ, Nasburg, JA, Gruber, JJ, Finkelstein, JM, Watkins, J, Rodríguez-Frade, JM, Arias, JS, Lasarte, JJ, Oyarzabal, J, Milosavljevic, J, Cools, J, Lescar, J, Bogomolovas, J, Wang, J, Kee, JM, Kee, JM, Liao, J, Sistla, JC, Abrahão, JS, Sishtla, K, Francisco, KR, Hansen, KB, Molyneaux, KA, Cunningham, KA, Martin, KR, Gadar, K, Ojo, KK, Wong, KS, Wentworth, K, Lai, K, Lobb, KA, Hopkins, KM, Parang, K, Machaca, K, Pham, K, Ghilarducci, K, Sugamori, KS, McManus, K, Musta, K, Faller, KM, Nagamori, K, Mostert, KJ, Korotkov, KV, Liu, K, Smith, KS, Sarosiek, KA, Rohde, KH, Kim, KK, Lee, KH, Pusztai, L, Lehtiö, L, Haupt, LM, Cowen, LE, Byrne, LJ, Su, L, Wert-Lamas, L, Puchades-Carrasco, L, Chen, L, Malkas, LH, Zhuo, L, Hedstrom, L, Hedstrom, L, Walensky, LD, Antonelli, L, Iommarini, L, Whitesell, L, Randall, LM, Fathallah, MD, Nagai, MH, Kilkenny, ML, Ben-Johny, M, Lussier, MP, Windisch, MP, Lolicato, M, Lolli, ML, Vleminckx, M, Caroleo, MC, Macias, MJ, Valli, M, Barghash, MM, Mellado, M, Tye, MA, Wilson, MA, Hannink, M, Ashton, MR, Cerna, MC, Giorgis, M, Safo, MK, Maurice, MS, McDowell, MA, Pasquali, M, Mehedi, M, Serafim, MM, Soellner, MB, Alteen, MG, Champion, MM, Skorodinsky, M, O’Mara, ML, Bedi, M, Rizzi, M, Levin, M, Mowat, M, Jackson, M, Paige, M, Al-Yozbaki, M, Giardini, MA, Maksimainen, MM, De Luise, M, Hussain, MS, Christodoulides, M, Stec, N, Zelinskaya, N, Van Pelt, N, Merrill, NM, Singh, N, Kootstra, NA, Singh, N, Gandhi, NS, Chan, NL, Trinh, NM, Schneider, NO, Matovic, N, Horstmann, N, Longo, N, Bharambe, N, Rouzbeh, N, Mahmoodi, N, Gumede, NJ, Anastasio, NC, Khalaf, NB, Rabal, O, Kandror, O, Escaffre, O, Silvennoinen, O, Tastan, AÖ, Iglesias, P, Sobrado, P, Chuong, P, O’Connell, P, Martin-Malpartida, P, Mellor, P, Fish, PV, Moreira, PL, Zhou, P, Liu, P, Liu, P, Wu, P, Agogo-Mawuli, P, Jones, PL, Ngoi, P, Toogood, P, Ip, P, von Hundelshausen, P, Lee, PH, Rowswell-Turner, R, Balaña-Fouce, R, Rocha, RO, Guido, RV, Ferreira, RS, Agrawal, RK, Harijan, RK, Ramachandran, R, Verma, R, Singh, R, Tiwari, RK, Mazitschek, R, Koppisetti, RK, Dame, RT, Douville, RN, Austin, RC, Taylor, RE, Moore, RG, Ebright, RH, Angell, RM, Yan, R, Kejriwal, R, Batey, RA, Blelloch, R, Vandenberg, RJ, Hickey, RJ, Kelm, RJ, Lake, RJ, Bradley, RK, Blumenthal, RM, Solano, R, Gierse, RM, Viola, RE, McCarthy, RR, Reguera, RM, Uribe, RV, do Monte-Neto, RL, Gorgoglione, R, Cullinane, RT, Katyal, S, Hossain, S, Phadke, S, Shelburne, S, Geden, SE, Johannsen, S, Wazir, S, Legare, S, Landfear, SM, Radhakrishnan, SK, Ammendola, S, Dzhumaev, S, Seo, SY, Li, S, Zhou, S, Chu, S, Chauhan, S, Maruta, S, Ashkar, SR, Shyng, SL, Conticello, SG, Buroni, S, Garavaglia, S, White, SJ, Zhu, S, Tsimbalyuk, S, Chadni, SH, Byun, SY, Park, S, Xu, SQ, Banerjee, S, Zahler, S, Espinoza, S, Gustincich, S, Sainas, S, Celano, SL, Capuzzi, SJ, Waggoner, SN, Poirier, S, Olson, SH, Marx, SO, Van Doren, SR, Sarilla, S, Brady-Kalnay, SM, Dallman, S, Azeem, SM, Teramoto, T, Mehlman, T, Swart, T, Abaffy, T, Akopian, T, Haikarainen, T, Moreda, TL, Ikegami, T, Teixeira, TR, Jayasinghe, TD, Gillingwater, TH, Kampourakis, T, Richardson, TI, Herdendorf, TJ, Kotzé, TJ, O’Meara, TR, Corson, TW, Hermle, T, Ogunwa, TH, Lan, T, Su, T, Banjo, T, O’Mara, TA, Chou, T, Chou, TF, Baumann, U, Desai, UR, Pai, VP, Thai, VC, Tandon, V, Banerji, V, Robinson, VL, Gunasekharan, V, Namasivayam, V, Segers, VF, Maranda, V, Dolce, V, Maltarollo, VG, Scoffone, VC, Woods, VA, Ronchi, VP, Van Hung Le, V, Clayton, WB, Lowther, WT, Houry, WA, Li, W, Tang, W, Zhang, W, Van Voorhis, WC, Donaldson, WA, Hahn, WC, Kerr, WG, Gerwick, WH, Bradshaw, WJ, Foong, WE, Blanchet, X, Wu, X, Lu, X, Qi, X, Xu, X, Yu, X, Qin, X, Wang, X, Yuan, X, Zhang, X, Zhang, YJ, Hu, Y, Aldhamen, YA, Chen, Y, Li, Y, Sun, Y, Zhu, Y, Gupta, YK, Pérez-Pertejo, Y, Li, Y, Tang, Y, He, Y, Tse-Dinh, YC, Sidorova, YA, Yen, Y, Li, Y, Frangos, ZJ, Chung, Z, Su, Z, Wang, Z, Zhang, Z, Liu, Z, Inde, Z, Artía, Z, Heifets, A. AI is a viable alternative to high throughput screening. Scientific reports 14(1), 2024. e-Pub 2024. PMID: 38565852.
- Shelburne SA, Song X, Bremer J, Seo S, Rodriguez S, Selvaraj Anand S, Dinh AQ, Bhatti MM, Konovalova A, Arias CA, Kalia A, Shamoo Y, Shelburne SA. Comprehensive Assessment of Initial Adaptation of ESBL Positive ST131 Escherichia coli to Carbapenem Exposure. J Infect Dis, 2024. e-Pub 2024. PMID: 39602497.
- Gomez AA, Kjerfve C, Choi M, Liu W, Churion K, Thomas S, Rohde H, Shelburne S, Skare JT, Hook M, Arora S. Staphylococcus epidermidis ST2 strains associated with bloodstream infections contain a unique mobile genetic element encoding a plasmin inhibitor. mBio, 2024. e-Pub 2024. PMID: 39560391.
- Hayase E, Hayase T, Mukherjee A, Stinson SC, Jamal MA, Ortega MR, Sanchez CA, Ahmed SS, Karmouch JL, Chang CC, Flores II, McDaniel LK, Brown AN, El-Himri RK, Chapa VA, Tan L, Tran BQ, Xiao Y, Fan C, Pham D, Halsey TM, Jin Y, Tsai WB, Prasad R, Glover IK, Enkhbayar A, Mohammed A, Schmiester M, King KY, Britton RA, Reddy P, Wong MC, Ajami NJ, Wargo JA, Shelburne S, Okhuysen PC, Liu C, Fowler SW, Conner ME, Katsamakis Z, Smith N, Burgos da Silva M, Ponce DM, Peled JU, van den Brink MRM, Peterson CB, Rondon G, Molldrem JJ, Champlin RE, Shpall EJ, Lorenzi PL, Mehta RS, Martens EC, Alousi AM, Jenq RR. Bacteroides ovatus alleviates dysbiotic microbiota-induced graft-versus-host disease. Cell Host Microbe, 2024. e-Pub 2024. PMID: 39214085.
- El Haddad L, Angelidakis G, Zhai Y, Yaghi L, Arias CA, Shelburne SA, Jeong KC, Chemaly RF. Persistence of Daptomycin-Resistant and Vancomycin-Resistant Enterococci in Hospitalized Patients with Underlying Malignancies: A 7-Year Follow-Up Study. Microorganisms, 2024. e-Pub 2024. PMID: 39203518.
- Egge SL, Rizvi SA, Simar SR, Alcalde M, Martinez JRW, Hanson BM, Dinh AQ, Baptista RP, Tran TT, Shelburne SA, Munita JM, Arias CA, Hakki M, Miller WR. Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin. Antimicrob Agents Chemother, 2024. e-Pub 2024. PMID: 38995033.
- Shelburne SA, Vega LA, Mukherjee P, DebRoy S, Flores AR, Shelburne SA. Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells. Infect Immun, 2024. e-Pub 2024. PMID: 38888310.
- Odo, C, Vega, LA, Mukherjee, P, DebRoy, S, Flores, A, Shelburne, S. Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells. Infection and Immunity 92(7), 2024. e-Pub 2024. PMID: 38888310.
- Axell-House, DB, Ashley, PA, Egge, SL, Tran, TT, Pedroza, C, Zhang, M, Dinh, AQ, Simar, SR, Sahasrabhojane, P, Miller, WR, Shelburne, S, Hanson, B, Arias, CA. Clinical Features and Genomic Epidemiology of Bloodstream Infections due to Enterococcal Species Other Than Enterococcus faecalis or E. faecium in Patients With Cancer. Open Forum Infectious Diseases 11(6), 2024. e-Pub 2024. PMID: 38835498.
- Gerges, B, Rosenblatt, J, Truong, YL, Jiang, Y, Shelburne, S, Chaftari, AP, Hachem, RY, Raad, II. In vitro activity of cefepime/taniborbactam and comparator agents against Gram-negative bacterial bloodstream pathogens recovered from patients with cancer. JAC-Antimicrobial Resistance 6(2), 2024. e-Pub 2024. PMID: 38601790.
- Axell-House, DB, Simar, SR, Panesso, D, Rincon, S, Miller, WR, Khan, A, Pemberton, OA, Valdez, L, Nguyen, AH, Hood, KS, Rydell, K, DeTranaltes, AM, Jones, MN, Atterstrom, R, Reyes, J, Sahasrabhojane, P, Suleyman, G, Zervos, MJ, Shelburne, S, Singh, KV, Shamoo, Y, Hanson, B, Tran, TT, Arias, CA. LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium. Antimicrobial agents and chemotherapy 68(3), 2024. e-Pub 2024. PMID: 38289081.
- Kawai, A, Shropshire, WC, Suzuki, M, Borjan, J, Aitken, SL, Bachman, WC, Mcelheny, CL, Bhatti, MM, Shields, RK, Shelburne, S, Doi, Y. Structural insights into the molecular mechanism of high-level ceftazidime–avibactam resistance conferred by CMY-185. mBio 15(2), 2024. e-Pub 2024. PMID: 38179965.
- Anand, SS, Wu, CT, Bremer, J, Bhatti, MM, Treangen, TJ, Kalia, A, Shelburne, S, Shropshire, WC. Identification of a novel CG307 sub-clade in third-generation-cephalosporin-resistant Klebsiella pneumoniae causing invasive infections in the USA. Microbial genomics 10(2), 2024. e-Pub 2024. PMID: 38407244.
- Shropshire, W, Amiji, H, Bremer, J, Selvaraj-Anand, S, Strope, B, Sahasrabhojane, P, Gohel, M, Aitken, SL, Spitznogle, S, Zhan, X, Kim, J, Greenberg, DE, Shelburne, S. Genetic determinants underlying the progressive phenotype of β-lactam/β-lactamase inhibitor resistance in Escherichia coli. Microbiology spectrum 11(6):e0222123, 2023. e-Pub 2023. PMID: 37800937.
- Shropshire, WC, Endres, BT, Borjan, J, Aitken, SL, Bachman, WC, Mcelheny, CL, Wu, CT, Egge, SL, Khan, A, Miller, WR, Bhatti, MM, Saharasbhojane, P, Kawai, A, Shields, RK, Shelburne, S, Doi, Y. High-level ceftazidime/avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated β-lactamase CMY-185 variant. Journal of Antimicrobial Chemotherapy 78(10):2442-2450, 2023. e-Pub 2023. PMID: 37574665.
- Shropshire, WC, Strope, B, Anand, SS, Bremer, J, McDaneld, PM, Bhatti, MM, Flores, AR, Kalia, A, Shelburne, S. Temporal dynamics of genetically heterogeneous extended-spectrum cephalosporin-resistant Escherichia coli bloodstream infections. mSphere 8(4), 2023. e-Pub 2023. PMID: 37427953.
- DebRoy, S, Shropshire, W, Vega, LA, Tran, CN, Horstmann, N, Mukherjee, P, Selvaraj-Anand, S, Tran, TT, Bremer, J, Gohel, M, Arias, CA, Flores, A, Shelburne, S. Identification of distinct impacts of CovS inactivation on the transcriptome of acapsular group A streptococci. mSystems 8(4), 2023. e-Pub 2023. PMID: 37358280.
- Horstmann, N, Tran, CN, Flores, AR, Shelburne, S. Hyperphosphorylation of the Group A Streptococcal Control of Virulence Regulator Increases Promoter Occupancy Specifically at Virulence Factor-Encoding Genes. Journal of bacteriology 205(6), 2023. e-Pub 2023. PMID: 37289078.
- McMahon, S, Sahasrabhojane, P, Kim, J, Franklin, S, Chang, C, Jenq, RR, Hillhouse, A, Shelburne, S, Galloway-Pena, J. Contribution of the Oral and Gastrointestinal Microbiomes to Bloodstream Infections in Leukemia Patients. Microbiology spectrum 11(3), 2023. e-Pub 2023. PMID: 37022173.
- Gerges, B, Rolston, KV, Shelburne, S, Rosenblatt, J, Prince, RA, Raad, II. The in vitro activity of delafloxacin and comparator agents against bacterial pathogens isolated from patients with cancer. JAC-Antimicrobial Resistance 5(2), 2023. e-Pub 2023. PMID: 36994231.
- Rolston, KV, Gerges, B, Nesher, L, Shelburne, S, Prince, RA, Raad, II. In vitro activity of eravacycline and comparator agents against bacterial pathogens isolated from patients with cancer. JAC-Antimicrobial Resistance 5(2), 2023. e-Pub 2023. PMID: 36875177.
- Tran, TT, Cabrera, NL, Gonzales-Luna, AJ, Carlson, TJ, Alnezary, F, Miller, WR, Sakurai, A, Dinh, AQ, Rydell, K, Rios, R, Díaz, L, Hanson, BM, Munita, JM, Pedroza, C, Shelburne, S, Aitken, SL, Garey, K, Dillon, R, Puzniak, L, Arias, CA. Clinical characteristics, microbiology and outcomes of a cohort of patients treated with ceftolozane/tazobactam in acute care inpatient facilities, Houston, Texas, USA. JAC-Antimicrobial Resistance 5(1), 2023. e-Pub 2023. PMID: 36601551.
- Simar, SR, Tran, TT, Rydell, K, Panesso, D, Contreras, GA, Munita, JM, Cifuentes, RO, Abbo, LM, Sahasrabhojane, P, Dinh, AQ, Axell-House, DB, Savidge, TC, Shelburne, S, Hanson, BM, Arias, CA. Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida. Antimicrobial agents and chemotherapy 67(1), 2023. e-Pub 2023. PMID: 36541772.
- Schwabkey, Z, Wiesnoski, DH, Chang, C, Tsai, W, Pham, D, Ahmed, SS, Hayase, T, Ortega Turrubiates, MR, El-Himri, RK, Sanchez, CA, Hayase, E, Frenk Oquendo, AC, Miyama, T, Halsey, T, Heckel, BE, Brown, AN, Jin, Y, Raybaud, M, Prasad, R, Flores, I, McDaniel, L, Chapa, V, Lorenzi, PL, Warmoes, MO, Tan, L, Swennes, AG, Fowler, S, Conner, ME, McHugh, K, Graf, T, Jensen, VB, Peterson, CB, Do, K, Zhang, L, Shi, Y, Wang, Y, Galloway-Pena, J, Okhuysen, PC, Daniel-MacDougall, CR, Shono, Y, Burgos da Silva, M, Peled, JU, Van Den Brink, MR, Ajami, NJ, Wargo, J, Reddy, P, Valdivia, RH, Davey, L, Rondon, G, Srour, S, Mehta, RS, Alousi, AM, Shpall, E, Champlin, RE, Shelburne, S, Molldrem, JJ, Jamal, M, Karmouch, J, Jenq, RR. Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Science translational medicine 14(671), 2022. e-Pub 2022. PMID: 36383683.
- Tamma, PD, Komarow, L, Ge, L, Garcia-Diaz, J, Herc, ES, Doi, Y, Arias, CA, Albin, O, Saade, E, Miller, LG, Jacob, JT, Satlin, MJ, Krsak, M, Huskins, WC, Dhar, S, Shelburne, S, Hill, C, Baum, KR, Bhojani, M, Greenwood-Quaintance, KE, Schmidt-Malan, SM, Patel, R, Evans, S, Chambers, H, Fowler, VG, van Duin, D. Clinical Impact of Ceftriaxone Resistance in Escherichia coli Bloodstream Infections. Open Forum Infectious Diseases 9(11), 2022. e-Pub 2022. PMID: 36381622.
- Hayase, E, Hayase, T, Jamal, M, Miyama, T, Chang, C, Ortega, MR, Ahmed, SS, Karmouch, J, Sanchez, CA, Brown, AN, El-Himri, RK, Flores, I, McDaniel, L, Pham, D, Halsey, T, Frenk, AC, Chapa, V, Heckel, BE, Jin, Y, Tsai, W, Prasad, R, Tan, L, Veillon, L, Ajami, NJ, Wargo, J, Galloway-Pena, J, Shelburne, S, Chemaly, RF, Davey, L, Glowacki, RW, Liu, C, Rondon, G, Alousi, AM, Molldrem, JJ, Champlin, RE, Shpall, E, Valdivia, RH, Martens, EC, Lorenzi, PL, Jenq, RR. Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease. Cell 185(20):3705-3719.e14, 2022. e-Pub 2022. PMID: 36179667.
- Shropshire, WC, Konovalova, A, McDaneld, PM, Gohel, M, Strope, B, Sahasrabhojane, P, Tran, CN, Greenberg, DE, Kim, J, Zhan, X, Aitken, SL, Bhatti, MM, Savidge, TC, Treangen, TJ, Hanson, BM, Arias, CA, Shelburne, S. Systematic Analysis of Mobile Genetic Elements Mediating b-Lactamase Gene Amplification in Noncarbapenemase- Producing Carbapenem-Resistant Enterobacterales Bloodstream Infections. mSystems 7(5), 2022. e-Pub 2022. PMID: 36036505.
- Vega, LA, Sanson, M, Cubria, MB, Regmi, S, Shah, BJ, Shelburne, S, Flores, AR. The Integrative Conjugative Element ICESpyM92 Contributes to Pathogenicity of Emergent Antimicrobial-Resistant emm92 Group A Streptococcus. Infection and Immunity 90(8), 2022. e-Pub 2022. PMID: 35913172.
- Bhalodi, AA, Macvane, SH, Ford, B, Ince, D, Kinn, PM, Percival, KM, Bremmer, DN, Carr, DR, Walsh, TL, Bhatti, MM, Shelburne, S, Humphries, RM, Wolfe, K, Rosenbaum, ER, Dare, RK, Kolev, J, Madhusudhan, M, Ben-Aderet, MA, Morgan, MA. Real-World Impact of the Accelerate PhenoTest BC Kit on Patients with Bloodstream Infections in the Improving Outcomes and Antimicrobial Stewardship Study. Clinical Infectious Diseases 75(2):269-277, 2022. e-Pub 2022. PMID: 34718456.
- Rolston, KV, Gerges, B, Reitzel, R, Shelburne, S, Aitken, SL, Raad, II, Prince, RA. In vitro activity of imipenem/releactam and comparator agents against clinical bacterial isolates from patients with cancer. Journal of Global Antimicrobial Resistance 29:1-6, 2022. e-Pub 2022. PMID: 35121163.
- Shropshire, WC, Dinh, AQ, Earley, M, Komarow, L, Panesso, D, Rydell, K, Gómez-Villegas, SI, Miao, H, Hill, C, Chen, L, Patel, R, Fries, BC, Abbo, LM, Cober, E, Revolinski, S, Luterbach, CL, Chambers, H, Fowler, VG, Bonomo, RA, Shelburne, S, Kreiswirth, BN, van Duin, D, Hanson, BM, Arias, CA. Accessory Genomes Drive Independent Spread of Carbapenem- Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX. mBio 13(2), 2022. e-Pub 2022. PMID: 35357213.
- Franklin, S, Aitken, SL, Shi, Y, Sahasrabhojane, P, Robinson, S, Peterson, CB, Daver, N, Ajami, NJ, Kontoyiannis, DP, Shelburne, S, Galloway-Pena, J. Oral and Stool Microbiome Coalescence and Its Association With Antibiotic Exposure in Acute Leukemia Patients. Frontiers in Cellular and Infection Microbiology 12, 2022. e-Pub 2022. PMID: 35433514.
- Contreras, GA, Munita, JM, Simar, SR, Luterbach, CL, Dinh, AQ, Rydell, K, Sahasrabhojane, P, Rios, R, Díaz, L, Reyes, K, Zervos, MJ, Misikir, HM, Petitto, GS, Liu, C, Doi, Y, Abbo, LM, Shimose, LA, Seifert, H, Gudiol, C, Barberis, F, Pedroza, C, Aitken, SL, Shelburne, S, van Duin, D, Tran, TT, Hanson, BM, Arias, CA. Contemporary Clinical and Molecular Epidemiology of Vancomycin-Resistant Enterococcal Bacteremia. Open Forum Infectious Diseases 9(3), 2022. e-Pub 2022. PMID: 35155713.
- Horstmann, N, Myers, KS, Tran, CN, Flores, AR, Shelburne, S. CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A Streptococcus. PLoS pathogens 18(2), 2022. e-Pub 2022. PMID: 35180278.
- Sanson, M, Vega, LA, Shah, BJ, Regmi, S, Belen Cubria, M, Horstmann, N, Shelburne, S, Flores, AR. The LiaFSR Transcriptome Reveals an Interconnected Regulatory Network in Group A Streptococcus. Infection and Immunity 89(11), 2021. e-Pub 2021. PMID: 34370508.
- DebRoy, S, Shropshire, WC, Tran, CN, Hao, H, Gohel, M, Galloway-Pena, J, Hanson, BM, Flores, AR, Shelburne, S. Characterization of the Type I Restriction Modification System Broadly Conserved among Group A Streptococci. mSphere 6(6), 2021. e-Pub 2021. PMID: 34787444.
- DebRoy, S, Sanson, M, Shah, BJ, Regmi, S, Vega, LA, Odo, C, Sahasrabhojane, P, McGeer, A, Tyrrell, GJ, Fittipaldi, N, Shelburne, S, Flores, AR. Population genomics of emm4 group a streptococcus reveals progressive replacement with a hypervirulent clone in north america. mSystems 6(4), 2021. e-Pub 2021. PMID: 34374563.
- DebRoy, S, Aliaga-Tobar, V, Galvez, G, Arora, S, Liang, X, Horstmann, N, Maracaja-Coutinho, V, Latorre, M, Hook, M, Flores, AR, Shelburne, S. Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus. Molecular Microbiology 115(6):1207-1228, 2021. e-Pub 2021. PMID: 33325565.
- Olvera, AV, Carter, HE, Rajan, A, Carlin, LG, Yu, X, Zeng, XL, Shelburne, S, Bhatti, MM, Blutt, SE, Shroyer, NF, Jenq, RR, Estes, MK, Maresso, AW, Okhuysen, PC. Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients. Clinical Infectious Diseases 72(10):E620-E629, 2021. e-Pub 2021. PMID: 32930708.
- Aitken, SL, Sahasrabhojane, P, Kontoyiannis, DP, Savidge, TC, Arias, CA, Ajami, NJ, Shelburne, S, Galloway-Pena, J. Alterations of the Oral Microbiome and Cumulative Carbapenem Exposure Are Associated With Stenotrophomonas maltophilia Infection in Patients With Acute Myeloid Leukemia Receiving Chemotherapy. Clinical Infectious Diseases 72(9):1507-1513, 2021. e-Pub 2021. PMID: 32544947.
- Shropshire, WC, Aitken, SL, Pifer, R, Kim, J, Bhatti, MM, Li, X, Kalia, A, Galloway-Pena, J, Sahasrabhojane, P, Arias, CA, Greenberg, DE, Hanson, BM, Shelburne, S. IS26-mediated amplification of blaOXA-1and blaCTX-M-15with concurrent outer membrane porin disruption associated with de novo carbapenem resistance in a recurrent bacteraemia cohort. Journal of Antimicrobial Chemotherapy 76(2):385-395, 2021. e-Pub 2021. PMID: 33164081.
- Satlin, MJ, Weissman, SJ, Carpenter, P, Seo, SK, Shelburne, S. American Society of Transplantation and Cellular Therapy Series, 1. Transplantation and Cellular Therapy 27(2):108-114, 2021. e-Pub 2021. PMID: 33781545.
Review Articles
- Mojica, MF, Humphries, RM, Lipuma, JJ, Mathers, AJ, Rao, GG, Shelburne, S, Fouts, DE, van Duin, D, Bonomo, RA. Clinical challenges treating Stenotrophomonas maltophilia infections. JAC-Antimicrobial Resistance 4(3), 2022. e-Pub 2022. PMID: 35529051.
- Shah, S, Shelburne, S. Skin and Soft Tissue Infections in Non–Human Immunodeficiency Virus Immunocompromised Hosts. Infectious Disease Clinics of North America 35(1):199-217, 2021. e-Pub 2021. PMID: 33303336.
Other Articles
- Torres, HA, Mustafayev, K, Nastoupil, L, Shelburne, S Severe reactivation of seronegative occult hepatitis B after chemotherapy for lymphoma. The Lancet 403(10434):1372-1373, 2024. PMID: 38582568.
Abstracts
- Kawai A, Shropshire WC, Suzuki M, Borjan J, Aitken SL, Bachman WC, McElheny CL, Bhatti MM, Shields RK, Shelburne SA, Doi Y. Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185. mBio, 2024. e-Pub 2024. PMID: 38179965.
- Koenig AN, Lui C, Zhang J, Hu PC, Thompson EJ, Shelburne SA, Kalia A. Population Genomics of the Streptococcus dysgalactiae subspecies equisimilis FCT-locus Reveals a Diverse Array of FCT Architectures & Shared Gene Contact with Group A Streptoccus. ASM Microbe 2019, 2019. e-Pub 2019.
- S L Aitken SL, Bhatti M, Sahasrabhojane P, Galloway-Pena J, Li X, Tverdek FP, Reeves C, McDaneld P, Greenberg D, Shelburne S. Epidemiology and Mechanisms of Carbapenem Resistance in Recurrent Extended-Spectrum β-lactamase- Producing Enterobacteriaceae Bacteremia. Infectious Diseases of America Annual Meeting, 2018. e-Pub 2018.
- Contreras G, Munita JM, Reyes KC, Sahasrabhojane P, Misikir H, Garza H, Zervos MJ, Aitken SL, Shelburne SA, Arias C. VENOUS 1: A Prospective Multicenter Cohort Study of Enterococcal Bacteremia. Infectious Diseases of America Annual Meeting, 2018. e-Pub 2018.
- Wilson Dib R, Li X, Shelburne SA, Chaftari AM, Hachem RY, Reitzel R, Vargas-Cruz N, Holland TL, Fowler Jr VG, Raad I. Whole Genome Sequencing Analysis of a Large Cohort of Staphylococcus epidermidis Blood Culture Positive Isolates from a Multicenter Clinical Trial. Infectious Diseases of America Annual Meeting, 2018. e-Pub 2018.
- Flores AR, Galloway-Pena J, Shelburne III SA. High prevalence of antimicrobial resistance genes uncovered through whole genome sequencing of sequence Type 1 Group B Streptococcus. ASM Microbe 2018, 2018. e-Pub 2018.
- Horstmann N, Tran C, DebRoy S, Brumlow C, Yao H, Makthal N, Kumaraswami M, Shelburne S. CovS phosphatase activity is pivotal for Streptococcus pyogenes virulence. Research Retreat, Division of Internal Medicine, MD Anderson Cancer Center, 2018. e-Pub 2018.
- Galloway-Peña J, DebRoy S, Brumlow C, Li X, Horstmann N, Yao H, Chen K, Bhatti M, Kalia A, Shelburne S. Hypervirulent Group A Streptococcus Emergence in an Acaspular Background is Associated with Marked Remodeling of the Bacterial Cell Surface. Research Retreat, Division of Internal Medicine, MD Anderson Cancer Center, 2018. e-Pub 2018.
- Contreras G, Diaz L, Rios R, Reyes KC, Kamboj M, Lewis J, Rincon S, Reyes J, Carvajal LP, Panesso D, Sifri CD, Zervos M, Pamer E, Tran TT, Shelburne S, Munita J, Arias C. A Whole Genome Sequencing (WGS) Approach to Predict Daptomycin (DAP) Susceptibility of Enterococcus faecium. Infectious Diseases of America Annual Meeting, 2017. e-Pub 2017.
- Galloway-Pena JR, Shah DP, Sahasrabhojane P, Brunlow CE, Carlin LG, Peterson BC, Alousi AM, Shpall EJ, Chemaly RF, Kontoyiannis DP, SHELBURNE SA, Okhuysen PC. Longitudinal fecal microbiome and metabolite analyses identifies potential biomarkers for prediction of graft vs. host disease in hematopoietic stem cell transplant recipients. American Society for Microbiology Microbe, 2017. e-Pub 2017.
- Muñoz N, Minhaj A, Golardi A, Jasso JA, Ensor J, Dixon K, Feldman A, Appleton-Figueira T, Galloway-Peña J, Hill L, SHELBURNE SA, Tam AL. Oral and gut microbiome temporal variability in hospitalized cancer patients. Keystone Symposium on Microbiome Health and Disease, 2017. e-Pub 2017.
- Wilson Dib R, Numan Y, Li X, Kalia A, Raad I, SHELBURNE SA. Invasive Staphylococcus epidermidis isolates are highly clonal and distinct from commensal strains: time for a new paradigm in infection control?. Infectious Diseases Society of America Annual Meeting, 2017. e-Pub 2017.
- Aitken S, Jandhyala D, Mulanovich VE Marx K, Tverdek F, Chemaly R, Rolston KV, SHELBURNE SA. Patterns of linezolid and daptomycin use in leukemia patients with neutropenic fever presenting to the emergency center. Infectious Diseases Society of America Annual Meeting, 2017. e-Pub 2017.
- Munita J, Sahasrabhojane P, Petitto G, Araos R, Wanger A, Aitken S, SHELBURNE SA Arias CA. Prospective study of enterococcal bacteremia in cancer vs. non-cancer populations: one disease, two tales. Infectious Diseases Society of America Annual Meeting, 2017. e-Pub 2017.
- Li X, Numan Y, Kalia A, SHELBURNE SA. Whole genome sequence based identification of a ST-5 sub-cluster of linezolid resistant Staphylococcus epidermidis causing invasive disease in cancer patients. American Society for Microbiology Microbe, 2017. e-Pub 2017.
- Galloway-Peña J, Shah D, Sahasrabohjane P, Brumlow C, Carlin L, Peterson L, Alousi A, Shpall E, Chemaly R, Kontoyiannis D, SHELBURNE SA, Okhuysen P. Irreversible electroporation combined with parenteral antibiotics enhances treatment of osteomyelitis caused by Staphylococcus aureus in a rabbit model. Radiological Society of North America (RSNA) Conference, 2017. e-Pub 2017.
- Jandhyala D, Mulanovich VE, Aitken S, Tverdek F, Chemaly R, Marx K, Rolston KV, SHELBURNE SA. A contemporary analysis of neutropenic fever in leukemia patients presenting to the emergency center – importance of pneumonia. Infectious Diseases Society of America Annual Meeting, 2017. e-Pub 2017.
- Rolston KV, Reitzel R, Vargas-Cruz S, SHELBURNE SA, Raad II, Prince RA. In vitro activity of tedizolid and comparator agents against clinical isolates from cancer patients. American Society for Microbiology Microbe, 2017. e-Pub 2017.
- Mishra NN, Seepersaud R, Tran TT, SHELBURNE SA, Miro JM, Rybak MJ, Arias CA, Sullamm PM, Bayer AS. Phenotypic and genotypic characteristics of in vitro selected high level daptomycin resistant (DAP-R) strains of clinically derived Streptococcus mitis. American Society for Microbiology Microbe, 2017. e-Pub 2017.
- Jandhyala D, Mulanovich VE, Aitken S, Tverdek F, Marx K, Chemaly R, Rolston KV, SHELBURNE SA. Prophylactic antibiotic therapy and bloodstream infections in leukemia patients presenting to the emergency center. Infectious Diseases Society of America Annual Meeting, 2017. e-Pub 2017.
- Galloway-Peña J, Smith D, Wadsworth WD, Ajami N, Guindani M, Petrosino J, SHELBURNE SA. The effects of antibiotic exposure on microbiome diversity, microbiome stability, and clinical outcomes during induction remission chemotherapy in acute myeloid leukemia patients. 26th Annual Keck Research Conference Progress and Challenges in Combating Antimicrobial Resistance, 2017. e-Pub 2017.
- Argiento R, Guindani M, Vannucci M, Wadsworth D, Galloway-Pena J, Shelburne S. A Bayesian Dirichlet-Multinomial Regression Model for the Analysis of Taxonomic Abundances in Microbiome data. CMStatistics 2016, 2016. e-Pub 2016.
- Muñoz NM, Minhaj AA, Galloway-Peña JR, Melancon MP, Shelburne SA, Tam AL. Irreversible electroporation for control of osteomyelitis caused by Staphylococcus aureus. SIR 2016, 2016. e-Pub 2016.
- Folan SA, Tverdek F, Tarrand JF, SHELBURNE SA, Raad I, Mulanovich VE, Marx KR, Aitken SL. Empiric linezolid use is associated with adverse short term outcomes in patients with linezolid-resistant Staphylococcus epidermidis bloodstream infections. Infectious Diseases Society of America Annual Meeting, 2016. e-Pub 2016.
- DiPippo AJ, Tverdek FP, Tarrand JJ, Munita JM, Tran TT, Arias CA, SHELBURNE SA, Aitken SL. Daptomycin non-susceptible Enterococcus faecium in leukemia patients: Role of prior daptomycin exposure. Infectious Diseases Society of America Annual Meeting, 2016. e-Pub 2016.
- Galloway-Pena, J, Shelburne, SA. Prospective Cohort Study of the Oral and Fecal Microbiome During Induction Remission Chemotherapy in Acute Myelogenous Leukemia. ICAAC/ICC, San Diego, CA, 2015. e-Pub 2015.
- Galloway-Pena, J, Shelburne, SA. Tri-genomic Approach to Investigate Host-Pathogen-Commensal Interaction in a Leukemic Patient with Mucormycosis. ICAAC/ICC 2015-San Diego, CA, 2015. e-Pub 2015.
- PhD JG, PhD DS, Sahasrabhojane P, PhD NA, PhD AF, PhD JP, MD ScD DK, Samuel Shelburne III MD, PhD. Temporal Instability of the Oral and Stool Microbiomes During Induction Chemotherapy for Acute Myeloid Leukemia. Cell-CHIN-Symposium: Human Immunity and the Microbiome in health and Disease 2015, 2015. e-Pub 2015.
- Galloway-Pena, J, Shelburne, SA. First Steps in Analyzing Vaginal Microbiome Data: A Clinically Applied Analysis Discussion. Joint Statistical Meeting 2016, 2015. e-Pub 2015.
- Galloway-Pena, J, Shelburne, SA. Application of a Tri- Genomic Approach to Study Host-Pathogen-Commensal Interaction and Infectious Disease Susceptibility. 1st Place in Clinical Research at the Division of Internal Medicine Research Retreat, 2015. e-Pub 2015.
- Aitken SL, Tarrand JJ, Deshpande LM, Tverdek FP, SHELBURNE SA, Chemaly RF, Prince RA, Rolston KV, Jones RN, Castanheira M. Dissemination of NDM-1 among diverse Enterobacteriaceae in Houston is not related to plasmid-mediated spread. International Congress of Antimicrobial Agents and Chemotherapy, 2015. e-Pub 2015.
- Shukla B, SHELBURNE SA, Reyes K, Lewis J, Rincon S, Panesso D, Adachi J, Sifri CD, MD, Zervos M, Munita J, Hasbun R, Arias C. Influence of MIC in clinical outcomes of Enterococcus faecium bacteremia treated with daptomycin: is it time to change the breakpoint?. Infectious Diseases Society of America Annual Meeting, 2015. e-Pub 2015.
- Malik F, Okhuysen P, Alousi A, Shpall E, SHELBURNE SA, Petrosino J, Rezvani K, Ajami NJ, Ghosh N, Carlin L, Chemaly R. Fecal indole correlates with loss of microbiome diversity in hematopoietic stem cell transplant (HSCT) recipients with and without intestinal graft versus host disease (iGVHD). Infectious Diseases Society of America Annual Meeting, 2015. e-Pub 2015.
- Horstmann N, Saldana M, Sahasrabhojane P, Yao H, Su X, Thompson E, Koller A, Shelburne SA. Regulation of dual-site phosphorylation of response regulator CovR and its impact on group A streptococcus global gene expression and virulence. 8th International Conference on Gram-Positive Microorganisms, Montecatini Terme, 2015. e-Pub 2015.
- Teatero S, Athey TB, Van Caeseele P, Horsman G, Alexander DC, Melano RG, Li A, Flores AR, SHELBURNE SA, McGeer A, Demczuk W, Martin I, Fittipaldi N. Emergence of serotype IV group B Streptococcus adult invasive disease in Manitoba and Saskatchewan, Canada, is driven by clonal sequence type 459 strains. American Society for Microbiology Annual Meeting, 2015. e-Pub 2015.
- Galloway-Pena, J, Shelburne, SA. Monitoring The Microbiome in Leukemia Patients Could Reduce Infections During Chemotherapy. Podcast and live stream internet interview, ASM Live at ICAAC/ICC, 2015. e-Pub 2015.
- Galloway-Peña J, Sahasrabhojane P, Margarit I, Rosini R, Grandi G, McGeer A, Teatero S, Fittipaldi N, Baker C, Shelburne SA, R Flores AA. Small Genetic Changes Drive Phenotypic Diversity Among Sequence Type 1 Group B Streptococcus, An Emerging Cause of Invasive Disease in Adult Humans. IDWeek (IDSA) 2014 in the Immune Response to Microbial Infection Session, 2014. e-Pub 2014.
- Galloway-Pena, J, Shelburne, SA. Single Nucleotide Polymorphisms Drive Phenotypic Diversity among Sequence Type 1 Group B Streptococcus, An Emerging Cause Of Invasive Disease In Adult Humans. 2nd Place in Basic Research at the Division of Internal Medicine Research Retreat, 2014. e-Pub 2014.
- Galloway-Pena, J, Shelburne, SA. Elucidation of the Microbiome Landscape of Acute Myelogenous Leukemia Patients Undergoing Induction Remission Chemotherapy. 1st Place in Clinical Research at the Division of Internal Medicine Research Retreat, 2014. e-Pub 2014.
- Galloway-Pena, J, Shelburne, SA. Analysis of Fluoroquinolone Resistance In Viridans Group Streptococci Causing Invasive Disease in Cancer Patients. Spring 2014 American Society of Microbiology (ASM) Texas Branch Meeting, 2014. e-Pub 2014.
- Galloway-Pena, J, Shelburne, SA. Elucidation of the Changes in the Microbiome and its Role in Septicemia and Neutropenic Fever in Acute Myelogenous Leukemia Patients Undergoing Induction Remission Chemotherapy. Invited oral presentation at the Molecular Basis of Infectious Diseases Conference, 2014. e-Pub 2014.
- Sahasrabhojane P, MS, Saldaña M, Galloway-Peña J, PhD, Shelburne S, MD, PhD. Novel insights into the emergence of a hypervirulent group A Streptococcus strain revealed by whole genome sequencing of multiple clinical isolates from the same patient. Symposia on Cancer Research 2013, “Genomic Medicine”,, 2013. e-Pub 2013.
- Flores AR, Sahasrabhojane P, Saldaña M, Galloway-Peña J, Olsen RJ, Musser JM, A Shelburne AS. Documentation of an Invasive Phenotype of Group A Streptococcus Arising During Human Infection Using Whole Genome Sequencing of Multiple Clinical Isolates From the Same Patient. Symposia on Cancer Research 2013: “Genomic Medicine”, 2013. e-Pub 2013.
- Shelburne SA, Candice W, Catherine M. Improving the Treatment of Staphylococcus aureus bacteremia. University of Texas Clinical Safety and Effectiveness conference in San Antonio, 2013. e-Pub 2013.
- SHELBURNE SA, Sahasrabhojane P, Tarrand JJ, Rolston KV. Development and validation of a clinical model to predict the presence of β-lactam resistance in viridans group streptococci causing bacteremia in neutropenic cancer Patients. MD Anderson Internal Medicine Research Retreat, 2013. e-Pub 2013.
- Shelburne S, Sahasrobhojane P, Tarrand J, Yao H. Identification and Characterization of Streptococcus mitis Strains Causing Severe Clinical Disease in Cancer Patients. MD Anderson Internal Medicine Research Retreat, 2013. e-Pub 2013.
- Shelburne S, Sahasrabhojane P, Tarrand J, Rolston K. Development and Validation of a Clinical Model to Predict the Presence of β-lactam Resistance in Viridans Group Streptococci Causing Bacteremia in Neutropenic Cancer Patients. MD Anderson Internal Medicine Research Retreat, 2013. e-Pub 2013.
- Torres HA, Rallapalli V, Saxena A, Granwehr B, Viola G, Ariza E, Marfatia R, Jiang Y, Adachi J, Chemaly R, SHELBURNE SA, Mulanovich V. Efficacy and safety of antiretovirals in HIV-infected patients with cancer. International Congress of Antimicrobial Agents and Chemotherapy, 2013. e-Pub 2013.
- Shelburne SA, Sahasrobhojane P, Saldana M. Identification and Genome-Level Characterization of Highly Virulent Viridians Group Streptococci Causing Invasive Disease in Patients with Malignancy. Infectious Diseases Society of America 2012. San Diego CA, 2012. e-Pub 2012.
- Shelburne SA, Tarrand J, Rolston K. Invasive Streptococcal Infections at a United States Cancer Center 2000-2011. Infectious Diseases Society of America 2012. San Diego CA, 2012. e-Pub 2012.
- Shelburne SA, Tarrand J. Viridans Group Streptococcal Bloodstream and Alpha Streptococcal Shock Syndrome Rates are Increasing in the Era of Antimicrobial Prophylaxis. MD Anderson Internal Medicine Research Retreat, 2012. e-Pub 2012.
- Shelburne SA, Tarrand J, Rolston K. Epidemiology, Treatment, and Outcomes of Viridans Group Streptococcal Bloodstream Infections in the Era of High Rates of Antimicrobial Prophylaxis and Empiric Vancomycin Use. Infectious Diseases Society of America 2012, San Diego CA, 2012. e-Pub 2012.
- Horstmann N, Sahasrabhojane P, Suber B, Kumaraswami M, Olsen RJ, Flores A, Musser JM, Brennan RG, Shelburne SA. Distinct single amino Acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis. International Congress of Antimicrobial Agents and Chemotherapy, Chicago, IL, 2011. e-Pub 2011.
- Lin E, Bhusal Y, Horwitz D, SHELBURNE SA, Trautner B. Enterococcal bacteriuria is often overtreated and rarely leads to infectious complications. Infectious Diseases Society of America Annual Meeting, 2011. e-Pub 2011.
- Shelburne SA, Carroll RK, Olsen RJ, Suber B, Sahasrabhojane P, Kumaraswami M, Beres SB, Shea PR, Flores AR, Musser JM. Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice. Program and abstracts of the American Society for Clinical Investigation/Association of American Physicians Joint Meeting, Chicago, IL and The MDACC Department of Internal Medicine Research Retreat, 2011. e-Pub 2011.
- Lin E, Horowitz D, Bhusal Y, Roig I, Shelburne SA, Trautner B. Asymptomatic enterococcal bacteruria has a low rate of infectious complications. Program and abstracts of the 48th Annual IDSA Meeting, Vancouver, BC, 2010. e-Pub 2010.
- Lin E, Horwitz D, Bhusal Y, Roig I, SHELBURNE SA, Trautner B. Enterococcal Bacteriuria Is Often Managed Inappropriately. Infectious Diseases Society of America Annual Meeting, 2010. e-Pub 2010.
- Shelburne SA, Suber B, Sahasrobhojane P. A MalR-regulated protein that binds linear glucose polymers is critical to streptococcal oropharyngeal adherence. MDACC Department of Internal Medicine Research Retreat, 2010. e-Pub 2010.
- SHELBURNE SA, Horstmann N, Brennan RG, and Musser JM. Interaction between transcriptional regulatory proteins contributes to the pathogenesis of invasive group A streptococcal disease. Program and abstracts of the American Society for Clinical Investigation/Association of American Physicians Joint Meeting, 2009. e-Pub 2009.
- Shelburne SA, Olsen RJ, Brennan RG, Musser JM. Identification of the molecular mechanism by which CcpA contributes to the pathogenesis of streptococcal infection. Program and abstracts of the American Society for Clinical Investigation/Association of American Physicians Joint Meeting, Chicago, IL, 2009. e-Pub 2009.
- Shelburne SA, Keith D, Horstaman N, Sumby P, Davenport M, Graviss EA, Brennan RG, Musser JM. A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. Program and abstracts of the American Society for Clinical Investigation/Association of American Physicians Joint Meeting, Chicago, IL, 2008. e-Pub 2008.
- Shelburne SA, Keith D, Davenport M, Musser JM. Role of extracellular polysaccharide degrading enzymes in group A streptococcal pathogenesis. Program and abstracts of the 2008 IDSA/ICAAC Joint Meeting, Washington, DC. (poster presentation), 2008. e-Pub 2008.
- Shelburne SA, Keith DB, Sumby P, Fang H, Sitkiewicz I, Austin CM, Graviss EA, Chow DC, Musser JM. Group A Streptococcus uses human salivary α-amylase to catabolize glucans. Program and abstracts of the American Society for Clinical Investigation/Association of American Physicians Joint Meeting, Chicago, IL, 2007. e-Pub 2007.
- Shelburne SA, Sumby P, Sitkiewicz I, Okorafor N, Granville G, Patel P, Voyich J, Hull R, DeLeo FR, Musser JM. Maltodextrin utilization plays a key role in the ability of group A Streptococcus to colonize the oropharynx. Program and abstracts of the 44th Annual IDSA Meeting, Toronto, ON, (oral presentation), 2006. e-Pub 2006.
- Shelburne SA, Granville C, Tokuyama M, Sitkiewicz I, Patel P, Musser JM. Growth characteristics and virulence factor production by group A Streptococcus during cultivation in human saliva. Program and abstracts of the 43rd Annual IDSA Meeting, San Francisco, CA,, 2005. e-Pub 2005.
- Daver NG, Shelburne SA, Atmar R, Giordano T, Reitman C, Jr WA. IV to oral step-down therapy comparable to parenteral therapy for staphylococcal osteomyelitis. Program and abstracts of the 43rd Annual IDSA Meeting, San Francisco, CA,, 2005. e-Pub 2005.
- Sutarwala A, Rueda A, Shelburne SA. Bactericidal activity of orally available agents against methicillin-resistant Staphylococcus aureus. Programs and abstracts of the 43rd Annual IDSA meeting, San Francisco, CA,, 2005. e-Pub 2005.
- Shelburne SA, Darcourt J, White AC, Greenberg S, Hamill RJ, Atmar R, Visnegarwala F. Incidence and risk factors for immune reconstitution inflammatory syndrome (IRIS) among patients with Cryptococcus neoformans infection. Program and abstracts of the 11th Annual Conference on Retroviruses and Opportunistic Infections, San Francisco, CA,, 2004. e-Pub 2004.
- SHELBURNE SA, Giordano TP, Visnegarwala F, Graviss EA, Darcourt J, Hamill RJ, White AC. Prevalence of immune reconstitution inflammatory syndrome (IRIS) during highly active antiretroviral therapy (HAART) in HIV-infected patients with Mycobacterium tuberculosis (MTB), Mycobacterium avium complex (MAC), or Cryptococcus neoformans infection. Infectious Diseases Society of America Annual Meeting, 2003. e-Pub 2003.
- Shelburne SA, Darcourt J, Visnegarwala F, Giordano T, Graviss E, Hamill RJ. Incidence and risk factors for immune reconstitution inflammatory syndrome in HIV-infected patients infected with Mycobacterium tuberculosis, Mycobacterium avium complex, or Cryptococcus neoformans who are treated with highly active antiretroviral therapy. Program and abstracts of the 41st Annual IDSA Meeting, San Diego, CA,, 2003. e-Pub 2003.
- Shelburne SA, Hamill RJ, Rodriguez-Barradas MC, Greenberg SB, Gathe JC, Trautner B, Visnegarwala F, Atmar RL. Immune reconstitution inflammatory syndrome (IRIS): emergence of unique syndrome during highly active antiretroviral therapy (HAART). 39th Annual IDSA Meeting, San Francisco, CA,, 2001. e-Pub 2001.
Patient Reviews
CV information above last modified March 06, 2026