Sanam Loghavi, M.D.

Peer-Reviewed Articles

1. Loghavi S, Curry JL, Garcia-Manero G, Patel KP, Xu J, Khoury JD, Torres-Cabala CA, Nagarajan P, Aung PP, Gibson BR, Goodwin BP, Kelly BC, Korivi BR, Medeiros LJ, Prieto VG, Kantarjian HM, Bueso-Ramos CE, Tetzlaff MT. Chronic myelomonocytic leukemia masquerading as cutaneous indeterminate dendritic cell tumor: expanding the spectrum of skin lesions in chronic myelomonocytic leukemia. J Cutan Pathol 44(12):1075-1079, 2017. e-Pub 2017. PMID: 28885734.
2. Agbay RLMC, Medeiros LJ, Khoury JD, Salem A, Bueso-Ramos CE, Loghavi S. Characteristics and Clinical Implications of Reactive Germinal Centers in the Bone Marrow. Hum Pathol 68:7-21, 2017. e-Pub 2017. PMID: 28428103.
3. Kanagal-Shamanna R, Loghavi S, DiNardo CD, Medeiros LJ, Garcia-Manero G, Jabbour E, Routbort MJ, Luthra R, Bueso-Ramos CE, Khoury JD. Bone marrow pathologic abnormalities in familial platelet disorder with propensity for myeloid malignancy and germline RUNX1 mutation. Haematologica 102(10):1661-1670, 2017. e-Pub 2017. PMID: 28659335.
4. Gong Z, Medeiros LJ, Cortes JE, Zheng L, Khoury JD, Wang W, Tang G, Loghavi S, Luthra R, Yang W, Kantarjian HM, Hu S. Clinical and prognostic significance of e1a2 BCR-ABL1 transcript subtype in chronic myeloid leukemia. Blood Cancer J 7(7):e583, 2017. e-Pub 2017. PMID: 28708130.
5. Salem A, Loghavi S, Tang G, Huh YO, Jabbour EJ, Kantarjian H, Wang W, Hu S, Luthra R, Medeiros LJ, Khoury JD. Myeloid Neoplasms with Concurrent BCR-ABL1 and CBFB Rearrangements: A Series of 10 Cases of a Clinically Aggressive Neoplasm. Am J Hematol 92(6):520-528, 2017. e-Pub 2017. PMID: 28253536.
6. Salem A, Loghavi S, Khoury JD, Agbay RL, Jorgensen JL, Medeiros LJ. Herpes Simplex Infection Simulating Richter Transformation: A Series of Four Cases and Review of the Literature. Histopathology 70(5):821-831, 2017. e-Pub 2017. PMID: 27905140.
7. Thakral B, Medeiros LJ, Desai P, Lin P, Yin CC, Tang G, Khoury JD, Hu S, Xu J, Loghavi S, Hu B, Oki Y, Li S. Prognostic Impact of CD5 Expression in Diffuse Large B-cell Lymphoma in Patients Treated with Rituximab-EPOCH. Eur J Haematol 98(4):415-421, 2017. e-Pub 2017. PMID: 28039906.
8. Agbay RL, Torres-Cabala CA, Patel KP, Merril ED, Duvic M, Quesada A, Prieto VG, Aung PP, Loghavi S, Young KH, Hu S, Ferrufino-Schmidt MC, Tetzlaff M, Li S, Medeiros LJ, Miranda RN. Immunophenotypic Shifts in Primary Cutaneous γδ T-Cell Lymphoma Suggest Antigenic Modulation: A Study of Sequential Biopsy Specimens. Am J Surg Pathol 41(4):431-445, 2017. PMID: 28248813.
9. Loghavi S, Khoury JD. Langerhans cell histiocytosis in a patient with hairy cell leukemia: a tale of divergence. Blood 129(11):1563, 2017. PMID: 28302693.
10. Loghavi S, Wang SA, Medeiros LJ, Jorgensen JL, Li X, Xu-Monette ZY, Miranda RN, Young KH. Immunophenotypic and diagnostic characterization of angioimmunoblastic T-cell lymphoma by advanced flow cytometric technology. Leuk Lymphoma 57(12):1-9, 2016. e-Pub 2016. PMID: 27105079.
11. Loghavi S, Medeiros LJ. A rare histologic variant of a common lymphoma. Blood 128(25):3012, 2016. PMID: 28007735.
12. Agbay RL, Jain N, Loghavi S, Medeiros LJ, Khoury JD. Histologic transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma. Am J Hematol 91(10):1036-43, 2016. e-Pub 2016. PMID: 27414262.
13. Nomani L, Bodo J, Zhao X, Durkin L, Loghavi S, Hsi ED. CAL2 Immunohistochemical Staining Accurately Identifies CALR Mutations in Myeloproliferative Neoplasms. Am J Clin Pathol 146(4):431-8, 2016. PMID: 27686170.
14. Jain P, Verstovsek S, Wang W, Loghavi S, Torres HA, Estrov Z, Patel KP, Pemmaraju N. DNMT3A, TET2, and JAK2 mutations in polycythemia vera following long-term remission of secondary acute myeloid leukemia. Leuk Lymphoma 57(8):1-5, 2016. e-Pub 2015. PMID: 26700872.
15. Ballester LY, Loghavi S, Kanagal-Shamanna R, Barkoh BA, Lin P, Medeiros LJ, Luthra R, Patel KP. Clinical Validation of a CXCR4 Mutation Screening Assay for Waldenstrom Macroglobulinemia. Clin Lymphoma Myeloma Leuk 16(7):395-403.e1, 2016. e-Pub 2016. PMID: 27268124.
16. Khashab T, Loghavi S, Konoplev SN, Samaniego F. Resolution of lung adenocarcinoma after discontinuation of ibrutinib. BMJ Case Rep 2016, 2016. e-Pub 2016. PMID: 27435843.
17. Loghavi S, Routbort MJ, Patel KP, Luthra R, Wang WL, Broaddus RR, Davies MA, Lazar AJ. How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments?. J Natl Compr Canc Netw 14(6):787-92, 2016. PMID: 27283170.
18. Cao X, Medeiros LJ, Xia Y, Wang X, Thomas SK, Loghavi S, Li X, Shah JJ, Gustafson SA, Weber DM, Miranda RN, Xu-Monette ZY, Orlowski RZ, Young KH. Clinicopathologic Features and Outcomes of Lymphoplasmacytic Lymphoma Patients with Monoclonal IgG or IgA Paraprotein Expression. Leuk Lymphoma 57(5):1-27, 2016. e-Pub 2015. PMID: 26421453.
19. Aye le L, Loghavi S, Young KH, Siddiqi I, Yin CC, Routbort MJ, Liang M, Eilerman K, Medeiros LJ, Brynes RK, Bueso-Ramos C. Preleukemic phase of chronic myelogenous leukemia: morphologic and immunohistochemical characterization of 7 cases. Ann Diagn Pathol 21:53-8, 2016. e-Pub 2016. PMID: 27040932.
20. Loghavi S, Bueso-Ramos CE, Kanagal-Shamanna R, Ok CY, Salim AA, Routbort MJ, Mehrotra M, Verstovsek S, Medeiros LJ, Luthra R, Patel KP. Myeloproliferative neoplasms with calreticulin mutations exhibit distinctive morphologic features. Am J Clin Pathol 145(3):418-27, 2016. PMID: 27124925.
21. Deng L, Xu-Monette ZY, Loghavi S, Manyam GC, Xia Y, Visco C, Huh J, Zhang L, Zhai Q, Wang Y, Qiu L, Dybkær K, Chiu A, Perry AM, Zhang S, Tzankov A, Rao H, Abramson J, Sohani AR, Xu M, Hsi ED, Zhu J, Ponzoni M, Wang S, Li L, Zhang M, Ferreri AJ, Parsons BM, Li Y, Piris MA, Medeiros LJ, Young KH. Primary testicular diffuse large B-cell lymphoma displays distinct clinical and biological features for treatment failure in rituximab era: a report from the International PTL Consortium. Leukemia 30(2):361-72, 2016. e-Pub 2013. PMID: 26308769.
22. Agbay RL, Loghavi S, Medeiros LJ, Khoury JD. High-grade Transformation of Low-grade B-cell Lymphoma: Pathology and Molecular Pathogenesis. Am J Surg Pathol 40(1):e1-e16, 2016. PMID: 26658667.
23. Chihara D, Pro B, Loghavi S, Miranda RN, Medeiros LJ, Fanale MA, Hagemeister FB, Fayad LE, Romaguera JE, Samaniego F, Neelapu SS, Younes A, Fowler NH, Rodriguez MA, Wang M, Kwak LW, McLaughlin P, Dang NH, Oki Y. Phase II study of HCVIDD/MA in patients with newly diagnosed peripheral T-cell lymphoma. Br J Haematol 171(4):509-16, 2015. e-Pub 2015. PMID: 26260306.
24. Mehrotra M, Luthra R, Singh RR, Barkoh BA, Galbincea J, Mehta P, Goswami RS, Jabbar KJ, Loghavi S, Medeiros LJ, Verstovsek S, Patel KP. Clinical validation of a multipurpose assay for detection and genotyping of CALR mutations in myeloproliferative neoplasms. Am J Clin Pathol 144(5):746-55, 2015. PMID: 26486739.
25. Jain P, Verstovsek S, Loghavi S, Jorgensen JL, Patel KP, Estrov Z, Fayad L, Pemmaraju N. Durable remission with rituximab in a patient with an unusual variant of Castleman's disease with myelofibrosis-TAFRO syndrome. Am J Hematol 90(11):1091-2, 2015. e-Pub 2015. PMID: 25808231.
26. Yabe M, Medeiros LJ, Wang SA, Konoplev S, Ok CY, Loghavi S, Lu G, Flores L, Khoury JD, Cason RC, Young KH, Miranda RN. Clinicopathologic, Immunophenotypic, Cytogenetic, and Molecular Features of γδ T-Cell Large Granular Lymphocytic Leukemia: An Analysis of 14 Patients Suggests Biologic Differences With αβ T-Cell Large Granular Lymphocytic Leukemia. [corrected]. Am J Clin Pathol 144(4):607-19, 2015. PMID: 26386082.
27. Loghavi S, Al-Ibraheemi A, Zuo Z, Garcia-Manero G, Yabe M, Wang SA, Kantarjian HM, Yin CC, Miranda RN, Luthra R, Medeiros LJ, Bueso-Ramos CE, Khoury JD. TP53 overexpression is an independent adverse prognostic factor in de novo myelodysplastic syndromes with fibrosis. Br J Haematol 171(1):91-9, 2015. e-Pub 2015. PMID: 26123119.
28. Loghavi S, Kutok JL, Jorgensen JL. B-acute lymphoblastic leukemia/lymphoblastic lymphoma. Am J Clin Pathol 144(3):393-410, 2015. PMID: 26276770.
29. Loghavi S, Khoury JD, Medeiros LJ. Epstein-Barr virus-positive plasmacytoma in immunocompetent patients. Histopathology 67(2):225-34, 2015. e-Pub 2015. PMID: 25556356.
30. Loghavi S, Khoury JD. Disseminated blastic plasmacytoid dendritic cell neoplasm. Blood 126(4):558, 2015. PMID: 26421330.
31. Loghavi S, Alayed K, Aladily TN, Zuo Z, Ng SB, Tang G, Hu S, Yin CC, Miranda RN, Medeiros LJ, Khoury JD. Stage, age, and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients. J Hematol Oncol 8:65, 2015. e-Pub 2015. PMID: 26055271.
32. Cao X, Ye Q, Orlowski RZ, Wang X, Loghavi S, Tu M, Thomas SK, Shan J, Li S, Qazilbash M, Yin CC, Weber D, Miranda RN, Xu-Monette ZY, Medeiros LJ, Young KH. Waldenström macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis. J Hematol Oncol 8:74, 2015. e-Pub 2015. PMID: 26104577.
33. Yabe M, Tang G, Garcia-Manero G, Loghavi S, Lu X, Miranda RN, Medeiros LJ, Kantarjian HM, Bueso-Ramos CE, Khoury JD. Acute Myeloid Leukemia With t (v;5q33) Is Associated With Poor Overall Survival and Often Lacks Myelodysplastic Features. Clin Lymphoma Myeloma Leuk 15(15):Suppl:S85-90, 2015. PMID: 26297286.
34. Loghavi S, Pemmaraju N, Kanagal-Shamanna R, Mehrotra M, Medeiros LJ, Luthra R, Lin P, Huh Y, Kantarjian HM, Cortes JE, Verstovsek S, Patel KP. Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with CALR mutation and BCR-ABL1. Blood 125(21):3360-3, 2015. PMID: 25999449.
35. de la Garza Bravo MM, Patel KP, Loghavi S, Curry JL, Torres Cabala CA, Cason RC, Gangar P, Prieto VG, Medeiros LJ, Duvic M, Tetzlaff MT. Shared clonality in distinctive lesions of lymphomatoid papulosis and mycosis fungoides occurring in the same patients suggests a common origin. Hum Pathol 46(4):558-69, 2015. e-Pub 2014. PMID: 25666664.
36. Loghavi S, Khoury JD. Unusual breast mass: lymphoma with crystal-storing histiocytosis. Blood 125(15):2445, 2015. PMID: 26038772.
37. Zuo Z, Maiti S, Hu S, Loghavi S, Calin GA, Garcia-Manero G, Kantarjian HM, Medeiros LJ, Cooper LJ, Bueso-Ramos CE. Plasma circulating-microRNA profiles are useful for assessing prognosis in patients with cytogenetically normal myelodysplastic syndromes. Mod Pathol 28(3):373-82, 2015. e-Pub 2014. PMID: 25216221.
38. Loghavi S, Curry JL, Torres-Cabala CA, Ivan D, Patel KP, Mehrotra M, Bassett R, Prieto VG, Tetzlaff MT. Melanoma arising in association with blue nevus: a clinical and pathologic study of 24 cases and comprehensive review of the literature. Mod Pathol 27(11):1468-78, 2014. e-Pub 2014. PMID: 24743221.
39. Loghavi S, Zuo Z, Ravandi F, Kantarjian HM, Bueso-Ramos C, Zhang L, Singh RR, Patel KP, Medeiros LJ, Stingo F, Routbort M, Cortes J, Luthra R, Khoury JD. Clinical features of de novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations. J Hematol Oncol 7:74, 2014. e-Pub 2014. PMID: 25281355.
40. Pereira L, Petitt M, Fong A, Tsuge M, Tabata T, Fang-Hoover J, Maidji E, Zydek M, Zhou Y, Inoue N, Loghavi S, Pepkowitz S, Kauvar LM, Ogunyemi D. Intrauterine growth restriction caused by underlying congenital cytomegalovirus infection. J Infect Dis 209(10):1573-84, 2014. e-Pub 2014. PMID: 24403553.
41. Shah S, Loghavi S, Garcia-Manero G, Khoury JD. Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia. J Hematol Oncol 7:26, 2014. e-Pub 2014. PMID: 24669761.
42. Loghavi S, Walts AE, Bose S. CINtec® PLUS dual immunostain: a triage tool for cervical pap smears with atypical squamous cells of undetermined significance and low grade squamous intraepithelial lesion. Diagn Cytopathol 41(7):582-7, 2013. e-Pub 2012. PMID: 22833355.
43. Orakzai RH, Nalawadi S, Cuk O, Thomson L, Elad Y, Trento A, Siegel RJ, Loghavi S. Multimodality evaluation of a rare intracardiac tumor: cardiac hemangioma. Am J Med 124(8):e3-4, 2011. PMID: 21787898.
44. Loghavi S, Bose S. Polyomavirus infection and urothelial carcinoma. Diagn Cytopathol 39(7):531-5, 2011. e-Pub 2010. PMID: 20891007.
45. Graham KL, Zabel BA, Loghavi S, Zuniga LA, Ho PP, Sobel RA, Butcher EC. Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease. J Immunol 183(10):6717-23, 2009. e-Pub 2009. PMID: 19864606.
46. Fazli-Tabaei S, Yahyavi SH, Nouri M, Zartab H, Javid G, Loghavi S, Zarrindast MR. Dopamine receptor mechanism(s) and antinociception and tolerance induced by swim stress in formalin test. Behav Pharmacol 17(4):341-7, 2006. PMID: 16914952.

Book Chapters

1. Loghavi S, Tetzlaff MT. Primary cutaneous CD4+small/medium T-cell lymphoma. In: Hematopathology of the Skin: Clinical & Pathological Approach. Wolters Kluwer Health, 2016.
2. Loghavi S. Quantitative PCR for Plasma Epstein-Barr Virus Loads in Cancer Diagnostics. In: Methods Mol Biol, 51-61, 2016.
3. Hoehn D, Loghavi S. Laboratory Techniques Used in the Diagnosis of Pediatric Tumors. In: Pediatric Tumors: Pathology and Imaging. Springer: New York, 1-5, 2015.