Sandun Jayarathna Pahula Hewage, Ph.D., DABR

Peer-Reviewed Articles

1. Kaphle A, Jayarathna S, Cho SH. Deep learning based rapid X-ray fluorescence signal extraction and image reconstruction for preclinical benchtop X-ray fluorescence computed tomography applications. Sci Rep 15(1):19588, 2025. e-Pub 2025. PMID: 40467695.
2. Kaphle A, Jayarathna S, Krishnan S, Cho SH. Monte Carlo study of gold nanoparticle-mediated radiosensitization effects using nanoscale cell model combined with fractal-based DNA model. Med Phys 52(6):4605-4620, 2025. e-Pub 2025. PMID: 39928029.
3. Nepal N, Kaphle A, Jayarathna S, Cho SH. Monte Carlo Modeling of An Experimental Benchtop L-shell X-ray Fluorescence Imaging/CT System Adopting Two Silicone Drift Detectors. Nucl Instrum Methods Phys Res A 1072, 2025. e-Pub 2025. PMID: 40894265.
4. Jayarathna S, Kaphle A, Krishnan S, Cho SH. Nanoscale gold nanoparticle (GNP)-laden tumor cell model and its use for estimation of intracellular dose from GNP-induced secondary electrons. Med Phys 51(9):6276-6291, 2024. e-Pub 2024. PMID: 38935922.
5. Jayarathna S, Hoang M, Badkul R, Hoover A. Dosimetric impact of applicator displacement on three-dimensional image-guided high-dose-rate brachytherapy treatments for cervical cancer. J Contemp Brachytherapy 15(5):334-343, 2023. e-Pub 2023. PMID: 38026073.
6. Kaphle A, Jayarathna S, Moktan H, Aliru M, Raghuram S, Krishnan S, Cho SH. Deep Learning-Based TEM Image Analysis for Fully Automated Detection of Gold Nanoparticles Internalized Within Tumor Cell. Microsc Microanal 29(4):1474-1487, 2023. e-Pub 2023. PMID: 37488822.
7. Jayarathna S, Shen X, Chen RC, Li HH, Guida K. The effect of integrating knowledge-based planning with multicriteria optimization in treatment planning for prostate SBRT. J Appl Clin Med Phys 24(6):e13940, 2023. e-Pub 2023. PMID: 36827178.
8. Moktan H, Jayarathna S, Cho SH. Sensitivity enhancement of an experimental benchtop x-ray fluorescence imaging system by deploying a single crystal cadmium telluride detector system optimized for high flux x-ray operations. Nucl Instrum Methods Phys Res A 1025, 2022. e-Pub 2022. PMID: 35340930.
9. Jayarathna S, Moktan H, Cho SH. Use of the Fully Spectroscopic Pixelated Cadmium Telluride Detector for Benchtop X-Ray Fluorescence Computed Tomography. IEEE Access 10:105074-105083, 2022. e-Pub 2022. PMID: 36274671.
10. Jayarathna S, Ahmed MF, O'Ryan L, Moktan H, Cui Y, Cho SH. Characterization of a Pixelated Cadmium Telluride Detector System Using a Polychromatic X-Ray Source and Gold Nanoparticle-Loaded Phantoms for Benchtop X-Ray Fluorescence Imaging. IEEE Access 9:49912-49919, 2021. e-Pub 2021. PMID: 33996343.
11. Moktan H, Ahmed MF, Jayarathna S, Deng L, Cho SH. Monte Carlo study of x-ray detection configurations for benchtop x-ray fluorescence computed tomography of gold nanoparticle-loaded objects. Phys Med Biol 65(17):175010, 2020. e-Pub 2020. PMID: 32869750.
12. Jayarathna S, Ahmed, Md, Cho, SH. Geant4-based Model of a Mouse Injected with Gold Nanoparticles for X-Ray Tomography Simulation Studies. IEEE NANOMED, 2019. e-Pub 2019.
13. Jayarathna S, Ahmed Md, Cho SH. Fabrication and Testing of a Gold Nanoparticle-loaded Tissue-mimicking Phantom for Validation of Gold L -shell X-ray Fluorescence Imaging Results. IEEE NANOMED, 2019. e-Pub 2019.
14. Manohar N, Reynoso F, Jayarathna S, Moktan H, Ahmed MF, Diagaradjane P, Krishnan S, Cho SH. High-sensitivity imaging and quantification of intratumoral distributions of gold nanoparticles using a benchtop x-ray fluorescence imaging system. Opt Lett 44(21):5314-5317, 2019. e-Pub 2019. PMID: 31674996.
15. Deng L, Ahmed MF, Jayarathna S, Feng P, Wei B, Cho SH. A detector's eye view (DEV)-based OSEM algorithm for benchtop x-ray fluorescence computed tomography (XFCT) image reconstruction. Phys Med Biol 64(8):08NT02, 2019. e-Pub 2019. PMID: 30958796.
16. Jayarathna S, Manohar N, Ahmed MF, Krishnan S, Cho SH. Evaluation of dose point kernel rescaling methods for nanoscale dose estimation around gold nanoparticles using Geant4 Monte Carlo simulations. Sci Rep 9(1):3583, 2019. e-Pub 2019. PMID: 30837578.
17. Jayarathna S. Strangeness production in two-particle azimuthal correlations on the near and away side measured with ALICE in pp collisions at 7 TeV. Large Hadron Collider Physics, 2014. e-Pub 2014.
18. Wijesundera D, Jayarathna S, Bellwied R, Chu WK. A simulation study of antimatter-helium ion planar channeling in silicon. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2012. e-Pub 2012.

Abstracts

1. Jayarathna S, Hoover A, Clarke J, Badkul R. Clinical evaluation of dosimetric impact of applicator displacements on 3D gynecological high dose rate brachytherapy treatments. AAPM Annual Meeting, Poster, 2022. e-Pub 2022.
2. Jayarathna S, Reddy K, Li H, Guida K. Investigation of knowledge-based treatment planning models integrated with multi-Criteria Optimization for an upcoming clinical trial. AAPM Annual Meeting, Interactive e-Poster, 2022. e-Pub 2022.
3. Jayarathna S, Johnson D. A qualitative comparison of open-source toolkit for MLC trajectory log file analysis with commercially available software. AAPM MRV Chapter Annual Meeting, Oral presentation, 2022. e-Pub 2022.
4. Jayarathna S, Howard S, Johnson D. A Clinical Evaluation of An Open-Source Toolkit for TG-142 Based Monthly Imaging Quality Assurance Via Comparison with Commercial Software. AAPM Annual Meeting, Poster, 2021. e-Pub 2021.
5. Jayarathna S, Tailor R, Cho SH. A custom-made jig for in-air ionization chamber measurements and quality assurance of the Mark I-68 Cs-137 irradiator. AAPM Annual Meeting, Poster, 2020. e-Pub 2020.
6. Jayarathna S, Md A, Cho SH. Effect of Photon Incidence Angle on the Accuracy of the Dose Point Kernel Method for Calculation of Gold Nanoparticle-Mediated Intracellular Dose Enhancement. AAPM Annual Meeting, Oral presentation, 2020. e-Pub 2020.
7. Jayarathna S, Tailor R, Cho SH. An Ionization Chamber Mounting Jig for In-Air Output Calibration and Quality Assurance of Commercial Cs-137 Irradiators. AAPM Annual Meeting, Poster, 2019. e-Pub 2019.
8. Jayarathna S, Md A, Cho SH. Validation of Direct Gold L-Shell X-Ray Fluorescence Imaging Results Using a Tissue Mimicking Phantom Containing Gold Nanoparticles. AAPM Annual Meeting, Oral presentation, 2019. e-Pub 2019.
9. Jayarathna S. Ahmed Md, Cho SH. An Image-Based Mouse Model for Geant4 Monte Carlo Simulations of Multimodal Imaging with Benchtop X-Ray Fluorescence CT (XFCT) and Micro-CT. AAPM Annual Meeting, Oral presentation, 2018. e-Pub 2018.
10. Jayarathna S, Krishnan S, Cho SH. Development of a TEM Image-Based Cellular Geometry Model for Geant4 Monte Carlo Simulations of GNP-Mediated radio sensitization. AAPM Annual Meeting, Oral presentation, 2018. e-Pub 2018.
11. Jayarathna S, Manohar N, Cho SH. Application of the Dose Point Kernel Method for Nanoscale Dose Calculations Around Gold Nanoparticles. AAPM Annual Meeting, Oral presentation, 2017. e-Pub 2017.
12. Jayarathna S. Strange quark production in proton collisions at ALICE using azimuthal correlations. Quark Matter, Poster, 2014. e-Pub 2014.
13. Jayarathna S. Strange baryon vs meson ratio in near-side and away-side jets in proton collisions at ALICE using azimuthal correlations. APS April Meeting, Oral presentation, 2014. e-Pub 2014.
14. Jayarathna S. Jet-hadron azimuthal correlations in proton collisions at ALICE at √(S_NN ) = 7 TeV. Large Hadron Collider Physics, Poster, 2014. e-Pub 2014.