
Shubham Pant, M.D., MBBS
Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine
About Dr. Shubham Pant
Dr. Shubham Pant is a Professor in the Department of Gastrointestinal (GI) Medical Oncology with a joint appointment in the Department of Investigational Cancer Therapeutics (Phase I Center) at The University of Texas MD Anderson Cancer Center. Dr. Pant is recognized as an international expert in Gastrointestinal Cancers with an emphasis on Pancreatic and Biliary cancers and Phase 1 trials.
Dr. Pant’s research focuses on novel immunotherapeutic approaches and targeted therapies in GI cancers, including devising novel ways to target the KRAS mutation. He has been the lead/co-lead of several global practice-changing studies, including “Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01)”; “Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation”; and “Erdafitinib in patients with advanced solid tumors with FGFR alterations” These studies have led to FDA accelerated approval of Zanidatamab for HER2 overexpressing biliary tract cancer and the incorporation of Adagrasib into the NCCN guidelines for KRAS G12C advanced pancreatic cancer and biliary tract cancer.
He has over 150 peer-reviewed publications and has published in high-impact journals. His recent publications include:
• “Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial,” published in Nature Medicine.
• “Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study,” published in Lancet Oncology.
• “Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01): a multicentre, single-arm, phase 2b study,” published in Lancet Oncology.
• “Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation,” published in the Journal of Clinical Oncology.
He is frequently invited to present his research at national and international meetings and collaborates on numerous grants, including R01 and SPORE grants funded by the National Institute of Health. Dr. Pant serves on the National Cancer Institute (NCI) Pancreas Task Force and the Pancreatic Cancer Action Network’s (PanCan) Scientific and Medical Advisory Board. He also helped draft the American Society of Clinical Oncology (ASCO) Metastatic Pancreatic Cancer Guidelines, which provide evidence-based recommendations for physicians. He is also the editor of the book Pancreatic Cancer: Current Therapeutics and Future Directions (Publisher: Springer).
Dr. Pant completed his fellowship from the James Cancer Hospital/Solove Research Institute at the Ohio State University, where he was elected Chief Fellow. He has previously served as the Director of Clinical Trials, Section of Hematology/Oncology, and Associate Director of the TSET Phase I Program at the University of Oklahoma and was the recipient of the Mai Eager Anderson Endowed Chair in Cancer Clinical Trials. He was featured in "40 under 40" in Oklahoma magazine and has been voted by his peers as "America’s Top Doctors".
Dr. Pant has an interest in improving the quality of care for cancer patients, is a Lean Six Sigma Green Belt, and has served on the American Society of Clinical Oncology (ASCO) Quality of Care Committee and ASCO's International Quality Task Force. Dr. Pant was also selected for the prestigious ASCO Leadership Development Program.
Dr. Pant’s dedication to professionalism was recognized by the APEX Award for Professional Excellence sponsored by the MD Anderson Center for Professionalism Support and Success. This award recognizes faculty members who show best practices in professional behavior and foster a supportive workplace culture. His nominators described him as someone whose “kindness and empathy make a significant difference in the lives of those he treats, with his supportive nature creating a positive and uplifting work environment.”
For his patient care, he was awarded the Golden Pillar Award for Outstanding Patient Service twice for achieving patient satisfaction scores in the top 90th percentile as measured by the OU Medicine EXCEL initiative and was awarded for being in the top 1% of patient satisfaction across the country in 2024.
In his free time, Dr. Pant enjoys writing and has contributed to the Huffington Post India. He is the author of the bestselling book published by Harper Collins, India: Food Matters: The Role Your Diet Plays in the Fight Against Cancer.
Present Title & Affiliation
Primary Appointment
Professor, Department of Gastrointestinal (GI) Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Director Clinical Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Gastrointestinal (GI) Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2007 | Maulana Azad Medical College, New Delhi, IN, MD |
Postgraduate Training
2005-2008 | Clinical Fellowship, Hematology Oncology, The Ohio State University, Columbus, Ohio |
2002-2005 | Clinical Fellowship, Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma |
Licenses & Certifications
2008 | Diplomate of the American Board of Internal Medicine in Medical Oncology |
2008 | Diplomate of the American Board of Internal Medicine in Hematology |
2005 | Diplomate of the American Board of Internal Medicine |
Experience & Service
Faculty Academic Appointments
Associate Professor, Department of Gastrointestinal (GI) Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2022
Associate Professor, Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2022
The Mai Eager Anderson Chair in Cancer Clinical Trials, OUHSC, Oklahoma City, OK, 2015
Associate Professor, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2014 - 2016
Associate Director, Department of TSET Phase 1 Program, Peggy and Charles Oklahoma Cancer Center, Oklahoma City, OK, 2010 - 2016
Assistant Professor, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2008 - 2014
Director of Clinical Trials, Section Of Hematology-Oncology, Department of Section of Hematology-Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2008 - 2016
Administrative Appointments/Responsibilities
Clinical Lead Due Diligence Oschner Network, The University of Texas MD Anderson Cancer Center, Houston, 2020 - Present
Associate Director, Department of Sheihk Ahmed Center for Early Phase Drug Development of Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - Present
Clinical Lead, Tyler, UT, The University of Texas MD Anderson Cancer Center, Houston, 2018 - 2019
Research Liaison, Department of Protocol Review, Integration & Strategic Management (PRISM), The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2018
Oncology Lead (CRDSG), Department of GI Cancers, OUHSC, Oklahoma City, OK, 2012 - Present
Institutional Principal Investigator, CALGB & ACTION, OUHSC, Oklahoma City, OK, 2010 - 2013
Other Professional Positions
GI-ICT Liaison Group, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - Present
Advisory Board, Bayer, Germany, 2015
Advisory Board, Halozyme, San Diego, California, 2015
Advisory Board, Celgene, Summit, New Jersey, 2014
Multicultural Advisory Committee, OU Physicians, Oklahoma City, OK, 2013 - 2015
Advisory Board, Marshall Edwards, Cleveland, Ohio, 2012
Fellowship Recruitment Committee, The Ohio State University, Columbus, OH, 2007 - 2008
Inpatient Medical Working Group Committee, The Ohio State University, Columbus, OH, 2007 - 2008
Institutional Committee Activities
Member, Clinical/Scientific Review Committee, 2018 - Present
Member, Epic Working Group, 2016 - 2018
Member, Clinical/Scientific Review Committee, 2016 - 2017
Member, Scientific Review Committee -Oklahoma University Health Sciences Center, 2009 - 2016
Member, Institutional Review Board (IRB). Oklahoma University Health Sciences Center, 2008 - 2009
Member, Clinical Trials Committee - Oklahoma University Health Sciences Center, 2008 - 2016
Honors & Awards
2021 | Chair “Now and Next in Pancreatic Cancer” , Educational Session, ASCO Annual Meeting |
2021 - 2024 | National Cancer Institute (NCI) Pancreas Task Force |
2020 - 2024 | ASCO Gastrointestinal Cancer Guideline Advisory Group |
2020 - 2024 | Co-lead, FDA-OCE's Eligibility Criteria Consistency Initiative |
2019 - 2024 | ASCO Annual Meeting Educational Committee.GI-Non Colorectal Track |
2019 - 2024 | ASCO International Quality Task Force |
2019 - 2024 | DoCM Fastest PI, Clinical Trial Activation, UTMD Anderson Cancer Center |
2019 | ASCO Metastatic Pancreatic Cancer Guideline Update |
2016 - 2019 | ASCO Quality Committee, ASCO |
2015 - 2016 | ASCO Leadership Development Program |
2015 | Chair, The Mai Eager Anderson Chair in Cancer Clinical Trials |
2015 | Lean/Six Sigma Green Belt Certification, OU College Of Engineering |
2015 | Oklahoma “40 under 40”, Oklahoma Magazine |
2013 | Top Clinical Trials Accrual GI cancer Program, The Stephenson Cancer Center |
2012 | Golden Pillar Award for Outstanding Patient Service for achieving patient satisfaction scores in the top 95th percentile as measured by the OU Medicine EXCEL initiative |
2008 | Plaque of Merit for Dedicated Service awarded by the Department of Hematology-Oncology, Ohio State University Medical Center |
2007 - 2008 | Elected Chief Fellow, Division of Hematology and Oncology James Cancer Hospital and Solove Research Institute, Department of Medicine, Ohio State University |
2006 | Recipient of ASCO/AACR Workshop award for Methods in Clinical Cancer Research |
2004 | First prize for original research at Stuart Wolf Day, Department of Medicine, OUHSC |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2019. Multidisciplinary Therapy of Pancreas Cancer: Recent Advances and Emerging Paradigms Landscape of Phase 1 Studies. Conference. UTMD ANDERSON. HOUSTON, TX, US.
Regional Presentations
- 2015. Clinical Trials and New Therapeutic Strategies in Pancreatic Cancer, 12th Annual Garden Walk for Hope & Awareness: Oklahoma Pancreatic Cancer Support Group. Conference. OUHSC, US.
- 2014. Pancreatic Cancer. Conference. OUHSC, US.
- 2014. Introduction to Clinical Trials. Conference. OUHSC, US.
- 2014. The Neutropenic Patient. Conference. OUHSC, US.
- 2013. Clinical Trials in the fight against cancer. Conference. OU Campus. Norman, OK, US.
- 2013. Pancreatic Cancer: Adjuvant and Metastatic Treatment. Conference. OUHSC, US.
- 2012. Clinical Trials and New Therapeutic Strategies in Pancreatic Cancer, 8th Annual Garden Walk for Hope & Awareness: Oklahoma Pancreatic Cancer Support Group. Conference. OUHSC, US.
- 2012. Pancreatic Cancer Research, Keynote Speaker. Conference. John F. Henry Memorial Golf Tournament, Cherokee Hills Golf Course. Tulsa, OK, US.
- 2011. Update of New Treatment Strategies and Clinical Trials, 7th Annual Garden Walk for Hope & Awareness: Oklahoma Pancreatic Cancer Support Group. Conference. OUHSC, US.
- 2011. Update on the Treatment of Gastrointestinal Malignancies. Conference. Stephenson Oklahoma Cancer Center. Oklahoma City, OK, US.
- 2010. Update on Pancreatic Cancer, 6th annual garden walk for hope & awareness: Oklahoma pancreatic cancer support group. Conference. OUHSC, US.
- 2010. Clinical Trials In Oncology: History and the road ahead. Conference. OUHSC, US.
- 2009. Treatment of Pancreatic Cancer: Recent advances and future challenges, 5th annual garden walk for hope & awareness: Oklahoma pancreatic cancer support group. Conference. OUHSC, US.
- 2009. Acute pain management. Conference. OUHSC. Oklahoma City, OK, US.
- 2009. Chemotherapy in the twenty first century: Towards a personalized approach. Conference. Edmond Regional Medical Center. Edmond, OK, US.
- 2009. Targeted Therapy for Cancer: Recent Developments and Future Challenges. Conference. Norman Regional Hospital. Norman, OK, US.
- 2009. Clinical Trial Conference with presentations including accrual, new or challenging trials and topics related to clinical trials and drug development. Conference. OUHSC, US.
National Presentations
- 2020. A phase I/II study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitors. Conference. SITC, US.
- 2020. Safety and efficacy signals in the complete phase I study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitors (ICIs). Conference. SITC, US.
- 2019. Poster:The use of biomarkers and ctDNA in a phase 1 trial of ARQ 751. Conference. NCI-EORTC-AACR, US.
- 2018. Results of a phase I dose escalation study of ARQ 751 in adult subjects with advanced solid tumors with AKT1, 2, 3 genetic alterations, activating PI3K mutations, PTEN-null, or other known actionable. Conference. AACR Annual Meeting, US.
- 2008. Incidence of late failure following myeloablative conditioning with BuCy2 and matched sibling allogeneic stem cell transplantation for acute myeloid leukemia. Conference. 50th ASH Annual Meeting. San Francisco, CA, US.
- 2006. Long-term follow-up of treatment for acute myeloid leukemia with allogeneic hematopoetic cell transplantation using BuCy2 as preparation. Conference. American Society of Hematology 48th Annual Meeting & Exposition. Orlando, FL, US.
International Presentations
- 2021. Educational Session: Integration of Next-Generation Sequencing Into the Clinic for Pancreatic Cancer. Invited. ASCO Annual Meeting, US.
- 2020. Tyme-88-Panc Part 2: A randomized phase II/III of SM-88 with MPS as third-line in metastatic PDAC. Conference. ASCO GI. San Francisco, US.
- 2020. Erdafitinib for advanced solid tumors: A phase 2, open-label efficacy and safety study in adult and adolescent patients (pts) with advanced solid tumors harboring fibroblast growth factor receptor (FGFR) gene alterations. Conference. ASCO GI. San Francisco, US.
- 2020. Immunotherapy in Colorectal Cancer. Invited. Apollo Cancer Conclave. Hyderabad, IN.
- 2020. Locally Advanced Pancreatic Cancer – Current Management. Invited. Apollo Cancer Conclave. Hyderabad, IN.
- 2019. A phase I/II study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients who have progressed on prior anti-PD-1 therapy. Conference. ASCO Annual Meeting, US.
- 2019. Actionable mutations and targeted therapy in GI cancers. Conference. Apollo Cancer Conclave. Chennai, IN.
- 2019. Oral Presentation: A phase I dose escalation (DE) study of ERK inhibitor, LY3214996, in advanced (adv) cancer (CA) patients. Conference. ASCO Annual Meeting. Chicago, US.
- 2019. Neoadjuvant therapy in Pancreas. Invited. Apollo Cancer Conclave. Chennai, IN.
- 2018. Neoadjuvant Therapies for Pancreatic Cancer. Invited. 2018 ONCO HPB, BR.
- 2018. Poster:Results of a phase I dose escalation study of ARQ 751 in adult subjects with advanced solid tumors with AKT1, 2, 3 genetic alterations, activating PI3K mutations, PTEN-null, or other known actionable PTEN mutations. Conference. NCI-EORTC-AACR. Brussels, BE.
- 2018. Evaluation of the spectrum selective RTK inhibitor sitravatinib in clear cell renal cell carcinoma (ccRCC) refractory to anti-angiogenic therapy (AAT). Conference. ASCO Annual Meeting. Chicago, US.
- 2017. Poster:Proof-of concept phase I study of everolimus, letrozole and trastuzumab in hormone receptor-positive, HER2-positive/amplified or mutant metastatic breast cancer or other solid tumors: Evaluating synergy and overcoming resistance. Conference. ASCO. Chicago, US.
- 2016. Collection and utilization of oncology big data. Invited. ASCO Annual Meeting. Chicago, US.
- 2015. A phase II study of the c-Met inhibitor tivantinib (tiv) in combination with FOLFOX for the treatment of patients (pts) with previously untreated metastatic adenocarcinoma of the distal esophagus, gastroesophageal (GE) junction, or stomach. Conference. 2015 ASCO Annual Meeting. Chicago, US.
- 2014. Utility of 18F-flourodeoxyglucose positron emission tomography (FDG-PET) to predict resectability after neoadjuvant therapy in patients with unresectable pancreatic cancer on CT scans. Conference. 2014 ASCO Gastrointestinal Cancers Symposium. San Francisco, US.
- 2013. Phase I study of the HSP90 inhibitor AUY922 in combination with capecitabine as treatment for patients with advanced solid tumors. Conference. 2013 ASCO Annual Meeting. Chicago, US.
- 2012. ME-143, a novel inhibitor of tumor-specific NADH oxidase (tNOX): Results from a first-in-human phase I study. Conference. 2012 ASCO Annual Meeting. Chicago, US.
- 2012. A first-in-human phase I study of the oral Notch inhibitor LY900009 in patients with advanced cancer. Invited. 2012 ASCO Annual Meeting. Oral Presentation. Chicago, US.
- 2011. Phase 1b results of c-MET inhibitor ARQ 197 in combination with gemcitabine in a cohort of patients (pts) with advanced breast, ovarian, and uterine tumors. Conference. 2011 ASCO Annual Meeting. Chicago, US.
- 2010. Phase 1b dose escalation trial evaluating c-Met inhibitor ARQ 197 and Gemcitabine in patients (pts) with advanced solid tumors on schedules refined by in vitro mechanistic studies. Conference. 35th European Society of Medical Oncology (ESMO) Congress, IT.
- 2009. Colon and rectal cancer gene expression profiles: Results from the analysis of samples in Expression Project for Oncology (expO) database. Conference. 2009 ASCO Gastrointestinal Cancers Symposium. San Francisco, US.
Grant & Contract Support
Date: | 2024 - 2030 |
Title: | A Phase 1 Dose Escalation and Expansion Study of EO-3021, an Anti-claudin 18.2 (CLDN18.2) Antibody Drug Conjugate, in Patients with Solid Tumors Likely to Express CLDN18.2 (ELVCAP-002-01) |
Funding Source: | Elevation Oncology, Inc |
Role: | PI |
ID: | 2023-0520 | PID15804 |
Date: | 2023 - 2030 |
Title: | Phase 1a/1b, Open-label dose-finding trial to explore safety, pharmacokinetics, pharmacodynamics, and efficacy of BI 3706674 given orally as monotherapy in patients with unresectable metastatic KRAS wild type amplified gastric, oesophageal, and gastroesophageal-junction adenocarcinoma |
Funding Source: | BOEHRINGER INGELHEIM PHARM INC |
Role: | Principal Investigator-MDACC |
ID: | 2023-0574 | PID15826 |
Date: | 2023 - 2028 |
Title: | MD Anderson Epigenetics SPORE – Project 003 “Enhancing adoptive T cell therapy via targeting the epigenome” |
Funding Source: | NIH/NCI |
Role: | Co-Program Leader |
ID: | FP17549 |
Date: | 2023 - 2030 |
Title: | Phase 1b/2, dose-escalation, randomized, multicenter study of maintenance Ivaltinostat plus Capecitabine or Capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on first line FOLFIRINOX chemotherapy |
Funding Source: | CG Pharmaceuticals, Inc |
Role: | PI |
ID: | 2022-0503 | PID14585 |
Date: | 2020 - 2021 |
Title: | NO TITLE PROVIDED |
Funding Source: | Precision Promise, PanCan |
Role: | PI |
ID: | 000011964 / MDA-010-2020 |
Date: | 2019 - 2024 |
Title: | Adoptive T Cell Therapy for Pancreatic Cancer |
Funding Source: | NIH/NCI |
Role: | Co-I |
ID: | 1R01CA237672-0 |
Date: | 2019 - 2024 |
Title: | Project 3 |
Funding Source: | SPORE in Gastrointestinal Cancer |
Role: | Clinical Co-Leader |
ID: | IP50CA221707-01 |
Date: | 2018 - 2019 |
Title: | Adoptive Transfer of TGF-B Resistant TIL to Defeat Immunosuppressive PDAC |
Funding Source: | Stand Up to Cancer |
Role: | Sub-investigator |
ID: | SSU2C-AACR-PCC-03-18 |
Date: | 2017 - 2019 |
Title: | Molecular Epidemiology of Gallbladder Cancer |
Funding Source: | Sister Institution Network Fund Scientific Review Committee |
Role: | PI |
Date: | 2007 - 2008 |
Title: | Clinical Research Grant |
Funding Source: | Amgen |
Role: | PI |
Title: | MD Anderson Cancer Center and 4D Pharma Plc |
Funding Source: | Alliance |
Role: | PI |
ID: | 2018-2023 |
Title: | Tele-PancFit: A multi-site trial of remotely supervised, home-based exercise prehabilitation during pancreatic cancer chemotherapy |
Funding Source: | NIH/NCI |
Role: | Co-I |
ID: | U01 CA271373-01 |
Selected Publications
Peer-Reviewed Articles
- Grewal, K, Pant, S, Hu, I, Eluri, M, An, AW, Serpas Higbie, V, Huey, RW, Kasab, A, Javle, M, Lee, S. CLO25-099. Journal of the National Comprehensive Cancer Network : JNCCN 23(35), 2025. e-Pub 2025. PMID: 40154395.
- Ahmed, J, Knisely, A, Torrado, C, Stephen, B, Yang, Y, Song, J, Alshawa, A, Zarifa, A, Jhingran, A, Koay, EJ, Morris, VK, Javle, M, Wolff, RA, Meric-Bernstam, F, Pant, S, Rodon Ahnert, J, Naing, A. A phase I/II trial of avelumab combinations with ivuxolimab, utomilumab, and radiation therapy in patients with advanced gastrointestinal malignancies. Oncologist 30(3), 2025. e-Pub 2025. PMID: 40139261.
- Rajdev, L, King, G, Lieu, C, Cohen, S, Pant, S, Uboha, NA, Deming, DA, Malla, M, Kasi, A, Klute, K, Spencer, K, Dasari, NV, Morris, VK, Botta, G, Lowy, AM, O'Hara, MH, Eads, JR, King, DA, Shah, MA, Hong, TS, Parikh, AR, Klempner, SJ, Jabbour, SK, Chawla, A, Molena, D, George, TJ, Gibson, MK, Allegra, C, Goodman, KA, Eng, C, Philip, PA. Incorporating Circulating Tumor DNA Testing Into Clinical Trials. JCO Precision Oncology 9, 2025. e-Pub 2025. PMID: 40048671.
- Demirdjian, L, Triantos, S, Standish, K, Thomas, S, Xia, Q, Zhang, J, Greshock, J, Paone, J, Sheridan, P, Pant, S, Massard, C, Reardon, DA, Loriot, Y, Schuler, M, Sweiti, H. Prognostic Impact of Oncogenic Fibroblast Growth Factor Receptor Alterations in Patients With Advanced Solid Tumors in a Real-World Setting. Cancer medicine 14(4), 2025. e-Pub 2025. PMID: 40007233.
- Yousef, M, Hurd, MW, Yousef, A, Ludmir, EB, Balachandran Pillai, A, Peterson, J, Koay, EJ, Albarouki, S, Tzeng, CW, Snyder, RA, Katz, MH, Wang, H, Overman, MJ, Maitra, A, Pant, S, Smaglo, BG, Wolff, RA, Yao, JC, Shen, JY, Zhao, D. Clinical and molecular characteristics of patients with brain metastasis secondary to pancreatic ductal adenocarcinoma. Oncologist 30(1), 2025. e-Pub 2025. PMID: 39014543.
- Wainberg, ZA, Melisi, D, Macarulla, T, Pazo-Cid, R, Chandana, SR, De La Fouchardiere, C, Dean, A, Kiss, I, Jin Leei, W, Goetze, TO, Van Cutsem, E, Paulson, AS, Bekaii-Saab, T, Pant, S, Hubner, RA, Xiao, Z, Chen, H, Benzaghou, F, O'Reilly, EM. A plain language summary of NALIRIFOX compared with nab-paclitaxel and gemcitabine for patients with metastatic pancreatic cancer (NAPOLI 3). Future Oncology 21(7):765-774, 2025. e-Pub 2025. PMID: 39935331.
- Chen, JJ, Vincent, MY, Shepard, D, Peereboom, D, Mahalingam, D, Battiste, JD, Patel, MR, Juric, D, Wen, PY, Bullock, AJ, Selfridge, JE, Pant, S, Liu, J, Li, W, Fyfe, S, Wang, S, Zota, V, Mahoney, J, Watnick, RS, Cieslewicz, M, Watnick, J. Phase 1 dose expansion and biomarker study assessing first-in-class tumor microenvironment modulator VT1021 in patients with advanced solid tumors. Communications Medicine 4(1), 2024. e-Pub 2024. PMID: 38773224.
- Yousef, A, Yousef, M, Chowdhury, S, Abdilleh, K, Knafl, M, Edelkamp, P, Alfaro-Munoz, KD, Chacko, R, Peterson, J, Smaglo, BG, Wolff, RA, Pant, S, Lee, MS, Willis, JA, Overman, MJ, Doss, S, Matrisian, L, Hurd, MW, Snyder, RA, Katz, MH, Wang, H, Maitra, A, Shen, JP, Zhao, D. Impact of KRAS mutations and co-mutations on clinical outcomes in pancreatic ductal adenocarcinoma. npj Precision Oncology 8(1), 2024. e-Pub 2024. PMID: 38310130.
- Ludmir, EB, Sherry, AD, Fellman, B, Liu, S, Bathala, TK, Haymaker, CL, Medina-Rosales, M, Reuben, A, Holliday, EB, Smith, GL, Noticewala, SS, Nicholas, S, Price, TR, Martin, RM, Perles, LA, Lee, SS, Lee, MS, Smaglo, BG, Huey, RW, Willis, JA, Zhao, D, Cohen, L, Taniguchi, C, Koay, EJ, Katz, MH, Wolff, RA, Das, P, Pant, S, Koong, A, Tang, C. Addition of Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic Pancreatic Ductal Adenocarcinoma (EXTEND). Journal of Clinical Oncology 42(32):3795-3805, 2024. e-Pub 2024. PMID: 39102622.
- Dilly, J, Hoffman, MT, Abbassi, L, Li, Z, Paradiso, F, Parent, BD, Hennessey, CJ, Jordan, AC, Morgado, M, Dasgupta, S, Uribe, GA, Yang, A, Kapner, KS, Hambitzer, FP, Qiang, L, Feng, H, Geisberg, J, Wang, J, Evans, KE, Lyu, H, Schalck, A, Feng, N, Lopez, AM, Bristow, C, Kim, M, Rajapakshe, K, Bahrambeigi, V, Roth, JA, Garg, K, Guerrero, PA, Stanger, BZ, Cristea, S, Lowe, SW, Baslan, T, Van Allen, EM, Mancias, JD, Chan, E, Anderson, A, Katlinskaya, Y, Shalek, A, Hong, DS, Pant, S, Hallin, J, Anderes, K, Olson, P, Heffernan, TP, Chugh, S, Christensen, JG, Maitra, A, Wolpin, BM, Raghavan, S, Nowak, JA, Winter, PS, Dougan, SK, Aguirre, AJ. Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer. Cancer discovery 14(11):2135-2161, 2024. e-Pub 2024. PMID: 38975874.
- Balachandran Pillai, A, Yousef, M, Yousef, A, Alfaro-Munoz, KD, Smaglo, BG, Willis, JA, Wolff, RA, Pant, S, Hurd, MW, Maitra, A, Wang, H, Katz, MH, Prakash, L, Tzeng, CD, Snyder, RA, Castelnovo, LF, Chen, A, Kravets, A, Kudriavtseva, K, Tarasov, A, Kryukov, K, Ying, H, Shen, JY, Zhao, D. Molecular and Clinical Features of Pancreatic Acinar Cell Carcinoma. Cancers 16(19), 2024. e-Pub 2024. PMID: 39410042.
- Pant, S, Cho, BC, Kyriakopoulos, CE, Spira, AI, Tannir, NM, Werner, TL, Yan, X, Neuteboom, S, Chao, RC, Goel, S. Targeting multiple receptor tyrosine kinases with sitravatinib. Investigational New Drugs 42(5):547-558, 2024. e-Pub 2024. PMID: 39168901.
- Wainberg, ZA, Bekaii-Saab, T, O'Reilly, EM, Pant, S. Starting at the Front Line in Metastatic Pancreatic Cancers As New Options Emerge, How Do You Select and Sequence?. Oncology (United States) 38(9):352-354, 2024. e-Pub 2024.
- Ngoi, NY, Tang, TY, Gaspar, CF, Pavlick, D, Buchold, G, Scholefield, EL, Parimi, V, Huang, RS, Janovitz, T, Danziger, N, Levy, M, Pant, S, De Armas, AD, Kumpula, D, Ross, JS, Javle, M, Rodon Ahnert, J. Methylthioadenosine Phosphorylase Genomic Loss in Advanced Gastrointestinal Cancers. Oncologist 29(6):493-503, 2024. e-Pub 2024. PMID: 38330461.
- Ahmed, J, Stephen, B, Yang, Y, Kwiatkowski, E, Ejezie, CL, Pant, S. Phase Ib/II Study of Lacnotuzumab in Combination with Spartalizumab in Patients with Advanced Malignancies. Journal of Immunotherapy and Precision Oncology 7(2):73-81, 2024. e-Pub 2024. PMID: 38721402.
- DiPeri, TP, Evans, KW, Wang, B, Zhao, M, Akcakanat, A, Raso, G, Rizvi, YQ, Zheng, X, Korkut, A, Varadarajan, K, Uzunparmak, B, Ileana Dumbrava, EE, Pant, S, Ajani, JA, Pohlmann, PR, Jensen, VB, Javle, M, Rodon Ahnert, J, Meric-Bernstam, F. Co-clinical Trial of Novel Bispecific Anti-HER2 Antibody Zanidatamab in Patient-Derived Xenografts. Cancer discovery 14(5):828-845, 2024. e-Pub 2024. PMID: 38358339.
- Subbiah, V, Coleman, N, Piha-Paul, SA, Tsimberidou, AM, Janku, F, Rodon Ahnert, J, Pant, S, Ileana Dumbrava, EE, Fu, S, Hong, DS, Zhang, S, Sun, M, Jiang, Y, Roszik, J, Song, J, Yuan, Y, Meric-Bernstam, F, Naing, A. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies. Cancer Research Communications 4(2):378-387, 2024. e-Pub 2024. PMID: 38126764.
- Amaria, RN, Knisely, A, Vining, D, Kopetz, S, Overman, MJ, Javle, M, Antonoff, MB, Tzeng, CD, Wolff, RA, Pant, S, Lito, K, Rangel, KM, Fellman, B, Yuan, Y, Lu, KH, Sakellariou-Thompson, D, Haymaker, CL, Forget, MA, Hwu, P, Bernatchez, C, Jazaeri, AA. Efficacy and safety of autologous tumor-infiltrating lymphocytes in recurrent or refractory ovarian cancer, colorectal cancer, and pancreatic ductal adenocarcinoma. Journal for immunotherapy of cancer 12(2), 2024. e-Pub 2024. PMID: 38309721.
- Pant S, Wainberg ZA, Weekes CD, Furqan M, Kasi PM, Devoe CE, Leal AD, Chung V, Basturk O, VanWyk H, Tavares AM, Seenappa LM, Perry JR, Kheoh T, McNeil LK, Welkowsky E, DeMuth PC, Haqq CM, O'Reilly EM. Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial. Nat Med 30(2):531-542, 2024. e-Pub 2024. PMID: 38195752.
- Cecchini M, Cleary JM, Shyr Y, Chao J, Uboha N, Cho M, Shields A, Pant S, Goff L, Spencer K, Kim E, Stein S, Kortmansky JS, Canosa S, Sklar J, Swisher EM, Radke M, Ivy P, Boerner S, Durecki DE, Hsu CY, LoRusso P, Lacy J. NCI10066: a Phase 1/2 study of olaparib in combination with ramucirumab in previously treated metastatic gastric and gastroesophageal junction adenocarcinoma. Br J Cancer 130(3):476-482, 2024. e-Pub 2024. PMID: 38135713.
- Bazhenova, LA, Kim, DW, Cho, BC, Goel, S, Heist, RS, Werner, TL, Eaton, K, Wang, JS, Pant, S, Adkins, D, Blakely, CM, Yan, X, Neuteboom, S, Christensen, JG, Chao, RC, Bauer, TM. Sitravatinib in patients with solid tumors selected by molecular alterations. Future Oncology 20(39):3213-3227, 2024. e-Pub 2024. PMID: 39513224.
- Harding, JJ, Fan, J, Oh, DY, Choi, HJ, Kim, JW, Chang, HM, Bao, L, Sun, HC, Macarulla, T, Xie, F, Metges, JP, Ying, J, Bridgewater, J, Lee, MA, Tejani, MA, Chen, EY, Kim, D, Wasan, H, Ducreux, M, Bao, Y, Lindsey, S, Bachini, M, Morement, H, Boyken, L, Ma, J, Garfin, P, Pant, S. A plain language summary of the results from the phase 2b HERIZON-BTC-01 study of zanidatamab in participants with HER2-amplified biliary tract cancer. Future Oncology 20(31):2319-2329, 2024. e-Pub 2024. PMID: 39114870.
- Surana R, Gonzalez GN, Rogers J, Hong DS, Yap TA, Rodon J, Naing A, Wolff RA, Smaglo BG, Bernstam FM, Subbiah V, Pant S. Utility of Established Prognostic Scoring Systems for Patients with Advanced Pancreatic Adenocarcinoma Enrolled in Immunotherapy-Based Early-Phase Clinical Trials. J Gastrointest Cancer 54(4):1308-1315, 2023. e-Pub 2023. PMID: 37119430.
- Taniguchi, C, Frakes, JM, Aguilera, T, Palta, M, Czito, BG, Bhutani, M, Colbert, LE, Abi Jaoude, J, Bernard, V, Pant, S, Tzeng, CD, Kim, DW, Malafa, M, Costello, J, Mathew, GG, Rebueno, N, Koay, EJ, Das, P, Ludmir, EB, Katz, MH, Wolff, RA, Beddar, S, Sawakuchi, GO, Moningi, S, Slack Tidwell, RS, Yuan, Y, Thall, PF, Beardsley, RA, Holmlund, J, Herman, JM, Hoffe, S. Stereotactic body radiotherapy with or without selective dismutase mimetic in pancreatic adenocarcinoma. The lancet oncology 24(12):1387-1398, 2023. e-Pub 2023. PMID: 38039992.
- Nelson BE, Tsimberidou AM, Fu X, Fu S, Subbiah V, Sood AK, Rodon J, Karp DD, Blumenschein G, Kopetz S, Pant S, Piha-Paul SA. A Phase I Trial of Bevacizumab and Temsirolimus in Combination With Valproic Acid in Advanced Solid Tumors. Oncologist 28(12):e1100-e1292, 2023. e-Pub 2023. PMID: 37311055.
- Wainberg, ZA, Melisi, D, Macarulla, T, Pazo-Cid, R, Chandana, SR, De La Fouchardiere, C, Dean, A, Kiss, I, Lee, WJ, Goetze, TO, Van Cutsem, E, Paulson, AS, Bekaii-Saab, T, Pant, S, Hubner, RA, Xiao, Z, Chen, H, Benzaghou, F, O'Reilly, EM. NALIRIFOX versus nab-paclitaxel and gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (NAPOLI 3). The Lancet 402(10409):1272-1281, 2023. e-Pub 2023. PMID: 37708904.
- Bekaii-Saab TS, Yaeger R, Spira AI, Pelster MS, Sabari JK, Hafez N, Barve M, Velastegui K, Yan X, Shetty A, Der-Torossian H, Pant S. Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation. J Clin Oncol 41(25):101200JCO2300434, 2023. e-Pub 2023. PMID: 37099736.
- Lee MS, Kaseb AO, Pant S. The emerging role of circulating tumor DNA in non-colorectal gastrointestinal cancers. Clin Cancer Res 29(17):3267-3274, 2023. e-Pub 2023. PMID: 37092904.
- Pant S, Schuler M, Iyer G, Witt O, Doi T, Qin S, Tabernero J, Reardon DA, Massard C, Minchom A, Lugowska I, Carranza O, Arnold D, Gutierrez M, Winter H, Stuyckens K, Crow L, Najmi S, Hammond C, Thomas S, Santiago-Walker A, Triantos S, Sweiti H, Loriot Y, Investigators R. Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study. Lancet Oncol 24(8):925-935, 2023. e-Pub 2023. PMID: 37541273.
- Yousef A, Yousef M, Chowdhury S, Abdilleh K, Knafl M, Edelkamp P, Alfaro-Munoz K, Chacko R, Peterson J, Smaglo BG, Wolff RA, Pant S, Lee MS, Willis J, Overman M, Doss S, Matrisian L, Hurd MW, Snyder R, Katz MHG, Wang H, Maitra A, Shen JP, Zhao D. Impact of KRAS Mutations and Co-mutations on Clinical Outcomes in Pancreatic Ductal Adenocarcinoma. Res Sq, 2023. e-Pub 2023. PMID: 37609177.
- Piha-Paul SA, Tseng C, Tran HT, Gao M, Karp DD, Subbiah V, Tsimberidou AM, Kawedia JD, Fu S, Pant S, Yap TA, Morris VK, Kee BK, Blum Murphy M, Lim J, Meric-Bernstam F. A phase I trial of the pan-ERBB inhibitor neratinib combined with the MEK inhibitor trametinib in patients with advanced cancer with EGFR mutation/amplification, HER2 mutation/amplification, HER3/4 mutation or KRAS mutation. Cancer Chemother Pharmacol 92(2):107-118, 2023. e-Pub 2023. PMID: 37314501.
- Ngo-Huang AT, Parker NH, Xiao L, Schadler KL, Petzel MQB, Prakash LR, Kim MP, Tzeng CD, Lee JE, Ikoma N, Wolff RA, Javle MM, Koay EJ, Pant SD, Folloder JP, Wang X, Cotto AM, Ju YR, Garg N, Wang H, Bruera ED, Basen-Engquist KM, Katz MHG. Effects of a Pragmatic Home-based Exercise Program Concurrent with Neoadjuvant Therapy on Physical Function of Patients with Pancreatic Cancer: The Pancfit Randomized Clinical Trial. Ann Surg 278(1):22-30, 2023. e-Pub 2023. PMID: 37026453.
- Harding JJ, Fan J, Oh DY, Choi HJ, Kim JW, Chang HM, Bao L, Sun HC, Macarulla T, Xie F, Metges JP, Ying J, Bridgewater J, Lee MA, Tejani MA, Chen EY, Kim DU, Wasan H, Ducreux M, Bao Y, Boyken L, Ma J, Garfin P, Pant S, group HS. Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01): a multicentre, single-arm, phase 2b study. Lancet Oncol 24(7):772-782, 2023. e-Pub 2023. PMID: 37276871.
- Pant S, Hamilton E, Ulahannan SV, Strauss JF, Braiteh FS, Huang M, Liaw DCH. Phase 1b study of pan-AKT inhibitor vevorisertib alone or with paclitaxel or fulvestrant in PIK3CA/AKT/PTEN-mutated advanced solid tumors. Cancer 129(12):1919-1929, 2023. e-Pub 2023. PMID: 36970876.
- Subbiah V, Pant S. Translating immuno-onco-microbiome-based therapeutics: precision bugs for immune checkpoint drugs!. Ann Oncol 34(6):503-506, 2023. e-Pub 2023. PMID: 37295905.
- DiPeri TP, Kong K, Varadarajan K, Karp DD, Ajani JA, Pant S, Press MF, Piha-Paul SA, Dumbrava EE, Meric-Bernstam F. Discordance of HER2 Expression and/or Amplification on Repeat Testing. Mol Cancer Ther. e-Pub 2023. PMID: 37339271.
- Carmagnani Pestana R, Moyers JT, Roszik J, Sen S, Hong DS, Naing A, Herzog CE, Fu S, Piha-Paul SA, Rodon J, Yap TA, Karp DD, Tsimberidou AM, Pant S, Zarzour MA, Ratan R, Ravi V, Benjamin RS, Lazar AJ, Wang WL, Daw N, Gill JB, Harrison DJ, Lewis VO, Roland CL, Patel SR, Livingston JA, Somaiah N, Ludwig JA, Conley AP, Hamerschlak N, Gorlick R, Meric-Bernstam F, Subbiah V. Impact of Biomarker-Matched Therapies on Outcomes in Patients with Sarcoma Enrolled in Early-Phase Clinical Trials (SAMBA 101). Clin Cancer Res 29(9):1708-1718, 2023. e-Pub 2023. PMID: 37058010.
- Janku F, Javle MM, Sen S, Pant S, Bramwell LG, Subbiah V, Way T, Wages DS, Wheeler CA, Suzuki T, Saeki K, Subach RA, Madden T, Maier G, Johansen MJ, Cheung K, Falchook GS. A phase 1/2a safety, pharmacokinetics, and efficacy study of the novel nucleoside analog FF-10502-01 for the treatment of advanced solid tumors. Cancer 129(10):1537-1546, 2023. e-Pub 2023. PMID: 36882377.
- Gencel-Augusto J, Su X, Qi Y, Whitley EM, Pant V, Xiong S, Shah V, Lin J, Perez E, Fiorotto ML, Mahmud I, Jain AK, Lorenzi PL, Navin NE, Richie ER, Lozano G. Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. Cancer Discov 13(5):1230-1249, 2023. e-Pub 2023. PMID: 37067911.
- Newhook TE, Vreeland TJ, Griffin JF, Tidwell RSS, Prakash LR, Koay EJ, Ludmir EB, Smaglo BG, Pant S, Overman M, Wolff RA, Ikoma N, Maxwell J, Kim MP, Lee JE, Katz MHG, Tzeng CD. Prognosis Associated With CA19-9 Response Dynamics and Normalization During Neoadjuvant Therapy in Resected Pancreatic Adenocarcinoma. Ann Surg 277(3):484-490, 2023. e-Pub 2023. PMID: 36649067.
- Son J, Lin HY, Fu S, Biter AB, Dumbrava EE, Karp DD, Naing A, Pant S, Piha-Paul SA, Rodon J, Subbiah V, Tsimberidou AM, Yap TA, Frumovitz MM, Jazaeri AA, Ramirez PT, Westin SN, Yuan Y, Meric-Bernstam F, Hong DS. Predictors of Oncologic Outcome in Patients Receiving Phase I Investigational Therapy for Recurrent or Metastatic Cervical Cancer. J Immunother Precis Oncol 6(1):10-18, 2023. e-Pub 2023. PMID: 36751659.
- Pant S, Dragovich T, Lieu C, Jimeno A, Kundranda M, Menter D, Tchaparian E, Chen YC, Kopetz S. Phase 1 study of the safety, pharmacokinetics, and preliminary efficacy of CA102N as monotherapy and in combination with trifluridine-tipiracil in patients with locally advanced or metastatic solid tumors. Invest New Drugs 41(1):25-34, 2023. e-Pub 2023. PMID: 36331676.
- Westin SN, Fu S, Tsimberidou A, Piha-Paul S, Akhmedzhanov F, Yilmaz B, McQuinn L, Brink AL, Gong J, Leung CH, Lin H, Hong DS, Pant S, Carter B, Jazaeri A, Gershenson D, Sood AK, Coleman RL, Shah J, Meric-Bernstam F, Naing A. Selinexor in combination with weekly paclitaxel in patients with metastatic solid tumors: Results of an open label, single-center, multi-arm phase 1b study with expansion phase in ovarian cancer. Gynecol Oncol 168:76-82, 2023. e-Pub 2023. PMID: 36423446.
- Yap TA, Daver N, Mahendra M, Zhang J, Kamiya-Matsuoka C, Meric-Bernstam F, Kantarjian HM, Ravandi F, Collins ME, Francesco MED, Dumbrava EE, Fu S, Gao S, Gay JP, Gera S, Han J, Hong DS, Jabbour EJ, Ju Z, Karp DD, Lodi A, Molina JR, Baran N, Naing A, Ohanian M, Pant S, Pemmaraju N, Bose P, Piha-Paul SA, Rodon J, Salguero C, Sasaki K, Singh AK, Subbiah V, Tsimberidou AM, Xu QA, Yilmaz M, Zhang Q, Li Y, Bristow CA, Bhattacharjee MB, Tiziani S, Heffernan TP, Vellano CP, Jones P, Heijnen CJ, Kavelaars A, Marszalek JR, Konopleva M. Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nat Med 29(1):115-126, 2023. e-Pub 2023. PMID: 36658425.
- Meric-Bernstam F, Beeram M, Hamilton E, Oh DY, Hanna DL, Kang YK, Elimova E, Chaves J, Goodwin R, Lee J, Nabell L, Rha SY, Mayordomo J, El-Khoueiry A, Pant S, Raghav K, Kim JW, Patnaik A, Gray T, Davies R, Ozog MA, Woolery J, Lee KW. Zanidatamab, a novel bispecific antibody, for the treatment of locally advanced or metastatic HER2-expressing or HER2-amplified cancers: a phase 1, dose-escalation and expansion study. Lancet Oncol 23(12):1558-1570, 2022. e-Pub 2022. PMID: 36400106.
- Kang Y, Deng J, Ling J, Li X, Chiang YJ, Koay EJ, Wang H, Burks JK, Chiao PJ, Hurd MW, Bhutani MS, Lee JH, Weston BR, Maitra A, Ikoma N, Tzeng CD, Lee JE, DePinho RA, Wolff RA, Pant S, McAllister F, Katz MH, Fleming JB, Kim MP. 3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma. J Clin Invest 132(24), 2022. e-Pub 2022. PMID: 36282600.
- Koay EJ, Zaid M, Aliru M, Bagereka P, Van Wieren A, Rodriguez MJ, Jacobson G, Wolff RA, Overman M, Varadhachary G, Pant S, Wang H, Tzeng CW, Ikoma N, Kim M, Lee JE, Katz MH, Tamm E, Bhosale P, Taniguchi CM, Holliday EB, Smith GL, Ludmir EB, Minsky BD, Crane CH, Koong AC, Das P, Wang X, Javle M, Krishnan S. Nab-Paclitaxel, Capecitabine, and Radiation Therapy Following Induction Chemotherapy in Treating Patients with Locally Advanced and Borderline Resectable Pancreatic Cancer: Phase I Trial and Imaging-based Biomarker Validation. Int J Radiat Oncol Biol Phys 114(3):444-453, 2022. e-Pub 2022. PMID: 35863672.
- Ngoi, NY, Pilie, PG, Piha-Paul, SA, Dumbrava, EE, Fu, S, Hong, DS, Karp, DD, Naing, A, Pant, S, Rodon Ahnert, J, Subbiah, V, Tsimberidou, AM, Salguero, C, Brown, CV, Hoadley, WE, Johnson, A, Yuan, Y, Westin, SN, Meric-Bernstam, F, Yap, TA. DNA Damage Response (DDR) Basket of Baskets (D-BOB) Trial. European Journal of Cancer 174:S10, 2022. e-Pub 2022.
- Yap, TA, Ngoi, NY, Dumbrava, EE, Karp, DD, Rodon Ahnert, J, Fu, S, Hong, DS, Naing, A, Pant, S, Piha-Paul, SA, Subbiah, V, Tsimberidou, AM, Dufner, D, Rhudy, J, Gore, SD, Ivy, SP, Yuan, Y, Westin, SN, Mills, GB, Meric-Bernstam, F. NCI10329. European Journal of Cancer 174:S7, 2022. e-Pub 2022.
- Schalck A, Sakellariou-Thompson D, Forget MA, Sei E, Hughes TG, Reuben A, Bai S, Hu M, Kumar T, Hurd MW, Katz MHG, Tzeng CD, Pant S, Javle M, Fogelman DR, Maitra A, Haymaker CL, Kim MP, Navin NE, Bernatchez C. Single cell sequencing reveals trajectory of tumor-infiltrating lymphocyte states in pancreatic cancer. Cancer Discov 12(10):2330-2349, 2022. e-Pub 2022. PMID: 35849783.
- Massard C, Cassier PA, Azaro A, Anderson B, Yuen E, Yu D, Oakley G, Benhadji KA, Pant S. A phase 1b study of crenigacestat (LY3039478) in combination with gemcitabine and cisplatin or gemcitabine and carboplatin in patients with advanced or metastatic solid tumors. Cancer Chemother Pharmacol 90(4):335-344, 2022. e-Pub 2022. PMID: 36030462.
- Bauer T, Cho BC, Heist R, Bazhenova L, Werner T, Goel S, Kim DW, Adkins D, Carvajal RD, Alva A, Eaton K, Wang J, Liu Y, Yan X, Christensen J, Neuteboom S, Chao R, Pant S. First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors. Invest New Drugs 40(5):990-1000, 2022. e-Pub 2022. PMID: 35767205.
- Pant S, Thomas S, Loganathan S, Valapa RB. 3D bioprinted poly(lactic acid)/mesoporous bioactive glass based biomimetic scaffold with rapid apatite crystallization and in-vitro Cytocompatability for bone tissue engineering. Int J Biol Macromol 217:979-997, 2022. e-Pub 2022. PMID: 35908677.
- Mendoza TR, Hong DS, Peterson CB, Stephen B, Dumbrava E, Pant S, Tsimberidou AM, Yap TA, Sheshadri A, Altan M, George G, Castillo L, Rodriguez E, Gong J, Subbiah V, Janku F, Fu S, Piha-Paul SA, Ahnert JR, Karp DD, Cleeland C, Meric-Bernstam F, Naing A. Patient-reported symptom burden in patients with rare cancers receiving pembrolizumab in a phase II Clinical Trial. Sci Rep 12(1):14367, 2022. e-Pub 2022. PMID: 35999229.
- Gouda MA, Huang HJ, Piha-Paul SA, Call SG, Karp DD, Fu S, Naing A, Subbiah V, Pant S, Dustin DJ, Tsimberidou AM, Hong DS, Rodon J, Meric-Bernstam F, Janku F. Longitudinal Monitoring of Circulating Tumor DNA to Predict Treatment Outcomes in Advanced Cancers. JCO Precis Oncol 6:e2100512, 2022. e-Pub 2022. PMID: 35834760.
- Lee S, Shroff RT, Makawita S, Xiao L, Danner De Armas A, Bhosale P, Reddy K, Shalaby A, Raghav K, Pant S, Wolff RA, Javle M. Phase II Study of Ramucirumab in Advanced Biliary Tract Cancer Previously Treated By Gemcitabine-Based Chemotherapy. Clin Cancer Res 28(11):2229-2236, 2022. e-Pub 2022. PMID: 35312753.
- Chan SL, Schuler M, Kang YK, Yen CJ, Edeline J, Choo SP, Lin CC, Okusaka T, Weiss KH, Macarulla T, Cattan S, Blanc JF, Lee KH, Maur M, Pant S, Kudo M, Assenat E, Zhu AX, Yau T, Lim HY, Bruix J, Geier A, Guillén-Ponce C, Fasolo A, Finn RS, Fan J, Vogel A, Qin S, Riester M, Katsanou V, Chaudhari M, Kakizume T, Gu Y, Porta DG, Myers A, Delord JP. A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors. J Exp Clin Cancer Res 41(1):189, 2022. e-Pub 2022. PMID: 35655320.
- Thein KZ, Piha-Paul SA, Tsimberidou A, Karp DD, Janku F, Zarifa A, Shah J, Milton DR, Bean S, McQuinn L, Gong J, Colen R, Carter BW, Subbiah V, Ogbonna DC, Pant S, Meric-Bernstam F, Naing A. Correction to: Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study. Invest New Drugs 40(2):461, 2022. e-Pub 2022. PMID: 34705134.
- Cazacu IM, Pant S, Bhutani MS. Precision Oncology With Germline and Somatic Sequencing in Pancreatic Cancer: The Time Is Now. Pancreas 51(4):295-296, 2022. e-Pub 2022. PMID: 35775636.
- Panettieri E, Maki H, Kim BJ, Kang HC, Cox V, Vega EA, Mizuno T, Pant S, Javle M, Vauthey JN, Kawaguchi Y. Arterial enhancement pattern predicts survival in patients with resectable and unresectable intrahepatic cholangiocarcinoma. Surg Oncol 40:101696, 2022. e-Pub 2022. PMID: 34995974.
- Alhalabi O, Hahn AW, Msaouel P, Meric-Bernstam F, Wilson N, Naing A, Piha-Paul S, Janku F, Pant S, Yap TA, Hong DS, Fu S, Karp D, Beltran K, Campbell E, Le H, Campbell MT, Shah A, Tannir NM, Siefker-Radtke A, Gao J, Roszik J, Subbiah V. Validation of Prognostic Scores in Patients With Metastatic Urothelial Cancer Enrolling in Phase I Targeted Therapy or Next Generation Immunotherapy Trials. Clin Genitourin Cancer 20(1):e16-e24, 2022. e-Pub 2022. PMID: 34362693.
- Lapin M, Huang HJ, Chagani S, Javle M, Shroff RT, Pant S, Gouda MA, Raina A, Madwani K, Holley VR, Call SG, Dustin DJ, Lanman RB, Meric-Bernstam F, Raymond VM, Kwong LN, Janku F. Monitoring of Dynamic Changes and Clonal Evolution in Circulating Tumor DNA From Patients With IDH-Mutated Cholangiocarcinoma Treated With Isocitrate Dehydrogenase Inhibitors. JCO Precis Oncol 6:e2100197, 2022. e-Pub 2022. PMID: 35171660.
- Douglas JE, Liu S, Ma J, Wolff RA, Pant S, Maitra A, Tamm EP, Bhosale P, Katz MHG, Varadhachary GR, Koay EJ. PIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer. BMC Cancer 22(1):14, 2022. e-Pub 2022. PMID: 34980020.
- Zucali PA, Lin CC, Carthon BC, Bauer TM, Tucci M, Italiano A, Iacovelli R, Su WC, Massard C, Saleh M, Daniele G, Greystoke A, Gutierrez M, Pant S, Shen YC, Perrino M, Meng R, Abbadessa G, Lee H, Dong Y, Chiron M, Wang R, Loumagne L, Lépine L, de Bono J. Targeting CD38 and PD-1 with isatuximab plus cemiplimab in patients with advanced solid malignancies: results from a phase I/II open-label, multicenter study. J Immunother Cancer 10(1), 2022. e-Pub 2022. PMID: 35058326.
- Coleman N, Subbiah V, Pant S, Patel K, Roy-Chowdhuri S, Yedururi S, Johnson A, Yap TA, Rodon J, Shaw K, Meric-Bernstam F. Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition. NPJ Precis Oncol 5(1):99, 2021. e-Pub 2021. PMID: 34853384.
- Pant S, Moyers JT, Naing A. Letter to the editor from Pant et al. J Immunother Cancer 9(11):e003991, 2021. e-Pub 2021. PMID: 34725215.
- Thein KZ, Piha-Paul SA, Tsimberidou A, Karp DD, Janku F, Zarifa A, Shah J, Milton DR, Bean S, McQuinn L, Gong J, Colen R, Carter BW, Subbiah V, Ogbonna DC, Pant S, Meric-Bernstam F, Naing A. Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study. Invest New Drugs 39(5):1357-1365, 2021. e-Pub 2021. PMID: 33909232.
- Rogers JE, Mizrahi JD, Nogueras Gonzalez GM, Surana R, Shroff RT, Wolff R, Varadhachary GR, Javle MM, Overman M, Raghav K, Pant S. Outcomes of patients with metastatic pancreatic cancer who progress on first restaging imaging. J Gastrointest Oncol 12(5):2268-2274, 2021. e-Pub 2021. PMID: 34790391.
- Pant S. Regarding HER2-Amplified Biliary Tract Cancer. Oncologist 26(9):e1664, 2021. e-Pub 2021. PMID: 34156737.
- Moore KN, Hong DS, Patel MR, Pant S, Ulahannan SV, Jones S, Meric-Bernstam F, Wang JS, Aljumaily R, Hamilton EP, Wittchen ES, Wang X, Lin AB, Bendell JC. A Phase 1b Trial of Prexasertib in Combination with Standard-of-Care Agents in Advanced or Metastatic Cancer. Target Oncol 16(5):569-589, 2021. e-Pub 2021. PMID: 34559360.
- Ferrarotto R, Sousa LG, Qing Y, Kaya D, Stephen B, Jain D, Bell D, Pant S, Tsimberidou AM, Janku F, Blumenschein G, Glisson BS, Ahnert JR, Piha-Paul SA, Lee JJ, Wong MK, Lu C, Meric-Bernstam F, Naing A. Pembrolizumab in Patients with Refractory Cutaneous Squamous Cell Carcinoma: A Phase II Trial. Adv Ther 38(8):4581-4591, 2021. e-Pub 2021. PMID: 34241781.
- Azaro A, Massard C, Tap WD, Cassier PA, Merchan J, Italiano A, Anderson B, Yuen E, Yu D, Oakley G, Benhadji KA, Pant S. A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors. Invest New Drugs 39(4):1089-1098, 2021. e-Pub 2021. PMID: 33686452.
- Mohindroo C, Hasanov M, Rogers JE, Dong W, Prakash LR, Baydogan S, Mizrahi JD, Overman MJ, Varadhachary GR, Wolff RA, Javle MM, Fogelman DR, Lotze MT, Kim MP, Katz MHG, Pant S, Tzeng CD, McAllister F. Antibiotic use influences outcomes in advanced pancreatic adenocarcinoma patients. Cancer Med 10(15):5041-5050, 2021. e-Pub 2021. PMID: 34250759.
- Huey RW, George GC, Phillips P, White R, Fu S, Janku F, Karp DD, Naing A, Piha-Paul S, Subbiah V, Tsimberidou AM, Pant S, Yap TA, Rodon J, Meric-Bernstam F, Shih YT, Hong DS. Patient-Reported Out-of-Pocket Costs and Financial Toxicity During Early-Phase Oncology Clinical Trials. Oncologist 26(7):588-596, 2021. e-Pub 2021. PMID: 33783054.
- Hegde A, Jayaprakash P, Couillault CA, Piha-Paul S, Karp D, Rodon J, Pant S, Fu S, Dumbrava EE, Yap TA, Subbiah V, Bhosale P, Coarfa C, Higgins JP, Williams ET, Wilson TF, Lim J, Meric-Bernstam F, Sumner E, Zain H, Nguyen D, Nguyen LM, Rajapakshe K, Curran MA, Hong DS. A Phase I Dose Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies. Clin Cancer Res 27(11):3050-3060, 2021. e-Pub 2021. PMID: 33771853.
- Xu M, Tapia C, Hajjar J, Sabir S, Colen R, Nagarajan P, Aung PP, Gong J, Rodon J, Fu S, Stephen B, Roy-Chowdhuri S, Le H, Yang V, Zarifa A, Abdelsalam ME, Jhingran A, Javle M, Pant S, Carter B, Milton DR, Sun R, Karp DD, Koay EJ, Yang Y, Wistuba II, Hwu P, Meric-Bernstam F, Naing A. Implementation of a Novel Web-Based Lesion Selection Tool to Improve Acquisition of Tumor Biopsy Specimens. J Immunother Precis Oncol 4(2):45-52, 2021. e-Pub 2021. PMID: 35663531.
- Perri G, Prakash L, Wang H, Bhosale P, Varadhachary GR, Wolff R, Fogelman D, Overman M, Pant S, Javle M, Koay E, Herman J, Kim M, Ikoma N, Tzeng CW, Lee JE, Katz MHG. Radiographic and Serologic Predictors of Pathologic Major Response to Preoperative Therapy for Pancreatic Cancer. Ann Surg 273(4):806-813, 2021. e-Pub 2021. PMID: 31274655.
- Falchook G, Infante J, Arkenau HT, Patel MR, Dean E, Borazanci E, Brenner A, Cook N, Lopez J, Pant S, Frankel A, Schmid P, Moore K, McCulloch W, Grimmer K, O'Farrell M, Kemble G, Burris H. First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors. EClinicalMedicine 34:100797, 2021. e-Pub 2021. PMID: 33870151.
- Ballhausen A, Wheler JJ, Karp DD, Piha-Paul SA, Fu S, Pant S, Tsimberidou AM, Hong DS, Subbiah V, Holley VR, Huang HJ, Brewster AM, Koenig KB, Ibrahim NK, Meric-Bernstam F, Janku F. Phase I Study of Everolimus, Letrozole, and Trastuzumab in Patients with Hormone Receptor-positive Metastatic Breast Cancer or Other Solid Tumors. Clin Cancer Res 27(5):1247-1255, 2021. e-Pub 2021. PMID: 33115815.
- Lee MS, Pant S. Personalizing Medicine With Germline and Somatic Sequencing in Advanced Pancreatic Cancer: Current Treatments and Novel Opportunities. Am Soc Clin Oncol Educ Book 41:1-13, 2021. e-Pub 2021. PMID: 33929876.
- Alhalabi O, Hahn AW, Msaouel P, Andreev-Drakhlin AY, Meric-Bernstam F, Naing A, Piha-Paul S, Filip J, Pant S, Yap TA, Hong DS, Fu S, Karp D, Campbell E, Le H, Campbell MT, Shah AY, Tannir NM, Siefker-Radtke AO, Gao J, Roszik J, Subbiah V. Molecular Profiling of Metastatic Bladder Cancer Early-Phase Clinical Trial Participants Predicts Patient Outcomes. Mol Cancer Res 19(3):395-402, 2021. e-Pub 2021. PMID: 33323389.
- Hecht JR, Papadopoulos KP, Falchook GS, Patel MR, Infante JR, Aljumaily R, Wong DJ, Autio KA, Wainberg ZA, Bauer TM, Javle M, Pant S, Bendell J, Hung A, Ratti N, VanVlasselaer P, Verma R, Leveque J, Rao S, Oft M, Naing A. Immunologic and tumor responses of pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in pancreatic ductal adenocarcinoma (PDAC). Invest New Drugs 39(1):182-192, 2021. e-Pub 2021. PMID: 32910338.
- Henry JT, Coker O, Chowdhury S, Shen JP, Morris VK, Dasari A, Raghav K, Nusrat M, Kee B, Parseghian C, Pant S, Jeyakumar N, Zhu L, Nishioka Y, Fogelman D, Wolff RA, Hong D, Overman MJ, Vauthey J, Kopetz S, Johnson B. Comprehensive Clinical and Molecular Characterization of KRAS G12C-Mutant Colorectal Cancer. JCO Precis Oncol 5:613-621, 2021. e-Pub 2021. PMID: 34250391.
- Surana R, Pant S. Immunotherapy in Gastrointestinal Malignancies. Adv Exp Med Biol 1342:259-272, 2021. e-Pub 2021. PMID: 34972968.
- Abdel-Wahab R, Yap TA, Madison R, Pant S, Cooke M, Wang K, Zhao H, Bekaii-Saab T, Karatas E, Kwong LN, Meric-Bernstam F, Borad M, Javle M. Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer. Sci Rep 10(1):22087, 2020. e-Pub 2020. PMID: 33328484.
- Subbiah V, Erwin W, Mawlawi O, McCoy A, Wages D, Wheeler C, Gonzalez-Lepera C, Liu H, Macapinlac H, Meric-Bernstam F, Hong DS, Pant S, Le D, Santos E, Gonzalez J, Roszik J, Suzuki T, Subach RA, Madden T, Johansen M, Nomura F, Satoh H, Matsuura T, Kajita M, Nakamura E, Funase Y, Matsushima S, Ravizzini G. Phase I Study of P-cadherin-targeted Radioimmunotherapy with 90Y-FF-21101 Monoclonal Antibody in Solid Tumors. Clin Cancer Res 26(22):5830-5842, 2020. e-Pub 2020. PMID: 32816889.
- Saleh M, Cassier PA, Eberst L, Naik G, Morris VK, Pant S, Terret C, Gao L, Long A, Mao H, McNeely S, Wagner EK, Carlesi RM, Fu S. Phase I Study of Ramucirumab Plus Merestinib in Previously Treated Metastatic Colorectal Cancer: Safety, Preliminary Efficacy, and Pharmacokinetic Findings. Oncologist 25(11):e1628-e1639, 2020. e-Pub 2020. PMID: 32537847.
- Hahn AW, Alhalabi O, Msaouel P, Meric-Bernstam F, Naing A, Jonasch E, Piha-Paul S, Hong D, Pant S, Yap T, Campbell E, Le H, Tannir NM, Roszik J, Subbiah V. Validation of prognostic scoring systems for patients with metastatic renal cell carcinoma enrolled in phase I clinical trials. ESMO Open 5(6):e001073, 2020. e-Pub 2020. PMID: 33229506.
- Voss MH, Gordon MS, Mita M, Rini B, Makker V, Macarulla T, Smith DC, Cervantes A, Puzanov I, Pili R, Wang D, Jalal S, Pant S, Patel MR, Neuwirth RL, Enke A, Shou Y, Sedarati F, Faller DV, Burris HA. Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer. Br J Cancer 123(11):1590-1598, 2020. e-Pub 2020. PMID: 32913286.
- Pant S, Lee MS. Barriers to Pancreatic Clinical Trials Enrollment. Oncology (Williston Park) 34(10), 2020. e-Pub 2020. PMID: 33090379.
- Perri G, Prakash L, Malleo G, Caravati A, Varadhachary GR, Fogelman D, Pant S, Koay EJ, Herman J, Maggino L, Milella M, Kim M, Ikoma N, Tzeng CW, Salvia R, Lee JE, Bassi C, Katz MHG. The Sequential Radiographic Effects of Preoperative Chemotherapy and (Chemo)Radiation on Tumor Anatomy in Patients with Localized Pancreatic Cancer. Ann Surg Oncol 27(10):3939-3947, 2020. e-Pub 2020. PMID: 32266574.
- Mendoza T, Sheshadri A, Altan M, Hess K, George G, Stephen B, Castillo L, Rodriguez E, Gong J, Peterson C, Rodon Ahnert J, Fu S, Piha-Paul SA, Pant S, Dumbrava E, Yap TA, Janku F, Tsimberidou AM, Subbiah V, Karp DD, Zarifa A, McQuinn LM, Cleeland C, Hong DS, Naing A. Evaluating the psychometric properties of the Immunotherapy module of the MD Anderson Symptom Inventory. J Immunother Cancer 8(2), 2020. e-Pub 2020. PMID: 33097611.
- Perri G, Prakash L, Qiao W, Varadhachary GR, Wolff R, Fogelman D, Overman M, Pant S, Javle M, Koay EJ, Herman J, Kim M, Ikoma N, Tzeng CW, Lee JE, Katz MHG. Response and Survival Associated With First-line FOLFIRINOX vs Gemcitabine and nab-Paclitaxel Chemotherapy for Localized Pancreatic Ductal Adenocarcinoma. JAMA Surg 155(9):832-839, 2020. e-Pub 2020. PMID: 32667641.
- Sohal DPS, Kennedy EB, Cinar P, Conroy T, Copur MS, Crane CH, Garrido-Laguna I, Lau MW, Johnson T, Krishnamurthi S, Moravek C, O'Reilly EM, Philip PA, Pant S, Shah MA, Sahai V, Uronis HE, Zaidi N, Laheru D. Metastatic Pancreatic Cancer: ASCO Guideline Update. J Clin Oncol:JCO2001364. e-Pub 2020. PMID: 32755482.
- Rogers JE, Mizrahi JD, Xiao L, Mohindroo C, Shroff RT, Wolff R, Varadhachary GR, Javle MM, Overman M, Fogelman DR, Raghav KPS, Pant S, McAllister F. Modified gemcitabine plus nab-paclitaxel regimen in advanced pancreatic ductal adenocarcinoma. Cancer Med 9(15):5406-5415, 2020. e-Pub 2020. PMID: 32519420.
- Perri G, Prakash L, Qiao W, Varadhachary GR, Wolff R, Fogelman D, Overman M, Pant S, Javle M, Koay EJ, Herman J, Kim M, Ikoma N, Tzeng CW, Lee JE, Katz MHG. Postoperative Chemotherapy Benefits Patients Who Received Preoperative Therapy and Pancreatectomy for Pancreatic Adenocarcinoma. Ann Surg 271(6):996-1002, 2020. e-Pub 2020. PMID: 31895709.
- Mizrahi JD, Rogers JE, Hess KR, Wolff RA, Varadhachary GR, Javle MM, Shroff RT, Ho L, Fogelman DR, Raghav KPS, Overman MJ, Pant S. Modified FOLFIRINOX in pancreatic cancer patients Age 75 or older. Pancreatology 20(3):501-504, 2020. e-Pub 2020. PMID: 31932214.
- Naing A, Meric-Bernstam F, Stephen B, Karp DD, Hajjar J, Rodon Ahnert J, Piha-Paul SA, Colen RR, Jimenez C, Raghav KP, Ferrarotto R, Tu SM, Campbell M, Wang L, Sabir SH, Tapia C, Bernatchez C, Frumovitz M, Tannir N, Ravi V, Khan S, Painter JM, Abonofal A, Gong J, Alshawa A, McQuinn LM, Xu M, Ahmed S, Subbiah V, Hong DS, Pant S, Yap TA, Tsimberidou AM, Dumbrava EEI, Janku F, Fu S, Simon RM, Hess KR, Varadhachary GR, Habra MA. Phase 2 study of pembrolizumab in patients with advanced rare cancers. J Immunother Cancer 8(1), 2020. e-Pub 2020. PMID: 32188704.
- Rogers JE, Mizrahi JD, Shroff RT, Nelson DA, Tu J, Javle MM, Wolff RA, Pant S. Dose-modified gemcitabine plus nab-paclitaxel front-line in advanced pancreatic ductal adenocarcinoma with baseline hyperbilirubinemia. J Gastrointest Oncol 11(1):55-60, 2020. e-Pub 2020. PMID: 32175105.
- Mizrahi J, Pant S. Immunotherapy in Gastrointestinal Malignancies. Adv Exp Med Biol 1244:93-106, 2020. e-Pub 2020. PMID: 32301012.
- Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S, Lazar AJ, Pant S, Meric-Bernstam F. Overview of the TREC 2019 Precision Medicine Track. Text Retr Conf 1250, 2019. e-Pub 2019. PMID: 34849512.
- Naing A, Wong DJ, Infante JR, Korn WM, Aljumaily R, Papadopoulos KP, Autio KA, Pant S, Bauer TM, Drakaki A, Daver NG, Hung A, Ratti N, McCauley S, Van Vlasselaer P, Verma R, Ferry D, Oft M, Diab A, Garon EB, Tannir NM. Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial. Lancet Oncol 20(11):1544-1555, 2019. e-Pub 2019. PMID: 31563517.
- Maymani H, Hess K, Groisberg R, Hong DS, Naing A, Piha-Paul S, Janku F, Fu S, Tsimberidou AM, Pant S, Karp D, Liu S, Sun M, Heymach J, Simon G, Meric-Bernstam F, Subbiah V. Corrigendum to "Predicting outcomes in patients with advanced non-small cell lung cancer enrolled in early phase immunotherapy trials" [Lung Cancer 120 (June) (2018) 137-141]. Lung Cancer 136:158, 2019. e-Pub 2019. PMID: 31445783.
- Pant S, Maitra A, Yap TA. PARP inhibition - opportunities in pancreatic cancer. Nat Rev Clin Oncol 16(10):595-596, 2019. e-Pub 2019. PMID: 31332344.
- Habra MA, Stephen B, Campbell M, Hess K, Tapia C, Xu M, Rodon Ahnert J, Jimenez C, Lee JE, Perrier ND, Boraddus RR, Pant S, Subbiah V, Hong DS, Zarifa A, Fu S, Karp DD, Meric-Bernstam F, Naing A. Phase II clinical trial of pembrolizumab efficacy and safety in advanced adrenocortical carcinoma. J Immunother Cancer 7(1):253, 2019. e-Pub 2019. PMID: 31533818.
- Bhutani MS, Cazacu IM, Luzuriaga Chavez AA, Singh BS, Wong FCL, Erwin WD, Tamm EP, Mathew GG, Le DB, Koay EJ, Taniguchi CM, Minsky BD, Pant S, Tzeng CD, Koong AC, Varadhachary GR, Katz MHG, Wolff RA, Fogelman DR, Herman JM. Novel EUS-guided brachytherapy treatment of pancreatic cancer with phosphorus-32 microparticles: first United States experience. VideoGIE 4(5):223-225, 2019. e-Pub 2019. PMID: 31065616.
- George GC, Iwuanyanwu EC, Buford AS, Piha-Paul SA, Subbiah V, Fu S, Karp DD, Pant S, Hinojosa CO, Hess KR, Cleeland CS, Bernstam EV, Meric-Bernstam F, Hong DS. Cancer-Related Internet Use and Its Association With Patient Decision Making and Trust in Physicians Among Patients in an Early Drug Development Clinic: A Questionnaire-Based Cross-Sectional Observational Study. J Med Internet Res 21(3):e10348, 2019. e-Pub 2019. PMID: 30869638.
- Dumbrava EEI, Balaji K, Raghav K, Hess K, Javle M, Blum-Murphy M, Ajani J, Kopetz S, Broaddus R, Routbort M, Demirhan M, Zheng X, Pant S, Tsimberidou AM, Subbiah V, Hong DS, Rodon J, Shaw KM, Piha-Paul SA, Meric-Bernstam F. Targeting ERBB2 (HER2) Amplification Identified by Next-Generation Sequencing in Patients With Advanced or Metastatic Solid Tumors Beyond Conventional Indications. JCO Precis Oncol 3, 2019. e-Pub 2019. PMID: 32923865.
- Johnson B, Loree JM, Jacome AA, Mendis S, Syed M, Morris Ii VK, Parseghian CM, Dasari A, Pant S, Raymond VM, Vilar E, Overman M, Kee B, Eng C, Raghav K, Kopetz S. Atypical, Non-V600 BRAF Mutations as a Potential Mechanism of Resistance to EGFR Inhibition in Metastatic Colorectal Cancer. JCO Precis Oncol 3, 2019. e-Pub 2019. PMID: 32914034.
- Aghajanian C, Bell-McGuinn KM, Burris HA, Siu LL, Stayner LA, Wheler JJ, Hong DS, Kurkjian C, Pant S, Santiago-Walker A, Gauvin JL, Antal JM, Opalinska JB, Morris SR, Infante JR. A phase I, open-label, two-stage study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the oral AKT inhibitor GSK2141795 in patients with solid tumors. Invest New Drugs 36(6):1016-1025, 2018. e-Pub 2018. PMID: 29611022.
- Naing A, Infante JR, Papadopoulos KP, Chan IH, Shen C, Ratti NP, Rojo B, Autio KA, Wong DJ, Patel MR, Ott PA, Falchook GS, Pant S, Hung A, Pekarek KL, Wu V, Adamow M, McCauley S, Mumm JB, Wong P, Van Vlasselaer P, Leveque J, Tannir NM, Oft M. PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients. Cancer Cell 34(5):775-791.e3, 2018. e-Pub 2018. PMID: 30423297.
- Bendell JC, Varghese AM, Hyman DM, Bauer TM, Pant S, Callies S, Lin J, Martinez R, Wickremsinhe E, Fink A, Wacheck V, Moore KN. A First-in-Human Phase 1 Study of LY3023414, an Oral PI3K/mTOR Dual Inhibitor, in Patients with Advanced Cancer. Clin Cancer Res 24(14):3253-3262, 2018. e-Pub 2018. PMID: 29636360.
- Parseghian CM, Patnana M, Bhosale P, Hess KR, Shih YT, Kim B, Kopetz S, Overman MJ, Varadhachary GR, Javle M, Naing A, Piha-Paul S, Hong D, Le H, Subbiah V, Pant S. Evaluating for Pseudoprogression in Colorectal and Pancreatic Tumors Treated With Immunotherapy. J Immunother 41(6):284-291, 2018. e-Pub 2018. PMID: 29668571.
- Maymani H, Hess K, Groisberg R, Hong DS, Naing A, Piha-Paul S, Janku F, Fu S, Tsimberidou AM, Pant S, Karp D, Liu S, Sun M, Heymach J, Simon G, Meric-Bernstam F, Subbiah V. Predicting outcomes in patients with advanced non-small cell lung cancer enrolled in early phase immunotherapy trials. Lung Cancer 120:137-141, 2018. e-Pub 2018. PMID: 29748008.
- Sen S, Kato S, Agarwal R, Piha-Paul S, Hess K, Karp D, Janku F, Fu S, Naing A, Pant S, Falchook G, Tang C, Wu X, Ye Y, Tsimberidou A, Subbiah V, Kurzrock R, Byers L, Westin S, Lim J, Bean S, Bass A, Nguyen L, Meric-Bernstam F, Hong D. Phase I study of nab-paclitaxel, gemcitabine, and bevacizumab in patients with advanced cancers. Br J Cancer 118(11):1419-1424, 2018. e-Pub 2018. PMID: 29695765.
- Zhou X, Nemunaitis J, Pant S, Bauer TM, Patel M, Sarantopoulos J, Craig Lockhart A, Goodman D, Huebner D, Mould DR, Venkatakrishnan K. Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies. Invest New Drugs 36(2):240-247, 2018. e-Pub 2018. PMID: 28819760.
- Zhou X, Pant S, Nemunaitis J, Craig Lockhart A, Falchook G, Bauer TM, Patel M, Sarantopoulos J, Bargfrede M, Muehler A, Rangachari L, Zhang B, Venkatakrishnan K. Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies. Invest New Drugs 36(2):248-258, 2018. e-Pub 2018. PMID: 28852909.
- Lam M, Pant S, Yap TA. Combination drug development in BRAF mutant colorectal cancer. Oncoscience 5(3-4):51-53, 2018. e-Pub 2018. PMID: 29854866.
- Roberts K, Demner-Fushman D, Voorhees EM, Hersh WR, Bedrick S, Lazar AJ, Pant S. Overview of the TREC 2017 Precision Medicine Track. Text Retr Conf 26, 2017. e-Pub 2017. PMID: 32776021.
- Pant S, Patel M, Kurkjian C, Hemphill B, Flores M, Thompson D, Bendell J. A Phase II Study of the c-Met Inhibitor Tivantinib in Combination with FOLFOX for the Treatment of Patients with Previously Untreated Metastatic Adenocarcinoma of the Distal Esophagus, Gastroesophageal Junction, or Stomach. Cancer Invest 35(7):1-10, 2017. e-Pub 2017. PMID: 28662341.
- Kehl KL, Fullmer CP, Fu S, George GC, Hess KR, Janku F, Karp DD, Kato S, Kizer CK, Kurzrock R, Naing A, Pant S, Piha-Paul SA, Subbiah V, Tsimberidou AM, Hong DS. Insurance Clearance for Early-Phase Oncology Clinical Trials Following the Affordable Care Act. Clin Cancer Res. e-Pub 2017. PMID: 28729355.
- Burris HA, Kurkjian CD, Hart L, Pant S, Murphy PB, Jones SF, Neuwirth R, Patel CG, Zohren F, Infante JR. TAK-228 (formerly MLN0128), an investigational dual TORC1/2 inhibitor plus paclitaxel, with/without trastuzumab, in patients with advanced solid malignancies. Cancer Chemother Pharmacol. e-Pub 2017. PMID: 28601972.
- Pant S, Martin LK, Geyer S, Wei L, Van Loon K, Sommovilla N, Zalupski M, Iyer R, Fogelman D, Ko AH, Bekaii-Saab T. Treatment-related Hypertension as a Pharmacodynamic Biomarker for the Efficacy of Bevacizumab in Advanced Pancreas Cancer: A Pooled Analysis of 4 Prospective Trials of Gemcitabine-based Therapy With Bevacizumab. Am J Clin Oncol 39(6):614-618, 2016. e-Pub 2016. PMID: 25068471.
- Sarantopoulos J, Goel S, Chung V, Munster P, Pant S, Patel MR, Infante J, Tawbi H, Becerra C, Bruce J, Kabbinavar F, Lockhart AC, Tan E, Yang S, Carlson G, Scott JW, Sharma S. Randomized phase 1 crossover study assessing the bioequivalence of capsule and tablet formulations of dovitinib (TKI258) in patients with advanced solid tumors. Cancer Chemother Pharmacol 78(5):921-927, 2016. e-Pub 2016. PMID: 27681579.
- Naing A, Papadopoulos KP, Autio KA, Ott PA, Patel MR, Wong DJ, Falchook GS, Pant S, Whiteside M, Rasco DR, Mumm JB, Chan IH, Bendell JC, Bauer TM, Colen RR, Hong DS, Van Vlasselaer P, Tannir NM, Oft M, Infante JR. Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors. J Clin Oncol 34(29):3562-3569, 2016. e-Pub 2016. PMID: 27528724.
- Wirth LJ, Dakhil S, Kornek G, Axelrod R, Adkins D, Pant S, O'Brien P, Debruyne PR, Oliner KS, Dong J, Murugappan S. PARTNER: An open-label, randomized, phase 2 study of docetaxel/cisplatin chemotherapy with or without panitumumab as first-line treatment for recurrent or metastatic squamous cell carcinoma of the head and neck. Oral Oncol 61:31-40, 2016. e-Pub 2016. PMID: 27688102.
- Noonan AM, Farren MR, Geyer SM, Huang Y, Tahiri S, Ahn D, Mikhail S, Ciombor KK, Pant S, Aparo S, Sexton J, Marshall JL, Mace TA, Wu CS, El-Rayes B, Timmers CD, Zwiebel J, Lesinski GB, Villalona-Calero MA, Bekaii-Saab TS. Randomized Phase II Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma. Mol Ther 24(6):1150-8, 2016. e-Pub 2016. PMID: 27039845.
- Bendell JC, Patel MR, Yoshida K, Seraj J, Weaver R, Lemech C, Todaro TG, Pant S, Arkenau HT. Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors. Cancer Chemother Pharmacol 77(6):1275-83, 2016. e-Pub 2016. PMID: 27151157.
- Pant S, Jones SF, Kurkjian CD, Infante JR, Moore KN, Burris HA, McMeekin DS, Benhadji KA, Patel BK, Frenzel MJ, Kursar JD, Zamek-Gliszczynski MJ, Yuen ES, Chan EM, Bendell JC. A first-in-human phase I study of the oral Notch inhibitor, LY900009, in patients with advanced cancer. Eur J Cancer 56:1-9, 2016. e-Pub 2016. PMID: 26798966.
- Tolaney SM, Beeram M, Beck JT, Conlin AK, Dees EC, Dickler MN, Helsten TL, Conkling PR, Edenfield WJ, Richards DA, Turner PK, Cai N, Chan EM, Pant S, Becerra C, Kalinsky K, Puhalla S, Rexer BN, Burris HA, Goetz MP. A Phase 1b Study of Abemaciclib, an inhibitor of CDK4 and CDK6, in Combination with Endocrine and HER2-targeted Therapies for Patients with Metastatic Breast Cancer. Annals of Oncology 27(6):v552-v587, 2016. e-Pub 2016.
- Phan M, Jones S, Jenkins J, Pant S, Khawandanah M. Pancreatic GIST in a Patient with Limited Stage Small Cell Lung Cancer: A Case Report and Review of Published Cases. Case Rep Oncol Med 2016:9604982, 2016. e-Pub 2016. PMID: 27579203.
- Khawandanah M, Baxley A, Pant S. Recurrent metastatic anal cancer treated with modified paclitaxel, ifosfamide, and cisplatin and third-line mitomycin/cetuximab. J Oncol Pharm Pract 21(3):232-7, 2015. e-Pub 2015. PMID: 24627343.
- Bendell JC, Patel MR, Infante JR, Kurkjian CD, Jones SF, Pant S, Burris HA, Moreno O, Esquibel V, Levin W, Moore KN. Phase 1, open-label, dose escalation, safety, and pharmacokinetics study of ME-344 as a single agent in patients with refractory solid tumors. Cancer 121(7):1056-63, 2015. e-Pub 2015. PMID: 25411085.
- Suttle AB, Grossmann KF, Ouellet D, Richards-Peterson LE, Aktan G, Gordon MS, LoRusso PM, Infante JR, Sharma S, Kendra K, Patel M, Pant S, Arkenau HT, Middleton MR, Blackman SC, Botbyl J, Carson SW. Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib. J Clin Pharmacol 55(4):392-400, 2015. e-Pub 2015. PMID: 25449654.
- Ahmad B, Pierson N, Adnan MM, Phan M, Jenkins J, Pant S, Cherry M, Khawandanah M. Distant skin metastases as primary presentation of gastric cancer. J Community Support Oncol 13(4):156-8, 2015. e-Pub 2015. PMID: 26102608.
- Bendell JC, Jones SF, Hart L, Pant S, Moyhuddin A, Lane CM, Earwood C, Murphy P, Patton J, Penley WC, Thompson D, Infante JR. A Phase I Study of the Hsp90 Inhibitor AUY922 plus Capecitabine for the Treatment of Patients with Advanced Solid Tumors. Cancer Invest 33(10):477-82, 2015. e-Pub 2015. PMID: 26460795.
- Qu D, Johnson J, Chandrakesan P, Weygant N, May R, Aiello N, Rhim A, Zhao L, Zheng W, Lightfoot S, Pant S, Irvan J, Postier R, Hocker J, Hanas JS, Ali N, Sureban SM, An G, Schlosser MJ, Stanger B, Houchen CW. Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells. PLoS One 10(2):e0118933, 2015. e-Pub 2015. PMID: 25723399.
- Li D, Pant S, Ryan DP, Laheru D, Bahary N, Dragovich T, Hosein PJ, Rolfe L, Saif MW, LaValle J, Yu KH, Lowery MA, Allen A, O'Reilly EM. A phase II, open-label, multicenter study to evaluate the antitumor efficacy of CO-1.01 as second-line therapy for gemcitabine-refractory patients with stage IV pancreatic adenocarcinoma and negative tumor hENT1 expression. Pancreatology 14(5):398-402, 2014. e-Pub 2014. PMID: 25278310.
- Pant S, Saleh M, Bendell J, Infante JR, Jones S, Kurkjian CD, Moore KM, Kazakin J, Abbadessa G, Wang Y, Chen Y, Schwartz B, Camacho LH. A phase I dose escalation study of oral c-MET inhibitor tivantinib (ARQ 197) in combination with gemcitabine in patients with solid tumors. Ann Oncol 25(7):1416-21, 2014. e-Pub 2014. PMID: 24737778.
- Pant S, Martin LK, Geyer S, Wei L, Van Loon K, Sommovilla N, Sommovilla N, Zalupski M, Iyer R, Fogelman D, Ko AH, Bekaii-Saab T. Baseline serum albumin is a predictive biomarker for patients with advanced pancreatic cancer treated with bevacizumab: a pooled analysis of 7 prospective trials of gemcitabine-based therapy with or without bevacizumab. Cancer 120(12):1780-6, 2014. e-Pub 2014. PMID: 24633933.
- Pant S, Burris HA, Moore K, Bendell JC, Kurkjian C, Jones SF, Moreno O, Kuhn JG, McMeekin S, Infante JR. A first-in-human dose-escalation study of ME-143, a second generation NADH oxidase inhibitor, in patients with advanced solid tumors. Invest New Drugs 32(1):87-93, 2014. e-Pub 2014. PMID: 23525756.
- Kurkjian N, Kurkjian C, Pant S, Tucker P. Psycho-oncology: a brief history and case study. J Okla State Med Assoc 106(12):471-4, 2013. e-Pub 2013. PMID: 24620412.
- Cherry MA, Bhardwaj H, Hopps S, Srour S, Pant S. Ifosfamide-induced neurotoxicity reversal with continuous veno-venous hemodialysis. A case report. J Oncol Pharm Pract 19(3):261-4, 2013. e-Pub 2013. PMID: 23135805.
- Hopps S, Medina P, Pant S, Webb R, Moorman M, Borders E. Cetuximab hypersensitivity infusion reactions: Incidence and risk factors. J Oncol Pharm Pract 19(3):222-7, 2013. e-Pub 2013. PMID: 23135806.
- Landmann A, Makipour JJ, Morgan A, Postier R, Pant S, Liu C, Anderson J. Image of the month. Extramedullary plasmacytoma. JAMA Surg 148(1):101-2, 2013. e-Pub 2013. PMID: 23324848.
- Alinari L, Pant S, McNamara K, Kalmar JR, Marsh W, Allen CM, Baiocchi RA. Lymphomatoid granulomatosis presenting with gingival involvement in an immune competent elderly male. Head Neck Pathol 6(4):496-501, 2012. e-Pub 2012. PMID: 22711054.
- Lustberg MB, Pant S, Ruppert AS, Shen T, Wei Y, Chen L, Brenner L, Shiels D, Jensen RR, Berger M, Mrozek E, Ramaswamy B, Grever M, Au JL, Wientjes MG, Shapiro CL. Phase I/II trial of non-cytotoxic suramin in combination with weekly paclitaxel in metastatic breast cancer treated with prior taxanes. Cancer Chemother Pharmacol 70(1):49-56, 2012. e-Pub 2012. PMID: 22729159.
- Pant S, Hamadani M, Dodds AJ, Szer J, Crilley PA, Stevenson D, Phillips G, Elder P, Nivison-Smith I, Avalos BR, Penza S, Topolsky D, Sobecks R, Kalaycio M, Bolwell BJ, Copelan EA. Incidence and reasons for late failure after allogeneic haematopoietic cell transplantation following BuCy2 in acute myeloid leukaemia. Br J Haematol 148(4):623-6, 2010. e-Pub 2010. PMID: 19821825.
- Pant S, Chilukuri MP, Ramaswamy B. Docetaxel for the post-surgery treatment of patients with node-positive breast cancer. Ther Clin Risk Manag 4(2):419-24, 2008. e-Pub 2008. PMID: 18728853.
- Pant S, Landon MB, Blumenfeld M, Farrar W, Shapiro CL. Treatment of breast cancer with trastuzumab during pregnancy. J Clin Oncol 26(9):1567-9, 2008. e-Pub 2008. PMID: 18349415.
- Pant S, Ozer H. New agents in the treatment of ovarian cancer. Managed Care Oncology(4):26-28, 2008. e-Pub 2008.
- Pant S, Copelan EA. Hematopoietic stem cell transplantation in multiple myeloma. Biol Blood Marrow Transplant 13(8):877-85, 2007. e-Pub 2007. PMID: 17640590.
- Kamble R, Pant S, Selby GB, Kharfan-Dabaja MA, Sethi S, Kratochvil K, Kohrt N, Ozer H. Microbial contamination of hematopoietic progenitor cell grafts-incidence, clinical outcome, and cost-effectiveness: an analysis of 735 grafts. Transfusion 45(6):874-8, 2005. e-Pub 2005. PMID: 15934984.
Review Articles
- Chang, E, Sherry, AD, Liermann, J, Abdollahi, A, Tzeng, CD, Tang, C, Aguilera, T, Koay, EJ, Das, P, Koong, A, Pant, S, Ludmir, EB. Evolving Paradigms in the Treatment of Oligometastatic Pancreatic Ductal Adenocarcinoma. Journal of Gastrointestinal Cancer 56(1), 2025. e-Pub 2025. PMID: 39827280.
- Pant V, Sun C, Lozano G. Tissue specificity and spatio-temporal dynamics of the p53 transcriptional program. Cell Death Differ 30(4):897-905, 2023. e-Pub 2023. PMID: 36755072.
- Alhalabi O, Groisberg R, Zinner R, Hahn AW, Naing A, Zhang S, Tsimberidou AM, Rodon J, Fu S, Yap TA, Hong DS, Sun M, Jiang Y, Pant S, Shah AY, Zurita A, Tannir NM, Vikram R, Roszik J, Meric-Bernstam F, Subbiah V. Phase I study of sapanisertib with carboplatin and paclitaxel in mTOR pathway altered solid malignancies. NPJ Precis Oncol 7(1):37, 2023. e-Pub 2023. PMID: 37072571.
- Yao S, Meric-Bernstam F, Hong D, Janku F, Naing A, Piha-Paul SA, Tsimberidou AM, Karp D, Subbiah V, Yap TA, Ahnert JR, Pant S, Dumbrava EEI, Wathoo C, Campbell E, Yu L, Yamamura Y, Fu S. Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences. Sci Rep 12(1):8701, 2022. e-Pub 2022. PMID: 35610322.
- Coveler AL, Mizrahi J, Eastman BM, Apisarnthanarax SJ, Dalal S, McNearney T, Pant S, Consortium PP. Pancreas Cancer-Associated Pain Management. Oncologist 26(6):e971-e982, 2021. e-Pub 2021. PMID: 33885205.
- Mehrotra R, Tulsyan S, Hussain S, Mittal B, Singh Saluja S, Singh S, Tanwar P, Khan A, Javle M, Hassan MM, Pant S, De Aretxabala X, Sirohi B, Rajaraman P, Kaur T, Rath GK. Genetic landscape of gallbladder cancer: Global overview. Mutat Res 778:61-71, 2018. e-Pub 2018. PMID: 30454684.
- Pant S, Hubbard J, Martinelli E, Bekaii-Saab T. Clinical update on K-Ras targeted therapy in gastrointestinal cancers. Crit Rev Oncol Hematol 130:78-91, 2018. e-Pub 2018. PMID: 30196915.
- Mohammed A, Janakiram NB, Pant S, Rao CV. Molecular Targeted Intervention for Pancreatic Cancer. Cancers (Basel) 7(3):1499-542, 2015. e-Pub 2015. PMID: 26266422.
- Pant S, Ramaswamy B. Association of major stressors with elevated risk of breast cancer incidence or relapse. Drugs Today (Barc) 45(2):115-26, 2009. e-Pub 2009. PMID: 19343231.
- Pant S, Shapiro CL. Aromatase inhibitor-associated bone loss: clinical considerations. Drugs 68(18):2591-600, 2008. e-Pub 2008. PMID: 19093701.
Other Articles
- Hopps S, Kurkjian C, Pant S A Review of PARP Inhibitors in Clinical Development. Journal of Hematology/Oncology Pharmacy 2(1):18-28, 2012.
- Hopps S, Pant S Update on PARP Inhibitors in Breast Cancer. The Oncology Pharmacist 4(3):22, 2011.
- Charania R, Pant S, Morgal S, Borders E Treatment of Metastatic Colon cancer: A Multidiciplinary Approach. Journal of Multidisciplinary Cancer Care 2(3):18-23, 2009.
- Pant, Ozer H New Agents in the Treatment of Ovarian Cancer. Managed Care Oncology 4:26-28, 2008.
- Pant S, Villalona-Calero M Lung Cancer Highlights of ASCO 2007. Lung Cancer Frontiers(31):5-7, 2007.
- Pant S, Ozer H Managing Hematologic Toxicities, A Peer Viewpoint. Journal of Supportive Oncology 2(1):71-2, 2004.
Editorials
- Saj, F, Wu, YL, Pant, S, Goyal, L. Dual checkpoint inhibition in gallbladder cancer. Cancer 130(17):2904-2906, 2024. PMID: 38873826.
Abstracts
- Pant S, Schuler MH, Iyer G, Doi T, Qin S, Tabernero J, Arnold D, Gutierrez M, Prenen H, Folprecht G, Winter H, Cosman R, Dal Molin GZ, Xia Q, Najmi S, Hammond C, Thomas S, Triantos S, Sweiti H, Loriot Y. Efficacy and safety of erdafitinib in adults with cholangiocarcinoma (CCA) with prespecified fibroblast growth factor receptor alterations (FGFRalt) in the phase 2 open-label, single-arm RAGNAR trial: Expansion cohort results. ASCO 2023 41(4s), 2023. e-Pub 2023.
- Wainberg ZA, Melisi D, Macarulla T, Pazo-Cid R, Chandana SR, La Fouchardiere CD, Dean AP, Kiss I, Lee W, Goetze TO, Cutsem EV, Paulson AS, Bekaii-Saab TS, Pant S, Hubner R, Xiao Z, Chen H, Benzaghou F, O'Reilly EM. NAPOLI-3: A randomized, open-label phase 3 study of liposomal irinotecan + 5-fluorouracil/leucovorin + oxaliplatin (NALIRIFOX) versus nab-paclitaxel + gemcitabine in treatment-naïve patients with metastatic pancreatic ductal adenocarcinoma (mPDAC). J Clin Oncol 41(4s), 2023. e-Pub 2023.
- Pant S, Fan J, Oh D, Choi HJ, Kim JW, Chang H, Bao L, Sun H, Mercade TM, Xie F, Metges JP, Jieer Y, Bridgewater JA, Tejani MA, Chen EY, Wasan HS, Ducreux MP, Ma J, Garfin PM, Harding JJ. Results from the pivotal phase (Ph) 2b HERIZON-BTC-01 study: Zanidatamab in previously-treated HER2-amplified biliary tract cancer (BTC). ASCO 2023, 2023. e-Pub 2023.
- Pant S, Yaeger R, Spira AI, Pelster M, Sabari JK, Hafez N, Barve MA, Velastegui K, Yan X, Der-Torossian H, Bekaii-Saab TS. KRYSTAL-1: Activity and safety of adagrasib (MRTX849) in patients with advanced solid tumors harboring a KRASG12C mutation. ASCO 2023, 2023. e-Pub 2023.
- Papadopoulos KP, Tehfe M, Abdul Razak AR, Pant S, Chung V, Rasco DW, Jamal R, Willis J, Antrás JF, Brettschneider K, Zamorski A, Bähr-Mahmud H, Koseoglu S, Chang PK, Lindemann C, Schlitter AM, Magenheim R, Mattos-Arruda LD, Türeci Ö, Sahin U. A phase I/II dose escalation and expansion trial to evaluate safety and preliminary efficacy of BNT141 in patients with claudin-18.2-positive solid tumors. ASCO 2023, 2023. e-Pub 2023.
- George GC, Piha-Paul SA, Fu S, Ahnert JR, Yap TA, Subbiah V, Dumbrava EE, Tsimberidou AM, Pant S, Appleton G, Noor L, Meric-Bernstam F, Cleeland CS, Mendoza TR, Hong DS. Baseline symptom, health status, and health utilities in patients in early-phase clinical trials combining immune checkpoint blockade with other anticancer therapies. ASCO 2023, 2023. e-Pub 2023.
- Johnson B, Willis J, Williams C, Wang X, Smith GL, You Y, Dumbrava EE, Fu S, Karp DD, Naing A, Piha-Paul SA, Ahnert JR, Tsimberidou AM, Yap TA, Overman MJ, Pant S, Hong DS, Kopetz S, Meric-Bernstam F, Subbiah V. Molecular landscape and survival outcomes on early phase clinical trials in sporadic young onset colorectal cancer. ASCO 2023, 2023. e-Pub 2023.
- O'Reilly EM, Wainberg ZA, Weekes CD, Furqan M, Kasi PM, Devoe CE, Leal AD, Chung V, Perry J, Seenappa L, McNeil L, Welkowsky E, DeMuth P, Haqq CM, Pant S. AMPLIFY-201, a first-in-human safety and efficacy trial of adjuvant ELI-002 2P immunotherapy for patients with high-relapse risk with KRAS G12D- or G12R-mutated pancreatic and colorectal cancer. AMPLIFY-201, a first-in-human safety and efficacy trial of adjuvant ELI-002 2P immunotherapy for patients with high-relapse risk with KRAS G12D- or G12R-mutated pancreatic and colorectal cancer, 2023. e-Pub 2023.
- Harding JJ, Hofheinz R, Elez E, Kuboki Y, Rasco DW, Cecchini M, Shen L, He M, Archuadze S, Chhaya N, Pant S. A phase Ia/b first-in-human, open-label, multicenter study of BI 905711, a bispecific TRAILR2 agonist, in patients with advanced gastrointestinal cancers. ASCO2023, 2023. e-Pub 2023.
- Pant S, Schuler MH, Iyer G, Witt O, Doi T, Qin S, Tabernero J, Reardon DA, Massard C, Welsh L, Lugowska IA, Carranza O, Stuyckens K, Liao H, Najmi S, Hammond C, Thomas S, Triantos S, Sweiti H, Loriot Y. Tumor agnostic efficacy and safety of erdafitinib (erda) in patients (pts) with advanced solid tumors with prespecified FGFR alterations (FGFRalt): RAGNAR primary analysis. 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
- O'Reilly EM, Melisi D, Macarulla T, Pazo Cid RA, Chandana SR, La Fouchardiere CD, Dean AP, Kiss I, Lee WJ, Goetze TO, Cutsem EV, Paulson S, Bekaii-Saab TS, Pant S, Hubner R, Xiao Z, Chen H, Benzaghou F, Wainberg ZA. Liposomal irinotecan + 5-fluorouracil/leucovorin + oxaliplatin (NALIRIFOX) versus nab-paclitaxel + gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): 12- and 18-month survival rates from the phase 3 NAPOLI 3 trial. ASCO 2023, 2023. e-Pub 2023.
- Johnson B, Willis J, Williams C, Wang X, Smith GL, You Y, Dumbrava EE, Fu S, Karp DD, Naing A, Piha-Paul SA, Ahnert JR, Tsimberidou AM, Yap TA, Overman MJ, Pant S, Hong DS, Kopetz S, Meric-Bernstam F, Subbiah V. Molecular landscape and survival outcomes on early phase clinical trials in sporadic young onset colorectal cancer. ASCO 2023, 2023. e-Pub 2023.
- Morelli MP, Negrao MV, Collinson-Pautz MR, Jernigan K, Demars NA, Weitzman A, Adeyemi F, Carpio VH, Jazaeri AA, Johnson B, Pant S, Kebriaei P, Srivastava AK, Deniger DC, Heymach J, Kopetz S. Safety and efficacy of Sleeping Beauty TCR-T cells targeting shared KRAS and TP53 mutations expressed by solid tumors in first-in-human phase 1 study. 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
- Pant S, Yaeger R, Spira AI, Pelster M, Sabari JK, Hafez N, Barve MA, Velastegui K, Yan X, Der-Torossian H, Bekaii-Saab TS. KRYSTAL-1: Activity and safety of adagrasib (MRTX849) in patients with advanced solid tumors harboring a KRASG12C mutation. ASCO 2023, 2023. e-Pub 2023.
- Cecchini M, Chao J, Shyr Y, Cleary J, Uboha N, Cho M, Shields A, Pant S, Goff L, Spencer K, Kim E, C-Y H, Stein S, Thumar J, Kortmansky J, Kunstman J, LoRusso P, Ivy P, Lacy J. A phase 1 / 2 study of olaparib in combination with ramucirumab in metastatic gastric and gastroesophageal junction adenocarcinoma (GEJ). PO.CT02.02 - Phase II Clinical Trials 2, 2022. e-Pub 2022.
- Moyers J, Nguyen D, Hong DS, Dumbrava E, Fu S, Karp D, Naing A, SPant, Janku F, Piha-Paul S, Rodon J, Subbiah V, Tsimberidou AM, Meric-Bernstam F, Yap T. Adherence to the Food and Drug Administration (FDA) Guidance for the Co-Development of Two or More Investigational New Drugs in Phase 1/2 Cancer Trials. ESMO Congress 2021, 2021. e-Pub 2021.
- Johnson ML, Gort E, Pant S, Lolkema MP, Sebastian M, Scheffler M, Hwang J, Dünzinger U, Riemann K, Kitzing T, Jänne PA. A phase I, open-label, dose-escalation trial of BI 1701963 in patients (pts) with KRAS mutated solid tumours: A snapshot analysis. ESMO Congress 2021, 2021. e-Pub 2021.
- Parra ER, Adriani M, Lima C, Li J, Haymaker C, Parikh R, Bernicker E, Davar D, Chaudhry A, Stevenson A, Badham C, Fyvie G, Chisamore M, Pant S. Baseline biomarkers associated with clinical benefit in patients with solid tumors refractory to immune checkpoint inhibitors (ICIs) treated with live biotherapeutic MRx0518 in combination with pembrolizumab. ESMO Congress 2021, 2021. e-Pub 2021.
- Borazanci E, Hallak MN, Eder JP, Golan T, Pant S, Perets R, Markel G, Schickler M, Reuveni H, Jin L, Liang B. A phase Ib study of CM24 in combination with nivolumab in adults with advanced solid tumors, followed by a phase IIa study of CM24 in combination with nivolumab in NSCLC, and in combination with nivolumab and nab-paclitaxel in pancreatic cancer. ESMO Congress 2021, 2021. e-Pub 2021.
- Alhalabi O, Naing A, Groisberg R, Hahn A, Zhang S, Berkey SC, Tsimberidou AM, Rodon J, Yap TA, Pant S, Shah AY, Zurita-Saavedra A, Tannir N, Meric-Bernstam F, Subbiah V. Phase I study of mTORC1-2 inhibitor sapanisertib (TAK-228) in combination with carboplatin plus paclitaxelin patients with advanced solid malignancies and mTOR pathway alterations, 2021. e-Pub 2021.
- Lin C, Zucali P, Carthon B, Bauer TM, Tucci M, Italiano A, Iacovelli R, Su W, Massard C, Saleh M, Daniele G, Greystoke A, Gutierrez M, Pant S, Shen Y, Perrino M, Meng R, Abbadessa G, Lee H, Dong Y, Chiron M, Wang R, Loumagne L, Bono JD, Bono JD. Targeting CD38 and PD-1 with isatuximab (Isa) plus cemiplimab (Cemi) in patients (pts) with advanced malignancies: Results from a Phase 1/2 open-label, multicenter study, 2021. e-Pub 2021.
- Coleman N, Abbot C, Somaiah N, Piha-Paul S, Pant S, Rodon J, Call S, Boyle S, Meric-Bernstam F, Janku F. Whole exome sequencing of tumor tissue and circulating tumor DNA ingastrointestinal stromal tumors (GIST), 2021. e-Pub 2021.
- Subbiah IM, Buzdar A, Ileana Dumbrava EE, Fu S, Janku F, Karp DD, Naing A, Pant S, Rodon J, Tsimberidou AM, Yap TA, Subbiah V, Meric-Bernstam F, Hong DS. Investigating the disparate enrollment of older adults on phase I clinical trials: evolving participation patterns of patients 65 years and older w advanced cancer on phase I trials. J Clin Oncol ASCO Annual Meeting 2020 38, 2020. e-Pub 2020.
- Gouda MA, Huang HJ, Piha-Paul SA, Call S, Karp DD, Fu S, Naing A, Subbiah V, Pant S, Tsimberidou AM, Hong DS, Ahnert JR, Meric-Bernstam F, Janku F. Genomically Informed Longitudinal Monitoring of Circulating Tumor DNA (ctDNA) Predicts Outcomes of Cancer Therapy. J Clin Oncol ASCO Meeting 2020 38, 2020. e-Pub 2020.
- Moser EC, Hoffe SE, Frakes J, Aguilera TA, Karim M, Colbert LE, Moningi S, Tzeng CD, Thall PF, Pant S, Bhutani MS, Brookes M, Holmlund J, Herman JM, Taniguchi CM. Adaptive dose optimization trial of stereotactic body radiation therapy (SBRT) with or without GC4419 (avasopasem manganese) in pancreatic cancer. J Clin Oncol, 2020 ASCO Meeting 38, 2020. e-Pub 2020.
- Alhalabi O, Hahn AW, Meric-Bernstam F, Naing A, Piha-Paul SA, Janku F, Pant S, Yap TA, Hong DS, Fu S, Campbell E, Le H, Shah AY, Campbell MT, Tannir NM, Siefker-Radtke AO, Gao J, Roszik J, Subbiah V. Outcomes and the impact of genomic characteristics on patients with metastatic urothelial carcinoma enrolled in early phase trials. J Clin Oncol ASCO Meeting 2020 38, 2020. e-Pub 2020.
- Gort E, Johnson ML, Hwang JJ, Pant S, Dünzinger U, Riemann K, Kitzing T, Janne PA. A phase I, open-label, dose-escalation trial of BI 1701963 as monotherapy and in combination with trametinib in patients with KRAS mutated advanced or metastatic solid tumors. J Clin Oncol, 2020 ASCO Meeting 38, 2020. e-Pub 2020.
- Huey R, George G, Phillips P, White R, Fu S, Janku F, Karp DD, Naing A, Piha-Paul SA, Subbiah V, Tsimberidou AM, Pant S, Yap TA, Ahnert JR, Meric-Bernstam F, Shih YT, Hong DS. Patient-Reported Out-of-Pocket Costs and Financial Toxicity During Early-Phase Oncology Clinical Trials. J Clin Oncol ASCO Meeting 2020 38, 2020. e-Pub 2020.
- Pant, S. Erdafitinib for advanced solid tumors: A phase 2, open-label efficacy and safety study in adult and adolescent patients (pts) with advanced solid tumors harboring fibroblast growth factor receptor (FGFR) gene alterations, 2020. e-Pub 2020.
- Pant, S. Tyme-88-Panc Part 2: A randomized phase II/III of SM-88 with MPS as third-line in metastatic PDAC, 2020. e-Pub 2020.
- Pant S, et al. Safety and efficacy signals in the complete phase I study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitors (ICIs), SITC, 2020. Safety and efficacy signals in the complete phase I study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitors (ICIs), SITC, 2020, 2020. e-Pub 2020.
- Pant S, et al. A phase I/II study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitors. A phase I/II study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitors, 2020. e-Pub 2020.
- Hahn AW, Alhalabi O, Meric-Bernstam F, Naing A, Jonasch E, Msaouel P, Piha-Paul SA, Hong DS, Pant S, Yap TA, Campbell E, Le H, Tannir NM, Roszik J, Subbiah V. Phase I clinical trials as a therapeutic option for patients with metastatic renal cell carcinoma (mRCC). J Clin Oncol, ASCO Meeting 2020 38, 2020. e-Pub 2020.
- Pant, S, Mulder I, Shah AY, Msaouel P, Altan M, Weinberg J, Stevenson A, Meric-Bernstam F, Yap TA, Subbiah V, Ahnert JR. A phase I/II study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients who have progressed on prior anti-PD-1 therapy. J Clin Oncol; Proceedings of the 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
- Moss TJ, Ahnert JR, Oakley HD, Kahle M, Karp DD, Pant S, Jacob J, Raymond VM, Lanman RB, Kwong L, Routbort M, Soni N, Huang J, Javle MM, Meric-Bernstam F. Baseline cfDNA characteristics and evolution of cfDNA profile during treatment with selective FGFR inhibitor TAS-120. J Clin Oncol, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Yap TA, Ahnert JR, Piha-Paul SA, Fu S, Janku F, Karp DD, Naing A, Ileana Dumbrava EE, Pant S, Subbiah V, Tsimberidou AM, Hong DS, Rose KM, Xu Q, Vellano CP, Mahendra M, Jones P, Di Francesco ME, Marszalek JR, Meric-Bernstam F. Phase I trial of IACS-010759 (IACS), a potent, selective inhibitor of complex I of the mitochondrial electron transport chain, in patients (pts) with advanced solid tumors. J Clin Oncol, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Mohindroo C, Rogers J, Hasanov M, Mizrahi J, Overman M, G, Varadhachary R, Wolff R, Javle M, Fogelman D, Pant <, . A retrospective analysis of antibiotics usage and effect on overall survival and progressive free survival in patients with metastatic pancreatic cancer. ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Wang-Gillam A, O'Reilly EM, Bendell JC, Wainberg ZA, Borazanci EH, Bahary N, O'Hara MH, Beatty GL, Pant S, Cohen DJ, Leong S, Beg MS, Yu KH, Evans TR, Seufferlein T, Okusaka T, Phillips P, Liu X, Perna SK, Le DT. A randomized phase II study of cabiralizumab (cabira) + nivolumab (nivo) ± chemotherapy (chemo) in advanced pancreatic ductal adenocarcinoma (PDAC). J Clin Oncol, 2019 Gastrointestinal Cancers Symposium, 2019. e-Pub 2019.
- Pant, S, Lamar, M, Kazakin, J, Savage, R, Schwartz, B, Hall, T. The use of biomarkers and ctDNA in a phase 1 trial of ARQ 751. Mol Cancer Ther, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, 2019. e-Pub 2019.
- Cohen DJ, Pant S, O'Neil B, Marinis J, Winnberg J, Ahlers CM, Callaway J, Rathi C, Acusta A, Verticelli A, Bertin J, Smothers JF. A phase I/study of GSK3145095 alone and in combination with anticancer agents including pembrolizumab in adults with selected solid tumors. J Clin Oncol. ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Mizrahi J, Rogers J, Hess KR, Wolff RA, Varadhachary GR, Shroff RT, Ho L, Fogelman DR, Singh Raghav KP, Overman MJ, Pant S. FOLFIRINOX in pancreatic cancer patients age 75 years or older. J Clin Oncol, 2019 Gastrointestinal Cancers Symposium, 2019. e-Pub 2019.
- Huey R, George G, Phillips P, White R, Fu S, Janku F, Karp DD, Naing A, Piha-Paul SA, Subbiah V, Tsimberidou AM, Pant S, Yap TA, Ahnert JR, Meric-Bernstam F, Shih YT, Hong DS. Out of pocket costs and financial toxicity experienced by patients in early phase clinical trials. J Clin Oncol, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Yap TA, Ahnert JR, Piha-Paul SA, Fu S, Janku F, Karp DD, Naing A, Ileana Dumbrava EE, Pant S, Subbiah V, Tsimberidou AM, Hong DS, Rose KM, Xu Q, Vellano CP, Mahendra M, Jones P, Di Francesco ME, Marszalek JR, Meric-Bernstam F. Phase I trial of IACS-010759 (IACS), a potent, selective inhibitor of complex I of the mitochondrial electron transport chain, in patients (pts) with advanced solid tumors. J Clin Onc, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Johnson B, Loree JM, Morris VK, Dasari A, Pant S, Singh Raghav KP, Kopetz S. Activity of EGFR inhibition in atypical (non-V600E) BRAF-mutated metastatic colorectal cancer. J Clin Oncol, 2019 Gastrointestinal Cancers Symposium, 2019. e-Pub 2019.
- Naing A, Meric-Bernstam F, Karp D, Rodon JA, Piha-Paul SA, Subbiah V, Hong DS, Pant S, Fu S, Janku F, Yap TA, Tsimberidou AM, Dumbrava EE, Colen RR, Hess KR, Campbell MT, Tu S, Jimenez C, Habra MA, Varadhachary GR. Pembrolizumab in Advanced Rare Cancers. Annals of Oncology, ESMO Congress 2019, 2019. e-Pub 2019.
- Pant, Bendell S, Sullivan RJ, Shapiro G, Millward M, Mi G, Yuen E, Willard MD, Wang D, Joseph S, McMillen WT, Bhagwat SV, Tiu RV, Patel MR. A phase I dose escalation (DE) study of ERK inhibitor, LY3214996, in advanced (adv) cancer (CA) patients (pts. J Clin Oncol, Annual Meeting 2019 SITC, 2019. e-Pub 2019.
- Sachdev JC, Bauer TM, Chawla SP, Pant, S S, Patnaik A, Wainberg ZA, Inamdar SP, Marina N, Sun S, Schmidt M, Xiang H, LoRusso P. Phase 1a/1b study of first-in-class B7-H4 antibody, FPA150, as monotherapy in patients with advanced solid tumors. J Clin Oncol, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Kurnit KC, Meric-Bernstam F, Hess K, Coleman RL, Bhosale P, Savelieva K, Janku F, Hong D, Naing A, SPant S, Rodon J, Yap TA, Sood AK, Soliman PT, Gershenson DM, Mills GB, Westin SN. Phase I dose escalation of olaparib (PARP inhibitor) and selumetinib (MEK Inhibitor) combination in solid tumors with Ras pathway alterations. AACR Annual Meeting 2019, 2019. e-Pub 2019.
- Wainberg ZA, Sachdev JC, Bauer T, Pant S, Chawla S, Marina N, Xiang H, Deng W, Schmidt M, Patnaik A, LoRusso P. FPA150 (B7-H4 antibody) Phase 1 Update in Advanced Solid Tumors: Monotherapy and in Combination with Pembrolizumab. Annals of Oncol, ESMO Congress 2019, 2019. e-Pub 2019.
- Ocean A, Noel M, Wang-Gillam A, Chawla S, Chung V, Pant S, Korn R, Priore G, Picozzi V. Phase II Monotherapy Efficacy of Cancer Metabolism Targeting SM-88 in Heavily Pre-Treated PDAC Patients. Annals of Oncol, ESMO Congress 2019, 2019. e-Pub 2019.
- Janku F, Sen S, Pant S, Bramwell L, Subbiah V, Way T, Javle MM, Stone C, Prajapati B, Hagiwara S, Johansen M, Madden T, Maier G, Subach RA, Saeki K, Suzuki T, Wages DS, Wheeler CA, Falchook GS. Phase 1/2 trial of FF-10502-01, a pyrimidine antimetabolite, in patients with advanced cholangiocarcinoma and solid tumors. J Clin Oncol, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Hegde A, MD, Jayaprakash P, PhD, Sumner E, Nguyen D, Zain H, Piha-Paul SA, MD, Karp D, Rodon J, Pant, S, Fu S, MD, PhD, Ecaterina I. A Phase 1 Dose Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies. SITC Annual Meeting 2019, 2019. e-Pub 2019.
- Pestana RC, Subbiah IM, Hess KR, Huang L, Liu S, Beltran K, Harrison H, Bryant A, Eshon J, Yap TA, S, Pant, Naing A, Hong DS, Meric-Bernstam F, Subbiah V. Re-evaluating eligibility criteria: Analysis of factors leading to nonparticipation and outcomes of patients (pt) with advanced cancer who signed consent but were not treated in early-phase. J Clin Oncl, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Hasanov M, Mohindroo C, Rogers J, Prakash L, Overman MJ, Varadhachary GR, Wolff RA, Javle MM, Fogelman DR, Pant S, G Katz MH, Kim MP, Tzeng CD, McAllister F. The effect of antibiotic use on survival of patients with resected pancreatic ductal adenocarcinoma. J Clin Oncol, ASCO Annual Meeting 2019, 2019. e-Pub 2019.
- Fogelman DR, MD, Overman M, MD, Wolff R, Javle M, MD, Pant, S, MBBS, Varadhachary G, Shroff RT, Wistuba I, MD, Barreto CM, PhD, Renganayaki. A phase IIB study of Pembrolizumab plus BL-8040 in metastatic pancreatic cancer: Clinical outcomes and biological correlates, 2018. e-Pub 2018.
- Pant, S, Subbiah V, Rodon J, Janku F, Hong D, Karp D, Piha-Paul S, Tsimberidou AM, Naing A, Fu S, Savage RE, Chai F, Yu Y, Tith K, Alfattal R, Schwartz B, Meric-Bernstam F, Yap T. A phase 1 dose escalation study of ARQ 751 in adult patients with advanced solid tumors with AKT1, 2, 3 genetic alterations, activating PI3 K mutations, PTEN-null, or other known actionable PTEN mutations". J Clin Oncol., AACR Annual Meeting 2018, 2018. e-Pub 2018.
- Pant S, Spira AI, Cho BC, Goel S, Hoimes CJ, Alva AS, Balaraman R, Bauer TM, Lowry PA, Ramaekers RC, Siegel RD, Verner TL, Tannier NM, Faltaos D, Potvin D, Neuteboom STC, Christensen J, Chao RC, Kyriakopoulos. Evaluation of the spectrum selective RTK inhibitor sitravatinib in clear cell renal cell carcinoma (ccRCC) refractory to anti-angiogenic therapy (AAT). J Clin Oncol, 2018 ASCO Annual Meeting Proceedings 36, 2018. e-Pub 2018.
- Kheder E, Hess KR, Xing Y, Cortez MA, Subbiah V, Janku F, Fu S, Naing A, Karp DD, Piha-Paul SA, Yap TA, Pant S, Rodon Ahnert J, Tawbi HA, Welsh JW, Meric-Bernstam F, Hong DS. TP53 mutations and programmed cell death ligand-1 expression in solid tumors: Associations with clinical factors and outcomes. J Clin Oncol, ASCO Annual Meeting 2018, 2018. e-Pub 2018.
- Tannir NM, Naing A, Infante JR, Papadopoulos KP, Wong DJL, Korn M, Aljumaily R, Autio KA, Pant S, Bauer TM, Drakaki A, Daver NG, Hung A, Van Vasselaer P, Leveque J, Oft M. Pegilodecakin with nivolumab (nivo) or pembrolizumab (pembro) in patients (pts) with metastatic renal cell carcinoma (RCC). J Clin Oncol, 2018 ASCO Annual Meeting Proceedings 36, 2018. e-Pub 2018.
- Lam M, Pereira AAL, Loree JM, Advani SM, Overman MJ, Johnson A, Holla V, Khotskaya Y, Sanchez NS, Meric-Bernstam F, Kopetz S, Pant S. Effect of matched therapy in metastatic colorectal cancer on progression free survival in the phase I setting. J Clin Oncol, 2018 ASCO Annual Meeting Proceedings 36, 2018. e-Pub 2018.
- Mita MM, Mita AC, Chmielowski B, Hamilton EP, Pant S, Waltzman RJ, Rowinsky EK, Szarek M, Gonsales F, Kurth I, Andreu C, Busby R, Darst DM, Tavozoie SS, Tavozoie M, Postow MA. Pharmacodynamic and clinical activity of RGX-104, a first-in-class immunotherapy targeting the liver-X nuclear hormone receptor (LXR), in patients with refractory malignancies. J Clin Oncol, 2018 ASCO Annual Meeting Proceedings 36, 2018. e-Pub 2018.
- Piha-Paul SA, Fu S, Hong DS, Janku F, Karp DD, Naing A, Pant S, Rodon Ahnert J, Subbiah V, Tsimberidou AM, Yap TA, Meric-Bernstam F. Phase I study of the pan-HER inhibitor neratinib given in combination with everolimus, palbociclib or trametinib in advanced cancer subjects with EGFR mutation/amplification, HER2 mutation/amplification or HER3/4 mutation. J Clin Oncol, 2018 ASCO Annual Meeting Proceedings 36, 2018. e-Pub 2018.
- Pant S, Subbiah V, Rodon J, Janku F, Hong DS, Karp D, Piha-Paul SA, Tsimberidou AM, Naing A, Fu S, Savage RE, Chai F, Yu Y, Schwartz B, Meric-Bernstam F, Yap T. Results of a phase I dose escalation study of ARQ 751 in adult subjects with advanced solid tumors with AKT1, 2, 3 genetic alterations, activating PI3K mutations, PTEN-null, or other known actionable. AACR Annual Meeting 2018, 2018. e-Pub 2018.
- Hecht JR, Naing A, Falchook GS, Patel MR, Infante JR, Aljumaily R, Wong DJ, Autio KA, Wainberg ZA, Javle MM, Bendell JC, Pant S, Hung A, Van Vlasselaer P, Leveque J, Oft M, Papadopoulos KP. Overall survival of PEGylated pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in metastatic pancreatic adenocarcinoma (PDAC). J Clin Oncol, ASCO Annual Meeting 2018, 2018. e-Pub 2018.
- Ferrarotto R, Glisson B, Blumenschein G, Hong D, Piha-Paul S, Ahnert J, Pant S, Tsimberidou A, Janku F, Alshawa A, Jain D, Rejon M, Hess K, Colen R, Lu C, Stephen B, Tapia C, Mendoza T, Meric-Bernstam F, Naing A. Efficacy of pembrolizumab in patients with adrenocortical carcinoma. Eur J Cancer;-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium, 2018. e-Pub 2018.
- Subbiah V, Erwin W, Mawlawi O, Gonzalez-Lepera C, Tokura M, Kurman M, Liu H, Hong DS, Meric-Bernstam F, S P, Johansen M, Madden T, Santos E, Ravizzini G. Phase 1 study of FF-21101(90Y), a radioimmunotherapeutic (RIT) targeting P-cadherin, in advanced solid tumors. Cancer Res., AACR Annual Meeting 2018, 2018. e-Pub 2018.
- Hecht JR, Naing A, Falchook GS, Patel MR, Infante JR, Aljumaily R, Wong DJ, Autio KA, Wainberg ZA, Javle MM, Bendell JC, Pant S, Hung A, Van Vlasselaer P, Oft M, Papadopoulos KP. Overall survival of PEGylated human IL-10 (AM0010) with 5-FU/LV and oxaliplatin (FOLFOX) in metastatic pancreatic adenocarcinoma (PDAC). J Clin Oncol.ASCO Gastrointestinal Cancers Symposium, 2018. e-Pub 2018.
- Ferrarotto R, Glisson B, Blumenschein G, Hong D, Piha-Paul S, Ahnert J, Pant S, Tsimberidou A, Janku F, Alshawa A, Jain D, Rejon M, Hess K, Colen R, Lu C, Stephen B, Tapia C, Mendoza T, Meric-Bernstam F, Naing A. Efficacy of pembrolizumab in patients with cutaneous squamous cell carcinoma. Eur J Cancer;-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium, 2018. e-Pub 2018.
- Ileana Dumbrava E, Balaji K, Raghav K, Javle M, Blum-Murphy M, Sajan B, Kopetz S, Boraddus R, Routbort M, Pant S, TsimberidouA, Subbiah V, Hong DS, Rodon Ahnert J, Shaw K, Piha-Paul S, Meric-. Targeting HER2 (ERBB2) amplification identified by next-generation sequencing (NGS) in patients with advanced or metastatic solid tumors. AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, 2018. e-Pub 2018.
- Lam M, Pereira AA, Loree JM, Advani SM, Overman MJ, Bailey A, Johnson A, Holla V, Sanchez NS, Khotskaya Y, Meric-Bernstam F, Kopetz S, Pant S. Effect of matched therapy in metastatic colorectal cancer on progression free survival in the phase I setting. J Clin Oncol, 2018 ASCO Annual Meeting Proceedings 36(Suppl 4S), 2018. e-Pub 2018.
- Subbiah V, Erwin W, Mawlawi O, Lepera CG, Tokura M, Kawakami M, Liu H, Pant S, Rosner M, Johansen M, Palatis LD, Myers T, Paradiso L, Santos E, Cancer Center GRUOTMA, Houston, TX, Corporation F, Tokyo, Japan, Pharmaceuticals F, USA, Inc, Cambridge, MA, Therapeutics S, Inc, Houston, TX. Phase 1 study of FF-21101(90Y), a radioimmunotherapeutic targeting P-cadherin, in advanced solid tumors. Cancer Res; Proceedings of the AACR Annual Meeting 2017 17(19), 2017. e-Pub 2017.
- Parseghian C, Patnana M, Bhosale P, Hess K, Kopetz S, Overman M, Naing A, Piha-Paul S, Subbiah V, Hong D, Le H, Pant S. Evaluating for pseudoprogression in colorectal and pancreatic tumors treated with immunotherapy. Ann Oncol, ESMO World Congress on Gastrointestinal Cancer 2017 28(Suppl 3), 2017. e-Pub 2017.
- Varadhachary GR, Singh Raghav KP, Pant S, Janku F, Fu S, Hong DS, Piha-Paul SA, Colen RR, Subbiah V, Painter J, Tsimberidou AM, Stephen B, Karp DD, McQuinn L, Mendoza TR, Hess KR, Meric-Bernstam F, Naing A. Phase II Study for the Evaluation of Efficacy of Pembrolizumab (MK-3475) in Patients with Cancer of Unknown Primary. J. Clin Oncol, ASCO Annual Meeting 2017, 2017. e-Pub 2017.
- Pant S, Wheler JJ, Fu S, Hong DS, Karp DD, Subbiah V, Tsimberidou AM, Holley VR, Brewster AM, Higginbotham Koenig K, Ibrahim NK, Murthy RK, Meric-Bernstam F, Janku F. Proof-of concept phase I study of everolimus, letrozole and trastuzumab in hormone receptor-positive, HER2-positive/amplified or mutant metastatic breast cancer or other solid tumors: Evaluating synergy and overcoming resistance. J Clin Oncol; Proceedings of the 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Hecht JR, Naing A, Falchook GS, Patel MR, Infante JR, Aljumaily R, Wong DJL, Autio KA, Wainberg ZA, Javle MM, Bendell JC, Pant S, Van Vlasselaer P, Brown GL, Oft M, Papadopoulos KP. Phase 1b study with PEGylated human IL-10 (AM0010) with 5-FU and oxaliplatin (FOLFOX) in metastatic pancreatic adenocarcinoma (PDAC). 2017 Gastrointestinal Cancers Symposium, 2017. e-Pub 2017.
- Naing A, Lopez-Berestein G, Fu S, Tsimberidou AM, Pant S, Piha-Paul SA, Janku F, Hong DS, Sulovic S, Meng X, Jazaeri AA, Ng CS, Karp DD, Subbiah V, Meric-Bernstam F, Mitra R, Wu S, Sood A, Coleman RL. EphA2 gene targeting using neutral liposomal small interfering RNA (EPHARNA) delivery: A phase I clinical trial. J Clin Oncol, 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Naing A, Infante JR, Wong DJ, Korn MW, Aljumaily R, Papadopoulos K, Autio K, Pant S, Bauer TM, Drakaki A, Daver N, Hung A, Van Vlasselaer P, Brown G, Oft M, Tannier N. Immune correlates for the efficacy of PEGylated Human IL-10 (AM0010) with nivolumab in renal cell cancer. Ann Oncology, ESMO 2017 Congress, 2017. e-Pub 2017.
- Naing A, Infante JR, Wong DJL, Korn WM, Aljumaily R, Papadopoulos KA, Autio KA, Pant S, Bauer TM, Drakaki A, Daver NG, Hung A, Van Vlasselaer P, Brown GL, Oft M, Tannir NM. Efficacy and safety of pegylated human IL-10 (AM0010) in combination with an anti-PD-1 in renal cell cancer. J Clin Oncol, 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Hecht JR, Naing A, Falchook GS, Patel MR, Infante JR, Aljumaily R, Wong DJL, Autio KA, Wainberg ZA, Javle MM, Bendell JC, Pant S, Hung A, Van Vlasselaer P, Brown GL, Oft M, Papadopoulos K. Immunologic and objective tumor responses to PEGylated human IL-10 (AM0010) with 5-FU/LV and oxaliplatin (FOLFOX) in metastatic pancreatic adenocarcinoma (PDAC). ESMO World Congress on Gastrointestinal Cancer 2017, 2017. e-Pub 2017.
- Sen S, Piha-Paul SA, Kato S, Karp DD, Janku F, Fu S, Pant S, Tsimberidou AM, Subbiah V, Kurzrock R, Meric-Bernstam F, Hong DS. Phase I study of nab-paclitaxel, gemcitabine, and bevacizumab in advanced cancers. J Clin Oncol, 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Hecht JR, Falchook GS, Patel MR, Aljumaily R, Infante JR, Naing A, Wong DJL, Autio KA, Ratti N, Wainberg ZA, Bendell JC, Pant S, Brown GL, Van Vlasselaer P, Oft M, Papadopoulos KP. Efficacy, safety, and immune activation with pegylated human IL-10 (AM0010) plus FOLFOX in metastatic pancreatic adenocarcinoma (PDAC). J Clin Oncol, 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Naing A, Wong DJL, Infante JR, Patel MR, Pant S, Chmielowski B, Janku F, Tapia C, Ratti N, Van Vlasselaer P, Brown GL, Hung A, Oft M, Diab A. PEGylated human IL-10 (AM0010) in combination with pembrolizumab in anti-PD1 and CTLA-4 refractory melanoma. J Clin Oncol, 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Piha-Paul SA, Xiong WW, Moss T, Mostorino RM, Sedelmeier S, Hess K, Fu S, Hong DS, Janku F, Karp D, Naing A, Pant S, Rodon J, Subbiah V, Tsimberidou AM, Yap T, Javle M, Tapia C, Shaw KR, Eterovic K, Mills GB, Meric-Bernstam F. Phase II study of the PARP inhibitor talazoparib in advanced cancer patients with somatic alterations in BRCA1/2, mutations/deletions in PTEN or PTEN loss, aberrations in other BRCA pathway genes, and germline mutations in BRCA1/2 (not breast or ovarian cancer). Mol Cancer Ther, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, 2017. e-Pub 2017.
- Mita M, Mita A, Chmielowski B, Postow M, Hamilton E, Pant S, Waltzman R, Rowinsky E, Szarek M, Gonsalves F, Kurth I, Andreu C, Pollack I, Mucida D, Tanqueco R, Tavozoie M. A phase 1 trial of RGX-104, a first-in-class immunotherapy targeting the liver-X nuclear hormone receptor (LXR), in patients with refractory malignancies. Mol Cancer Ther, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, 2017. e-Pub 2017.
- Naing A, Fu S, Tsimberidou AM, Pant S, Piha-Paul SA, Janku F, Hong DS, Colen RR, Carter BW, Evans E, Tawbi HAH, Karp DD, Subbiah V, Dev R, Hess KR, Ueno NT, Simon GR, Overman MJ, Coleman RL, Meric-Bernstam F. Phase IB study to evaluate the safety of selinexor in combination with multiple standard chemotherapy agents in patients with advanced malignancies. J Clin Oncol, 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Pant S, Owonikoko TK, Diefenbach CS, Kim S, Chen Z, Towle EL, Pierce LJ, Mileham KF. Collection and utilization of oncology big data, 2017. e-Pub 2017.
- Pant S, Wheler JJ, Fu S, Hong DS, Karp DD, Subbiah V, Tsimberidou AM, Holley VR, Brewster AM, Higginbotham Koenig K, Ibrahim NK, Murthy RK, Meric-Bernstam F, Janku F. Proof-of concept phase I study of everolimus, letrozole and trastuzumab in hormone receptor-positive, HER2-positive/amplified or mutant metastatic breast cancer or other solid tumors: Evaluating synergy and overcoming resistance. J Clin Oncol. 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
- Hecht JR, Naing A, Falchook GS, Patel MR, Infante JR, Aljumaily R, Wong DJ, Autio K, Wainberg ZA, Javle M, Bendell JC, Pant S, Hung A, Van Vlasselaer P, Brown G, Oft M, Papadopoulos K. Overall survival and immunologica responses in metastatic pancreatic adenocarcinoma (PDAC) on PEGylated human IL-10 (AM0010) with 5-FU/LV and oxaliplatin (FOLFOX). Ann Oncol, ESMO 2017 Congress, 2017. e-Pub 2017.
- Dembla V, Ray D, Lockett P, Fullmer C, Subramanian H, Subbiah V, Fu S, Janku F, Tsimberidou AM, Naing A, Piha-Paul SA, Hong DS, Pant S, Miller VA, Lim J, Le H, Karp DD. Drug development in the MD Anderson Cancer Center (MDACC) Clinical Translational Research Center (CTRC) - 2011-2015: The challenge of precision medicine in a very broad playing field 68(1), 2016. e-Pub 2016.
- Naing A, Papadopoulos KP, Autio KA, Wong DJ, Patel M, Falchook G, Pant S, Ott PA, Whiteside M, Patnaik A, Mumm J, Janku F, Chan I, Bauer T, Colen R, VanVlasselaer P, Brown GL, Tannir NM, Oft M, Infante J. Immune activation by PEGylated human IL-10 (AM0010) and anti-tumor activity in renal cancer alone and in combination with anti-PD-1. J Immunother Cancer; 31st Annual Meeting of the SITC 2016 4(1), 2016. e-Pub 2016.
- Naing A, Papadopoulos KP, Autio KA, Ott PA, Patel MR, Wong DJ, Falchook GS, Pant S, Whiteside M, Rasco D, Patnaik A, Bendel JC, Bauer TM, Colen RR, Hong DS, Van Vlasselaer P, Oft M, Brown GL, Infante JR, Tannir N. Anti-tumor activity of PEGylated human IL-10 (AM0010) in renal cancer alone and in combination with anti-PD1. Ann Oncol; Abstract Book of the 41st ESMO Congress 27(6), 2016. e-Pub 2016.
- Beeram M, Tolaney SM, Beck J, Dickler MN, Conlin AK, Dees C, Helsten TL, Conkling PR, Edenfield WJ, Richards DA, Kambhampati S, Costigan TM, Chan E, Pant S, Kalinsky K, Burris HA, Becerra CH, Rexer BN, Puhalla SL, Goetz MP. A phase 1b study of abemaciclib, an inhibitor of CDK4 and CDK6, in combination with endocrine and HER2-targeted therapies for patients with metastatic breast cancer 27(6), 2016. e-Pub 2016.
- Wirth LJ, Dakhil S, Kornek G, Axelrod R, Adkins D, Pant S, O'Brien P, Debruyne PR, Oliner KS, Dong J, Murugappan S. PARTNER: An Open-Label, Randomized, Phase 2 Study of Docetaxel/Cisplatin Chemotherapy With or Without Panitumumab as First-Line Treatment for Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck. Oral Oncol 61:31-40, 2016. e-Pub 2016. PMID: 27688102.
- Hamilton EP, Patel M, Gluck WL, Weise AM, Pant S, Fields Jones S, LoRusso P, Kittaneh M, Cosulich S, Harrington EA, Littlewood G, Oelmann EM, Burris HA. A phase I study of continuous (Con) and intermittent (Int) AZD2014 plus fulvestrant (F) in patients (pts) with estrogen receptor (ER+) metastatic breast cancer (BC). J Clin Oncol, 2016 ASCO Annual Meeting 34, 2016. e-Pub 2016.
- Naing A, Papadopoulos KP, Infante RJ, Lee Wong DJ, Autio KA, Ott PA, Falchook GS, Patel MR, Pant S, Patnaik A, Mumm JB, Whiteside M, Chan IH, Bendell JC, Bauer TM, Janku F, Colen RR, Tannir NM, Van Vlasselaer P, Oft M. Clinical activity and safety of pegylated human IL-10 (AM0010) in combination with anti-PD1. 2016 ASCO Annual Meeting, 2016. e-Pub 2016.
- Disis ML, Patel MR, Pant S, Hamilton EP, Lockhart AC, Kelly K, Beck JT, Gordon MS, Weiss GJ, Taylor MH, Chaves J, Mita AC, Chin KM, von Heydebreck A, Cuillerot JM, Gulley JL. Avelumab (MSB0010718C; anti-PD-L1) in patients with recurrent/refractory ovarian cancer from the JAVELIN Solid Tumor phase Ib trial: Safety and clinical activity. 2016 ASCO Annual Meeting, 2016. e-Pub 2016.
- Papadopoulos KP, Naing A, Infante JR, Autio KA, Ott PA, Lee Wong DJ, Falchook GS, Patel MR, Pant S, Whiteside M, Mumm JB, Chan IH, Bendell JC, Rasco DW, Shih KC, Javle MM, Bauer TM, Colen RR, Van Vlasselaer P, Oft M. Anti-tumor activity of PEGylated human IL-10 (AM0010) in patients with pancreatic or colorectal cancer. J Clin Oncol, 2016 ASCO Annual Meeting, 2016. e-Pub 2016.
- Naing A, Papadopoulos KP, Autio KA, Ott PA, Patel MR, Wong DJ, Falchook GS, Pant, S, Whiteside M, Rasco D, Patnaik A, Bendel JC, Bauer TM, Colen RR, Hong DS, Van Vlasselaer P, Oft M, Brown GL, Infante JR, Tannir N. Anti-tumor activity of PEGylated human IL-10 (AM0010) in renal cancer alone and in combination with anti-PD1, 2016. e-Pub 2016.
- Beeram M, Tolaney SM, Beck J, Dickler MN, Conlin AK, Dees C, Helsten TL, Conkling PR, Edenfield WJ, Richards DA, Kambhampati S, Costigan TM, Chan E, Pant, S, Kalinsky K, Burris HA, Becerra CH, Rexer BN. A phase 1b study of abemaciclib, an inhibitor of CDK4 and CDK6, in combination with endocrine and HER2-targeted therapies for patients with metastatic breast cancer. ESMO 2016 Congress, 2016. e-Pub 2016.
- Dean EJ, Falchook GS, Patel MR, Brenner AJ, Infante, JR, Arkenau HT, Borazanci EH, Lopez JS, Pant S, Schmid P, Frankel AE, Fields Jones S, McCulloch W, Kemble G, O'Farrell M, Burris H. Preliminary activity in the first in human study of the first-in-class fatty acid synthase (FASN) inhibitor, TVB-2640. 2016 ASCO Annual Meeting, 2016. e-Pub 2016.
- Dembla V, Ray D, Lockett P, Fullmer C, Subramanian H, Subbiah V, Fu S, Janku F, Tsimberidou AM, Naing A, Piha-Paul SA, Hong DS, Pant, S, Miller VA, Lim J, Le H, Karp DD. Drug development in the MD Anderson Cancer Center (MDACC) Clinical Translational Research Center (CTRC) - 2011-2015: The challenge of precision medicine in a very broad playing field. 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, 2016. e-Pub 2016.
- Chen LT, Siveke JT, Wang-Gillam A, Hubner R, Pant S, Dragovich T, Chung VM, Chang DZ, Ross PJ, Cooray P, Tebbutt NC, Franke FA, Belanger B, Dhindsa N, Jong F, Mamlouk K, Von Hoff DD. Effect of baseline carbohydrate antigen 19-9 (CA19-9) level on overall survival (OS) in NAPOLI-1: A randomized phase III study of MM-398 (nal-IRI), with or without 5-fluorouracil and leucovorin (5-FU/LV), versus 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine (gem)-based therapy. J Clin Oncology, Proceedings of the ASCO 2016 Gastrointestinal Cancers Symposium, 2016. e-Pub 2016.
- Brenner A, Infante J, Patel M, H-T A, Voskoboynik M, Borazanci E, Falchook G, Molife LR, Pant S, Dean E, Pelosof L, Jones S, Rubino C, McCulloch W, Zhukova-Harrill V, Kemble G, O’Farrell M, Burris HA III. First-in-human study of the first-in-class fatty acid synthase (FASN) inhibitor, TVB-2640 as monotherapy or in combination – final results of dose escalation. Mol Cancer Ther 14(12S), 2015. e-Pub 2015.
- Infante JR, Naing A, Papadopoulos KP, Autio KA, Ott PA, Wong DJ, Falchook GS, Patel M, Pant S, Whiteside M, Bendell JC, Bauer TM, Janku F, Javle M, Colen R, Tannir N, Oft M. PEGylated human IL-10 (AM0010) in advanced solid tumors. AACR-NCI-EORTC International Conference: Mol Cancer Ther 14(12), 2015. e-Pub 2015.
- Zhou X, Nemunaitis J, Pant S, Bauer TM, Patel M, Sarantopoulos J, Lockhart AC, Goodman D, Zhang B, Dansky Ullmann C, Mould DR, Venkatakrishnan K. Effects of alisertib (MLN8237), an investigational Aurora A kinase inhibitor (AAKi), on the QTc interval in patients (pts) with advanced malignancies. The European Cancer Congress 2015 Scientific Programme. e-Pub 2015.
- Arkenau HT, Voskoboynik M, Infante J, Brenner A, Patel M, Borazanci E, Falchook G, Molife LR, Pant S, Dean E, Pelosof L, Jones S, Rubino C, McCulloch W, Zhukova-Harrill V, Kemble G, O'Farrell M, Burris H. Evidence of activity of a new mechanism of action (MoA): A first-in-human study of the first-in-class fatty acid synthase (FASN) inhibitor, TVB-2640, as monotherapy or in combination. The European Cancer Congress 2015 Scientific Programme. e-Pub 2015.
- Scientific Programme TECC. Effects of rifampin, a strong metabolic enzyme inducer, on the pharmacokinetics (PK) of alisertib (MLN8237), an investigational Aurora A kinase inhibitor (AAKi), in patients with advanced solid tumors or lymphomas. Zhou X, Pant S, Sarantopoulos J, Patel M, Nemunaitis J, Lockhart AC, Zhang B, Bargfrede M, Muehler A, Venkatakrishnan K. e-Pub 2015.
- Disis ML, Patel M, Pant S, Hamilton EP, Lockhart AC, Kelly K, Thaddeus-Beck J, Gordon M, Weiss GL, Ejadi S, Taylor MH, Chin K, Cuillerot JM, Von Heydebreck A, Gulley Avelumab JA. Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with recurrent or refractory ovarian cancer: A phase Ib trial reporting safety and clinical activity. The European Cancer Congress 2015 Scientific Programme. e-Pub 2015.
- Voss M, Gordon MS, Mita M, Rini B, Makker V, Macarulla T, Smith D, Kwak EL, Cervantes A, Puzanov I, Pili R, Wang D, Jalal S, Pant S, Patel M, Neuwirth R, Zohren F, Infante J. Phase I study of investigational oral mTORC1/2 inhibitor MLN0128: Expansion phase in patients with renal, endometrial, or bladder cancer. The European Cancer Congress 2015 Scientific Programme. e-Pub 2015.
- Tolaney SM, Beeram M, Beck JT, Conlin AK, Dees EC, Dickler MN, Helsten TL, Conkling PR, Edenfield WJ, Richards DA, Turner PK, Cai N, Chan EM, Pant S, Becerra C, Kalinsky K, Puhalla S, Rexer BN, Burris HA, Goetz MP. A phase Ib study of abemaciclib with therapies for metastatic breast cancer. J Clin Oncol, 2015 ASCO Annual Meeting Proceedings 33(15S), 2015. e-Pub 2015.
- Moore KN, Varghese AM, Hyman DM, Callies S, Lin J, Wacheck V, Pant S, Bauer TM, Bendell JC. A phase I, first-in-human dose study of the dual PI3K/mTOR inhibitor LY3023414 (LY) in patients (pts) with advanced cancer. J Clin Oncol, 2015 ASCO Annual Meeting Proceedings 33(15), 2015. e-Pub 2015.
- Pant S, Patel MR, Kurkjian C, Hemphill MB, Flores MRC, Thompson DS, Bendell JC. A phase II study of the c-Met inhibitor tivantinib (tiv) in combination with FOLFOX for the treatment of patients (pts) with previously untreated metastatic adenocarcinoma of the distal esophagus, gastroesophageal (GE) junction, or stomach. J Clin Oncol, 2015 ASCO Annual Meeting Proceedings 33(15), 2015. e-Pub 2015.
- Infante JR, Naing A, Papadopoulos KP, Autio KA, Ott PA, Wong DJL, Falchook GS, Patel MR, Pant S, Whiteside M, Bendell JC, Bauer TM, Janku F, Javle MM, Hong DS, Oft M. A first-in-human dose escalation study of PEGylated recombinant human IL-10 (AM0010) in advanced solid tumors. J Clin Oncol, 2015 ASCO Annual Meeting Proceedings 33(15S), 2015. e-Pub 2015.
- Disis ML, Patel MR, Pant S, Infante JR, Lockhart C, Kelly K, Beck JT, Gordon MS, Weiss GL, Ejadi S, Taylor MH, von Heydebreck A, Chin KM, J-M C, Gulley JL. Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with previously treated, recurrent or refractory ovarian cancer: A phase Ib, open-label expansion trial. J Clin Oncol, 2015 ASCO Annual Meeting Proceedings 33(15S), 2015. e-Pub 2015.
- Zhou X, Nemunaitis J, Pant S, Bauer T, Lockhart A, Patel M Zhang B, Kelly V, Ullmann CD, Bargfrede M Venkatakrishnan K. The effect of esomeprazole, a proton pump inhibitor, on the pharmacokinetics of the investigational Aurora A kinase inhibitor alisertib (MLN8237) in patients with advanced solid tumors or lymphomas. Proceedings of the 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Eur J Cancer 50(6), 2014. e-Pub 2014.
- Sarantopoulos J, Goel S, Chung V, Munster P, Pant S, Patel M, Infante J, Tawbi H, Becerra C, Bruce J, Kabbinavar F, Kaufman H, Lockhart AC, Tan E, Yang S, Diallo M, Scott J, Sharma S. Randomized, phase 1 crossover study assessing the bioequivalence of tablet and capsule formulations of dovitinib (TKI258). AACR Annual Meeting 2014 Proceedings, Cancer Res 74(19), 2014. e-Pub 2014.
- Osama Khawandanah M, Kurkjian C, Penaroza S, Arnold C, Herman TS, Talbert M, Postier R, Pant S. Utility of 18F-flourodeoxyglucose positron emission tomography (FDG-PET) to predict resectability after neoadjuvant therapy in patients with unresectable pancreatic cancer on CT scans. J Clin Oncol, Proceedings of the 2014 ASCO Gastrointestinal Cancers Symposium 32(3S), 2014. e-Pub 2014.
- Pant S, Hart LL, Bendell JC, Infante JR, Fields Jones S, Mohyuddin A, Murphy P, j P, Charles Penley W, Shelton Thompson D, Burris HA. Phase I study of the HSP90 inhibitor AUY922 in combination with capecitabine as treatment for patients with advanced solid tumors. J Clin Oncol, 2013 ASCO Annual Meeting 31(15S), 2013. e-Pub 2013.
- Wirth LJ, Dakhil SR, Kornek G, Axelrod R, Adkins D, Pant S, O’Brien PE, Debruyne PR, Oliner KS, Dong J, Bach BA. Partner: A randomized phase II study of docetaxel/cisplatin (doc/cis) chemotherapy with or without panitumumab (pmab) as first-line treatment (tx) for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). J Clin Oncol, Proceedings of the 2013 ASCO Annual Meeting 31(15S), 2013. e-Pub 2013.
- Martin LK, Wei L, Van Loon K, Lyer RV, Pant S, Fogelman DR, Ko AH, Bekaii-Saab TS. Treatment-related hypertension (HTN) as a predictive biomarker for clinical outcomes in patients (pts) with advanced pancreas cancer (APCA) treated with bevacizumab (B): A pooled analysis of four prospective clinical trials. J Clin Oncol, 2013 ASCO Gastrointestinal Cancers Symposium 31(4S), 2013. e-Pub 2013.
- Bendell J, Hart LL, Pant S, Infante JR, Fields Jones S, Mohyuddin A, Murphy P, Patton J, Penley WC, Shelton Thompson D, Burris HA. Phase I study of the HSP90 inhibitor AUY922 in combination with capecitabine as treatment for patients with advanced solid tumors. J Clin Oncol, 2013 ASCO Gastrointestinal Cancers Symposium 31(4S), 2013. e-Pub 2013.
- Kurkjian C, Pant S, Burris HA, Bendell JC, Fields Jones S, Moore KN, Moreno O, Mass RD, Infante JR. ME-143, a novel inhibitor of tumor-specific NADH oxidase (tNOX): Results from a first-in-human phase I study. J Clin Oncol, 2012 ASCO Annual Meeting 30(15S), 2012. e-Pub 2012.
- Pant S, Fields Jones S, Kurkjian C, Infante JR, Moore KN, Burris HA, McMeeking S, Kursar JD, Zamek-Gliszczynski M, Jones E, Yuen E, Chan EM, Bendell JC. A first-in-human phase I study of the oral fNotch inhibitor LY900009 in patients with advanced cancer. J Clin Oncol, 2012 ASCO Annual Meeting 30(15S), 2012. e-Pub 2012.
- Srour SA, Machiorlatti M, Bhutta U, Pierson N, Cherry MA, Pant S, Thompson D, Kurkjian C. Acute myeloid leukemia: comparison of epidemiology and treatment outcomes between insured and uninsured patients. J Clin Oncol, 2012 ASCO Annual Meeting 30(15S). e-Pub 2012.
- H-T A, Infante JR, Pant S, Burris HA, McMeekin DS, Gibbons J, Harrow K, Liang C, Ramsey S, Bendell JC. The PI3K/mTOR inhibitor BEZ235 given twice daily for the treatment of patients (pts) with advanced solid tumors. J Clin Oncol, 2012 ASCO Annual Meeting 30(15S), 2012. e-Pub 2012.
- Moore KN, Fields Jones S, Kurkjian C, H-T A, Infante JR, Pant S, Burris HA, McMeekin DS, GibbonsJ, Harrow K, Liang C, Ramsey S, Bendell JC. Phase I, first-in-human trial of an oral VEGFR tyrosine kinase inhibitor (TKI) x-82 in patients (pts) with advanced solid tumors. J Clin Oncol, 2012 ASCO Annual Meeting 30(15S), 2012. e-Pub 2012.
- Butt S, Akl P, Bhardwaj H, Srour SA, Dunn T, Pant S, Cherry MH. Patients with FLT3 negative acute myeloid leukemia and normal cytogenetic who have the combination mutations (NPM1-/CEBPA-) have better survival than patients who have the combination mutations (NPM1+/CEBPA+). Blood, ASH Annual Meeting 118(21), 2011. e-Pub 2011.
- Hopps S, Borders E, Medina P Moorman M, Webb R, Kurkjian C, Pant S. Incidence and risk factors of cetuximab-induced hypersensitivity infusion reactions (HIRs). J Clin Oncol, 2011 ASCO Annual Meeting 29(15S). e-Pub 2011.
- Camacho LH, Pant S, Saleh MN, Abbadessa G, Kazakin J, Schwartz BE, Bendell JC. Phase 1b results of c-MET inhibitor ARQ 197 in combination with gemcitabine in a cohort of patients (pts) with advanced breast, ovarian, and uterine tumors. J Clin Oncol, 2011 ASCO Annual Meeting 29(15S), 2011. e-Pub 2011.
- Hopps S, Borders E, Medina P Moorman M, Webb R, Kurkjian C, Pant S. Incidence and risk factors of cetuximab-induced hypersensitivity infusion reactions (HIRs). J Clin Oncol, 2011 ASCO Annual Meeting 29(15S). e-Pub 2011.
- Khawandanah M, Chimpiri R, Kurkjian C, Herman TS, Qubaiah OM, Postier R, Ghabach B, Thompson D, Pant S. Factors affecting resection rate in patients undergoing neoadjuvant therapy for pancreatic cancer. J Clin Oncol, 2011 ASCO Annual Meeting 29(15S). e-Pub 2011.
- Pant S, Saleh M, Bendell J, Abbadessa G, Kazakin J, Chen C, Schwartz B, Camacho LH. Phase 1b dose escalation trial evaluating c-Met inhibitor ARQ 197 and Gemcitabine in patients (pts) with advanced solid tumors on schedules refined by in vitro mechanistic studies. Book of the 35th European Society of Medical Oncology (ESMO) Congress, Ann Oncol 21(8S), 2010. e-Pub 2010.
- Pant S, Hostetter G, Armstrong B, Bittner M, Shack S, Savage S, Weiss GJ, Ozer H, Ramanathan R. Use of independent genome-wide assays to discover HOXA signature in colon and rectal cancers and validate a role in tumorigenesis. J Clin Oncol, 2009 ASCO Annual Meeting Proceedings 27(15S). e-Pub 2009.
- Pant S, Armstrong B, Hostetter G, Weiss GJ, Ozer H, Ramanathan R. Colon and rectal cancer gene expression profiles: Results from the analysis of samples in Expression Project for Oncology (expO) database. ASCO Meeting Library, 2009 Gastrointestinal Cancers Symposium. e-Pub 2009.
- Pant S, Hamadani SM, Crilley P, Szer J, Dodds AJ, Stevenson DE, Phillips G, Elder P, Nivison-Smith I, Avalos B, Penza S, Topolsky D, Sobecks R, Kalaycio M, Bolwell BJ, Copelan E. Incidence of late failure following myeloablative conditioning with BuCy2 and matched sibling allogeneic stem cell transplantation for acute myeloid leukemia. Blood 112(11), 2008. e-Pub 2008.
- Pant S, Crilley PA, Dodds AJ, Szer J, Bolwell BJ, Elder P, Styler M, Kalaycio M, Sobecks R, Nivison-Smith I, Avalos BR, Copelan EA. Long-term follow-up of treatment for acute myeloid leukemia with allogeneic hematopoetic cell transplantation using BuCy2 as preparation. Blood 108(11), 2006. e-Pub 2006.
- Kojouri K, Pant S, Kamble R, Sylvester-Kohrt N, Selby GB, Ozer H, Kharfan-Dabaja MA. Significance of elevated serum lactate dehydrogenase (LDH) in patients undergoing salvage autologous bone marrow/peripheral stem cell transplantation (BM/PSCT) for relapsed/refractory Hodgkin’s lymphoma (R/R-HL). J Clin Oncol, 2005 ASCO Annual Meeting Proceedings 23(16S), 2005. e-Pub 2005.
- Pant S, Venkatappa S, Sethi S, Lightfoot S, Tfayli A, Ozer H. Male breast cancer: molecular pathology and demographics of a case series. J Clin Oncol, 2004 ASCO Annual Meeting Proceedings 22(14S), 2004. e-Pub 2004.
Book Chapters
- Lee, MS, Pant, S. Targeted Therapies for Pancreatic Cancer, 67-95, 2023.
- Pant, S, Surana, R. Early drug development in pancreatic cancer, 291-297, 2022.
- Surana, R, Pant, S. Immunotherapy in Gastrointestinal Malignancies, 259-272, 2021.
Books (edited and written)
- Pant, S. Pancreatic Cancer, 2023.
- Karp DD, Falchook GS, Lim J, Pant S. Handbook of Targeted Cancer Therapy and Immunotherapy. Ed(s) 2. Wolters Kluwer, 2018.
Letters to the Editor
- Yousef, M, Yousef, A, Hurd, MW, Balachandran Pillai, A, Chowdhury, S, Snyder, RA, Knafl, M, Lewis, RL, Roy, PM, Fanaeian, M, Albarouki, S, Castelnovo, LF, Peterson, J, Smaglo, BG, Wolff, RA, Pant, S, Willis, JA, Huey, RW, Overman, MJ, Tzeng, CW, Kim, M, Ikoma, N, Maxwell, JE, Katz, MH, Wang, H, Maitra, A, Koay, EJ, Ludmir, EB, Chen, A, Lopez, C, Ying, H, Shen, JY, Zhao, D. KRAS mutation detection by liquid biopsy for pancreatic ductal adenocarcinoma. Journal of Hematology and Oncology 18, 2025.
Patient Reviews
CV information above last modified July 14, 2025