Stephanie S. Watowich, Ph.D.
Department of Immunology, Division of Discovery Science
About Dr. Stephanie S. Watowich
Dr. Stephanie S. Watowich is Professor and Deputy Chair in the Department of Immunology at MD Anderson Cancer Center, where she holds the Vivian L. Smith Distinguished Chair in Immunology. The overarching focus of Dr. Watowich’s research is to understand molecular mechanisms that regulate innate immune cell generation and function in cancer and inflammation, with the goal of using this knowledge to advance new cancer immunotherapies. Dr. Watowich’s laboratory has been a leader in defining roles for the cytokine-activated signal transducer and activator of transcription (STAT) factors in innate immune cells, particularly STAT3 in myeloid and dendritic cells (DCs). Her research projects center on delineating how cytokines and STAT3 regulate the function of antigen-presenting cells in tumors, advancing use of a novel type 1 conventional dendritic cell (cDC1) vaccine in immunotherapy-refractory cancers, and understanding how STAT3 signaling protects the hematopoietic system. Her laboratory recently pioneered novel animal models of immune checkpoint inhibitor (ICI) -associated colitis, which are used to investigate innate immune subsets and fecal microbiome components that influence therapeutic response to ICI and development of ICI colitis. In addition, Dr. Watowich is committed to providing optimal career opportunities for the next generation of scientists through leadership of innovative research training programs at The University of Texas MD Anderson Cancer Center. Dr. Watowich has received numerous honors and awards including The William Randolph Hearst Foundation Faculty Achievement Award in Education, MD Anderson (2009), induction into the UT Kenneth I. Shine Academy of Health Science Education (2010), the John P. McGovern Outstanding Teacher Award (2010), and the President’s Recognition of Faculty Excellence for Education and Mentorship Advancement (2022). In 2023, she was recognized by her alma mater with the Carleton College Alumni Distinguished Service Award.
Present Title & Affiliation
Dual/Joint/Adjunct Appointment
Vivian L. Smith Distinguished Chair in Immunology, Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX
Deputy Department Chair, Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Professor, Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX
Member, Graduate Faculty, MD Anderson UTHealth Graduate School, Houston, TX
Education & Training
Degree-Granting Education
| 1990 | Northwestern University, Evanston, Illinois, US, Biochemistry, Molecular Biology and Cell Biology, PhD |
| 1983 | Carleton College, Northfield, Minnesota, US, Biology, BA |
Postgraduate Training
| 1990-1995 | Postdoctoral Fellow, Cellular and Molecular Biology, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts |
Experience & Service
Administrative Appointments/Responsibilities
Co-Director, CATALYST Summer Training Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2023 - Present
Deputy Department Chair, Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - Present
Immunology Lead, PRIME TR, The University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - Present
Co-Chair, Immunology Cluster, Gulf Coast Consortia, Houston, TX, 2020 - 2022
Co-Director, Center for Inflammation and Cancer (CIC), The University of Texas MD Anderson Cancer Center, 2010 - Present
Director, Program in Immunology, MD Anderson UTHealth Graduate School, Houston, TX, 2004 - 2010
Other Professional Positions
Research Assistant, University of Chicago, Chicago, IL, 1983 - 1985
Extramural Institutional Committee Activities
Member, Faculty Recruitment Panel, The University of Texas MD Anderson Cancer Center, 2023 - Present
Member, IOTOX Working Group, The University of Texas MD Anderson Cancer Center, 2023 - 2024
Chair, Faculty Search Committee, Department of Immunology, The University of Texas MD Anderson Cancer Center, 2022 - Present
Internal Advisory Board Member, Ovarian SPORE, MD Anderson, The University of Texas MD Anderson Cancer Center, 2022 - Present
Co-Director of the Developmental Research Program (DRP)/Career Enhancement Program (CEP), Melanoma SPORE, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Faculty Senate Executive Committee, The University of Texas MD Anderson Cancer Center, 2021 - 2023
Member, Research Enablement, The University of Texas MD Anderson Cancer Center, 2021 - 2022
Member, Tenure/Tenure Track Review Committee, The University of Texas MD Anderson Cancer Center, 2021
Member, Faculty Achievement Awards Committee, The University of Texas MD Anderson Cancer Center, 2021
Internal Advisory Board Member, P01 Program, Modulation of the Central Nervous System (CNS) Innate Immune Interactions within Glioma, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Member, Program in Cancer Biology Steering Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Member, Faculty Search Committee, Department of Genetics, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Internal Advisory Board Member, Flow Cytometry and Cellular Imaging Core Facility, The University of Texas MD Anderson Cancer Center, 2018 - Present
Member, Mike Hogg Lecture Selection Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2022
Member, Promotion and Tenure Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2021
Member, Internal Award Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2021
Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2017 - 2023
Member, Faculty Search Committee, Department of Immunology, The University of Texas MD Anderson Cancer Center, 2014 - 2022
Team Lead, Trainee Recruitment, The University of Texas MD Anderson Cancer Center Strategic Plan, The University of Texas MD Anderson Cancer Center, 2014 - 2015
President, Academy for Health Science Education (AHSE), The University of Texas MD Anderson Cancer Center, 2012 - 2013
Judge, Division of Internal Medicine Cyrus Awards, The University of Texas MD Anderson Cancer Center, 2012
Chair (11/30/12), Advances in Oncology Institutional Grand Rounds, The University of Texas MD Anderson Cancer Center, 2012
Member and Past-Chair, Graduate Education Committee, The University of Texas MD Anderson Cancer Center, 2011 - 2012
Member, The Charles A. LeMaistre Outstanding Achievement Award in Cancer Selection Committee, The University of Texas MD Anderson Cancer Center, 2011
Member, Dean Search Committee, The University of Texas MD Anderson Cancer Center, 2011
Member, Academy for Health Science Education, The University of Texas MD Anderson Cancer Center, 2010 - Present
Member, Program in Immunology Steering Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2010 - 2013
Member, Faculty Search Committee, Department of Infectious Diseases, The University of Texas MD Anderson Cancer Center, 2010 - 2011
Member, Faculty Achievement Awards Committee, The University of Texas MD Anderson Cancer Center, 2010
Member, Scientific Review Committee for Basic Research Projects, The University of Texas MD Anderson Cancer Center, 2009 - 2012
Member, Odyssey Program Advisory Committee, The University of Texas MD Anderson Cancer Center, 2009 - 2012
Member, Scientific Review Committee for American Cancer Society (ACS) Institutional Research Grants (IRGs), The University of Texas MD Anderson Cancer Center, 2009 - 2012
Chair, Graduate Education Committee, The University of Texas MD Anderson Cancer Center, 2009 - 2011
Member, Committee on Faculty Awards, The University of Texas MD Anderson Cancer Center, 2009 - 2011
Member, Faculty Advisory Committee, South Campus Animal Facility, The University of Texas MD Anderson Cancer Center, 2008 - Present
Member, John H Blaffer Lecture Seminar Series Steering Committee, The University of Texas MD Anderson Cancer Center, 2008 - 2020
Member, Strategic Planning for Research Space Development-Transportation-People and Specimens Committee, The University of Texas MD Anderson Cancer Center, 2008 - 2011
Member, Faculty Health Committee, The University of Texas MD Anderson Cancer Center, 2008 - 2010
Vice-Chair, Graduate Education Committee, The University of Texas MD Anderson Cancer Center, 2007 - 2009
Member, Executive Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2007 - 2009
Chair, Program Coordinating Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2007 - 2009
Ad-hoc Reviewer, Center for Targeted Therapy (CTT) Disease-Specific Grant Program, The University of Texas MD Anderson Cancer Center, 2007 - 2008
Member, Alfred G Knudson Jr Award Committee for Outstanding PhD Dissertation, The University of Texas MD Anderson Cancer Center, 2007
Member, Education Retreat Committee, The University of Texas MD Anderson Cancer Center, 2007
Member, Ad Hoc Membership Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2007
Member, Hearst Foundation Innovative Research and Educational Award Review Committee, Genes and Development Program, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2007
Member, Faculty Search Committee, Department of Biochemistry, The University of Texas MD Anderson Cancer Center, 2005
Member, Alfred G. Knudson, Jr. Award Committee for Outstanding PhD Dissertation, The University of Texas MD Anderson Cancer Center, 2005
Member, Program Coordinating Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2004 - 2010
Member, Institutional Animal Care and Use Committee (IACUC), The University of Texas MD Anderson Cancer Center, 2003 - 2005
Member, Program in Immunology Steering Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2001 - 2004
Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2001 - 2003
Member, Study Section Review Committee for Basic Research Projects, The University of Texas MD Anderson Cancer Center, 2000 - 2003
Member, Intellectual Property Oversight Committee, The University of Texas MD Anderson Cancer Center, 2000 - 2002
Chair, Academic Standards Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2000 - 2001
Member, Executive Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 2000 - 2001
Member, Odyssey Scholarship Advisory Committee, The University of Texas MD Anderson Cancer Center, 1999 - 2005
Member, Faculty Advisory Committee for the New Institutional Grants Program, The University of Texas MD Anderson Cancer Center, 1999
Member, Academic Standards Committee, MD Anderson UTHealth Graduate School, The University of Texas MD Anderson Cancer Center, 1998 - 2000
Editorial Activities
Member of Editorial Review Board, Journal of Immunology, 2014 - 2018
Member of Editorial Review Board, Genes and Immunity, 2013 - 2018
Member of Editorial Review Board, Journal of Interferon and Cytokine Research, 1998 - 2001
Honors & Awards
| 2026 | AAAS Fellow, American Association For The Advancement of Science |
| 2023 | Exceptional Service Award, Carleton College Alumni Association |
| 2021 | President's Recognition of Faculty Excellence in Education & Mentorship Advancement, The University of Texas MD Anderson Cancer Center |
| 2020 | Robert M. Chamberlain Distinguished Mentor Award, Finalist, The University of Texas MD Anderson Cancer Center |
| 2020 | President’s Recognition of Faculty Excellence in Education & Mentorship Advancement, The University of Texas MD Anderson Cancer Center |
| 2019 | International Cytokine and Interferon Society Travel Award, International Cytokine and Interferon Society |
| 2019 | Harriet Tischler Memorial Lecturer, Dana Farber Cancer Center |
| 2016 | AAI Travel Award, American Association of Immunologists (AAI) |
| 2016 | Reappointment with Commendation, MD Anderson UTHealth Graduate School |
| 2013 | Nominee for The University of Texas Regents' Outstanding Teaching Award, The University of Texas MD Anderson Cancer Center |
| 2012 - Present | Distinguished Teaching Professor, The University of Texas MD Anderson Cancer Center |
| 2012 | Nominee for The University of Texas Regents' Outstanding Teaching Award, The University of Texas MD Anderson Cancer Center |
| 2010 - Present | Elected Member, The University of Texas Academy of Health Science Education |
| 2010 | John P. McGovern Outstanding Teacher Award, MD Anderson UTHealth Graduate School |
| 2009 | The William Randolph Hearst Foundation Faculty Achievement Award in Education, The University of Texas MD Anderson Cancer Center |
| 2008 | Faculty Educator of the Month, The University of Texas MD Anderson Cancer Center |
| 2005 | Reappointment with Highest Commendation, MD Anderson UTHealth Graduate School |
| 1999 | Deans Excellence Award, MD Anderson UTHealth Graduate School |
| 1991 - 1994 | Postdoctoral Fellowship, American Cancer Society (ACS) |
| 1990 - 1991 | Postdoctoral Fellowship, Anna Fuller Fund |
| 1989 - 1990 | Carcinogenesis Training Grant Fellowship, National Cancer Institute (NCI), National Institutes of Health (NIH) |
| 1987 - 1989 | Cellular and Molecular Biology Training Grant Fellowship, National Research Service Award (NRSA), National Institutes of Health (NIH) |
| 1986 - 1987 | Graduate Training Program in Basic Research Fellowship, United States of America, Army |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2024. Mouse models of ICI colitis. Invited. Houston, Texas, US.
- 2024. Studies in myeloid inflammation: informing our understanding of tumor immunity and off-target toxicities. Invited. Houston, Texas, US.
- 2024. Studies in myeloid inflammation: informing our understanding of tumor immunity and off-target toxicities. Invited. Houston, Texas, US.
- 2024. Dendritic cell therapy: vaccines to enhance anti-tumor immunity. Invited. Houston, Texas, US.
- 2023. Understanding host-microbiome communication affecting checkpoint blockade response and toxicity. Invited. Houston, TX, US.
- 2022. New animal models for checkpoint blockade intestinal irAEs. Invited. Houston, Texas, US.
- 2021. Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration. Invited. Houston, Texas, US.
- 2021. Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration. Invited. Houston, TX, US.
- 2020. Dendritic cells, vaccines, and anti-tumor immunity. Invited. Houston, TX, US.
- 2020. Models of immune-related adverse events and new cellular therapies with checkpoint blockade. Invited. Houston, TX, US.
- 2020. Models of immune-related adverse events with checkpoint blockade. Invited. Houston, TX, US.
- 2019. Fundamentals of immunology and advancing immunotherapy. Invited. Houston, TX, US.
- 2019. Dendritic cell mediated anti-tumor immunity. Invited. Houston, TX, US.
- 2019. Dendritic cell mediated anti-tumor immunity. Invited. Houston, TX, US.
- 2019. Fundamentals of immunology. Invited. Houston, Texas, US.
- 2018. Fundamental studies of dendritic cells and STATs in animal models to improve cancer immunotherapy. Invited. Houston, TX, US.
- 2018. Transcriptional regulation of dendritic cell development and anti-tumor immunity. Invited. Houston, TX, US.
- 2017. Innate immune regulation by STAT3. Invited. Houston, TX, US.
- 2017. Innate immune regulation in inflammation and cancer. Invited. Galveston, Texas, US.
- 2015. STAT3, inflammation and innate immunity. Invited. Houston, TX, US.
- 2014. STAT3, inflammation and MDS. Invited. Houston, TX, US.
- 2014. Innate immune regulation by STAT-mediated transcriptional mechanisms. Invited. Houston, TX, US.
- 2012. Inflammatory and anti-inflammatory roles for STAT3 in immunity. Invited. Houston, TX, US.
- 2012. Inflammatory and anti-inflammatory roles for STAT3 in myeloid cells. Invited. Houston, TX, US.
- 2011. A STATus report on dendritic cells: critical regulators of innate and adaptive immunity. Invited. Houston, TX, US.
- 2010. Molecular mechanisms of STAT transcription factor signaling in innate and adaptive immunity. Invited. Houston, TX, US.
- 2009. Immunoregulatory roles for STAT3 and STAT5. Invited. Houston, TX, US.
- 2006. STAT3 in granulopoiesis and neutrophil function. Invited. Houston, TX, US.
- 2001. Cytokine signaling mechanisms in hematopoietic cells. Invited. Houston, TX, US.
- 2001. Cytokine regulation of blood cell development. Invited. Houston, TX, US.
- 2000. Cytokine regulation of blood cell development. Invited. Houston, TX, US.
- 1997. Molecular events in cytokine receptor activation. Invited. Houston, TX, US.
- 1996. Molecular events in cytokine receptor signaling. Invited. Galveston, Texas, US.
- 1996. Molecular events in cytokine receptor activation. Invited. Houston, TX, US.
- 1996. Molecular events in cytokine receptor signaling. Invited. Houston, TX, US.
Regional Presentations
- 2025. Type 1 dendritic cells as a novel cell therapy in cancer. Invited. FlowTex Annual Meeting. Houston, TX, US.
- 2024. Examining immune checkpoint inhibitor mediated colitis with spectral flow cytometry. Invited. FlowTex Annual Meeting. Houston, Texas, US.
- 2023. Vaccine approaches to enhance anti-tumor immunity. Invited. Vaccine Development Center of San Antonio Annual Conference. San Antonio, TX, US.
- 2021. Dendritic cell mediated anti-tumor immunity. Invited. Experimental and Developmental Therapeutics Monthly Meeting, US.
- 2016. Transcriptional regulation of innate immunity: effects in the tumor microenvironment. Invited. San Antonio, TX, US.
- 2014. A STATus report on dendritic cells: mechanisms of transcriptional control. Invited. College Station, TX, US.
- 2013. A STATus report on dendritic cells: mechanisms of transcriptional control by STATs. Invited. San Antonio, TX, US.
- 2011. Initiatives in graduate education. Panelist. The University of Texas Academy of Health Science Education 7th Annual Innovations in Health Science Education Conference. San Antonio, TX, US.
- 2007. Immunoregulatory roles for STAT3 and STAT5. Invited. The University of Texas MD Anderson Cancer Center and The University of Texas Medical Branch Joint Symposium on Immunology. Galveston, TX, US.
National Presentations
- 2025. Studies in myeloid inflammation: informing our understanding of tumor immunity and off-target toxicities. Invited. Malkin-Kraft Lecture. Chicago, Illinois, US.
- 2024. Studies in myeloid inflammation: informing our understanding of tumor immunity and off-target toxicities. Invited. NIH Chronic Inflammation Working Group. Bethesda, MD, US.
- 2023. Inflammation and cancer. Panelist. Chronic Inflammation Webinar, US.
- 2022. Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration. Invited. Philadelphia, Pennsylvania, US.
- 2021. Dendritic cell mediated anti-tumor immunity. Departments of Microbiology and Immunology. Miami, FL, US.
- 2020. Understanding and combating mechanisms of immune-related adverse events to checkpoint blockade. Invited. Models and Methods to Dissect Toxicity in Cancer Treatment, US.
- 2019. Roles for dendritic cells in inflammation, tumor immunity, and immune therapy. Invited. Microbiology and Immunology Fall Student Symposium. Winston-Salem, NC, US.
- 2019. Protective roles for STAT3 in inflammation and hematopoiesis. Invited. Harriet Tischler Memorial Lecture. Boston, MA, US.
- 2019. Assessing roles for dendritic cells in immune-related adverse events (irAEs) with checkpoint inhibitor therapy. Invited. NIH-AACR Cancer, Autoimmunity, and Immunology Conference. Bethesda, MD, US.
- 2018. Inflammation, STAT3, and hematopoiesis. Invited. Harvey F. Lodish 50th Year Reunion and Symposium. Cambridge, MA, US.
- 2018. Innate immune regulation in inflammation and cancer. Invited. Department of Immunology. Iowa City, IA, US.
- 2018. STAT3 signaling in hematopoiesis and tumor immunity. Invited. Duarte, CA, US.
- 2017. Protective roles for STAT3 in the hematopoietic system. Invited. STATs: Importance in Basic & Clinical Cancer Research. Cold Spring Harbor, NY, US.
- 2017. Transcriptional regulation of dendritic cell development and anti-tumor immunity. Invited. Departments of Microbiology and Immunology. North Chicago, IL, US.
- 2016. Innate immune regulation in inflammation and cancer. Invited. Departments of Microbiology and Immunology. North Chicago, IL, US.
- 2016. Innate immune regulation by STAT3. Invited. Cytokine JAK-STAT Signaling in Immunity and Disease. Steamboat Springs, CO, US.
- 2014. Transcriptional regulation of innate immune cell development. Invited. Department of Biology. Northfield, MN, US.
- 2013. A STATus report on dendritic cells: mechanisms of transcriptional control. Invited. Department of Immunology. Seattle, WA, US.
- 2012. A STATus report on dendritic cells: mechanisms of transcriptional control by STATs. Invited. Division of Biological Sciences. San Diego, CA, US.
- 2011. A STATus report on dendritic cells: mechanisms of transcriptional control by STATs. Invited. 2011 Annual Meeting, Society for Leukocyte Biology. Kansas City, MO, US.
- 2011. A STATus report on dendritic cells: mechanisms of transcriptional control by STATs. Invited. Molecular Mechanisms of Immune Cell Development & Function. Snowmass Village, CO, US.
- 2010. STAT signaling mechanisms and the stress of infection. Invited. Amherst, MA, US.
- 2010. STAT signaling mechanisms and the stress of infection. Invited. Department of Biochemistry, Molecular Biology, and Cell Biology Annual Retreat. Chicago, IL, US.
- 2010. Regulation of myeloid progenitor growth and neutrophil function by STAT3. Invited. Thousand Oaks, CA, US.
- 2010. Assembly of the erythropoietin receptor. Invited. Experimental Biology Meeting, American Federation for Medical Research (AFMR). Anaheim, CA, US.
- 2008. Immunoregulatory roles for STAT3 and STAT5. Invited. Bortree Lecture Series, Department of Veterinary and Biomedical Sciences. State College, PA, US.
- 2005. STAT function in neutrophils. Invited. Departments of Microbiology and Immunology. Ithaca, NY, US.
- 2004. Epo and G-CSF signaling through STAT pathways. Invited. Thousand Oaks, CA, US.
- 2003. Molecular control of blood cell development - from basic research to clinical significance. Invited. Department of Biology. Northfield, MN, US.
- 2003. Basic science of erythropoietin and the erythropoietin receptor. Invited. Molecular Experts Advisory Board Meeting. NY, NY, US.
- 2002. Cytokine signaling mechanisms in hematopoietic cells. Invited. Buffalo, NY, US.
- 1993. Assembly of the erythropoietin receptor. Invited. Boston, MA, US.
- 1992. Dimerization and activation of the erythropoietin receptor. Invited. Gordon Research Conferences, Animal Cells and Viruses. New London, NH, US.
International Presentations
- 2026. Contributions of the microbiota to intestinal immune-related adverse events with ICI treatment. Invited. 7th International Conference on Cytokines in Cancer. Philadelphia, US.
- 2024. Understanding host-microbiome communication affecting checkpoint blockade response and toxicity. Invited. 6th International Conference on Cytokine Signaling in Cancer. Loutraki, GR.
- 2023. Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration. Invited. 5th International Conference on Cytokine Signaling in Cancer. Kos, GR.
- 2023. Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration. Invited. 6th iTOX Symposium. Paris, FR.
- 2022. Mechanisms of immune toxicity in checkpoint blockade therapy. Invited. MD Anderson - Weizmann Institute Symposium. Rehovot, IL.
- 2022. Mechanisms of immune toxicity in checkpoint blockade therapy. Invited. 4th International Conference on Cytokine Signaling in Cancer. Chania, GR.
- 2019. Assessing roles for dendritic cells in immune-related adverse events (irAEs) with checkpoint inhibitor therapy. Invited. 3rd International Conference on Cytokine Signaling in Cancer. Rhodes, GR.
- 2018. Innate immune regulation in inflammation and cancer. Invited. Adelaide, AU.
- 2017. Innate immune regulation in inflammation and cancer. Invited. 2nd International Conference on Cytokine Signaling in Cancer. Heraklion, GR.
- 2016. Transcriptional regulation of dendritic cell development and anti-tumor immunity. Invited. Melbourne, AU.
- 2014. Protective roles for STAT3 in inflammation and hematopoiesis. Invited. Yantai, CN.
- 2013. Transcriptional regulation of dendritic cell development. Invited. JAK/STAT Signalling: Model Systems and Beyond. Nottingham, GB.
- 2012. Transcriptional control of dendritic cell development. Invited. Diversity and Plasticity of DCs. Paris, FR.
- 2012. Regulation of dendritic cell development by STATs. Invited. Ken Shortman 75th Birthday Symposium. Parkville, AU.
- 2011. Regulation of dendritic cell development by STATs. Invited. 3rd International Workshop: Plasmacytoid Dendritic Cells and Immune Responses. Paris, FR.
- 2011. A STATus report on plasmacytoid dendritic cell development. Invited. Shanghai, CN.
- 2008. Immunoregulatory roles for STAT3 and STAT5. Invited. The Institute of Molecular and Cellular Biosciences. Tokyo, JP.
- 2008. Immunoregulatory roles for STAT3 and STAT5. Invited. Graduate School of Medicine. Tokyo, JP.
- 2005. Cytokine signaling in myeloid cells: role for STAT3 in granulopoiesis and neutrophil function. Invited. Barossa Valley, AU.
- 2005. Cytokine signaling in myeloid cells: role for STAT3 in granulopoiesis and neutrophil function. Invited. Melbourne, AU.
Formal Peers
- 2019. Fundamentals of immunology. Invited. Houston, TX, US.
Selected Publications
Peer-Reviewed Articles
- Patel B, Zheng X, Kahn LM, Schneider SM, Pineda JE, Riba MN, Ouchen K, Meril S, Nash AP, Wang J, Watowich SS. STAT3 mediates an inflammation-induced microbial defense response and regulates pathogen control and clearance by macrophages. J Immunol, 2025. e-Pub 2025. PMID: 41216965.
- Baruch EN, Gleber-Netto FO, Nagarajan P, Rao X, Akhter S, Eichwald T, Xie T, Balood M, Adewale A, Naara S, Sathishkumar HN, Islam S, McCarthy W, Mattson BJ, Ferrarotto R, Wong MK, Davies MA, Jindal S, Basu S, Roversi K, Nikpoor AR, Ahmadi M, Ahmadi A, Harwood C, Leigh I, Gong D, Tallon de Lara P, Tao DL, Davidson TM, Ajami NJ, Futreal A, Rai K, Kochat V, Castillo M, Gunaratne P, Goepfert RP, Hernandez SD, Khushalani NI, Wang J, Watowich SS, Calin GA, Migden MR, Yuan M, Liu N, Ye Y, Hwang WL, Vermeer PD, D'Silva NJ, Bunimovich YL, Yaniv D, Burks JK, Gomez J, Dougherty PM, Tsai KY, Allison JP, Sharma P, Wargo JA, Myers JN, Talbot S, Gross ND, Amit M. Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy. Nature 646(8084):462-473, 2025. e-Pub 2025. PMID: 40836096.
- Wei Y, Liu M, Yen EY, Yao J, Xun Z, Nguyen PT, Wang X, Yang Z, Yousef A, Pan D, Jin Y, Li CF, Theardy MS, Park J, Cai Y, Takeda M, Vasquez M, Park EM, Peng DH, Zhou Y, Zhao H, Heffernan TP, Viale A, Wang H, Watowich SS, Liang H, Zhao D, DePinho RA, Yao W, Ying H. KRAS Inhibition Activates an Actionable CD24 "Don't Eat Me" Signal in Pancreatic Cancer. Cancer Res 85(23):4825-4838, 2025. e-Pub 2025. PMID: 40966362.
- Schalck, A, Tran, TM, Li, J, Sei, E, Bai, S, Hu, M, Lin, J, Bright, SJ, Reddick, S, Yang, F, Batra, H, Contreras, A, Raso, G, Stauder, MC, Hoffman, K, Reddy, JP, Nead, KT, Smith, B, Sawakuchi, GO, Woodward, W, Watowich, SS, Litton, J, Bedrosian, I, Mittendorf, EA, Le-Petross, H, Navin, N, Shaitelman, SF. The impact of breast radiotherapy on the tumor genome and immune ecosystem. Cell Reports 44(5), 2025. e-Pub 2025. PMID: 40378044.
- Ishikawa, C, Barreyro, L, Sampson, AM, Hueneman, K, Choi, K, Philbrook, SY, Choi, I, Bolanos, LC, Wunderlich, M, Volk, AG, Watowich, SS, Greis, KD, Starczynowski, DT. Ubiquitin-conjugating enzyme UBE2N modulates proteostasis in immunoproteasome-positive acute myeloid leukemia. Journal of Clinical Investigation 135(10), 2025. e-Pub 2025. PMID: 40371639.
- Yang, Y, Zhou, Y, Wang, J, Zhou, Y, Watowich, SS, Kleinerman, ES. CD103+ cDC1 Dendritic Cell Vaccine Therapy for Osteosarcoma Lung Metastases. Cancers 16(19):3251, 2024. e-Pub 2024. PMID: 39409873.
- Mahadevan KK, Dyevoich AM, Chen Y, Li B, Sugimoto H, Sockwell AM, McAndrews KM, Wang H, Shalapour S, Watowich SS, Kalluri R. Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer. Science 384(6703), 2024. e-Pub 2024. PMID: 36945457.
- Mahadevan KK, Dyevoich AM, Chen Y, Li B, Sugimoto H, Sockwell AM, McAndrews KM, Sthanam LK, Wang H, Shalapour S, Watowich SS, Kalluri R. Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer. Science 384(6703):eadh4567, 2024. e-Pub 2024. PMID: 38935717.
- Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Schneider SM, Tang X, Raso MG, Jeter CR, Zal T, Clise-Dwyer K, Keyomarsi K, Giancotti FG, Colla S, Watowich SS. STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response. Leukemia 38(5):1143-1155, 2024. e-Pub 2024. PMID: 38467768.
- Lulla AR, Akli S, Karakas C, Caruso JA, Warma LD, Fowlkes NW, Rao X, Wang J, Hunt KK, Watowich SS, Keyomarsi K. Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis. Mol Cancer Ther 23(4):492-506, 2024. e-Pub 2024. PMID: 37796181.
- Baruch EN, Nagarajan P, Gleber-Netto FO, Rao X, Xie T, Akhter S, Adewale A, Shajedul I, Mattson BJ, Ferrarotto R, Wong MK, Davies MA, Jindal S, Basu S, Harwood C, Leigh I, Ajami N, Futreal A, Castillo M, Gunaratne P, Goepfert RP, Khushalani N, Wang J, Watowich S, Calin GA, Migden MR, Vermeer P, D'Silva N, Yaniv D, Burks JK, Gomez J, Dougherty PM, Tsai KY, Allison JP, Sharma P, Wargo J, Myers JN, Gross ND, Amit M. Inflammation induced by tumor-associated nerves promotes resistance to anti-PD-1 therapy in cancer patients and is targetable by interleukin-6 blockade. Res Sq, 2023. e-Pub 2023. PMID: 37503252.
- Halsey TM, Thomas AS, Hayase T, Ma W, Abu-Sbeih H, Sun B, Parra ER, Jiang ZD, DuPont HL, Sanchez C, El-Himri R, Brown A, Flores I, McDaniel L, Ortega Turrubiates M, Hensel M, Pham D, Watowich SS, Hayase E, Chang CC, Jenq RR, Wang Y. Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis. Sci Transl Med 15(700):eabq4006, 2023. e-Pub 2023. PMID: 37315113.
- Park JS, Gazzaniga FS, Wu M, Luthens AK, Gillis J, Zheng W, LaFleur MW, Johnson SB, Morad G, Park EM, Zhou Y, Watowich SS, Wargo JA, Freeman GJ, Kasper DL, Sharpe AH. Targeting PD-L2–RGMb overcomes microbiome-related immunotherapy resistance. Nature 617(7960):377-385, 2023. e-Pub 2023. PMID: 37138075.
- Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Tang X, Raso MG, Zal T, Clise-Dwyer K, Giancotti FG, Colla S, Watowich SS. STAT3 protects HSCs from intrinsic interferon signaling and loss of long-term blood-forming activity. bioRxiv, 2023. e-Pub 2023. PMID: 36798265.
- Zhou Y, Medik YB, Patel B, Zamler DB, Chen S, Chapman T, Schneider S, Park EM, Babcock RL, Chrisikos TT, Kahn LM, Dyevoich AM, Pineda JE, Wong MC, Mishra AK, Cass SH, Cogdill AP, Johnson DH, Johnson SB, Wani K, Ledesma DA, Hudgens CW, Wang J, Wadud Khan MA, Peterson CB, Joon AY, Peng W, Li HS, Arora R, Tang X, Raso MG, Zhang X, Foo WC, Tetzlaff MT, Diehl GE, Clise-Dwyer K, Whitley EM, Gubin MM, Allison JP, Hwu P, Ajami NJ, Diab A, Wargo JA, Watowich SS. Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration. J Exp Med 220(2), 2023. e-Pub 2023. PMID: 36367776.
- Chrisikos TT, Zhou Y, Kahn LM, Patel B, Denne NL, Brooks A, Shen L, Wang J, Watowich SS. STAT3 Inhibits Autocrine IFN Signaling in Type I Conventional Dendritic Cells. J Immunol 209(7):1286-1299, 2022. e-Pub 2022. PMID: 36038291.
- Bhagat A, Shrestha P, Jeyabal P, Peng Z, Watowich SS, Kleinerman ES. Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase. Front Oncol 12:947604, 2022. e-Pub 2022. PMID: 36033503.
- Babcock RL, Zhou Y, Patel B, Chrisikos TT, Kahn LM, Dyevoich AM, Medik YB, Watowich SS. Regulation and function of Id2 in plasmacytoid dendritic cells. Mol Immunol 148:6-17, 2022. e-Pub 2022. PMID: 35640521.
- Zamler DB, Shingu T, Kahn LM, Huntoon K, Kassab C, Ott M, Tomczak K, Liu J, Li Y, Lai I, Zorilla-Veloz R, Yee C, Rai K, Kim BY, Watowich SS, Heimberger AB, Draetta GF, Hu J. Immune landscape of a genetically engineered murine model of glioma compared with human glioma. JCI Insight 7(12), 2022. e-Pub 2022. PMID: 35653194.
- Yuan B, Clowers MJ, Velasco WV, Peng S, Peng Q, Shi Y, Ramos-Castaneda M, Zarghooni M, Yang S, Babcock RL, Chang SH, Heymach JV, Zhang J, Ostrin EJ, Watowich SS, Kadara H, Moghaddam SJ. Targeting IL-1β as an immunopreventive and therapeutic modality for K-ras–mutant lung cancer. JCI Insight 7(11), 2022. e-Pub 2022. PMID: 35471938.
- Spencer CN, McQuade JL, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X, White MG, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, Andrews MC, Rodrigues RR, Morgun A, Kim YS, Roszik J, Hoffman KL, Zheng J, Zhou Y, Medik YB, Kahn LM, Johnson S, Hudgens CW, Wani K, Gaudreau PO, Harris AL, Jamal MA, Baruch EN, Perez-Guijarro E, Day CP, Merlino G, Pazdrak B, Lochmann BS, Szczepaniak-Sloane RA, Arora R, Anderson J, Zobniw CM, Posada E, Sirmans E, Simon J, Haydu LE, Burton EM, Wang L, Dang M, Clise-Dwyer K, Schneider S, Chapman T, Anang NAS, Duncan S, Toker J, Malke JC, Glitza IC, Amaria RN, Tawbi HA, Diab A, Wong MK, Patel SP, Woodman SE, Davies MA, Ross MI, Gershenwald JE, Lee JE, Hwu P, Jensen V, Samuels Y, Straussman R, Ajami NJ, Nelson KC, Nezi L, Petrosino JF, Futreal PA, Lazar AJ, Hu J, Jenq RR, Tetzlaff MT, Yan Y, Garrett WS, Huttenhower C, Sharma P, Watowich SS, Allison JP, Cohen L, Trinchieri G, Daniel CR, Wargo JA. Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response. Science 374(6575):1632-1640, 2021. e-Pub 2021. PMID: 34941392.
- Marié IJ, Brambilla L, Azzouz D, Chen Z, Baracho GV, Arnett A, Li HS, Liu W, Cimmino L, Chattopadhyay P, Silverman G, Watowich SS, Khor B, Levy DE. Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome. Elife 10, 2021. e-Pub 2021. PMID: 34378531.
- Andrews MC, Duong CPM, Gopalakrishnan V, Iebba V, Chen WS, Derosa L, Khan MAW, Cogdill AP, White MG, Wong MC, Ferrere G, Fluckiger A, Roberti MP, Opolon P, Alou MT, Yonekura S, Roh W, Spencer CN, Curbelo IF, Vence L, Reuben A, Johnson S, Arora R, Morad G, Lastrapes M, Baruch EN, Little L, Gumbs C, Cooper ZA, Prieto PA, Wani K, Lazar AJ, Tetzlaff MT, Hudgens CW, Callahan MK, Adamow M, Postow MA, Ariyan CE, Gaudreau PO, Nezi L, Raoult D, Mihalcioiu C, Elkrief A, Pezo RC, Haydu LE, Simon JM, Tawbi HA, McQuade J, Hwu P, Hwu WJ, Amaria RN, Burton EM, Woodman SE, Watowich S, Diab A, Patel SP, Glitza IC, Wong MK, Zhao L, Zhang J, Ajami NJ, Petrosino J, Jenq RR, Davies MA, Gershenwald JE, Futreal PA, Sharma P, Allison JP, Routy B, Zitvogel L, Wargo JA. Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade. Nat Med 27(8):1432-1441, 2021. e-Pub 2021. PMID: 34239137.
- Deng S, Ramos-Castaneda M, Velasco WV, Clowers MJ, Gutierrez BA, Noble O, Dong Y, Zarghooni M, Alvarado L, Caetano MS, Yang S, Ostrin EJ, Behrens C, Wistuba II, Stabile LP, Kadara H, Watowich SS, Moghaddam SJ. Interplay between estrogen and Stat3/NF-κB driven immunomodulation in lung cancer. Carcinogenesis 41(11):1529-1542, 2020. e-Pub 2020. PMID: 32603404.
- Wang J, Hasan F, Frey AC, Li HS, Park J, Pan K, Haymaker C, Bernatchez C, Lee DA, Watowich SS, Yee C. Histone deacetylase inhibitors and IL21 cooperate to reprogram human effector CD8+ T cells to memory T cells. Cancer Immunol Res 8(6):794-805, 2020. e-Pub 2020. PMID: 32213626.
- Zhou Y, Slone N, Chrisikos TT, Kyrysyuk O, Babcock RL, Medik YB, Li HS, Kleinerman ES, Watowich SS. Vaccine efficacy against primary and metastatic cancer with in vitro-generated CD103+ conventional dendritic cells. J Immunother Cancer 8(1), 2020. e-Pub 2020. PMID: 32273347.
- Chrisikos TT, Zhou Y, Li HS, Babcock RL, Wan X, Patel B, Newton K, Mancuso JJ, Watowich SS. STAT3 Inhibits CD103+ cDC1 Vaccine Efficacy in Murine Breast Cancer. Cancers (Basel) 12(1), 2020. e-Pub 2020. PMID: 31947933.
- Chu F, Li HS, Liu X, Cao J, Ma W, Ma Y, Weng J, Zhu Z, Cheng X, Wang Z, Liu J, Jiang ZY, Luong AU, Peng W, Wang J, Balakrishnan K, Yee C, Dong C, Davis RE, Watowich SS, Neelapu SS. CXCR5+CD8+ T cells are a distinct functional subset with an antitumor activity. Leukemia 33(11):2640-2653, 2019. e-Pub 2019. PMID: 31028278.
- Kettner NM, Vijayaraghavan S, Durak MG, Bui T, Kohansal M, Ha MJ, Liu B, Rao X, Wang J, Yi M, Carey JPW, Chen X, Eckols TK, Raghavendra AS, Ibrahim NK, Karuturi MS, Watowich SS, Sahin A, Tweardy DJ, Hunt KK, Tripathy D, Keyomarsi K. Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer. Clin Cancer Res 25(13):3996-4013, 2019. e-Pub 2019. PMID: 30867218.
- Zuo X, Deguchi Y, Xu W, Liu Y, Li HS, Wei D, Tian R, Chen W, Xu M, Yang Y, Gao S, Jaoude JC, Liu F, Chrieki SP, Moussalli MJ, Gagea M, Sebastian MM, Zheng X, Tan D, Broaddus R, Wang J, Ajami NJ, Swennes AG, Watowich SS, Shureiqi I. PPARD and interferon gamma promote transformation of gastric progenitor cells and tumorigenesis in mice. Gastroenterology 157(1):163-178, 2019. e-Pub 2019. PMID: 30885780.
- Li Y, Yang JY, Xie X, Jie Z, Zhang L, Shi J, Lin D, Gu M, Zhou X, Li HS, Watowich SS, Jain A, Yun Jung S, Qin J, Cheng X, Sun SC. Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization. Cell Res 29(6):474-485, 2019. e-Pub 2019. PMID: 31086255.
- Yan J, Zhao Q, Gabrusiewicz K, Kong LY, Xia X, Wang J, Ott M, Xu J, Davis RE, Huo L, Rao G, Sun SC, Watowich SS, Heimberger AB, Li S. FGL2 promotes tumor progression in the CNS by suppressing CD103(+) dendritic cell differentiation. Nat Commun 10(1):448, 2019. e-Pub 2019. PMID: 30683885.
- Caetano MS, Hassane M, Van HT, Bugarin E, Cumpian AM, McDowell CL, Cavazos CG, Zhang H, Deng S, Diao L, Wang J, Evans SE, Behrens C, Wistuba II, Fuqua SAW, Lin H, Stabile LP, Watowich SS, Kadara H, Moghaddam SJ. Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer. Nat Commun 9(1):4589, 2018. e-Pub 2018. PMID: 30389925.
- Zhang H, Li HS, Hillmer EJ, Zhao Y, Chrisikos TT, Hu H, Wu X, Thompson EJ, Clise-Dwyer K, Millerchip KA, Wei Y, Puebla-Osorio N, Kaushik S, Santos MA, Wang B, Garcia-Manero G, Wang J, Sun SC, Watowich SS. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis. Proc Natl Acad Sci U S A 115(10):E2311-E2319, 2018. e-Pub 2018. PMID: 29463696.
- Cardona SM, Kim SV, Church KA, Torres VO, Cleary IA, Mendiola AS, Saville SP, Watowich SS, Parker-Thornburg J, Soto-Ospina A, Araque P, Ransohoff RM, Cardona AE. Role of the fractalkine receptor in CNS autoimmune inflammation: new approach utilizing a mouse model expressing the human CX3CR1I249/M280 variant. Front Cell Neurosci 12:365, 2018. e-Pub 2018. PMID: 30386211.
- Fan F, Wang R, Boulbes DR, Zhang H, Watowich SS, Xia L, Ye X, Bhattacharya R, Ellis LM. Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway. PLoS One 13(1):e0190070, 2018. e-Pub 2018. PMID: 29293549.
- Kadmon CS, Landers CT, Li HS, Watowich SS, Rodriguez A, King KY. MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress in mice. Exp Hematol 56:7-15, 2017. e-Pub 2017. PMID: 28911907.
- Xiao Y, Zou Q, Xie X, Liu T, Li HS, Jie Z, Jin J, Hu H, Manyam G, Zhang L, Cheng X, Wang H, Marie I, Levy DE, Watowich SS, Sun SC. The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity. J Exp Med 214(5):1493-1507, 2017. e-Pub 2017. PMID: 28356390.
- Ni L, Wang L, Yao C, Ni Z, Liu F, Gong C, Zhu X, Yan X, Watowich SS, Lee DA, Zhu S. The histone deacetylase inhibitor valproic acid inhibits NKG2D expression in natural killer cells through suppression of STAT3 and HDAC3. Sci Rep 7:45266, 2017. e-Pub 2017. PMID: 28338101.
- Li HS, Liu C, Xiao Y, Chu F, Liang X, Peng W, Hu J, Neelapu SS, Sun SC, Hwu P, Watowich SS. Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells. Sci Signal 9(447):ra94, 2016. e-Pub 2016. PMID: 27678219.
- Li HS, Jin J, Liang X, Matatall KA, Ma Y, Zhang H, Ullrich SE, King KY, Sun SC, Watowich SS. Loss of c-Kit and bone marrow failure upon conditional removal of the GATA-2 C-terminal zinc finger domain in adult mice. Eur J Haematol 97(3):261-70, 2016. e-Pub 2016. PMID: 26660446.
- Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, Watowich SS, Moghaddam SJ. IL6 blockade reprograms the lung tumor microenvironment to limit the development and progression of K-ras-mutant lung cancer. Cancer Res 76(11):3189-99, 2016. e-Pub 2016. PMID: 27197187.
- Huang X, Li J, Dorta-Estremera S, Di Domizio J, Anthony SM, Watowich SS, Popkin D, Liu Z, Brohawn P, Yao Y, Schluns KS, Lanier LL, Cao W. Neutrophils regulate humoral autoimmunity by restricting interferon-γ production via the generation of reactive oxygen species. Cell Rep 12(7):1120-32, 2015. e-Pub 2015. PMID: 26257170.
- Mao F, Xu M, Zuo X, Yu J, Xu W, Moussalli MJ, Elias E, Li HS, Watowich SS, Shureiqi I. 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway. FASEB J 29(6):2359-70, 2015. e-Pub 2015. PMID: 25713055.
- Zhang H, Hu H, Greeley N, Jin J, Matthews AJ, Ohashi E, Caetano MS, Li HS, Wu X, Mandal PK, McMurray JS, Moghaddam SJ, Sun SC, Watowich SS. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nat Commun 5:5798, 2014. e-Pub 2014. PMID: 25503582.
- Zhu S, Phatarpekar PV, Denman CJ, Senyukov VV, Somanchi SS, Nguyen-Jackson HT, Mace EM, Freeman AF, Watowich SS, Orange JS, Holland SM, Lee DA. Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation. Blood 124(3):403-11, 2014. e-Pub 2014. PMID: 24891320.
- Zou Q, Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC. USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses. Nat Immunol 15(6):562-70, 2014. e-Pub 2014. PMID: 24777531.
- Jin J, Hu H, Li HS, Yu J, Xiao Y, Brittain GC, Zou Q, Cheng X, Mallette FA, Watowich SS, Sun SC. Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity. Immunity 40(3):342-54, 2014. e-Pub 2014. PMID: 24656046.
- Li HS, Watowich SS. Assessing the development of murine plasmacytoid dendritic cells in Peyer's patches using adoptive transfer of hematopoietic progenitors. J Vis Exp(85), 2014. e-Pub 2014. PMID: 24686788.
- Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C. The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nat Immunol 14(7):732-40, 2013. e-Pub 2013. PMID: 23727894.
- Liu C, Peng W, Xu C, Lou Y, Zhang M, Wargo JA, Chen JQ, Li HS, Watowich SS, Yang Y, Tompers Frederick D, Cooper ZA, Mbofung RM, Whittington M, Flaherty KT, Woodman SE, Davies MA, Radvanyi LG, Overwijk WW, Lizée G, Hwu P. BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clin Cancer Res 19(2):393-403, 2013. e-Pub 2013. PMID: 23204132.
- Nguyen-Jackson HT, Li HS, Zhang H, Ohashi E, Watowich SS. G-CSF-activated STAT3 enhances production of the chemokine MIP-2 in bone marrow neutrophils. J Leukoc Biol 92(6):1215-25, 2012. e-Pub 2012. PMID: 23024284.
- Li HS, Yang CY, Nallaparaju KC, Zhang H, Liu YJ, Goldrath AW, Watowich SS. The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development. Blood 120(22):4363-73, 2012. e-Pub 2012. PMID: 23033267.
- Nurieva RI, Podd A, Chen Y, Alekseev AM, Yu M, Qi X, Huang H, Wen R, Wang J, Li HS, Watowich SS, Qi H, Dong C, Wang D. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem 287(14):11234-9, 2012. e-Pub 2012. PMID: 22318729.
- Li HS, Greeley N, Sugimoto N, Liu YJ, Watowich SS. miR-22 controls Irf8 mRNA abundance and murine dendritic cell development. PLoS One 7(12):e52341, 2012. e-Pub 2012. PMID: 23251709.
- Yang CY, Best JA, Knell J, Yang E, Sheridan AD, Jesionek AK, Li HS, Rivera RR, Lind KC, D'Cruz LM, Watowich SS, Murre C, Goldrath AW. The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nat Immunol 12(12):1221-9, 2011. e-Pub 2011. PMID: 22057289.
- Li HS, Gelbard A, Martinez GJ, Esashi E, Zhang H, Nguyen-Jackson H, Liu YJ, Overwijk WW, Watowich SS. Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response. Blood 118(14):3879-89, 2011. e-Pub 2011. PMID: 21828128.
- Zhang H, Nguyen-Jackson H, Panopoulos AD, Li HS, Murray PJ, Watowich SS. STAT3 controls myeloid progenitor growth during emergency granulopoiesis. Blood 116(14):2462-71, 2010. e-Pub 2010. PMID: 20581311.
- Qualls JE, Neale G, Smith AM, Koo MS, DeFreitas AA, Zhang H, Kaplan G, Watowich SS, Murray PJ. Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling. Sci Signal 3(135):ra62, 2010. e-Pub 2010. PMID: 20716764.
- Nguyen-Jackson H, Panopoulos AD, Zhang H, Li HS, Watowich SS. STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction. Blood 115(16):3354-63, 2010. e-Pub 2010. PMID: 20185584.
- Hegde S, Ni S, He S, Yoon D, Feng GS, Watowich SS, Paulson RF, Hankey PA. Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiation. Oncogene 28(38):3349-59, 2009. e-Pub 2009. PMID: 19581930.
- Speiran K, Bailey DP, Fernando J, Macey M, Barnstein B, Kolawole M, Curley D, Watowich SS, Murray PJ, Oskeritzian C, Ryan JJ. Endogenous suppression of mast cell development and survival by IL-4 and IL-10. J Leukoc Biol 85(5):826-36, 2009. e-Pub 2009. PMID: 19228815.
- Chung Y, Chang SH, Martinez GJ, Yang XO, Nurieva R, Kang HS, Ma L, Watowich SS, Jetten AM, Tian Q, Dong C. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30(4):576-87, 2009. e-Pub 2009. PMID: 19362022.
- Yamazaki T, Yang XO, Chung Y, Fukunaga A, Nurieva R, Pappu B, Martin-Orozco N, Kang HS, Ma L, Panopoulos AD, Craig S, Watowich SS, Jetten AM, Tian Q, Dong C. CCR6 regulates the migration of inflammatory and regulatory T cells. J Immunol 181(12):8391-401, 2008. e-Pub 2008. PMID: 19050256.
- Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, Shah B, Chang SH, Schluns KS, Watowich SS, Feng XH, Jetten AM, Dong C. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 29(1):44-56, 2008. e-Pub 2008. PMID: 18585065.
- Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, Ma L, Wang YH, Watowich SS, Jetten AM, Tian Q, Dong C. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 29(1):138-49, 2008. e-Pub 2008. PMID: 18599325.
- Esashi E, Wang YH, Perng O, Qin XF, Liu YJ, Watowich SS. The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8. Immunity 28(4):509-20, 2008. e-Pub 2008. PMID: 18342552.
- Kennedy Norton S, Barnstein B, Brenzovich J, Bailey DP, Kashyap M, Speiran K, Ford J, Conrad D, Watowich S, Moralle MR, Kepley CL, Murray PJ, Ryan JJ. IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo. J Immunol 180(5):2848-54, 2008. e-Pub 2008. PMID: 18292506.
- Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 28(1):29-39, 2008. e-Pub 2008. PMID: 18164222.
- El Kasmi KC, Smith AM, Williams L, Neale G, Panopoulos AD, Panopolous A, Watowich SS, Häcker H, Foxwell BM, Murray PJ. Cutting edge: A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway. J Immunol 179(11):7215-9, 2007. e-Pub 2007. PMID: 18025162.
- Kile BT, Panopoulos AD, Stirzaker RA, Hacking DF, Tahtamouni LH, Willson TA, Mielke LA, Henley KJ, Zhang JG, Wicks IP, Stevenson WS, Nurden P, Watowich SS, Justice MJ. Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia. Blood 110(7):2371-80, 2007. e-Pub 2007. PMID: 17515402.
- Nurieva R, Yang XO, Martinez G, Zhang Y, Panopoulos AD, Ma L, Schluns K, Tian Q, Watowich SS, Jetten AM, Dong C. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 448(7152):480-3, 2007. e-Pub 2007. PMID: 17581589.
- Yang XO, Panopoulos AD, Nurieva R, Chang SH, Wang D, Watowich SS, Dong C. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem 282(13):9358-63, 2007. e-Pub 2007. PMID: 17277312.
- Panopoulos AD, Zhang L, Snow JW, Jones DM, Smith AM, El Kasmi KC, Liu F, Goldsmith MA, Link DC, Murray PJ, Watowich SS. STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils. Blood 108(12):3682-90, 2006. e-Pub 2006. PMID: 16888100.
- El Kasmi KC, Holst J, Coffre M, Mielke L, de Pauw A, Lhocine N, Smith AM, Rutschman R, Kaushal D, Shen Y, Suda T, Donnelly RP, Myers MG, Alexander W, Vignali DA, Watowich SS, Ernst M, Hilton DJ, Murray PJ. General nature of the STAT3-activated anti-inflammatory response. J Immunol 177(11):7880-8, 2006. e-Pub 2006. PMID: 17114459.
- Zhang L, Badgwell DB, Bevers JJ, Schlessinger K, Murray PJ, Levy DE, Watowich SS. IL-6 signaling via the STAT3/SOCS3 pathway: functional analysis of the conserved STAT3 N-domain. Mol Cell Biochem 288(1-2):179-89, 2006. e-Pub 2006. PMID: 16718380.
- Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE. Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. Angiogenesis 9(2):101-10, 2006. e-Pub 2006. PMID: 16871430.
- Nishimoto A, Yu Y, Lu Z, Mao X, Ren Z, Watowich SS, Mills GB, Liao WS, Chen X, Bast RC, Luo RZ. A ras homologue member I directly inhibits signal transducers and activators of transcription 3 translocation and activity in human breast and ovarian cancer cells. Cancer Res 65(15):6701-10, 2005. e-Pub 2005. PMID: 16061651.
- Gray MJ, Zhang J, Ellis LM, Semenza GL, Evans DB, Watowich SS, Gallick GE. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene 24(19):3110-20, 2005. e-Pub 2005. PMID: 15735682.
- Butcher BA, Kim L, Panopoulos AD, Watowich SS, Murray PJ, Denkers EY. IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages. J Immunol 174(6):3148-52, 2005. e-Pub 2005. PMID: 15749841.
- Wang L, Arcasoy MO, Watowich SS, Forget BG. Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells. Exp Hematol 33(3):308-17, 2005. e-Pub 2005. PMID: 15730854.
- Pauleau AL, Rutschman R, Lang R, Pernis A, Watowich SS, Murray PJ. Enhancer-mediated control of macrophage-specific arginase I expression. J Immunol 172(12):7565-73, 2004. e-Pub 2004. PMID: 15187136.
- Yoon D, Watowich SS. Hematopoietic cell survival signals are elicited through non-tyrosine-containing sequences in the membrane-proximal region of the erythropoietin receptor (EPOR) by a Stat5-dependent pathway. Exp Hematol 31(12):1310-6, 2003. e-Pub 2003. PMID: 14662339.
- Sarna MK, Ingley E, Busfield SJ, Cull VS, Lepere W, McCarthy DJ, Wright MJ, Palmer GA, Chappell D, Sayer MS, Alexander WS, Hilton DJ, Starr R, Watowich SS, Bittorf T, Klinken SP, Tilbrook PA. Differential regulation of SOCS genes in normal and transformed erythroid cells. Oncogene 22(21):3221-30, 2003. e-Pub 2003. PMID: 12761492.
- Panopoulos AD, Bartos D, Zhang L, Watowich SS. Control of myeloid-specific integrin alpha Mbeta 2 (CD11b/CD18) expression by cytokines is regulated by Stat3-dependent activation of PU.1. J Biol Chem 277(21):19001-7, 2002. e-Pub 2002. PMID: 11889125.
- Afrikanova I, Yeh E, Bartos D, Watowich SS, Longmore GD. Oncogene cooperativity in Friend erythroleukemia: erythropoietin receptor activation by the env gene of SFFV leads to transcriptional upregulation of PU.1, independent of SFFV proviral insertion. Oncogene 21(8):1272-84, 2002. e-Pub 2002. PMID: 11850847.
- Kubatzky KF, Ruan W, Gurezka R, Cohen J, Ketteler R, Watowich SS, Neumann D, Langosch D, Klingmüller U. Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor. Curr Biol 11(2):110-5, 2001. e-Pub 2001. PMID: 11231127.
- Watowich SS, Mikami A, Busche RA, Xie X, Pharr PN, Longmore GD. Erythropoietin receptors that signal through Stat5 or Stat3 support fetal liver and adult erythropoiesis: lack of specificity of stat signals during red blood cell development. J Interferon Cytokine Res 20(12):1065-70, 2000. e-Pub 2000. PMID: 11152572.
- Wooten DK, Xie X, Bartos D, Busche RA, Longmore GD, Watowich SS. Cytokine signaling through Stat3 activates integrins, promotes adhesion, and induces growth arrest in the myeloid cell line 32D. J Biol Chem 275(34):26566-75, 2000. e-Pub 2000. PMID: 10858439.
- Cull V, Tilbrook PA, Adenan AS, Chappell D, Ingley E, Sarna MK, Palmer TN, Watowich SS, Klinken SP. Dominant action of mutated erythropoietin receptors on differentiation in vitro and erythroleukemia development in vivo. Oncogene 19(7):953-60, 2000. e-Pub 2000. PMID: 10702804.
- Watowich SS, Xie X, Klingmuller U, Kere J, Lindlof M, Berglund S, de la Chapelle A. Erythropoietin receptor mutations associated with familial erythrocytosis cause hypersensitivity to erythropoietin in the heterozygous state. Blood 94(7):2530-2, 1999. e-Pub 1999. PMID: 10498627.
- Watowich SS, Liu KD, Xie X, Lai SY, Mikami A, Longmore GD, Goldsmith MA. Oligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail. J Biol Chem 274(9):5415-21, 1999. e-Pub 1999. PMID: 10026152.
- Levin I, Cohen J, Supino-Rosin L, Yoshimura A, Watowich SS, Neumann D. Identification of a cytoplasmic motif in the erythropoietin receptor required for receptor internalization. FEBS Lett 427(2):164-70, 1998. e-Pub 1998. PMID: 9607304.
- Tarr K, Watowich SS, Longmore GD. Cell surface organization of the erythropoietin receptor complex differs depending on its mode of activation. J Biol Chem 272(14):9099-107, 1997. e-Pub 1997. PMID: 9083037.
- Hilton DJ, Watowich SS, Katz L, Lodish HF. Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor. J Biol Chem 271(9):4699-708, 1996. e-Pub 1996. PMID: 8617735.
- Murray PJ, Watowich SS, Lodish HF, Young RA, Hilton DJ. Epitope tagging of the human endoplasmic reticulum HSP70 protein, BiP, to facilitate analysis of BiP--substrate interactions. Anal Biochem 229(2):170-9, 1995. e-Pub 1995. PMID: 7485969.
- Hilton DJ, Watowich SS, Murray PJ, Lodish HF. Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor. Proc Natl Acad Sci U S A 92(1):190-4, 1995. e-Pub 1995. PMID: 7816815.
- Watowich SS, Hilton DJ, Lodish HF. Activation and inhibition of erythropoietin receptor function: role of receptor dimerization. Mol Cell Biol 14(6):3535-49, 1994. e-Pub 1994. PMID: 8196600.
- Longmore G, Watowich S, Pharr P, Neumann D, Lodish H. Activation of the erythropoietin receptor and leukemia induction in mice. Leukemia 7 Suppl 2:S113-6, 1993. e-Pub 1993. PMID: 8361212.
- Neumann D, Wikström L, Watowich SS, Lodish HF. Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes. J Biol Chem 268(18):13639-49, 1993. e-Pub 1993. PMID: 8514796.
- Watowich SS, Yoshimura A, Longmore GD, Hilton DJ, Yoshimura Y, Lodish HF. Homodimerization and constitutive activation of the erythropoietin receptor. Proc Natl Acad Sci U S A 89(6):2140-4, 1992. e-Pub 1992. PMID: 1312714.
- Ng DT, Watowich SS, Lamb RA. Analysis in vivo of GRP78-BiP/substrate interactions and their role in induction of the GRP78-BiP gene. Mol Biol Cell 3(2):143-55, 1992. e-Pub 1992. PMID: 1550958.
- Lodish HF, Hilton D, Longmore G, Watowich SS, Yoshimura A. The erythropoietin receptor: dimerization, activation, and tumorigenesis. Cold Spring Harb Symp Quant Biol 57:95-106, 1992. e-Pub 1992. PMID: 1339709.
- Watowich SS, Morimoto RI, Lamb RA. Flux of the paramyxovirus hemagglutinin-neuraminidase glycoprotein through the endoplasmic reticulum activates transcription of the GRP78-BiP gene. J Virol 65(7):3590-7, 1991. e-Pub 1991. PMID: 2041085.
- Watowich SS, Morimoto RI. Complex regulation of heat shock- and glucose-responsive genes in human cells. Mol Cell Biol 8(1):393-405, 1988. e-Pub 1988. PMID: 3275876.
- Minowa T, Keshari S, He S, Saha A, Shavkunov AS, Pineda JE, Yeo YY, Zhu B, Mohanty B, Jindal S, Chen K, Hu KH, Wang L, Nolan GP, Watowich SS, Gubin MM. Spatial immune hubs defined by conserved activated dendritic cells are remodeled by immunotherapy. bioRxiv. PMID: 41726948.
- Chaib M, Aminu M, Herbrich S, Arabi M, Xuan Y, Basi A, Casasent A, Macaluso MD, Hu KH, Gubin M, Chen X, Mancuso JJ, Basu S, Jindal S, Burks J, Watowich SS, Wu J, Allison JP, Sharma P. Macrophage-Dendritic Cell-T-Cell Tetrads Orchestrate Antitumor Immunity and Response to Checkpoint Blockade. bioRxiv. PMID: 41509466.
- Pineda JE, Minowa T, Shen L, Zhou Y, Dyevoich AM, Patel B, Schneider SM, Keshari S, Saha A, Riba MN, Wang J, Watowich SS, Gubin MM. Antigen presentation requirements for effective cDC1-based cancer immunotherapy. bioRxiv. PMID: 41659662.
Review Articles
- Wang Y, Jenq RR, Wargo JA, Watowich SS. Microbiome influencers of checkpoint blockade–associated toxicity. J Exp Med 220(3), 2023. e-Pub 2023. PMID: 36622383.
- Wurster S, Watowich SS, Kontoyiannis DP. Checkpoint inhibitors as immunotherapy for fungal infections. Front Immunol 13:1018202, 2022. e-Pub 2022. PMID: 36389687.
- Chrisikos TT, Zhou Y, Slone N, Babcock R, Watowich SS, Li HS. Molecular regulation of dendritic cell development and function in homeostasis, inflammation, and cancer. Mol Immunol 110:24-39, 2019. e-Pub 2019. PMID: 29549977.
- Hillmer EJ, Zhang H, Li HS, Watowich SS. STAT3 signaling in immunity. Cytokine Growth Factor Rev 31:1-15, 2016. e-Pub 2016. PMID: 27185365.
- Li HS, Watowich SS. Innate immune regulation by STAT-mediated transcriptional mechanisms. Immunol Rev 261(1):84-101, 2014. e-Pub 2014. PMID: 25123278.
- Munoz J, Dhillon N, Janku F, Watowich SS, Hong DS. STAT3 inhibitors: finding a home in lymphoma and leukemia. Oncologist 19(5):536-44, 2014. e-Pub 2014. PMID: 24705981.
- Li HS, Watowich SS. Diversification of dendritic cell subsets: Emerging roles for STAT proteins. JAKSTAT 2(4):e25112, 2013. e-Pub 2013. PMID: 24416644.
- Li HS, Watowich SS. A STATus report on DC development. J Leukoc Biol 92(3):445-59, 2012. e-Pub 2012. PMID: 22550127.
- Watowich SS. The erythropoietin receptor: molecular structure and hematopoietic signaling pathways. J Investig Med 59(7):1067-72, 2011. e-Pub 2011. PMID: 21307776.
- Watowich SS, Liu YJ. Mechanisms regulating dendritic cell specification and development. Immunol Rev 238(1):76-92, 2010. e-Pub 2010. PMID: 20969586.
- Panopoulos AD, Watowich SS. Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis. Cytokine 42(3):277-288, 2008. e-Pub 2008. PMID: 18400509.
- Watowich SS. Activation of erythropoietin signaling by receptor dimerization. Int J Biochem Cell Biol 31(10):1075-88, 1999. e-Pub 1999. PMID: 10582340.
- Watowich SS, Wu H, Socolovsky M, Klingmuller U, Constantinescu SN, Lodish HF. Cytokine receptor signal transduction and the control of hematopoietic cell development. Annu Rev Cell Dev Biol 12:91-128, 1996. e-Pub 1996. PMID: 8970723.
- Lodish HF, Hilton DJ, Klingmüller U, Watowich SS, Wu H. The erythropoietin receptor: biogenesis, dimerization, and intracellular signal transduction. Cold Spring Harb Symp Quant Biol 60:93-104, 1995. e-Pub 1995. PMID: 8824381.
- Longmore GD, Watowich SS, Hilton DJ, Lodish HF. The erythropoietin receptor: its role in hematopoiesis and myeloproliferative diseases. J Cell Biol 123(6 Pt 1):1305-8, 1993. e-Pub 1993. PMID: 8253831.
- Schneider SM, Fan C, Wang Y, Jenq RR, Watowich SS. Microbiota and immune-related adverse events in cancer immunotherapy. Nat Rev Cancer.
Professional Educational Materials
- . Molecular Signaling Google Groups Website, 2011.
- . Cytokines and immune response google groups website, 2008.
Other Articles
- Watowich SS Microbial messaging to the marrow. Blood 124(9):1379-80, 2014. PMID: 25170108.
- Esashi E, Watowich SS Dendritic cells: transcriptional control of plasmacytoid dendritic cell development by E2-2. Immunol Cell Biol 87(1):1-2, 2009. PMID: 19048021.
Editorials
- Nicholson SE, Watowich SS. Introduction to the special issue: the tumor microenvironment and molecular regulation of innate immune cells. Mol Immunol 110:1-2, 2019. PMID: 30318379.
Book Chapters
- Zhang, H, Li, H, Watowich, SS. Jak-STAT Signaling Pathways, V3:699-V3:711, 2025.
- Zhang H, Li HS, Watowich SS. Jak-STAT signaling pathways. In: Encyclopedia of Immunobiology. Oxford: Academic Press, 134–145, 2016.
- Nguyen-Jackson H, Zhang H, Watowich SS. G-CSF receptor structure, function and intracellular signal transduction. In: 20 Years of G-CSF: Clinical and Nonclinical Discoveries. Birkhäuser Verlag AG, 2012.
- Li HS, Watowich SS. Regulation of dendritic cell development by STATs. In: Jak-Stat Signaling: From Basics to Disease. Springer Verlag, 169-186, 2012.
- Watowich SS. Erythropoietin. In: Colony Stimulating Factors Molecular and Cellular Biology. 2. M Dekker, 291-313, 1996.
- Hilton DJ, Watowich SS. The erythropoietin receptor. In: Guidebook to Cytokines and their Receptors. Oxford University Press, 155-157, 1994.
Patient Reviews
CV information above last modified July 22, 2026