Thomas H. Beckham, M.D., Ph.D.
Department of CNS - Rad Onc Clinical, Division of Radiation Oncology
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of CNS - Rad Onc Clinical, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2015 | Medical University of South Carolina, Charleston, South Carolina, US, Medicine, MD |
| 2015 | Medical University of South Carolina, Charleston, South Carolina, US, Molecular Biology, Ph.D |
| 2007 | Clemson University, Clemson, South Carolina, US, Genetics, BS |
Postgraduate Training
| 2019-2020 | Chief Resident, Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York |
| 2016-2020 | Residency, Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York |
| null-2016 | Internship, Memorial Sloan Kettering Cancer Center, New York, NY |
Licenses & Certifications
| 2023 | Mississippi State Board of Medical Licensure |
| 2023 | Arizona Board of Medical Examiners |
| 2023 | Washington State Department of Health |
| 2023 | Tennessee Board of Medical Examiners |
| 2023 | Louisiana State Board of Medical Examiners |
| 2023 | Georgia Composite Medical Board |
| 2023 | Oklahoma State Board of Medical Licensure |
| 2023 | Alabama Board of Medical Examiners |
| 2021 | Florida Board of Medicine |
| 2020 | DEA |
| 2020 | American Board of Radiology: Diplomate of Radiation Oncology |
| 2020 | Texas State Medical License |
| 2019 | American Board of Radiology: Initial Cert. Physics and Radiation Biology |
| 2015 | New York State Medical Permit |
| 2008 | NBME Step I, Step II CS and CK, and Step III |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - 2026
Administrative Appointments/Responsibilities
Cancer Neurosciences Program Neural Neoplasm Director, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
CNS Residency Education Director, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2023 - Present
Associate Director of Gamma Knife Program, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2023 - Present
Associate Medical Director, Brain and Spine Center, The University of Texas MD Anderson Cancer Center, Houston, TX, 2023 - Present
Other Professional Positions
Clinical Clerkship Teaching Professor, University of Houston College of Medicine, Houston, TX, 2021
Resident Education Committee, Memorial Sloan Kettering Cancer Center, New York, NY, 2019 - 2020
Chief Resident, Memorial Sloan Kettering Cancer Center, New York, NY, 2019 - 2020
Memorial Sloan Kettering Cancer Center Ethics Committee, Memorial Sloan Kettering Cancer Center, New York, NY, 2015 - 2016
Transitional Year Intern, Memorial Sloan Kettering Cancer Center, New York, NY, 2015 - 2016
Intramural Institutional Committee Activities
Member, Physicians Referal Service (PRS) Executive Council, The University of Texas MD Anderson Cancer Center, 2025 - Present
Extramural Institutional Committee Activities
Member, Ride Out Team, The University of Texas MD Anderson Cancer Center, 2024 - Present
Member, Scientific Review Committee, The University of Texas MD Anderson Cancer Center, 2022 - Present
Member, Data Biospecimine Access Committee, The University of Texas MD Anderson Cancer Center, 2022 - 2024
Chair, Department of Radiation Oncology CNS/Pediatrics Social Chair, The University of Texas MD Anderson Cancer Center, 2022 - Present
Member, Department of Radiation Oncology Faculty Search Committee, The University of Texas MD Anderson Cancer Center, 2021 - Present
Honors & Awards
| 2025 - Present | Best Young Investigator Award for the Americas, Leksell Gamma Knife Society |
| 2014 | Alpha Omega Alpha, Medical University of South Carolina |
| 2013 | MUSC Student Leadership Society, Medical University of South Carolina |
| 2012 | College of Medicine Most Outstanding Student Volunteer, Medical University of South Carolina |
| 2011 - 2013 | Department of Defense Prostate Cancer Training Award, Medical University of South Carolina |
| 2009 - 2010 | Hollings Cancer Center Wachovia Scholarship, Medical University of South Carolina |
| 2009 | GAANN Fellowship, Medical University of South Carolina |
| 2008 | Infection and Immunity: Excellence in Writing Award, Medical University of South Carolina |
| 2007 - 2008 | Lane Family Scholarship, Medical University of South Carolina |
| 2007 - 2008 | Suzann Pershing Scholarship, Medical University of South Carolina |
| 2007 - 2008 | University Medical Associates MSTP Scholarship, Medical University of South Carolina |
| 2007 | Clemson University College of Agriculture, Forestry and Life Sciences Outstanding Student, Clemson University |
| 2007 | Clemson University Genetics Program Outstanding Student Award, Clemson University |
| 2007 | Phi Beta Kappa Society Member, Clemson University |
| 2007 | Sigma Xi Honorary Member, Clemson University |
| 2004 - 2007 | Abney Foundation Scholar, Clemson University |
| 2004 - 2007 | Clemson University Coca-Cola Scholar, Clemson University |
| 2004 - 2007 | Clemson University President’s List, Clemson University |
| 2004 - 2007 | South Carolina Palmetto Fellow, Clemson University |
| 2004 - 2007 | Summa Cum Laude, Clemson University |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2025. GBM in elderly patients. Invited. Neuro-Oncology Journal Club. Houston, Texas, US.
- 2025. EXCLAIM: EXploring Combined Local and systemic Approaches In brain Metastasis. Invited. Brain Mets Retreat. Houston, Texas, US.
- 2025. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2025. EXCLAIM: EXploring Combined Local and systemic Approaches In brain Metastasis. Invited. Rad Onc Research Retreat. Houston, Texas, US.
- 2025. Practical Radiosurgery. Invited. Houston, Texas, US.
- 2025. Evolution of Management of Brain Metastases. Invited. Clinical Neurosciences Seminar. Houston, Texas, US.
- 2025. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2025. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2024. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2024. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2024. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2024. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2024. Evolution of Local and Systemic Therapies for Optimal Management of Brain Metastases. Invited. CCSG Retreat. Houston, Texas, US.
- 2024. CNS Oral Boards Prep Lecture. Invited. Houston, Texas, US.
- 2024. Practical Radiosurgery. Invited. Houston, Texas, US.
- 2024. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2024. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2023. Best of ASTRO CNS Review. Invited. Houston, Texas, US.
- 2023. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2023. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2023. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2023. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2023. Evolution of Management of Brain Metastases. Invited. Clinical Neurosciences Seminar. Houston, Texas, US.
- 2023. Practical Radiosurgery. Invited. Houston, Texas, US.
- 2023. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2023. CNS Oral Boards Prep Lecture. Invited. Houston, Texas, US.
- 2023. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2022. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2022. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2022. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2022. Anaplastic Gliomas. Invited. Clinical Neurosciences Seminar. Houston, Texas, US.
- 2022. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2022. Brain Metastasis Management. Invited. Houston, Texas, US.
- 2022. Multi-D Management of Spine Metastases. Invited. Clinical Neurosciences Seminar. Houston, Texas, US.
- 2022. Brain Metastasis Management. Invited. Houston, Texas, US.
Regional Presentations
- 2022. Grand Round-up. Panelist, TX, US.
National Presentations
- 2026. Brain Metastases in Melanoma. Invited. AIM at Melanoma Symposium on Brain Metastases in Melanoma. Plano, Texas, US.
- 2026. GammaTile brachytherapy for CNS cancers. Invited. Radiation Oncology Virtual Education Rotation (ROVER), US.
- 2025. An overview of how modern brachytherapy delivers highly targeted radiation to achieve excellent local control while minimizing toxicity. Invited, US.
- 2025. Gamma tile brain met trial. Invited. NIH/NCI Brain Metastases Interest Group Meeting. Houston, Texas, US.
- 2025. Brachytherapy for high grade gliomas. Invited. Los Angeles, CA, US.
- 2025. Radiation One And Done Study (ROADS): A phase III RCT of post-op SRS versus STaRT with GammaTile for newly diagnosed brain metastases. Invited. Scottsdale, AZ, US.
- 2024. CNS BRACHYTHERAPY: MANAGEMENT OF PRIMARY AND METASTATIC BRAIN LESIONS. Invited. Maryland, US.
- 2024. A phase 3 randomized controlled trial of post-surgical stereotactic radiotherapy versus surgically targeted radiation therapy with Cs-131 collagen tile brachytherapy for treatment of newly diagnosed metastatic brain tumors. Invited. Chicago, US.
- 2024. WHEN SRS FAILS: MANAGEMENT OF RECURRENCE AFTER CRANIAL SRS. Invited. New York, US.
- 2024. Radiosurgery for 5 or more brain metastases in the systemic therapy era. Poster. Chicago, US.
- 2023. Spine stereotactic radiosurgery in the management of metastatic pheochromocytoma. Invited. ESTRO, US.
- 2023. Update on ROADS Trial Cs-131 Brachytherapy versus post op SRS for surgical brain mets. Invited. Scottsdale, AZ, US.
- 2023. CNS Brachytherapy. Invited, US.
- 2022. MD Anderson Cancer Center GammaTile Experience and Update on ROADS Trial. Invited, US.
- 2019. Early urinary toxicity outcomes with low dose rate versus high dose rate brachytherapy boost combined with ultrahypofractionated external beam radiotherapy for high- and intermediate-risk prostate cancer. Invited. 2019 American Brachytherapy Society Annual Meeting. Miami, FL, US.
- 2018. A Multi-Institutional Comparison of Carboplatin-Based Regimens Versus Cetuximab in Chemoradiation for p16(-) Head and Neck Cancer. Conference. 2018 ASTRO Annual Meeting. San Antonio, TX, US.
- 2018. Local Therapy in the Definitive Management of Castleman Disease. Invited. 2018 ASTRO Annual Meeting. San Antonio, TX, US.
- 2018. Impact of Surgery and External Beam Radiotherapy on Local Control in the Treatment of Medullary Thyroid Carcinoma. Invited. 2018 ASTRO Annual Meeting. San Antonio, TX, US.
- 2017. Intensity Modulated Radiation Therapy with or without Concurrent Chemotherapy in Non- Anaplastic Thyroid Cancer with Unresectable or Gross Residual Disease. Invited. 2017 ASTRO Annual Meeting. San Diego, CA, US.
- 2012. Sphingosine 1-phosphate and acid ceramidase modulate the subcellular localization of the PTEN tumor suppressor. Invited. 2012 Medical University of South Carolina Medical Scientist Training Program Research Day. Charleston, SC, US.
- 2012. Sphingosine 1-phosphate and acid ceramidase modulate the subcellular localization of the PTEN tumor suppressor. Conference. 2012 MUSC Lipid Signaling In Cancer Program Retreat. Charleston, SC, US.
- 2012. 2012 Medical University of South Carolina Medical Scientist Training Program Research Day. Invited. 2012 Medical University of South Carolina Medical Scientist Training Program Research Day. Charleston, SC, US.
- 2012. Small Molecule Platform for Improving Radiation Therapy of Prostate Cancer. Invited. 2012 University of California San Diego Rady School of Management Student Venture Open Competition. San Diego, CA, US.
- 2012. Sphingolipid-mediated regulation of nuclear PTEN. Invited. 2012 Hollings Cancer Center Research Retreat. Charleston, SC, US.
- 2011. Sphingosine 1-phosphate and acid ceramidase modulate the subcellular localization of the PTEN tumor suppressor. Invited. 2011 Medical University of South Carolina Student Research Day. Charleston, SC, US.
- 2010. Evaluating the Impact of Acid Ceramidase Overexpression on Activation of and Addiction to the PKB/Akt Pathway. Conference. 2010 Medical University of South Carolina Student Research Day. Charleston, SC, US.
- 2010. Acid Ceramidase-Mediated Regulation of the Akt/PTEN Pathway in Prostate Cancer. Invited. 2010 Hollings Cancer Center Genitourinary Cancer Symposium. Charleston, SC, US.
- 2009. Acid Ceramidase Upregulation Following Radiation Therapy Desensitizes Cancer Cells to Taxol. Invited. 2009 MD/PhD National Student Conference. Keystone, CO, US.
- 2008. Acid Ceramidase Upregulation Following Radiation Therapy Desensitizes Cancer Cells to Taxol. Conference. 2008 Medical University of South Carolina Student Research Day. Charleston, SC, US.
- 2007. Evaluation of Combinatorial FasL and Radiation Therapies in Prostate Cancer. Conference. 2007 Medical University of South Carolina Student Research Day. Charleston, SC, US.
International Presentations
- 2026. Oral Presentation – Intracranial Brain Metastases. Invited. ISRS. Sydney, AU.
- 2025. Insurance approval process for proton craniospinal irradiation for patients with leptomeningeal disease in a large cancer center in the United States. Poster. PTCOG. Buenos Aires, AR.
- 2024. Management of brain metastases in the era of immunotherapy. Invited. Istanbul, TR.
- 2023. Reirradiation approaches of malignant glioma. Invited. Santiago, CL.
- 2023. Hot Topics in CNS Radiation Oncology. Invited. Santiago, CL.
- 2012. Sphingosine 1-phosphate and acid ceramidase modulate the subcellular localization of the PTEN tumor suppressor. Invited. 2012 Gordon Research Conference on Glycolipid and Sphingolipid Biology. Lucca, IT.
- 2011. Acid Ceramidase-Mediated Regulation of the Akt/PTEN Pathway. Invited. 2011 Charleston Ceramide Conference. Villars sur Ollon, CH.
Formal Peers
- 2025. Nursing education for CNS tumors, US.
- 2023. CNS Brachytherapy. Invited, US.
Grant & Contract Support
| Date: | 2026 - 2027 |
| Title: | Brain Metastasis Clinic Pilot Award - FLASH Radiotherapy for CNS Metastases |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | PI |
| Date: | 2026 - 2030 |
| Title: | CPRIT Individual Investigator Research Awards for Clinical Trials |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | PI |
| Date: | 2026 - 2031 |
| Title: | Clinical Decision Support Tool for Guiding Local Therapy in Melanoma Brain Metastases through Lesion-level Modeling of Immunotherapy Response |
| Funding Source: | NIH |
| Role: | Co-I |
| Date: | 2026 - 2031 |
| Title: | Clinical Decision Support Tool for Guiding Local Therapy in Melanoma Brain Metastases through Lesion-level Modeling of Immunotherapy Response |
| Funding Source: | NIH |
| Role: | Co-I |
| Title: | Radiation Oncology Strategic Initiatives (ROSI)- Quality and Safety-“Integration of Multidisciplinary Volume Review to Improve Safety, Quality and Efficiency of Spine Radiosurgery” |
| Funding Source: | ROSI |
| Role: | PI |
| Title: | Evaluation of radiomic features in the prediction of the outcome of oligometastatic head and neck cancer |
| Funding Source: | American College of Radiation Oncology Seed Grant |
| Role: | Investigator |
| Title: | Gilbert Fletcher Rising Star Award- “Development of [18F] DASA-PET at MDACC for Metabolic Imaging in Glioblastoma” |
| Funding Source: | ROSI |
| Role: | PI |
Selected Publications
Peer-Reviewed Articles
- Carriere, P, Haisraely, O, Aaroe, AE, Ahmed, K, Lewis, R, Colson-Fearon, D, Bolden, M, Swanson, T, Beckham, TH, Wang, C, De, BS, Perni, S, Tom, MC, Li, J, McGovern, SL, McAleer, MF, Ghia, AJ, Jiang, W, Chung, C, Grosshans, DR, Ballester, L, Esquenazi, Y, Kamiya Matsuoka, C, Yeboa, DN. Long-term outcomes in IDH-wildtype (IDH-wt) gliomas with historical WHO grade 2 and 3 histology. Journal of neuro-oncology 179(1), 2026. e-Pub 2026. PMID: 42489814.
- Call-Orellana, F, Zuluaga-Garcia, JP, de Almeida, R, Beck, A, Beckham, TH, Ghia, AJ, Li, J, Tom, MC, McAleer, MF, Perni, S, Wang, C, Yeboa, DN, Cross, KA, Alvarez-Breckenridge, C, Kimchi, G, Rhines, LD, Tatsui, CE, North, RY. Applicability of RECIST1.1, MDACC and SPINO Tumor Response Criteria After Adjuvant Stereotactic Spinal Radiosurgery in Surgically Treated Spinal Metastases. Medicina (Lithuania) 62(7), 2026. e-Pub 2026. PMID: 42512796.
- Khalaf, A, Naya, L, Flynt, L, Surasi, DS, Lu, Y, Nagpal, S, Thomas, R, Recht, L, Beckham, TH, Liu, HL, Davidzon, G, Beinat, C, Patel, C. [18F]DASA-23 PET/MRI evaluation in newly-diagnosed and recurrent high-grade glioma. Neuroradiology 68(6):1687-1698, 2026. e-Pub 2026. PMID: 41920333.
- Amol J Ghia, Thomas H Beckham, Laurence D Rhines. Long-term Results From a Phase 1 Study of Spinal Cord Constraint Relaxation With Single Session Spine Stereotactic Radiosurgery in the Primary Management of Patients With Inoperable, Previously Unirradiated Spinal Metastases With Epidural Extension. Int J Radiat Oncol Biol Phys 124(5):1219-1225, 2026. PMID: 40614786.
- Haisraely, O, Tom, MC, Perni, S, Kudchadker, RJ, Prajapati, S, Zlateva, Y, Weinberg, JS, Yeboa, DN, Li, J, Ferguson, SD, Alvarez-Breckenridge, C, Patel, CB, Ene, CI, Prabhu, S, Beckham, TH. Cs-131 Collagen Tile Brachytherapy for Recurrent Glioblastoma. Practical radiation oncology 16(2):e101-e107, 2026. e-Pub 2026. PMID: 41360286.
- Beckham TH, Jing Li. Incorporating an NCCN-Based Systemic Therapy CNS Activity Score Into SRS Decision-Making for Patients With 5 or More Brain Metastases. J Natl Compr Canc Netw 24(2):34-40, 2026. e-Pub 2026. PMID: 41671425.
- Christina Abi Faraj, Beckham TH, Jeffrey S Weinberg. Ventricular entry and postoperative leptomeningeal metastasis after resection of supratentorial high-grade glioma. J Neurosurg 144(6):1438-1452, 2026. PMID: 41687103.
- Troy J Kleber, Beckham TH. Outcomes of patients with melanoma brain metastases treated with ipilimumab and nivolumab with or without upfront comprehensive stereotactic radiosurgery. Neurooncol Adv , 2026. PMID: 41664820.
- Haisraely O, Tom MC, Perni S, Kudchadker R, Prajapati S, Zlateva Y, Weinberg JS, Yeboa D, Li J, Ferguson SD, Alvarez-Breckenridge C, Patel CB, Ene CI, Prabhu S, Beckham TH. Cs-131 Collagen Tile Brachytherapy for Recurrent Glioblastoma: Treatment Outcomes and Toxicity. PRO, 2026. e-Pub 2025.
- Yeboa, DN, Whitfield, BT, Lin, R, Ejezie, CL, Swanson, T, Beckham, TH, Wang, C, De, BS, Perni, S, Tom, MC, Li, J, McGovern, SL, Harrison, R, Majd, NK, Puduvalli, VK, Aaroe, AE, Loghin, ME, O'Brien, BJ, Patel, AD, Patel, C, Wefel, JS, Taslicay, CA, Gule-Monroe, MK, Paulino, AC, McAleer, MF, Grosshans, DR, Ghia, AJ, Jiang, W, Chung, C, Maor, MM, Yang, CH, Gubbiotti, M, Kamiya Matsuoka, C, Ballester, L, Weathers, S, Huse, J. Prospective phase II clinical trial of molecular glioblastoma (historical grade 2 and 3 IDH wildtype gliomas) preliminary novel exploratory analyses. Journal of neuro-oncology 176(1), 2026. e-Pub 2026. PMID: 41191157.
- Kleber, T, Milton, D, Srinivasan, S, Panthi, B, Floyd, W, Goethe, E, Davies, MA, Tawbi, H, Glitza, IC, Kaya, D, Li, J, Swanson, T, Perni, S, Tom, MC, Wang, C, Prabhu, SS, Weinberg, J, McCutcheon, IE, Chung, C, Ferguson, SD, Beckham, TH. Outcomes of patients with melanoma brain metastases treated with ipilimumab and nivolumab with or without upfront comprehensive stereotactic radiosurgery. Neuro-Oncology Advances 8(1), 2026. e-Pub 2026. PMID: 41664820.
- Beckham TH, Cha EE, Rooney MK, Tom MC, Perni S, McAleer MF, Li J, Kudchadker RJ, Prajapati S, Zlateva Y, Kaya D, Ene CI, Ferguson SD, Huse JT, Prabhu SS, Weinberg JS. Cesium-131 collagen tile brachytherapy for salvage of recurrent intracranial metastases. J Neurooncol 175(1):165-174, 2025. e-Pub 2025. PMID: 40549120.
- Haisraely, O, Vedala, S, Al-Sharfeen, A, Manzar, G, Perni, S, Tom, MC, Beckham, TH, Wang, C, Yeboa, DN, Chung, C, McAleer, MF, Ghia, AJ, Ene, CI, Weathers, S, McGovern, SL, Wogan, CF, Roth, M, Li, J, De, BS. Glioblastoma in young adult patients. Journal of neuro-oncology 175(1):323-331, 2025. e-Pub 2025. PMID: 40663309.
- Goethe EA, Andrade de Almeida RA, Call-Orellana F, Mikula AL, Clarke MJ, Merrell KW, Rose PS, Karim SM, Linzey JR, Szerlip NJ, Amini B, Beckham TH, Ghia AJ, Li J, Tom MC, McAleer MF, Perni S, Wang C, Yeboa DN, Price A, Alvarez-Breckenridge C, Rhines LD, Tatsui CE, North RY. Sacral fracture risk after stereotactic spinal radiosurgery: a multi-institution, retrospective analysis. J Neurosurg Spine 43(3):305-312, 2025. e-Pub 2025. PMID: 40540799.
- Ding, Y, Salzillo, TC, Yeboa, DN, Tom, MC, Wang, Z, Diagaradjane, P, Subashi, ED, Yang, J, Swanson, T, Beckham, TH, Wang, C, Ghia, AJ, Briere, TM, Wang, J, Lathuilière, F, Cloake, S, Han, EY. Optimizing Motion Management and Baseline Shifts in Magnetic Resonance-Guided Spine Stereotactic Body Radiation Therapy. Cancers 17(16), 2025. e-Pub 2025. PMID: 40867326.
- Zhang, B, Shah, K, Parma, M, Wang, K, Singhi, EK, Lewis, WE, Rivera, MJ, Altan, M, Pozadzides, JV, Le, X, Vokes, N, Fossella, FV, O'Brien, BJ, Wang, C, Tom, MC, Beckham, TH, Swanson, T, Bronk, JK, Lin, SH, Vega, MF, Jacome, J, Halliday, A, Vailati Negrao, M, Zhang, J, Gibbons, DL, Heymach, JV, Byers, LA, Gay, CM. Rapid Intracranial Response With Tarlatamab in Patients With Untreated Brain Metastases From SCLC—A Real-World Case Series. Journal of Thoracic Oncology 20(8):1131-1138, 2025. e-Pub 2025. PMID: 40126456.
- Yeboa DN, Li J, Lin R, Prabhu SS, Beckham TH, Woodhouse K, Swanson TA, Weinberg JS, Wang X, Chi X, Ejezie CL, Suki D, Wang C, Ene C, McCutcheon IE, McGovern S, McAleer MF, Tom M, Ghia A, Perni S, Jiang W, De B, Chung C, Kim BYS, O'Brien BJ, Huse JT, Wefel JS, Court L, Tawbi H, Janku F, Guha-Thakurta N, Debnam JM, Johnson J, Taslicay CA, Alvarez-Breckenridge C, Raza SM, Heimberger AB, DeMonte F, North R, Briere TM, de Groot JF, Sawaya R, Grosshans D, Lang FF, Rao G, Ferguson SD. Therapy, Safety, and Logistics of Preoperative vs Postoperative Stereotactic Radiation Therapy: A Preliminary Analysis of a Randomized Clinical Trial. JAMA Oncol 11(8):890-899, 2025. e-Pub 2025. PMID: 40531511.
- Andrade-Almeida RA, Call-Orellana F, Zuluaga-Garcia JP, Ramirez-Ferrer E, Kimchi G, De BS, Guimaraes AB, Alvarez-Breckenridge CA, Li J, Ghia AJ, Rhines L, Tom MC, Wang C, Beckham TH, Amini B, North RY, Tatsui CE. Local Control After Adjuvant Radiosurgery for Spinal Metastasis Treated With Decompression and Posterior Segmental Stabilization: A Comparison Between Carbon Fiber/Polyetheretherketone-Based and Metallic Implants. Adv Radiat Oncol 10(7), 2025. e-Pub 2025. PMID: 40548160.
- Matsui, JK, Swanson, DM, Allen, P, Perlow, HK, Bradshaw, J, Beckham, TH, Tom, MC, Wang, C, Perni, S, Yeboa, DN, Ghia, AJ, McAleer, MF, Li, J, Palmer, JD, McGovern, SL. Reduced Treatment Volumes for Glioblastoma Associated With Lower Rates of Radionecrosis and Lymphopenia. Advances in Radiation Oncology 10(3), 2025. e-Pub 2025. PMID: 40028224.
- Lam, K, Nasr, L, Andersen, C, Marqueen, KE, Li, J, Wang, C, Beckham, TH, Majd, NK, Aaroe, AE, Loghin, ME, O'Brien, BJ, McGovern, SL. Early Outcomes from Proton Craniospinal Irradiation for Leptomeningeal Metastasis From Solid Tumors. Advances in Radiation Oncology 10(2), 2025. e-Pub 2025. PMID: 39866593.
- Dudzinski, SO, Cabanillas, ME, Hamidi, S, Marczyk, VR, Busaidy, NL, Dadu, R, Welsh, J, Hu, MI, Gunn, GB, Wang, C, Waguespack, SG, Phan, J, Beckham, TH, Chang, JY, Sherman, SI, Reddy, JP, Ying, AK, O'Reilly, M, Chen, A, Lee, A, Gandhi, S, Liao, Z, Ludmir, EB, Nguyen, Q, Lin, SH, Zafereo, M, Ning, M. Definitive Radiotherapy for Oligometastatic and Oligoprogressive Thyroid Cancer. JNCCN Journal of the National Comprehensive Cancer Network 23(1), 2025. e-Pub 2025. PMID: 39662038.
- Dudzinski, S O, Cabanillas, M E, Hamidi, S, Marczyk, V R, Busaidy, N L, Dadu, R, Welsh, J, Hu, M I, Gunn, G B, Wang, C, Waguespack, S G, Phan, J, Beckham, T H, Chang, J Y, Sherman, S I, Reddy, J P, Ying, A K, O’Reilly, M S, Chen, A, Lee, A, Gandhi, S J, Liao, Z, Ludmir, E B, Nguyen, Q, Lin, S H, Zafereo, M E, Ning, M S. Definitive Radiotherapy for Oligometastatic and Oligoprogressive Thyroid Cancer: A Potential Strategy for Systemic Therapy Deferral. JNCCN, 2024. e-Pub 2024. PMID: 39662038.
- Gallitto M, Sedor G, Lee A, Pasetsky J, Kinslow CJ, Santos GL, Obiri-Yeboah D, Kshettry VR, Helis CA, Chan MD, Beckham TH, McGovern SL, Matsui J, Palmer JD, Bell JB, Mellon EA, Lakomy D, Huang J, Boor I, Rusthoven CG, Sisti MB, Wang TJC. Salvage Stereotactic Radiosurgery for Recurrent WHO Grade 2 and 3 Meningiomas: A Multicenter Study (STORM). Int J Radiat Oncol Biol Phys 120(3):730-737, 2024. e-Pub 2024. PMID: 38641234.
- Tom MC, Komatineni S, Wang C, de Almeida RAA, Ghia AJ, Beckham TH, Perni S, McAleer MF, Swanson T, Yeboa DN, De BS, Rooney MK, Bishop AJ, Reddy JP, Yang Y, Ludmir EB, Zhang S, Amini B, Alvarez-Breckenridge C, North RY, Rhines LD, Li J, Tatsui CE. Spinal laser interstitial thermal therapy and radiotherapy for thoracic metastatic epidural spinal cord compression. J Neurooncol 170(2):289-296, 2024. e-Pub 2024. PMID: 39325339.
- Yadav D, Upadhyay R, Kumar VA, Chen MM, Johnson JM, Langshaw H, Curl BJ, Farhat M, Talpur W, Beckham TH, Yeboa DN, Swanson TA, Ghia AJ, Li J, Chung C. Additive Value of Magnetic Resonance Simulation Before Chemoradiation in Evaluating Treatment Response and Pseudoprogression in High-Grade Gliomas. Pract Radiat Oncol 14(6):e449-e457, 2024. e-Pub 2024. PMID: 38685448.
- Florez MA, De B, Kowalchuk R, Tang C, Bishop AJ, Kouzy R, Amini B, Briere T, Beckham TH, Wang C, Li J, Tatsui CE, Rhines LD, Brown PD, Merrell K, Ghia AJ. Validation of the prognostic index for spine metastasis (PRISM) for stratifying survival in patients treated with spinal stereotactic body radiation. Radiother Oncol 201:110570, 2024. e-Pub 2024. PMID: 39362605.
- Beckham TH, Rooney MK, Cifter G, Bernard V, McAleer MF, De BS, Tom MC, Perni S, Wang C, Swanson T, Tatsui CE, Alvarez-Breckenridge C, North R, Rhines LD, Tang C, Logothetis C, Amini B, Li J, Yeboa DN, Ghia AJ. Stereotactic radiosurgery for prostate cancer spine metastases: local control and fracture risk using a simultaneous integrated boost approach. J Neurosurg Spine 41(3):436-444, 2024. e-Pub 2024. PMID: 38875722.
- Beckham, TH, Dudzinski, SO, Pasli, M, Perni, S, Tom, MC, Ghia, AJ, Yeboa, DN, McAleer, MF, Swanson, T, McGovern, SL, Wang, C, Chung, C, Briere, TM, An, R, De, BS, Glitza, IC, Kim, YB, McCutcheon, IE, Ferguson, SD, Li, J. Radiosurgery to 5 or more newly diagnosed brain metastases in the systemic therapy era. Journal of Clinical Oncology 42(16):2026, 2024. e-Pub 2024.
- Beckham TH, Rooney MK, McAleer MF, Ghia AJ, Tom MC, Perni S, McGovern S, Grosshans D, Chung C, Wang C, De B, Swanson T, Paulino A, Jiang W, Ferguson S, Patel CB, Li J, Yeboa DN. Hypofractionated radiotherapy for glioblastoma: A large institutional retrospective assessment of 2 approaches. Neurooncol Pract 11(3):266-274, 2024. e-Pub 2024. PMID: 38737610.
- Ene CI, Abi Faraj C, Beckham TH, Weinberg JS, Andersen CR, Haider AS, Rao G, Ferguson SD, Alvarez-Brenkenridge CA, Kim BYS, Heimberger AB, McCutcheon IE, Prabhu SS, Wang CM, Ghia AJ, McGovern SL, Chung C, McAleer MF, Tom MC, Perni S, Swanson TA, Yeboa DN, Briere TM, Huse JT, Fuller GN, Lang FF, Li J, Suki D, Sawaya RE. Response of Treatment-Naive Brain Metastases to Stereotactic Radiosurgery. Nat Commun 15(1):3728, 2024. e-Pub 2024. PMID: 38697991.
- Wang C, Rooney MK, Alvarez-Breckenridge C, Beckham TH, Chung C, De BS, Ghia AJ, Grosshans D, Majd NK, McAleer MF, McGovern SL, North RY, Paulino AC, Perni S, Reddy JP, Rhines LD, Swanson TA, Tatsui CE, Tom MC, Yeboa DN, Li J. Outcomes and Pattern of Care for Spinal Myxopapillary Ependymoma in the Modern Era-A Population-Based Observational Study. Cancers (Basel) 16(11), 2024. e-Pub 2024. PMID: 38893133.
- Shanker MD, Cavazos AP, Li J, Beckham TH, Yeboa DN, Wang C, McAleer MF, Briere TM, Amini B, Tatsui CE, North RY, Alvarez-Breckenridge CA, Cezayirli PC, Rhines LD, Ghia AJ, Bishop AJ. Definitive single fraction spine stereotactic radiosurgery for metastatic sarcoma: Simultaneous integrated boost is associated with high tumor control and low vertebral fracture risk. Radiother Oncol 193:110119, 2024. e-Pub 2024. PMID: 38311030.
- Ledbetter D, de Almeida R, Wu X, Naveh A, Patel CB, Gonzalez Q, Beckham TH, North R, Rhines L, Li J, Ghia A, Aten D, Tatsui C, Alvarez-Breckenridge C. Tumor treating fields suppress tumor cell growth and neurologic decline in models of spine metastases. JCI Insight, 2024. e-Pub 2024. PMID: 38512420.
- Katlowitz KA, Beckham TH, Kudchadker RJ, Wefel J, Elamin YY, Weinberg AJ. A Novel Multimodal Approach to Refractory Brain Metastases: A Case Report. Advances in Radiation Oncology 9(2), 2024. e-Pub 2024. PMID: 38405307.
- de Almeida RAA, Ghia AJ, Amini B, Wang C, Alvarez-Breckenridge CA, Li J, Rhines LD, Tom MC, North RY, Beckham TH, Tatsui CE. Quantification of MRI Artifacts in Carbon Fiber Reinforced Polyetheretherketone Thoracolumbar Pedicle Screw Constructs prior to Spinal Stereotactic Radiosurgery. Pract Radiat Oncol 14(2):103-111, 2024. e-Pub 2024. PMID: 37914081.
- Sherry AD, Maroongroge S, De B, Amini B, Conley AP, Bishop AJ, Wang C, Beckham T, Tom M, Briere T, Li J, Yeboa DN, McAleer MF, North R, Tatsui CE, Rhines LD, Ghia AJ. Management of chordoma and chondrosarcoma with definitive dose-escalated single-fraction spine stereotactic radiosurgery. J Neurooncol 164(2):377-386, 2023. e-Pub 2023. PMID: 37667065.
- Dodoo GN, De B, Lee SS, Abi Jaoude J, Vauthey JN, Tzeng CD, Tran Cao HS, Katlowitz KA, Mandel JJ, Beckham TH, Minsky BD, Smith GL, Holliday EB, Koong AC, Das P, Taniguchi CM, Javle M, Koay EJ, Ludmir EB. Brain Metastases from Biliary Tract Cancer: Case Series and Clinicogenomic Analysis. Oncologist 28(4):327-332, 2023. e-Pub 2023. PMID: 36715178.
- Florez MA, De B, Cavazos A, Farooqi A, Beckham TH, Wang C, Yeboa DN, Bishop AJ, McAleer MF, Briere T, Amini B, Li J, Tatsui CE, Rhines LD, Ghia AJ. Safety and Efficacy of Dose-Escalated Radiation Therapy With a Simultaneous Integrated Boost for the Treatment of Spinal Metastases. Pract Radiat Oncol 13(1):e7-e13, 2023. e-Pub 2023. PMID: 36604100.
- Beckham TH, Yang JC, Chau KW, Noy A, Yahalom J. Excellent Outcomes with Surgery or Radiotherapy in the Management of Castleman Disease Including a Case of Oligocentric Disease. Clin Lymphoma Myeloma Leuk 20(10):685-689, 2020. e-Pub 2020. PMID: 32522439.
- Beckham TH, Barney C, Healy E, Wolfe AR, Branstetter A, Yaney A, Riaz N, McBride SM, Tsai CJ, Kang J, Yu Y, Chen L, Sherman E, Dunn L, Pfister DG, Tan J, Rupert R, Bonomi M, Zhang Z, Lobaugh SM, Grecula JC, Mitchell DL, Wobb JL, Miller ED, Blakaj DM, Diavolitsis VM, Lee N, Bhatt AD. Platinum-based regimens versus cetuximab in definitive chemoradiation for human papillomavirus-unrelated head and neck cancer. Int J Cancer 147(1):107-115, 2020. e-Pub 2020. PMID: 31609479.
- Groen AH, Beckham TH, Links TP, Goldman DA, Sherman EJ, Tuttle MM, Bijl HP, Wong RJ, Plukker JTM, Lee NY, Group/Consortium Members AO. Outcomes of surgery and postoperative radiation therapy in managing medullary thyroid carcinoma. J Surg Oncol, 2020. e-Pub 2020. PMID: 31733124.
- Beckham TH, Leeman JE, Xie P, Li X, Goldman DA, Zhang Z, Sherman E, McBride S, Riaz N, Lee N, Tsai CJ. Long-term survival in patients with metastatic head and neck squamous cell carcinoma treated with metastasis-directed therapy. Br J Cancer 121(11):897-903, 2019. e-Pub 2019. PMID: 31649318.
- Zhang J, Srivastava S, Wang C, Beckham TH, Johnson C, Dutta P, Shepherd A, Mechalakos J, Hunt M, Wu A, Rimner A, Li G. Clinical evaluation of 4D MRI in the delineation of gross and internal tumor volumes in comparison with 4DCT. J Appl Clin Med Phys 20(9):51-60, 2019. e-Pub 2019. PMID: 31538719.
- Beckham TH, Imber BS, Simone CB. Stereotactic body radiation therapy for oligometastatic renal cell carcinoma: improving outcomes in an otherwise radioresistant malignancy. Ann Transl Med 7(Suppl 3):S98, 2019. e-Pub 2019. PMID: 31576305.
- Beckham TH, Leeman J, Jillian Tsai C, Riaz N, Sherman E, Singh B, Lee N, McBride S, Higginson DS. Treatment modalities and outcomes of Fanconi anemia patients with head and neck squamous cell carcinoma: Series of 9 cases and review of the literature. Head Neck 41(5):1418-1426, 2019. e-Pub 2019. PMID: 30633423.
- Beckham TH, Romesser PB, Groen AH, Sabol C, Shaha AR, Sabra M, Brinkman T, Spielsinger D, McBride S, Tsai CJ, Riaz N, Tuttle RM, Fagin JA, Sherman EJ, Wong RJ, Lee NY. Intensity-Modulated Radiation Therapy With or Without Concurrent Chemotherapy in Nonanaplastic Thyroid Cancer with Unresectable or Gross Residual Disease. Thyroid 28(9):1180-1189, 2018. e-Pub 2018. PMID: 30105947.
- Orwat KP, Beckham TH, Cooper SL, Ashenafi MS, Anderson MB, Guimaraes M, Yamada R, Marshall DT. Pretreatment albumin may aid in patient selection for intrahepatic Y-90 microsphere transarterial radioembolization (TARE) for malignancies of the liver. J Gastrointest Oncol 8(6):1072-1078, 2017. e-Pub 2017. PMID: 29299369.
- Beckham TH, Casey DL, LaQuaglia MP, Kushner BH, Modak S, Wolden SL. Renal Function Outcomes of High-risk Neuroblastoma Patients Undergoing Radiation Therapy. Int J Radiat Oncol Biol Phys 99(2):486-493, 2017. e-Pub 2017. PMID: 28872000.
- Price ST, Beckham TH, Cheng JC, Lu P, Liu X, Norris JS. Sphingosine 1-Phosphate Receptor 2 Regulates the Migration, Proliferation, and Differentiation of Mesenchymal Stem Cells. Int J Stem Cell Res Ther 2(2), 2015. e-Pub 2015. PMID: 27275017.
- Cheng JC, Bai A, Beckham TH, Marrison ST, Yount CL, Young K, Lu P, Bartlett AM, Wu BX, Keane BJ, Armeson KE, Marshall DT, Keane TE, Smith MT, Jones EE, Drake RR, Bielawska A, Norris JS, Liu X. Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse. J Clin Invest 123(10):4344-58, 2013. e-Pub 2013. PMID: 24091326.
- Beckham TH, Cheng JC, Lu P, Shao Y, Troyer D, Lance R, Marrison ST, Norris JS, Liu X. Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling. Oncogenesis 2:e49, 2013. e-Pub 2013. PMID: 23732709.
- Beckham TH, Lu P, Jones EE, Marrison T, Lewis CS, Cheng JC, Ramshesh VK, Beeson G, Beeson CC, Drake RR, Bielawska A, Bielawski J, Szulc ZM, Ogretmen B, Norris JS, Liu X. LCL124, a cationic analog of ceramide, selectively induces pancreatic cancer cell death by accumulating in mitochondria. J Pharmacol Exp Ther 344(1):167-78, 2013. e-Pub 2013. PMID: 23086228.
- Beckham TH, Cheng JC, Lu P, Marrison ST, Norris JS, Liu X. Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling. PLoS One 8(10):e76593, 2013. e-Pub 2013. PMID: 24098536.
- Beckham TH, Lu P, Cheng JC, Zhao D, Turner LS, Zhang X, Hoffman S, Armeson KE, Liu A, Marrison T, Hannun YA, Liu X. Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B. Int J Cancer 131(9):2034-43, 2012. e-Pub 2012. PMID: 22322590.
- Turner LS, Cheng JC, Beckham TH, Keane TE, Norris JS, Liu X. Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide. Prostate Cancer Prostatic Dis 14(1):30-7, 2011. e-Pub 2011. PMID: 21116286.
- Mahdy AE, Cheng JC, Li J, Elojeimy S, Meacham WD, Turner LS, Bai A, Gault CR, McPherson AS, Garcia N, Beckham TH, Saad A, Bielawska A, Bielawski J, Hannun YA, Keane TE, Taha MI, Hammouda HM, Norris JS, Liu X. Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer. Mol Ther 17(3):430-8, 2009. e-Pub 2009. PMID: 19107118.
- Wang X, Beckham TH, Morris JC, Chen F, Gangemi JD. Bioactivities of gossypol, 6-methoxygossypol, and 6,6'-dimethoxygossypol. J Agric Food Chem 56(12):4393-8, 2008. e-Pub 2008. PMID: 18517219.
Review Articles
- Bahouth SM, Yeboa DN, Ghia AJ, Tatsui CE, Alvarez-Breckenridge CA, Beckham TH, Bishop AJ, Li J, McAleer MF, North RY, Rhines LD, Swanson TA, Chenyang W, Amini B. Advances in the management of spinal metastases: what the radiologist needs to know. Br J Radiol 96(1141):20220267, 2023. e-Pub 2023. PMID: 35946551.
- Yarabarla V, Mylarapu A, Han TJ, McGovern SL, Raza SM, Beckham TH. Intracranial meningiomas: an update of the 2021 World Health Organization classifications and review of management with a focus on radiation therapy. Front Oncol 13(13):1137849, 2023. e-Pub 2023. PMID: 37675219.
- Bahouth SM, Yeboa DN, Ghia AJ, Tatsui CE, Alvarez-Breckenridge CA, Beckham TH, Bishio AJ, Li J, McAleer MF, North RY, Rhines LD, Swanson TA, Chenyang W, Amini B. Multidisciplinary management of spinal metastases: what the radiologist needs to know. Br J Radiol 95(1138):20220266, 2022. e-Pub 2022. PMID: 35856792.
- Hasanov E, Yeboa DN, Tucker MD, Swanson TA, Beckham TH, Rini B, Ene CI, Hasanov M, Derks S, Smits M, Dudani S, Heng DYC, Brastianos PK, Bex A, Hanalioglu S, Weinberg JS, Hirsch L, Carlo MI, Aizer A, Brown PD, Bilen MA, Chang EL, Jaboin J, Brugarolas J, Choueiri TK, Atkins MB, McGregor BA, Halasz LM, Patel TR, Soltys SG, McDermott DF, Elder JB, Baskaya MK, Yu JB, Timmerman R, Kim MM, Mut M, Markert J, Beal K, Tannir NM, Samandouras G, Lang FF, Giles R, Jonasch E. An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma. CA Cancer J Clin 72(5):454-489, 2022. e-Pub 2022. PMID: 35708940.
- Beckham TH, Yang TJ, Gomez D, Tsai CJ. Metastasis-directed therapy for oligometastasis and beyond. Br J Cancer 124(1):136-141, 2021. e-Pub 2021. PMID: 33204024.
- Beckham TH, Cheng JC, Marrison ST, Norris JS, Liu X. Interdiction of sphingolipid metabolism to improve standard cancer therapies. Adv Cancer Res 117:1-36, 2013. e-Pub 2013. PMID: 23290775.
- Beckham TH, Elojeimy S, Cheng JC, Turner LS, Hoffman SR, Norris JS, Liu X. Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials. Expert Opin Ther Targets 14(5):529-39, 2010. e-Pub 2010. PMID: 20334489.
- Liu X, Cheng JC, Turner LS, Elojeimy S, Beckham TH, Bielawska A, Keane TE, Hannun YA, Norris JS. Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy. Expert Opin Ther Targets 13(12):1449-58, 2009. e-Pub 2009. PMID: 19874262.
Abstracts
- Jeffrey S. Weinberg, Thomas Hendrix Beckham. Central Nervous System Tumors. 2026 ASCO Annual Meeting.
Book Chapters
- Beckham TH. Brain Mets Management. In: Pocket Radiation Oncology. 2. Wolters Kluwer Health, 2024.
Patient Reviews
CV information above last modified September 23, 2026