Tina Marie Briere, Ph.D., DABR
Department of Radiation Physics, Division of Radiation Oncology
Present Title & Affiliation
Primary Appointment
Professor, Department of Radiation Physics - Patient Care, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Member, Graduate School of Biomedical Sciences, University of Texas, Houston, TX
Education & Training
Degree-Granting Education
| 1995 | State University of New York at Albany, Albany, NY, USA, PHD, Physics |
| 1988 | Rensselaer Polytechnic Institute, Troy, NY, USA, BS, Physics |
Board Certifications
| 2009 | American Board of Radiology, Therapeutic Radiologic Physics |
Experience & Service
Academic Appointments
Associate Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2021
Assistant Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009 - 2015
Administrative Appointments/Responsibilities
Gamma Knife Radiation Safety Officer, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - Present
Service Chief, CNS/Pediatrics Service, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - Present
Selected Publications
Peer-Reviewed Articles
- Huang K, Das P, Olanrewaju AM, Cardenas C, Fuentes D, Zhang L, Hancock D, Simonds H, Rhee DJ, Beddar S, Briere TM, Court L. Automation of radiation treatment planning for rectal cancer. J Appl Clin Med Phys 23(9):e13712, 2022. e-Pub 2022. PMID: 35808871.
- Briere TM, Agrusa JE, Martel MK, Jackson A, Olch AJ, Ronckers CM, Kremer LCM, Constine LS, McAleer MF. Acute and Late Pulmonary Effects After Radiation Therapy in Childhood Cancer Survivors: A PENTEC Comprehensive Review. Int J Radiat Oncol Biol Phys S0360-3016(22):00132-00138. e-Pub 2022. PMID: 35525723.
- Han EY, Wang H, Briere TM, Yeboa DN, Boursianis T, Kalaitzakis G, Pappas E, Castillo P, Yang J. Brain stereotactic radiosurgery using MR-guided online adaptive planning for daily setup variation: an end-to-end test. J Appl Clin Med Phys 23(3):e13518, 2022. e-Pub 2022. PMID: 34994101.
- Tang TT, Zawaski JA, Kesler S, Beamish CA, Inoue T, Perez EC, Bronk L, Poenisch F, Briere TM, Sabek OM, Grosshans DR, Waleed Gaber M. Cognitive and Imaging Differences After Proton and Photon Whole Brain Irradiation in a Preclinical Model. Int J Radiat Oncol Biol Phys 112(2):554-564, 2022. e-Pub 2021. PMID: 34509550.
- Han EY, Cardenas CE, Nguyen C, Hancock D, Xiao Y, Mumme R, Court LE, Rhee DJ, Netherton TJ, Li J, Yeboa DN, Wang C, Briere TM, Balter P, Martel MK, Wen Z. Clinical implementation of automated treatment planning for whole-brain radiotherapy. J Appl Clin Med Phys 22(9):94-102, 2021. PMID: 34250715.
- Thrower SL, Al Feghali KA, Luo D, Paddick I, Hou P, Briere T, Li J, McAleer MF, McGovern SL, Woodhouse KD, Yeboa DN, Brock KK, Chung C. The Effect of Slice Thickness on Contours of Brain Metastases for Stereotactic Radiosurgery. Adv Radiat Oncol 6(4):100708, 2021. e-Pub 2021. PMID: 34124413.
- Pollard-Larkin JM, Briere TM, Kudchadker RJ, Sadagopan R, Nitsch PL, Wang XA, Salehpour M, Wang J, Vedam S, Nelson CL, Sahoo N, Zhu XR, Court LE, Balter PA, Robinson IJ, Yang J, Howell RM, Followill DS, Kry S, Beddar SA, Martel MK. Our Experience Leading a Large Medical Physics Practice During the COVID-19 Pandemic. Adv Radiat Oncol 6(4):100683, 2021. e-Pub 2021. PMID: 33824935.
- Ning MS, Das P, Rosenthal DI, Dabaja BS, Liao Z, Chang JY, Gomez DR, Klopp AH, Gunn GB, Allen PK, Nitsch PL, Natter RB, Briere TM, Herman JM, Wells R, Koong AC, McAleer MF. Early and mid-treatment mortality in palliative radiotherapy: Emphasizing patient selection in high-quality end-of-life care. J Natl Compr Canc Netw 19(7):1-9, 2021. e-Pub 2021. PMID: 33878727.
- Zhou Z, Sanders JW, Johnson JM, Gule-Monroe M, Chen M, Briere TM, Wang Y, Son JB, Pagel MD, Ma J, Li J. MetNet: Computer-aided segmentation of brain metastases in post-contrast T1-weighted magnetic resonance imaging. Radiother Oncol 153:189-196, 2020. e-Pub 2020. PMID: 32937104.
- Diao K, Song J, Thall PF, McGinnis GJ, Boyce-Fappiano D, Amini B, Brown PD, Yeboa DN, Bishop AJ, Li J, Briere TM, Tatsui CE, Rhines LD, Chang EL, Ghia AJ. Low risk of radiation myelopathy with relaxed spinal cord dose constraints in de novo, single fraction spine stereotactic radiosurgery. Radiother Oncol 152:49-55, 2020. e-Pub 2020. PMID: 32745668.
- Han EY, Diagaradjane P, Luo D, Ding Y, Kalaitzakis G, Zoros E, Zourari K, Boursianis T, Pappas E, Wen Z, Wang J, Briere TM. Validation of PTV margin for Gamma Knife Icon frameless treatment using a PseudoPatient® Prime anthropomorphic phantom. J Appl Clin Med Phys. e-Pub 2020. PMID: 32786141.
- Baltz GC, Briere T, Luo D, Howell RM, Krafft S, Han EY. 3D-Printed Headrest for Frameless Gamma Knife Radiosurgery: Design and Validation. J Appl Clin Med Phys. e-Pub 2020. PMID: 32603542.
- Gjyshi O, Boyce-Fappiano D, Pezzi TA, Ludmir EB, Xiao L, Kaseb A, Amini B, Yeboa DN, Bishop AJ, Li J, Rhines LD, Tatsui CE, Briere TM, Ghia AJ. Spine Stereotactic Radiosurgery for Metastases from Hepatobiliary Malignancies: Patient Selection using PRISM Scoring. J Neurooncol 148(2):327-334, 2020. e-Pub 2020. PMID: 32358642.
- Luo D, Han EY, Wen Z, Mackin DS, Krafft SP, Li J, Wang X, Briere TM. Use of uniform shots for robust planning of mask-based treatment in Gamma Knife Icon. Phys Med 73:135-157, 2020. e-Pub 2020. PMID: 32361402.
- Zhou Z, Sanders JW, Johnson JM, Gule-Monroe MK, Chen MM, Briere TM, Wang Y, Son JB, Pagel MD, Li J, Ma J. Computer-aided Detection of Brain Metastases in T1-weighted MRI for Stereotactic Radiosurgery Using Deep Learning Single-Shot Detectors. Radiology 295(2):407-415, 2020. e-Pub 2020. PMID: 32181729.
- Boyce-Fappiano D, Gjyshi O, Pezzi TA, Allen PK, Solimman M, Taku N, Bernstein MB, Cabanillas ME, Amini B, Tatsui CE, Rhines LD, Wang XA, Briere TM, Yeboa DN, Bishop AJ, Li J, Ghia AJ. Spine Stereotactic Radiosurgery for Metastatic Thyroid Cancer: A Single Institution Experience. J Neurosurg Spine:1-9. e-Pub 2020. PMID: 32059183.
- Han EY, Aima M, Hughes M, Briere TM, Yeboa DN, Castillo P, Wang J, Yang J, Vedam S. Feasibility study for spine SBRT in MR-Linac. J Radiosurg SBRT 7(2):127-134, 2020. PMID: 33282466.
- Ning MS, Deegan BJ, Ho JC, Chapman BV, Bishop AJ, Allen PK, Tannir NM, Amini B, Briere TM, Wang XA, Tatsui CE, Rhines LD, Brown PD, Li J, Ghia AJ. Low incidence of late failure and toxicity after spine stereotactic radiosurgery: Secondary analysis of phase I/II trials with long-term follow-up. Radiother Oncol 138:80-85, 2019. e-Pub 2019. PMID: 31252298.
- Traylor JI, Habib A, Patel R, Muir M, Gadot R, Briere T, Yeboa DN, Li J, Rao G. Fractionated stereotactic radiotherapy for local control of resected brain metastases. J Neurooncol 144(2):343-350, 2019. e-Pub 2019. PMID: 31313060.
- Han EY, Kim GY, Rebueno N, Yeboa DN, Briere TM. End-to-end testing of automatic plan optimization using RayStation scripting for hypofractionated multi-metastatic brain stereotactic radiosurgery. Med Dosim 44(4):e44-e50, 2019. e-Pub 2019. PMID: 30655170.
- Sheu T, Briere TM, Olanrewaju AM, McAleer MF. Intensity Modulated Radiation Therapy Versus Volumetric Arc Radiation Therapy in the Treatment of Glioblastoma-Does Clinical Benefit Follow Dosimetric Advantage?. Adv Radiat Oncol 4(1):50-56, 2019. e-Pub 2018. PMID: 30706010.
- Han EY, Luo D, Kim JO, Tharp K, Wen Z, and Briere TM. Dosimetric validation of the Gamma Knife Icon plan adaptation and high-definition motion management system with a motorized anthropomorphic head phantom. J Radiosurg SBRT 6.3(217-226), 2019.
- Ayala GB, Doan KA, Ko HJ, Park PK, Santiago ED, Kuruvila SJ, Ghia AJ, Briere TM, Wen Z. IMRT planning parameter optimization for spine stereotactic radiosurgery. Med Dosim 44(4):303-308, 2019. e-Pub 2018. PMID: 30514600.
- Jensen GL, Wu H, Luo D, Ho JC, Allen PK, Briere TM, Brown PD, Li J. Use of three pins in Gamma Knife stereotactic radiosurgery for brain metastases. J Radiosurg SBRT 6:209-216, 2019.
- Krafft SP, Rao A, Stingo F, Briere TM, Court LE, Liao Z, Martel MK. The utility of quantitative CT radiomics features for improved prediction of radiation pneumonitis. Med Phys 45(11):5317-5324, 2018. e-Pub 2018. PMID: 30133809.
- Niedzielski JS, Yang J, Mohan R, Titt U, Mirkovic D, Stingo F, Liao Z, Gomez DR, Martel MK, Briere TM, Court LE. Differences in Normal Tissue Response in the Esophagus Between Proton and Photon Radiation Therapy for Non-Small Cell Lung Cancer Using In Vivo Imaging Biomarkers. Int J Radiat Oncol Biol Phys 99(4):1013-1020, 2017. e-Pub 2017. PMID: 29063837.
- Niedzielski JS, Yang J, Stingo F, Liao Z, Gomez D, Mohan R, Martel M, Briere T, Court L. A Novel Methodology using CT Imaging Biomarkers to Quantify Radiation Sensitivity in the Esophagus with Application to Clinical Trials. Sci Rep 7(1):6034, 2017. e-Pub 2017. PMID: 28729729.
- Briere TM, McAleer MF, Levy LB, Yang JN. Sparing of normal tissues with volumetric arc radiation therapy for glioblastoma: single institution clinical experience. Radiat Oncol 12(1):79, 2017. e-Pub 2017. PMID: 28464840.
- Niedzielski JS, Yang J, Liao Z, Gomez DR, Stingo F, Mohan R, Martel MK, Briere TM, Court LE. 18F-Fluorodeoxyglucose Positron Emission Tomography Can Quantify and Predict Esophageal Injury During Radiation. Int J Radiat Oncol Biol Phys 96(3):670-678, 2016. e-Pub 2016. PMID: 27681764.
- Osborne EM, Briere TM, Hayes-Jordan A, Levy LB, Huh WW, Mahajan A, Anderson P, McAleer MF. Survival and Toxicity following Sequential Multimodality Treatment including Whole Abdominopelvic Radiotherapy for Patients with Desmoplastic Small Round Cell Tumor. Radiother Oncol 119(1):40-44, 2016. e-Pub 2015. PMID: 26527430.
- Briere TM, Krafft S, Liao Z, Martel MK. Lung size and the risk of radiation pneumonitis. Int J Radiat Oncol Biol Phys 94(2):377-384, 2016. e-Pub 2015. PMID: 26675062.
- Niedzielski JS, Yang J, Stingo F, Martel MK, Mohan R, Gomez DR, Briere TM, Liao Z, Court LE. Objectively Quantifying Radiation Esophagitis with Novel CT-based In-vivo Metrics. Int J Radiat Oncol Biol Phys 94(2):385-393, 2016. e-Pub 2015. PMID: 26675063.
- Wang X, Ghia AJ, Zhao Z, Yang J, Luo D, Briere TM, Pino R, Li J, McAleer MF, Weksberg DC, Chang EL, Brown PD, Yang JN. Prospective evaluation of target and spinal cord motion and dosimetric changes with respiration in spinal stereotactic body radiation therapy utilizing 4-D CT. J Radiosurg SBRT 4(3):191-201, 2016. PMID: 29296444.
- Kelly P, Das P, Pinnix CC, Beddar S, Briere T, Pham M, Krishnan S, Delclos ME, Crane CH. Duodenal toxicity after fractionated chemoradiation for unresectable pancreatic cancer. Int J Radiat Oncol Biol Phys 85(3):e143-e149, 2013. e-Pub 2012. PMID: 23200173.
- Klein D, Briere TM, Kudchadker R, Archambault L, Beaulieu L, Lee A, Beddar S. In-phantom dose verification of prostate IMRT and VMAT deliveries using plastic scintillation detectors. Radiat Meas 47(10):921-929, 2012. e-Pub 2012. PMID: 23180976.
- Briere TM, Crane CH, Beddar S, Bhosale P, Mok H, Delclos ME, Krishnan S, Das P. Reproducibility and genital sparing with a vaginal dilator used for female anal cancer patients. Radiother Oncol 104(2):161-166, 2012. e-Pub 2012. PMID: 22841019.
- Chakravarty T, Crane CH, Ajani JA, Mansfield PF, Briere TM, Beddar AS, Mok H, Reed VK, Krishnan S, Delclos ME, Das P. Intensity modulated radiation therapy with concurrent chemotherapy as preoperative treatment for localized gastric adenocarcinoma. Int J Radiat Oncol Biol Phys 83(2):581-586, 2012. e-Pub 2011. PMID: 22137021.
- Mok H, Briere TM, Martel MK, Beddar S, Delclos ME, Krishnan S, Crane CH, Das P. Comparative analysis of volumetric modulated arc therapy (VMAT) versus intensity modulated radiation therapy (IMRT) for radiotherapy of anal carcinoma. Pract Radiat Oncol 1(3):163-172, 2011. e-Pub 2011. PMID: 24673946.
- Mok H, Crane CH, Palmer MB, Briere TM, Beddar S, Delclos ME, Krishnan S, Das P. Intensity modulated radiation therapy (IMRT): Differences in target volumes and improvement in clinically relevant doses to small bowel in rectal carcinoma. Radiat Oncol 6:63, 2011. e-Pub 2011. PMID: 21651775.
- Therriault-Proulx F, Briere TM, Mourtada F, Aubin S, Beddar S, Beaulieu L. A Phantom Study of an In Vivo Dosimetry System Using Plastic Scintillation Detectors for Real-Time Verification of 192Ir HDR Brachytherapy. Med Phys 38(5):2542-2551, 2011. PMID: 21776789.
- Therriault-Proulx F, Beddar S, Briere TM, Archambault L, Beaulieu L. Removing the stem effect when performing Ir-192 HDR brachytherapy in vivo dosimetry using plastic scintillation detectors: a relevant and necessary step. Med Phys 38(4):2176-2179, 2011. PMID: 21626951.
- Klein DM, Therriault-Proulx F, Archambault L, Briere TM, Beaulieu L, Beddar AS. Determining regions of interest for CCD camera-based fiber optic luminescence dosimetry by examining signal-to-noise ratio. Med Phys 38(3):1374-1377, 2011. PMID: 21520848.
- Archambault L, Briere TM, Pönisch F, Beaulieu L, Kuban DA, Lee A, Beddar S. Toward a real-time in vivo dosimetry system using plastic scintillation detectors. Int J Radiat Oncol Biol Phys 78(1):280-287, 2010. e-Pub 2010. PMID: 20231074.
- Bouchard M, Amos RA, Briere TM, Beddar S, Crane CH. Dose escalation with proton or photon radiation treatment for pancreatic cancer. Radiother Oncol 92(2):238-243, 2009. e-Pub 2009. PMID: 19454367.
- Briere TM, Beddar S, Balter P, Murthy R, Gupta S, Nelson C, Starkschall G, Gillin MT, Krishnan S. Respiratory gating with EPID-based verification: the MDACC experience. Phys Med Biol 54(11):3379-3391, 2009. e-Pub 2009. PMID: 19436104.
- Pönisch F, Archambault L, Briere TM, Sahoo N, Mohan R, Beddar S, Gillin MT. Liquid scintillator for 2D dosimetry for high-energy photon beams. Med Phys 36(5):1478-1485, 2009. PMID: 19544763.
- Briere TM, Tailor R, Tolani N, Prado K, Lane R, Woo S, Ha C, Gillin MT, Beddar AS. Patient dosimetry for total body irradiation using single-use MOSFET detectors. J Appl Clin Med Phys 9(4):200-205, 2008. e-Pub 2008. PMID: 19020482.
- Archambault L, Briere TM, Beddar S. Transient noise characterization and filtration in CCD cameras exposed to stray radiation from a medical linear accelerator. Med Phys 35(10):4342-4351, 2008. PMID: 18975680.
- Nelson C, Balter P, Morice RC, Choi B, Kudchadker RJ, Bucci K, Chang JY, Dong L, Tucker S, Vedam S, Briere T, Starkschall G. A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials. J Appl Clin Med Phys 9(4):110-122, 2008. e-Pub 2008. PMID: 19020478.
- Wang H, Krishnan S, Wang X, Beddar AS, Briere TM, Crane CH, Mohan R, Dong L. Improving soft tissue contrast in 4D CT images for liver cancer patients using deformable image registration method. Int J Radiat Oncol Biol Phys 72(1):201-209, 2008. PMID: 18722271.
- Beddar AS, Briere TM, Balter P, Pan T, Tolani N, Ng C, Szklaruk J, Krishnan S. 4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning. Radiother Oncol 87(3):445-448, 2008. e-Pub 2008. PMID: 18194819.
- Krishnan S, Dawson LA, Seong J, Akine Y, Beddar S, Briere TM, Crane CH, Mornex F. Radiotherapy for hepatocellular carcinoma: An overview. Ann Surg Oncol 15(4):1015-1024, 2008. e-Pub 2008. PMID: 18236114.
- Wang X, Krishnan S, Zhang X, Dong L, Briere T, Crane CH, Martel M, Gillin M, Mohan R, Beddar S. Proton radiotherapy for liver tumors: Dosimetric advantages over photon plans. Med Dosim 33(4):259-267, 2008. PMID: 18973852.
- Briere TM, Gillin MT, Beddar AS. Implantable MOSFET detectors: Evaluation of a new design. Med Phys 34(12):4585-4590, 2007. PMID: 18196784.
- Krishnan S, Briere TM, Dong L, Murthy R, Ng C, Balter P, Mohan R, Gillin MT, Beddar AS. Daily targeting of liver tumors: Screening patients with a mock treatment and using a combination of internal and external fiducials for image-guided respiratory-gated radiotherapy. Med Phys 34(12):4591-4593, 2007. PMID: 18196785.
- Beddar AS, Kainz K, Briere TM, Tsunashima Y, Pan T, Prado K, Mohan R, Gillin M, Krishnan S. Correlation between internal-fiducial tumor motion and external-marker motion for liver tumors imaged with 4D-CT. Int J Radiat Oncol Biol Phys 67(2):630-638, 2007. PMID: 17236980.
- Krishnan S, Lin EH, Gunn GB, Chandra A, Beddar AS, Briere TM, Das P, Delclos ME, Janjan NA, Crane CH. Conformal radiotherapy of dominant liver metastasis: A viable strategy for treatment of unresectable chemotherapy refractory colorectal cancer liver metastases. Am J Clin Oncol 29(6):562-567, 2006. PMID: 17148992.
- Beddar AS, Briere TM, Ouzidane M. Intraoperative radiation therapy using a mobile electron linear accelerator: Field matching for large-field electron irradiation. Phys Med Biol 51(18):N331-N337, 2006. e-Pub 2006. PMID: 16953035.
- Briere TM, Lii J, Prado K, Gillin MT, Sam Beddar A. Single-use MOSFET radiation dosimeters for the quality assurance of megavoltage photon beams. Phys Med Biol 51(5):1139-1144, 2006. e-Pub 2006. PMID: 16481683.
- Beddar AS, Krishnan S, Briere TM, Wang X, Delclos ME, Ballo MT, Das P, Gould S, Horton JL, Crane CH. The optimization of dose delivery for intraoperative high-dose-rate radiation therapy using curved HAM applicators. Radiother Oncol 78(2):207-212, 2006. e-Pub 2006. PMID: 16376445.
- Briere TM, Beddar AS, Gillin MT. Evaluation of pre-calibrated implantable MOSFET radiation dosimeters for megavoltage photon beams. Med Phys 32(11):3346-3349, 2005. PMID: 16370421.
- Beddar AS, Briere TM, Mourtada FA, Vassiliev ON, Liu HH, Mohan R. Monte Carlo calculations of the absorbed dose and energy dependence of plastic scintillators. Med Phys 32(5):1265-1269, 2005. PMID: 15984678.
- Beddar AS, Salehpour M, Briere TM, Hamidian H, Gillin MT. Preliminary evaluation of implantable MOSFET radiation dosimeters. Phys Med Biol 50(1):141-149, 2005. PMID: 15715428.
Invited Articles
- Briere TM. DVS (Dose Verification System) – Radiation detector for radiation therapy. US Oncological Disease 2007 1:78-80, 2007.
Book Chapters
- Beddar S and Briere TM. Plastic Scintillation Detectors. In: Clinical Dosimetry for Radiotherapy. Medical Physics Publishing: Madison, WI, USA, Ch 34, pg 1059 - 1082, 2009.