Tinsu Pan, Ph.D.
Department of Imaging Physics, Division of Diagnostic Imaging
About Dr. Tinsu Pan
Dr. Pan received his Ph.D. in Electrical Engineering and Computer Science from the University of Michigan, Ann Arbor, Michigan in 1991, and post-doctoral training in Nuclear Medicine at the University of Massachusetts Medical Center, Worcester, Massachusetts, from 1991 to 1993. He continued on as a research faculty on quantification of SPECT until 1996 when he joined the Applied Science Laboratory of GE Healthcare, Waukesha, Wisconsin as a senior scientist on CT. He became a faculty in the Department of Imaging Physics at the University of Texas, MD Anderson Cancer Center, Houston, Texas in 2004, is a professor in the Department of Imaging Physics and holds a joint faculty appointment in the Department of Radiation Physics at the University of Texas, MD Anderson Cancer Center.
Dr. Pan designed the cardiac CT and invented the 4D-CT on the GE LightSpeed CT during his tenure with GE. His design of 4D-CT is the most used 4D-CT in Radiation Oncology around the world. There are over 10,000 patients scanned with his 4D-CT at MD Anderson Cancer Center. He also invented average CT to help register the CT and PET images in the thorax,. The average CT has been applied in patient care at the University of Texas Medical School by Dr. K. Lance Gould for over 10,000 patients since 2006. He has also developed the world's first data-driven gated CT to mitigate the misregistration and motion artifacts on PET/CT. He has published 12 book chapters, 12 patents and over 139 peer-reviewed articles. Dr. Pan is certified by the ABR and ABSNM.
Present Title & Affiliation
Primary Appointment
Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Professor, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1991 | The University of Michigan, Ann Arbor, Michigan, US, Ph.D. in Electrical Engineering and Computer Science |
| 1985 | National Tsing-Hua University, Hsinchu, TW, M.S. in Electrical Engineering |
| 1983 | National Tsing-Hua University, Hsinchu, TW, BS in Electrical Engineering |
Postgraduate Training
| 1992-1993 | Postdoctoral Fellowship, Nuclear Medicine Physics, University of Massachusetts Medical Center, Worcester, Massachusetts |
Board Certifications
| 2007 | American Board of Radiology - Diagnostic Physics |
| 1996 | American Board of Science in Nuclear Medicine |
Experience & Service
Other Appointments/Responsibilities
Senior Scientist of CT Physics, General Electrical Medical Systems, Waukesha, WI, 1996 - 2003
ROTC, Taiwan, 1985 - 1987
Honors & Awards
| 2019 | Invention of 4D-CT, Medical Physics |
| 1990 - 1991 | Fellowship of Rackham Graduate School, The University of Michigan |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Yu B, Ozdemir S, Dong Y, Shao W, Pan T, Shi K, Gong K. Robust whole-body PET image denoising using 3D diffusion models: evaluation across various scanners, tracers, and dose levels. Eur J Nucl Med Mol Imaging, 2025. e-Pub 2025. PMID: 39912940.
- Shao HC, Mengke T, Pan T, Zhang Y. Real-time CBCT imaging and motion tracking via a single arbitrarily-angled x-ray projection by a joint dynamic reconstruction and motion estimation (DREME) framework. Phys Med Biol 70(2), 2025. e-Pub 2025. PMID: 39746309.
- Sun P, Thomas MA, Luo D, Pan T. New full-counts phase-matched data-driven gated (DDG) PET/CT. Med Phys 51(7):4646-4654, 2024. e-Pub 2024. PMID: 38648671.
- Zhao Y, Wang X, Phan J, Chen X, Lee A, Yu C, Huang K, Court LE, Pan T, Wang H, Wahid KA, Mohamed ASR, Naser M, Fuller CD, Yang J. Multi-modal segmentation with missing image data for automatic delineation of gross tumor volumes in head and neck cancers. Med Phys 51(10):7295-7307, 2024. e-Pub 2024. PMID: 38896829.
- Jang SI, Pan T, Li Y, Heidari P, Chen J, Li Q, Gong K. Spach Transformer: Spatial and Channel-Wise Transformer Based on Local and Global Self-Attentions for PET Image Denoising. IEEE Trans Med Imaging 43(6):2036-2049, 2024. e-Pub 2024. PMID: 37995174.
- Shao HC, Mengke T, Pan T, Zhang Y. Dynamic CBCT imaging using prior model-free spatiotemporal implicit neural representation (PMF-STINR). Phys Med Biol 69(11), 2024. e-Pub 2024. PMID: 38697195.
- Chen X, Zhao Y, Court LE, Wang H, Pan T, Phan J, Wang X, Ding Y, Yang J. SC-GAN: Structure-completion generative adversarial network for synthetic CT generation from MR images with truncated anatomy. Comput Med Imaging Graph 113:102353, 2024. e-Pub 2024. PMID: 38387114.
- Sun P, Thomas MA, Luo D, Pan T. Correcting CT misregistration in data-driven gated (DDG) PET with PET self-gating and deformable image registration. Med Phys 51(3):1626-1636, 2024. e-Pub 2024. PMID: 38285623.
- Gong K, Johnson K, El Fakhri G, Li Q, Pan T. PET image denoising based on denoising diffusion probabilistic model. Eur J Nucl Med Mol Imaging 51(2):358-368, 2024. e-Pub 2024. PMID: 37787849.
- Lu Y, Wilson ZJ, Xu G, Xu Z, Pan T, Wei P. Diagnostic Performance of PSMA-Based 18 F-DCFPyL PET/CT in Prostate Cancer Patients After Definitive Treatment With PSA Level <= 0.2 ng/mL. Clin Nucl Med 48(12):1021-1027, 2023. e-Pub 2023. PMID: 37801580.
- Zhao Y, Chen X, McDonald B, Yu C, Mohamed ASR, Fuller CD, Court LE, Pan T, Wang H, Wang X, Phan J, Yang J. A transformer-based hierarchical registration framework for multimodality deformable image registration. Comput Med Imaging Graph 108:102286, 2023. e-Pub 2023. PMID: 37625307.
- Zhao Y, Wang H, Yu C, Court LE, Wang X, Wang Q, Pan T, Ding Y, Phan J, Yang J. Compensation cycle consistent generative adversarial networks (Comp-GAN) for synthetic CT generation from MR scans with truncated anatomy. Med Phys 50(7):4399-4414, 2023. e-Pub 2023. PMID: 36698291.
- Zhang Y, Shao HC, Pan T, Mengke T. Dynamic cone-beam CT reconstruction using spatial and temporal implicit neural representation learning (STINR). Phys Med Biol 68(4), 2023. e-Pub 2023. PMID: 36638543.
- Koutroumpakis E, Xu T, Lopez-Mattei J, Pan T, Lu Y, Irizarry-Caro JA, Mohan R, Zhang X, Meng QH, Lin R, Xu T, Deswal A, Liao Z. Coronary artery calcium score on standard of care oncologic CT scans for the prediction of adverse cardiovascular events in patients with non-small cell lung cancer treated with concurrent chemoradiotherapy. Front Cardiovasc Med 9:1071701, 2022. e-Pub 2022. PMID: 36531700.
- Nguyen TT, Bhosale PR, Xu G, Pan T, Wei P, Lu Y. Comparison of PSMA-based 18F-DCFPyL PET/CT and pelvic multiparametric MRI for lesion detection in the pelvis in patients with prostate cancer. Am J Nucl Med Mol Imaging 12(6):166-179, 2022. e-Pub 2022. PMID: 36636233.
- Chen LW, Yang SM, Chuang CC, Wang HJ, Chen YC, Lin MW, Hsieh MS, Antonoff MB, Chang YC, Wu CC, Pan T, Chen CM. Solid Attenuation Components Attention Deep Learning Model to Predict Micropapillary and Solid Patterns in Lung Adenocarcinomas on Computed Tomography. Ann Surg Oncol 29(12):7473-7482, 2022. e-Pub 2022. PMID: 35789301.
- Lassen ML, Tzolos E, Pan T, Kwiecinski J, Cadet S, Dey D, Berman D, Slomka P. Anatomical validation of automatic respiratory motion correction for coronary 18F-sodium fluoride positron emission tomography by expert measurements from four-dimensional computed tomography. Med Phys 49(11):7085-7094, 2022. e-Pub 2022. PMID: 35766454.
- Thomas MA, Meier JG, Mawlawi OR, Sun P, Pan T. Impact of acquisition time and misregistration with CT on data-driven gated PET. Phys Med Biol 67(085012), 2022. e-Pub 2022. PMID: 35313286.
- Jimenez JE, Dai D, Xu G, Zhao R, Li T, Pan T, Wang L, Lin Y, Wang Z, Jaffray D, Hazle JD, Macapinlac HA, Wu J, Lu Y. Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma. Clin Nucl Med 47(3):209-218, 2022. e-Pub 2022. PMID: 35020640.
- Hasegawa A, Ishihara T, Pan T, Ropp AM, Winkler M, Sneider MB. Impact of pixel value truncation on image quality of low dose chest CT. Med Phys 49(5):2979-2994, 2022. e-Pub 2022. PMID: 35235216.
- Pan T, Thomas MA, Luo D. Data-driven gated (DDG) CT: An automated respiratory gating method to enable DDG PET/CT. Med Phys 49(6):3597-3611, 2022. e-Pub 2022. PMID: 35324002.
- Hasegawa A, Ishihara T, Thomas MA, Pan T. Noise reduction profile: A new method for evaluation of noise reduction techniques in CT. Med Phys 49(1):186-200, 2021. e-Pub 2021. PMID: 34837717.
- Thomas MA, Pan T. Data-driven gated PET/CT: implications for lesion segmentation and quantitation. EJNMMI Phys 8(1):64, 2021. e-Pub 2021. PMID: 34453630.
- Hasegawa A, Ishihara T, Allan Thomas M, Pan T. Technical Note: Scanner dependence of adaptive statistical iterative reconstruction with 3D noise power spectrum central frequency and noise magnitude ratios. Med Phys 48(9):4993-5003, 2021. e-Pub 2021. PMID: 34287936.
- Pan T, Lu Y, Thomas MA, Liao Z, Luo D. New data-driven gated PET/CT free of misregistration artifacts. Int J Radiat Oncol Biol Phys 109(5):1638-1646, 2021. e-Pub 2021. PMID: 33186619.
- Chen CC, Shen TY, Peterson CB, Hung GU, Pan T. Comparison of ejection fraction calculation between CT and SPECT at high heart rate: A dynamic cardiac phantom study. J Nucl Cardiol 28(1):311-316, 2021. e-Pub 2021. PMID: 31907855.
- Teyateeti A, Khan B, Teyateeti A, Chen B, Bridhikitti J, Pan T, Peng W, Macapinlac HA, Lu Y. Diagnostic performance of F-18 fluciclovine PET/CT in post-radical prostatectomy prostate cancer patients with rising prostate-specific antigen level |< 0.5 ng/mL. Nucl Med Commun 41(9):906-915, 2020. e-Pub 2020. PMID: 32796479.
- Tzolos E, Lassen ML, Pan, T, Kwiecinski J, Cadet S, Dey D, Dweck MR, Newby DE, Berman D, Slomka P. Respiration-averaged CT versus standard CT attenuation map for correction of (18)F-sodium fluoride uptake in coronary atherosclerotic lesions on hybrid PET/CT. J Nucl Cardiol 29(2):430-439, 2020. e-Pub 2020. PMID: 32617857.
- Doris MK, Otaki Y, Krishnan SK, Kwiecinski J, Rubeaux M, Alessio A, Pan T, Cadet S, Dey D, Dweck MR, Newby DE, Berman DS, Slomka PJ. Optimization of reconstruction and quantification of motion-corrected coronary PET-CT. J Nucl Cardiol 27(2):494-504, 2020. e-Pub 2020. PMID: 29948889.
- Jain, P, Zhang, S, Kanagal Shamanna, R, Ok, CY, Nomie, K, Gonzalez, GN, Gonzalez-Pagan, O, Hill, HA, Lee, HJ, Fayad, LE, Westin, JR, Nastoupil, L, Hagemeister, FB, Chen, W, Oriabure, O, Badillo, M, Jiang, C, Yao, Y, Li, S, Tang, G, Yin, CC, Patel, KP, Medeiros, LJ, Nair, R, Ahmed, S, Iyer, SP, Thirumurthi, S, Champlin, RE, Xu, G, Pan, T, Santos, DA, Wang, R, Han, G, Zhang, J, Song, X, Neelapu, SS, Romaguera, JE, Futreal, A, Flowers, CR, Fowler, N, Wang, L, Wang, L. Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL. Blood Advances 4(6):1038-1050, 2020. e-Pub 2020. PMID: 32191807.
- Pan T, Hasegawa A, Luo D, Wu CC, Vikram R. Technical Note: Impact on central frequency and noise magnitude ratios by advanced CT image reconstruction techniques. Med Phys 47(2):480-487, 2020. e-Pub 2020. PMID: 31778233.
- Gould KL, Bui L, Kitkungvan D, Pan T, Roby AE, Nguyen, TT, Johnson NP. Pitfalls in quantitative myocardial PET perfusion I: Myocardial partial volume correction. J Nucl Cardiol:386-396, 2020. e-Pub 2020.
Other Articles
- Pan, T Comments on the paper “Data-driven gating (DDG)-based motion match for improved CTAC registration. EJNMMI Physics. 2024;11(1):42.”. EJNMMI Physics 11(1), 2024. PMID: 39432164.
- Pan T, Luo D Data-driven gated positron emission tomography/computed tomography for radiotherapy. Phys Imaging Radiat Oncol 31:100601, 2024. PMID: 39040434.
- Pan T pitfalls in quantitative myocardial pet perfusion.
Selected Presentations & Talks
Local Presentations
- 2023. New Data-driven gated (DDG) PET/CT for RT. Invited. Houston, Texas, US.
- 2023. Data-driven gated PET/CT. Invited. Houston, Texas, US.
- 2023. Data-driven gated PET/CT for RT. Invited. Houston, Texas, US.
- 2022. Mitigation of mis-registration and tumor motion in PET/CT. Invited. Houston, Texas, US.
- 2014. Dynamic cardiac SPECT/PET/CT phantom. Conference. Dynamic cardiac SPECT/PET/CT phantom. Houston, TX, US.
- 2013. Initial experiences with Siemens mCT flowmotion. Conference. Initial experiences with Siemens mCT flowmotion. Houston, TX, US.
- 2013. Radiation and Pacemakers. Conference. Radiation and Pacemakers. Houston, TX, US.
- 2009. Impact of organ motion in PET SUV value. Conference. Impact of organ motion in PET SUV value. Houston, TX, US.
- 2005. 4D CBCT. Conference. 4D CBCT. Houston, TX, US.
- 2004. 4D PET/CT imaging. Conference. 4D PET/CT imaging. Houston, TX, US.
- 2004. 4D-CT application. Conference. 4D-CT application. Houston, TX, US.
- 2004. Introduction to 4D-CT. Conference. Introduction to 4D-CT. Houston, TX, US.
Regional Presentations
- 2024. New Data-driven gated PET/CT for Radiation Therapy Treatment Planning Invited Talk (Zoom). Conference. Columbia University. New York, NY, US.
- 2015. What iterative reconstruction can do to reduce patient dose and improve image quality in CT?. Conference. What iterative reconstruction can do to reduce patient dose and improve image quality in CT?. San Antonio, TX, US.
- 2015. Iterative reconstruction and system modeling: impact on administered dose, imaging time, and image quality. Conference. Iterative reconstruction and system modeling: impact on administered dose, imaging time, and image quality. San Antonio, TX, US.
- 2005. PET/CT imaging. Conference. PET/CT imaging. San Antonio, TX, US.
National Presentations
- 2023. New Data-Driven Gated (DDG) Pet/CT for Radiation Treatment Planning of NSCLC. Conference. ASTRO 2023 Annual Meeting. San Diego, CA, US.
- 2022. Mitigation of motion artifacts with DDG PET/CT. Conference. Mitigation of motion artifacts with DDG PET/CT. District of Columbia, US.
- 2022. Innovations in FDG PET/CT imaging. Conference. Innovations in FDG PET/CT imaging. District of Columbia, US.
- 2018. Mitigation of irregular respirations in 4D-CT. Conference. Mitigation of irregular respirations in 4D-CT. Nashville, TN, US.
- 2018. 4D Image Choices and Pitfalls. Conference. 4D Image Choices and Pitfalls. Las Vegas, NV, US.
- 2016. Pitfalls and Remedies in PET/CT imaging for RT planning. Conference. Pitfalls and Remedies in PET/CT imaging for RT planning. Baltimore, MD, US.
- 2015. Reducing CT radiation dose in PET/CT. Conference. Reducing CT radiation dose in PET/CT. Baltimore, MD, US.
- 2015. 4D PET/CT in Pre-meeting Categorical Seminars of Recent Advances in PET Instrumentation. Conference. 4D PET/CT in Pre-meeting Categorical Seminars of Recent Advances in PET Instrumentation. Baltimore, MD, US.
- 2015. Benefits and drawbacks of iterative image reconstructions in CT. Conference. Benefits and drawbacks of iterative image reconstructions in CT. Galveston, TX, US.
- 2015. Equipment and software choices for cardiac PET. Conference. Equipment and software choices for cardiac PET. San Antonio, TX, US.
- 2015. Iterative reconstruction to reduce patient dose and improve image quality in CT. Conference. Iterative reconstruction to reduce patient dose and improve image quality in CT. San Antonio, TX, US.
- 2014. 4D PET: Promises and Limitations. Conference. 4D PET: Promises and Limitations. Austin, TX, US.
- 2014. Do we need respiratory gating in PET/CT imaging?. Conference. Do we need respiratory gating in PET/CT imaging?. St. Louis, MO, US.
- 2010. PET/CT imaging for radiation therapy. Conference. Computer and Instrumentation Council. Salt Lake City, UT, US.
- 2010. Advances in instrumentation for PET/CT imaging of the thorax for radiation therapy. Conference. Computer and Instrumentation Council. Salt Lake City, UT, US.
- 2010. PET/CT in thoracic malignancies: Radiation treatment planning. Conference. PET Center of Excellence. Salt Lake City, UT, US.
- 2008. PET/CT for radiation therapy. Conference. PET/CT for radiation therapy. Houston, TX, US.
- 2008. Advances in CT technology on PET/CT. Conference. Advances in CT technology on PET/CT. New Orleans, LA, US.
- 2008. Effects of Advances in CT Technology on PET/CT. Conference. Effects of Advances in CT Technology on PET/CT. Newport Beach, CA, US.
- 2007. PET-CT imaging simulation of tumors in the thorax: pitfalls and workaround. Conference. PET-CT imaging simulation of tumors in the thorax: pitfalls and workaround. Minneapolis, MN, US.
- 2007. PET-CT simulation of tumors in the thorax: pitfalls and workaround. Conference. PET-CT simulation of tumors in the thorax: pitfalls and workaround. Minneapolis, MN, US.
- 2006. Incorporating CT from attenuation correction to managing motion. Conference. Incorporating CT from attenuation correction to managing motion. San Diego, CA, US.
- 2005. Instrumentation for cardiac PET/CT. Conference. Instrumentation for cardiac PET/CT. Toronto, US.
- 2005. Fundamentals of CT. Conference. Fundamentals of CT. Toronto, US.
- 2005. 4DCT: instrumentation, image acquisition, and application to radiation therapy planning. Conference. 4DCT: instrumentation, image acquisition, and application to radiation therapy planning. Orlando, FL, US.
- 2003. Advanced Cardiac Imaging. Conference. Advanced Cardiac Imaging. Taipei, US.
- 2002. Cardiovascular Imaging with Multi-slice CT. Conference. Cardiovascular Imaging with Multi-slice CT. Taipei, US.
- 2002. Cardiac CT Imaging. Conference. Cardiac CT Imaging. Boston, MA, US.
International Presentations
- 2023. New data-driven gated (DDG) PET/CT for radiation treatment planning of NSCLC. Conference. ASTRO Annual Meeting, San Diego. San Diego, US.
- 2023. Automatic trending and analysis of SPECT daily quality control data with optical character recognition AI. Conference. EANM 2023 Congress, Vienna, Austria. Vienna, AT.
- 2023. Misregistration correction of data-driven gated (DDG) PET/CT by self-gated PET and deformable image registration CT. Conference. SNMMI 2023 Annual Meeting, Chicago, US.
- 2022. New phase-matched DDG PET/CT using full counts. Conference. SNMMI 2022, Vancouver, Canada. Vancouver, CA.
- 2013. Quality Control of PET/CT Imaging. Conference. Quality Control of PET/CT Imaging, TW.
- 2013. Average CT in PET/CT for Oncology and Cardiology. Conference. Average CT in PET/CT for Oncology and Cardiology, TW.
- 2012. Quantitative PET/CT without gating, in the 3rd Cross-Strait Nuclear Medicine Joint Annual Meeting and Taiwan Nuclear Cardiology Symposium. Conference. Quantitative PET/CT without gating, in the 3rd Cross-Strait Nuclear Medicine Joint Annual Meeting and Taiwan Nuclear Cardiology Symposium, TW.
- 2009. Basic CT Physics. Conference. Basic CT Physics. Toronto, CA.
- 2009. 4D PET/CT for radiotherapy planning and cardiac imaging. Conference. 4D PET/CT for radiotherapy planning and cardiac imaging. Sanya, CN.
- 2007. PET/CT and multi-slice CT's fundamentals and applications. Conference. American Association of Physicists in Medicine. Beijing, CN.
- 2006. Cardiac CT and 4D-CT imaging. Conference. Cardiac CT and 4D-CT imaging. Linko, TW.
- 2006. Dynamic Imaging with CT and PET/CT. Conference. Dynamic Imaging with CT and PET/CT, HK.
- 2006. Dynamic Imaging with CT and PET/CT. Conference. Dynamic Imaging with CT and PET/CT. Taipei, TW.
Formal Peers
- 2017. Mitigation of irregular respiration in 4D-CT imaging. Invited. Taipei, TW.
- 2017. Cardiac PET/CT Imaging. Invited. Taoyuan, TW.
- 2016. PET ACR Accreditation. Invited. Houston, US.
- 2016. Optimization of CT radiation dose in PET/CT. Visiting, BR.
- 2015. Attenuation correction of PET data in Cardiac PET. Invited. Los Angeles, CA, US.
- 2015. Attenuation correction of the PET data with average MR. Invited. Linko, TW.
- 2015. Effect of bone in attenuation correction of the PET data in PET/MR. Invited. Linko, TW.
- 2012. Quantitative PET/CT without gating. Invited, Linko, TW.
- 2012. Feasibility of quantification of the thoracic tumor in PET/CT without 4D PET. Invited. Boston, MA, US.
- 2011. Advancements of PET/CT in Radiotherapy and Myocardial Perfusion Imaging. Invited. New Haven, CT, US.
- 2009. Dynamic imaging of CT and PET/CT for radiotherapy. Invited. Tokyo, JP.
- 2009. PET/CT for radiotherapy planning. Invited. Taichung, TW.
- 2009. New development of cine CT imaging. Invited. San Diego, CA, US.
- 2005. PET/CT imaging of the thorax. Invited. Buffalo, NY, US.
- 2002. 4DCT imaging. Invited. Boston, MA, US.
- 2002. 4DCT imaging. Invited. Boston, MA, US.
- 1996. Quantification of SPECT Imaging Workshop of SPECT Instrumentation. Visiting. Taipei, US.
- 1995. Instrumentation and Reconstruction of SPECT. Visiting. Suzhou, CN.
Grant & Contract Support
| Date: | 2026 - 2030 |
| Title: | Novel Functional Imaging Radiomic Signatures for Cardiotoxicity for Lung Cancer Patients |
| Funding Source: | NIH |
| Role: | Co-PI |
| ID: | 1R01CA299892-01 |
| Date: | 2025 - 2028 |
| Title: | Development of Deep Learning-based Anatomical Matching (DL-AM) for PET/CT Imaging of the Chest and Abdomen |
| Funding Source: | IIRA |
| Role: | Co-I |
| ID: | RP260176 |
| Date: | 2025 - 2030 |
| Title: | Stratify high-risk NSCLC patients after SBRT based on quantitative 4D-PET |
| Funding Source: | The University of Texas-Southwest |
| Role: | Co-PI |
| ID: | 1R01EB032814-01A1 |
| Date: | 2025 - 2030 |
| Title: | Stratify high-risk NSCLC patients after SBRT based on quantitative 4D-PET |
| Funding Source: | The University of Texas – Southwest |
| Role: | PI |
| ID: | R01EB032814-01 |
| Date: | 2025 - 2026 |
| Title: | Risk prediction and longitudinal assessment of cardiotoxicity and functional capacity trajectory in NSCLC patients |
| Funding Source: | NIH/NHLBI |
| Role: | Co-I |
| ID: | 5R01HL157273-02 |
| Date: | 2024 - 2029 |
| Title: | Deep Learning Methods for Improving Gallium 68-Based PET Imaging |
| Funding Source: | NIH/NCI |
| Role: | Subcontract |
| ID: | 1R01EB034692-01 |
| Date: | 2024 - 2025 |
| Title: | New data-driven gated PET/CT for radiation therapy and surgery |
| Funding Source: | MDACC IRG |
| Role: | PI |
| Date: | 2024 - 2027 |
| Title: | New data-driven gated PET/CT for Radiation Therapy |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | FP00019799 |
| Date: | 2023 - 2025 |
| Title: | Full-Counts Phase-Matched Data-Driven Gated PET/CT Imaging |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1R21CA280235-01 |
| Date: | 2023 - 2025 |
| Title: | Deep learning-based PET image reconstruction |
| Funding Source: | MASSACHUSETTS GENERAL HOSPITAL |
| Role: | PI |
| Date: | 2023 - 2024 |
| Title: | New full-counts phase-matched DDG PET/CT for Radiation Therapy |
| Funding Source: | CCSG-IDBT |
| Role: | PI |
| Date: | 2022 - 2027 |
| Title: | Early Skeletal Muscle Surveillance in Adolescent and Young Adult Cancer Patients Undergoing Chemotherapy |
| Funding Source: | NIH |
| Role: | Significant Contributor |
| Date: | 2022 - 2026 |
| Title: | Phase 1b/2 study of 177Lu girentuximab plus cabozantinib and nivolumab in treatment naive patients with advanced clear cell RCC |
| Funding Source: | DOD KCRP |
| Role: | Collaborator |
| ID: | KC210253 |
| Date: | 2022 - 2027 |
| Title: | Advanced Image Reconstruction for PET imaging of Neuroendocrine Tumors |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | FP 13928 |
| Date: | 2022 - 2027 |
| Title: | Interdisciplinary Translational Pre/Postdoctoral Program in Cancer Nanotechnology |
| Funding Source: | NIH/NCI |
| Role: | Co-Mentor |
| ID: | 5T32CA196561-08 |
| Date: | 2022 - 2024 |
| Title: | Optimization of Data Driven Gated PET/CT Imaging |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1R21CA256023-01A1 |
| Date: | 2022 - 2025 |
| Title: | A digital phenotype of skeletal muscle loss and recovery in adolescent and young adult (AYA) cancer patients during anthracycline-based therapy |
| Funding Source: | Department of Defense (DOD) |
| Role: | Co-I |
| Date: | 2021 - 2026 |
| Title: | Stratify high-risk NSCLC patients after SBRT based on quantitative 4D-PET |
| Funding Source: | The University of Texas - Southwest |
| Role: | PI |
| ID: | 1R01CA255264-01A1 |
| Date: | 2021 - 2023 |
| Title: | New Data-Driven Gated PET/CT to improve treatment planning and response assessment of lung cancer |
| Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
| Role: | PI |
| ID: | LC200125 |
| Date: | 2020 - 2022 |
| Title: | Optimization of Data Driven Gated PET/CT Imaging |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1R21CA256023-01 |
| Date: | 2020 - 2025 |
| Title: | Radiography and CT using a novel image detector system and approach for image guidance for proton therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1R01CA255177-01 |
| Date: | 2020 - 2022 |
| Title: | Optimization of PET Image Reconstruction for Lesion Detection |
| Funding Source: | Massachusetts General Hospital / NIH |
| Role: | Subcontract PI |
| ID: | 5R03EB030280-02 |
| Date: | 2020 - 2023 |
| Title: | New PET/CT Imaging for Radiotherapy Treatment Planning and Treatment Response Assessment of Lung Cancer |
| Funding Source: | ROSI Advanced Imaging Seed Grant |
| Role: | Co-PI |
| Date: | 2020 - 2022 |
| Title: | WS#30 Optimization of Data Driven Gated PET/CT for Theranostics |
| Funding Source: | GE Healthcare |
| Role: | PI |
| ID: | WS30 |
| Date: | 2020 - 2021 |
| Title: | WS#29 Establish the minimum detectable PET activity concentrations when imaging F-18 and Ga-68 labeled prostate cancer radiotracers with the Sigma PET/MR |
| Funding Source: | GE Healthcare |
| Role: | Collaborator |
| ID: | 00058508 |
| Date: | 2019 - 2020 |
| Title: | Image-guided Proton Therapy Using a Novel Monolithic Scintillator-based Radiographic and CT Imaging System |
| Funding Source: | CCSG Radiation Oncology and Cancer Imaging Program |
| Role: | PI |
| Date: | 2019 - 2021 |
| Title: | Understanding the effect of protons and photons on heart injury |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2019 - 2022 |
| Title: | Proton Therapy to Reduce Heart Damage for Lung Cancer Patients |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5R21CA222749-02 |
| Date: | 2019 - 2021 |
| Title: | Understanding the effect of protons and photons on heart injury |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1R21CA240547-01 |
| Date: | 2019 - 2022 |
| Title: | Proton radiography and CT using a novel image detection system and approach based on a monolithic scintillator and digital cameras |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1R01CA233645-01A1 |
| Date: | 2019 - 2022 |
| Title: | Proton radiography and CT using a novel image detection system and approach |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| ID: | RP190330 |
| Date: | 2018 - 2021 |
| Title: | Proton radiography and CT using a novel image detection system and approach based on a monolithic scintillator and digital cameras |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1R01CA233645-01 |
| Date: | 2017 - 2018 |
| Title: | Recruitment of established investigator |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | RR 150054 |
| Date: | 2017 - 2019 |
| Title: | Advanced micro-PET/CT/RT system for translational radiation oncology applications |
| Funding Source: | NIH/NIBIB |
| Role: | Co-I |
| ID: | 5R01EB019438-03 |
| Date: | 2016 - 2017 |
| Title: | Comparison of device-less 4DCT and conventional 4DCT in gross target volume delineation |
| Funding Source: | GE Healthcare |
| Role: | PI |
| Date: | 2015 - 2019 |
| Title: | Lung moon-shot MD Anderson Cancer Center |
| Funding Source: | MD Anderson |
| Role: | Consult |
| ID: | 710499-30-112086-21 |
| Date: | 2014 - 2015 |
| Title: | Optimization of 4D PET/CT |
| Funding Source: | MDACC/GE-CABI |
| Role: | PI |
| ID: | N/A |
| Date: | 2011 - 2015 |
| Title: | 4D Cone Beam CT for IGRT: Advanced Volumetric Imaging and Adaptive Radiotherapy for Detecting and Correcting for Inter-fractional Changes (Center Grant PI: Hak) |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Sub-Project PI |
| ID: | RP110562-P2-01 |
| Date: | 2008 - 2008 |
| Title: | Evaluation of Helical CT and Average CT in PET/CT Simulation of the Lung Cancer Patients |
| Funding Source: | GE Health Care |
| Role: | PI |
| ID: | SR2008-00024088EB |
| Date: | 2007 - 2009 |
| Title: | Phase II validation of 4-dimensional computer tomography derived ventilation image-guided radiotherapy of lung cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | CA128230-01 |
| Date: | 2006 - 2006 |
| Title: | New PET/CT techniques for improving cancer imaging |
| Funding Source: | Goodwin Fund for Technology Review Committee |
| Role: | PI |
| ID: | No assigned # |
| Date: | 2006 - 2007 |
| Title: | 4D PET/CT Imaging of the lung and esophageal tumors in the lower thorax |
| Funding Source: | GE Health Care |
| Role: | PI |
| ID: | CS2006-0017041SS |
| Date: | 2005 - 2010 |
| Title: | 4D Cone Beam CT |
| Funding Source: | Varian Medical Systems |
| Role: | PI |
| ID: | CS2005-00012856SP |
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CV information above last modified May 29, 2025