Top

Tinsu Pan, Ph.D.

Department of Imaging Physics, Division of Diagnostic Imaging

About Dr. Tinsu Pan

Dr. Pan received his Ph.D. in Electrical Engineering and Computer Science from the University of Michigan, Ann Arbor, Michigan in 1991, and post-doctoral training in Nuclear Medicine at the University of Massachusetts Medical Center, Worcester, Massachusetts, from 1991 to 1993. He continued on as a research faculty on quantification of SPECT until 1996 when he joined the Applied Science Laboratory of GE Healthcare, Waukesha, Wisconsin as a senior scientist on CT. He became a faculty in the Department of Imaging Physics at the University of Texas, MD Anderson Cancer Center, Houston, Texas in 2004, is a professor in the Department of Imaging Physics and holds a joint faculty appointment in the Department of Radiation Physics at the University of Texas, MD Anderson Cancer Center.

Dr. Pan designed the cardiac CT and invented the 4D-CT on the GE LightSpeed CT during his tenure with GE. His design of 4D-CT is the most used 4D-CT in Radiation Oncology around the world. There are over 10,000 patients scanned with his 4D-CT at MD Anderson Cancer Center. He also invented average CT to help register the CT and PET images in the thorax,. The average CT has been applied in patient care at the University of Texas Medical School by Dr. K. Lance Gould for over 10,000 patients since 2006. He has also developed the world's first data-driven gated CT to mitigate the misregistration and motion artifacts on PET/CT. He has published 12 book chapters, 12 patents and over 139 peer-reviewed articles. Dr. Pan is certified by the ABR and ABSNM.

Primary Appointment

Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX

Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1991	The University of Michigan, Ann Arbor, Michigan, US, Ph.D. in Electrical Engineering and Computer Science
1985	National Tsing-Hua University, Hsinchu, TW, M.S. in Electrical Engineering
1983	National Tsing-Hua University, Hsinchu, TW, BS in Electrical Engineering

Postgraduate Training

1992-1993

Postdoctoral Fellowship, Nuclear Medicine Physics, University of Massachusetts Medical Center, Worcester, Massachusetts

Board Certifications

2007	American Board of Radiology - Diagnostic Physics
1996	American Board of Science in Nuclear Medicine

Experience & Service

Academic Appointments

Associate Professor, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2003 - 2010

Associate Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2003 - 2010

Assistant Professor, Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA, 1995 - 1996

Instructor, Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA, 1993 - 1995

Post-doc, Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA, 1992 - 1993

Research Assistant, Department of Internal Medicine, University of Michigan Hospital, The University of Michigan, Ann Arbor, MI, 1988 - 1991

Research Assistant, Department of Environmental Health Sciences, The University of Michigan, Ann Arbor, MI, 1987 - 1991

Other Appointments/Responsibilities

Senior Scientist of CT Physics, General Electrical Medical Systems, Waukesha, WI, 1996 - 2003

ROTC, Taiwan, 1985 - 1987

Honors & Awards

2019	Invention of 4D-CT, Medical Physics
1990 - 1991	Fellowship of Rackham Graduate School, The University of Michigan

Professional Memberships

Radiological Society of North America

2017 - 2019

American Association of Physicists in Medicine

2012 - 2017

American Society for Therapeutic Radiology and Oncology

2008 - Present

Society of Nuclear Medicine

2004 - Present

American Association of Physicists in Medicine

1992 - Present

Selected Publications

Peer-Reviewed Articles

Yu B, Ozdemir S, Dong Y, Shao W, Pan T, Shi K, Gong K. Robust whole-body PET image denoising using 3D diffusion models: evaluation across various scanners, tracers, and dose levels. Eur J Nucl Med Mol Imaging 52(7):2549-2562, 2025. e-Pub 2025. PMID: 39912940.
Shao HC, Mengke T, Pan T, Zhang Y. Real-time CBCT imaging and motion tracking via a single arbitrarily-angled x-ray projection by a joint dynamic reconstruction and motion estimation (DREME) framework. Phys Med Biol 70(2), 2025. e-Pub 2025. PMID: 39746309.
Pan T, Luo D. Data-driven gated positron emission tomography/computed tomography for radiotherapy. Phys Imaging Radiat Oncol 31:100601, 2024. e-Pub 2024. PMID: 39040434.
Sun P, Thomas MA, Luo D, Pan T. New full-counts phase-matched data-driven gated (DDG) PET/CT. Med Phys 51(7):4646-4654, 2024. e-Pub 2024. PMID: 38648671.
Zhao Y, Wang X, Phan J, Chen X, Lee A, Yu C, Huang K, Court LE, Pan T, Wang H, Wahid KA, Mohamed ASR, Naser M, Fuller CD, Yang J. Multi-modal segmentation with missing image data for automatic delineation of gross tumor volumes in head and neck cancers. Med Phys 51(10):7295-7307, 2024. e-Pub 2024. PMID: 38896829.
Jang SI, Pan T, Li Y, Heidari P, Chen J, Li Q, Gong K. Spach Transformer: Spatial and Channel-Wise Transformer Based on Local and Global Self-Attentions for PET Image Denoising. IEEE Trans Med Imaging 43(6):2036-2049, 2024. e-Pub 2024. PMID: 37995174.
Shao HC, Mengke T, Pan T, Zhang Y. Dynamic CBCT imaging using prior model-free spatiotemporal implicit neural representation (PMF-STINR). Phys Med Biol 69(11), 2024. e-Pub 2024. PMID: 38697195.
Chen X, Zhao Y, Court LE, Wang H, Pan T, Phan J, Wang X, Ding Y, Yang J. SC-GAN: Structure-completion generative adversarial network for synthetic CT generation from MR images with truncated anatomy. Comput Med Imaging Graph 113:102353, 2024. e-Pub 2024. PMID: 38387114.
Sun P, Thomas MA, Luo D, Pan T. Correcting CT misregistration in data-driven gated (DDG) PET with PET self-gating and deformable image registration. Med Phys 51(3):1626-1636, 2024. e-Pub 2024. PMID: 38285623.
Gong K, Johnson K, El Fakhri G, Li Q, Pan T. PET image denoising based on denoising diffusion probabilistic model. Eur J Nucl Med Mol Imaging 51(2):358-368, 2024. e-Pub 2024. PMID: 37787849.
Lu Y, Wilson ZJ, Xu G, Xu Z, Pan T, Wei P. Diagnostic Performance of PSMA-Based 18 F-DCFPyL PET/CT in Prostate Cancer Patients After Definitive Treatment With PSA Level <= 0.2 ng/mL. Clin Nucl Med 48(12):1021-1027, 2023. e-Pub 2023. PMID: 37801580.
Zhao Y, Chen X, McDonald B, Yu C, Mohamed ASR, Fuller CD, Court LE, Pan T, Wang H, Wang X, Phan J, Yang J. A transformer-based hierarchical registration framework for multimodality deformable image registration. Comput Med Imaging Graph 108:102286, 2023. e-Pub 2023. PMID: 37625307.
Zhao Y, Wang H, Yu C, Court LE, Wang X, Wang Q, Pan T, Ding Y, Phan J, Yang J. Compensation cycle consistent generative adversarial networks (Comp-GAN) for synthetic CT generation from MR scans with truncated anatomy. Med Phys 50(7):4399-4414, 2023. e-Pub 2023. PMID: 36698291.
Zhang Y, Shao HC, Pan T, Mengke T. Dynamic cone-beam CT reconstruction using spatial and temporal implicit neural representation learning (STINR). Phys Med Biol 68(4), 2023. e-Pub 2023. PMID: 36638543.
Nguyen TT, Bhosale PR, Xu G, Pan T, Wei P, Lu Y. Comparison of PSMA-based 18F-DCFPyL PET/CT and pelvic multiparametric MRI for lesion detection in the pelvis in patients with prostate cancer. Am J Nucl Med Mol Imaging 12(6):166-179, 2022. e-Pub 2022. PMID: 36636233.
Koutroumpakis E, Xu T, Lopez-Mattei J, Pan T, Lu Y, Irizarry-Caro JA, Mohan R, Zhang X, Meng QH, Lin R, Xu T, Deswal A, Liao Z. Coronary artery calcium score on standard of care oncologic CT scans for the prediction of adverse cardiovascular events in patients with non-small cell lung cancer treated with concurrent chemoradiotherapy. Front Cardiovasc Med 9:1071701, 2022. e-Pub 2022. PMID: 36531700.
Chen LW, Yang SM, Chuang CC, Wang HJ, Chen YC, Lin MW, Hsieh MS, Antonoff MB, Chang YC, Wu CC, Pan T, Chen CM. Solid Attenuation Components Attention Deep Learning Model to Predict Micropapillary and Solid Patterns in Lung Adenocarcinomas on Computed Tomography. Ann Surg Oncol 29(12):7473-7482, 2022. e-Pub 2022. PMID: 35789301.
Lassen ML, Tzolos E, Pan T, Kwiecinski J, Cadet S, Dey D, Berman D, Slomka P. Anatomical validation of automatic respiratory motion correction for coronary 18F-sodium fluoride positron emission tomography by expert measurements from four-dimensional computed tomography. Med Phys 49(11):7085-7094, 2022. e-Pub 2022. PMID: 35766454.
Thomas MA, Meier JG, Mawlawi OR, Sun P, Pan T. Impact of acquisition time and misregistration with CT on data-driven gated PET. Phys Med Biol 67(085012), 2022. e-Pub 2022. PMID: 35313286.
Hasegawa A, Ishihara T, Pan T, Ropp AM, Winkler M, Sneider MB. Impact of pixel value truncation on image quality of low dose chest CT. Med Phys 49(5):2979-2994, 2022. e-Pub 2022. PMID: 35235216.
Jimenez JE, Dai D, Xu G, Zhao R, Li T, Pan T, Wang L, Lin Y, Wang Z, Jaffray D, Hazle JD, Macapinlac HA, Wu J, Lu Y. Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma. Clin Nucl Med 47(3):209-218, 2022. e-Pub 2022. PMID: 35020640.
Pan T, Thomas MA, Luo D. Data-driven gated (DDG) CT: An automated respiratory gating method to enable DDG PET/CT. Med Phys 49(6):3597-3611, 2022. e-Pub 2022. PMID: 35324002.
Hasegawa A, Ishihara T, Thomas MA, Pan T. Noise reduction profile: A new method for evaluation of noise reduction techniques in CT. Med Phys 49(1):186-200, 2021. e-Pub 2021. PMID: 34837717.
Thomas MA, Pan T. Data-driven gated PET/CT: implications for lesion segmentation and quantitation. EJNMMI Phys 8(1):64, 2021. e-Pub 2021. PMID: 34453630.
Hasegawa A, Ishihara T, Allan Thomas M, Pan T. Technical Note: Scanner dependence of adaptive statistical iterative reconstruction with 3D noise power spectrum central frequency and noise magnitude ratios. Med Phys 48(9):4993-5003, 2021. e-Pub 2021. PMID: 34287936.
Pan T, Lu Y, Thomas MA, Liao Z, Luo D. New data-driven gated PET/CT free of misregistration artifacts. Int J Radiat Oncol Biol Phys 109(5):1638-1646, 2021. e-Pub 2021. PMID: 33186619.
Chen CC, Shen TY, Peterson CB, Hung GU, Pan T. Comparison of ejection fraction calculation between CT and SPECT at high heart rate: A dynamic cardiac phantom study. J Nucl Cardiol 28(1):311-316, 2021. e-Pub 2021. PMID: 31907855.
Teyateeti A, Khan B, Teyateeti A, Chen B, Bridhikitti J, Pan T, Peng W, Macapinlac HA, Lu Y. Diagnostic performance of F-18 fluciclovine PET/CT in post-radical prostatectomy prostate cancer patients with rising prostate-specific antigen level |< 0.5 ng/mL. Nucl Med Commun 41(9):906-915, 2020. e-Pub 2020. PMID: 32796479.
Tzolos E, Lassen ML, Pan, T, Kwiecinski J, Cadet S, Dey D, Dweck MR, Newby DE, Berman D, Slomka P. Respiration-averaged CT versus standard CT attenuation map for correction of (18)F-sodium fluoride uptake in coronary atherosclerotic lesions on hybrid PET/CT. J Nucl Cardiol 29(2):430-439, 2020. e-Pub 2020. PMID: 32617857.
Doris MK, Otaki Y, Krishnan SK, Kwiecinski J, Rubeaux M, Alessio A, Pan T, Cadet S, Dey D, Dweck MR, Newby DE, Berman DS, Slomka PJ. Optimization of reconstruction and quantification of motion-corrected coronary PET-CT. J Nucl Cardiol 27(2):494-504, 2020. e-Pub 2020. PMID: 29948889.
Jain, P, Zhang, S, Kanagal Shamanna, R, Ok, CY, Nomie, K, Gonzalez, GN, Gonzalez-Pagan, O, Hill, HA, Lee, HJ, Fayad, LE, Westin, JR, Nastoupil, L, Hagemeister, FB, Chen, W, Oriabure, O, Badillo, M, Jiang, C, Yao, Y, Li, S, Tang, G, Yin, CC, Patel, KP, Medeiros, LJ, Nair, R, Ahmed, S, Iyer, SP, Thirumurthi, S, Champlin, RE, Xu, G, Pan, T, Santos, DA, Wang, R, Han, G, Zhang, J, Song, X, Neelapu, SS, Romaguera, JE, Futreal, A, Flowers, CR, Fowler, N, Wang, L, Wang, L. Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL. Blood Advances 4(6):1038-1050, 2020. e-Pub 2020. PMID: 32191807.
Gould KL, Bui L, Kitkungvan D, Pan T, Roby AE, Nguyen, TT, Johnson NP. Pitfalls in quantitative myocardial PET perfusion I: Myocardial partial volume correction. J Nucl Cardiol:386-396, 2020. e-Pub 2020.
Pan T, Hasegawa A, Luo D, Wu CC, Vikram R. Technical Note: Impact on central frequency and noise magnitude ratios by advanced CT image reconstruction techniques. Med Phys 47(2):480-487, 2020. e-Pub 2020. PMID: 31778233.
Olivia PD, Ng CS, Zhou S, Kappadath CS, Pan T, Kyle JA. Comparison of enhancement quantification from virtual unenhanced images to true unenhanced images in multiphase renal Dual-Energy computed tomography: A phantom study. J Appl Clin Med Phys 20(8):171-179, 2019. e-Pub 2019. PMID: 31423728.
Pan EY, Luo D, Pan T. Potential effects of low-dose average CT on cardiac implantable electronic devices. J Nucl Cardiol 26(4):1161-1165, 2019. e-Pub 2019. PMID: 29344923.
Darne, C, Alsanea, FM, Robertson, D, Guan, F, Pan, T, Grosshans, DR, Beddar, S. A proton imaging system using a volumetric liquid scintillator. Biomedical Physics and Engineering Express 5(4), 2019. e-Pub 2019. PMID: 32194988.
Pan T, Einstein SA, Kappadath SC, Grogg KS, Lois Gomez C, Alessio AM, Hunter WC, El Fakhri G, Kinahan PE, Mawlawi OR. Performance evaluation of the 5-Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2-2012 Standard. Med Phys 46(7):3025-3033, 2019. e-Pub 2019. PMID: 31069816.
Dai D, Chuang HH, Macapinlac HA, Li T, Pan T. Correlation of fluorine 18-labeled sodium fluoride uptake and arterial calcification on whole-body PET/CT in cancer patients. Nucl Med Commun 40(6):604-610, 2019. e-Pub 2019. PMID: 30688757.
Fayad H, Gilles M, Pan T, Visvikis D. A 4D global respiratory motion model of the thorax based on CT images: A proof of concept. Med Phys, 2018. e-Pub 2018. PMID: 29772057.
Kesner A, Laforest R, Otazo R, Jennifer K, Pan T. Medical imaging data in the digital innovation age. Med Phys 45(4):e40-e52, 2018. e-Pub 2018. PMID: 29405298.
Yue J, Shi Q, Xu T, Jeter M, Chen TY, Komaki R, Gomez DR, Pan T, Cleeland CS, Liao Z, Wang XS. Patient-reported lung symptoms as an early signal of impending radiation pneumonitis in patients with non-small cell lung cancer treated with chemoradiation: an observational study. Qual Life Res 27(6):1563-1570, 2018. e-Pub 2018. PMID: 29549533.
Martin R, Ahmad M, Hugo G, Pan T. Iterative volume of interest based 4D cone-beam CT. Med Phys 44(12):6515-6528, 2017. e-Pub 2017. PMID: 28898423.
Martin R, Pan T. Target volume and artifact evaluation of a new data-driven 4D CT. Pract Radiat Oncol 7(5):e345-e354, 2017. e-Pub 2017. PMID: 28341317.
Pan T, Martin RM, Luo D. New prospective 4D-CT for mitigating the effects of irregular respiratory motion. Phys Med Biol 62(15):N350-N361, 2017. e-Pub 2017. PMID: 28715346.
Chism CB, Ravizzini GC, Macapinlac HA, Pan T. Quantitative comparison between regularized time-of-flight and OSEM PET reconstructions for small 18F-FDG-avid lesions. Nucl Med Commun 38(6):529-536, 2017. e-Pub 2017. PMID: 28383318.
Yue J, McKeever M, Sio TT, Xu T, Huo J, Shi Q, Nguyen QN, Komaki R, Gomez DR, Pan T, Wang XS, Liao Z. Association of lung fluorodeoxyglucose uptake with radiation pneumonitis after concurrent chemoradiation for non-small cell lung cancer. Clin Transl Radiat Oncol 4:1-7, 2017. e-Pub 2017. PMID: 29594201.
Zhou R, Liao Z, Pan T, Milgrom SA, Pinnix CC, Shi A, Tang L, Yang J, Liu Y, Gomez D, Nguyen QN, Dabaja BS, Court L, Yang J. Cardiac atlas development and validation for automatic segmentation of cardiac substructures. Radiother Oncol 122(1):66-71, 2017. e-Pub 2017. PMID: 27939201.
Slomka PJ, Rubeaux M, Le Meunier L, Dey D, Lazewatsky JL, Pan T, Dweck MR, Newby DE, Germano G, Berman DS. Dual-gated motion-frozen cardiac PET with Flurpiridaz F-18. J Nucl Med 56(12):1876-81, 2015. e-Pub 2015. PMID: 26405171.
Ai H, Pan T. Feasibility of using respiration-averaged MR images for attenuation correction of cardiac PET/MR imaging. J Appl Clin Med Phys 16(4):311-321, 2015. e-Pub 2015. PMID: 26218995.
Hui C, Suh Y, Robertson D, Pan T, Das P, Crane CH, Beddar S. Internal respiratory surrogate in multislice 4D CT using a combination of Fourier transform and anatomical features. Med Phys 42(7):4338-48, 2015. e-Pub 2015. PMID: 26133631.
Zhang Y, Yin FF, Pan T, Vergalasova I, Ren L. Preliminary clinical evaluation of a 4D-CBCT estimation technique using prior information and limited-angle projections. Radiother Oncol 115(1):22-9, 2015. e-Pub 2015. PMID: 25818396.
Castillo SJ, Castillo R, Castillo E, Pan T, Ibbott G, Balter P, Hobbs B, Guerrero T. Evaluation of 4D CT acquisition methods designed to reduce artifacts. J Appl Clin Med Phys 16(2):23-32, 2015. e-Pub 2015. PMID: 26103169.
Dang J, Gu X, Pan T, Wang J. A pilot evaluation of a 4D CBCT scheme based on simultaneous motion estimation and image reconstruction. Int J Radiat Oncol Biol Phys 91(2):410-8, 2015. e-Pub 2015. PMID: 25636763.
Martin R, Rubinstein A, Ahmad M, Court L, Pan T. Evaluation of intrinsic respiratory signal determination methods for 4D CBCT adapted for mice. Med Phys 42(1):154, 2015. e-Pub 2015. PMID: 25563256.
Yan H, Zhen X, Folkerts M, Li Y, Pan T, Cervino L, Jiang SB, Jia X. A hybrid reconstruction algorithm for fast and accurate 4D cone-beam CT imaging. Med Phys 41(7):071903, 2014. e-Pub 2014. PMID: 24989381.
Fave X, Yang J, Carvalho L, Martin R, Pan T Balter P, Court L. Upright cone beam CT imaging using the onboard imager. Med Phys 41(6):061906, 2014. e-Pub 2014. PMID: 24877817.
Oki Y, Chuang H, Chasen B, Jessop A, Pan T, Fanale M, Dabaja B, Fowler N, Romaguera J, Fayad L, Hagemeister F, Rodriguez MA, Neelapu S, Samaniego F, Kwak L, Younes A. The prognostic value of interim positron emission tomography scan in patients with classical Hodgkin lymphoma. Br J Haematol 165(1):112-6, 2014. e-Pub 2014. PMID: 24386943.
Mathieu KB, Ai H, Fox PS, Godoy MC, Munden RF, de Groot PM, Pan T. Radiation dose reduction for CT lung cancer screening using ASIR and MBIR: a phantom study. J Appl Clin Med Phys 15(2):4515, 2014. e-Pub 2014. PMID: 24710436.
Palmer J, Yang J, Pan T, Court LE. Motion of the esophagus due to cardiac motion. PLoS One 9(2):e89126, 2014. e-Pub 2014. PMID: 24586540.
Riegel AC, Bucci MK, Mawlawi OR, Ahmad M, Luo D, Chandler A, Pan T. Defining internal target volume using positron emission tomography for radiation therapy planning of moving lung tumors. J Appl Clin Med Phys 15(1):4600, 2014. e-Pub 2014. PMID: 24423860.
Yen TC, Visvikis D, Pan T, Fang YH. Biomedical imaging: role and opportunities of medical imaging in the "omics" era. Biomed Res Int 2014:930213, 2014. e-Pub 2014. PMID: 24995335.
Castillo SJ, Castillo R, Balter P, Pan T, Ibbott G, Hobbs B, Yuan Y, Guerrero T. Assessment of a quantitative metric for 4D CT artifact evaluation by observer consensus. J Appl Clin Med Phys 15(3):4718, 2014. e-Pub 2014. PMID: 24892346.
Busse N, Erwin W, Pan T. Evaluation of a semiautomated lung mass calculation technique for internal dosimetry applications. Med Phys 40(12):122503, 2013. e-Pub 2013. PMID: 24320539.
Pan T, Riegel AC, Ahmad MU, Sun X, Chang JY, Luo D. New weighted maximum-intensity-projection images from cine CT for delineation of the lung tumor plus motion. Med Phys 40(6/061901):061901, 2013. e-Pub 2013. PMID: 23718592.
Ahmad M, Pan T. Target-specific optimization of four-dimensional cone beam computed tomography. Med Phys 39(9):5683-5696, 2012. e-Pub 2012. PMID: 22957634.
Zhang X, Liu H, Balter P, Allen PK, Komaki R, Pan T, Chuang HH, Chang JY. Positron emission tomography for assessing local failure after stereotactic body radiotherapy for non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 83(5):1558-1565, 2012. e-Pub 2012. PMID: 22572078.
Fayad H, Pan T, Pradier O, Visvikis D. Patient specific respiratory motion modeling using a 3D patient's external surface. Med Phys 39(6):3386-3395, 2012. e-Pub 2012. PMID: 22755719.
Chang G, Chang T, Pan T, Clark JW, Mawlawi OR. Determination of internal target volume from a single positron emission tomography/computed tomography scan in lung cancer. Int J Radiat Oncol Biol Phys 82(2):708-714, 2012. e-Pub 2012. PMID: 22197228.
Wang X, Pan T, Pinnix C, Zhang SX, Salehpour M, Sun TL, Gladish G, Strom EA, Perkins GH, Tereffe W, Woodward W, Hoffman KE, Buchholz TA, Yu TK. Cardiac motion during deep-inspiration breath-hold: implications for breast cancer radiotherapy. Int J Radiat Oncol Biol Phys 82(2):708-14, 2012. e-Pub 2012. PMID: 21444161.
Ahmad M, Balter P, Pan T. Four-dimensional volume-of-interest reconstruction for cone-beam computed tomography-guided radiation therapy. Med Phys 38(10):5646-56, 2011. e-Pub 2011. PMID: 21992381.
Tian Z, Jia X, Yuan K, Pan T, Jiang SB. Low-dose CT reconstruction via edge-preserving total variation regularization. Phys Med Biol 56(18):5949-67, 2011. e-Pub 2011. PMID: 21860076.
Fayad H, Pan T, Clement JF, Visvikis D. Correlation of respiratory motion between external patient surface and internal anatomical landmarks. Med Phys 38(6):3157-64, 2011. e-Pub 2011. PMID: 21815390.
Jackson J, Pan T, Tonkopi E, Swanston N, Macapinlac HA, Rohren EM. Implementation of automated tube current modulation in PET/CT: prospective selection of a noise index and retrospective patient analysis to ensure image quality. J Nucl Med Technol 39(2):83-90, 2011. e-Pub 2011. PMID: 21565950.
Perin EC, Tian M, Marini FC, Silva GV, Zheng Y, Baimbridge F, Quan X, Fernandes MR, Gahremanpour A, Young D, Paolillo V, Mukhopadhyay U, Borne AT, Uthamanthil R, Brammer D, Jackson J, Decker WK, Najjar AM, Thomas MW, Volgin A, Rabinovich B, Soghomonyan S, Jeong HJ, Rios JM, Steiner D, Robinson S, Mawlawi O, Pan T, Stafford J, Kundra V, Li C, Alauddin MM, Willerson JT, Shpall E, Gelovani JG. Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. PLoS One 6(9):e22949, 2011. e-Pub 2011. PMID: 21912635.
Chang G, Chang T, Pan T, Clark JW, Mawlawi OR. Joint correction of respiratory motion artifact and partial volume effect in lung/thoracic PET/CT imaging. Med Phys 37(12):6221-32, 2010. e-Pub 2010. PMID: 21302779.
Zamora DA, Riegel AC, Sun X, Balter P, Starkschall G, Mawlawi O, Pan T. Thoracic target volume delineation using various maximum-intensity-projection computed tomography image sets for radiotherapy treatment planning. Med Phys 37(11):5811-20, 2010. e-Pub 2010. PMID: 21158293.
Johnson NP, Pan T, Gould KL. Shifted helical computed tomography to optimize cardiac positron emission tomography-computed tomography coregistration: quantitative improvement and limitations. Mol Imaging 9(5):256-67, 2010. e-Pub 2010. PMID: 20868626.
Riegel AC, Bucci MK, Mawlawi OR, Johnson V, Ahmad M, Sun X, Luo D, Chandler AG, Pan T. Target definition of moving lung tumors in positron emission tomography: correlation of optimal activity concentration thresholds with object size, motion extent, and source-to-background ratio. Med Phys 37(4):1742-1752, 2010. e-Pub 2010. PMID: 20443495.
Maurer J, Pan T, Yin FF. Slow gantry rotation acquisition technique for on-board four-dimensional digital tomosynthesis. Med Phys 37(2):921-33, 2010. e-Pub 2010. PMID: 20229901.
Chang G, Chang T, Pan T, Clark JW, Mawlawi OR. Implementation of an automated respiratory amplitude gating technique for PET/CT: clinical evaluation. J Nucl Med 51(1):16-24, 2010. e-Pub 2010. PMID: 20008993.
Tonkopi E, Chi PC, Mawlawi O, Riegel AC, Rohren EM, Macapinlac HA, Pan T. Average CT in PET studies of colorectal cancer paients with metastasis in the liver and esophageal cancer patients. J Appl Clin Med Phys 11(1):217-228, 2010. e-Pub 2010.
Bergner F, Berkus T, Oelhafen M, Kunz P, Pan T, Grimmer R, Ritschl L, Kachelriess M. An investigation of 4D cone-beam CT algorithms for slowly rotating scanners. Med Phys 37(9):5044-53, 2010. e-Pub 2010.
Bergner F, Berkus T, Oelhafen M, Kunz P, Pan T, Kachelriess M. Autoadaptive phase-correlated (AAPC) reconstruction for 4D CBCT. Med Phys 36(12):5695-706, 2009. e-Pub 2009. PMID: 20095282.
Chang G, Pan T, Qiao F, Clark JW, Mawlawi OR. Comparison between two super-resolution implementations in PET imaging. Med Phys 36(4):1370-1383, 2009. e-Pub 2009. PMID: 19472644.
Riegel AC, Chang JY, Vedam SS, Johnson V, Chi PC, Pan T. Cine computed tomography without respiratory surrogate in planning stereotactic radiotherapy for non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 73(2):433-41, 2009. e-Pub 2009. PMID: 18644683.
Dey J, Pan T. Semi-automatic segmentation of non-contrast-enhanced 4D-CT cardiac datasets with application to respiratory motion estimation. IEEE Trans Nuc Si 56(6):3662-3671, 2009. e-Pub 2009.
Riegel AC, Ahmad M, Sun X, Pan T. Dose calculation with respiration-averaged CT processed from cine CT without a respiratory surrogate. Med Phys 35(12):5738-5747, 2008. e-Pub 2008. PMID: 19175131.
Chang G, Pan T, Clark JW, Mawlawi OR. Optimization of super-resolution processing using incomplete image sets in PET imaging. Med Phys 35(12):5748-5757, 2008. e-Pub 2008. PMID: 19175132.
Pan T, Chen L, Orton CG. Point/counterpoint. PET/CT will become standard practice for radiotherapy simulation and planning. Med Phys 35(9):3825-7, 2008. e-Pub 2008. PMID: 18841832.
Chi PC, Mawlawi O, Luo D, Liao Z, Macapinlac HA, Pan T. Effects of respiration-averaged computed tomography on positron emission tomography/computed tomography quantification and its potential impact on gross tumor volume delineation. Int J Radiat Oncol Biol Phys 71(3):890-9, 2008. e-Pub 2008. PMID: 18514781.
Beddar AS, Briere TM, Balter P, Pan T, Tolani N, Ng C, Szklaruk J, Krishnan S. 4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning. Radiother Oncol 87(3):445-8, 2008. e-Pub 2008. PMID: 18194819.
Gould KL, Pan T, Loghin C, Johnson NP, Sdringola S. Reducing radiation dose in rest-stress cardiac PET/CT by single poststress cine CT for attenuation correction: quantitative validation. J Nucl Med 49(5):738-45, 2008. e-Pub 2008. PMID: 18413384.
Mawlawi O, Kappadath SC, Pan T, Rohren E, Macapinlac HA. Factors affecting quantification in PET/CT imaging. Current Medical Imaging Reviews 4(1):34-45, 2008. e-Pub 2008.
Chi PM, Mawlawi O, Luo D, Liao Z, Macapinlac H, Pan T. Effect of respiration-averaged CT on PET/CT quantification and its potential impact on ross tumor volume delineation. Int J Radiat Oncol Biol Phys 71:890-899, 2008. e-Pub 2008.
Qiao F, Pan T, Clark JW, Mawlawi O. Joint model of motion and anatomy for PET image reconstruction. Med Phys 34(12):4626-39, 2007. e-Pub 2007. PMID: 18196790.
Pan T, Sun X, Luo D. Improvement of the cine-CT based 4D-CT imaging. Med Phys 34(11):4499-503, 2007. e-Pub 2007. PMID: 18072515.
Bruzzi JF, Munden RF, Truong MT, Marom EM, Sabloff BS, Gladish GW, Iyer RB, Pan T, Macapinlac HA, Erasmus JJ. PET/CT of esophageal cancer: its role in clinical management. Radiographics 27(6):1635-52, 2007. e-Pub 2007. PMID: 18025508.
Britton KR, Starkschall G, Tucker SL, Pan T, Nelson C, Chang JY, Cox JD, Mohan R, Komaki R. Assessment of gross tumor volume regression and motion changes during radiotherapy for non-small-cell lung cancer as measured by four-dimensional computed tomography. Int J Radiat Oncol Biol Phys 68(4):1036-46, 2007. e-Pub 2007. PMID: 17379442.
Liu HH, Balter P, Tutt T, Choi B, Zhang J, Wang C, Chi M, Luo D, Pan T, Hunjan S, Starkschall G, Rosen I, Prado K, Liao Z, Chang J, Komaki R, Cox JD, Mohan R, Dong L. Assessing respiration-induced tumor motion and internal target volume using four-dimensional computed tomography for radiotherapy of lung cancer. Int J Radiat Oncol Biol Phys 68(2):531-40, 2007. e-Pub 2007. PMID: 17398035.
Lu J, Guerrero TM, Munro P, Jeung A, Chi PC, Balter P, Zhu XR, Mohan R, Pan T. Four-dimensional cone beam CT with adaptive gantry rotation and adaptive data sampling. Med Phys 34(9)(9):3520-3529, 2007. e-Pub 2007. PMID: 17926955.
Gould KL, Pan T, Loghin C, Johnson N, Guha A, Sdringola S. Frequent diagnostic errors in cardiac PET-CT due to misregistration of CT attentuation and emission PET images: a definite analyis of causes, consequences and corrections. J Nuc Med (*Cover Illustration) 48:1112-1121, 2007. e-Pub 2007.
Starkschall G, Desai N, Balter P, Prado K, Luo D, Cody D, Pan T. Quantitative assessment of four-dimensional computed tomography image acquisition quality. J Appl Clin Med Phys 8(3)(3):1-20, 2007. e-Pub 2007. PMID: 17712299.
Abdelnour AF, Nehmeh SA, Pan T, Humm JL, Vernon P, Schoder H, Rosenzweig KE, Mageras GS, Yorke E, Larson SM, Erdi YE. Phase and amplitude binning for 4D-CT imaging. Phys Med Biol 52:3515-3529, 2007. e-Pub 2007.
Chi PM, Mawlawi O, Nehmeh SA, Erdi YE, Balter PA, Pan T. Design of respiration averaged CT for attenuation correction of the PET data from PET/CT. Med Phys (*Cover Illustration, 34(6):2039-2047, 2007. e-Pub 2007.
Gould KL, Pan T. Reply:attenuation correction for stress and rest PET 82Rb myocardial perfusion images. J Nuc Med 48:1913-1914, 2007. e-Pub 2007.
Beddar A, Kainz K, Briere TM, Tsunashima Y, Pan T, Prado K, Mohan R, Gillin M, Krishnan S. Correlation between internal fiducial tumor motion and external marker motion for liver tumors imaged with 4D-CT. Int J Radiat Oncol Biol Phys 67(2):630-638, 2007. e-Pub 2007.
Liu H, Balter P, Tutt T, Bum C, Zhang J, Wang C, Chi P, Luo D, Pan T, Hunjan S. Assessing respiration-induced tumor motion and internal target volume using 4DCT for radition therapy of lung cancer. Int J Radiat Oncol Biol Phys 68:531-540, 2007. e-Pub 2007.
Guerrero T, Johnson V, Hart J, Pan T, Khan M, Luo D, Liao Z, Ajani J Komaki R. Radiation Pneumonitis: Local dose versus [18F]-fluorodeoxyglucose uptake response in irradiated lung. Int J Rdiat Oncol Biol Phys 68:1030-1035, 2007. e-Pub 2007.
Qioa F, Pan T, Clark JW, Mawlawi O. Region of interest motion compensation for PET image reconstruction. Phys Med Biol 52:2675-2689, 2007. e-Pub 2007.
Pan T, Mawlawi O, Luo D, Liu HH, Chi PC, Mar MV, Gladish G, Truong M, Erasmus J, Jr, Liao Z, Macapinlac HA. Attenuation correction of PET cardiac data with low-dose average CT in PET/CT. Med. Phys 33:3931-3938, 2006. e-Pub 2006. PMID: 17089855.
Mawlawi O, Pan TS, Macapinlac HA. PET/CT imaging techniques, considerations, and artifacts. J Thorac Imaging 21(2):99-110, 2006. e-Pub 2006. PMID: 16770227.
Mawlawi O, Erasmus JJ, Munden RF, Pan T, Knight AE, Macapinlac HA, Podoloff DA, Chasen M. Quantifying the effect of IV contrast media on integrated PET/CT: clinical evaluation. AJR Am J Roentgenol 186(2):308-19, 2006. e-Pub 2006. PMID: 16423932.
Guerrero T, Sanders K, Castillo E, Zhang Y, Bidaut L, Pan T, Komaki R. Dynamic ventilation imaging from four-dimensional computed tomography. Phys Med Biol 51:777-91, 2006. e-Pub 2006. PMID: 16467578.
Mawlawi O, Erasmus JJ, Pan T, Cody DD, Campbell R, Lonn AH, Kohlmyer S, Macapinlac HA, Podoloff DA. Truncation artifact on PET/CT: impact on measurements of activity concentration and assessment of a correction algorithm. AJR Am J Roentgenol 186:1458-1467, 2006. e-Pub 2006. PMID: 16632745.
Chi PC, Balter P, Luo D, Mohan R, Pan T. Relation of external surface to internal tumor motion studied with cine CT. Med Phys 33:3116-3123, 2006. e-Pub 2006. PMID: 17022203.
Truong MT, Pan T, Erasmus JJ. Pitfalls in integrated CT-PET of the thorax: implications in oncologic imaging. J Thorac Imaging 21:111-22, 2006. e-Pub 2006. PMID: 16770228.
Mawlawi O, Erasmus JJ, Munden RF, Pan T, Knight AE, Macapinlac HA, Podoloff, DA, Chasen M. Quantifying the effect of intravenous contrast media on integrated PET/CT imaging clinical evaluation. AJR 186:308-319, 2006. e-Pub 2006.
Qiao F, Pan T, Clark JW, Mawlawi O. A motion-incorporated reconstruction method for gated PET studies. Phys Med Biol 51:3769-3783, 2006. e-Pub 2006.
Rietzel E, Pan T, Chen GTY. Four-dimensional computed tomography: imaging formation and clinical protocol. Med. Phys 32(4):874-889, 2005. e-Pub 2005.
Pan T. Comparison of helical and cine acquisitions for 4D-CT imaging with multislice CT. Med. Phys 32(2):627-634, 2005. e-Pub 2005.
Pan T, Mawlawi O, Nehmeh SA, Erdi YE, Luo D, Liu HH, Castillo R, Mohan R, Liao Z, Macapinlac HA. Attenuation correction of PET images with respiration-averaged CT images in PET/CT. J Nuc Med 46(9):1481-1487, 2005. e-Pub 2005.
Pan T, Lee TY, Rietzel E, Chen GTY. 4D-CT imaging of a volume influenced by respiratory motion on multi-slice CT. Med. Phys 31(2):333-340, 2004. e-Pub 2004.
Nehmeh SA, Erdi YE, Pan T, Pevsner A, Rosenzweig KE, York E, Mageras GS, Schoder H, Vernon P, Squire O, Mostafavi H, Larson SM, Humm JL. Four-dimensional (4D) PET/CT imaging of the thorax. Med. Phys 31(12):3179-3186, 2004. e-Pub 2004.
Erdi YE, Nehmeh SA, Pan T, Pevsner A, Rosenzweig KE, Mageras GS, York E, Schoder H, Hsiao W, Squire OD, Vernon P, Ashman JB, Mostafavi H, Larson SM, Humm JL. The CT motion quantitation of lung lesions and its impact on PET-measured SUVs. J. Nuc. Med 45(8):1287-1292, 2004. e-Pub 2004.
Nehmeh SA, Erdi YE, Pan T, York E, Mageras GS, Rosenzweig KE, Schoder H, Mostafavi H, Squire O, Pevsner A, Larson SM, Humm JL. Quantitation of respiratory motion during 4D-PET/CT acquisition. Med. Phys 31(6):1333-1338, 2004. e-Pub 2004.
Nehmeh SA, Erdi YE, Kalaigian H, Kolbert KS, Pan T, Yeung H, Squire O, Sinha A, Larson SM, Humm JL. Correction for oral contrast artifacts in the CT attenuation corrected PET images of the Discovery LS PET/CT. J. Nuc. Med 44(12):1940-1944, 2003. e-Pub 2003.
Pretorius PH, PanT, Narayanan MV, King MA. A study of the influence of local variations in myocardial thickness on SPECT perfusion imaging. IEEE Trans. Nuc. Sci 49:2304-2308, 2002. e-Pub 2002.
Hu H, Pan T, Shen Y. Multi-slice helical CT: image temporal resolution. IEEE Trans. Med. Imag 19(384-390), 2000. e-Pub 2000.
Toth TL, Bromberg NB, Pan T, Rabe J, Woloschek SJ, Li J, Seidenschnur GE. A dose reduction X-ray beam positioning system for high-speed multislice CT scanners. Med. Phys 27(12):2659-2668, 2000. e-Pub 2000.
Cline H, Coulam C, Yavuz M, Rubin GD, Edic P, Pan T, Shen Y, Avila R, Turek M, Iatrou M, Loree A, Ishaque Nand Senzig R. Coronary artery angiography using multislice computed tomography images. Circulation 102:1589-1590, 2000. e-Pub 2000.
Licho R, Glick SJ, Xia W, Pan T, Penney BC, King MA. Attenuation compensation in Tc-99m SPECT brain imaging: a comparison of the use of attenuation maps derived from transmission versus emission data. J. Nuc. Med 40(3):456-463, 1999. e-Pub 1999.
Kohli V, King MA, Glick SJ, Pan TS. Comparison of frequency-distance relationship and gaussian-diffusion-based methods of compensation for distance-dependent spatial resolution in SPECT imaging. Phys Med Biol 43(4):1025-1037, 1998. e-Pub 1998. PMID: 9572525.
Pretorius PH, King MA, Pan TS, de Vries DJ, Glick SJ, Byrne CL. Reducing the influence of the partial volume effect on SPECT activity quantitation with 3D modelling of spatial resolution in iterative reconstruction. Phys Med Biol 43(2):407-420, 1998. e-Pub 1998. PMID: 9509535.
Pan TS, Luo DS, Kohli V, King MA. Influence of osem, elliptical orbits and background activity on SPECT 3D resolution recovery. Phys Med Biol 42(12):2517-2529, 1997. e-Pub 1997. PMID: 9434304.
Pretorius PH, Xia W, King MA, Tsui BM, Pan T, Villegas BJ. Evaluation of right and left ventricular volume and ejection fraction using a mathematical cardiac torso phantom. J Nucl Med 38(10):1528-1535, 1997. e-Pub 1997. PMID: 9379187.
Luo D, King MA, Morgan HT, Pan T, Xia W, Pretorius PH, Case JA. Investigations into possible causes of hot inferior wall artifacts in attenuation corrected cardiac perfusion images. IEEE Trans. Nuc. Sci 44(3):1146-1153, 1997. e-Pub 1997.
King MA, Pan T, Luo D. An investigation of aliasing with gaussian-diffusion modeling of SPECT system spatial resolution. IEEE Trans. Nuc. Sci 44(3):1375-1380, 1997. e-Pub 1997.
Pretorius PH, King MA, Pan T, Hutton BF. Attenuation correction strategies for multi-energy photon emitters using SPECT. IEEE Trans. Nuc. Sci 44(3):1323-1328, 1997. e-Pub 1997.
Pan T, Tsui BMW, Byrne CL. Choice of initial conditions in the ML reconstruction for transmission CT with truncated projection data. IEEE Trans. Med. Imaging 16(4):426-438, 1997. e-Pub 1997.
King MA, deVries DJ, Pan T, Pretorius PH, Case JA. An investigation of the filtering of TEW scatter estimates used to compensate for scatter with ordered subset reconstruction. IEEE Trans. Nuc. Sci 44(3):1140-1145, 1997. e-Pub 1997.
Xia W, Glick SJ, Pan T, Soares EJ, Luo D. Region of interest evaluation of SPECT image reconstruction methods using a realistic brain phantom. IEEE Trans. Nuc. Sci 44(3):1336-1341, 1997. e-Pub 1997.
Yu DC, Chang W, Pan T. A study of reconstruction accuracy for a cardiac SPECT system with multi-segmental collimation. IEEE Trans. Nuc. Sci 44(3):1403-1408, 1997. e-Pub 1997.
Pan T, King MA, DLuo Dahlberg ST, Villegas BJ. Estimation of attenuation maps from scatter and photopeak window SPECT images of Tc-99m labeled Sestamibi. J. Nucl. Card 4(1):42-51, 1997. e-Pub 1997.
Glick SJ, King MA, Pan T, Soares EJ. Compensation for non-uniform attenuation in SPECT brain imaging. IEEE Trans. Nuc. Sci 43:737-750, 1996. e-Pub 1996.
King MA, Tsui BMW, Pan T, Glick SJ, Soares EJ. Attenuation compensation for cardiac SPECT imaging: part 2. attenuation compensation algorithms. J. Nucl. Card 3:55-63, 1996. e-Pub 1996.
Pan T, King MA, de Vries DJ, Ljungberg M. Segmentation of the body and lungs from Compton scatter and photopeak window data in SPECT: a Monte Carlo investigation. IEEE Trans. Med. Imag 15(1):13-24, 1996. e-Pub 1996.
King MA, Xia W, de Vries DJ, Pan T, Villegas B, Tsui BMW, Ljungberg MH, Morgan HT. A Monte Carlo investigation of artifacts caused by liver uptake in SPECT perfusion imaging with Tc-99m labeled agents. J. Nucl. Card 3:18-29, 1996. e-Pub 1996.
Case JA, Pan T, King MA, Luo D, Penney BC. Reduction of truncation artifacts in fan-beam transmission imaging using a spatially varying Gamma prior. IEEE Trans. Nuc. Sci 42:2260-2265, 1995. e-Pub 1995.
Pan T, King MA, Penney BC, Rajeevan N, Luo D, Case JA. Reduction of truncation artifacts in fan beam transmission by using Compton scatter data. IEEE Trans. Nuc. Sci 42:1310-1320, 1995. e-Pub 1995.
King MA, Tsui BMW, Pan T. Attenuation compensation for cardiac SPECT imaging: part 1. impact of attenuation, and methods of estimating attenuation maps. J. Nucl. Card 2:513-524, 1995. e-Pub 1995.
Glick SJ, King MA, Pan T, Soares EJ. An analytic approach for compensation of non-uniform attenuation in cardiac SPECT imaging. Phys. Med. Biol 10:1677-1693, 1995. e-Pub 1995.
Zellers ET, Pan T, Patrash S, Han M, Batterman SA. Extended disjoint principal-components regression analysis of SAW vapor sensor array responses. Sensors and Actuators B 12:123-133, 1993. e-Pub 1993.
Clinthorne NH, PanT, P-C C, Rogers WL, Stamos JA. Preconditioning methods for improved convergence rates in iterative reconstructions. IEEE Trans. Med. Imaging 12:78-83, 1993. e-Pub 1993.
Pan T, Yagle AE, Clinthorne NH, Rogers WL. Acceleration and filtering of the generalized Landweber iteration using a variable shaping matrix. IEEE Trans. Med. Imaging 12:278-286, 1993. e-Pub 1993.
Pan T, Yagle AE. Acceleration of Landweber-type algorithms by suppression of projection on the maximum singular vector. IEEE Trans. Med. Imaging 11:479-487, 1992. e-Pub 1992.
Pan T, Yagle AE. Numerical study of multigrid implementations of some iterative image reconstruction algorithms. IEEE Trans. Med. Imaging 10(4):572-588, 1991. e-Pub 1991.

Invited Articles

Kesner A, Pan T, Zaidi H. Data-driven motion correction will replace motion-tracking devices in molecular imaging-guided radiation therapy treatment planning. Med Phys, 2018. e-Pub 2018. PMID: 29679489.
Slomka PJ, Pan T, Germano G. Imaging moving heart structures with PET. J Nucl Cardiol 23(3):486-90, 2016. e-Pub 2016. PMID: 25809083.
Slomka PJ, Pan T, Germano G. Recent Advances and Future Progress in PET Instrumentation. Semin Nucl Med 46(1):5-19, 2016. e-Pub 2016. PMID: 26687853.
Slomka PJ, Pan T, Berman DS, Germano G. Advances in SPECT and PET hardware. Prog Cardiovasc Dis 57(6):566-78, 2015. e-Pub 2015. PMID: 25721706.
Pan T, Zaidi H. Attenuation correction strategies for PET/CT and 4D PET/CT. PET Clinics 8:37-50, 2013. e-Pub 2013.
Zaidi H, Pan T. Recent advances in hybrid imaging for radiation therapy planning: the cutting edge. PET Clinics 6(2):207-226, 2011. e-Pub 2011.
Pan T, Mawlawi O. PET/CT in radiation oncology. Med Phys 35(11):4955-4966, 2008. e-Pub 2008. PMID: 19070229.

Editorials

Pan T. Respiratory gating in PET/CT: A step in the right direction. J Nucl Cardiol 25(2):416-418, 2018. PMID: 27580615.

Book Chapters

Pan T. CT in hybrid SPECT/CT and PET/CT. In: Basic Sciences of Nuclear Medicine. Springer, 2021.
Low D, Pan T, Wen N, Glide-Hurst CK. Imaging simulation for lung cancer IGRT. In: Principles and Practice of Image-Guided Radiation Therapy of Lung Cancer. Taylor & Francis, 21-42, 2017.
Cai J, Low D, Pan T, Liu Y, Chang Z, Lu W. Advances in imaging simulation for lung cancer IGRT. In: Principles and Practice of Image-Guided Radiation Therapy of Lung Cancer. Taylor & Francis, 263-292, 2017.
Pan T. Motion artifacts and correction techniques in PET/CT. In: Basic Science of PET Imaging. Springer International Publishing, 379-396, 2016.
Pan T. Four-Dimensional Cone-Beam Computed Tomography. In: Cone Beam Computed Tomography. CRC Press, 2014.
Pan T. Four-Dimensional Computed Tomography. In: Technology and Applications (Devices, Circuits, and Systems). CRC Press, 2013.
Pan T. Helical 4D-CT and comparison with cine 4D-CT. In: 4D Modeling and Estimation of Respiratory Motion for Radiation Therapy. Springer, 25-41, 2013.
King MA, Pan T, Pretorius PH. Attenuation/Scatter/Resolution Correction: Physics Aspects. In: Clinical Nuclear Cardiology: State of the Art and Future Directions. 4th. Elsevier, 2010.
Flohr T, Pan T. Image Reconstruction for ECG-Triggered and ECG-Gated Multislice CT. In: CT of the Heart: Principles and Applications. Humana Press, 2004.
King MA, Tsui BMW, Pan T. Attenuation and Scatter Correction for SPECT. In: Nuclear Cardiology: State of the Art and Future Directions. Mosby, 1999.
Glick SJ, King MA, Pan T, and Soares EJ. An Analytical Approach of Compensation for Non-Uniform Attenuation and 3D Detector Response in Cardiac SPECT Imaging. In: Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine. Kluwer Academic Publishers, 1996.
Pan T, King MA. Estimation of the lung regions from Compton scatter data in SPECT. In: Monte Carlo Methods in Nuclear Medicine. Institute of Physics Publishing, 1988.

Patents

Phase-driven multi-sector reconstruction for multi-slice helical CT. Patent Number: US6,504,894.
Calibration simplification for a computed tomograph system. Patent Number: US6,325,539.
Correction algorithm for bone-induced spectral artifacts in computed tomography imaging. Patent Number: US6,115,487.
System, program product, and methods for attenuation correction of emission data on PET/CT and SPEC/CT. Patent Number: US 7,787,675.
Half-scan algorithm for use with a high-speed multi-row fan beam helical detector. Patent Number: US6,301,325.
Local CT image reconstruction with limited x-ray exposure. Patent Number: US6,246,742.
Methods and apparatus for cardiac imaging with conventional computed tomography. Patent Number: US6,639,965.
Method and apparatus for acquiring and analyzing cardiac data from a patient. Patent Number: US6,628,743.
High pitch cardiac helical scan with extended reconstruction windows. Patent Number: US6,865,250.
Hybrid reconstruction for high pitch multi-slice helical cardiac imaging. Patent Number: US6,597,803.
System and method of imaging using a variable speed for thorax imaging. Patent Number: US 7,848,790.
Cardiac helical half scan reconstructions for multiple detector row CT. Patent Number: US6,628,742.
Method and apparatus of cardiac CT imaging using ECG and mechanical motion signals. Patent Number: US6,721,386.
Methods and apparatus for efficient data acquisition in CT scanners. Patent Number: US6,272,201.

Less

Selected Presentations & Talks

Local Presentations

2023. New Data-driven gated (DDG) PET/CT for RT. Invited. Houston, Texas, US.
2023. Data-driven gated PET/CT. Invited. Houston, Texas, US.
2023. Data-driven gated PET/CT for RT. Invited. Houston, Texas, US.
2022. Mitigation of mis-registration and tumor motion in PET/CT. Invited. Houston, Texas, US.
2014. Dynamic cardiac SPECT/PET/CT phantom. Conference. Dynamic cardiac SPECT/PET/CT phantom. Houston, TX, US.
2013. Initial experiences with Siemens mCT flowmotion. Conference. Initial experiences with Siemens mCT flowmotion. Houston, TX, US.
2013. Radiation and Pacemakers. Conference. Radiation and Pacemakers. Houston, TX, US.
2009. Impact of organ motion in PET SUV value. Conference. Impact of organ motion in PET SUV value. Houston, TX, US.
2005. 4D CBCT. Conference. 4D CBCT. Houston, TX, US.
2004. 4D PET/CT imaging. Conference. 4D PET/CT imaging. Houston, TX, US.
2004. 4D-CT application. Conference. 4D-CT application. Houston, TX, US.
2004. Introduction to 4D-CT. Conference. Introduction to 4D-CT. Houston, TX, US.

Regional Presentations

2024. New Data-driven gated PET/CT for Radiation Therapy Treatment Planning Invited Talk (Zoom). Conference. Columbia University. New York, NY, US.
2015. What iterative reconstruction can do to reduce patient dose and improve image quality in CT?. Conference. What iterative reconstruction can do to reduce patient dose and improve image quality in CT?. San Antonio, TX, US.
2015. Iterative reconstruction and system modeling: impact on administered dose, imaging time, and image quality. Conference. Iterative reconstruction and system modeling: impact on administered dose, imaging time, and image quality. San Antonio, TX, US.
2005. PET/CT imaging. Conference. PET/CT imaging. San Antonio, TX, US.

National Presentations

2023. New Data-Driven Gated (DDG) Pet/CT for Radiation Treatment Planning of NSCLC. Conference. ASTRO 2023 Annual Meeting. San Diego, CA, US.
2022. Mitigation of motion artifacts with DDG PET/CT. Conference. Mitigation of motion artifacts with DDG PET/CT. District of Columbia, US.
2022. Innovations in FDG PET/CT imaging. Conference. Innovations in FDG PET/CT imaging. District of Columbia, US.
2018. Mitigation of irregular respirations in 4D-CT. Conference. Mitigation of irregular respirations in 4D-CT. Nashville, TN, US.
2018. 4D Image Choices and Pitfalls. Conference. 4D Image Choices and Pitfalls. Las Vegas, NV, US.
2016. Pitfalls and Remedies in PET/CT imaging for RT planning. Conference. Pitfalls and Remedies in PET/CT imaging for RT planning. Baltimore, MD, US.
2015. Reducing CT radiation dose in PET/CT. Conference. Reducing CT radiation dose in PET/CT. Baltimore, MD, US.
2015. 4D PET/CT in Pre-meeting Categorical Seminars of Recent Advances in PET Instrumentation. Conference. 4D PET/CT in Pre-meeting Categorical Seminars of Recent Advances in PET Instrumentation. Baltimore, MD, US.
2015. Benefits and drawbacks of iterative image reconstructions in CT. Conference. Benefits and drawbacks of iterative image reconstructions in CT. Galveston, TX, US.
2015. Equipment and software choices for cardiac PET. Conference. Equipment and software choices for cardiac PET. San Antonio, TX, US.
2015. Iterative reconstruction to reduce patient dose and improve image quality in CT. Conference. Iterative reconstruction to reduce patient dose and improve image quality in CT. San Antonio, TX, US.
2014. 4D PET: Promises and Limitations. Conference. 4D PET: Promises and Limitations. Austin, TX, US.
2014. Do we need respiratory gating in PET/CT imaging?. Conference. Do we need respiratory gating in PET/CT imaging?. St. Louis, MO, US.
2010. PET/CT imaging for radiation therapy. Conference. Computer and Instrumentation Council. Salt Lake City, UT, US.
2010. Advances in instrumentation for PET/CT imaging of the thorax for radiation therapy. Conference. Computer and Instrumentation Council. Salt Lake City, UT, US.
2010. PET/CT in thoracic malignancies: Radiation treatment planning. Conference. PET Center of Excellence. Salt Lake City, UT, US.
2008. PET/CT for radiation therapy. Conference. PET/CT for radiation therapy. Houston, TX, US.
2008. Advances in CT technology on PET/CT. Conference. Advances in CT technology on PET/CT. New Orleans, LA, US.
2008. Effects of Advances in CT Technology on PET/CT. Conference. Effects of Advances in CT Technology on PET/CT. Newport Beach, CA, US.
2007. PET-CT imaging simulation of tumors in the thorax: pitfalls and workaround. Conference. PET-CT imaging simulation of tumors in the thorax: pitfalls and workaround. Minneapolis, MN, US.
2007. PET-CT simulation of tumors in the thorax: pitfalls and workaround. Conference. PET-CT simulation of tumors in the thorax: pitfalls and workaround. Minneapolis, MN, US.
2006. Incorporating CT from attenuation correction to managing motion. Conference. Incorporating CT from attenuation correction to managing motion. San Diego, CA, US.
2005. Instrumentation for cardiac PET/CT. Conference. Instrumentation for cardiac PET/CT. Toronto, US.
2005. Fundamentals of CT. Conference. Fundamentals of CT. Toronto, US.
2005. 4DCT: instrumentation, image acquisition, and application to radiation therapy planning. Conference. 4DCT: instrumentation, image acquisition, and application to radiation therapy planning. Orlando, FL, US.
2003. Advanced Cardiac Imaging. Conference. Advanced Cardiac Imaging. Taipei, US.
2002. Cardiovascular Imaging with Multi-slice CT. Conference. Cardiovascular Imaging with Multi-slice CT. Taipei, US.
2002. Cardiac CT Imaging. Conference. Cardiac CT Imaging. Boston, MA, US.

International Presentations

2023. New data-driven gated (DDG) PET/CT for radiation treatment planning of NSCLC. Conference. ASTRO Annual Meeting, San Diego. San Diego, US.
2023. Automatic trending and analysis of SPECT daily quality control data with optical character recognition AI. Conference. EANM 2023 Congress, Vienna, Austria. Vienna, AT.
2023. Misregistration correction of data-driven gated (DDG) PET/CT by self-gated PET and deformable image registration CT. Conference. SNMMI 2023 Annual Meeting, Chicago, US.
2022. New phase-matched DDG PET/CT using full counts. Conference. SNMMI 2022, Vancouver, Canada. Vancouver, CA.
2013. Quality Control of PET/CT Imaging. Conference. Quality Control of PET/CT Imaging, TW.
2013. Average CT in PET/CT for Oncology and Cardiology. Conference. Average CT in PET/CT for Oncology and Cardiology, TW.
2012. Quantitative PET/CT without gating, in the 3rd Cross-Strait Nuclear Medicine Joint Annual Meeting and Taiwan Nuclear Cardiology Symposium. Conference. Quantitative PET/CT without gating, in the 3rd Cross-Strait Nuclear Medicine Joint Annual Meeting and Taiwan Nuclear Cardiology Symposium, TW.
2009. Basic CT Physics. Conference. Basic CT Physics. Toronto, CA.
2009. 4D PET/CT for radiotherapy planning and cardiac imaging. Conference. 4D PET/CT for radiotherapy planning and cardiac imaging. Sanya, CN.
2007. PET/CT and multi-slice CT's fundamentals and applications. Conference. American Association of Physicists in Medicine. Beijing, CN.
2006. Cardiac CT and 4D-CT imaging. Conference. Cardiac CT and 4D-CT imaging. Linko, TW.
2006. Dynamic Imaging with CT and PET/CT. Conference. Dynamic Imaging with CT and PET/CT, HK.
2006. Dynamic Imaging with CT and PET/CT. Conference. Dynamic Imaging with CT and PET/CT. Taipei, TW.

Formal Peers

2017. Mitigation of irregular respiration in 4D-CT imaging. Invited. Taipei, TW.
2017. Cardiac PET/CT Imaging. Invited. Taoyuan, TW.
2016. PET ACR Accreditation. Invited. Houston, US.
2016. Optimization of CT radiation dose in PET/CT. Visiting, BR.
2015. Attenuation correction of PET data in Cardiac PET. Invited. Los Angeles, CA, US.
2015. Attenuation correction of the PET data with average MR. Invited. Linko, TW.
2015. Effect of bone in attenuation correction of the PET data in PET/MR. Invited. Linko, TW.
2012. Quantitative PET/CT without gating. Invited, Linko, TW.
2012. Feasibility of quantification of the thoracic tumor in PET/CT without 4D PET. Invited. Boston, MA, US.
2011. Advancements of PET/CT in Radiotherapy and Myocardial Perfusion Imaging. Invited. New Haven, CT, US.
2009. Dynamic imaging of CT and PET/CT for radiotherapy. Invited. Tokyo, JP.
2009. PET/CT for radiotherapy planning. Invited. Taichung, TW.
2009. New development of cine CT imaging. Invited. San Diego, CA, US.
2005. PET/CT imaging of the thorax. Invited. Buffalo, NY, US.
2002. 4DCT imaging. Invited. Boston, MA, US.
2002. 4DCT imaging. Invited. Boston, MA, US.
1996. Quantification of SPECT Imaging Workshop of SPECT Instrumentation. Visiting. Taipei, US.
1995. Instrumentation and Reconstruction of SPECT. Visiting. Suzhou, CN.

Less

Grant & Contract Support

Date:	2026 - 2031
Title:	Improving Clinical Workflow in Nuclear Cardiology Using Deep Learning Technology
Funding Source:	NIH
Role:	PI

Date:	2026 - 2030
Title:	Novel Functional Imaging Radiomic Signatures for Cardiotoxicity for Lung Cancer Patients
Funding Source:	NIH/NCI
Role:	Co-PI
ID:	1R01CA299892-01A1

Date:	2025 - 2028
Title:	Development of Deep Learning-based Anatomical Matching (DL-AM) for PET/CT Imaging of the Chest and Abdomen
Funding Source:	Cancer Prevention Research Institute of Texas (CPRIT)
Role:	Co-I
ID:	RP260176

Date:	2025 - 2030
Title:	Stratify high-risk NSCLC patients after SBRT based on quantitative 4D-PET
Funding Source:	The University of Texas-Southwest
Role:	Co-PI
ID:	1R01EB032814-01A1

Date:	2025 - 2030
Title:	Stratify high-risk NSCLC patients after SBRT based on quantitative 4D-PET
Funding Source:	The University of Texas – Southwest
Role:	PI
ID:	R01EB032814-01

Date:	2025 - 2025
Title:	New full-counts phase-matched DDG PET/CT for Radiation Therapy
Funding Source:	CCSG-IDBT
Role:	PI

Date:	2024 - 2028
Title:	Deep Learning Methods for Improving Gallium 68-Based PET Imaging
Funding Source:	NIH/NIBIB
Role:	Subcontract
ID:	1R01EB034692-01

Date:	2024 - 2026
Title:	New data-driven gated PET/CT for radiation therapy and surgery
Funding Source:	MDACC Shark Tank IDBT Award
Role:	PI

Date:	2024 - 2027
Title:	New data-driven gated PET/CT for Radiation Therapy
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	PI
ID:	FP00019799

Date:	2023 - 2025
Title:	Full-Counts Phase-Matched Data-Driven Gated PET/CT Imaging
Funding Source:	NIH/NCI
Role:	PI
ID:	1R21CA280235-01

Date:	2023 - 2025
Title:	Deep learning-based PET image reconstruction
Funding Source:	MASSACHUSETTS GENERAL HOSPITAL
Role:	PI

Date:	2022 - 2027
Title:	Early Skeletal Muscle Surveillance in Adolescent and Young Adult Cancer Patients Undergoing Chemotherapy
Funding Source:	NIH
Role:	Significant Contributor

Date:	2022 - 2026
Title:	Phase 1b/2 study of 177Lu girentuximab plus cabozantinib and nivolumab in treatment naive patients with advanced clear cell RCC
Funding Source:	DOD KCRP
Role:	Collaborator
ID:	KC210253

Date:	2022 - 2027
Title:	Advanced Image Reconstruction for PET imaging of Neuroendocrine Tumors
Funding Source:	NIH/NCI
Role:	PI
ID:	FP 13928

Date:	2022 - 2027
Title:	Interdisciplinary Translational Pre/Postdoctoral Program in Cancer Nanotechnology
Funding Source:	NIH/NCI
Role:	Co-Mentor
ID:	5T32CA196561-08

Date:	2022 - 2024
Title:	Optimization of Data Driven Gated PET/CT Imaging
Funding Source:	NIH/NCI
Role:	PI
ID:	1R21CA256023-01A1

Date:	2022 - 2025
Title:	A digital phenotype of skeletal muscle loss and recovery in adolescent and young adult (AYA) cancer patients during anthracycline-based therapy
Funding Source:	Department of Defense (DOD)
Role:	Co-I

Date:	2021 - 2026
Title:	Stratify high-risk NSCLC patients after SBRT based on quantitative 4D-PET
Funding Source:	The University of Texas - Southwest
Role:	PI
ID:	1R01CA255264-01A1

Date:	2021 - 2026
Title:	Risk prediction and longitudinal assessment of cardiotoxicity and functional capacity trajectory in NSCLC patients
Funding Source:	NIH/NHLBI
Role:	Co-I
ID:	5R01HL157273-04

Date:	2021 - 2023
Title:	New Data-Driven Gated PET/CT to improve treatment planning and response assessment of lung cancer
Funding Source:	DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP)
Role:	PI
ID:	LC200125

Date:	2020 - 2022
Title:	Optimization of Data Driven Gated PET/CT Imaging
Funding Source:	NIH/NCI
Role:	PI
ID:	1R21CA256023-01

Date:	2020 - 2025
Title:	Radiography and CT using a novel image detector system and approach for image guidance for proton therapy
Funding Source:	NIH/NCI
Role:	Co-I
ID:	1R01CA255177-01

Date:	2020 - 2022
Title:	Optimization of PET Image Reconstruction for Lesion Detection
Funding Source:	Massachusetts General Hospital / NIH
Role:	Subcontract PI
ID:	5R03EB030280-02

Date:	2020 - 2023
Title:	New PET/CT Imaging for Radiotherapy Treatment Planning and Treatment Response Assessment of Lung Cancer
Funding Source:	ROSI Advanced Imaging Seed Grant
Role:	Co-PI

Date:	2020 - 2021
Title:	WS#29 Establish the minimum detectable PET activity concentrations when imaging F-18 and Ga-68 labeled prostate cancer radiotracers with the Sigma PET/MR
Funding Source:	GE Healthcare
Role:	Collaborator
ID:	00058508

Date:	2020 - 2022
Title:	WS#30 Optimization of Data Driven Gated PET/CT for Theranostics
Funding Source:	GE Healthcare
Role:	PI
ID:	WS30

Date:	2019 - 2020
Title:	Image-guided Proton Therapy Using a Novel Monolithic Scintillator-based Radiographic and CT Imaging System
Funding Source:	CCSG Radiation Oncology and Cancer Imaging Program
Role:	PI

Date:	2019 - 2021
Title:	Understanding the effect of protons and photons on heart injury
Funding Source:	NIH/NCI
Role:	Co-I

Date:	2019 - 2022
Title:	Proton Therapy to Reduce Heart Damage for Lung Cancer Patients
Funding Source:	NIH/NCI
Role:	Co-I
ID:	5R21CA222749-02

Date:	2019 - 2021
Title:	Understanding the effect of protons and photons on heart injury
Funding Source:	NIH/NCI
Role:	Co-I
ID:	1R21CA240547-01

Date:	2019 - 2022
Title:	Proton radiography and CT using a novel image detection system and approach based on a monolithic scintillator and digital cameras
Funding Source:	NIH/NCI
Role:	Co-I
ID:	1R01CA233645-01A1

Date:	2019 - 2022
Title:	Proton radiography and CT using a novel image detection system and approach
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Co-I
ID:	RP190330

Date:	2018 - 2021
Title:	Proton radiography and CT using a novel image detection system and approach based on a monolithic scintillator and digital cameras
Funding Source:	NIH/NCI
Role:	Co-I
ID:	1R01CA233645-01

Date:	2017 - 2018
Title:	Recruitment of established investigator
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Collaborator
ID:	RR 150054

Date:	2017 - 2019
Title:	Advanced micro-PET/CT/RT system for translational radiation oncology applications
Funding Source:	NIH/NIBIB
Role:	Co-I
ID:	5R01EB019438-03

Date:	2016 - 2017
Title:	Comparison of device-less 4DCT and conventional 4DCT in gross target volume delineation
Funding Source:	GE Healthcare
Role:	PI

Date:	2015 - 2019
Title:	Lung moon-shot MD Anderson Cancer Center
Funding Source:	MD Anderson
Role:	Consult
ID:	710499-30-112086-21

Date:	2014 - 2015
Title:	Optimization of 4D PET/CT
Funding Source:	MDACC/GE-CABI
Role:	PI
ID:	N/A

Date:	2011 - 2015
Title:	4D Cone Beam CT for IGRT: Advanced Volumetric Imaging and Adaptive Radiotherapy for Detecting and Correcting for Inter-fractional Changes (Center Grant PI: Hak)
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Sub-Project PI
ID:	RP110562-P2-01

Date:	2008 - 2008
Title:	Evaluation of Helical CT and Average CT in PET/CT Simulation of the Lung Cancer Patients
Funding Source:	GE Health Care
Role:	PI
ID:	SR2008-00024088EB

Date:	2007 - 2009
Title:	Phase II validation of 4-dimensional computer tomography derived ventilation image-guided radiotherapy of lung cancer
Funding Source:	NIH/NCI
Role:	Co-I
ID:	CA128230-01

Date:	2006 - 2006
Title:	New PET/CT techniques for improving cancer imaging
Funding Source:	Goodwin Fund for Technology Review Committee
Role:	PI
ID:	No assigned #

Date:	2006 - 2007
Title:	4D PET/CT Imaging of the lung and esophageal tumors in the lower thorax
Funding Source:	GE Health Care
Role:	PI
ID:	CS2006-0017041SS

Date:	2005 - 2010
Title:	4D Cone Beam CT
Funding Source:	Varian Medical Systems
Role:	PI
ID:	CS2005-00012856SP

CV information above last modified June 23, 2025

Tinsu Pan, Ph.D.

About Dr. Tinsu Pan

Present Title & Affiliation

Primary Appointment

Education & Training

Degree-Granting Education

Postgraduate Training

Board Certifications

Experience & Service

Academic Appointments

Other Appointments/Responsibilities

Honors & Awards

Professional Memberships

Selected Publications

Peer-Reviewed Articles

Invited Articles

Other Articles

Editorials

Book Chapters

Patents

Selected Presentations & Talks

Local Presentations

Regional Presentations

National Presentations

International Presentations

Formal Peers

Grant & Contract Support

Patient Reviews

Related Links

Care Centers and Clinics

Departments and Divisions

Labs

Help #EndCancer

Tinsu Pan, Ph.D.

About Dr. Tinsu Pan

Present Title & Affiliation

Primary Appointment

Education & Training

Degree-Granting Education

Postgraduate Training

Board Certifications

Experience & Service

Academic Appointments

Other Appointments/Responsibilities

Honors & Awards

Professional Memberships

Selected Publications

Peer-Reviewed Articles

Invited Articles

Other Articles

Editorials

Book Chapters

Patents

Selected Presentations & Talks

Local Presentations

Regional Presentations

National Presentations

International Presentations

Formal Peers

Grant & Contract Support

Patient Reviews

Request an Appointment

Related Links

Care Centers and Clinics

Departments and Divisions

Labs

Clinical Trials

Help #EndCancer

Give Now

Donate Blood

Volunteer