Tze Yee Lim, PhD
Department of Radiation Physics, Division of Radiation Oncology
Present Title & Affiliation
Primary Appointment
Full Member of the Medical Physics Program, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas
Associate Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2016 | University of Texas MD Anderson Cancer Center, US, Ph.D. in Medical Physics |
| 2011 | Drexel University, US, B.S. in Physics (Minor: Mathematics) |
Postgraduate Training
| 2016-2018 | Clinical Residency, Therapeutic Medical Physics, University of California San Diego, San Diego, California |
Licenses & Certifications
| 2019 | Medical Physicist License |
| 2019 | American Board of Radiology |
| 2011 | Certificate in Medical Humanities |
Experience & Service
Faculty Academic Appointments
Associate Member of the Medical Physics Program, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, TX, 2020 - 2025
Assistant Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2018 - 2024
Institutional Committee Activities
Member, ROSI Boot Walk Trainee Seed Award Review Committee, 2024 - Present
HLMS Physics Representative, Quality and Safety Committee, 2024 - Present
Member, Medical Physics Program Steering Committee, 2023 - Present
Radiation Physics Research Liaison, Radiation Oncology Clinical Research Council, 2021 - Present
Senator, Faculty Senate, 2020 - 2023
Honors & Awards
| 2018 | Finalist in Young Investigators Symposium, AAPM Spring Clinical Meeting |
| 2017 | 2nd Place in Norm Baily Award (Postdoc/Resident Division), AAPM Southern California Chapter Meeting |
| 2017 | Research Presentation Award, University of California San Diego Research Symposium |
| 2015 | 3rd Place in Research Presentation Award, University of Texas MD Anderson Cancer Center Graduate Student Research Retreat |
| 2015 | 4th Place in Young Investigators Symposium, AAPM Southwest Chapter Meeting |
| 2014 | 2nd Place in Grant Proposal Presentation, University of Texas MD Anderson Cancer Center Graduate Student Research Retreat |
| 2013 | 3rd Place in Young Investigators Symposium, AAPM Southwest Chapter Meeting |
| 2013 | Graduate Scholarship, Cancer Prevention Research Institute of Texas (CPRIT) |
| 2011 | Med-Into-Grad Post-Graduate Fellowship, Howard Hughes Medical Institute (HHMI) |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2022. Total Body/Marrow Irradiation at MD Anderson Cancer Center. Invited. Medical Physics Seminar, US.
- 2021. Total Body Irradiation. Invited. Court Research Group, US.
- 2020. Radiation Therapy in Malaysia and Singapore. Invited. Court Research Group, US.
- 2020. Head and Neck, Lymphoma, Melanoma, Sarcoma (HLMS) Physics. Invited. Faculty and Professional Staff Meeting, US.
- 2019. Varian RapidPlan Knowledge-Based Planning in the Clinic. Invited. Court Research Group, US.
Regional Presentations
- 2022. Total Body Irradiation and Total Marrow Irradiation. Invited, US.
- 2021. Total Body Irradiation. Invited, US.
National Presentations
- 2023. Intensity-Modulated Total Body/Marrow Irradiation. Invited, US.
- 2023. Clinical Implementation of VMAT-TMI (Total Marrow Irradiation). Invited, US.
- 2018. Characterization of the Halcyon SX1 Multi-Leaf Collimator System. Conference, US.
- 2017. Beyond Mere Geometry: Clinically-oriented Contour Evaluation using Knowledge-based Planning. Conference, US.
- 2016. MR Sequences for Post-implant Dosimetry: The MD Anderson Experience. Invited, US.
- 2015. Initial Patient Experience With Positive-Contrast MRI Markers for Low-Dose-Rate Prostate Brachytherapy. Conference, US.
- 2015. Sirius Markers for MRI-based Post-Implant Dosimetry: Initial Patient Experience. Conference, US.
- 2015. MR Protocol Development to Visualize Sirius MRI Markers in Prostate Brachytherapy Patients for MR Based Post-Implant Dosimetry. Conference, US.
- 2014. Sirius MRI Markers for Prostate Post-Implant Assessment: MR Protocol Development. Conference, US.
- 2013. MRI Characteristics of Cobalt Dichloride N-Acetyl Cysteine (C4) as a Contrast Agent Marker for Prostate Brachytherapy. Conference, US.
- 2013. Relaxivity Measurements of Cobalt Dichloride N-Acetyl Cysteine for MRI-based Prostate Brachytherapy. Conference, US.
International Presentations
- 2023. Clinical Implementation of VMAT for Total Marrow Irradiation using Raystation. Conference. Vienna, AT.
- 2018. Clinical Advances in Medical Physics. Invited. Kuala Lumpur, MY.
- 2018. Medical Physics Residency in the United States. Invited. Penang, MY.
Selected Publications
Peer-Reviewed Articles
- Lim TY, Luo D, Moradi-Kurdestany J, Wang X, Tailor R. Film measurements of kilovoltage x-ray percentage depth doses for different energies and field sizes. Br J Radiol 98(1172):1298-1304, 2025. e-Pub 2025. PMID: 40424360.
- Wang H, Yang J, Lee A, Phan J, Lim TY, Fuller CD, Han EY, Rhee DJ, Salzillo T, Zhao Y, Chopra N, Pham M, Castillo P, Sobremonte A, Moreno AC, Reddy JP, Rosenthal D, Garden AS, Wang X. MR-guided stereotactic radiation therapy for head and neck cancers. Clin Transl Radiat Oncol 46, 2024. e-Pub 2024. PMID: 38510980.
- Leone AO, Gronberg MP, Gay S, Govyadinov PA, Beadle BM, Lim TY, Whitaker TJ, Hoffman KE, Court LE, Cao W. A comparison of knowledge-based dose prediction approaches to assessing head and neck radiotherapy plan quality. medRxiv. e-Pub 2024.
- Hughes N, Salzillo TC, Vedam S, Lim TY, Wang X, Wang H, Mohammedsaid M, Fuller CD, Wang J, Yang J. A look-up-table development to facilitate CT simulation of MR-Linac treatment. Phys Imaging Radiat Oncol 29:100524, 2024. e-Pub 2024. PMID: 38192414.
- Parsons D, Lim TY, Teruel JR, Agostinelli S, Liang J, Mancosu P, Cherpak A, Stanley D, Ahn K, Guo B, Gonzalez Y, Gu X, Kim G. Considerations for intensity modulated total body or total marrow and lymphoid irradiation. Clinical and Translational Radiation Oncology 13, 2023. e-Pub 2023. PMID: 37753462.
- Contrera KJ, Phan J, Waguespack SG, Aldehaim M, Wang X, Lim TY, Roberts DB, Fuller C, Spiotto MT, Raza SM, DeMonte F, Hanna EY, Su SY. Prevalence of pituitary hormone dysfunction following radiotherapy for sinonasal and nasopharyngeal malignancies. Head and Neck 45(10):2525-2532, 2023. e-Pub 2023. PMID: 37534890.
- Gronberg M, Jhingran A, Netherton T, Gay SS, Cardenas CE, Chung CV, Fuentes DA, Fuller CD, Howell RM, Khan M, Lim TY, Marquez B, Olanrewaju A, Peterson CB, Vazquez I, Whitaker TJ, Wooten ZT, Yang M, Court LE. Deep learning–based dose prediction to improve the plan quality of volumetric modulated arc therapy for gynecologic cancers. Medical physics 50(11):6639-6648, 2023. e-Pub 2023. PMID: 37706560.
- El-Habashy, D, Wahid, K, He, R, McDonald, B, Rigert, J, Mulder, S, Lim, TY, Wang, X, Yang, J, Ding, Y, Naser, M, Ng, SP, Bahig, H, Salzillo, TC, Preston, KE, Abobakr, M, Shehata, MA, Elkhouly, EA, Alagizy, HA, Hegazy, AH, Mohammadseid, M, Terhaard, CH, Philippens, ME, Rosenthal, DI, Wang, J, Lai, SY, Dresner, A, Christodouleas, JP, Mohamed, AS, Fuller, C. Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system. Clinical and Translational Radiation Oncology 42, 2023. e-Pub 2023. PMID: 37583808.
- El-Habashy DM, Wahid KA, He R, McDonald B, Rigert J, Mulder SJ, Lim TY, Wang X, Yang J, Ding Y, Naser MA, Ng SP, Bahig H, Salzillo TC, Preston KE, Abobakr M, Shehata MA, Elkhouly EA, Alagizy HA, Hegazy AH, Mohammadseid M, Terhaard C, Philippens M, Rosenthal DI, Wang J, Lai SY, Dresner A, Christodouleas JC, Mohamed A, Fuller CD. Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5 T MR-linear accelerator hybrid system. Clinical and Translational Radiation Oncology 42, 2023. e-Pub 2023. PMID: 37205359.
- Gronberg M, Beadle BM, Garden AS, Skinner H, Gay SS, Netherton T, Cao W, Cardenas CE, Chung CV, Fuentes DA, Fuller C, Howell RM, Jhingran A, Lim TY, Marquez B, Mumme R, Olanrewaju A, Peterson CB, Vazquez I, Whitaker TJ, Wooten ZT, Yang M, Court LE. Deep Learning–Based Dose Prediction for Automated, Individualized Quality Assurance of Head and Neck Radiation Therapy Plans. Practical radiation oncology 13(3):e282-e291, 2023. e-Pub 2023. PMID: 36697347.
- Lim TY, Mirkovic D, Wang X, Tailor R. Devices for dosimetric measurements and quality assurance of the Xstrahl 300 orthovoltage unit. J Appl Clin Med Phys 22(4):151-157, 2021. e-Pub 2021. PMID: 33733608.
- Christopherson KM, Gunther JR, Fang P, Peterson SL, Roach KE, Wong PF, Mirkovic D, Lim TY, Wang H, Wang XA, Wang C, Garcia J, Dabaja BS, Pinnix CC. Decreased heart dose with deep inspiration breath hold for the treatment of gastric lymphoma with IMRT. Clin Transl Radiat Oncol 24:79-82, 2020. e-Pub 2020. PMID: 32642563.
- Lim TY, Dragojevic I, Hoffman D, Flores-Martinez E, Kim GY. Characterization of the HalcyonTM multileaf collimator system. J Appl Clin Med Phys 20(4):106-114, 2019. e-Pub 2019. PMID: 30889312.
- Lim TY, Gillespie E, Murphy J, Moore KL. Clinically Oriented Contour Evaluation Using Dosimetric Indices Generated From Automated Knowledge-Based Planning. Int J Radiat Oncol Biol Phys 103(5):1251-1260, 2019. e-Pub 2019. PMID: 30508619.
- Lloyd SAM, Lim TY, Fave X, Flores-Martinez E, Atwood TF, Moiseenko V. TG-51 reference dosimetry for the Halcyon™: A clinical experience. J Appl Clin Med Phys 19(4):98-102, 2018. e-Pub 2018. PMID: 29785729.
- Lim TY, Kudchadker RJ, Wang J, Stafford RJ, MacLellan C, Rao A, Ibbott GS, Frank SJ. Effect of pulse sequence parameter selection on signal strength in positive-contrast MRI markers for MRI-based prostate postimplant assessment. Med Phys 43(7):4312, 2016. e-Pub 2016. PMID: 27370146.
- Lim TY, Kudchadker RJ, Wang J, Bathala T, Szklaruk J, Pugh TJ, Mahmood U, Ibbott GS, Frank SJ. Development of a magnetic resonance imaging protocol to visualize encapsulated contrast agent markers in prostate brachytherapy recipients: initial patient experience. J Contemp Brachytherapy 8(3):235-42, 2016. e-Pub 2016. PMID: 27504133.
- Dhanesar SK, Lim TY, Du W, Bruno TL, Frank SJ, Kudchadker RJ. Evaluation of the MIM Symphony treatment planning system for low-dose-rate- prostate brachytherapy. J Appl Clin Med Phys 16(5):62–75, 2015. e-Pub 2015. PMID: 26699290.
- Lim TY, Stafford RJ, Kudchadker RJ, Sankaranarayanapillai M, Ibbott G, Rao A, Martirosyan KS, Frank SJ. MRI characterization of cobalt dichloride-N-acetyl cysteine (C4) contrast agent marker for prostate brachytherapy. Phys Med Biol 59(10):2505-16, 2014. e-Pub 2014. PMID: 24778352.
- Chen X, Hu X, Lim TY, Shen X, Park EK, Rosen GL. Exploiting the functional and taxonomic structure of genomic data by probabilistic topic modeling. IEEE/ACM Trans Comput Biol Bioinform 9(4):980-91, 2012. e-Pub 2012. PMID: 21844637.
- Rosen GL, Lim TY. NBC update: The addition of viral and fungal databases to the Naïve Bayes classification tool. BMC Res Notes 5(81), 2012. e-Pub 2012. PMID: 22293603.
Review Articles
- Gronberg M, Netherton T, Beadle B, Cao W, Cardenas C, Chung C, Fuller CD, Garcia J, Hancock D, Howell RM, Jhingran A, Lee A, Lim TY, Moreno AC, Olanrewaju N, Peterson C, Whitaker TJ, Court LE. Radiotherapy Plan Quality Assessment: Current Tools and Future Directions. African Journal of Medical Physics 4(1):27-40, 2023. e-Pub 2023.
Abstracts
- Lim TY, Wang X. Performance of large longitudinal shifts on treatment couches with automatic couch compensation, 2024. e-Pub 2024.
- Gronberg M, Beadle BM, Fuller CD, Gay S, Netherton TJ, Wood J, Cardenas CE, Peterson C, Lim TY, Howell RM, Jhingran A, Court LE. Three-dimensional dose prediction for radiotherapy plan review in a clinical trial setting, 2024. e-Pub 2024.
- Wang H, Lim TY, Yang J, Fuller CD, Phan J, Wang X. Optimizing Radiation Treatment for Head and Neck Cancer with Adapt-to-Shape Planning on a 1.5T MR-Linac, 2023. e-Pub 2023.
- Wang X, Tailor R, Lim TY, Dabaja B, Gunther J, Rougeau T, Pinnix C, Fang P, Wu S, Wang C. Simple AP/PA techniques to deliver total skin electron beam therapy to frail patient while recumbent, 2023. e-Pub 2023.
- Yoder A, Netherton T, Wang X, Lim TY, Wang H, Luo D, Wang C, Thrower S, Farooqi A, Mitra D, Bishop A, Guadagnolo A. Evaluating the Utility of Traditional Bowel Dose Constraints when Treating Abdominal and Pelvic Sarcomas with Preoperative Radiation Therapy, 2023. e-Pub 2023.
- Schrank B, Manzar G, Wu S, Gunther J, Fang P, Jabbour E, Lim TY, Daver N, Cykowski M, Fuller G, Cachia D, Kamiya-Matsuoka C, Woodman K, DiNardo C, Jain N, Short N, Sasaki K, Dabaja B, Kantarjian H, Pinnix C. Dorsal Column Myelopathy Following Intrathecal Chemotherapy for Leukemia, 2023. e-Pub 2023.
- Lim TY, Wu S, Fang P, Dabaja B, Ohrt J, Gunther J, Pinnix C, Rougeau T, Sobremonte A, Wang C, Netherton T, Champlin R, Reisner Y, Shpall E, Wang X. Clinical Implementation of VMAT for Total Marrow Irradiation using Raystation, 2023. e-Pub 2023.
- Salzillo T, Hughes N, Vedam S, Lim TY, Wang X, Wang H, Mohammedsaid M, Fuller CD, Wang J, Yang J. Clinical Development of CT Simulations for MR-Linac Patients without the Use of a CT Table Overlay, 2023. e-Pub 2023.
- Wang H, Rhee DJ, Gao S, Balter P, Phan J, Lee A, Thrower S, Laneave S, Ellison D, Schipull E, Hurtt R, Netherton T, Lim TY, Mirkovic D, Luo D, Wang C, Tailor R, Wong PF, Wang X. Comparison of flattening filter free (FFF) and flattening filter (FF) photon beam VMAT plans for head and neck stereotactic body radiotherapy, 2023. e-Pub 2023.
- Wang H, Chen X, Zhao Y, Wang X, Han E, Lim TY, Yu Z, Prajapati S, Yang J. Evaluation of Delivered Dose Using Synthetic CT for MR-Guided and CT-Guided Radiotherapy, 2022. e-Pub 2022.
- Jacinto JC, Lim TY, Wang X, Briere TM, McGovern SL, Paulino A. Feasibility of Deep Inspiration Breath Hold Technique and Local Control in Pediatric Hodgkin Lymphoma, 2022. e-Pub 2022.
- Wang H, Han E, Phan J, Lim TY, Yang J, Pham M, Wang X. Feasibility of Stereotactic Radiotherapy for Base of Tongue Cancers On the MR-Linac, 2022. e-Pub 2022.
- Gronberg M, Gay S, Beadle B, Garden A, Skinner H, Netherton T, Cao W, Vazquez I, Olanrewaju A, Chung C, Cardenas C, Fuller C, Peterson C, Jhingran A, Howell R, Lim TY, Yang M, Mumme R, Court L. Deep Learning-Based Dose Prediction for Automated, Individualized Quality Assurance of Head and Neck Radiotherapy Plans, 2022. e-Pub 2022.
- Prajapati S, Yu Z, Zhao Y, Lim TY, Wang H, Wang X, Lee B, Castillo P, Sobremonte A, Farooqi A, Mitra D, Kudchadker R, Tang C, Yang J. Quantifying Setup Uncertainties in Treating Intramuscular Metastases with Image-Guided Radiation Therapy, 2022. e-Pub 2022.
- Manzar GS, Wu S, Khan M, Corrigan KL, Yoder AK, Gunther JR, Thomas S, Manasanch EE, Lee H, Lim TY, Amini B, Lin P, Orlowski R, Patel K, Becnel MR, Kaufman G, Weber D, Dabaja B, Pinnix CC, Fang P. Outcome of Patients with Central Nervous System Multiple Myeloma (CNS-MM) Treated with CNS-Directed Radiation Therapy, 2022. e-Pub 2022.
- H Wang, J Yang, J Phan, E Han, Lim TY, P Castillo, X Wang. Feasibility of Skull Base Stereotactic Radiotherapy on Elekta MR-Linac, 2021. e-Pub 2021.
- Lim TY, Wang X, Yang J. Scoring Contour Agreement Using a Beta Distribution Model, 2020. e-Pub 2020.
- Cardenas C, Beadle B, Lim TY, Yang J, Olanrewaju A, Douglas R, Netherton T, Zhang L, Court L. Head and Neck CTV Decision Making and Automatic Contouring Results in More Consistent Radiotherapy Plans, 2020. e-Pub 2020.
- Lloyd S, Lim TY, Fave X, Flores-Martinez E, Moiseenko V, Moore K, Atwood T. A Simplified Commissioning Procedure for the Halcyon Linear Accelerator, 2018. e-Pub 2018.
- Lim TY, Dragojevic I, Hoffman DB, Flores-Martinez E, Kim G. Characterization of the Halcyon SX1 Multi-Leaf Collimator System, 2018. e-Pub 2018.
- Kim G, Rah J, Lim TY, Flores-Martinez E, Pawlicki T. Feasibility Study of the Image-based Automatic QA for the Halcyon, 2018. e-Pub 2018.
- Lim TY, Flores-Martinez E, Fave X, Lloyd S, Dragojevic I, Hoffman D, Atwood T, Moore K, Kim G. Initial Investigation of the SX1 Dual-Layer Multileaf Collimator Tongue-and-Groove Effect, 2018. e-Pub 2018.
- Lloyd S, Lim TY, Fave X, Flores-Martinez E, Atwood T, Moore K, Moiseenko V. Halcyon: Commissioning and the first 100 patients, 2018. e-Pub 2018.
- Lim TY, Gillespie EF, Murphy JD, Moore KL. Dosimetric Indices from Automated Planning versus Geometric Conformity Indices for the Evaluation of Contour Accuracy in Head-and-Neck Cancer, 2017. e-Pub 2017.
- Lim TY, Gillespie EF, Li N, Ziemer B, Sherer M, Murphy JD, Moore KL. Dosimetric Impact of Contour Variation in Head-and-Neck Anatomy, 2017. e-Pub 2017.
- Lim TY, Gillespie EF, Murphy J, Moore KL. Beyond Mere Geometry: Clinically-oriented Contour Evaluation using Knowledge-based Planning, 2017. e-Pub 2017.
- Martin GV, Pugh TJ, Mahmood U, Swanson DA, Lim TY, Kudchadker R, Graber W, Wang J, Bruno T, Bathala TK, Blanchard P, Frank SJ. Are We Ready to Replace Post-Implant CT Dosimetry? Permanent Prostate Brachytherapy Post-Implant MRI Dosimetry Using Positive Contrast MRI Markers, 2016. e-Pub 2016.
- Blanchard P, Pugh TJ, Mahmood U, Swanson DA, Graber WJ, Wang J, Bathala TK, Lim TY, Bruno T, Martin GV, Kudchadker RJ, Frank SJ. MRI Simulation for LDR Prostate Brachyhtherapy: Can We Replace Ultrasound with MRI for Treatment Planning? Comparison of Pre-Planning, Day 0 and Day 30 MR Dosimetry, 2016. e-Pub 2016.
- Lim TY, Wang J, Frank SJ, Stafford RJ, Bruno T, Bathala T, Mahmood U, Pugh TJ, Ibbott G, Kudchadker RJ. MR Protocol Development to Visualize Sirius MRI Markers in Prostate Brachytherapy Patients for MR Based Post-Implant Dosimetry, 2015. e-Pub 2015.
- Lim TY, Kudchadker R, Wang J, Stafford RJ, Bruno T, Bathala T, Mahmood U, Pugh TJ, Ibbott G, Frank SJ. Sirius Markers for MRI-based Post-Implant Dosimetry: Initial Patient Experience, 2015. e-Pub 2015.
- Lim TY, Kudchadker R, Wang J, Stafford RJ, Bruno T, Bathala T, Mahmood U, Pugh TJ, Ibbott G, Frank SJ. Initial Patient Experience With Positive-Contrast MRI Markers for Low-Dose-Rate Prostate Brachytherapy, 2015. e-Pub 2015.
- Wang J, Lim TY, Kudchadker R, Pugh T, Ibbott G, Frank S. Evaluation of MR Image Distortion in Positive Contrast Markers for Low-Dose Prostate Brachytherapy, 2015. e-Pub 2015.
- Lim TY, Wang J, Kudchadker RJ, Stafford RJ, Bathala T, Pugh TJ, Ibbott G, Frank SJ. Sirius MRI Markers for Prostate Post-Implant Assessment: MR Protocol Development, 2014. e-Pub 2014.
- Kudchadker RJ, Lim TY, Du W, Bruno TL, Mahmood U, Pugh TJ, Frank SJ. 131Cs Stranded-Seed Nomogram for a Prospective Phase II Intermediate-Risk Low-Dose-Rate Prostate Brachytherapy Clinical Trial, 2013. e-Pub 2013.
- Lim TY, Stafford RJ, Sankarayanapillai M, Kudchadker RJ, Frank SJ. Relaxivity Measurements of Cobalt Dichloride N-Acetyl Cysteine for MRI-based Prostate Brachytherapy, 2013. e-Pub 2013.
- Lim TY, Stafford RJ, Sankaranarayanapillai M, Martirosyan M, Kudchadker RJ, Frank SJ. MRI Characteristics of Cobalt Dichloride N-Acetyl Cysteine (C4) as a Contrast Agent Marker for Prostate Brachytherapy, 2013. e-Pub 2013.
- Lim TY, Frank SJ, Pugh TJ, Bruno TL, Kudchadker RJ. Comparison of Two Commercial Treatment Planning Systems VariSeed and MIM for Low Dose Rate Prostate Brachytherapy, 2013. e-Pub 2013.
- Lim TY, Ma JF. Image-based determination of the fat signal model for Dixon water and fat imaging, 2012. e-Pub 2012.
- Lim TY, Rosen GL. Random Indexing to Reduce Feature Dimensions Used in Taxonomic Classification of Next-generation Reads, 2010. e-Pub 2010.
Patient Reviews
CV information above last modified September 11, 2025