Uwe Titt, Ph.D.
Department of Radiation Physics, Division of Radiation Oncology
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Radiation Physics - Patient Care, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
1999 | Johann Wolfgang Goethe Universität, Frankfurt, DEU, PHD, Nuclear Physics |
1994 | Johann Wolfgang Goethe Universitӓt, Frankfurt, DEU, Diploma examination, Nuclear Physics |
1991 | Johann Wolfgang Goethe Universitӓt, Frankfurt, DEU, Pre-examination Diploma, Pre-examination |
Postgraduate Training
1999-2000 | Post-Doctoral Fellow, Neutron Dosimetry, Massachusetts General Hospital, Boston, MA |
Experience & Service
Academic Appointments
Assistant Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2003 - 2010
Instructor, Department of Radiation Oncology, Division of Unknown, Massachusetts General Hospital, Boston, MA, 2000 - 2003
Teaching Assistant, Department of Bio-Chemistry, Division of Unknown, Technische Universität, Braunschweig, 1997 - 1999
Instructor, Department of Bio-Chemistry, Division of Unknown, Technische Universität, Braunschweig, 1997 - 1999
Instructor, Department of Nuclear Physics, Division of Unknown, Johann Wolfgang Goethe Universität, Frankfurt, 1993 - 1994
Other Appointments/Responsibilities
Staff Scientist, Biochemistry, Technische Universität, Braunschweig, 1997 - 1999
Nuclear Physicist, Weizmann Institute of Science Rehovot, Rehovot, 1994 - 1995
Honors & Awards
1999 | Helmholtz Prize, Physikalisch Technische Bundesanstalt, Braunschweig, Germany |
Selected Publications
Peer-Reviewed Articles
- Mairani A, Mein S, Blakely E, Debus J, Durante M, Ferrari A, Fuchs H, Georg D, Grosshans DR, Guan F, Haberer T, Harrabi S, Horst F, Inaniwa T, Karger CP, Mohan R, Paganetti H, Parodi K, Sala P, Schuy C, Tessonnier T, Titt U, Weber U. Roadmap: helium ion therapy. Phys Med Biol 67(15), 2022. e-Pub 2022. PMID: 35395649.
- Yang M, Wang X, Guan F, Titt U, Iga K, Jiang D, Takaoka T, Tootake S, Katayose T, Umezawa M, Schüler E, Frank S, Lin SH, Sahoo N, Koong AC, Mohan R, Zhu XR. Adaptation and dosimetric commissioning of a synchrotron-based proton beamline for FLASH experiments. Phys Med Biol 67(16), 2022. e-Pub 2022. PMID: 35853442.
- Wang Q, Titt U, Mohan R, Guan F, Zhao Y, Yang M, Yepes P. Optimization of FLASH proton beams using a track-repeating algorithm. Med Phys. e-Pub 2022. PMID: 35900902.
- Manandhar M, Bright SJ, Flint DB, Martinus DKJ, Kolachina RV, Kacem MB, Titt U, Martin TJ, Lee CL, Morrison K, Shaitelman SF, Sawakuchi GO. Effect of boron compounds on the biological effectiveness of proton therapy. Med Phys. e-Pub 2022. PMID: 35754208.
- Titt U, Yang M, Wang X, Iga K, Fredette N, Schueler E, Lin SH, Zhu XR, Sahoo N, Koong AC, Zhang X, Mohan R. Design and validation of a synchrotron proton beam line for FLASH radiotherapy preclinical research experiments. Med Phys 49(1):497-509, 2022. e-Pub 2021. PMID: 34800037.
- Meyer HJ, Titt U, Mohan R. Monte Carlo study of the mechanism of proton-boron fusion therapy. Med Phys 49(1):579-582, 2022. e-Pub 2021. PMID: 34822721.
- Bronk L, Guan F, Patel D, Ma D, Kroger B, Wang X, Tran K, Yiu J, Stephan C, Debus J, Abdollahi A, Jäkel O, Mohan R, Titt U, Grosshans DR. Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques. Cancers (Basel) 12(12), 2020. e-Pub 2020. PMID: 33291477.
- Titt U, Pera E, Gillin MT. Monte Carlo Simulations of Neutron Ambient Dose Equivalent in a Novel Proton Therapy Facility Design. Int J Part Ther 6(4):29-37, 2020. e-Pub 2020. PMID: 32582817.
- Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO. Non-homologous end joining is more important than proton linear energy transfer in dictating cell death. Int J Radiat Oncol Biol Phys 105(5):1119-1125, 2019. e-Pub 2019. PMID: 31425731.
- Yepes P, Adair A, Frank SJ, Grosshans DR, Liao Z, Liu A, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy. Adv Radiat Oncol 4(1):156-167, 2019. e-Pub 2018. PMID: 30706024.
- Newpower M, Schuemann J, Mohan R, Paganetti H, Titt U. Comparing 2 Monte Carlo Systems in Use for Proton Therapy Research. International Journal of Particle Therapy 6(1):18-28, 2019.
- Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Erratum: "Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code" [Med. Phys. 42 (11), page range 6234-6247(2015)]. Med Phys 45(3):1302, 2018. e-Pub 2018. PMID: 29527697.
- Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Erratum: "Monte Carlo simulations of 3 He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness" [Med. Phys. 43 (2), page range 761-776(2016)]. Med Phys 45(3):1301, 2018. e-Pub 2018. PMID: 29527699.
- Yepes P, Adair A, Grosshans D, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy. Phys Med Biol 63(4):045003, 2018. e-Pub 2018. PMID: 29339570.
- Guan F, Geng C, Ma D, Bronk L, Kerr M, Li Y, Gates D, Kroger B, Sahoo N, Titt U, Grosshans D, Mohan R. RBE Model-Based Biological Dose Optimization for Proton Radiobiology Studies. Int J Part Ther 5(1):160-171, 2018. e-Pub 2018. PMID: 30338268.
- Titt U, Suzuki K, Li Y, Sahoo N, Gillin MT, Zhu XR. Technical Note: Dosimetric characteristics of the ocular beam line and commissioning data for an ocular proton therapy planning system at the Proton Therapy Center Houston. Med Phys 44(12):6661-6671, 2017. e-Pub 2017. PMID: 28975637.
- Patel D, Bronk L, Guan F, Peeler CR, Brons S, Dokic I, Abdollahi A, Rittmüller C, Jäkel O, Grosshans D, Mohan R, Titt U. Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams. Med Phys 44(11):6061-6073, 2017. e-Pub 2017. PMID: 28880368.
- Niedzielski JS, Yang J, Mohan R, Titt U, Mirkovic D, Stingo F, Liao Z, Gomez DR, Martel MK, Briere TM, Court LE. Differences in Normal Tissue Response in the Esophagus Between Proton and Photon Radiation Therapy for Non-Small Cell Lung Cancer Using In Vivo Imaging Biomarkers. Int J Radiat Oncol Biol Phys 99(4):1013-1020, 2017. e-Pub 2017. PMID: 29063837.
- Wu RY, Liu AY, Sio TT, Blanchard P, Wedges C, Amin MV, Gunn GB, Titt U, Ye R, Suzuki K, Gillin MT, Zhu XR, Mohan R, Frank SJ. Intensity Modulated Proton Therapy Adaptive Planning for Patients with Oropharyngeal Cancer. Int J Part Ther 4(2):26-34, 2017.
- Peeler CR, Mirkovic D, Titt U, Blanchard P, Gunther JR, Mahajan A, Mohan R, Grosshans DR. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiother Oncol 121(3):395-401, 2016. e-Pub 2016. PMID: 27863964.
- Mikell J, Cheenu Kappadath S, Wareing T, Erwin WD, Titt U, Mourtada F. Evaluation of a deterministic grid-based boltzmann solver (GBBS) for voxel-level absorbed dose calculations in nuclear medicine. Phys Med Biol 61(12):4564-4582, 2016. e-Pub 2016. PMID: 27224727.
- Yepes PP, Eley JG, Liu A, Mirkovic D, Randeniya S, Titt U, Mohan R. Validation of a track repeating algorithm for intensity modulated proton therapy: clinical cases study. Phys Med Biol 61(7):2633-2645, 2016. e-Pub 2016. PMID: 26961764.
- Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Monte Carlo simulations of 3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Med Phys 43(2):761-776, 2016. PMID: 26843239.
- Yepes P, Guan F, Kerr M, Randeniya S, Li Y, Bronk L, Liu A, Mirkovic D, Sahoo N, Titt U, Mohan R. Validation of a track-repeating algorithm versus measurements in water for proton scanning beams. Biomed Phys Eng Express, 2016.
- Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Analysis of the Track and Dose Averaged LET and LET Spectra in Proton Therapy using the Geant4 Monte Carlo Code. Med Phys 42(11):6234-6247, 2015. e-Pub 2015. PMID: 26520716.
- Titt U, Sell M, Unkelbach J, Bangert M, Mirkovic D, Oelfke U, Mohan R. Degradation of proton depth dose distributions attributable to microstructures in lung-equivalent material. Med Phys 42(11):6425-6432, 2015. PMID: 26520732.
- Cao W, Zaghian M, Randeniya K, Lim G, Titt U, Mohan R. An Investigation of Including Variable Relative Biological Effectiveness in Intensity Modulated Proton Therapy Planning Optimization for Head and Neck Cancer Patients. Med Phys 42(6):3356, 2015. PMID: 26127776.
- Guan F, Titt U, Patel D, Bronk L, Taleei R, Peeler C, Mirkovic D, Grosshans D, Jӓkel O, Mohan R. Experimental Design for High-Throughput In-Vitro RBE Measurements Using Protons, Helium and Carbon Ions. Med Phys 42(6):3675, 2015. PMID: 26129285.
- Guan F, Bronk L, Titt U, Lin SH, Mirkovic D, Kerr MD, Zhu XR, Dinh J, Sobieski M, Stephan C, Peeler CR, Taleei R, Mohan R, Grosshans DR. Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy. Sci Rep 5(9850):9850, 2015. e-Pub 2015. PMID: 25984967.
- Perles LA, Mirkovic D, Anand A, Titt U, Mohan R. LET dependence of the response of EBT2 films in proton dosimetry modeled as a bimolecular chemical reaction. Phys Med Biol 58(23):8477-91, 2013. e-Pub 2013. PMID: 24240474.
- Cho J, Ibbott G, Gillin M, Gonzalez-Lepera C, Titt U, Paganetti H, Kerr M, Mawlawi O. Feasibility of proton-activated implantable markers for proton range verification using PET. Phys Med Biol 58(21):7497-7512, 2013. e-Pub 2013. PMID: 24099853.
- Newhauser WD, Rechner L, Mirkovic D, Yepes P, Koch NC, Titt U, Fontenot JD, Zhang R. Benchmark measurements and simulations of dose perturbations due to metallic spheres in proton beams. Radiat Meas 58:37-44, 2013. e-Pub 2013. PMID: 25147474.
- Zhu XR, Poenisch F, Lii M, Sawakuchi GO, Titt U, Bues M, Song X, Zhang X, Li Y, Ciangaru G, Li H, Taylor MB, Suzuki K, Mohan R, Gillin MT, Sahoo N. Commissioning dose computation models for spot scanning proton beams in water for a commercially available treatment planning system. Med Phys 40(4):041723, 2013. PMID: 23556893.
- Titt U, Bednarz B, Paganetti H. Comparison of MCNPX and Geant4 proton energy deposition predictions for clinical use. Phys Med Biol 57(20):6381-93, 2012. e-Pub 2012. PMID: 22996039.
- Yang M, Zhu XR, Park PC, Titt U, Mohan R, Virshup G, Clayton JE, Dong L. Comprehensive analysis of proton range uncertainties related to patient stopping-power-ratio estimation using the stoichiometric calibration. Phys Med Biol 57(13):4095-4115, 2012. e-Pub 2012. PMID: 22678123.
- Peeler CR, Titt U. Monte Carlo study of radial energy deposition from primary and secondary particles for narrow and large proton beamlet source models. Phys Med Biol 57(12):3785-3792, 2012. e-Pub 2012. PMID: 22617113.
- Anand A, Sahoo N, Zhu XR, Sawakuchi GO, Poenisch F, Amos RA, Ciangaru G, Titt U, Suzuki K, Mohan R, Gillin MT. A procedure to determine the planar integral spot dose values of proton pencil beam spots. Med Phys 39(2):891-900, 2012. PMID: 22320798.
- Yepes PP, Brannan T, Huang J, Mirkovic D, Newhauser WD, Taddei PJ, Titt U. Application of a fast proton dose calculation algorithm to a thorax geometry. Radiation Measurements 45(10):1367-1368, 2010. PMID: 21544230.
- Titt U, Mirkovic D, Sawakuchi GO, Perles LA, Newhauser WD, Taddei PJ, Mohan R. Adjustment of the lateral and longitudinal size of scanned proton beam spots using a pre-absorber to optimize penumbrae and delivery efficiency. Phys Med Biol 55(23):7097-7106, 2010. e-Pub 2010. PMID: 21076194.
- Fontenot JD, Bloch C, Followill D, Titt U, Newhauser WD. Estimate of the uncertainties in the relative risk of secondary malignant neoplasms following proton therapy and intensity-modulated photon therapy. Phys Med Biol 55(23):6987 - 6998, 2010. PMID: 21076196.
- Sawakuchi GO, Mirkovic D, Perles LA, Sahoo N, Zhu XR, Ciangaru G, Suzuki K, Gillin MT, Mohan R, Titt U. An MCNPX Monte Carlo Model of a Discrete Spot Scanning Proton Beam Therapy Nozzle. Med Phys 37(9):4960-4970, 2010. PMID: 20964215.
- Sawakuchi GO, Sahoo GP, Gasparian P, Rodriguez M, Archambault L, Titt U, Yukihara E. Determination of average LET of therapeutic proton beams using A1203:C optically stimulated luminescence (OSL) detectors. Phys Med Biol 55(17):4963-4976, 2010. PMID: 20693613.
- Perles L, Mirkovic D, Sawakuchi G, Titt U. Monte Carlo Investigation of Rebinning Material Density Distributions of Lung Parenchyma Phantoms in Proton Therapy. Nuclear Technology 175:22-26, 2010.
- Sawakuchi GO, Zhu XR, Poenisch F, Suzuki K, Ciangaru G, Titt U, Anand A, Mohan R, Gillin MT, Sahoo N. Experimental characterization of the low-dose envelope of spot scanning proton beams. Phys Med Biol 55(12):3467-3478, 2010. e-Pub 2010. PMID: 20508318.
- Sawakuchi GO, Titt U, Mirkovic D, Ciangaru G, Zhu XR, Sahoo N, Gillin MT, Mohan R. Monte Carlo investigation of the low-dose envelope from scanned proton pencil beams. Phys Med Biol 55(3):711-721, 2010. e-Pub 2010. PMID: 20071752.
- Gillin MT, Sahoo N, Bues M, Ciangaru G, Sawakuchi G, Poenisch F, Arjomandy B, Martin C, Titt U, Suzuki K, Smith AR, Zhu XR. Commissioning of the discrete spot scanning proton beam delivery system at The University of Texas M.D. Anderson Cancer Center, Proton Therapy Center, Houston. Med Phys 37(1):154-163, 2010. PMID: 20175477.
- Yukihara EG, Gasparian PBR, Sawakuchi GO, Ruan C, Ahmad S, Kalavangunta C, Clouse WJ, Sahoo N and Titt U. Medical applications of optically stimulated luminescence dosimeters (OSLD's). Radiat Meas 45(3-6):658–662, 2010.
- Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Titt U, Woo S, Newhauser WD. Reducing Stray Radiation Dose for a Pediatric Patient Receiving Proton Craniospinal Irradiation. Nucl Technol 168(1):108-112, 2009. PMID: 20865143.
- Kry SF, Salehpour M, Titt U, White RA, Stovall M, Followill D. Monte Carlo study shows no significant difference in second cancer risk between 6- and 18-MV intensity-modulated radiation therapy. Radiother Oncol 91(1):132-7, 2009. e-Pub 2009. PMID: 19147246.
- Vassiliev ON, Kry SF, Chang JY, Balter PA, Titt U, Mohan R. Stereotactic radiotherapy for lung cancer using a flattening filter free Clinac. J Appl Clin Med Phys 10(1):14-21, 2009. e-Pub 2009. PMID: 19223837.
- Vassiliev ON, Wareing TA, Davis IM, McGhee J, Barnett D, Horton JL, Gifford K, Failla G, Titt U, Mourtada F. Feasibility of a multigroup deterministic solution method for three-dimensional radiotherapy dose calculations. Int J Radiat Oncol Biol Phys 72(1):220-227, 2008. PMID: 18722273.
- Sawakuchi GO, Titt U, Mirkovic D, Mohan R. Density heterogeneities and the influence of multiple Coulomb and nuclear scatterings on the Bragg peak distal edge of proton therapy beams. Phys Med Biol 53(17):4605-4619, 2008. e-Pub 2008. PMID: 18678928.
- Titt U, Sahoo N, Ding X, Zheng Y, Newhauser WD, Zhu XR, Polf JC, Gillin MT, Mohan R. Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions. Phys Med Biol 53(16):4455-70, 2008. e-Pub 2008. PMID: 18670050.
- Kry SF, Howell RM, Titt U, Salehpour M, Mohan R, Vassiliev ON. Energy spectra, sources, and shielding considerations for neutrons generated by a flattening filter-free Clinac. Med Phys 35(5):1906-1911, 2008. PMID: 18561666.
- Taddei PJ, Fontenot JD, Zheng Y, Mirkovic D, Lee AK, Titt U, Newhauser WD. Reducing stray radiation dose to patients receiving passively scattered proton radiotherapy for prostate cancer. Phys Med Biol 53(8):2131-2147, 2008. e-Pub 2008. PMID: 18369278.
- Koch N, Newhauser WD, Titt U, Gombos D, Coombes K, Starkschall G. Monte Carlo calculations and measurements of absorbed dose per monitor unit for the treatment of uveal melanoma with proton therapy. Phys Med Biol 53(6):1581-1594, 2008. e-Pub 2008. PMID: 18367789.
- Titt U, Zheng Y, Vassiliev ON, Newhauser WD. Monte Carlo investigation of collimator scatter of proton-therapy beams produced using the passive scattering method. Phys Med Biol 53(2):487-504, 2008. e-Pub 2007. PMID: 18185001.
- Polf JC, Harvey MC, Titt U, Newhauser WD, Smith AR. Initial beam size study for passive scatter proton therapy. I. Monte Carlo verification. Med Phys 34(11):4213-4218, 2007. PMID: 18072485.
- Kry SF, Titt U, Followill D, Pönisch F, Vassiliev ON, White RA, Stovall M, Salehpour M. A Monte Carlo model for out-of-field dose calculation from high-energy photon therapy. Med Phys 34(9):3489-3499, 2007. PMID: 17926952.
- Vassiliev ON, Kry SF, Kuban DA, Salehpour M, Mohan R, Titt U. Treatment-Planning Study of Prostate Cancer Intensity-Modulated Radiotherapy with a Varian Clinac Operated without a Flattening Filter. Int J Radiat Oncol Biol Phys 68(5):1567-1571, 2007. e-Pub 2007. PMID: 17544596.
- Newhauser W, Fontenot J, Zheng Y, Polf J, Titt U, Koch N, Zhang X, Mohan R. Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm. Phys Med Biol 52(15):4569-4584, 2007. e-Pub 2007. PMID: 17634651.
- Kry SF, Titt U, Pönisch F, Vassiliev ON, Salehpour M, Gillin M, Mohan R. Reduced neutron production through use of a flattening-filter-free accelerator. Int J Radiat Oncol Biol Phys 68(4):1260-1264, 2007. PMID: 17637397.
- Fontenot JD, Newhauser WD, Bloch C, White RA, Titt U, Starkschall G. Determination of output factors for small proton therapy fields. Med Phys 34(2):489-498, 2007. PMID: 17388166.
- Vassiliev ON, Titt U, Kry SF, Mohan R, Gillin MT. Radiation safety survey on a flattening filter-free medical accelerator. Radiat Prot Dosimetry 124(2):187-90, 2007. e-Pub 2007. PMID: 17681966.
- Kry SF, Titt U, Pönisch F, Followill D, Vassiliev ON, White RA, Mohan R, Salehpour M. A Monte Carlo model for calculating out-of-field dose from a Varian 6 MV beam. Med Phys 33(11):4405-4413, 2006. PMID: 17153419.
- Pönisch F, Titt U, Vassiliev ON, Kry SF, Mohan R. Properties of unflattened photon beams shaped by a multileaf collimator. Med Phys 33(6):1738-1746, 2006. PMID: 16872081.
- Titt U, Vassiliev ON, Ponisch F, Dong L, Liu H, Mohan R. A flattening filter free photon treatment concept evaluation with Monte Carlo. Med Phys 33(6):1595-1602, 2006. PMID: 16872067.
- Vassiliev ON, Titt U, Pönisch F, Kry SF, Mohan R, Gillin MT. Dosimetric properties of photon beams from a flattening filter free clinical accelerator. Phys Med Biol 51(7):1907-1917, 2006. e-Pub 2006. PMID: 16552113.
- Vassiliev ON, Titt U, Kry SF, Pönisch F, Gillin MT, Mohan R. Monte Carlo study of photon fields from a flattening filter-free clinical accelerator. Med Phys 33(4):820-827, 2006. PMID: 16696457.
- Pönisch F, Titt U, Kry SF, Vassiliev ON, Mohan R. MCNPX simulation of a multileaf collimator. Med Phys 33(2):402-404, 2006. PMID: 16532947.
- Titt U, Vassiliev ON, Ponisch F, Kry SF, Mohan R. Monte Carlo study of backscatter in a flattening filter free clinical accelerator. Med Phys 33(9):3270-3273, 2006. PMID: 17022221.
- Newhauser W, Koch N, Hummel S, Ziegler M, Titt U. Monte Carlo simulations of a nozzle for the treatment of ocular tumours with high-energy proton beams. Phys Med Biol 50(22):5229-5249, 2005. e-Pub 2005. PMID: 16264250.
- Bues M, Newhauser WD, Titt U, Smith AR. Therapeutic step and shoot proton beam spot-scanning with a multi-leaf collimator: a Monte Carlo study. Radiat Prot Dosimetry 115(1-4):164-169, 2005. PMID: 16381706.
- Polf JC, Newhauser WD, Titt U. Patient neutron dose equivalent exposures outside of the proton therapy treatment field. Radiat Prot Dosimetry 115(1-4):154-158, 2005. PMID: 16381704.
- Titt U, Newhauser WD. Neutron shielding calculations in a proton therapy facility based on Monte Carlo simulations and analytical models: criterion for selecting the method of choice. Radiat Prot Dosimetry 115(1-4):144-148, 2005. PMID: 16381702.
- Newhauser WD, Ding X, Giragosian D, Nill S, Titt U. A Neutron radiation area monitoring system for proton therapy facilities. Radiat Prot Dosimetry 115(1-4):149-153, 2005. PMID: 16381703.
- Fontenot JD, Newhauser WD, Titt U. Design tools for proton therapy nozzles based on the double-scattering foil technique. Radiat Prot Dosimetry 31(1-4 Pt 2):1723, 2004. PMID: 16604629.
- Newhauser WD, Titt U, Dexheimer D, Yan X, Nill S. Neutron shielding verification measurements and simulations for a 235-MeV Proton Therapy Center. Nucl Instr & Meth A476:80-84, 2002.
- Yan X, Newhauser WD, Titt U, Koehler AM. Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field. Nucl Instr & Meth A476:429-434, 2002.
- Dangendorf V, Schuhmacher H, Titt U, Tittelmeier K. Imaging of microscopic features of charged particle tracks in a low-pressure gas. Radiat Prot Dosimetry 99:353-354, 2002. PMID: 12194322.
- Titt U, Dangendorf V, Groβwendt V, Schuhmacher H. Development and Application of an Optical TPC for Charged Particle Track Structure Imaging in Microdosimetry. Nucl Instr & Meth A477:536-539, 2002.
- Titt U, Dangendorf V, Schuhmacher H. Digital imaging of charged particle track structures with a low pressure optical time projection chamber. Nucl Phys B (Pro Suppl) 78:444-448, 1999.
- Titt U, Breskin A, Checkhik R, Dangendorf V, Schmidt-Böecking H, Schuhmacher H. A time projection chamber with optical read out for charged particle track structure imaging. Nucl Instr & Meth A416:85-89, 1998.
- Titt U, Breskin A, Chechik R, Dangendorf V, Groβwendt B, Schuhmacher H. Concept of a neutron dosimeter based on a recoil particle track chamber. Radiat Prot Dosim 70:219-224, 1997.
Manuals, Teaching Aids, Other Teaching Publications
- Newhauser WD, Nill S, Titt U, Yan X, Smith AR. Neutron Area Monitoring for the Northeast Proton Therapy Center at the Massachusetts General Hospital. Northeast Proton Therapy Center Report NPTC-HD-102, 2000.
- Newhauser WD, Titt U, Dexheimer D, Yan X, Nill S. Neutron shielding verification measurements and simulations for a 235-MeV proton therapy center. Northeast Proton Therapy Center Report Number NPTC-91, 2000.
- Newhauser WD, Yan X, Titt U. Measurements of the neutron dose equivalent rates outside the NPTC building at 100-MeV and 230-MeV proton beam energies. Northeast Proton Therapy Center Report NPTC-HD-107, 2000.
Abstracts
- Martinus D, Flint D, Bright S, Titt u. Estimation of Uncertainties in the Distal Edge of Proton Beams Introduced by Inherent Variations in the Thickness of Plates Used to Perform Radiobiology Experiments, AAPM 2022, Washington, DC, 2022.
- Titt U, Wang L, Yang M, Wang X, Iga K, Sahoo N, Zhu X, Koong A, Lin S, Frank S, Mohan R. Designing Customized In-Vitro Experimental Setups for Proton FLASH Preclinical Studies, AAPM 2022, Washington, DC, 2022.
- Wang Q, Poenisch F, Titt U, Mohan R, Yepes P. Implementaion of a Track-Repeating Fast Monte Carlo Method for the MD Anderson Proton Therapy Center II, AAPM 2022, Washington, DC, 2022.
- He Y, Adair A, Cazoulat G, Yepes P, Titt U, Wu R, Mirkovic D, Balter P, Pollard-Larkin J, Cardenas C, Liao Z, Mohan R, Brock C. Modelling Variable Proton Relative Biological Effectiveness (RBE) using Voxel-Level Image Density Change for Non-Small Cell Lung Cancer (NSCLC) Patients Treated with Passive Scattering Proton Therapy (PSPT) or Intensity Modulated Photon Therapy (IMRT), ASTRO 2022, San Antonio, TX, 2022.
- Wang L, Yang M, Hang Q, Wang X, Titt U, Zhang Y, Heldring J, Sahoo N, Zhu XR, Frank SJ. Effect of FLASH versus Non-FLASH proton radiation on mice with head and neck cancer, PTCOG 60, 2022, Miami FL, 2022.
- Wang L, Yang M, Hang Q, Wang X, Titt U, Zhang Y, Heldring J, Sahoo N, Zhu XR, Frank SJ. Single and fractionated FLASH versus Non-FLASH proton radiation on mice with head and neck cancer, Radiation Research Society, 2022 Annual Meeting, Waikoloa Village, Hawaii, 2022.
- Titt U, Yang M, Wang X, Lin S. Zhu X, Iga K, Sahoo N, Koong A. Zhang X, Mohan R. Optimizing Design And commissioning of a Synchrotron Proton Beamline for FLASH Preclinical experiments, PTCOG 59, 2021 Online, 2021.
- Titt U, Grosshans D, Sahoo N, Zhu X, Mohan R,. Monte Carlo Evaluation of Neutron Dose Equivalent to Patients Treated with Vertex Beams in IMPT and PSPT, PTCOG 59, Online AAPM Virtual, 2021, 2021.
- Johnson D, Titt U, Yang M, Wang X, Fujimoto T, Fredette N, Lin S, Zhu R, Iga K, Sahoo N, Koong A, Zhang Z, Mohan R, Taniguchi C, Schuler E. Feasibility of a synchrotron-based proton FLASH irradiation platform for preclinical studies, Radiation Research Society's annual meeting, 2021, 2021.
- Adair A, Wang Q, Yepes P , Lin S , Aldehaim M , Titt U , Mirkovic D , Mohan R. Examining the Influence of Variable RBE Models On Passive Scattering Proton Therapy Esophageal Cancer Patients by Means of the Fast Dose Calculator at The University of Texas MD Anderson Cancer Center, AAPM 2019 San Antonio, Texas, 2019.
- Peeler C , Titt U , Mohan R , Liao Z , Mirkovic D. Tumor Control Probability for Non-Small Cell Lung Cancer Treated with Proton Therapy: Constant Versus Variable RBE-Weighted Dose, AAPM San Antonio, Texas, 2019.
- Titt U, Mirkovic D , Yepes P , Wang Q , Grosshans D , Bangert M , Wieser H , Mohan R. Detailed Evaluation of Properties of Protons, Helium, and Carbon Ions for Application in a Pediatric Ion Therapy Center, AAPM 2019 San Antonio, Texas, 2019.
- Titt U, Mirkovic D, Yepes P, Wang Q, Grosshans D, Bangert M, Mohan R. Preparing for Helium Therapy, PTCOG 2019, Manchester, UK, 2019.
- Mirkovic D, Titt U, Yang P, Liao Z, Mohan R. Analysis of recurrences in proton therapy of non-small cell lung cancer, PTCOG 2019, Manchester, UK, 2019.
- Bronk L, Kroger B, Ma D, Kerr M, Tran K, Teubner F, Patel D, Titt U, Sahoo N, Sulman E, Guan F, Mohan R, Grosshans D. MO-AB-KDBRA1-6: Mapping Biological Effects Along a Scanned 81.4 MeV Proton Beam: LET Modulation of the DNA Repair Response, AAPM 2018 Nashville, Tennessee, 2018.
- Yepes P, Adair A, Titt U, Mirkovic D, Wang Q, Poenosch F, Frank S, Liao Z, Mohan R. MO-E115-GePD-F4-3: Fixed- Versus Variable-RBE Computations for Intensity-Modulated Proton Therapy, AAPM 2018 Nashville, Tennessee, 2018.
- Newpower M, Patel D, Bronk L, Guan F, Grosshans D, Titt U, Mohan R. SU-F-KDBRA1-1: Applying a Saturation Correction to the Microdosimetric Kinetic Model Prediction for the Relative Biological Effectiveness of a Carbon Ion Beam, AAPM 2018 Nashville, Tennessee, 2018.
- Adair A, Wang Q, Yepes P, Titt U, Mirkovic D, Mohan R. SU-I-GPD-T-92: Patient Based Validation and Improvement of the Laboratory Based Calibration of the Fast Dose Calculator for Passive Scattering Proton Therapy, AAPM 2018 Nashville, Tennessee, 2018.
- Patel D, Poenisch F, Sahoo N, Zhu X, Gillin M, Janson M, Mohan R, Titt U. SU-I-GPD-T-102: Evaluation of a Pencil Beam Scanning Proton Dose Model for a Commercial Treatment Planning System, AAPM 2018 Nashville, Tennessee, 2018.
- Martin R, Williamson T, Yepes P, Colbert L, Poenisch F, Mirkovic D, Titt U, Mohan R, Beddar S, Taniguchi C, Sawakuchi G. SU-I-GPD-T-129: Hypofractionated Intensity Modulated Proton Therapy (IMPT) for Locally Advanced Pancreatic Cancer, AAPM 2018 Nashville, Tennessee, 2018.
- Martin R, WIlliamson T, Yepes P, Poenisch F, Melkun M, Titt U, Mirkovic D, Beddar S, Mohan R, Holliday E, Sawakuchi G. TU-C1000-GePD-F4-3: Intensity Modulated Proton Therapy (IMPT) for Anal Canal Cancer, AAPM 2018 Nashville, Tennessee, 2018.
- Mirkovic D, Yepes P, Titt U, Peeler C, Liao Z, Mohan R. TU-C1000-GePD-F7-5: Clinical Impact of Approximations in Analytical Dose Computations in Lung Patients Receiving Proton Therapy, AAPM 2018 Nashville, Tennessee, 2018.
- Yepes P, Mohan R, Liu A, Mirkovic D, Frank S, Titt U. Impact of Variable Relative Biological Effectiveness in Treatment Plans of a Large Cohort of Intensity Modulated Proton Therapy Head-And-Neck Patients, PTCOG 56 (2017) Japan, 2017.
- Peeler CR, Titt U, Grosshans DR, Liao Z, Mohan R, Mirkovic D. SU-F-FS1-1: Analysis of Differences in Tumor Control Probability Calculated From Monte Carlo and Treatment Planning System Dose Distributions for Proton Therapy. Med Phys 44(6), 2017.
- Court, L, Niedzielski J, Titt U, Yang J, Mohan R, Mirkovic D, Stingo F, Gomez D, Liao Z, Martel M, Briere. SU-F-FS1-2: Analysis of Normal Tissue Response in the Esophagus Between IMRT and Proton Therapy Using Imaging Biomarkers. Med Phys 44(6), 2017.
- Mirkovic D, Yang P, Belal Z, Titt U, Peeler CR, Liao Z, Mohan R. SU-I-GPD-T-97: Analysis of Recurrences in Lung Patients Treated with Protons. Med Phys 44(6), 2017.
- Bronk L, Guan F, Ma D, Wang Y, Kerr M, Patel D, Titt U, Vassiliev O, Lin S, Mohan R, Grosshans D. SU-K-108-8: High-Throughput Proton Irradiations Uncover a Differential DNA Damage Repair Response to P53 Depletion in Two Lung Cancer Cell Lines. Med Phys 44(6), 2017.
- Patel, D, Bronk L, Guan F, Peeler C, Brons S, Dokic I, Abhollahi A, Jakel O, Grosshans D, Mohan R, Titt U. MO-RAM-GePD-TT-2: Effect of Physics Based Monte Carlo Parameterization On the Accuracy of Transport Quantities. Med Phys 44(6), 2017.
- Titt, U, Yang J, Mirkovic D, Yepes P, Liu A, Peeler C, Mohan R. MO-RAM-GePD-T-4: Monte Carlo Cumulative 4D and 5D Proton Dose Distribution Computations and Their Comparison with Analytical Dose Computation Model Predictions for Lung Cancer Patients. Med Phys 44(6), 2017.
- Yepes P, Adair A, Liu A, Mirkovic D, Titt U, Wang Q, Mohan R. TU-C3-GePD-J(A)-3: Retrospective Dosimetric Analysis of Large Cohorts of Patients, the Tool and First Results. Med Phys 44(6), 2017.
- Adair A, Yepes P, Titt U, Mirkovic D, Mohan R. TU-L-GePD-TT-1: Commissioning of the Fast Dose Calculator for Passive Scattering Proton Therapy at the University of Texas MD Anderson Cancer Center. Med Phys 44(6), 2017.
- Guan F, Bronk L, Kerr M, Ma D, Wang Y, Wang X, Li Y, Vassiliev O, Patel D, Titt U, Lin S, Grosshans D, Mohan R. TH-AB-605-8: Investigation of the Spatial Ionization Density Dependence of the DNA Damage in a Lung Cancer Cell Line with Proton Irradiations. Med Phys 44(6), 2017.
- Kerr M, Bronk L, Guan F, Patel D, Li Y, Wang X, Sahoo N, Peeler C, Titt U, Mirkovic D, Grosshans D, Mohan R. Spatial Mapping of Scanned Proton Biologic Effect Using the High-Throughput Technique, Continued, AAPM 2016 Washington, DC. Med Phys 43(6):3888, 2016. PMID: 28046268.
- Guan F, Bronk L, Kerr M, Wang X, Li Y, Peeler C, Sahoo N, Patel D, Mirkovic M, Titt U, Grosshans D, Mohan R. Investigation of LET Spectral Dependence of the Biological Effects of Therapeutic Protons, AAPM 2016 Washington, DC. Med Phys 43(6):3843, 2016. PMID: 28047702.
- Titt U, Mirkovic D, Yepes P, Liu A, Peeler C, Randenyia S, Mohan R. 4D and 5D Proton Dose Evaluation with Monte Carlo, AAPM 2016 Washington, DC. Med Phys 43(6):3489-3490, 2016. PMID: 28046764.
- Mirkovic D, Titt U, Yepes P, Mohan R. Effects of Motion and Variable RBE in a Lung Patient Treated with Passively Scattered Protons, AAPM 2016 Washington, DC. Med Phys 43(6):3336, 2016. PMID: 28047696.
- Patel D, Bronk L, Guan F, Peeler C, Mirkovic D, Grosshans D, Jakel O, Abdollahi A, Mohan R, Titt U. Experimental Investigation of RBE for Lung Cancer Cell Lines as a Function of Dose and LET in Proton, Helium and Carbon Beams, AAPM 2016 Washington, DC. Med Phys 43(6):3843-3844, 2016. PMID: 28047053.
- Abolfath R, Bronk L, Helo Y, Schuemann J, Titt U, Grosshans D, Mohan R. A Nano-Dosimetric Kinetic Model for Variable Relative Biological Effectiveness of Proton and Ion Beams, AAPM 2016 Washington, DC. Med Phys 43(6):3842, 2016. PMID: 28047579.
- Yepes P, Titt U, Mirkovic D, Liu A, Frank S, Mohan R. Are the Approximations in Analytic Semi-Empirical Dose Calculation Algorithms for Intensity Modulated Proton Therapy for Complex Heterogeneities of Head and Neck Clinically Significant?, AAPM 2016 Washington DC. Med Phys 43(6):3496, 2016. PMID: 28048730.
- Peeler C, Mirkovic D, Titt U, Grosshans D, Mohan R. Voxel-Level Analysis of Adverse Treatment Response in Pediatric Patients Treated for Ependymoma with Passive Scattering Proton Therapy, AAPM 2016 Washington, DC. Med Phys 43(6):3828-3829, 2016. PMID: 28048899.
- Kim D, Titt U, Mirkovic D. Uptake Dose Response in Lung Correlates Linearly with Proton Therapy Dose, AAPM 2016 Washington, DC. Med Phys 43(6):3491-3492, 2016. PMID: 28048762.
- Titt U, Bronk L, Patel D, Guan F, Peeler C, Mohan R. In-vitro survival of H460 and H1437 cells as a function of dose and LET in proton, helium and carbon beams, PTCOG 55 (2016) Prague / Czech Republic, 2016.
- Taleei R, Peeler C, Guan F, Patel D, Titt U, Mirkovic D, Grosshans D, Mohan R. Modeling Biological Response to Proton Irradiation and Evaluating Its Potential Clinical Consequences. Med Phys 42(6):3461, 2015. PMID: 26128210.
- Mirkovic D, Peeler C, Grosshans D, Titt U, Taleei R, Mohan R. Modeling Relative Biological Effectiveness of Protons for Radiation Induced Brain Necrosis. Med Phys 42(6):3461, 2015. PMID: 26128212.
- Titt U, Suzuki K. Validation of the MCNPX Monte Carlo Model of the Ocular Beam Line at the Proton Therapy Center Houston. Med Phys 42(6):3520, 2015. PMID: 26128458.
- Peeler C, Taleei R, Guan F, Bronk L, Patel D, Titt U, Mirkovic D, Stewart R, Grosshans D, Mohan R. Relative Biological Effectiveness of Double-Strand Break Induction for Modeling Cell Survival in Pristine Proton Beams of Different Dose-Averaged Linear Energy Transfers. Med Phys 42(6):3529, 2015. PMID: 26128495.
- Guan F, Bronk L, Kerr M, Titt U, Wang X, Taleei R, Peeler C, Patel D, Mirkovic D, Grosshans D, Mohan R. Quantifying the Biological Effects of Therapeutic Protons by LET Spectrum Analysis. Med Phys 42(6):3616, 2015. PMID: 26128964.
- Titt U, Bronk L, Patel D, Guan F, Taleei R, Grosshans D, Brons S, Bangert M, Jakel O, Mohan R. High throughput, high accuracy cell survival experiments with proton, helium, and carbon beams, PTCOG 54 (2015) San Diego, California, 2015.
- Taleei R, Peeler C, Guan F, Patel D, Titt U, Mirkovic D, Stewart R, Grosshans D, Mohan R. Modeling Biological Response to Proton Irradiation and Evaluating Its Potential Clinical Consequences, AAPM 2015 Anaheim, California. Med Phys 42:3461, 2015.
- Peeler C, Taleei R, Guan F, Bronk L, Patel D, Titt U, Mirkovic D, Stewart R, Grosshans D, Mohan R. Relative Biological Effectiveness of Double-Strand Break Induction for Modeling Cell Survival in Pristine Proton Beams of Different Dose-Averaged Linear Energy Transfers, AAPM 2015, Anaheim, California. Med Phys 42:3529, 2015.
- Guan F, Bronk L, Kerr, M, Titt U, Wang X, Taleei R, Peeler C, Patel D, Mirkovic D, Grosshans D, Mohan R. Quantifying the Biological Effects of Therapeutic Protons by LET Spectrum Analysis, AAPM 2015 Anaheim, California. Med Phys 42:3616, 2015.
- Guan F, Titt U, Patel D, Bronk L, Taleei R, Peeler C, Mirkovic D, Grosshans D, Jakel O, Mohan R. Experimental Design for High-Throughput In-Vitro RBE Measurements Using Protons, Helium and Carbon Ions, AAPM 2015 Anaheim, California. Med Phys, 2015.
- Titt U, Suzuki K. Validation of the MCNPX Monte Carlo Model of the Ocular Beam Line at the Proton Therapy Center Houston, AAPM 2015 Anaheim, California. Med Phys, 2015.
- Mirkovic D, Peeler C, Grosshans D, Titt U, Taleei R, Mohan R. Modeling Relative Biological Effectiveness of Protons for Radiation Induced Brain Necrosis, AAPM 2015 Anaheim, California. Med Phys, 2015.
- Cao W, *Zaghian M, Randeniya K, Lim G, Titt U, Mohan R. An Investigation of Including Variable Relative Biological Effectiveness in Intensity Modulated Proton Therapy Planning Optimization for Head and Neck Cancer Patients, AAPM 2015 Anaheim, California. Med Phys 42:3356, 2015.
- Titt U, Mirkovic D, Liu AY, Anand A, Perles LA, Ciangaru G, Mohan R. Commissioning of the MC² Monte Carlo Dose Computation Engine, PTCOG-53 June 2014 Shanghai, China, 2014.
- Titt U, Mirkovic D, Liu AY, Anand A, Perles LA, Ciangaru G, Mohan R. Commissioning of the MC² Monte Carlo Dose Computation Engine, AAPM 2014 Austin, Texas. Med Phys 41:362, 2014.
- Guan F, Titt U, Taleei R, Bangert M, Mirkovic D, Zhu XR, Carlson D, Grosshans D, Mohan R. Monte Carlo Analysis of the Dose Contributions from Primary and Secondary Particles in Light-Ion Therapy, PTCOG-53 June 2014, Shanghai, China, 2014.
- Peeler C, Guan F, Bronk L, Grosshans D, Mirkovic D, Titt U, Mohan R. Application of the Repair-Misrepair-Fixation RBE Model to Describe the Results of High Resolution Proton Irradiation Cell Survival Experiments, AAPM 2014 Austin, Texas. Med Phys 41:232, 2014.
- Randeniya S, Mirkovic D, Titt U, Guan F, Mohan R. Importance of Energy Dependent Protons per MU Calibration Factors in IMPT Dose Calculations Using Monte Carlo Technique, AAPM 2014 Austin, Texas. Med Phys 41:339, 2014.
- Bronk L, Guan F, Kerr M, Dingh J, Titt U, Mirkovic D, Lin S, Mohan R. High-Throughput Mapping of Proton Biologic Effect, AAPM 2014 Austin, Texas. Med Phys 41:505, 2014.
- Taleei R, Titt U, Peeler C, Mirkovic D, Grosshans D, Mohan R. Modeling Physics Properties and Biologic Effects Induced by Protons, AAPM 2014 Austin, Texas. Med Phys 41:534, 2014.
- Guan F, Bronk L, Kerr M, Titt U, Taleei R, Mirkovic D, Zhu X, Grosshans D, Mohan R. The Effect of Particle Tracking Step Size Limit on Monte Carlo Computed LET Spectrum of Therapeutic Proton Beams, AAPM 2014 Austin, Texas. Med Phys 41:534, 2014.
- Mirkovic D, Yepes P, Titt U, Mohan R. Fast Four Dimensional Monte Carlo Dose Computations for Proton Therapy of Lung Cancer, AAPM 2014 Austin, Texas. Med Phys 41:535, 2014.
- Guan F, Mohan R, Dihn J, Kerr M, Perles L, Mirkovic D, Titt U, Zhu X, Gillin M, Meyn R, Lin S, Grosshans D. Experimental Design and Preliminary Results for High-Resolution and High-Throughput In-Vitro Measurements of Proton RBE, PTCOG-52 June 2013 Essen, Germany. Med Phys 40:552, 2013.
- Poenisch F, Kerr M, Zhu XR, Sahoo N, Dhanesar S, Titt U, Suzuki K, Mohan R, Gillin MT. Measurement of the Effect of Apertures in Proton Scanning Beam, PTCOG-52 June 2013 Essen, Germany, 2013.
- Titt U, Mirkovic D, Liu AY, Mohan R,. Automated Monte Carlo Simulations of Proton Treatment Plans, PTCOG-52 Essen Germany, June 2013, 2013.
- Perles LA, Titt U, Mirkovic D, Mohan R. Modeling the Cell Inactivation Process for High LET Particles by Using the Law of Mass Action, AAPM 2013 Indianapolis, Indiana. Med Phys 40:272, 2013.
- Titt U, Liu AY, Mirkovic D. Runtime Optimization for the Automatic Monte Carlo Dose Computation System MC2, AAPM 2013 Indianapolis, Indiana. Med Phys 40:326, 2013.
- Titt U, Mirkovic D. Mohan R. Three-Dimensional Energy Fluence Estimates for Future Treatment Planning Systems, AAPM 2013 Indianapolis, Indiana. Med Phys 40:88, 2013.
- Guan F, Titt U, Bangert M, Mohan R. In Search of the Optimum Ion for Radiotherapy, AAPM 2013, Indianapolis, Indiana. Med Phys 40:320, 2013.
- Titt U, Guan F, Mirkovic D, Mohan R,. On the Out-of-Field-Doses Caused by Secondary Particles from Light Ion Beams in Charged Particle Therapy, AAPM 2013 Indianapolis, Indiana. Med Phys 40:328, 2013.
- Howell R, Kry S, Titt U. Project Based Learning - Expanding Course Content with a Broad-Scope Project, AAPM 2013 Indianapolis, Indiana. Med Phys 40:413, 2013.
- Mirkovic D, Titt U, Peeler C, Perles L, Liao Z, Mohan R. Variable RBE and Incidence of Radiation Pneumonitis in Lung Patients Treated with Proton Therapy, AAPM 2013 Indianapolis, Indiana. Med Phys 40:455, 2013.
- Cho J, Ibbott G, Gillin M, Gonzales-Iepera, Titt U, Mawlawi O. Proton Beam Range Verification Using Proton Activated Fiducials and Off-Site PET, AAPM 2013 Indianapolis, Indiana. Med Phys 40:503, 2013.
- Peeler C, Mirkovic D, Perles L, Titt U, Grosshans D, Mohan R. Comparison of Results for RBE-Weighted Dose from Two RBE Models for Proton Therapy Plans, AAPM 2013 Indianapolis, Indiana. Med Phys 40:552, 2013.
- Guan F, Mohan R, Dinh J, Kerr M, Perles L, Mirkovic D, Titt U, Zhu X, Gillin M, Meyn R, Lin S, Grosshans D. Experimental Design and Preliminary Results for High-Resolution and High-Throughput In-Vitro Measurements of Proton RBE, AAPM 2013 Indianapolis, Indiana. Med Phys 40:552, 2013.
- Zhu XR, Poenisch F, Lii M, Sawakuchi GO, Titt U, Bues M, Song X, Zhang X, Li Y, Giangaru G, Li H, Tayler MB, Suzuki K, Mohan R, Gillin MT and Sahoo N. Commissioning dose computation models for spot scanning proton beams in water for a commercially available treatment planning system, AAPM 2013 Indianapolis, Indiana. Med Phys 40:041723, 2013.
- Titt U, Mirkovic D, Liu A, Mohan R. SU-E-T-435: Automatic Monte Carlo Dose Calculations of Proton Treatment Plans. Med Phys 39(6Part16):3805, 2012. PMID: 28517181.
- Bangert M, Titt U, Ziegenhein P, Mohan R, Oelfke U. SU-E-T-396: Beam Angle Optimization for IMPT Comparing Gantries and Fixed Beam Lines. Med Phys 39(6Part16):3795, 2012. PMID: 28517218.
- Titt U, Mirkovic D, Perles L, Sell M, Peeler C, Liu A, Mohan R. SU-E-T-474: Monte Carlo Phase Space Production to Model Magnetically Scanned Proton Beams for IMPT. Med Phys 39(6Part17):3814, 2012. PMID: 28517438.
- Mirkovic D, Titt U, Mohan R. SU-E-T-484: Potential Clinical Impact of Dosimetric Uncertainties in Proton Therapy. Med Phys 39(6Part17):3816, 2012. PMID: 28517453.
- Sell M, Titt U, Perles L, Mirkovic D, Mohan R, Bangert M, Oelfke U. WE-E-BRB-02: Evaluation of Analytical Proton Dose Predictions with a Lung-Like Plastic Phantom. Med Phys 39(6Part27):3956, 2012. PMID: 28520021.
- Titt U, Mirkovic D, Perles L, Peeler C, Liu A, Mohan R. Monto Carlo Phase Space Production to Model Magnetically Scanned Proton Beams for IMPT, AAPM 2012 Charlotte, North Carolina. Med Phys 39:3814, 2012.
- Peeler C, Mirkovic C, Grosshans D, Titt U Mohan R. Correlating Areas of Radiation Toxicity with Relative Biological Effectiveness-Weighted Dose Distributions in Proton Radiotherapy, AAPM 2012 Charlotte, North Carolina. Med Phys 39(3994), 2012.
- Perles L, Mirkovic D, Annand A, Titt U, Mohan R. Dose Response of EBT2 Film Modeled as a Biomelecular Reaction, AAPM 2012, Charlotte, North Carolina. Med Phys 39:4009, 2012.
- Perles LA, Mirkovic D, Sawakuchi GO, Titt U. Monte Carlo Investigation of Rebinning Material Density Distributions of Lung Parenchyma Phantoms in Proton Therapy (2010 16th Biennial Topical Meeting of the American-Nuclear Society (ANS) and Radiation Protection and Shielding Division (RPSD), Las Vegas, Nevada. Nucl Technol 175(1 (S1)):22-26, 2011.
- Mirkovic D, Titt U, Fang C, Cox J, Mohan R. Monte Carlo Investigation of Dosimetric Uncertainties in Proton Therapy of Lung Cancer, 2011.
- Titt U, Mirkovic D, Ciangaru G, Mohan R. A novel tool for patient specific quality assurance, 2011.
- Mohan R, Mirkovic D, Titt U, Song X, Li H, Zhu X, Gillin M. Experimental Assessment of the Accuracy of a Semi-Empirical Model and a Monte Carlo System for Proton Dose Calculations for Highly Inhomogeneous Media, AAPM 2011, Vancouver, Canada. Med Phys 38:3648, 2011.
- Randeniya S, Mirkovic D, Kry S, Titt U, Newhauser W, Howell R. Patient Specific Out-of-Field Dose Calculation Tool for 6MV and 18MV: Development and Validation, AAPM 2011 Vancouver, Canada. Med Phys 38:3736, 2011.
- Perles L, Ibbott G, Blatnica A, Mirkovic D, Titt U, Gillin M, Mohan R. 3D Proton Dose Distributions in an Anthropomoric Lung Phantom, Comparing Monte Carlo, Film,and TLD Measurements, AAPM 2011, Vancouver, Canada. Med Phys 38:3780, 2011.
- Mirkovic D, Titt U, Mohan R. Accuracy of Patient Dose Calculation in Proton Therapy of Lung Cancer: A Comparison of Monte Carlo and Pencil Beam Computations, AAPM 2011 Vancouver, Canada. Med Phys 38:3642, 2011.
- Cho J, Mawlawi O, Gillin M, Titt U, Gonzalez-Lepera C and Ibbott G. Proton Beam Range Verification with PET: Comparison of 0-18, 0-16 and C-12 Activation, AAPM 2011 Vancouver, Canada. Med Phys 38:3831, 2011.
- Titt U, Mirkovic D, Anand A, Perles L, Sawakuchi G and Mohan R. On the Dependence of Scanned Proton Beam Dose Output Factors on the Field Size and the Accuracy of the Lateral Dose Profiles, AAPM 2011 Vancouver, Canada. Med Phys 38:3382, 2011.
- Anand A, Sahoo N, Zhu X, Titt U, Sawakuchi G, Li Y, Poenisch F, Amos R, Suzuki K, Ciangaru G, Mohan R and Gillin M. Scanned Proton Pencil Beam's Lateral Profile Library to Describe the Spot Dose Characteristics, AAPM 2011 Vancouver, Canada. Med Phys 38:3855, 2011.
- Yepes PP, Brannan T, Huang J, Mirkovic D, Newhauser WD, Taddei PJ, Titt U. Application of a fast proton dose calculation algorithm to a thorax geometry (2009 11th Neutron and Ion Dosimetry Symposium, Cape Town, South Africa). Radiat Meas 45(10 (S1)):1367-1368, 2010.
- Titt U, Mirkovic D, Sawakuchi GO, Perles LA, Newhauser WD, Taddei PJ, Mohan R. Spot size manipulation for magnetically scanned proton beams, 2010.
- Sawakuchi GO, Sahoo N, Gasparian GPR, Rodrigues MG, Archambault L, Titt U, Yukihara EG. Determination of the average LET of therapeutic proton beams using AL2 O3 C optically stimulated luminescence (OSL) detectors. Phys Med Biol 55:4963-4976, 2010.
- Mirkovic D, Titt U, Sawakuchi G, and Mohan R. Biological Effects of Variable RBE in Different Proton Therapy Delivery Modalities, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:3365, 2010.
- Bednarz B, Mirkovic D, Titt U and Paganetti H. A Joint Research Investigation Comparing MCNPX and Geant4 Monte Carlo Codes to Reduce the Range Uncertainties in Proton Therapy, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:3286, 2010.
- Perles L, Sawakuchi G, Mirkovic D, Mohan R and Titt U. Monte Carlo Investigation and Measurements of Distal Edge Degradation in Lung Phantoms with Therapeutic Proton Beams, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:3145, 2010.
- Melancon A, Lee A, Kudchadker R, Titt U, Beddar S, Zhu X and Dong L. Range Adaptive Proton Therapy for Prostate Cancer, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:3332, 2010.
- Titt U, Mirkovic D, Sawakuchi G, Perles L, Newhauser W, Taddei P and Mohan R. Adjustment of Lateral and Longitudinal Size of Scanned Proton-Beam Spots Using a Pre-Absorber, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:3353, 2010.
- Randeniya S, Mirkovic D, Kry S, Titt U, Newhauser W and Howell R. Automated Photon Monte Carlo Linear Accelerator Model for Calculating In-Field and Out-Of-Field Dose, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:3281, 2010.
- Sawakuchi G, Zhu X, Poenisch F, Suzuki K, Ciangaru G, Titt U, Anand A, Mohan R, Gillin M, Sahoo N. Experimental Characterization of the Low-Dose Envelope of Spot Scanning Proton Beams, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:3426, 2010.
- Gillin MT, Sahoo N, Bues M, Ciangaru G, Sawakuchi G, Poenisch F, Arjomandy B, Martin C, Titt U, Suzuki K, Smith AR and Zhu XR. Commissioning of the discrete spot scanning proton beam delivery system at the University of Texas M.D. Anderson Cancer Center, Proton Therapy Center, Houston, AAPM 2010 Philadelphia, Pennsylvania. Med Phys 37:154, 2010.
- Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng YS, Titt U, Woo SA, Newhauser WD. Reducing Stray Radiation Dose for a Pediatric Patient Receiving Proton Craniospinal Irradiation - 2008 11th International Conference on Radiation Shielding / 15th Topical Meeting of the Radiation Protection and Shielding Division, Pine Mount, Georgia. Nucl Technol 168(1):108-112, 2009.
- Fontenot J, Bloch C, Followill D, Titt U, Zhang M, Newhauser W. Estimate of the uncertainty in relative secondary cancer risk calculations following proton therapy and intensity modulated x-ray therapy. Med Phys 36:2723, 2009.
- Titt U. Results of a Monte Carlo study of a flattening filter free (FFF) clinac, 2009.
- Bues M and Titt U. Proton therapy, the Houston experience, 2009.
- Titt U, Paganetti H and Mohan R. Comparing Geant4 and MCNPX for Joint Research to Minimize Uncertainties in Proton Therapy, AAPM 2009 Anaheim, California. Med Phys 36:2624, 2009.
- Mirkovic D, Titt U, Sawakuchi G, Zhang X, Li Y and Mohan R. Monte Carlo Computation of the Effective Dose in Scanning Beam Proton Therapy, AAPM 2009 Anaheim, California. Med Phys 36:2612, 2009.
- Melancon A, Archambault L, Lee A, Kudchadker R, Zhang L, Beddar S, Titt U and Dong L. In Vivo Detection of the Anterior Rectal Wall Using a Scintillation Fluid-Filled Rectal Balloon for Prostate Cancer Radiotherapy, AAPM 2009 Anaheim, California. Med Phys 36:2431, 2009.
- Giebeler A, Zhu X, Starkschall G, Balter P, Titt U, Tucker S and Newhauser W. Estimation of Uncertainty for the Patient and Compensator Scatter Correction Factor in Proton Therapy D/MU Calculations, AAPM 2009 Anaheim, California. Med Phys 36:2668, 2009.
- Zhu X, Sahoo N, Sawakuchi G, Lii M, Ciangaru G, Bues M, Pan X, Zhang X, Ding X, Titt U, Arjomandy B, Suzuki K, Mohan R and Gillin M. Configuration and Validation of a Double Gaussian Dose Model for Scanning Proton Beams, AAPM 2009 Anaheim, California. Med Phys 36:2667, 2009.
- Titt U, Zhang X, Mirkovic D, Sawakuchi G, Mohan R. Monte Carlo study of distal edge degradation in proton therapy due to heterogeneities. Med Phys 35:2798, 2008.
- Titt U, Zheng Y, Vassiliev O, Newhauser W. Monte Carlo investigation of collimator scatter in proton-therapy beams using the passive scattering technique. Med Phys 35:2797, 2008.
- Sawakuchi G, Titt U, Mohan R. The contribution of nuclear products of the lateral profile of the pencil scanning proton beams from the MD Anderson Proton Therapy Center Houston nozzle: the halo effect. Med Phys 35:2797, 2008.
- Ding X, Sahoo N, Zhu X, Yang J, Arjomandy B, Lii M, Titt U, Mohan R, Smith A, Gillin M. Validation study of the GEANT 4 Monte-Carlo simulation of the Proton Dose distribution from passively scattered proton beam nozzles at the Proton Therapy Center Houston. Med Phys 35:2799, 2008.
- Taddei P, Mirkovic D, Fontenot J, Giebeler A, Zheng Y, Titt U, Woo S, Newhauser W. Reducing stray radiation dose for a pediatric patient receiving craniospinal irradiation with protons. Med Phys 35:2845, 2008.
- Melancon A, Archambault L, Lee A, Kudchadker, R, Zhang L, Beddar S, Titt U, Dong L. In vivo detection of the anterior rectal wall using a scintillation fluid-filled rectal balloon for prostate cancer radiotherapy. Med Phys 36:2313, 2008.
- Mirkovic D, Titt U, Sawakuchi G, Zhang X, Li Y, Mohan R. Monte Carlo computation of the effective dose in scanning beam proton therapy. Med Phys 36:2613, 2008.
- Sawakuchi G, Titt U, Ciangaru G, Mirkovic D, Zhu X, Mohan R. The causes of the lateral envelope of low doses in scanning proton beamlets. Med Phys 36:2620, 2008.
- Giebeler A, Zhu X, Starkschall G, Balter P, Titt U, Tucker S, Newhauser W. Estimation of uncertainty for the patient and compensator scatter correction factor in proton therapy D/MU calculations. Med Phys 36:2668, 2008.
- Sawakuchi G, Titt U, Mirkovic D, Zhu X, Sahoo N, Bues M, Ciangaru G, Poenisch F, Suzuki K, Arjomandy B, Gillin M, Mohan R. Validation of an MCNPX Monte Carlo model of a discrete-spot scanning beam nozzle and evaluation of the beamlet lateral envelope dose. Med Phys 36:2782, 2008.
- Sawakuchi G and Titt U. Monte Carlo Study of Proton Beam Energy Spectra Downstream of Density Heterogeneities and the Influence of Multiple Coulomb and Nuclear Scatterings on the Bragg Peak Distal Falloff. Med Phys 35:2954, 2008.
- Kry S, Vassiliev O, Titt U and Mohan R. Dose Outside the Treatment Volume Following Removal of the Flattening Filter, AAPM 2008 Houston, Texas. Med Phys 35:2983, 2008.
- Kry SF, Howell RM, Titt U, Salehpour M, Mohan R and Vassiliev ON. Energy spectra, sources, and shielding considerations for neutrons generated by a flattening filter-free Clinac, AAPM 2008 Houston, Texas. Med Phys 35:1906, 2008.
- Smith A, Sahoo N, Ciangaru G, Polf J, Titt U. Concepts in proton therapy treatment planning, delivery and QA:19, 2007.
- Newhauser WD, Fontenot JD, Zheng Y, Taddei P, Mirkovic D, Titt U, Zhu X, Sahoo N, Schaffner B, Langenegger A, Koch NC, Zhang X, Mohan R. A Monte Carlo based dose engine for proton radiotherapy treatment planning, AAPM 2007 Minneapolis, MN, USA. Med Phys 34:2406, 2007.
- Vassiliev ON, Titt U, Mohan R. Low dose RBE of therapeutic proton beams, AAPM 2007 Minneapolis, MN, USA. Med Phys 34:2467, 2007.
- Taddei P, Fontenot JD, Zheng Y, Mirkovic D, Titt U, Newhauser WD. Monte Carlo investigation of local shielding to reduce stray radiation doses to patients receiving proton therapy, AAPM 2007 Minneapolis, MN, USA. Med Phys 34:2471-2472, 2007.
- Vassiliev ON, Kry SF, Chang J, Balter PA, Titt U, Mohan R. Stereotactic radiotherapy for lung cancer using flattening filter free accelerator, AAPM 2007 Minneapolis MN, USA. Med Phys 34:2491, 2007.
- Titt U, Sahoo N, Zhu X, Ding X, Zheng Y, Gillin MT, Mohan R. Validation of the Monte Carlo model of the passive scattering nozzles at the Proton Therapy Center Houston, AAPM 2007 Minneapolis MN, USA. Med Phys 34:2503, 2007.
- Mohan R, Zhang X, Titt U, Zhu X, Dong L. Reducing uncertainties in proton therapy achieving what you see is what you get, AAPM 2007 Minneapolis MN, USA. Med Phys 34:2552, 2007.
- Kry S, Salehpour M, Titt U, Stovall M, White R and Followill D. A Monte Carlo Study of the Out-Of-Field Dose From IMRT, AAPM 2007 Minneapolis, Minnesota. Med Phys 34:2406, 2007.
- Vassiliev ON, Beddar AS, Krishnan, Briere TM, Gillin MT, Mohan R, Titt U. Treatment planning study of liver cancer treatments with a flattening filter free linear accelerator, AAPM 2006 Orlando FL, USA. Med Phys 33:2064, 2006.
- Ponisch F, Titt U, Vassiliev ON, Kry SF, Mohan R. Properties of unflattened photon beams shaped by a multi leaf collimator, AAPM Orlando FL, USA. Med Phys 33:2131, 2006.
- Newhauser WD, Zheng Y, Fontenot JD, Koch NC, Polf JC, Schaffner B, Titt U. Implementation of the varian eclipse system for proton therapy treatment planning, AAPM 2006 Orlando FL, USA. Med Phys 33:2284, 2006.
- Titt U, Zheng Y, Zhu XR, Mohan R, Newhauser WD,. Verification of a proton treatment-planning pencil-beam dose algorithm with Monte Carlo, AAPM 2006 Orlando FL, USA. Med Phys 33:2149, 2006.
- Wareing TA, Failla G, Vassiliev ON, Barnett A, McGhee JM, Titt U, Horton Jr. JL, Mourtada F. Performance assessment of a deterministic method incorporating coupled photon-election transport for photon beam dose calculations on acquired CT, AAPM 2006 Orlando FL, USA. Med Phys 33:2292, 2006.
- Titt U, Vassiliev ON, Poenisch F, Kry SF, Mohan R. Monte Carlo study of backscatter in a flattening filter free clinical accelerator, AAPM 2006 Orlando FL, USA. Med Phys 33:3270, 2006.
- Sadagopan R, Titt U, Tailor R. Dose variation within lung tumor and in its fingerlike extension as a function of incident photon angle, AAPM 2006 Orlando FL, USA. Med Phys 33:2284, 2006.
- Vassiliev ON, Titt U, Gillin MT, Mohan R. Dosimetric properties of 8 and 10 MV photon beams from a flattening filter free clinical accelerator, AAPM 2006 Orlando FL, USA. Med Phys 33:2294, 2006.
- Titt U, Vassiliev ON, Ponisch F, Dong L, Liu H and Mohan R. A flattening filter free photon treatment concept evaluation with Monte Carlo, AAPM 2006 Orlando, Florida. Med Phys 33:1595, 2006.
- Kry S, Vassiliev O, Kuban D, Poenisch F, Salehpour M, Gillin M, Mohan R and Titt U. Treatment Planning Study of Prostate Cancer IMRT with a Flattening Filter Free Accelerator, AAPM 2006 Orlando, Florida. Med Phys 33:2146, 2006.
- Titt U, Vassiliev ON, Ponisch F, Kry SF, Gillin MT, Mohan R. Flattening filter free IMRT, first experimental results, AAPM 2005 Seattle, WA, USA. Med Phys 32:2144-2146, 2005.
- Kry SF, Titt U Salehpour M, Ponisch F, Followill D, Vassiliev ON, Mohan R. A Monte Carlo simulation of out-of-field radiation from an 18-MV beam, AAPM 2005 Seattle WA, USA. Med Phys 32:1889, 2005.
- Kry SF, Titt U, Ponisch F, Vassiliev ON, Salehpour M, Gillin M, Mohan R. A reduction in neutron production through the use of a flattening-filter-free accelerator, AAPM Seattle WA, USA. Med Phys 32:2146, 2005.
- Vassiliev ON, Titt U, Ponisch F, Kry SF, Gillin MT, Mohan R. Dosimetric properties of photon beams from a flattening filter free clinical accelerator, AAPM 2005 Seattle, WA USA. Med Phys 32:1896, 2005.
- Poenisch F, Titt U, Vassiliev ON, Kry SF, Gillin MT, Mohan R. Validation of a highly detailed multi leaf collimator model by comparing Monte Carlo simulations to measurements, AAPM 2005 Seattle, WA, USA. Med Phys 32:2014, 2005.
- Newhauser WD, Koch N, Hummel S, Ziegler M, Titt U. Monte Carlo simulations of a nozzle for the treatment of ocular tumors with high-energy proton beams, AAPM Seattle, WA, USA. Med Phys 32:2165, 2005.
- Kry S, Titt U, Poenisch F, Followill D, Vassiliev O, Mohan R. A Monte Carlo Simulation of Out-Of-Field Radiation From an 18-MV Beam, AAPM 2005 Seattle, Washington. Med Phys 32:1889, 2005.
- Titt U, Vassiliev ON, Dong L, Liu H, Mohan R. A flattening filter free photon treatment concept evaluation with Monte Carlo, AAPM 2004 Pittsburgh USA. Med Phys 31:1811, 2004.
- Titt U, Ponisch F, Kry SF, Dong L, Stovall MS. Exploring stray radiation dose to photon radiation therapy patients with MCNPX, AAPM Pittsburgh USA. Med Phys 31:1887, 2004.
- Fontenot J, Titt U, Newhauser WD. Design tools for proton therapy nozzles based on the double-scattering technique, AAPM Pittsburgh USA. Med Phys 31:1723, 2004.
Book Chapters
- Mohan R, Titt U, and Guan F. Chapter 2, Particle Therapy in the Third Millennium: Current Status and Future Outlook. In: Particle Radiotherapy - Emerging Technology for Treatment of Cancer. Springer, 2016.
Grant & Contract Support
Title: | Deterministic Radiotherapy Dose Evaluation |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Distal Edge Degradation in Proton Therapy and its repair |
Funding Source: | Varian Master Research Agreement (Project 9) |
Role: | Principal Investigator |
Title: | Conventional & Intensity-Modulated Radiation Therapy (IMRT) System Based on a Flattening-Filter Free (FFF) Linear Accelerator |
Funding Source: | Varian Master Research Agreement (Project 3) |
Role: | Principal Investigator |
Title: | Investigation of Dosimetric and Late Effects for Patients Receiving Proton Beam Therapy |
Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
Role: | Co-Investigator |
Title: | Monte Carlo Neutron Shielding of Proton Therapy Facilities |
Funding Source: | Bechtel Infrastructure Corporation |
Role: | Principal Investigator |
Title: | Intensity Modulated Particle Therapy |
Funding Source: | Sister Institution Network Fund |
Role: | Co-Investigator |
Title: | Optimizing Proton Therapy - Project 3: Reducing Range Uncertainties in Proton Radiation Therapy |
Funding Source: | NIH/NCI |
Role: | Project Leader |
Title: | Moving proton therapy towards its full potential by using fast Monte Carlo techniques |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Investigator |
Title: | The future of particle therapy:Physics and biology of light ions |
Funding Source: | UTMDACC - The Center for Radiation Oncology Research |
Role: | Principal Investigator |
Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis of Proton Therapy: Core B - Clinical & Research Support at MDACC |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis of Proton Therapy: Project 3 - Assessing accuracy of proton therapy and understanding the impact of physical and biophysical factors on its outcomes |
Funding Source: | NIH/NCI |
Role: | Project Leader |
Title: | Understanding Biological and Physical Factors Affecting Response to Proton Therapy to Improve its Clinical Effectiveness |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Investigator |
Title: | Advancing Linear Energy Transfer Models for Biologically Optimized Proton Therapy |
Funding Source: | MDACC-IRG |
Role: | Co-Investigator |
Title: | Mapping Proton RBE Variability Using Automated Biology and Monte Carlo Techniques |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | The future of particle therapy: Physics and biology of light ions |
Funding Source: | Sister Institution Network Fund Application |
Role: | Principal Investigator |
Title: | Optimizing Proton Therapy - Core B: Clinical and Computational Support |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Improving Survival Outcomes Harnessing the Biological, Immunologic and Physical Properties of Heavy Charged Particles |
Funding Source: | MDACC |
Role: | Core Director |
Title: | Pre-clinical studies of heavy ions and protons |
Funding Source: | Radiation Oncology Strategic Initiative (ROSI) |
Role: | Co-Investigator |
Title: | Investigating Patient, Tumor, and Treatment Factors Underlying Sensitivity of Cancers and Normal Tissues to Proton vs Photon Radiation: Core 1 Data Management and Computational Support Core |
Funding Source: | NIH/NCI |
Role: | Core Lead |
Title: | Radiosensitivity of Immune Cells as a Function of Dose, Linear Energy Transfer and Ion Species and its Impact on Incidence and Severity of Radiation Induced Immune System Suppression |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Investigating Patient, Tumor, and Treatment Factors Underlying Sensitivity of Cancers and Normal Tissues to Proton vs Photon Radiation: Project 1 Understanding normal tissue toxicity to identify patients most likely to benefit from proton therapy |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | The potential of proton FLASH radiotherapy to improve osteosarcoma outcomes |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |