Wei Ying Jen, BM BCh, FRCPath

Peer-Reviewed Articles

1. Jen, WY, Marvin-Peek, J, Kantarjian, HM, Alvarado, Y, Borthakur, G, Jabbour, EJ, Wierda, WG, Kadia, TM, Daver, N, DiNardo, C, Short, NJ, Jain, N, Ferrajoli, A, Kornblau, SM, Yilmaz, M, Ohanian, M, McCue, D, Burger, JA, Hammond, DE, Patel, K, Issa, GC, Pemmaraju, N, Sasaki, K, Maiti, A, Abbas, HA, Chien, KS, Takahashi, K, Haddad, FG, Bose, P, Masarova, L, Montalban Bravo, G, Swaminathan, M, Brandt, M, Pierce, S, Garcia-Manero, G, Ravandi, F. Long-term follow-up of a phase 2 study of all-trans retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin in acute promyelocytic leukemia. Cancer 131(1), 2025. e-Pub 2025. PMID: 39584789.
2. Sahib, NM, Mohamed, JS, Rashid, MA, Jayalakshmi, Lin, YC, Chee, YL, Fan, BE, De Mel, S, Ooi, M, Jen, WY, Chow, EH. A Combinatorial Functional Precision Medicine Platform for Rapid Therapeutic Response Prediction in AML. Cancer medicine 13(22), 2024. e-Pub 2024. PMID: 39560206.
3. Marvin-Peek J, Jen WY, Ravandi F. Long-term results of the sequential combination of cladribine and rituximab in Hairy cell leukemia. Leuk Lymphoma. e-Pub 2024. PMID: 38749022.
4. Jen WY, Sasaki K, Loghavi S, Wang SA, Qiao W, Borthakur G, Ravandi F, Kadia TM, Issa GC, Short NJ, Yilmaz M, Daver NG, DiNardo CD. Characteristics and outcomes of acute myeloid leukaemia patients with baseline CD7 expression. Br J Haematol. e-Pub 2024. PMID: 38603594.
5. Song Y, Lee SY, Chee Y, Jen WY. Hypertensive Emergency with Thrombotic Microangiopathy or TTP? A Case Series and Literature Review. J Clin Med 13(7):1880, 2024. e-Pub 2024. PMID: 38610645.
6. Jen WY, Sasaki K, Rausch CR, DiNardo CD, Kadia TM, Yilmaz M, Borthakur G, Alvarado Y, McCue D, McCue D, Kantarjian HM, Ravandi F. Acute kidney injury in acute promyelocytic leukemia: a possible adverse effect of high dose arsenic trioxide in obese patients. Leuk Lymphoma 65(3):378-382, 2024. e-Pub 2024. PMID: 38054837.
7. Tan CJ, Yun Tan MS, Nagarajan C, Chng WJ, Chee YL, Ooi M, Kiat Ng LC, Chen Y, Yin Yoong JS, Wong XY, Jen WY. Factors Affecting Patient and Caregiver Preferences for Treatment of Myeloma and Indolent Lymphoma. JCO Oncol Pract 19(12):1168-1178, 2023. e-Pub 2023. PMID: 37844267.
8. Lee SY, Y Teo WZ, Lim CXQ, Lee CT, Jen WY, Mel SD, Yap ES, Chee YL. Venous thromboembolism in an Asian COVID-19 cohort across 3 infection waves—a retrospective observational study. Res Pract Thromb Haemost 7(7):102218, 2023. e-Pub 2023. PMID: 38077823.
9. Jen WY, Chan ZY, Lee YM, Ng N, Tan B, Teo C, Wong YP, Chee CE, Chee YL. Reducing Chemotherapy Waiting Times in the Ambulatory Setting of a Tertiary Cancer Centre Using a Design Thinking Approach. Cancers (Basel) 15(18):4625, 2023. e-Pub 2023. PMID: 37760594.
10. Guo M, Man Chan TH, Zhou Q, An O, Li Y, Song Y, Tan ZH, En Ng VH, Peramangalam PS, Tan ZQ, Cao X, Iwanaga E, Matsuoka M, M Ooi MG, Jen WY, Koh LP, Chan E, Tan LK, Goh Y, Wang W, H Koh BT, Chun CM, Fullwood MJ, Chng WJ, Osato M, Pulikkan JA, Yang H, Chen L, Tenen DG. Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis. Blood 141(25):3078-3090, 2023. e-Pub 2023. PMID: 36796022.
11. Alagha, R, Chan, WL, Edwin, TS, Lee, J, Jen, WY, Lip, CK, Smitasin, N, Somani, J. The Mote in Thy Brother's Eyes - Fusarium Solani in Leukemia Host. Infectious Diseases in Clinical Practice 31(2), 2023. e-Pub 2023.
12. Ong SY, Si Yun MT, Abdul Halim NA, Christopher D, Jen WY, Gallardo C, Hwee Yim AT, Woon YK, Ng HJ, Ooi M, Wong GC. Real-World Experience of Measurable Residual Disease Response and Prognosis in Acute Myeloid Leukemia Treated with Venetoclax and Azacitidine. Cancers (Basel) 14(15):3576, 2022. e-Pub 2022. PMID: 35892834.
13. Ko SQ, Hooi BMY, Koo C, Chor DWP, Ling ZJ, Chee YL, Jen WY. Remote monitoring of marginalised populations affected by COVID-19: a retrospective review. BMJ Open 10(12):e042647, 2020. e-Pub 2020. PMID: 33384398.
14. Jen WY, Kristanto W, Teo L, Phua J, Yip HS, MacLaren G, Teoh K, Sim TB, Loh J, Ong CC, Chee YL, Kojodjojo P. Assessing the impact of a Pulmonary Embolism Response Team and treatment protocol on patients presenting with acute pulmonary embolism. Heart Lung Circ 29(3):2345-353, 2020. e-Pub 2020. PMID: 30910512.
15. Jen WY, Yoong J, Liu X, Tan MSY, Chng WJ, Chee YL. Qualitative study of factors affecting patient, caregiver and physician preferences for treatment of myeloma and indolent lymphoma. Patient Prefer Adherence 17(14):301-308, 2020. e-Pub 2020. PMID: 32109996.
16. Ng CH, Jen WY, Koh LP, Ooi M, CHAN E, ZHOU J, CHNG WJ. A phase 1 study on midostaurin plus panobinostat in unfit acute myeloid leukaemia and high-risk myelodysplastic syndrome. Clin Investig (Lond) 10(2):28-34, 2020. e-Pub 2020.
17. Winata AS, Jen WY, Teng ML, Hing W, Iyer SG, Ma V, Chua H. Intravenous maintenance fluid tonicity and hyponatraemia after major surgery – a cohort study. Int J Surg 67:1-7, 2019. e-Pub 2019. PMID: 31075533.
18. Jen WY, Jeon YS, Kojodjojo P, Er Lee EH, Lee YH, Ren YP, Shawn Tan TJ, Song Y, Zhang T, Teo L, Feng M. A New Model for Risk Stratification of Patients With Acute Pulmonary Embolism. Clin Appl Thromb Hemost 24:277S-284S, 2018. e-Pub 2018. PMID: 30370786.

Other Articles

1. Jen WY, Kantarjian H, Kadia TM, DiNardo CD, Issa GC, Short NJ, Yilmaz M, Borthakur G, Ravandi F, Daver NG Combination therapy with novel agents for acute myeloid leukaemia: Insights into treatment of a heterogenous disease. Br J Haematol. PMID: 38724457.
2. Jen WY, Konopleva M, Pemmaraju N Tagraxofusp, a first-in-class CD123-targeted agent: Five-year postapproval comprehensive review of the literature. Cancer. PMID: 38620053.
3. Jen WY, Jabbour E, Kantarjian HM, Short NJ SOHO State of the Art Updates and Next Questions | Novel Agents and the Diminishing Role of Allogeneic Stem Cell Transplant in B-Acute Lymphoblastic Leukemia. Clin Lymphoma Myeloma Leuk. PMID: 38538495.
4. Thong EWS, Tan SS, Sethi SK, Chee YL, Jen WY Falsely elevated serum vitamin B12 levels in a case of pernicious anemia. Ann Hematol 101(4):889-892, 2022. PMID: 34505941.
5. Yu Ng AP, Chee YL, Wong SBJ, Jen WY Methicillin-resistant Staphylococcus aureus (MRSA) panniculitis in a patient undergoing stem cell mobilization. BMJ Case Rep 14(2):e236382, 2021. PMID: 33563686.
6. Sia CS, Jen WY, Poon MLM Acquired antibody-mediated pure red cell aplasia following treatment with darbepoetin. Ann Acad Med Singap 49(1):46-48, 2020. PMID: 32200397.
7. Jen WY, Chee Y, Khor LK, Nga ME, Poon L, de Mel S Diffuse intrasinusoidal hepatic metastases from occult breast carcinoma presenting as thrombotic microangiopathy: a case report and literature review. J Hematol 4(4):238-241, 2015.

Editorials

1. National University Cancer Institute of Singapore (NCIS) Workflow Team. A segregated-team model to maintain cancer care during the COVID-19 outbreak at an academic center in Singapore. Ann Oncol 31(7):840-843, 2020. PMID: 32243893.

Abstracts

1. Jen WY, Takahashi K, Loghavi S, Kadia T, Daver N, Xiao L, Short NJ, Sasaki K, Wang SA, Borthakur G, Issa G, Maiti A, Alvarado Y, Pemmaraju N, Ferrajoli A, Reville PK, Swaminathan M, Ohanian M, Abbas H, Hammond D, Burger J, Haddad F, Bravo GM, Chien K, Masarova L, Yilmaz M, Jain N, Andreeff M, Garcia-Manero G, Kornblau S, Ravandi F, Jabbour E, Konopleva MY, Mullin JK, Pierce S, Kantarjian HM, DiNardo CD. FLAG-IDA + Venetoclax (VEN) in Newly Diagnosed (ND) or Relapsed / Refractory (RR) AML. European Haematology Association Annual Congress.
2. Jen WY, Teng ML, Hing WC, Ma V, Iyer SG, Chua HR. Hypotonic vs isotonic fluid maintenance on biochemical outcomes after major surgery. 32nd World Congress of Internal Medicine.
3. Jen WY, Chee YL. Validation of the Pulmonary Embolism Severity Index (PESI) and Simplified PESI in Asian patients with pulmonary embolism. International Society on Thrombosis and Haemostasis Congress.
4. Jen WY, Koh LP. Allogeneic haematopoetic cell transplant for adults with Philadelphia chromosome acute lymphoblastic leukaemia in the era of tyrosine kinas inhibitors – a comparative analysis of different donor sources. National University Cancer Institute, Singapore Annual Research Meeting.
5. Jen WY, Chan E. Outpatient administration of infusional-based EPOCH chemotherapy: a single centre experience. Pacific Lymphoma Conference.
6. Jen WY, Chee YL. A new model for risk stratification of acute pulmonary embolism. Thrombosis and Hemostasis Summit of North America.
7. Ngo E, Jen WY. Maximising Capacity and Saving Cost in an Outpatient Chemotherapy Centre during a Pandemic: A Quality Improvement Project. American Society of Hematology.
8. Jen WY, Santoso E, Kumari S, Chee YL. Risk Factors, Mortality and Costs of Cancer-Associated Thrombosis in Hospitalised Patients. International Society on Thrombosis and Haemostasis Congress.
9. Lai EEN, Furqan MS, Chew KL, Poon ML, Chee YL, Jen WY. An algorithm to identify cancer patients who will have a positive blood culture at the time of phlebotomy. European Haematology Association.
10. Wu I, Ngam PI, Ong CC, Kristanto W, Kojodjojo P, Teo L, Chee YL, Jen WY. Radiological Parameters on Computed Tomography Pulmonary Angiography Correlate Poorly with Early Mortality from Acute Pulmonary Embolism. International Society on Thrombosis and Haemostasis Congress.
11. Jen WY, Chee YL. Reducing Time to Chemotherapy Administration in the Outpatient Setting of a Tertiary Cancer Centre Using a Design Thinking Approach. American Society of Hematology.
12. Song Y, Kim JS, Chim CS, Lee J, Yoon S, Ng SC, Gan GG, Handa H, Jen WY, Li X, Pokharkar YM, Durie BG, Chng W. Randomized Phase 3 Study of Pomalidomide Cyclophosphamide Dexamethasone (PCD) Versus Pomalidomide Dexamethasone (PD) in Relapse or Refractory Myeloma: An Asian Myeloma Network (AMN) Study. American Society of Hematology.
13. Thong EWS, Makmur A, Chee YL, Hallihan J, Jit Cheng LT, Kumarakulasinghe NB, Jeyasekharan AD, Xian Lee JS, Mel SD, Li Chan EH, Poon M, Chng W, Jayalakshmi, Ali MD, Jen WY, Wei Lim DS. Development of a Novel Artificial Intelligence Tool to Measure Psoas Volumes in Patients with Diffuse Large B Cell Lymphoma. American Society of Hematology.
14. Wong M, Chan ZY, Quek MY, Koh A, Teo C, Foo J, Chee CE, Wong A, Ow S, Tay J, Luah V, Saw XS, Wong YP, Lee MT, Lee J, Lin C, Chua J, Chng W, Jen WY. Feasibility and Implementation of an Out-of-Pocket Cost Calculator for Pre-Treatment Financial Counselling in Cancer Patients. American Society of Hematology.
15. Jen WY, DiNardo CD, Chien KS, Alvarado-Valero Y, Masarova L, Brandt M, Bull-Linderman D, Daver N, Montalban-Bravo G, Bataller A, Garcia-Manero G, Issa GC, Alousi A, Short NJ, Ravandi F. Phase 2 Study of CPX-351 in Combination with Venetoclax in Patients with Newly Diagnosed, High Risk Acute Myeloid Leukemia. American Society of Hematology.
16. Jen WY, Ooi M, deMel S, Soekojo C, Yoon S, Li X, Awasthi N, Burkill SM, Durie BG, Chng W. A Phase 2 Study of Daratumumab in Combination with Thalidomide and Dexamethasone in Relapsed and / or Refractory Myeloma: A Report from the Asian Myeloma Network. American Society of Hematology.
17. Jen WY, Jabbour E, Haddad FG, Nasr L, Short NJ, Zoghbi M, Nasnas C, Issa GC, Yilmaz M, Daver N, Pemmaraju N, Masarova L, Ravandi F, Jain N, Deen W, Loiselle C, Waller L, Banks G, Garris R, Kantarjian HM. A Phase II Study of Low-Intensity Chemotherapy (Mini-Hyper-CVD) and Ponatinib Followed By Blinatumomab and Ponatinib in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia. American Society of Hematology.
18. Jen WY, Jabbour E, Haddad FG, Short NJ, Jain N, Kadia TM, Daver N, Borthakur G, Nasr L, DiNardo CD, Zoghbi M, Jacob J, Roy E, Loiselle C, Milton A, Rivera J, Garris R, Ravandi F, Kantarjian HM. Phase 2 Trial of Mini-Hyper-CVD Plus Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Patients with Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia. American Society of Hematology.
19. Jen WY, Takahashi K, Loghavi S, Kadia T, Daver N, Xiao L, Short N, Borthakur G, Issa G, Pemmaraju N, Reville P, Bravo G, Yilmaz M, Garcia-Manero G, Ravandi-Kashani F, Konopleva M, Mullin J, Pierce S, Kantarjian H, DiNardo CD. FLAG-IDA + Venetoclax (VEN) in Newly Diagnosed (ND) or Relapsed / Refractory (RR) AML. American Society of Clinical Oncology.

Letters to the Editor

1. Jen, WY, Jabbour, EJ, Short, NJ, Issa, GC, Haddad, FG, Jain, N, Pemmaraju, N, Daver, N, Masarova, L, Borthakur, G, Chien, KS, Garris, R, Kantarjian, H. A phase 2 trial of mini-hyper-CVD, blinatumomab, and ponatinib in Philadelphia positive acute lymphoblastic leukemia. American journal of hematology 99: 2229-2232, 2024.
2. Olesinski EA, Bhatia KS, Mahesh AN, Rosli S, Mohamed JS, Jen WY, Jain N, Garcia JS, Wong GC, Ooi M, Letai A, Konopleva M, Bhatt S. BH3 profiling identifies BCL-2 dependence in adult patients with early T-cell progenitor acute lymphoblastic leukemia. Blood Adv 7: 2917-2923, 2023.
3. Cheong MA, Chee Y, Ng HJ, Jen WY. Keeping the bloodline of haematology medical education flowing during a pandemic. Int J Lab Hematol 42: e196-e198, 2020.